38301:DQN65 RS02535
gene id: 38301:DQN65_RS02535
uniprot id: A0A2X4RR90
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

38301:DQN65 RS06700
gene id: 38301:DQN65_RS06700
uniprot id: A0A2X4RM89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

38301:DQN65 RS05590
gene id: 38301:DQN65_RS05590
uniprot id: A0A2X4RLI7
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08245
gene id: 38301:DQN65_RS08245
uniprot id: A0A2X4RAG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

38301:DQN65 RS11280
gene id: 38301:DQN65_RS11280
uniprot id: A0A2X4RFE0
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

38301:DQN65 RS04935
gene id: 38301:DQN65_RS04935
uniprot id: A0A2X4RR27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

38301:DQN65 RS11170
gene id: 38301:DQN65_RS11170
uniprot id: A0A2X4RX79
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11865
gene id: 38301:DQN65_RS11865
uniprot id: A0A2X4RH53
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

38301:DQN65 RS06880
gene id: 38301:DQN65_RS06880
uniprot id: A0A2X4RDJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS09940
gene id: 38301:DQN65_RS09940
uniprot id: A0A2X4RFK0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

38301:DQN65 RS06470
gene id: 38301:DQN65_RS06470
uniprot id: A0A2X4RRZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

38301:DQN65 RS02490
gene id: 38301:DQN65_RS02490
uniprot id: A0A2X4RAC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

38301:DQN65 RS04460
gene id: 38301:DQN65_RS04460
uniprot id: A0A2X4UNL0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS04385
gene id: 38301:DQN65_RS04385
uniprot id: A0A2X4RQN6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

38301:DQN65 RS11945
gene id: 38301:DQN65_RS11945
uniprot id: A0A2X4RQ68
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

38301:DQN65 RS10255
gene id: 38301:DQN65_RS10255
uniprot id: A0A376CTS9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

38301:DQN65 RS08690
gene id: 38301:DQN65_RS08690
uniprot id: A0A2X4RAP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS00125
gene id: 38301:DQN65_RS00125
uniprot id: A0A2X4R4I1
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

38301:DQN65 RS08335
gene id: 38301:DQN65_RS08335
uniprot id: A0A2X4UCV4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

38301:DQN65 RS01975
gene id: 38301:DQN65_RS01975
uniprot id: A0A2X4R989
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

38301:DQN65 RS00030
gene id: 38301:DQN65_RS00030
uniprot id: A0A2X4RL34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

38301:DQN65 RS07205
gene id: 38301:DQN65_RS07205
uniprot id: A0A2X4RV31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

38301:DQN65 RS10845
gene id: 38301:DQN65_RS10845
uniprot id: A0A2X4URY8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

38301:DQN65 RS09975
gene id: 38301:DQN65_RS09975
uniprot id: A0A2X4REK9
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04720
gene id: 38301:DQN65_RS04720
uniprot id: A0A2X4RCG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

38301:DQN65 RS07315
gene id: 38301:DQN65_RS07315
uniprot id: A0A2X4RSH6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

38301:DQN65 RS12455
gene id: 38301:DQN65_RS12455
uniprot id: A0A2X4RCV9
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06900
gene id: 38301:DQN65_RS06900
uniprot id: A0A2X4UBY9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS08565
gene id: 38301:DQN65_RS08565
uniprot id: A0A2X4REI3
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

38301:DQN65 RS04520
gene id: 38301:DQN65_RS04520
uniprot id: A0A2X4UAH4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

38301:DQN65 RS10575
gene id: 38301:DQN65_RS10575
uniprot id: A0A2X4REY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

38301:DQN65 RS06925
gene id: 38301:DQN65_RS06925
uniprot id: A0A2X4RUX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

38301:DQN65 RS04205
gene id: 38301:DQN65_RS04205
uniprot id: A0A2X4RKH7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

38301:DQN65 RS01875
gene id: 38301:DQN65_RS01875
uniprot id: A0A2X4RQL1
names: Similarity
messages: Belongs to the TPP enzyme family.

38301:DQN65 RS06535
gene id: 38301:DQN65_RS06535
uniprot id: A0A2X4UBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

38301:DQN65 RS03845
gene id: 38301:DQN65_RS03845
uniprot id: A0A2X4RAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

38301:DQN65 RS02840
gene id: 38301:DQN65_RS02840
uniprot id: A0A2X4RAK1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

38301:DQN65 RS10600
gene id: 38301:DQN65_RS10600
uniprot id: A0A0B2YPK0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

38301:DQN65 RS00515
gene id: 38301:DQN65_RS00515
uniprot id: A0A2X4R4Y3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS04945
gene id: 38301:DQN65_RS04945
uniprot id: A0A2X4UNV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

38301:DQN65 RS06380
gene id: 38301:DQN65_RS06380
uniprot id: A0A2X4UPM4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

38301:DQN65 RS06720
gene id: 38301:DQN65_RS06720
uniprot id: A0A2X4RS44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

38301:DQN65 RS11340
gene id: 38301:DQN65_RS11340
uniprot id: A0A2X4RGB6
names: Similarity
messages: Belongs to the peptidase S14 family.

38301:DQN65 RS02890
gene id: 38301:DQN65_RS02890
uniprot id: A0A2X4RRN8
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06305
gene id: 38301:DQN65_RS06305
uniprot id: A0A2X4RDG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS09205
gene id: 38301:DQN65_RS09205
uniprot id: A0A2X4RTK1
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

38301:DQN65 RS08305
gene id: 38301:DQN65_RS08305
uniprot id: A0A2X4REP4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09785
gene id: 38301:DQN65_RS09785
uniprot id: A0A2X4RNX1
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

38301:DQN65 RS02715
gene id: 38301:DQN65_RS02715
uniprot id: A0A2X4ULV5
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

38301:DQN65 RS00400
gene id: 38301:DQN65_RS00400
uniprot id: A0A2X4RLJ7
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS05550
gene id: 38301:DQN65_RS05550
uniprot id: A0A2X4RCU0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

38301:DQN65 RS07620
gene id: 38301:DQN65_RS07620
uniprot id: A0A2X4RDD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

38301:DQN65 RS04550
gene id: 38301:DQN65_RS04550
uniprot id: A0A2X4RQS2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

38301:DQN65 RS07945
gene id: 38301:DQN65_RS07945
uniprot id: A0A2X4REH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

38301:DQN65 RS10470
gene id: 38301:DQN65_RS10470
uniprot id: A0A2X4URR8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

38301:DQN65 RS04325
gene id: 38301:DQN65_RS04325
uniprot id: A0A2X4RKM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS06630
gene id: 38301:DQN65_RS06630
uniprot id: A0A2X4UPR7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

38301:DQN65 RS10100
gene id: 38301:DQN65_RS10100
uniprot id: A0A2X4RU31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS04210
gene id: 38301:DQN65_RS04210
uniprot id: A0A2X4RT73
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

38301:DQN65 RS00600
gene id: 38301:DQN65_RS00600
uniprot id: A0A2X4R508
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

38301:DQN65 RS04775
gene id: 38301:DQN65_RS04775
uniprot id: A0A2X4RTQ9
names: Similarity
messages: Belongs to the YciI family.

38301:DQN65 RS02045
gene id: 38301:DQN65_RS02045
uniprot id: A0A2X4R996
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

38301:DQN65 RS06420
gene id: 38301:DQN65_RS06420
uniprot id: A0A2X4RRY3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

38301:DQN65 RS00185
gene id: 38301:DQN65_RS00185
uniprot id: A0A2X4RP04
names: Function
names: Similarity
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

38301:DQN65 RS09425
gene id: 38301:DQN65_RS09425
uniprot id: A0A2X4UDH8
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS05740
gene id: 38301:DQN65_RS05740
uniprot id: A0A2X4RLM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS09895
gene id: 38301:DQN65_RS09895
uniprot id: A0A2X4RWI3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS02340
gene id: 38301:DQN65_RS02340
uniprot id: A0A2X4R9I9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

38301:DQN65 RS05370
gene id: 38301:DQN65_RS05370
uniprot id: A0A2X4UB25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

38301:DQN65 RS10940
gene id: 38301:DQN65_RS10940
uniprot id: A0A2X4RGJ7
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08750
gene id: 38301:DQN65_RS08750
uniprot id: A0A2X4REY3
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

38301:DQN65 RS08705
gene id: 38301:DQN65_RS08705
uniprot id: A0A2X4RVX0
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

38301:DQN65 RS08455
gene id: 38301:DQN65_RS08455
uniprot id: A0A2X4RES2
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS09915
gene id: 38301:DQN65_RS09915
uniprot id: A0A2X4URG3
names: Similarity
messages: Belongs to the PrpD family.

