387631:ASULF RS00595
gene id: 387631:ASULF_RS00595
uniprot id: N0BAX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: Located at the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS09105
gene id: 387631:ASULF_RS09105
uniprot id: N0BFN1
names: Similarity
messages: Belongs to the peptidase S8 family.

387631:ASULF RS05570
gene id: 387631:ASULF_RS05570
uniprot id: N0BDP4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

387631:ASULF RS03945
gene id: 387631:ASULF_RS03945
uniprot id: N0BKR7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

387631:ASULF RS08395
gene id: 387631:ASULF_RS08395
uniprot id: N0BHA8
names: Function
messages: Part of a potassium transport system.

387631:ASULF RS03430
gene id: 387631:ASULF_RS03430
uniprot id: N0BJN8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

387631:ASULF RS05410
gene id: 387631:ASULF_RS05410
uniprot id: N0BFP6
names: Similarity
messages: Belongs to the TlyA family.

387631:ASULF RS01460
gene id: 387631:ASULF_RS01460
uniprot id: N0BBD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS01945
gene id: 387631:ASULF_RS01945
uniprot id: N0BJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS01385
gene id: 387631:ASULF_RS01385
uniprot id: N0BBC3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

387631:ASULF RS03020
gene id: 387631:ASULF_RS03020
uniprot id: N0BJH8
names: Similarity
messages: Belongs to the Ahb/Nir family.

387631:ASULF RS01735
gene id: 387631:ASULF_RS01735
uniprot id: N0BIS4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

387631:ASULF RS02925
gene id: 387631:ASULF_RS02925
uniprot id: N0BJG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

387631:ASULF RS01145
gene id: 387631:ASULF_RS01145
uniprot id: N0BJC1
names: Similarity
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.

387631:ASULF RS09890
gene id: 387631:ASULF_RS09890
uniprot id: N0BN17
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

387631:ASULF RS06340
gene id: 387631:ASULF_RS06340
uniprot id: N0BCD6
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

387631:ASULF RS02655
gene id: 387631:ASULF_RS02655
uniprot id: N0BK88
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

387631:ASULF RS10210
gene id: 387631:ASULF_RS10210
uniprot id: N0BEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm

387631:ASULF RS10145
gene id: 387631:ASULF_RS10145
uniprot id: N0BGD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS08925
gene id: 387631:ASULF_RS08925
uniprot id: N0BDU7
names: Similarity
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.

387631:ASULF RS10495
gene id: 387631:ASULF_RS10495
uniprot id: N0BIH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SepCysS family.
messages: Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
messages: Homodimer. Interacts with SepRS.

387631:ASULF RS03760
gene id: 387631:ASULF_RS03760
uniprot id: N0BJU4
names: Similarity
messages: Belongs to the UPF0235 family.

387631:ASULF RS08400
gene id: 387631:ASULF_RS08400
uniprot id: N0BF99
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS08600
gene id: 387631:ASULF_RS08600
uniprot id: N0BFD6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

387631:ASULF RS09710
gene id: 387631:ASULF_RS09710
uniprot id: N0BMX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

387631:ASULF RS02485
gene id: 387631:ASULF_RS02485
uniprot id: N0BJ97
names: Similarity
messages: Belongs to the peptidase M20A family.

387631:ASULF RS09880
gene id: 387631:ASULF_RS09880
uniprot id: N0BEF6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DtdA deacylase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
messages: Monomer.

387631:ASULF RS00500
gene id: 387631:ASULF_RS00500
uniprot id: N0B934
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

387631:ASULF RS06835
gene id: 387631:ASULF_RS06835
uniprot id: N0BGG0
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

387631:ASULF RS05750
gene id: 387631:ASULF_RS05750
uniprot id: N0BFU3
names: Similarity
messages: Belongs to the thioesterase PaaI family.

387631:ASULF RS03150
gene id: 387631:ASULF_RS03150
uniprot id: N0BJJ9
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

387631:ASULF RS05130
gene id: 387631:ASULF_RS05130
uniprot id: N0BDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

387631:ASULF RS06370
gene id: 387631:ASULF_RS06370
uniprot id: N0BLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

387631:ASULF RS11400
gene id: 387631:ASULF_RS11400
uniprot id: N0BM16
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

387631:ASULF RS01745
gene id: 387631:ASULF_RS01745
uniprot id: N0BBJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

387631:ASULF RS09175
gene id: 387631:ASULF_RS09175
uniprot id: N0BHR3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Binds 2 Mg(2+) or Mn(2+) ions per subunit.
messages: Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS03405
gene id: 387631:ASULF_RS03405
uniprot id: N0BJN4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

387631:ASULF RS01200
gene id: 387631:ASULF_RS01200
uniprot id: N0BIH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

387631:ASULF RS06400
gene id: 387631:ASULF_RS06400
uniprot id: N0BL72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Membrane

387631:ASULF RS12275
gene id: 387631:ASULF_RS12275
uniprot id: N0BAL4
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS00570
gene id: 387631:ASULF_RS00570
uniprot id: N0BAX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

387631:ASULF RS02190
gene id: 387631:ASULF_RS02190
uniprot id: N0BK08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGGP/HepGP synthase family. Group I subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

387631:ASULF RS00440
gene id: 387631:ASULF_RS00440
uniprot id: N0BD10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Spt4 family.
messages: Heterodimer composed of Spt4 and Spt5.
messages: Stimulates transcription elongation.

387631:ASULF RS03685
gene id: 387631:ASULF_RS03685
uniprot id: N0BJT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-alpha family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

387631:ASULF RS06140
gene id: 387631:ASULF_RS06140
uniprot id: N0BLV9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

387631:ASULF RS08930
gene id: 387631:ASULF_RS08930
uniprot id: N0BNB8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

387631:ASULF RS02040
gene id: 387631:ASULF_RS02040
uniprot id: N0BJX6
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS08225
gene id: 387631:ASULF_RS08225
uniprot id: N0BM38
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

387631:ASULF RS07005
gene id: 387631:ASULF_RS07005
uniprot id: N0BLJ9
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

387631:ASULF RS08115
gene id: 387631:ASULF_RS08115
uniprot id: N0BMY5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

387631:ASULF RS10860
gene id: 387631:ASULF_RS10860
uniprot id: N0BIM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

387631:ASULF RS03445
gene id: 387631:ASULF_RS03445
uniprot id: N0BAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

387631:ASULF RS02235
gene id: 387631:ASULF_RS02235
uniprot id: N0BA60
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
messages: Belongs to the GatB/GatE family. GatE subfamily.
messages: Heterodimer of GatD and GatE.

387631:ASULF RS02395
gene id: 387631:ASULF_RS02395
uniprot id: N0BJ83
names: Similarity
messages: Belongs to the AAA ATPase family.

387631:ASULF RS10280
gene id: 387631:ASULF_RS10280
uniprot id: N0BGF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

387631:ASULF RS00585
gene id: 387631:ASULF_RS00585
uniprot id: N0BI73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

387631:ASULF RS02330
gene id: 387631:ASULF_RS02330
uniprot id: N0BBX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mer family.
messages: Catalyzes the oxidation of methyl-H(4)MPT to methylene-H(4)MPT.
messages: Cytoplasm

387631:ASULF RS05010
gene id: 387631:ASULF_RS05010
uniprot id: N0BBQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

387631:ASULF RS04130
gene id: 387631:ASULF_RS04130
uniprot id: N0BKV2
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.

387631:ASULF RS09525
gene id: 387631:ASULF_RS09525
uniprot id: N0BNM4
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS03295
gene id: 387631:ASULF_RS03295
uniprot id: N0BAP6
names: Similarity
messages: Belongs to the UPF0212 family.

387631:ASULF RS10115
gene id: 387631:ASULF_RS10115
uniprot id: N0BID0
names: Similarity
messages: Belongs to the P(II) protein family.

387631:ASULF RS10695
gene id: 387631:ASULF_RS10695
uniprot id: N0BES8
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

387631:ASULF RS02665
gene id: 387631:ASULF_RS02665
uniprot id: N0BEA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isopentenyl phosphate kinase family.
messages: Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids.
messages: Homodimer.

387631:ASULF RS02575
gene id: 387631:ASULF_RS02575
uniprot id: N0BK79
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

387631:ASULF RS00425
gene id: 387631:ASULF_RS00425
uniprot id: N0B916
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS31 family.
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS02150
gene id: 387631:ASULF_RS02150
uniprot id: N0BE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

387631:ASULF RS00185
gene id: 387631:ASULF_RS00185
uniprot id: N0BAQ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02755
gene id: 387631:ASULF_RS02755
uniprot id: N0BKA1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

387631:ASULF RS01235
gene id: 387631:ASULF_RS01235
uniprot id: N0BB94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofC family.
messages: Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
messages: Homodimer.

387631:ASULF RS09725
gene id: 387631:ASULF_RS09725
uniprot id: N0BEC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

387631:ASULF RS09435
gene id: 387631:ASULF_RS09435
uniprot id: N0BMQ6
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

387631:ASULF RS08005
gene id: 387631:ASULF_RS08005
uniprot id: N0BF18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

387631:ASULF RS11150
gene id: 387631:ASULF_RS11150
uniprot id: N0BPE5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

387631:ASULF RS00775
gene id: 387631:ASULF_RS00775
uniprot id: N0BD67
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

387631:ASULF RS11020
gene id: 387631:ASULF_RS11020
uniprot id: N0BPC4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

387631:ASULF RS00340
gene id: 387631:ASULF_RS00340
uniprot id: N0BAT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

387631:ASULF RS08055
gene id: 387631:ASULF_RS08055
uniprot id: N0BF30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

387631:ASULF RS10870
gene id: 387631:ASULF_RS10870
uniprot id: N0BEV7
names: Similarity
messages: Belongs to the SDO1/SBDS family.

387631:ASULF RS10650
gene id: 387631:ASULF_RS10650
uniprot id: N0BP59
names: Similarity
messages: Belongs to the AOR/FOR family.

387631:ASULF RS09625
gene id: 387631:ASULF_RS09625
uniprot id: N0BNP1
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

387631:ASULF RS00265
gene id: 387631:ASULF_RS00265
uniprot id: N0B8Z3
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS05375
gene id: 387631:ASULF_RS05375
uniprot id: N0BLK3
names: Similarity
messages: Belongs to the UPF0200 family.
messages: Belongs to the UPF0201 family.

387631:ASULF RS07080
gene id: 387631:ASULF_RS07080
uniprot id: N0BLL5
names: Similarity
messages: Belongs to the aspartokinase family.

387631:ASULF RS09365
gene id: 387631:ASULF_RS09365
uniprot id: N0BHV7
names: Caution
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS03460
gene id: 387631:ASULF_RS03460
uniprot id: N0BEL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Participates in transcription termination.

387631:ASULF RS02275
gene id: 387631:ASULF_RS02275
uniprot id: N0BE39
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

387631:ASULF RS00790
gene id: 387631:ASULF_RS00790
uniprot id: N0BJ47
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

387631:ASULF RS00540
gene id: 387631:ASULF_RS00540
uniprot id: N0BD24
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS04060
gene id: 387631:ASULF_RS04060
uniprot id: N0BJZ9
names: Function
names: Similarity
messages: Belongs to the archaeal 6-HMPDK family.
messages: Catalyzes the transfer of diphosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP).