38301:DQN65 RS03105
gene id: 38301:DQN65_RS03105
uniprot id: A0A2X4RAV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

38301:DQN65 RS07845
gene id: 38301:DQN65_RS07845
uniprot id: A0A2X4REE6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

38301:DQN65 RS09890
gene id: 38301:DQN65_RS09890
uniprot id: A0A2X4RFI6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

38301:DQN65 RS07415
gene id: 38301:DQN65_RS07415
uniprot id: A0A2X4RSK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS12440
gene id: 38301:DQN65_RS12440
uniprot id: A0A2X4USW6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

38301:DQN65 RS01765
gene id: 38301:DQN65_RS01765
uniprot id: A0A2X4RHX3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS05965
gene id: 38301:DQN65_RS05965
uniprot id: A0A2X4RRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

38301:DQN65 RS11045
gene id: 38301:DQN65_RS11045
uniprot id: A0A2X4UEN9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

38301:DQN65 RS04230
gene id: 38301:DQN65_RS04230
uniprot id: A0A2X4RBZ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

38301:DQN65 RS08045
gene id: 38301:DQN65_RS08045
uniprot id: A0A2X4RN16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.
messages: Membrane

38301:DQN65 RS03050
gene id: 38301:DQN65_RS03050
uniprot id: A0A2X4R762
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

38301:DQN65 RS05030
gene id: 38301:DQN65_RS05030
uniprot id: A0A2X4RCJ5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

38301:DQN65 RS02175
gene id: 38301:DQN65_RS02175
uniprot id: A0A2X4ULD6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS02165
gene id: 38301:DQN65_RS02165
uniprot id: A0A2X4R9X8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

38301:DQN65 RS10625
gene id: 38301:DQN65_RS10625
uniprot id: A0A0B2YPJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

38301:DQN65 RS08405
gene id: 38301:DQN65_RS08405
uniprot id: A0A2X4REQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

38301:DQN65 RS03140
gene id: 38301:DQN65_RS03140
uniprot id: A0A2X4UMC6
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

38301:DQN65 RS10580
gene id: 38301:DQN65_RS10580
uniprot id: A0A2X4RBQ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

38301:DQN65 RS04035
gene id: 38301:DQN65_RS04035
uniprot id: A0A2X4RBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

38301:DQN65 RS10725
gene id: 38301:DQN65_RS10725
uniprot id: A0A2X4UEA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

38301:DQN65 RS05725
gene id: 38301:DQN65_RS05725
uniprot id: A0A2X4UBA1
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

38301:DQN65 RS11995
gene id: 38301:DQN65_RS11995
uniprot id: A0A2X4RQ83
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-68 and Arg-71) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

38301:DQN65 RS07625
gene id: 38301:DQN65_RS07625
uniprot id: A0A2X4RA73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

38301:DQN65 RS07540
gene id: 38301:DQN65_RS07540
uniprot id: A0A2X4RVA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

38301:DQN65 RS05700
gene id: 38301:DQN65_RS05700
uniprot id: A0A2X4RU93
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

38301:DQN65 RS04000
gene id: 38301:DQN65_RS04000
uniprot id: A0A2X4RB39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

38301:DQN65 RS09920
gene id: 38301:DQN65_RS09920
uniprot id: A0A2X4UDS6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

38301:DQN65 RS07135
gene id: 38301:DQN65_RS07135
uniprot id: A0A2X4RD28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

38301:DQN65 RS09970
gene id: 38301:DQN65_RS09970
uniprot id: A0A2X4UDT4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08085
gene id: 38301:DQN65_RS08085
uniprot id: A0A2X4UCQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

38301:DQN65 RS06600
gene id: 38301:DQN65_RS06600
uniprot id: A0A2X4RM65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

38301:DQN65 RS01450
gene id: 38301:DQN65_RS01450
uniprot id: A0A2X4R9B9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

38301:DQN65 RS10750
gene id: 38301:DQN65_RS10750
uniprot id: A0A2X4RG11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

38301:DQN65 RS01475
gene id: 38301:DQN65_RS01475
uniprot id: A0A2X4R8U1
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS01645
gene id: 38301:DQN65_RS01645
uniprot id: A0A2X4R8Y3
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

38301:DQN65 RS00890
gene id: 38301:DQN65_RS00890
uniprot id: A0A2X4R8B3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS01845
gene id: 38301:DQN65_RS01845
uniprot id: A0A2X4R9N0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

38301:DQN65 RS05470
gene id: 38301:DQN65_RS05470
uniprot id: A0A2X4UB48
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02365
gene id: 38301:DQN65_RS02365
uniprot id: A0A2X4R6H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

38301:DQN65 RS04065
gene id: 38301:DQN65_RS04065
uniprot id: A0A2X4UN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS00615
gene id: 38301:DQN65_RS00615
uniprot id: A0A2X4UK12
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07260
gene id: 38301:DQN65_RS07260
uniprot id: A0A2X4RDS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

38301:DQN65 RS07210
gene id: 38301:DQN65_RS07210
uniprot id: A0A2X4RDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

38301:DQN65 RS03990
gene id: 38301:DQN65_RS03990
uniprot id: A0A2X4RC17
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03630
gene id: 38301:DQN65_RS03630
uniprot id: A0A2X4RJW4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

38301:DQN65 RS02520
gene id: 38301:DQN65_RS02520
uniprot id: A0A2X4U8B0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

38301:DQN65 RS06645
gene id: 38301:DQN65_RS06645
uniprot id: A0A2X4R9L3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

38301:DQN65 RS02060
gene id: 38301:DQN65_RS02060
uniprot id: A0A2X4R9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

38301:DQN65 RS10095
gene id: 38301:DQN65_RS10095
uniprot id: A0A2X4RF99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

38301:DQN65 RS08840
gene id: 38301:DQN65_RS08840
uniprot id: A0A2X4RF76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

38301:DQN65 RS10595
gene id: 38301:DQN65_RS10595
uniprot id: A0A2X4RWW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

38301:DQN65 RS12425
gene id: 38301:DQN65_RS12425
uniprot id: A0A2X4RGI9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

38301:DQN65 RS01955
gene id: 38301:DQN65_RS01955
uniprot id: A0A2X4R962
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

38301:DQN65 RS05530
gene id: 38301:DQN65_RS05530
uniprot id: A0A2X4R928
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS11230
gene id: 38301:DQN65_RS11230
uniprot id: A0A2X4RGR0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

38301:DQN65 RS10540
gene id: 38301:DQN65_RS10540
uniprot id: A0A2X4RFX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

38301:DQN65 RS03765
gene id: 38301:DQN65_RS03765
uniprot id: A0A2X4UMY6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

38301:DQN65 RS06970
gene id: 38301:DQN65_RS06970
uniprot id: A0A2X4RDL0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

38301:DQN65 RS10915
gene id: 38301:DQN65_RS10915
uniprot id: A0A2X4RPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

38301:DQN65 RS00740
gene id: 38301:DQN65_RS00740
uniprot id: A0A2X4R859
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

38301:DQN65 RS01965
gene id: 38301:DQN65_RS01965
uniprot id: A0A2X4RMX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

38301:DQN65 RS05215
gene id: 38301:DQN65_RS05215
uniprot id: A0A2X4RTZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

38301:DQN65 RS02915
gene id: 38301:DQN65_RS02915
uniprot id: A0A2X4RRP9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

38301:DQN65 RS04330
gene id: 38301:DQN65_RS04330
uniprot id: A0A2X4RTC8
names: Similarity
messages: Belongs to the acylphosphatase family.

38301:DQN65 RS09405
gene id: 38301:DQN65_RS09405
uniprot id: A0A2X4REW9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

38301:DQN65 RS11650
gene id: 38301:DQN65_RS11650
uniprot id: A0A2X4RV19
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

38301:DQN65 RS11300
gene id: 38301:DQN65_RS11300
uniprot id: A0A2X4RFW8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

38301:DQN65 RS09555
gene id: 38301:DQN65_RS09555
uniprot id: A0A2X4RTR2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07755
gene id: 38301:DQN65_RS07755
uniprot id: A0A2X4RE33
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

38301:DQN65 RS04410
gene id: 38301:DQN65_RS04410
uniprot id: A0A2X4RC54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

38301:DQN65 RS01615
gene id: 38301:DQN65_RS01615
uniprot id: A0A2X4UKV1
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

38301:DQN65 RS11250
gene id: 38301:DQN65_RS11250
uniprot id: A0A2X4RG91
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

38301:DQN65 RS02760
gene id: 38301:DQN65_RS02760
uniprot id: A0A2X4RAH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

38301:DQN65 RS10745
gene id: 38301:DQN65_RS10745
uniprot id: A0A2X4RPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

38301:DQN65 RS00530
gene id: 38301:DQN65_RS00530
uniprot id: A0A2X4RPD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02355
gene id: 38301:DQN65_RS02355
uniprot id: A0A2X4RA78
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

38301:DQN65 RS07510
gene id: 38301:DQN65_RS07510
uniprot id: A0A2X4REF3
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

38301:DQN65 RS10310
gene id: 38301:DQN65_RS10310
uniprot id: A0A2X4RG05
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

38301:DQN65 RS04660
gene id: 38301:DQN65_RS04660
uniprot id: A0A2X4RKY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

38301:DQN65 RS12230
gene id: 38301:DQN65_RS12230
uniprot id: A0A2X4RHC6
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09735
gene id: 38301:DQN65_RS09735
uniprot id: A0A2X4RNV8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

38301:DQN65 RS03285
gene id: 38301:DQN65_RS03285
uniprot id: A0A2X4RBA0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

38301:DQN65 RS03750
gene id: 38301:DQN65_RS03750
uniprot id: A0A2X4RJY2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06690
gene id: 38301:DQN65_RS06690
uniprot id: A0A2X4RCU4
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

38301:DQN65 RS04415
gene id: 38301:DQN65_RS04415
uniprot id: A0A2X4RCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

38301:DQN65 RS04160
gene id: 38301:DQN65_RS04160
uniprot id: A0A2X4RBX0
names: Similarity
messages: Belongs to the HSP15 family.

38301:DQN65 RS01060
gene id: 38301:DQN65_RS01060
uniprot id: A0A2X4R940
names: Similarity
messages: Belongs to the universal stress protein A family.

38301:DQN65 RS05730
gene id: 38301:DQN65_RS05730
uniprot id: A0A2X4RCA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

38301:DQN65 RS06840
gene id: 38301:DQN65_RS06840
uniprot id: A0A2X4RDZ3
names: Similarity
messages: Belongs to the isochorismate synthase family.

38301:DQN65 RS04645
gene id: 38301:DQN65_RS04645
uniprot id: A0A2X4UAM9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS04570
gene id: 38301:DQN65_RS04570
uniprot id: A0A2X4RBM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS11070
gene id: 38301:DQN65_RS11070
uniprot id: A0A2X4RX60
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

38301:DQN65 RS09980
gene id: 38301:DQN65_RS09980
uniprot id: A0A2X4RBC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS11025
gene id: 38301:DQN65_RS11025
uniprot id: A0A2X4RFQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

38301:DQN65 RS11030
gene id: 38301:DQN65_RS11030
uniprot id: A0A2X4RUL7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS10445
gene id: 38301:DQN65_RS10445
uniprot id: A0A2X4RFV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

38301:DQN65 RS03150
gene id: 38301:DQN65_RS03150
uniprot id: A0A2X4R7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS08225
gene id: 38301:DQN65_RS08225
uniprot id: A0A2X4REV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS06240
gene id: 38301:DQN65_RS06240
uniprot id: A0A2X4R9E1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

38301:DQN65 RS05695
gene id: 38301:DQN65_RS05695
uniprot id: A0A2X4RD21
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

38301:DQN65 RS01240
gene id: 38301:DQN65_RS01240
uniprot id: A0A2X4RHG5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

38301:DQN65 RS09500
gene id: 38301:DQN65_RS09500
uniprot id: A0A2X4RWA6
names: Function
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

38301:DQN65 RS06500
gene id: 38301:DQN65_RS06500
uniprot id: A0A2X4RM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

38301:DQN65 RS05525
gene id: 38301:DQN65_RS05525
uniprot id: A0A2X4RC65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS00200
gene id: 38301:DQN65_RS00200
uniprot id: A0A2X4U5Y1
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

38301:DQN65 RS01120
gene id: 38301:DQN65_RS01120
uniprot id: A0A2X4UKH4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

38301:DQN65 RS07665
gene id: 38301:DQN65_RS07665
uniprot id: A0A2X4UCI0
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

38301:DQN65 RS09710
gene id: 38301:DQN65_RS09710
uniprot id: A0A2X4RFM8
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

38301:DQN65 RS01310
gene id: 38301:DQN65_RS01310
uniprot id: A0A2X4R991
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

38301:DQN65 RS02240
gene id: 38301:DQN65_RS02240
uniprot id: A0A0B2YWY0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

38301:DQN65 RS01010
gene id: 38301:DQN65_RS01010
uniprot id: A0A2X4R900
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS01175
gene id: 38301:DQN65_RS01175
uniprot id: A0A2X4R5H8
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07280
gene id: 38301:DQN65_RS07280
uniprot id: A0A2X4UC86
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

38301:DQN65 RS03115
gene id: 38301:DQN65_RS03115
uniprot id: A0A2X4UMB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS04980
gene id: 38301:DQN65_RS04980
uniprot id: A0A2X4RCI7
names: Function
names: Similarity
names: Subunit
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.
messages: Homotrimer.

38301:DQN65 RS10505
gene id: 38301:DQN65_RS10505
uniprot id: A0A2X4RUB4
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

38301:DQN65 RS07850
gene id: 38301:DQN65_RS07850
uniprot id: A0A2X4RVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

38301:DQN65 RS10610
gene id: 38301:DQN65_RS10610
uniprot id: A0A2X4RG78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

38301:DQN65 RS03805
gene id: 38301:DQN65_RS03805
uniprot id: A0A2X4RBG7
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

38301:DQN65 RS10475
gene id: 38301:DQN65_RS10475
uniprot id: A0A2X4UE56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

38301:DQN65 RS05180
gene id: 38301:DQN65_RS05180
uniprot id: A0A2X4RD04
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

38301:DQN65 RS06495
gene id: 38301:DQN65_RS06495
uniprot id: A0A2X4R9I1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

38301:DQN65 RS06275
gene id: 38301:DQN65_RS06275
uniprot id: A0A2X4UPK3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

38301:DQN65 RS10265
gene id: 38301:DQN65_RS10265
uniprot id: A0A2X4URN0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

38301:DQN65 RS09075
gene id: 38301:DQN65_RS09075
uniprot id: A0A2X4RE44
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

38301:DQN65 RS05035
gene id: 38301:DQN65_RS05035
uniprot id: A0A2X4RR49
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS04810
gene id: 38301:DQN65_RS04810
uniprot id: A0A2X4R8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

38301:DQN65 RS06865
gene id: 38301:DQN65_RS06865
uniprot id: A0A2X4RMC2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

38301:DQN65 RS01190
gene id: 38301:DQN65_RS01190
uniprot id: A0A2X4R958
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

38301:DQN65 RS00635
gene id: 38301:DQN65_RS00635
uniprot id: A0A2X4UK20
names: Similarity
messages: Belongs to the PspA/IM30 family.

38301:DQN65 RS06545
gene id: 38301:DQN65_RS06545
uniprot id: A0A2X4R9J2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

38301:DQN65 RS00775
gene id: 38301:DQN65_RS00775
uniprot id: A0A2X4RPN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

38301:DQN65 RS10560
gene id: 38301:DQN65_RS10560
uniprot id: A0A2X4RG70
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

38301:DQN65 RS01295
gene id: 38301:DQN65_RS01295
uniprot id: A0A2X4RQ48
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS01420
gene id: 38301:DQN65_RS01420
uniprot id: A0A2X4U783
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08845
gene id: 38301:DQN65_RS08845
uniprot id: A0A2X4UQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

38301:DQN65 RS08160
gene id: 38301:DQN65_RS08160
uniprot id: A0A2X4RVM2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

38301:DQN65 RS10795
gene id: 38301:DQN65_RS10795
uniprot id: A0A2X4RPG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

38301:DQN65 RS09070
gene id: 38301:DQN65_RS09070
uniprot id: A0A2X4UDB9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

38301:DQN65 RS01470
gene id: 38301:DQN65_RS01470
uniprot id: A0A2X4U794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS06740
gene id: 38301:DQN65_RS06740
uniprot id: A0A2X4RCV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

38301:DQN65 RS07190
gene id: 38301:DQN65_RS07190
uniprot id: A0A2X4R9W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

38301:DQN65 RS02710
gene id: 38301:DQN65_RS02710
uniprot id: A0A2X4RNJ0
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

38301:DQN65 RS00470
gene id: 38301:DQN65_RS00470
uniprot id: A0A2X4R4X2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07545
gene id: 38301:DQN65_RS07545
uniprot id: A0A2X4RDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

38301:DQN65 RS10615
gene id: 38301:DQN65_RS10615
uniprot id: A0A2X4URU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

38301:DQN65 RS07975
gene id: 38301:DQN65_RS07975
uniprot id: A0A2X4UCN3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

38301:DQN65 RS05360
gene id: 38301:DQN65_RS05360
uniprot id: A0A2X4RD45
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

38301:DQN65 RS06560
gene id: 38301:DQN65_RS06560
uniprot id: A0A2X4RUR1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

38301:DQN65 RS05630
gene id: 38301:DQN65_RS05630
uniprot id: A0A2X4RC85
names: Similarity
messages: Belongs to the universal stress protein A family.