387631:ASULF RS10585
gene id: 387631:ASULF_RS10585
uniprot id: N0BER4
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10240
gene id: 387631:ASULF_RS10240
uniprot id: N0BNZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.

387631:ASULF RS10255
gene id: 387631:ASULF_RS10255
uniprot id: N0BGE8
names: Subcellular Location Annotation
messages: Mitochondrion

387631:ASULF RS09380
gene id: 387631:ASULF_RS09380
uniprot id: N0BNJ8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

387631:ASULF RS02795
gene id: 387631:ASULF_RS02795
uniprot id: N0BC73
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

387631:ASULF RS10855
gene id: 387631:ASULF_RS10855
uniprot id: N0BNE7
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

387631:ASULF RS10260
gene id: 387631:ASULF_RS10260
uniprot id: N0BEL6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

387631:ASULF RS05790
gene id: 387631:ASULF_RS05790
uniprot id: N0BFU9
names: Similarity
messages: Belongs to the UPF0310 family.

387631:ASULF RS03285
gene id: 387631:ASULF_RS03285
uniprot id: N0BEI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta-RFA-P synthase family.
messages: Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
messages: Homodimer.

387631:ASULF RS00610
gene id: 387631:ASULF_RS00610
uniprot id: N0BI78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

387631:ASULF RS08145
gene id: 387631:ASULF_RS08145
uniprot id: N0BM28
names: Similarity
messages: Belongs to the class-I fumarase family.

387631:ASULF RS03475
gene id: 387631:ASULF_RS03475
uniprot id: N0BKJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds at least 2 Zn(2+) per subunit.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

387631:ASULF RS05295
gene id: 387631:ASULF_RS05295
uniprot id: N0BBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

387631:ASULF RS00430
gene id: 387631:ASULF_RS00430
uniprot id: N0BIZ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

387631:ASULF RS04515
gene id: 387631:ASULF_RS04515
uniprot id: N0BK89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

387631:ASULF RS10030
gene id: 387631:ASULF_RS10030
uniprot id: N0BNX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. Probably involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.
messages: Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.

387631:ASULF RS08110
gene id: 387631:ASULF_RS08110
uniprot id: N0BDD5
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS00575
gene id: 387631:ASULF_RS00575
uniprot id: N0B952
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS03525
gene id: 387631:ASULF_RS03525
uniprot id: N0BAU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

387631:ASULF RS01355
gene id: 387631:ASULF_RS01355
uniprot id: N0BDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

387631:ASULF RS07605
gene id: 387631:ASULF_RS07605
uniprot id: N0BGZ5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

387631:ASULF RS03770
gene id: 387631:ASULF_RS03770
uniprot id: N0BCN5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

387631:ASULF RS00865
gene id: 387631:ASULF_RS00865
uniprot id: N0BJ59
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS01245
gene id: 387631:ASULF_RS01245
uniprot id: N0BJE6
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS09040
gene id: 387631:ASULF_RS09040
uniprot id: N0BMG8
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS07900
gene id: 387631:ASULF_RS07900
uniprot id: N0BF05
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
messages: Monomer.
messages: The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity.

387631:ASULF RS04505
gene id: 387631:ASULF_RS04505
uniprot id: N0BBD7
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02780
gene id: 387631:ASULF_RS02780
uniprot id: N0BKA3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

387631:ASULF RS08560
gene id: 387631:ASULF_RS08560
uniprot id: N0BN50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

387631:ASULF RS10830
gene id: 387631:ASULF_RS10830
uniprot id: N0BNE5
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

387631:ASULF RS09885
gene id: 387631:ASULF_RS09885
uniprot id: N0BNT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

387631:ASULF RS08965
gene id: 387631:ASULF_RS08965
uniprot id: N0BMF5
names: Similarity
messages: Belongs to the AAA ATPase family.

387631:ASULF RS01550
gene id: 387631:ASULF_RS01550
uniprot id: N0BIP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

387631:ASULF RS09705
gene id: 387631:ASULF_RS09705
uniprot id: N0BNQ5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

387631:ASULF RS10680
gene id: 387631:ASULF_RS10680
uniprot id: N0BNC4
names: Similarity
messages: Belongs to the LarC family.

387631:ASULF RS00935
gene id: 387631:ASULF_RS00935
uniprot id: N0B9D2
names: Similarity
messages: Belongs to the glutamine synthetase family.

387631:ASULF RS02175
gene id: 387631:ASULF_RS02175
uniprot id: N0BE15
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS01600
gene id: 387631:ASULF_RS01600
uniprot id: N0BIQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS04390
gene id: 387631:ASULF_RS04390
uniprot id: N0BF42
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

387631:ASULF RS10485
gene id: 387631:ASULF_RS10485
uniprot id: N0BP34
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

387631:ASULF RS03045
gene id: 387631:ASULF_RS03045
uniprot id: N0BKD8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

387631:ASULF RS00550
gene id: 387631:ASULF_RS00550
uniprot id: N0B947
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Part of the 30S ribosomal subunit. Contacts protein S4.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

387631:ASULF RS11205
gene id: 387631:ASULF_RS11205
uniprot id: N0BNK0
names: Similarity
messages: Belongs to the UPF0175 family.

387631:ASULF RS09720
gene id: 387631:ASULF_RS09720
uniprot id: N0BG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
messages: Cytoplasm

387631:ASULF RS01560
gene id: 387631:ASULF_RS01560
uniprot id: N0BBG0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02580
gene id: 387631:ASULF_RS02580
uniprot id: N0BJB2
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family.
messages: Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).

387631:ASULF RS00640
gene id: 387631:ASULF_RS00640
uniprot id: N0BD42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29.

387631:ASULF RS09680
gene id: 387631:ASULF_RS09680
uniprot id: N0BMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

387631:ASULF RS09340
gene id: 387631:ASULF_RS09340
uniprot id: N0BMN2
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

387631:ASULF RS05665
gene id: 387631:ASULF_RS05665
uniprot id: N0BFT2
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

387631:ASULF RS06080
gene id: 387631:ASULF_RS06080
uniprot id: N0BFZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Ni-containing carbon monoxide dehydrogenase family.
messages: CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
messages: Homodimer.

387631:ASULF RS05080
gene id: 387631:ASULF_RS05080
uniprot id: N0BDG1
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS06245
gene id: 387631:ASULF_RS06245
uniprot id: N0BL42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

387631:ASULF RS04800
gene id: 387631:ASULF_RS04800
uniprot id: N0BD94
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

387631:ASULF RS04610
gene id: 387631:ASULF_RS04610
uniprot id: N0BD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS00525
gene id: 387631:ASULF_RS00525
uniprot id: N0B939
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 2 subfamily.
messages: Cytoplasm

387631:ASULF RS02915
gene id: 387631:ASULF_RS02915
uniprot id: N0BAH7
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

387631:ASULF RS10755
gene id: 387631:ASULF_RS10755
uniprot id: N0BND4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

387631:ASULF RS07940
gene id: 387631:ASULF_RS07940
uniprot id: N0BM04
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS04975
gene id: 387631:ASULF_RS04975
uniprot id: N0BDE4
names: Similarity
messages: Belongs to the glutaredoxin family.

387631:ASULF RS01950
gene id: 387631:ASULF_RS01950
uniprot id: N0BIW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS09595
gene id: 387631:ASULF_RS09595
uniprot id: N0BE89
names: Similarity
messages: Belongs to the band 7/mec-2 family.

387631:ASULF RS00180
gene id: 387631:ASULF_RS00180
uniprot id: N0BCX0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS09655
gene id: 387631:ASULF_RS09655
uniprot id: N0BMW2
names: Subunit
messages: Homotetramer.

387631:ASULF RS10545
gene id: 387631:ASULF_RS10545
uniprot id: N0BNA6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

387631:ASULF RS04845
gene id: 387631:ASULF_RS04845
uniprot id: N0BFF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.

387631:ASULF RS08625
gene id: 387631:ASULF_RS08625
uniprot id: N0BFD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

387631:ASULF RS06260
gene id: 387631:ASULF_RS06260
uniprot id: N0BCC1
names: Similarity
messages: Belongs to the archaeal-type GPI family.

387631:ASULF RS08495
gene id: 387631:ASULF_RS08495
uniprot id: N0BHC2
names: Similarity
messages: Belongs to the complex I subunit 3 family.

387631:ASULF RS08725
gene id: 387631:ASULF_RS08725
uniprot id: N0BDQ4
names: Similarity
messages: Belongs to the snRNP Sm proteins family.

387631:ASULF RS02205
gene id: 387631:ASULF_RS02205
uniprot id: N0BBU7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS09510
gene id: 387631:ASULF_RS09510
uniprot id: N0BHZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CetZ family.
messages: Cytoplasm
messages: Involved in cell shape control.

387631:ASULF RS03220
gene id: 387631:ASULF_RS03220
uniprot id: N0BKG2
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

387631:ASULF RS02505
gene id: 387631:ASULF_RS02505
uniprot id: N0BK73
names: Similarity
messages: Belongs to the CutA family.

387631:ASULF RS00560
gene id: 387631:ASULF_RS00560
uniprot id: N0BI70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS11195
gene id: 387631:ASULF_RS11195
uniprot id: N0BF08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

387631:ASULF RS03985
gene id: 387631:ASULF_RS03985
uniprot id: N0BJY3
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

387631:ASULF RS01315
gene id: 387631:ASULF_RS01315
uniprot id: N0B9L6
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS01695
gene id: 387631:ASULF_RS01695
uniprot id: N0BJP9
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS04475
gene id: 387631:ASULF_RS04475
uniprot id: N0BBD1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

387631:ASULF RS00255
gene id: 387631:ASULF_RS00255
uniprot id: N0BCY4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

387631:ASULF RS06390
gene id: 387631:ASULF_RS06390
uniprot id: N0BCE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

387631:ASULF RS10930
gene id: 387631:ASULF_RS10930
uniprot id: N0BNF9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

387631:ASULF RS07705
gene id: 387631:ASULF_RS07705
uniprot id: N0BH09
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

387631:ASULF RS10065
gene id: 387631:ASULF_RS10065
uniprot id: N0BIC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. Hel308 subfamily.
messages: DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
messages: Monomer.

387631:ASULF RS08885
gene id: 387631:ASULF_RS08885
uniprot id: N0BMD9
names: Similarity
messages: Belongs to the UPF0280 family.

387631:ASULF RS07655
gene id: 387631:ASULF_RS07655
uniprot id: N0BH02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Cytoplasm
messages: Functions by promoting the formation of the first peptide bond.