38301:DQN65 RS05535
gene id: 38301:DQN65_RS05535
uniprot id: A0A2X4RLH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

38301:DQN65 RS06510
gene id: 38301:DQN65_RS06510
uniprot id: A0A2X4RUP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

38301:DQN65 RS02570
gene id: 38301:DQN65_RS02570
uniprot id: A0A2X4ULQ8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

38301:DQN65 RS09280
gene id: 38301:DQN65_RS09280
uniprot id: A0A2X4RAZ4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS01435
gene id: 38301:DQN65_RS01435
uniprot id: A0A2X4RHL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

38301:DQN65 RS04355
gene id: 38301:DQN65_RS04355
uniprot id: A0A2X4RC37
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08330
gene id: 38301:DQN65_RS08330
uniprot id: A0A2X4UQN0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

38301:DQN65 RS04840
gene id: 38301:DQN65_RS04840
uniprot id: A0A2X4RCT8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

38301:DQN65 RS10150
gene id: 38301:DQN65_RS10150
uniprot id: A0A2X4RU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

38301:DQN65 RS01590
gene id: 38301:DQN65_RS01590
uniprot id: A0A2X4RHQ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

38301:DQN65 RS03620
gene id: 38301:DQN65_RS03620
uniprot id: A0A2X4UMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

38301:DQN65 RS04765
gene id: 38301:DQN65_RS04765
uniprot id: A0A2X4RL25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Membrane

38301:DQN65 RS02495
gene id: 38301:DQN65_RS02495
uniprot id: A0A2X4R6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS03970
gene id: 38301:DQN65_RS03970
uniprot id: A0A2X4RBM5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS06505
gene id: 38301:DQN65_RS06505
uniprot id: A0A2X4RDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

38301:DQN65 RS01605
gene id: 38301:DQN65_RS01605
uniprot id: A0A2X4RQC3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

38301:DQN65 RS04985
gene id: 38301:DQN65_RS04985
uniprot id: A0A2X4RR39
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03975
gene id: 38301:DQN65_RS03975
uniprot id: A0A2X4RSY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

38301:DQN65 RS09510
gene id: 38301:DQN65_RS09510
uniprot id: A0A2X4RTQ2
names: Similarity
messages: Belongs to the DapA family.

38301:DQN65 RS04295
gene id: 38301:DQN65_RS04295
uniprot id: A0A2X4UAA2
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

38301:DQN65 RS04435
gene id: 38301:DQN65_RS04435
uniprot id: A0A2X4R8J4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04470
gene id: 38301:DQN65_RS04470
uniprot id: A0A2X4UAG2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

38301:DQN65 RS11450
gene id: 38301:DQN65_RS11450
uniprot id: A0A2X4RUW3
names: Subcellular Location Annotation
messages: Cytoplasm

38301:DQN65 RS00580
gene id: 38301:DQN65_RS00580
uniprot id: A0A2X4RLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

38301:DQN65 RS09455
gene id: 38301:DQN65_RS09455
uniprot id: A0A2X4REX9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

38301:DQN65 RS04900
gene id: 38301:DQN65_RS04900
uniprot id: A0A2X4UAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

38301:DQN65 RS02180
gene id: 38301:DQN65_RS02180
uniprot id: A0A2X4R9C8
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09275
gene id: 38301:DQN65_RS09275
uniprot id: A0A2X4RE81
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

38301:DQN65 RS10515
gene id: 38301:DQN65_RS10515
uniprot id: A0A2X4URS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

38301:DQN65 RS08155
gene id: 38301:DQN65_RS08155
uniprot id: A0A2X4REL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS11175
gene id: 38301:DQN65_RS11175
uniprot id: A0A2X4RFU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

38301:DQN65 RS03080
gene id: 38301:DQN65_RS03080
uniprot id: A0A2X4RNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

38301:DQN65 RS10030
gene id: 38301:DQN65_RS10030
uniprot id: A0A2X4RBE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

38301:DQN65 RS06235
gene id: 38301:DQN65_RS06235
uniprot id: A0A2X4RCK8
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

38301:DQN65 RS02730
gene id: 38301:DQN65_RS02730
uniprot id: A0A2X4RRG3
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

38301:DQN65 RS11265
gene id: 38301:DQN65_RS11265
uniprot id: A0A2X4RGS0
names: Similarity
messages: Belongs to the peptidase M1 family.

38301:DQN65 RS04605
gene id: 38301:DQN65_RS04605
uniprot id: A0A2X4RC99
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

38301:DQN65 RS10495
gene id: 38301:DQN65_RS10495
uniprot id: A0A2X4RWU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

38301:DQN65 RS04010
gene id: 38301:DQN65_RS04010
uniprot id: A0A2X4RBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

38301:DQN65 RS00815
gene id: 38301:DQN65_RS00815
uniprot id: A0A2X4RLX3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

38301:DQN65 RS06330
gene id: 38301:DQN65_RS06330
uniprot id: A0A2X4UPL2
names: Similarity
messages: Belongs to the peptidase C40 family.

38301:DQN65 RS03985
gene id: 38301:DQN65_RS03985
uniprot id: A0A2X4RQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

38301:DQN65 RS00340
gene id: 38301:DQN65_RS00340
uniprot id: A0A2X4RLG2
names: Similarity
messages: Belongs to the YjdM family.

38301:DQN65 RS02230
gene id: 38301:DQN65_RS02230
uniprot id: A0A2X4R9E3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02260
gene id: 38301:DQN65_RS02260
uniprot id: A0A2X4RIC8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

38301:DQN65 RS00510
gene id: 38301:DQN65_RS00510
uniprot id: A0A2X4R7Y2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02555
gene id: 38301:DQN65_RS02555
uniprot id: A0A2X4R9N7
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

38301:DQN65 RS08735
gene id: 38301:DQN65_RS08735
uniprot id: A0A2X4RDY9
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

38301:DQN65 RS10980
gene id: 38301:DQN65_RS10980
uniprot id: A0A2X4RFP7
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS05620
gene id: 38301:DQN65_RS05620
uniprot id: A0A2X4UP75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

38301:DQN65 RS12135
gene id: 38301:DQN65_RS12135
uniprot id: A0A2X4USQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS04905
gene id: 38301:DQN65_RS04905
uniprot id: A0A2X4RBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

38301:DQN65 RS11095
gene id: 38301:DQN65_RS11095
uniprot id: A0A2X4UEQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

38301:DQN65 RS11485
gene id: 38301:DQN65_RS11485
uniprot id: A0A2X4RGE3
names: Similarity
messages: Belongs to the GSP E family.

38301:DQN65 RS07450
gene id: 38301:DQN65_RS07450
uniprot id: A0A2X4RE62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

38301:DQN65 RS03125
gene id: 38301:DQN65_RS03125
uniprot id: A0A2X4RJA1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

38301:DQN65 RS02865
gene id: 38301:DQN65_RS02865
uniprot id: A0A376D1L5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

38301:DQN65 RS03740
gene id: 38301:DQN65_RS03740
uniprot id: A0A2X4UMX6
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02680
gene id: 38301:DQN65_RS02680
uniprot id: A0A2X4RAJ1
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

38301:DQN65 RS05885
gene id: 38301:DQN65_RS05885
uniprot id: A0A2X4R995
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

38301:DQN65 RS06325
gene id: 38301:DQN65_RS06325
uniprot id: A0A2X4RDP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS12240
gene id: 38301:DQN65_RS12240
uniprot id: A0A2X4UFH0
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

38301:DQN65 RS01220
gene id: 38301:DQN65_RS01220
uniprot id: A0A2X4RM90
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS05380
gene id: 38301:DQN65_RS05380
uniprot id: A0A2X4R902
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

38301:DQN65 RS06195
gene id: 38301:DQN65_RS06195
uniprot id: A0A2X4RLY3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

38301:DQN65 RS03695
gene id: 38301:DQN65_RS03695
uniprot id: A0A2X4RBC5
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03035
gene id: 38301:DQN65_RS03035
uniprot id: A0A2X4RAR9
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS05900
gene id: 38301:DQN65_RS05900
uniprot id: A0A2X4RUD3
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00415
gene id: 38301:DQN65_RS00415
uniprot id: A0A2X4U6B0
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