387631:ASULF RS01225
gene id: 387631:ASULF_RS01225
uniprot id: N0BII2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTH2 family.
messages: Cytoplasm
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

387631:ASULF RS07055
gene id: 387631:ASULF_RS07055
uniprot id: N0BLL0
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

387631:ASULF RS08230
gene id: 387631:ASULF_RS08230
uniprot id: N0BH81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

387631:ASULF RS02610
gene id: 387631:ASULF_RS02610
uniprot id: N0BE99
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

387631:ASULF RS05395
gene id: 387631:ASULF_RS05395
uniprot id: N0BBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

387631:ASULF RS07730
gene id: 387631:ASULF_RS07730
uniprot id: N0BH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS06380
gene id: 387631:ASULF_RS06380
uniprot id: N0BG61
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

387631:ASULF RS10715
gene id: 387631:ASULF_RS10715
uniprot id: N0BGL4
names: Function
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

387631:ASULF RS03485
gene id: 387631:ASULF_RS03485
uniprot id: N0BEM1
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Part of the RNA polymerase complex.

387631:ASULF RS04045
gene id: 387631:ASULF_RS04045
uniprot id: N0BCS9
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS03660
gene id: 387631:ASULF_RS03660
uniprot id: N0BCL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

387631:ASULF RS02660
gene id: 387631:ASULF_RS02660
uniprot id: N0BJC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS03960
gene id: 387631:ASULF_RS03960
uniprot id: N0BCR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

387631:ASULF RS01090
gene id: 387631:ASULF_RS01090
uniprot id: N0B9G6
names: Similarity
messages: Belongs to the FTR family.

387631:ASULF RS04320
gene id: 387631:ASULF_RS04320
uniprot id: N0BCY8
names: Similarity
messages: Belongs to the UPF0179 family.

387631:ASULF RS10250
gene id: 387631:ASULF_RS10250
uniprot id: N0BIE5
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

387631:ASULF RS00095
gene id: 387631:ASULF_RS00095
uniprot id: N0BI00
names: Similarity
messages: Belongs to the acylphosphatase family.

387631:ASULF RS10720
gene id: 387631:ASULF_RS10720
uniprot id: N0BET3
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

387631:ASULF RS03300
gene id: 387631:ASULF_RS03300
uniprot id: N0BKH3
names: Similarity
messages: Belongs to the HerA family.

387631:ASULF RS02340
gene id: 387631:ASULF_RS02340
uniprot id: N0BK43
names: Similarity
messages: Belongs to the peptidase S45 family.

387631:ASULF RS03805
gene id: 387631:ASULF_RS03805
uniprot id: N0BKP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

387631:ASULF RS07640
gene id: 387631:ASULF_RS07640
uniprot id: N0BD65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

387631:ASULF RS08670
gene id: 387631:ASULF_RS08670
uniprot id: N0BFE9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL40 family.

387631:ASULF RS02615
gene id: 387631:ASULF_RS02615
uniprot id: N0BC43
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

387631:ASULF RS00735
gene id: 387631:ASULF_RS00735
uniprot id: N0B985
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

387631:ASULF RS09650
gene id: 387631:ASULF_RS09650
uniprot id: N0BNP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. TrmY family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs.

387631:ASULF RS03895
gene id: 387631:ASULF_RS03895
uniprot id: N0BKQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

387631:ASULF RS01195
gene id: 387631:ASULF_RS01195
uniprot id: N0BJD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC61-beta family.
messages: Cell membrane
messages: Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.
messages: Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
messages: Membrane

387631:ASULF RS04265
gene id: 387631:ASULF_RS04265
uniprot id: N0BF14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

387631:ASULF RS01880
gene id: 387631:ASULF_RS01880
uniprot id: N0BJU0
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS09615
gene id: 387631:ASULF_RS09615
uniprot id: N0BFZ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

387631:ASULF RS04405
gene id: 387631:ASULF_RS04405
uniprot id: N0BL07
names: Similarity
messages: Belongs to the PrpD family.

387631:ASULF RS08615
gene id: 387631:ASULF_RS08615
uniprot id: N0BM93
names: Function
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
messages: Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.

387631:ASULF RS09875
gene id: 387631:ASULF_RS09875
uniprot id: N0BG73
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Ni-containing carbon monoxide dehydrogenase family.
messages: Binds 2 [Ni-4Fe-4S] clusters per heterotetramer.
messages: Binds 7 [4Fe-4S] clusters per heterotetramer.
messages: Cluster B is an all-cysteinyl-liganded 4Fe-4S cluster; cluster C is a mixed Ni-Fe-S cluster which is the active site of CO oxidation. Cluster D is also an all-cysteinyl-liganded 4Fe-4S cluster that bridges the two subunits of the CODH dimer. Contains two additional 4Fe-4S clusters, dubbed E and F, that probably transport electrons from ferredoxin to the B cluster.
messages: Heterotetramer of two alpha and two epsilon subunits. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta subunits with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.

387631:ASULF RS02385
gene id: 387631:ASULF_RS02385
uniprot id: N0BA96
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

387631:ASULF RS06185
gene id: 387631:ASULF_RS06185
uniprot id: N0BCA3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-A/Apern subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

387631:ASULF RS07735
gene id: 387631:ASULF_RS07735
uniprot id: N0BEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS03585
gene id: 387631:ASULF_RS03585
uniprot id: N0BCK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAC-alpha family.
messages: Contacts the emerging nascent chain on the ribosome.
messages: Homodimer. Interacts with the ribosome. Binds ribosomal RNA.

387631:ASULF RS01705
gene id: 387631:ASULF_RS01705
uniprot id: N0BDQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate.
messages: Homodimer.

387631:ASULF RS08735
gene id: 387631:ASULF_RS08735
uniprot id: N0BMB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
messages: Binds 1 zinc ion per subunit.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

387631:ASULF RS08200
gene id: 387631:ASULF_RS08200
uniprot id: N0BM35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aTrm56 family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.

387631:ASULF RS06135
gene id: 387631:ASULF_RS06135
uniprot id: N0BC93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS01095
gene id: 387631:ASULF_RS01095
uniprot id: N0BJA7
names: Function
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

387631:ASULF RS06225
gene id: 387631:ASULF_RS06225
uniprot id: N0BG29
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS10915
gene id: 387631:ASULF_RS10915
uniprot id: N0BGQ4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

387631:ASULF RS02120
gene id: 387631:ASULF_RS02120
uniprot id: N0BJ09
names: Similarity
messages: Belongs to the malic enzymes family.

387631:ASULF RS07810
gene id: 387631:ASULF_RS07810
uniprot id: N0BD91
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS10980
gene id: 387631:ASULF_RS10980
uniprot id: N0BIP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

387631:ASULF RS03415
gene id: 387631:ASULF_RS03415
uniprot id: N0BCI0
names: Caution
names: Function
names: Similarity
messages: Belongs to the TBP family.
messages: General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS09030
gene id: 387631:ASULF_RS09030
uniprot id: N0BDW9
names: Similarity
messages: Belongs to the AOR/FOR family.

387631:ASULF RS03795
gene id: 387631:ASULF_RS03795
uniprot id: N0BCP0
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

387631:ASULF RS08640
gene id: 387631:ASULF_RS08640
uniprot id: N0BM97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS11225
gene id: 387631:ASULF_RS11225
uniprot id: N0BPG0
names: Function
names: Subunit
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

387631:ASULF RS05730
gene id: 387631:ASULF_RS05730
uniprot id: N0BDS1
names: Function
names: Similarity
messages: Belongs to the archaeal SPP-like hydrolase family.
messages: Catalyzes the dephosphorylation of 2-phosphoglycolate.

387631:ASULF RS00085
gene id: 387631:ASULF_RS00085
uniprot id: N0BAN8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS01775
gene id: 387631:ASULF_RS01775
uniprot id: N0B9W1
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10110
gene id: 387631:ASULF_RS10110
uniprot id: N0BN57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS10040
gene id: 387631:ASULF_RS10040
uniprot id: N0BIB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

387631:ASULF RS04990
gene id: 387631:ASULF_RS04990
uniprot id: N0BKJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
messages: Belongs to the TiaS family.
messages: Cytoplasm

387631:ASULF RS05580
gene id: 387631:ASULF_RS05580
uniprot id: N0BLM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

387631:ASULF RS00685
gene id: 387631:ASULF_RS00685
uniprot id: N0BI88
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

387631:ASULF RS03265
gene id: 387631:ASULF_RS03265
uniprot id: N0BCF4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

387631:ASULF RS05415
gene id: 387631:ASULF_RS05415
uniprot id: N0BDL9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

387631:ASULF RS01020
gene id: 387631:ASULF_RS01020
uniprot id: N0BJ90
names: Similarity
messages: Belongs to the glutamine synthetase family.

387631:ASULF RS00445
gene id: 387631:ASULF_RS00445
uniprot id: N0BAV1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.
messages: Nucleus
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.

387631:ASULF RS00990
gene id: 387631:ASULF_RS00990
uniprot id: N0B9E3
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

387631:ASULF RS03085
gene id: 387631:ASULF_RS03085
uniprot id: N0BCC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS08215
gene id: 387631:ASULF_RS08215
uniprot id: N0BDF1
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

387631:ASULF RS01325
gene id: 387631:ASULF_RS01325
uniprot id: N0BIK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

387631:ASULF RS04670
gene id: 387631:ASULF_RS04670
uniprot id: N0BKC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
messages: Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
messages: Homodecamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS10970
gene id: 387631:ASULF_RS10970
uniprot id: N0BPB5
names: Similarity
messages: Belongs to the UbiD family.

387631:ASULF RS08990
gene id: 387631:ASULF_RS08990
uniprot id: N0BMF9
names: Function
names: Similarity
messages: Belongs to the adenylate cyclase family. DacZ subfamily.
messages: Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.

387631:ASULF RS03215
gene id: 387631:ASULF_RS03215
uniprot id: N0BAM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

387631:ASULF RS08585
gene id: 387631:ASULF_RS08585
uniprot id: N0BN55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

387631:ASULF RS06250
gene id: 387631:ASULF_RS06250
uniprot id: N0BG35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.
messages: Belongs to the Holliday junction resolvase Hjc family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.

387631:ASULF RS04240
gene id: 387631:ASULF_RS04240
uniprot id: N0BF10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

387631:ASULF RS10385
gene id: 387631:ASULF_RS10385
uniprot id: N0BN87
names: Similarity
messages: Belongs to the AOR/FOR family.

387631:ASULF RS10180
gene id: 387631:ASULF_RS10180
uniprot id: N0BEK3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

387631:ASULF RS05125
gene id: 387631:ASULF_RS05125
uniprot id: N0BFL0
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS09635
gene id: 387631:ASULF_RS09635
uniprot id: N0BI26
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

387631:ASULF RS06970
gene id: 387631:ASULF_RS06970
uniprot id: N0BEG7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS10675
gene id: 387631:ASULF_RS10675
uniprot id: N0BP64
names: Similarity
messages: Belongs to the AAA ATPase family. CDC48 subfamily.

387631:ASULF RS01620
gene id: 387631:ASULF_RS01620
uniprot id: N0BJM9
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

387631:ASULF RS09585
gene id: 387631:ASULF_RS09585
uniprot id: N0BI15
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily.
messages: Has ATPase and non-specific DNA-binding activities.