38301:DQN65 RS06585
gene id: 38301:DQN65_RS06585
uniprot id: A0A2X4UBR4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS06950
gene id: 38301:DQN65_RS06950
uniprot id: A0A2X4UC02
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

38301:DQN65 RS10530
gene id: 38301:DQN65_RS10530
uniprot id: A0A2X4RBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

38301:DQN65 RS11700
gene id: 38301:DQN65_RS11700
uniprot id: A0A2X4RV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

38301:DQN65 RS07470
gene id: 38301:DQN65_RS07470
uniprot id: A0A2X4REE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

38301:DQN65 RS01980
gene id: 38301:DQN65_RS01980
uniprot id: A0A2X4RI49
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

38301:DQN65 RS05115
gene id: 38301:DQN65_RS05115
uniprot id: A0A2X4RL94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS06225
gene id: 38301:DQN65_RS06225
uniprot id: A0A2X4UPJ2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

38301:DQN65 RS05445
gene id: 38301:DQN65_RS05445
uniprot id: A0A2X4RU38
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

38301:DQN65 RS11325
gene id: 38301:DQN65_RS11325
uniprot id: A0A2X4RFF2
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

38301:DQN65 RS10280
gene id: 38301:DQN65_RS10280
uniprot id: A0A2X4RBI6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

38301:DQN65 RS02870
gene id: 38301:DQN65_RS02870
uniprot id: A0A2X4RNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

38301:DQN65 RS11635
gene id: 38301:DQN65_RS11635
uniprot id: A0A2X4RGH9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

38301:DQN65 RS08080
gene id: 38301:DQN65_RS08080
uniprot id: A0A2X4UQI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS03950
gene id: 38301:DQN65_RS03950
uniprot id: A0A2X4UN26
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

38301:DQN65 RS10000
gene id: 38301:DQN65_RS10000
uniprot id: A0A2X4RF79
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

38301:DQN65 RS03980
gene id: 38301:DQN65_RS03980
uniprot id: A0A2X4RBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS04345
gene id: 38301:DQN65_RS04345
uniprot id: A0A2X4RKN3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

38301:DQN65 RS03860
gene id: 38301:DQN65_RS03860
uniprot id: A0A2X4RPW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

38301:DQN65 RS11555
gene id: 38301:DQN65_RS11555
uniprot id: A0A2X4RGY6
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

38301:DQN65 RS02335
gene id: 38301:DQN65_RS02335
uniprot id: A0A2X4R6F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

38301:DQN65 RS12520
gene id: 38301:DQN65_RS12520
uniprot id: A0A2X4RQJ6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

38301:DQN65 RS00080
gene id: 38301:DQN65_RS00080
uniprot id: A0A2X4UJH4
names: Similarity
messages: Belongs to the peptidase M1 family.

38301:DQN65 RS10200
gene id: 38301:DQN65_RS10200
uniprot id: A0A2X4RU49
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00175
gene id: 38301:DQN65_RS00175
uniprot id: A0A2X4U5X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

38301:DQN65 RS09445
gene id: 38301:DQN65_RS09445
uniprot id: A0A2X4RF98
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

38301:DQN65 RS12100
gene id: 38301:DQN65_RS12100
uniprot id: A0A2X4RCN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan.
messages: Belongs to the emb family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS09215
gene id: 38301:DQN65_RS09215
uniprot id: A0A2X4UR44
names: Similarity
messages: Belongs to the phosphohexose mutase family.

38301:DQN65 RS07185
gene id: 38301:DQN65_RS07185
uniprot id: A0A2X4RD38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

38301:DQN65 RS06115
gene id: 38301:DQN65_RS06115
uniprot id: A0A2X4RDL1
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

38301:DQN65 RS05880
gene id: 38301:DQN65_RS05880
uniprot id: A0A2X4RCD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

38301:DQN65 RS06920
gene id: 38301:DQN65_RS06920
uniprot id: A0A2X4RDU0
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02930
gene id: 38301:DQN65_RS02930
uniprot id: A0A2X4U8S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

38301:DQN65 RS02850
gene id: 38301:DQN65_RS02850
uniprot id: A0A2X4U8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

38301:DQN65 RS04665
gene id: 38301:DQN65_RS04665
uniprot id: A0A2X4RCE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

38301:DQN65 RS02055
gene id: 38301:DQN65_RS02055
uniprot id: A0A2X4ULA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

38301:DQN65 RS00190
gene id: 38301:DQN65_RS00190
uniprot id: A0A2X4R895
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS04245
gene id: 38301:DQN65_RS04245
uniprot id: A0A2X4UA74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

38301:DQN65 RS01455
gene id: 38301:DQN65_RS01455
uniprot id: A0A2X4RME6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

38301:DQN65 RS11960
gene id: 38301:DQN65_RS11960
uniprot id: A0A2X4RG90
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

38301:DQN65 RS07475
gene id: 38301:DQN65_RS07475
uniprot id: A0A2X4UQ66
names: Similarity
messages: Belongs to the Nudix hydrolase family.

38301:DQN65 RS09775
gene id: 38301:DQN65_RS09775
uniprot id: A0A2X4REG8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

38301:DQN65 RS09990
gene id: 38301:DQN65_RS09990
uniprot id: A0A2X4RFL0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

38301:DQN65 RS00535
gene id: 38301:DQN65_RS00535
uniprot id: A0A2X4R8P3
names: Similarity
messages: Belongs to the FPG family.

38301:DQN65 RS11595
gene id: 38301:DQN65_RS11595
uniprot id: A0A2X4RV08
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

38301:DQN65 RS06575
gene id: 38301:DQN65_RS06575
uniprot id: A0A2X4RDU4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

38301:DQN65 RS00230
gene id: 38301:DQN65_RS00230
uniprot id: A0A2X4R4L9
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03120
gene id: 38301:DQN65_RS03120
uniprot id: A0A2X4RA71
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

38301:DQN65 RS09850
gene id: 38301:DQN65_RS09850
uniprot id: A0A2X4RF53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

38301:DQN65 RS04830
gene id: 38301:DQN65_RS04830
uniprot id: A0A2X4RCF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS02235
gene id: 38301:DQN65_RS02235
uniprot id: A0A2X4RQX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

38301:DQN65 RS12530
gene id: 38301:DQN65_RS12530
uniprot id: A0A2X4RY39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

38301:DQN65 RS03315
gene id: 38301:DQN65_RS03315
uniprot id: A0A2X4U980
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11475
gene id: 38301:DQN65_RS11475
uniprot id: A0A2X4RC96
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00285
gene id: 38301:DQN65_RS00285
uniprot id: A0A2X4R7P8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS03530
gene id: 38301:DQN65_RS03530
uniprot id: A0A2X4RPJ4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

38301:DQN65 RS10820
gene id: 38301:DQN65_RS10820
uniprot id: A0A2X4RG21
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

38301:DQN65 RS00910
gene id: 38301:DQN65_RS00910
uniprot id: A0A2X4R8W9
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

38301:DQN65 RS10585
gene id: 38301:DQN65_RS10585
uniprot id: A0A2X4RPC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

38301:DQN65 RS11315
gene id: 38301:DQN65_RS11315
uniprot id: A0A2X4US82
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11245
gene id: 38301:DQN65_RS11245
uniprot id: A0A2X4RC48
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

38301:DQN65 RS09255
gene id: 38301:DQN65_RS09255
uniprot id: A0A2X4RTL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS01720
gene id: 38301:DQN65_RS01720
uniprot id: A0A2X4R9I3
names: Similarity
messages: Belongs to the Nth/MutY family.

38301:DQN65 RS10020
gene id: 38301:DQN65_RS10020
uniprot id: A0A2X4UDV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

38301:DQN65 RS01230
gene id: 38301:DQN65_RS01230
uniprot id: A0A2X4R8K5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

38301:DQN65 RS11535
gene id: 38301:DQN65_RS11535
uniprot id: A0A2X4RGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS04820
gene id: 38301:DQN65_RS04820
uniprot id: A0A2X4RCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

38301:DQN65 RS07200
gene id: 38301:DQN65_RS07200
uniprot id: A0A2X4RE07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

38301:DQN65 RS05490
gene id: 38301:DQN65_RS05490
uniprot id: A0A2X4RCX3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

38301:DQN65 RS07735
gene id: 38301:DQN65_RS07735
uniprot id: A0A2X4RMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

38301:DQN65 RS09420
gene id: 38301:DQN65_RS09420
uniprot id: A0A2X4UR76
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08855
gene id: 38301:DQN65_RS08855
uniprot id: A0A2X4RE08
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

38301:DQN65 RS04955
gene id: 38301:DQN65_RS04955
uniprot id: A0A2X4RBW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

38301:DQN65 RS10510
gene id: 38301:DQN65_RS10510
uniprot id: A0A2X4RG58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

38301:DQN65 RS09460
gene id: 38301:DQN65_RS09460
uniprot id: A0A2X4RTP2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS11630
gene id: 38301:DQN65_RS11630
uniprot id: A0A2X4RQ08
names: Similarity
messages: Belongs to the catalase family.