387631:ASULF RS02195
gene id: 387631:ASULF_RS02195
uniprot id: N0BJ27
names: Subcellular Location Annotation
messages: Cell membrane

387631:ASULF RS11120
gene id: 387631:ASULF_RS11120
uniprot id: N0BEZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02050
gene id: 387631:ASULF_RS02050
uniprot id: N0BDY4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Potential transporter for phosphate.

387631:ASULF RS01450
gene id: 387631:ASULF_RS01450
uniprot id: N0BIM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
messages: Heterodimer of a small subunit (PriS) and a large subunit (PriL).
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

387631:ASULF RS00745
gene id: 387631:ASULF_RS00745
uniprot id: N0BI95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic CoaD family.
messages: Cytoplasm
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

387631:ASULF RS07755
gene id: 387631:ASULF_RS07755
uniprot id: N0BEY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

387631:ASULF RS02245
gene id: 387631:ASULF_RS02245
uniprot id: N0BJ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

387631:ASULF RS08840
gene id: 387631:ASULF_RS08840
uniprot id: N0BHJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

387631:ASULF RS09520
gene id: 387631:ASULF_RS09520
uniprot id: N0BE70
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

387631:ASULF RS01660
gene id: 387631:ASULF_RS01660
uniprot id: N0BBH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

387631:ASULF RS00650
gene id: 387631:ASULF_RS00650
uniprot id: N0B968
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.

387631:ASULF RS05885
gene id: 387631:ASULF_RS05885
uniprot id: N0BDV3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS05625
gene id: 387631:ASULF_RS05625
uniprot id: N0BBY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

387631:ASULF RS10125
gene id: 387631:ASULF_RS10125
uniprot id: N0BEJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

387631:ASULF RS00375
gene id: 387631:ASULF_RS00375
uniprot id: N0BIY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS19 family.
messages: May be involved in maturation of the 30S ribosomal subunit.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS02405
gene id: 387631:ASULF_RS02405
uniprot id: N0BC09
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Homodimer.

387631:ASULF RS09620
gene id: 387631:ASULF_RS09620
uniprot id: N0BE95
names: Similarity
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

387631:ASULF RS00365
gene id: 387631:ASULF_RS00365
uniprot id: N0BAT6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

387631:ASULF RS04650
gene id: 387631:ASULF_RS04650
uniprot id: N0BFA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

387631:ASULF RS00940
gene id: 387631:ASULF_RS00940
uniprot id: N0BJ72
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS04275
gene id: 387631:ASULF_RS04275
uniprot id: N0BB86
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS03590
gene id: 387631:ASULF_RS03590
uniprot id: N0BAV5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

387631:ASULF RS03920
gene id: 387631:ASULF_RS03920
uniprot id: N0BKR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS08810
gene id: 387631:ASULF_RS08810
uniprot id: N0BMC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

387631:ASULF RS09735
gene id: 387631:ASULF_RS09735
uniprot id: N0BMY0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

387631:ASULF RS02900
gene id: 387631:ASULF_RS02900
uniprot id: N0BAH4
names: Similarity
messages: Belongs to the glutamate synthase family.

387631:ASULF RS03290
gene id: 387631:ASULF_RS03290
uniprot id: N0BCF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

387631:ASULF RS08150
gene id: 387631:ASULF_RS08150
uniprot id: N0BH71
names: Similarity
messages: Belongs to the class-I fumarase family.

387631:ASULF RS03080
gene id: 387631:ASULF_RS03080
uniprot id: N0BEF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

387631:ASULF RS04850
gene id: 387631:ASULF_RS04850
uniprot id: N0BDA7
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS08605
gene id: 387631:ASULF_RS08605
uniprot id: N0BDM8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS09010
gene id: 387631:ASULF_RS09010
uniprot id: N0BND1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

387631:ASULF RS08985
gene id: 387631:ASULF_RS08985
uniprot id: N0BNC7
names: Similarity
messages: Belongs to the SUI1 family.

387631:ASULF RS11135
gene id: 387631:ASULF_RS11135
uniprot id: N0BIS0
names: Function
names: Similarity
messages: Belongs to the MTD family.
messages: Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT(+).

387631:ASULF RS08415
gene id: 387631:ASULF_RS08415
uniprot id: N0BM66
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

387631:ASULF RS04285
gene id: 387631:ASULF_RS04285
uniprot id: N0BK42
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

387631:ASULF RS10035
gene id: 387631:ASULF_RS10035
uniprot id: N0BN45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.

387631:ASULF RS09430
gene id: 387631:ASULF_RS09430
uniprot id: N0BNK6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

387631:ASULF RS05360
gene id: 387631:ASULF_RS05360
uniprot id: N0BFP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

387631:ASULF RS08580
gene id: 387631:ASULF_RS08580
uniprot id: N0BDM1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

387631:ASULF RS03310
gene id: 387631:ASULF_RS03310
uniprot id: N0BEI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diphthine synthase family.
messages: Homodimer.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.

387631:ASULF RS08825
gene id: 387631:ASULF_RS08825
uniprot id: N0BDS6
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

387631:ASULF RS10320
gene id: 387631:ASULF_RS10320
uniprot id: N0BP08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. CofH family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated synthesis of 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.
messages: The FO synthase complex consists of two subunits, CofG and CofH.

387631:ASULF RS11105
gene id: 387631:ASULF_RS11105
uniprot id: N0BNI4
names: Caution
names: Function
names: Similarity
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02960
gene id: 387631:ASULF_RS02960
uniprot id: N0BAI5
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

387631:ASULF RS06310
gene id: 387631:ASULF_RS06310
uniprot id: N0BE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

387631:ASULF RS00615
gene id: 387631:ASULF_RS00615
uniprot id: N0BD37
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

387631:ASULF RS01000
gene id: 387631:ASULF_RS01000
uniprot id: N0BID8
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
messages: Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds via a cis-phosphoenolate intermediate.

387631:ASULF RS07830
gene id: 387631:ASULF_RS07830
uniprot id: N0BEZ6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS11000
gene id: 387631:ASULF_RS11000
uniprot id: N0BNH0
names: Function
names: Subunit
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.

387631:ASULF RS06290
gene id: 387631:ASULF_RS06290
uniprot id: N0BLY4
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

387631:ASULF RS03710
gene id: 387631:ASULF_RS03710
uniprot id: N0BJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSL4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. Interacts with DnaG.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.

387631:ASULF RS01680
gene id: 387631:ASULF_RS01680
uniprot id: N0BDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS05940
gene id: 387631:ASULF_RS05940
uniprot id: N0BC51
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Heterooligomer of catalytic and regulatory chains.

387631:ASULF RS11160
gene id: 387631:ASULF_RS11160
uniprot id: N0BIS5
names: Similarity
messages: Belongs to the UPF0284 family.

387631:ASULF RS00545
gene id: 387631:ASULF_RS00545
uniprot id: N0BAW9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS03480
gene id: 387631:ASULF_RS03480
uniprot id: N0BJP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

387631:ASULF RS02905
gene id: 387631:ASULF_RS02905
uniprot id: N0BKB8
names: Similarity
messages: Belongs to the AOR/FOR family.

387631:ASULF RS07545
gene id: 387631:ASULF_RS07545
uniprot id: N0BD50
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

387631:ASULF RS00360
gene id: 387631:ASULF_RS00360
uniprot id: N0BCZ9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

387631:ASULF RS07000
gene id: 387631:ASULF_RS07000
uniprot id: N0BMB7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

387631:ASULF RS03470
gene id: 387631:ASULF_RS03470
uniprot id: N0BAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.
messages: Part of the RNA polymerase complex.

387631:ASULF RS09810
gene id: 387631:ASULF_RS09810
uniprot id: N0BMZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycerol-1-phosphate dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
messages: Cytoplasm

387631:ASULF RS06205
gene id: 387631:ASULF_RS06205
uniprot id: N0BE13
names: Similarity
messages: Belongs to the UPF0175 family.

387631:ASULF RS00630
gene id: 387631:ASULF_RS00630
uniprot id: N0BJ21
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

387631:ASULF RS04490
gene id: 387631:ASULF_RS04490
uniprot id: N0BF67
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10200
gene id: 387631:ASULF_RS10200
uniprot id: N0BGE1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

387631:ASULF RS05210
gene id: 387631:ASULF_RS05210
uniprot id: N0BFL9
names: Similarity
messages: Belongs to the UPF0111 family.

387631:ASULF RS05050
gene id: 387631:ASULF_RS05050
uniprot id: N0BFK0
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

387631:ASULF RS00600
gene id: 387631:ASULF_RS00600
uniprot id: N0B957
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.

387631:ASULF RS01165
gene id: 387631:ASULF_RS01165
uniprot id: N0B9I2
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS09255
gene id: 387631:ASULF_RS09255
uniprot id: N0BFR4
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

387631:ASULF RS05820
gene id: 387631:ASULF_RS05820
uniprot id: N0BDU0
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

387631:ASULF RS09645
gene id: 387631:ASULF_RS09645
uniprot id: N0BEA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

387631:ASULF RS03600
gene id: 387631:ASULF_RS03600
uniprot id: N0BJR4
names: Similarity
messages: Belongs to the thiolase-like superfamily. UPF0219 family.

387631:ASULF RS03435
gene id: 387631:ASULF_RS03435
uniprot id: N0BEL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS07610
gene id: 387631:ASULF_RS07610
uniprot id: N0BEW7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofE family.
messages: Binds 2 divalent metal cations per subunit. The ions could be magnesium and/or manganese.
messages: Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
messages: Homodimer.
messages: Monovalent cation. The ion could be potassium.

387631:ASULF RS09210
gene id: 387631:ASULF_RS09210
uniprot id: N0BE05
names: Similarity
messages: Belongs to the UPF0045 family.

387631:ASULF RS02695
gene id: 387631:ASULF_RS02695
uniprot id: N0BC55
names: Similarity
messages: Belongs to the HepT RNase toxin family.

387631:ASULF RS04290
gene id: 387631:ASULF_RS04290
uniprot id: N0BF19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

387631:ASULF RS01130
gene id: 387631:ASULF_RS01130
uniprot id: N0BDC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

387631:ASULF RS06130
gene id: 387631:ASULF_RS06130
uniprot id: N0BDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS00335
gene id: 387631:ASULF_RS00335
uniprot id: N0BCZ5
names: Similarity
messages: Belongs to the UPF0146 family.

387631:ASULF RS00975
gene id: 387631:ASULF_RS00975
uniprot id: N0BID3
names: Subunit
messages: Homodimer.

387631:ASULF RS03550
gene id: 387631:ASULF_RS03550
uniprot id: N0BAV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

387631:ASULF RS08680
gene id: 387631:ASULF_RS08680
uniprot id: N0BN73
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS11165
gene id: 387631:ASULF_RS11165
uniprot id: N0BGU3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

387631:ASULF RS10890
gene id: 387631:ASULF_RS10890
uniprot id: N0BGP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS08345
gene id: 387631:ASULF_RS08345
uniprot id: N0BHA2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

387631:ASULF RS05620
gene id: 387631:ASULF_RS05620
uniprot id: N0BDQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
messages: Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
messages: Homotetramer. Interacts with SepCysS.

387631:ASULF RS00530
gene id: 387631:ASULF_RS00530
uniprot id: N0BJ06
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10880
gene id: 387631:ASULF_RS10880
uniprot id: N0BNF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp41 subfamily.
messages: Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm

387631:ASULF RS04825
gene id: 387631:ASULF_RS04825
uniprot id: N0BDA0
names: Similarity
messages: Belongs to the SIS family. PHI subfamily.

387631:ASULF RS02130
gene id: 387631:ASULF_RS02130
uniprot id: N0BBS8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

387631:ASULF RS00170
gene id: 387631:ASULF_RS00170
uniprot id: N0BIV7
names: Similarity
messages: Belongs to the thymidylate kinase family.

387631:ASULF RS08190
gene id: 387631:ASULF_RS08190
uniprot id: N0BDE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).

387631:ASULF RS10195
gene id: 387631:ASULF_RS10195
uniprot id: N0BID9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

387631:ASULF RS10895
gene id: 387631:ASULF_RS10895
uniprot id: N0BEW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

387631:ASULF RS04255
gene id: 387631:ASULF_RS04255
uniprot id: N0BKX7
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Heterodimer composed of a glutamine amidotransferase subunit (A) and a GMP-binding subunit (B).

387631:ASULF RS09270
gene id: 387631:ASULF_RS09270
uniprot id: N0BML7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS07240
gene id: 387631:ASULF_RS07240
uniprot id: N0BGR0
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

387631:ASULF RS07800
gene id: 387631:ASULF_RS07800
uniprot id: N0BH23
names: Similarity
messages: Belongs to the FwdC/FmdC family.

387631:ASULF RS08860
gene id: 387631:ASULF_RS08860
uniprot id: N0BMD5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

387631:ASULF RS01575
gene id: 387631:ASULF_RS01575
uniprot id: N0BIP7
names: Function
names: Similarity
messages: Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.
messages: Belongs to the archease family.

387631:ASULF RS10060
gene id: 387631:ASULF_RS10060
uniprot id: N0BN51
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

387631:ASULF RS04615
gene id: 387631:ASULF_RS04615
uniprot id: N0BBF9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

387631:ASULF RS08505
gene id: 387631:ASULF_RS08505
uniprot id: N0BDK7
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS02875
gene id: 387631:ASULF_RS02875
uniprot id: N0BAH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

387631:ASULF RS08390
gene id: 387631:ASULF_RS08390
uniprot id: N0BM62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

387631:ASULF RS07590
gene id: 387631:ASULF_RS07590
uniprot id: N0BEW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

387631:ASULF RS01100
gene id: 387631:ASULF_RS01100
uniprot id: N0BIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal NMN adenylyltransferase family.
messages: Cytoplasm

387631:ASULF RS09630
gene id: 387631:ASULF_RS09630
uniprot id: N0BMV6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Because the Archaea possessing a type III RuBisCO are all anaerobic, it is most likely that only the carboxylase activity of RuBisCO, and not the competitive oxygenase activity (by which RuBP reacts with O(2) to form one molecule of 3-phosphoglycerate and one molecule of 2-phosphoglycolate), is biologically relevant in these strains.
messages: Belongs to the RuBisCO large chain family. Type III subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
messages: Homodimer or homodecamer. In contrast to form I RuBisCO, the form III RuBisCO is composed solely of large subunits.

387631:ASULF RS08075
gene id: 387631:ASULF_RS08075
uniprot id: N0BH61
names: Caution
names: Function
names: Similarity
messages: Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
messages: Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS08195
gene id: 387631:ASULF_RS08195
uniprot id: N0BMZ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

387631:ASULF RS05555
gene id: 387631:ASULF_RS05555
uniprot id: N0BLM5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

387631:ASULF RS07215
gene id: 387631:ASULF_RS07215
uniprot id: N0BGQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
messages: Homodimer.
messages: Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.

387631:ASULF RS00770
gene id: 387631:ASULF_RS00770
uniprot id: N0BI97
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

387631:ASULF RS02590
gene id: 387631:ASULF_RS02590
uniprot id: N0BC38
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

387631:ASULF RS04470
gene id: 387631:ASULF_RS04470
uniprot id: N0BD15
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

387631:ASULF RS01275
gene id: 387631:ASULF_RS01275
uniprot id: N0BIJ0
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.

387631:ASULF RS07920
gene id: 387631:ASULF_RS07920
uniprot id: N0BH39
names: Cofactor
names: Similarity
messages: Belongs to the PdaD family.
messages: Binds 1 pyruvoyl group covalently per subunit.

387631:ASULF RS09115
gene id: 387631:ASULF_RS09115
uniprot id: N0BNF0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS02965
gene id: 387631:ASULF_RS02965
uniprot id: N0BKC9
names: Similarity
messages: Belongs to the MtrH family.

387631:ASULF RS01220
gene id: 387631:ASULF_RS01220
uniprot id: N0BJE0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

387631:ASULF RS03650
gene id: 387631:ASULF_RS03650
uniprot id: N0BJS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

387631:ASULF RS06145
gene id: 387631:ASULF_RS06145
uniprot id: N0BL25
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

387631:ASULF RS01740
gene id: 387631:ASULF_RS01740
uniprot id: N0BDR4
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

387631:ASULF RS07950
gene id: 387631:ASULF_RS07950
uniprot id: N0BF11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm
messages: Homotetramer.

387631:ASULF RS07230
gene id: 387631:ASULF_RS07230
uniprot id: N0BMH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

387631:ASULF RS03060
gene id: 387631:ASULF_RS03060
uniprot id: N0BCC0
names: Similarity
messages: Belongs to the UPF0173 family.

387631:ASULF RS01670
gene id: 387631:ASULF_RS01670
uniprot id: N0BJP3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TFE family.
messages: Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.
messages: The winged helix domain is involved in binding to DNA in the preinitiation complex.
messages: Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.

387631:ASULF RS00635
gene id: 387631:ASULF_RS00635
uniprot id: N0BI81
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

387631:ASULF RS03840
gene id: 387631:ASULF_RS03840
uniprot id: N0BET4
names: Similarity
messages: Belongs to the UPF0047 family.

387631:ASULF RS01345
gene id: 387631:ASULF_RS01345
uniprot id: N0BJG9
names: Function
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA.

387631:ASULF RS10570
gene id: 387631:ASULF_RS10570
uniprot id: N0BNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

387631:ASULF RS03640
gene id: 387631:ASULF_RS03640
uniprot id: N0BAW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

387631:ASULF RS00625
gene id: 387631:ASULF_RS00625
uniprot id: N0B962
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

387631:ASULF RS09025
gene id: 387631:ASULF_RS09025
uniprot id: N0BFL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

387631:ASULF RS00555
gene id: 387631:ASULF_RS00555
uniprot id: N0BJ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

387631:ASULF RS05090
gene id: 387631:ASULF_RS05090
uniprot id: N0BKK8
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS09560
gene id: 387631:ASULF_RS09560
uniprot id: N0BI09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

387631:ASULF RS11180
gene id: 387631:ASULF_RS11180
uniprot id: N0BNJ6
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS00195
gene id: 387631:ASULF_RS00195
uniprot id: N0BIW0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

387631:ASULF RS01115
gene id: 387631:ASULF_RS01115
uniprot id: N0B9H2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS00300
gene id: 387631:ASULF_RS00300
uniprot id: N0BI29
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.

387631:ASULF RS02840
gene id: 387631:ASULF_RS02840
uniprot id: N0BEC4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.
messages: Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.

387631:ASULF RS02710
gene id: 387631:ASULF_RS02710
uniprot id: N0BJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

387631:ASULF RS05735
gene id: 387631:ASULF_RS05735
uniprot id: N0BC05
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS11235
gene id: 387631:ASULF_RS11235
uniprot id: N0BIT8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FBP aldolase/phosphatase family.
messages: Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
messages: Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.
messages: Homooctamer; dimer of tetramers.

387631:ASULF RS01650
gene id: 387631:ASULF_RS01650
uniprot id: N0BIR0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS04560
gene id: 387631:ASULF_RS04560
uniprot id: N0BD31
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS00945
gene id: 387631:ASULF_RS00945
uniprot id: N0BIC8
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS03130
gene id: 387631:ASULF_RS03130
uniprot id: N0BJJ5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

387631:ASULF RS04220
gene id: 387631:ASULF_RS04220
uniprot id: N0BB75
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS05880
gene id: 387631:ASULF_RS05880
uniprot id: N0BFW4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

387631:ASULF RS04605
gene id: 387631:ASULF_RS04605
uniprot id: N0BF91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS03090
gene id: 387631:ASULF_RS03090
uniprot id: N0BAK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: Binds 1 [3Fe-4S] cluster.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

387631:ASULF RS00645
gene id: 387631:ASULF_RS00645
uniprot id: N0BAY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

387631:ASULF RS03725
gene id: 387631:ASULF_RS03725
uniprot id: N0BAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal histone HMF family.
messages: Chromosome
messages: Cytoplasm

387631:ASULF RS02790
gene id: 387631:ASULF_RS02790
uniprot id: N0BEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm

387631:ASULF RS09685
gene id: 387631:ASULF_RS09685
uniprot id: N0BI36
names: Function
names: Similarity
messages: Belongs to the TFIIB family.
messages: Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).

387631:ASULF RS01190
gene id: 387631:ASULF_RS01190
uniprot id: N0B9I8
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

387631:ASULF RS03320
gene id: 387631:ASULF_RS03320
uniprot id: N0BAQ1
names: Similarity
messages: Belongs to the glutaredoxin family.

387631:ASULF RS03195
gene id: 387631:ASULF_RS03195
uniprot id: N0BKG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

387631:ASULF RS07780
gene id: 387631:ASULF_RS07780
uniprot id: N0BEY9
names: Similarity
messages: Belongs to the UPF0282 family.

387631:ASULF RS00715
gene id: 387631:ASULF_RS00715
uniprot id: N0BD57
names: Similarity
messages: Belongs to the UPF0107 family.

387631:ASULF RS06055
gene id: 387631:ASULF_RS06055
uniprot id: N0BFZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CofD family.
messages: Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02080
gene id: 387631:ASULF_RS02080
uniprot id: N0BBR5
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS07695
gene id: 387631:ASULF_RS07695
uniprot id: N0BMS5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS09345
gene id: 387631:ASULF_RS09345
uniprot id: N0BHV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

387631:ASULF RS08675
gene id: 387631:ASULF_RS08675
uniprot id: N0BDP3
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS06375
gene id: 387631:ASULF_RS06375
uniprot id: N0BL67
names: Similarity
messages: Belongs to the acylphosphatase family.

387631:ASULF RS07660
gene id: 387631:ASULF_RS07660
uniprot id: N0BEX4
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

387631:ASULF RS01425
gene id: 387631:ASULF_RS01425
uniprot id: N0BIL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

387631:ASULF RS09215
gene id: 387631:ASULF_RS09215
uniprot id: N0BNG7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS11035
gene id: 387631:ASULF_RS11035
uniprot id: N0BGS6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.

387631:ASULF RS00355
gene id: 387631:ASULF_RS00355
uniprot id: N0BI37
names: Function
names: Similarity
messages: Belongs to the eIF-6 family.
messages: Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.