38301:DQN65 RS08280
gene id: 38301:DQN65_RS08280
uniprot id: A0A2X4UQM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

38301:DQN65 RS11050
gene id: 38301:DQN65_RS11050
uniprot id: A0A2X4RF83
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

38301:DQN65 RS00595
gene id: 38301:DQN65_RS00595
uniprot id: A0A2X4U6F8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS05300
gene id: 38301:DQN65_RS05300
uniprot id: A0A2X4RCP1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS05440
gene id: 38301:DQN65_RS05440
uniprot id: A0A2X4RCW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS01330
gene id: 38301:DQN65_RS01330
uniprot id: A0A2X4R5M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

38301:DQN65 RS04235
gene id: 38301:DQN65_RS04235
uniprot id: A0A2X4RBZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS11815
gene id: 38301:DQN65_RS11815
uniprot id: A0A2X4USI5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

38301:DQN65 RS00770
gene id: 38301:DQN65_RS00770
uniprot id: A0A2X4RH13
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00180
gene id: 38301:DQN65_RS00180
uniprot id: A0A2X4RGD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

38301:DQN65 RS09270
gene id: 38301:DQN65_RS09270
uniprot id: A0A2X4UDF4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS10760
gene id: 38301:DQN65_RS10760
uniprot id: A0A2X4RFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

38301:DQN65 RS09695
gene id: 38301:DQN65_RS09695
uniprot id: A0A2X4RF25
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS10785
gene id: 38301:DQN65_RS10785
uniprot id: A0A0B2Z208
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

38301:DQN65 RS07875
gene id: 38301:DQN65_RS07875
uniprot id: A0A2X4UCL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

38301:DQN65 RS05710
gene id: 38301:DQN65_RS05710
uniprot id: A0A2X4RRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

38301:DQN65 RS06890
gene id: 38301:DQN65_RS06890
uniprot id: A0A2X4RE04
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

38301:DQN65 RS08310
gene id: 38301:DQN65_RS08310
uniprot id: A0A2X4RVQ2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

38301:DQN65 RS05675
gene id: 38301:DQN65_RS05675
uniprot id: A0A2X4UB89
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

38301:DQN65 RS09190
gene id: 38301:DQN65_RS09190
uniprot id: A0A2X4RF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS01780
gene id: 38301:DQN65_RS01780
uniprot id: A0A2X4UL07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS04350
gene id: 38301:DQN65_RS04350
uniprot id: A0A2X4RTD9
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08025
gene id: 38301:DQN65_RS08025
uniprot id: A0A2X4UQH0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

38301:DQN65 RS05770
gene id: 38301:DQN65_RS05770
uniprot id: A0A2X4UPA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS10300
gene id: 38301:DQN65_RS10300
uniprot id: A0A2X4RFD2
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

38301:DQN65 RS07170
gene id: 38301:DQN65_RS07170
uniprot id: A0A2X4RE69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

38301:DQN65 RS07445
gene id: 38301:DQN65_RS07445
uniprot id: A0A2X4RMQ8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

38301:DQN65 RS02200
gene id: 38301:DQN65_RS02200
uniprot id: A0A2X4RN25
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09265
gene id: 38301:DQN65_RS09265
uniprot id: A0A2X4UR59
names: Similarity
messages: Belongs to the TPP enzyme family.

38301:DQN65 RS06480
gene id: 38301:DQN65_RS06480
uniprot id: A0A2X4UPP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

38301:DQN65 RS01595
gene id: 38301:DQN65_RS01595
uniprot id: A0A2X4U7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

38301:DQN65 RS02825
gene id: 38301:DQN65_RS02825
uniprot id: A0A2X4R9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS06815
gene id: 38301:DQN65_RS06815
uniprot id: A0A2X4RMB0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

38301:DQN65 RS04485
gene id: 38301:DQN65_RS04485
uniprot id: A0A2X4RKS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

38301:DQN65 RS11665
gene id: 38301:DQN65_RS11665
uniprot id: A0A2X4UF36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS03680
gene id: 38301:DQN65_RS03680
uniprot id: A0A2X4UMW6
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

38301:DQN65 RS09950
gene id: 38301:DQN65_RS09950
uniprot id: A0A2X4RF70
names: Similarity
messages: Belongs to the peptidase C40 family.

38301:DQN65 RS11320
gene id: 38301:DQN65_RS11320
uniprot id: A0A2X4UEV8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS10535
gene id: 38301:DQN65_RS10535
uniprot id: A0A2X4RPB7
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11800
gene id: 38301:DQN65_RS11800
uniprot id: A0A2X4RG63
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS07940
gene id: 38301:DQN65_RS07940
uniprot id: A0A2X4RN00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS11480
gene id: 38301:DQN65_RS11480
uniprot id: A0A2X4RPX4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS10105
gene id: 38301:DQN65_RS10105
uniprot id: A0A2X4RFW3
names: Similarity
messages: Belongs to the pyruvate kinase family.

38301:DQN65 RS09465
gene id: 38301:DQN65_RS09465
uniprot id: A0A2X4RFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS01995
gene id: 38301:DQN65_RS01995
uniprot id: A0A2X4R9W5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

38301:DQN65 RS06905
gene id: 38301:DQN65_RS06905
uniprot id: A0A2X4RCY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

38301:DQN65 RS02735
gene id: 38301:DQN65_RS02735
uniprot id: A0A2X4RNK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

38301:DQN65 RS02820
gene id: 38301:DQN65_RS02820
uniprot id: A0A2X4UM02
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

38301:DQN65 RS00800
gene id: 38301:DQN65_RS00800
uniprot id: A0A2X4R871
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

38301:DQN65 RS12060
gene id: 38301:DQN65_RS12060
uniprot id: A0A2X4RGQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

38301:DQN65 RS10500
gene id: 38301:DQN65_RS10500
uniprot id: A0A2X4RFG7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

38301:DQN65 RS08400
gene id: 38301:DQN65_RS08400
uniprot id: A0A2X4RN77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

38301:DQN65 RS06110
gene id: 38301:DQN65_RS06110
uniprot id: A0A2X4RRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS10670
gene id: 38301:DQN65_RS10670
uniprot id: A0A2X4UE95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

38301:DQN65 RS11440
gene id: 38301:DQN65_RS11440
uniprot id: A0A2X4RXE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

38301:DQN65 RS07245
gene id: 38301:DQN65_RS07245
uniprot id: A0A2X4RML3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

38301:DQN65 RS05735
gene id: 38301:DQN65_RS05735
uniprot id: A0A2X4R966
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

38301:DQN65 RS04375
gene id: 38301:DQN65_RS04375
uniprot id: A0A2X4RKP2
names: Similarity
messages: Belongs to the P(II) protein family.

38301:DQN65 RS07895
gene id: 38301:DQN65_RS07895
uniprot id: A0A2X4REF7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

38301:DQN65 RS03590
gene id: 38301:DQN65_RS03590
uniprot id: A0A2X4RPL2
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

38301:DQN65 RS10865
gene id: 38301:DQN65_RS10865
uniprot id: A0A2X4RPH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

38301:DQN65 RS10450
gene id: 38301:DQN65_RS10450
uniprot id: A0A0B2Z0J1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

38301:DQN65 RS06550
gene id: 38301:DQN65_RS06550
uniprot id: A0A2X4RM56
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

38301:DQN65 RS05545
gene id: 38301:DQN65_RS05545
uniprot id: A0A2X4RU60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

38301:DQN65 RS04020
gene id: 38301:DQN65_RS04020
uniprot id: A0A2X4RQ19
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

38301:DQN65 RS04575
gene id: 38301:DQN65_RS04575
uniprot id: A0A2X4RKU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

38301:DQN65 RS04505
gene id: 38301:DQN65_RS04505
uniprot id: A0A2X4RQR6
names: Similarity
messages: Belongs to the DprA/Smf family.

38301:DQN65 RS06725
gene id: 38301:DQN65_RS06725
uniprot id: A0A2X4RDX3
names: Similarity
messages: Belongs to the Nudix hydrolase family.