387631:ASULF RS00680
gene id: 387631:ASULF_RS00680
uniprot id: N0BJ29
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS10885
gene id: 387631:ASULF_RS10885
uniprot id: N0BIN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase PH family. Rrp42 subfamily.
messages: Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.

387631:ASULF RS10275
gene id: 387631:ASULF_RS10275
uniprot id: N0BIE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HdrA family.
messages: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
messages: The ferredoxin:CoB-CoM heterodisulfide reductase is composed of three subunits; HdrA, HdrB and HdrC.

387631:ASULF RS09535
gene id: 387631:ASULF_RS09535
uniprot id: N0BI03
names: Similarity
messages: Belongs to the arsA ATPase family.

387631:ASULF RS06045
gene id: 387631:ASULF_RS06045
uniprot id: N0BLU3
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS11320
gene id: 387631:ASULF_RS11320
uniprot id: N0BCF7
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

387631:ASULF RS07025
gene id: 387631:ASULF_RS07025
uniprot id: N0BMC3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

387631:ASULF RS01270
gene id: 387631:ASULF_RS01270
uniprot id: N0BJF2
names: Similarity
messages: Belongs to the HypE family.

387631:ASULF RS04940
gene id: 387631:ASULF_RS04940
uniprot id: N0BKI5
names: Similarity
messages: Belongs to the UPF0248 family.

387631:ASULF RS08790
gene id: 387631:ASULF_RS08790
uniprot id: N0BHI5
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS07915
gene id: 387631:ASULF_RS07915
uniprot id: N0BM00
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
messages: Binds 1 FAD per subunit.
messages: Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
messages: Reduction reaction proceeds via syn addition of hydrogen for double bonds.

387631:ASULF RS10965
gene id: 387631:ASULF_RS10965
uniprot id: N0BEX3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

387631:ASULF RS03210
gene id: 387631:ASULF_RS03210
uniprot id: N0BCE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

387631:ASULF RS00345
gene id: 387631:ASULF_RS00345
uniprot id: N0B900
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin alpha subunit family.
messages: Belongs to the prefoldin subunit alpha family.
messages: Cytoplasm
messages: Heterohexamer of two alpha and four beta subunits.
messages: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.

387631:ASULF RS01025
gene id: 387631:ASULF_RS01025
uniprot id: N0BIE3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS10765
gene id: 387631:ASULF_RS10765
uniprot id: N0BGM5
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS05635
gene id: 387631:ASULF_RS05635
uniprot id: N0BKT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Membrane

387631:ASULF RS01665
gene id: 387631:ASULF_RS01665
uniprot id: N0B9U5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

387631:ASULF RS05240
gene id: 387631:ASULF_RS05240
uniprot id: N0BDI6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

387631:ASULF RS02155
gene id: 387631:ASULF_RS02155
uniprot id: N0BBT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

387631:ASULF RS06325
gene id: 387631:ASULF_RS06325
uniprot id: N0BL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S16 family.
messages: Membrane

387631:ASULF RS06940
gene id: 387631:ASULF_RS06940
uniprot id: N0BGI2
names: Similarity
messages: Belongs to the UPF0310 family.

387631:ASULF RS01045
gene id: 387631:ASULF_RS01045
uniprot id: N0BJ96
names: Domain
names: Function
names: Similarity
messages: Belongs to the Nre family.
messages: Contains a predicted C4 metal binding domain at the N-terminus, which could be a zinc finger DNA binding domain.
messages: Involved in DNA damage repair.

387631:ASULF RS02060
gene id: 387631:ASULF_RS02060
uniprot id: N0BA25
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

387631:ASULF RS11300
gene id: 387631:ASULF_RS11300
uniprot id: N0BCZ7
names: Subunit
messages: Heterotetramer of one alpha, one beta, one delta and one gamma chain.

387631:ASULF RS02090
gene id: 387631:ASULF_RS02090
uniprot id: N0BJY6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

387631:ASULF RS05400
gene id: 387631:ASULF_RS05400
uniprot id: N0BLK7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

387631:ASULF RS00695
gene id: 387631:ASULF_RS00695
uniprot id: N0BAZ8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS02535
gene id: 387631:ASULF_RS02535
uniprot id: N0BJA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

387631:ASULF RS09795
gene id: 387631:ASULF_RS09795
uniprot id: N0BG48
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

387631:ASULF RS11100
gene id: 387631:ASULF_RS11100
uniprot id: N0BPD6
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

387631:ASULF RS00505
gene id: 387631:ASULF_RS00505
uniprot id: N0BJ03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

387631:ASULF RS01295
gene id: 387631:ASULF_RS01295
uniprot id: N0BJF8
names: Similarity
messages: Belongs to the HypD family.

387631:ASULF RS03450
gene id: 387631:ASULF_RS03450
uniprot id: N0BKJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS01885
gene id: 387631:ASULF_RS01885
uniprot id: N0BIV6
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

387631:ASULF RS00415
gene id: 387631:ASULF_RS00415
uniprot id: N0BD07
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.

387631:ASULF RS02670
gene id: 387631:ASULF_RS02670
uniprot id: N0BC50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS00535
gene id: 387631:ASULF_RS00535
uniprot id: N0BI66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

387631:ASULF RS02530
gene id: 387631:ASULF_RS02530
uniprot id: N0BK74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
messages: Heterodimer of two subunits, one of which binds GTP.

387631:ASULF RS05920
gene id: 387631:ASULF_RS05920
uniprot id: N0BLS5
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS06155
gene id: 387631:ASULF_RS06155
uniprot id: N0BE04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

387631:ASULF RS03115
gene id: 387631:ASULF_RS03115
uniprot id: N0BAL0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

387631:ASULF RS10935
gene id: 387631:ASULF_RS10935
uniprot id: N0BIN9
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS00855
gene id: 387631:ASULF_RS00855
uniprot id: N0BB28
names: Similarity
messages: Belongs to the archaeosine synthase type 1 family.

387631:ASULF RS06230
gene id: 387631:ASULF_RS06230
uniprot id: N0BE19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

387631:ASULF RS07220
gene id: 387631:ASULF_RS07220
uniprot id: N0BEM4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

387631:ASULF RS04480
gene id: 387631:ASULF_RS04480
uniprot id: N0BL22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS10725
gene id: 387631:ASULF_RS10725
uniprot id: N0BP73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane

387631:ASULF RS05595
gene id: 387631:ASULF_RS05595
uniprot id: N0BDP9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

387631:ASULF RS05800
gene id: 387631:ASULF_RS05800
uniprot id: N0BC19
names: Similarity
messages: Belongs to the HsdR family.

387631:ASULF RS10220
gene id: 387631:ASULF_RS10220
uniprot id: N0BN68
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS08610
gene id: 387631:ASULF_RS08610
uniprot id: N0BN60
names: Similarity
messages: Belongs to the citrate synthase family.

387631:ASULF RS00395
gene id: 387631:ASULF_RS00395
uniprot id: N0BAU1
names: Similarity
messages: Belongs to the activator 1 small subunits family. RfcS subfamily.

387631:ASULF RS03700
gene id: 387631:ASULF_RS03700
uniprot id: N0BAX5
names: Similarity
messages: Belongs to the UPF0215 family.

387631:ASULF RS01645
gene id: 387631:ASULF_RS01645
uniprot id: N0BJN6
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. PoK subfamily.
messages: Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.

387631:ASULF RS01825
gene id: 387631:ASULF_RS01825
uniprot id: N0B9X4
names: Function
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.

387631:ASULF RS10820
gene id: 387631:ASULF_RS10820
uniprot id: N0BEU8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

387631:ASULF RS06890
gene id: 387631:ASULF_RS06890
uniprot id: N0BLH3
names: Similarity
messages: Belongs to the UPF0310 family.

387631:ASULF RS03135
gene id: 387631:ASULF_RS03135
uniprot id: N0BEG2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

387631:ASULF RS00730
gene id: 387631:ASULF_RS00730
uniprot id: N0BB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

387631:ASULF RS10165
gene id: 387631:ASULF_RS10165
uniprot id: N0BN62
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

387631:ASULF RS10700
gene id: 387631:ASULF_RS10700
uniprot id: N0BP68
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.

387631:ASULF RS08720
gene id: 387631:ASULF_RS08720
uniprot id: N0BFG0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

387631:ASULF RS09815
gene id: 387631:ASULF_RS09815
uniprot id: N0BI67
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

387631:ASULF RS01150
gene id: 387631:ASULF_RS01150
uniprot id: N0BIG8
names: Similarity
messages: Belongs to the thymidylate kinase family.

387631:ASULF RS05305
gene id: 387631:ASULF_RS05305
uniprot id: N0BKN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.

387631:ASULF RS09225
gene id: 387631:ASULF_RS09225
uniprot id: N0BMK5
names: Similarity
messages: Belongs to the UPF0047 family.

387631:ASULF RS10480
gene id: 387631:ASULF_RS10480
uniprot id: N0BEP8
names: Similarity
messages: Belongs to the GARS family.

387631:ASULF RS06150
gene id: 387631:ASULF_RS06150
uniprot id: N0BG15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

387631:ASULF RS01380
gene id: 387631:ASULF_RS01380
uniprot id: N0BDH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

387631:ASULF RS09870
gene id: 387631:ASULF_RS09870
uniprot id: N0BI82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CdhB family.
messages: Heterotetramer of two alpha and two epsilon subunits. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta subunits with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.

387631:ASULF RS11015
gene id: 387631:ASULF_RS11015
uniprot id: N0BEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Cytoplasm
messages: Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
messages: Part of the 50S ribosomal subunit. Probably part of the RNase P complex.

387631:ASULF RS07570
gene id: 387631:ASULF_RS07570
uniprot id: N0BD54
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

387631:ASULF RS04995
gene id: 387631:ASULF_RS04995
uniprot id: N0BFJ2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS08755
gene id: 387631:ASULF_RS08755
uniprot id: N0BN86
names: Similarity
messages: Belongs to the complex I subunit 3 family.

387631:ASULF RS09825
gene id: 387631:ASULF_RS09825
uniprot id: N0BEE5
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS02070
gene id: 387631:ASULF_RS02070
uniprot id: N0BIZ6
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.

387631:ASULF RS00690
gene id: 387631:ASULF_RS00690
uniprot id: N0BD52
names: Similarity
messages: Belongs to the DMRL synthase family.

387631:ASULF RS05435
gene id: 387631:ASULF_RS05435
uniprot id: N0BFQ0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

387631:ASULF RS07030
gene id: 387631:ASULF_RS07030
uniprot id: N0BLK5
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

387631:ASULF RS07925
gene id: 387631:ASULF_RS07925
uniprot id: N0BF09
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS07990
gene id: 387631:ASULF_RS07990
uniprot id: N0BM09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

387631:ASULF RS06165
gene id: 387631:ASULF_RS06165
uniprot id: N0BLW3
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

387631:ASULF RS06665
gene id: 387631:ASULF_RS06665
uniprot id: N0BM50
names: Similarity
messages: Belongs to the Nth/MutY family.

387631:ASULF RS11215
gene id: 387631:ASULF_RS11215
uniprot id: N0BGV4
names: Similarity
messages: Belongs to the UPF0175 family.

387631:ASULF RS02810
gene id: 387631:ASULF_RS02810
uniprot id: N0BJE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

387631:ASULF RS02525
gene id: 387631:ASULF_RS02525
uniprot id: N0BAB8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS03825
gene id: 387631:ASULF_RS03825
uniprot id: N0BB00
names: Similarity
names: Subunit
messages: Belongs to the HTP reductase family.
messages: Homodimer.

387631:ASULF RS06395
gene id: 387631:ASULF_RS06395
uniprot id: N0BM02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SPT5 family.
messages: Belongs to the archaeal Spt5 family.
messages: Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).
messages: Stimulates transcription elongation.

387631:ASULF RS01310
gene id: 387631:ASULF_RS01310
uniprot id: N0BBA6
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS02290
gene id: 387631:ASULF_RS02290
uniprot id: N0BK31
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10710
gene id: 387631:ASULF_RS10710
uniprot id: N0BIK6
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

387631:ASULF RS04840
gene id: 387631:ASULF_RS04840
uniprot id: N0BKF7
names: Function
names: Similarity
messages: Belongs to the archaeal-type DHQ synthase family.
messages: Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis.

387631:ASULF RS06660
gene id: 387631:ASULF_RS06660
uniprot id: N0BCK5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

387631:ASULF RS09165
gene id: 387631:ASULF_RS09165
uniprot id: N0BNF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS12280
gene id: 387631:ASULF_RS12280
uniprot id: N0BKF1
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS11155
gene id: 387631:ASULF_RS11155
uniprot id: N0BNJ2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

387631:ASULF RS03830
gene id: 387631:ASULF_RS03830
uniprot id: N0BKP7
names: Subcellular Location Annotation
messages: Cell membrane

387631:ASULF RS02350
gene id: 387631:ASULF_RS02350
uniprot id: N0BE63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02800
gene id: 387631:ASULF_RS02800
uniprot id: N0BAG0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

387631:ASULF RS04930
gene id: 387631:ASULF_RS04930
uniprot id: N0BBN4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

387631:ASULF RS01890
gene id: 387631:ASULF_RS01890
uniprot id: N0BDV1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS02375
gene id: 387631:ASULF_RS02375
uniprot id: N0BE69
names: Subcellular Location Annotation
messages: Cell membrane

387631:ASULF RS04140
gene id: 387631:ASULF_RS04140
uniprot id: N0BCV1
names: Similarity
messages: Belongs to the thioesterase PaaI family.

387631:ASULF RS00580
gene id: 387631:ASULF_RS00580
uniprot id: N0BJ13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS05970
gene id: 387631:ASULF_RS05970
uniprot id: N0BLT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

387631:ASULF RS11025
gene id: 387631:ASULF_RS11025
uniprot id: N0BNH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.

387631:ASULF RS02085
gene id: 387631:ASULF_RS02085
uniprot id: N0BA31
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

387631:ASULF RS04555
gene id: 387631:ASULF_RS04555
uniprot id: N0BF79
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

387631:ASULF RS03075
gene id: 387631:ASULF_RS03075
uniprot id: N0BJI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

387631:ASULF RS10150
gene id: 387631:ASULF_RS10150
uniprot id: N0BEK0
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

387631:ASULF RS07725
gene id: 387631:ASULF_RS07725
uniprot id: N0BLX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

387631:ASULF RS05980
gene id: 387631:ASULF_RS05980
uniprot id: N0BC60
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

387631:ASULF RS00435
gene id: 387631:ASULF_RS00435
uniprot id: N0BI48
names: Function
names: Similarity
messages: Belongs to the GTP-dependent DPCK family.
messages: Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).

387631:ASULF RS10105
gene id: 387631:ASULF_RS10105
uniprot id: N0BNY1
names: Similarity
messages: Belongs to the P(II) protein family.

387631:ASULF RS03510
gene id: 387631:ASULF_RS03510
uniprot id: N0BJQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

387631:ASULF RS02770
gene id: 387631:ASULF_RS02770
uniprot id: N0BC69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
messages: Homodimer.

387631:ASULF RS09915
gene id: 387631:ASULF_RS09915
uniprot id: N0BN28
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

387631:ASULF RS00370
gene id: 387631:ASULF_RS00370
uniprot id: N0B906
names: Similarity
messages: Belongs to the PDCD5 family.

387631:ASULF RS07930
gene id: 387631:ASULF_RS07930
uniprot id: N0BDB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

387631:ASULF RS08065
gene id: 387631:ASULF_RS08065
uniprot id: N0BMX8
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

387631:ASULF RS01750
gene id: 387631:ASULF_RS01750
uniprot id: N0B9V7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS10730
gene id: 387631:ASULF_RS10730
uniprot id: N0BND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

387631:ASULF RS07965
gene id: 387631:ASULF_RS07965
uniprot id: N0BM06
names: Function
names: Similarity
messages: Belongs to the ATP-dependent DNA ligase family.
messages: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.

387631:ASULF RS10990
gene id: 387631:ASULF_RS10990
uniprot id: N0BEX6
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

387631:ASULF RS04345
gene id: 387631:ASULF_RS04345
uniprot id: N0BCZ2
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

387631:ASULF RS03455
gene id: 387631:ASULF_RS03455
uniprot id: N0BJP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Part of the 30S ribosomal subunit.
messages: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.

387631:ASULF RS00030
gene id: 387631:ASULF_RS00030
uniprot id: N0BCV0
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

387631:ASULF RS04665
gene id: 387631:ASULF_RS04665
uniprot id: N0BL65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

387631:ASULF RS09045
gene id: 387631:ASULF_RS09045
uniprot id: N0BHN9
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS05290
gene id: 387631:ASULF_RS05290
uniprot id: N0BDJ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS04830
gene id: 387631:ASULF_RS04830
uniprot id: N0BBK4
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

387631:ASULF RS08940
gene id: 387631:ASULF_RS08940
uniprot id: N0BHL7
names: Similarity
messages: Belongs to the UPF0216 family.

387631:ASULF RS02400
gene id: 387631:ASULF_RS02400
uniprot id: N0BE72
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

387631:ASULF RS03055
gene id: 387631:ASULF_RS03055
uniprot id: N0BEF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Heterotrimer composed of an alpha, a beta and a gamma chain.
messages: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

387631:ASULF RS01215
gene id: 387631:ASULF_RS01215
uniprot id: N0B9J3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

387631:ASULF RS00420
gene id: 387631:ASULF_RS00420
uniprot id: N0BAU7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer. Component of the KEOPS complex that consists of Kae1, Bud32, Cgi121 and Pcc1; the whole complex dimerizes.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

387631:ASULF RS01765
gene id: 387631:ASULF_RS01765
uniprot id: N0BDR9
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS05585
gene id: 387631:ASULF_RS05585
uniprot id: N0BKT0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS08770
gene id: 387631:ASULF_RS08770
uniprot id: N0BFG7
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

387631:ASULF RS11030
gene id: 387631:ASULF_RS11030
uniprot id: N0BIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

387631:ASULF RS10705
gene id: 387631:ASULF_RS10705
uniprot id: N0BNC8
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.

387631:ASULF RS10425
gene id: 387631:ASULF_RS10425
uniprot id: N0BEP0
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10950
gene id: 387631:ASULF_RS10950
uniprot id: N0BNG4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

387631:ASULF RS10940
gene id: 387631:ASULF_RS10940
uniprot id: N0BGQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

387631:ASULF RS01860
gene id: 387631:ASULF_RS01860
uniprot id: N0BIV0
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS02845
gene id: 387631:ASULF_RS02845
uniprot id: N0BC82
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

387631:ASULF RS01675
gene id: 387631:ASULF_RS01675
uniprot id: N0BIR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DnaG primase family.
messages: Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.

387631:ASULF RS03225
gene id: 387631:ASULF_RS03225
uniprot id: N0BJL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

387631:ASULF RS02850
gene id: 387631:ASULF_RS02850
uniprot id: N0BAG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is less well bound than the others.
messages: Part of the RNA polymerase complex. Forms a stalk with Rpo7 that extends from the main structure.

387631:ASULF RS03635
gene id: 387631:ASULF_RS03635
uniprot id: N0BCL4
names: Similarity
messages: Belongs to the HisA/HisF family.

387631:ASULF RS03230
gene id: 387631:ASULF_RS03230
uniprot id: N0BEH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the activator 1 small subunits family. RfcL subfamily.
messages: Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).
messages: Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.

387631:ASULF RS01995
gene id: 387631:ASULF_RS01995
uniprot id: N0BDX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS03865
gene id: 387631:ASULF_RS03865
uniprot id: N0BB04
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS00620
gene id: 387631:ASULF_RS00620
uniprot id: N0BAY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head.
messages: Part of the 30S ribosomal subunit.

387631:ASULF RS10825
gene id: 387631:ASULF_RS10825
uniprot id: N0BP90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

387631:ASULF RS03875
gene id: 387631:ASULF_RS03875
uniprot id: N0BJW6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.
messages: Belongs to the histone-like Alba family.
messages: Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
messages: Chromosome
messages: Cytoplasm
messages: Homotetramer.

387631:ASULF RS08125
gene id: 387631:ASULF_RS08125
uniprot id: N0BH67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

387631:ASULF RS09775
gene id: 387631:ASULF_RS09775
uniprot id: N0BED3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TOP6B family.
messages: Homodimer. Heterotetramer of two Top6A and two Top6B chains.
messages: Relaxes both positive and negative superturns and exhibits a strong decatenase activity.

387631:ASULF RS03730
gene id: 387631:ASULF_RS03730
uniprot id: N0BKM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

387631:ASULF RS00845
gene id: 387631:ASULF_RS00845
uniprot id: N0BIB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

387631:ASULF RS08405
gene id: 387631:ASULF_RS08405
uniprot id: N0BDI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase delta/II small subunit family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

387631:ASULF RS04820
gene id: 387631:ASULF_RS04820
uniprot id: N0BFE6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

387631:ASULF RS09190
gene id: 387631:ASULF_RS09190
uniprot id: N0BNG3
names: Function
names: Similarity
messages: Belongs to the eukaryotic RecA-like protein family.
messages: Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

387631:ASULF RS08815
gene id: 387631:ASULF_RS08815
uniprot id: N0BHJ0
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS10900
gene id: 387631:ASULF_RS10900
uniprot id: N0BPA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

387631:ASULF RS06180
gene id: 387631:ASULF_RS06180
uniprot id: N0BE08
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

387631:ASULF RS01925
gene id: 387631:ASULF_RS01925
uniprot id: N0BIW1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

387631:ASULF RS01065
gene id: 387631:ASULF_RS01065
uniprot id: N0B9G1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

387631:ASULF RS10475
gene id: 387631:ASULF_RS10475
uniprot id: N0BGH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Membrane

387631:ASULF RS06775
gene id: 387631:ASULF_RS06775
uniprot id: N0BGE5
names: Similarity
messages: Belongs to the UPF0310 family.

387631:ASULF RS11095
gene id: 387631:ASULF_RS11095
uniprot id: N0BGT3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS07760
gene id: 387631:ASULF_RS07760
uniprot id: N0BD84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal phosphopantothenate synthetase family.
messages: Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.
messages: Homodimer.