38301:DQN65 RS05670
gene id: 38301:DQN65_RS05670
uniprot id: A0A2X4UP82
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

38301:DQN65 RS07250
gene id: 38301:DQN65_RS07250
uniprot id: A0A2X4RE19
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02420
gene id: 38301:DQN65_RS02420
uniprot id: A0A2X4RA64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

38301:DQN65 RS10555
gene id: 38301:DQN65_RS10555
uniprot id: A0A2X4RUC4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS10435
gene id: 38301:DQN65_RS10435
uniprot id: A0A2X4RBL7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

38301:DQN65 RS03350
gene id: 38301:DQN65_RS03350
uniprot id: A0A2X4RB53
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04290
gene id: 38301:DQN65_RS04290
uniprot id: A0A2X4RCD2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

38301:DQN65 RS10780
gene id: 38301:DQN65_RS10780
uniprot id: A0A2X4UEB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

38301:DQN65 RS06095
gene id: 38301:DQN65_RS06095
uniprot id: A0A2X4RDB6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02790
gene id: 38301:DQN65_RS02790
uniprot id: A0A0B2YXJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

38301:DQN65 RS12110
gene id: 38301:DQN65_RS12110
uniprot id: A0A2X4RGR4
names: Similarity
messages: Belongs to the peptidase M13 family.

38301:DQN65 RS03045
gene id: 38301:DQN65_RS03045
uniprot id: A0A2X4U8W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

38301:DQN65 RS02070
gene id: 38301:DQN65_RS02070
uniprot id: A0A2X4RQT4
names: Similarity
messages: Belongs to the PhoU family.

38301:DQN65 RS02740
gene id: 38301:DQN65_RS02740
uniprot id: A0A2X4ULX4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

38301:DQN65 RS00385
gene id: 38301:DQN65_RS00385
uniprot id: A0A2X4R7X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

38301:DQN65 RS10380
gene id: 38301:DQN65_RS10380
uniprot id: A0A0B2Z0V9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

38301:DQN65 RS02525
gene id: 38301:DQN65_RS02525
uniprot id: A0A2X4R9M9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

38301:DQN65 RS05645
gene id: 38301:DQN65_RS05645
uniprot id: A0A2X4RD07
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09185
gene id: 38301:DQN65_RS09185
uniprot id: A0A2X4RNL8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

38301:DQN65 RS01920
gene id: 38301:DQN65_RS01920
uniprot id: A0A2X4RI27
names: Similarity
messages: Belongs to the SAICAR synthetase family.

38301:DQN65 RS02985
gene id: 38301:DQN65_RS02985
uniprot id: A0A2X4RA34
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

38301:DQN65 RS03780
gene id: 38301:DQN65_RS03780
uniprot id: A0A2X4RSQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

38301:DQN65 RS00105
gene id: 38301:DQN65_RS00105
uniprot id: A0A2X4R7H5
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07605
gene id: 38301:DQN65_RS07605
uniprot id: A0A2X4REH6
names: Similarity
messages: Belongs to the LOG family.

38301:DQN65 RS01570
gene id: 38301:DQN65_RS01570
uniprot id: A0A2X4RHP5
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02755
gene id: 38301:DQN65_RS02755
uniprot id: A0A2X4RRH8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

38301:DQN65 RS11680
gene id: 38301:DQN65_RS11680
uniprot id: A0A2X4RQ21
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

38301:DQN65 RS10685
gene id: 38301:DQN65_RS10685
uniprot id: A0A2X4RPE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

38301:DQN65 RS09570
gene id: 38301:DQN65_RS09570
uniprot id: A0A2X4UDK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

38301:DQN65 RS02320
gene id: 38301:DQN65_RS02320
uniprot id: A0A2X4RA31
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07750
gene id: 38301:DQN65_RS07750
uniprot id: A0A2X4RVE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

38301:DQN65 RS03565
gene id: 38301:DQN65_RS03565
uniprot id: A0A2X4RBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

38301:DQN65 RS03005
gene id: 38301:DQN65_RS03005
uniprot id: A0A2X4RAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS04615
gene id: 38301:DQN65_RS04615
uniprot id: A0A2X4UAK9
names: Similarity
messages: Belongs to the MQO family.

38301:DQN65 RS07230
gene id: 38301:DQN65_RS07230
uniprot id: A0A2X4UC74
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS01760
gene id: 38301:DQN65_RS01760
uniprot id: A0A2X4R5Z0
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

38301:DQN65 RS01800
gene id: 38301:DQN65_RS01800
uniprot id: A0A2X4R9L0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS00045
gene id: 38301:DQN65_RS00045
uniprot id: A0A2X4R7E3
names: Similarity
messages: Belongs to the ParB family.

38301:DQN65 RS03075
gene id: 38301:DQN65_RS03075
uniprot id: A0A2X4RRW6
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS08850
gene id: 38301:DQN65_RS08850
uniprot id: A0A2X4UD71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

38301:DQN65 RS02590
gene id: 38301:DQN65_RS02590
uniprot id: A0A2X4RAB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS01725
gene id: 38301:DQN65_RS01725
uniprot id: A0A2X4R9K2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

38301:DQN65 RS07905
gene id: 38301:DQN65_RS07905
uniprot id: A0A2X4RE64
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS10890
gene id: 38301:DQN65_RS10890
uniprot id: A0A2X4RGI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS05375
gene id: 38301:DQN65_RS05375
uniprot id: A0A2X4RC36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

38301:DQN65 RS03810
gene id: 38301:DQN65_RS03810
uniprot id: A0A2X4RSR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

38301:DQN65 RS05390
gene id: 38301:DQN65_RS05390
uniprot id: A0A2X4RCU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS08560
gene id: 38301:DQN65_RS08560
uniprot id: A0A2X4RVU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS01700
gene id: 38301:DQN65_RS01700
uniprot id: A0A2X4R5X2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS12160
gene id: 38301:DQN65_RS12160
uniprot id: A0A2X4RGS7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

38301:DQN65 RS01360
gene id: 38301:DQN65_RS01360
uniprot id: A0A2X4R9A1
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09020
gene id: 38301:DQN65_RS09020
uniprot id: A0A2X4UDB1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

38301:DQN65 RS07240
gene id: 38301:DQN65_RS07240
uniprot id: A0A2X4R9Y2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

38301:DQN65 RS09135
gene id: 38301:DQN65_RS09135
uniprot id: A0A2X4RNK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

38301:DQN65 RS10145
gene id: 38301:DQN65_RS10145
uniprot id: A0A2X4RFA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

38301:DQN65 RS04800
gene id: 38301:DQN65_RS04800
uniprot id: A0A2X4UAR1
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06940
gene id: 38301:DQN65_RS06940
uniprot id: A0A2X4RE15
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

38301:DQN65 RS02750
gene id: 38301:DQN65_RS02750
uniprot id: A0A2X4RIU8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

38301:DQN65 RS03395
gene id: 38301:DQN65_RS03395
uniprot id: A0A2X4RAH2
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

38301:DQN65 RS08535
gene id: 38301:DQN65_RS08535
uniprot id: A0A2X4UD02
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

38301:DQN65 RS01610
gene id: 38301:DQN65_RS01610
uniprot id: A0A2X4R9F1
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

38301:DQN65 RS02815
gene id: 38301:DQN65_RS02815
uniprot id: A0A0B2YZM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

38301:DQN65 RS05015
gene id: 38301:DQN65_RS05015
uniprot id: A0A2X4RL71
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS00225
gene id: 38301:DQN65_RS00225
uniprot id: A0A2X4U5Z4
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

38301:DQN65 RS04085
gene id: 38301:DQN65_RS04085
uniprot id: A0A2X4RBU7
names: Similarity
messages: Belongs to the asparaginase 1 family.

38301:DQN65 RS00165
gene id: 38301:DQN65_RS00165
uniprot id: A0A2X4RL95
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04015
gene id: 38301:DQN65_RS04015
uniprot id: A0A2X4RBS2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

38301:DQN65 RS02380
gene id: 38301:DQN65_RS02380
uniprot id: A0A2X4ULJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

38301:DQN65 RS09090
gene id: 38301:DQN65_RS09090
uniprot id: A0A2X4RF36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

38301:DQN65 RS04510
gene id: 38301:DQN65_RS04510
uniprot id: A0A2X4RCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

38301:DQN65 RS12350
gene id: 38301:DQN65_RS12350
uniprot id: A0A2X4RG12
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11915
gene id: 38301:DQN65_RS11915
uniprot id: A0A2X4RH63
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS01390
gene id: 38301:DQN65_RS01390
uniprot id: A0A2X4R8Q4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

38301:DQN65 RS12130
gene id: 38301:DQN65_RS12130
uniprot id: A0A2X4RHA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Mmr subfamily.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS04315
gene id: 38301:DQN65_RS04315
uniprot id: A0A2X4UNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

38301:DQN65 RS10545
gene id: 38301:DQN65_RS10545
uniprot id: A0A2X4RWV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