387631:ASULF RS09000
gene id: 387631:ASULF_RS09000
uniprot id: N0BFL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm

387631:ASULF RS09135
gene id: 387631:ASULF_RS09135
uniprot id: N0BDZ0
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS06015
gene id: 387631:ASULF_RS06015
uniprot id: N0BL06
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

387631:ASULF RS01010
gene id: 387631:ASULF_RS01010
uniprot id: N0BB55
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

387631:ASULF RS01160
gene id: 387631:ASULF_RS01160
uniprot id: N0BB81
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS00825
gene id: 387631:ASULF_RS00825
uniprot id: N0BD75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

387631:ASULF RS02650
gene id: 387631:ASULF_RS02650
uniprot id: N0BAD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm

387631:ASULF RS05030
gene id: 387631:ASULF_RS05030
uniprot id: N0BDF3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

387631:ASULF RS00350
gene id: 387631:ASULF_RS00350
uniprot id: N0BIY0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL20 family.
messages: Part of the 50S ribosomal subunit. Binds 23S rRNA.

387631:ASULF RS02335
gene id: 387631:ASULF_RS02335
uniprot id: N0BA79
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS02815
gene id: 387631:ASULF_RS02815
uniprot id: N0BEC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

387631:ASULF RS07995
gene id: 387631:ASULF_RS07995
uniprot id: N0BH50
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

387631:ASULF RS03240
gene id: 387631:ASULF_RS03240
uniprot id: N0BCF1
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS09850
gene id: 387631:ASULF_RS09850
uniprot id: N0BG65
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of delta and gamma chains. The ACDS complex is made up of alpha, epsilon, beta, gamma and delta chains with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
messages: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).

387631:ASULF RS06705
gene id: 387631:ASULF_RS06705
uniprot id: N0BEA9
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the UPF0165 family.

387631:ASULF RS07050
gene id: 387631:ASULF_RS07050
uniprot id: N0BMC9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

387631:ASULF RS05115
gene id: 387631:ASULF_RS05115
uniprot id: N0BLH2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

387631:ASULF RS05610
gene id: 387631:ASULF_RS05610
uniprot id: N0BKT4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

387631:ASULF RS01390
gene id: 387631:ASULF_RS01390
uniprot id: N0B9N2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

387631:ASULF RS02605
gene id: 387631:ASULF_RS02605
uniprot id: N0BJB5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

387631:ASULF RS09400
gene id: 387631:ASULF_RS09400
uniprot id: N0BE47
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS04270
gene id: 387631:ASULF_RS04270
uniprot id: N0BCX7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

387631:ASULF RS02685
gene id: 387631:ASULF_RS02685
uniprot id: N0BJC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

387631:ASULF RS09250
gene id: 387631:ASULF_RS09250
uniprot id: N0BML2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

387631:ASULF RS07715
gene id: 387631:ASULF_RS07715
uniprot id: N0BD77
names: Similarity
messages: Belongs to the peptidase M24B family.

387631:ASULF RS06315
gene id: 387631:ASULF_RS06315
uniprot id: N0BCD1
names: Function
messages: Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.

387631:ASULF RS09145
gene id: 387631:ASULF_RS09145
uniprot id: N0BMI8
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS09550
gene id: 387631:ASULF_RS09550
uniprot id: N0BNM9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-71 and Arg-74) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.

387631:ASULF RS08975
gene id: 387631:ASULF_RS08975
uniprot id: N0BFK4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

387631:ASULF RS03400
gene id: 387631:ASULF_RS03400
uniprot id: N0BKI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

387631:ASULF RS08715
gene id: 387631:ASULF_RS08715
uniprot id: N0BHG7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

387631:ASULF RS08635
gene id: 387631:ASULF_RS08635
uniprot id: N0BN64
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

387631:ASULF RS08035
gene id: 387631:ASULF_RS08035
uniprot id: N0BDC5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

387631:ASULF RS03440
gene id: 387631:ASULF_RS03440
uniprot id: N0BCI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

387631:ASULF RS10185
gene id: 387631:ASULF_RS10185
uniprot id: N0BNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
messages: Consists of a catalytic RNA component and at least 4-5 protein subunits.
messages: Cytoplasm
messages: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

387631:ASULF RS02940
gene id: 387631:ASULF_RS02940
uniprot id: N0BAI1
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS04185
gene id: 387631:ASULF_RS04185
uniprot id: N0BF01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Archaeal flagellum
messages: Belongs to the archaeal flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.

387631:ASULF RS06580
gene id: 387631:ASULF_RS06580
uniprot id: N0BE75
names: Similarity
messages: Belongs to the UPF0252 family.

387631:ASULF RS05040
gene id: 387631:ASULF_RS05040
uniprot id: N0BLG1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Membrane

387631:ASULF RS00915
gene id: 387631:ASULF_RS00915
uniprot id: N0BJ66
names: Similarity
messages: Belongs to the AOR/FOR family.

387631:ASULF RS00850
gene id: 387631:ASULF_RS00850
uniprot id: N0BD80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the archaeosine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

387631:ASULF RS03035
gene id: 387631:ASULF_RS03035
uniprot id: N0BCB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal DNA polymerase II family.
messages: Heterodimer of a large subunit and a small subunit.
messages: Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.

387631:ASULF RS03775
gene id: 387631:ASULF_RS03775
uniprot id: N0BAY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

387631:ASULF RS05300
gene id: 387631:ASULF_RS05300
uniprot id: N0BLJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

387631:ASULF RS07905
gene id: 387631:ASULF_RS07905
uniprot id: N0BDA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

387631:ASULF RS02555
gene id: 387631:ASULF_RS02555
uniprot id: N0BJA8
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

387631:ASULF RS00820
gene id: 387631:ASULF_RS00820
uniprot id: N0BIA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS01435
gene id: 387631:ASULF_RS01435
uniprot id: N0BBD4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

387631:ASULF RS07045
gene id: 387631:ASULF_RS07045
uniprot id: N0BCT5
names: Function
names: Similarity
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in regulation of DNA replication.

387631:ASULF RS10375
gene id: 387631:ASULF_RS10375
uniprot id: N0BEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS01810
gene id: 387631:ASULF_RS01810
uniprot id: N0BJS2
names: Similarity
messages: Belongs to the MEMO1 family.

387631:ASULF RS08775
gene id: 387631:ASULF_RS08775
uniprot id: N0BDR5
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS01290
gene id: 387631:ASULF_RS01290
uniprot id: N0B9L0
names: Similarity
messages: Belongs to the HupF/HypC family.

387631:ASULF RS02995
gene id: 387631:ASULF_RS02995
uniprot id: N0BJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

387631:ASULF RS04330
gene id: 387631:ASULF_RS04330
uniprot id: N0BKZ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal FAD synthase family.
messages: Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS07320
gene id: 387631:ASULF_RS07320
uniprot id: N0BGT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.
messages: Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
messages: Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.

387631:ASULF RS07195
gene id: 387631:ASULF_RS07195
uniprot id: N0BEL8
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS01795
gene id: 387631:ASULF_RS01795
uniprot id: N0BDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

387631:ASULF RS10875
gene id: 387631:ASULF_RS10875
uniprot id: N0BP98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP4 family.
messages: Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.
messages: Cytoplasm
messages: Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.

387631:ASULF RS10350
gene id: 387631:ASULF_RS10350
uniprot id: N0BEM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

387631:ASULF RS09975
gene id: 387631:ASULF_RS09975
uniprot id: N0BN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

387631:ASULF RS04635
gene id: 387631:ASULF_RS04635
uniprot id: N0BBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS11230
gene id: 387631:ASULF_RS11230
uniprot id: N0BNK3
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

387631:ASULF RS03270
gene id: 387631:ASULF_RS03270
uniprot id: N0BAP1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

387631:ASULF RS08480
gene id: 387631:ASULF_RS08480
uniprot id: N0BDK3
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS03355
gene id: 387631:ASULF_RS03355
uniprot id: N0BJM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

387631:ASULF RS03190
gene id: 387631:ASULF_RS03190
uniprot id: N0BAM2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

387631:ASULF RS00590
gene id: 387631:ASULF_RS00590
uniprot id: N0BD32
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

387631:ASULF RS04945
gene id: 387631:ASULF_RS04945
uniprot id: N0BFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

387631:ASULF RS08205
gene id: 387631:ASULF_RS08205
uniprot id: N0BH80
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS03645
gene id: 387631:ASULF_RS03645
uniprot id: N0BKL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

387631:ASULF RS03705
gene id: 387631:ASULF_RS03705
uniprot id: N0BKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Cytoplasm
messages: DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Part of the RNA polymerase complex.

387631:ASULF RS01185
gene id: 387631:ASULF_RS01185
uniprot id: N0BB85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.
messages: Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.
messages: Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

387631:ASULF RS02835
gene id: 387631:ASULF_RS02835
uniprot id: N0BJE8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

387631:ASULF RS04310
gene id: 387631:ASULF_RS04310
uniprot id: N0BK48
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

387631:ASULF RS10910
gene id: 387631:ASULF_RS10910
uniprot id: N0BIN6
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

387631:ASULF RS03110
gene id: 387631:ASULF_RS03110
uniprot id: N0BCC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

387631:ASULF RS02585
gene id: 387631:ASULF_RS02585
uniprot id: N0BE94
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS00985
gene id: 387631:ASULF_RS00985
uniprot id: N0BB50
names: Cofactor
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

387631:ASULF RS04630
gene id: 387631:ASULF_RS04630
uniprot id: N0BD51
names: Similarity
messages: Belongs to the P(II) protein family.

387631:ASULF RS02055
gene id: 387631:ASULF_RS02055
uniprot id: N0BBQ8
names: Similarity
messages: Belongs to the UPF0111 family.

387631:ASULF RS03465
gene id: 387631:ASULF_RS03465
uniprot id: N0BCI8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

387631:ASULF RS00015
gene id: 387631:ASULF_RS00015
uniprot id: N0B8W2
names: Similarity
messages: Belongs to the HepT RNase toxin family.

387631:ASULF RS00965
gene id: 387631:ASULF_RS00965
uniprot id: N0B9D8
names: Similarity
messages: Belongs to the ZPR1 family.

387631:ASULF RS11090
gene id: 387631:ASULF_RS11090
uniprot id: N0BIR2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

387631:ASULF RS05540
gene id: 387631:ASULF_RS05540
uniprot id: N0BFR5
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

387631:ASULF RS10215
gene id: 387631:ASULF_RS10215
uniprot id: N0BNZ4
names: Subcellular Location Annotation
messages: Membrane

387631:ASULF RS06005
gene id: 387631:ASULF_RS06005
uniprot id: N0BC66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

387631:ASULF RS09640
gene id: 387631:ASULF_RS09640
uniprot id: N0BFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

387631:ASULF RS05405
gene id: 387631:ASULF_RS05405
uniprot id: N0BKQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

387631:ASULF RS00910
gene id: 387631:ASULF_RS00910
uniprot id: N0B9C6
names: Subcellular Location Annotation
messages: Membrane