38301:DQN65 RS09355
gene id: 38301:DQN65_RS09355
uniprot id: A0A2X4RTM2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS00620
gene id: 38301:DQN65_RS00620
uniprot id: A0A2X4R823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS05745
gene id: 38301:DQN65_RS05745
uniprot id: A0A2X4RD32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

38301:DQN65 RS04535
gene id: 38301:DQN65_RS04535
uniprot id: A0A2X4RKT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

38301:DQN65 RS01370
gene id: 38301:DQN65_RS01370
uniprot id: A0A2X4U769
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

38301:DQN65 RS06680
gene id: 38301:DQN65_RS06680
uniprot id: A0A2X4UPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

38301:DQN65 RS04320
gene id: 38301:DQN65_RS04320
uniprot id: A0A2X4RBG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

38301:DQN65 RS02505
gene id: 38301:DQN65_RS02505
uniprot id: A0A2X4RA90
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07330
gene id: 38301:DQN65_RS07330
uniprot id: A0A2X4UC96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

38301:DQN65 RS08395
gene id: 38301:DQN65_RS08395
uniprot id: A0A0B2YP71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

38301:DQN65 RS00625
gene id: 38301:DQN65_RS00625
uniprot id: A0A2X4RGU8
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02695
gene id: 38301:DQN65_RS02695
uniprot id: A0A2X4RIT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

38301:DQN65 RS05655
gene id: 38301:DQN65_RS05655
uniprot id: A0A2X4RCV8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

38301:DQN65 RS03930
gene id: 38301:DQN65_RS03930
uniprot id: A0A2X4RSW8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

38301:DQN65 RS05195
gene id: 38301:DQN65_RS05195
uniprot id: A0A2X4RC07
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS05020
gene id: 38301:DQN65_RS05020
uniprot id: A0A2X4RCM4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

38301:DQN65 RS01020
gene id: 38301:DQN65_RS01020
uniprot id: A0A2X4RPY1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS05340
gene id: 38301:DQN65_RS05340
uniprot id: A0A2X4RCT5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

38301:DQN65 RS02700
gene id: 38301:DQN65_RS02700
uniprot id: A0A2X4RRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

38301:DQN65 RS04620
gene id: 38301:DQN65_RS04620
uniprot id: A0A2X4R8P0
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

38301:DQN65 RS07785
gene id: 38301:DQN65_RS07785
uniprot id: A0A2X4RA97
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS05495
gene id: 38301:DQN65_RS05495
uniprot id: A0A2X4RU48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

38301:DQN65 RS08380
gene id: 38301:DQN65_RS08380
uniprot id: A0A2X4UQN8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

38301:DQN65 RS00975
gene id: 38301:DQN65_RS00975
uniprot id: A0A2X4RH87
names: Similarity
messages: Belongs to the AccD/PCCB family.

38301:DQN65 RS06860
gene id: 38301:DQN65_RS06860
uniprot id: A0A2X4R9Q2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS04880
gene id: 38301:DQN65_RS04880
uniprot id: A0A2X4RCG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

38301:DQN65 RS01835
gene id: 38301:DQN65_RS01835
uniprot id: A0A2X4R618
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

38301:DQN65 RS03320
gene id: 38301:DQN65_RS03320
uniprot id: A0A2X4R7G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

38301:DQN65 RS00630
gene id: 38301:DQN65_RS00630
uniprot id: A0A2X4RPH5
names: Similarity
messages: Belongs to the thioredoxin family.

38301:DQN65 RS08385
gene id: 38301:DQN65_RS08385
uniprot id: A0A0B2YWT2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

38301:DQN65 RS10720
gene id: 38301:DQN65_RS10720
uniprot id: A0A2X4URW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

38301:DQN65 RS01405
gene id: 38301:DQN65_RS01405
uniprot id: A0A2X4RMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

38301:DQN65 RS04120
gene id: 38301:DQN65_RS04120
uniprot id: A0A2X4UA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

38301:DQN65 RS02275
gene id: 38301:DQN65_RS02275
uniprot id: A0A2X4RA48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

38301:DQN65 RS00130
gene id: 38301:DQN65_RS00130
uniprot id: A0A2X4R7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

38301:DQN65 RS01005
gene id: 38301:DQN65_RS01005
uniprot id: A0A2X4R923
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS10115
gene id: 38301:DQN65_RS10115
uniprot id: A0A2X4UDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

38301:DQN65 RS10430
gene id: 38301:DQN65_RS10430
uniprot id: A0A2X4REV6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

38301:DQN65 RS09385
gene id: 38301:DQN65_RS09385
uniprot id: A0A2X4RNP6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

38301:DQN65 RS10935
gene id: 38301:DQN65_RS10935
uniprot id: A0A2X4RUK2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04395
gene id: 38301:DQN65_RS04395
uniprot id: A0A2X4RBI9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

38301:DQN65 RS07615
gene id: 38301:DQN65_RS07615
uniprot id: A0A2X4UCH0
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11895
gene id: 38301:DQN65_RS11895
uniprot id: A0A2X4RGN0
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03835
gene id: 38301:DQN65_RS03835
uniprot id: A0A2X4RBM0
names: Similarity
messages: Belongs to the asparagine synthetase family.

38301:DQN65 RS07870
gene id: 38301:DQN65_RS07870
uniprot id: A0A2X4UQE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

38301:DQN65 RS07435
gene id: 38301:DQN65_RS07435
uniprot id: A0A2X4RD88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

38301:DQN65 RS03995
gene id: 38301:DQN65_RS03995
uniprot id: A0A2X4U9X0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS07220
gene id: 38301:DQN65_RS07220
uniprot id: A0A2X4RE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

38301:DQN65 RS02090
gene id: 38301:DQN65_RS02090
uniprot id: A0A2X4R9B7
names: Similarity
messages: Belongs to the CsoR family.

38301:DQN65 RS10675
gene id: 38301:DQN65_RS10675
uniprot id: A0A2X4RF14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

38301:DQN65 RS12265
gene id: 38301:DQN65_RS12265
uniprot id: A0A2X4RXX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

38301:DQN65 RS08665
gene id: 38301:DQN65_RS08665
uniprot id: A0A2X4RTA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

38301:DQN65 RS02255
gene id: 38301:DQN65_RS02255
uniprot id: A0A2X4R6D8
names: Function
names: Similarity
messages: Belongs to the NrdI family.
messages: Probably involved in ribonucleotide reductase function.

38301:DQN65 RS10230
gene id: 38301:DQN65_RS10230
uniprot id: A0A2X4RP60
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

38301:DQN65 RS06605
gene id: 38301:DQN65_RS06605
uniprot id: A0A2X4RDM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

38301:DQN65 RS07215
gene id: 38301:DQN65_RS07215
uniprot id: A0A2X4RSF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

38301:DQN65 RS03745
gene id: 38301:DQN65_RS03745
uniprot id: A0A2X4RAV9
names: Similarity
messages: Belongs to the glutamine synthetase family.

38301:DQN65 RS10195
gene id: 38301:DQN65_RS10195
uniprot id: A0A2X4RFB6
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09360
gene id: 38301:DQN65_RS09360
uniprot id: A0A2X4RFG3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

38301:DQN65 RS05720
gene id: 38301:DQN65_RS05720
uniprot id: A0A2X4UP93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

38301:DQN65 RS03330
gene id: 38301:DQN65_RS03330
uniprot id: A0A2X4RP97
names: Similarity
messages: Belongs to the CsoR family.

38301:DQN65 RS12095
gene id: 38301:DQN65_RS12095
uniprot id: A0A2X4RFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 85 family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS10455
gene id: 38301:DQN65_RS10455
uniprot id: A0A0B2YX66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

38301:DQN65 RS01465
gene id: 38301:DQN65_RS01465
uniprot id: A0A2X4UKP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS06485
gene id: 38301:DQN65_RS06485
uniprot id: A0A2X4UBP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS10390
gene id: 38301:DQN65_RS10390
uniprot id: A0A2X4RP89
names: Similarity
messages: Belongs to the WXG100 family.

38301:DQN65 RS03455
gene id: 38301:DQN65_RS03455
uniprot id: A0A2X4RAJ3
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03205
gene id: 38301:DQN65_RS03205
uniprot id: A0A2X4RS20
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

38301:DQN65 RS07950
gene id: 38301:DQN65_RS07950
uniprot id: A0A2X4RVI2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS08350
gene id: 38301:DQN65_RS08350
uniprot id: A0A2X4RN64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

38301:DQN65 RS10385
gene id: 38301:DQN65_RS10385
uniprot id: A0A2X4RBK9
names: Similarity
messages: Belongs to the WXG100 family.

38301:DQN65 RS04925
gene id: 38301:DQN65_RS04925
uniprot id: A0A2X4RTT7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS11500
gene id: 38301:DQN65_RS11500
uniprot id: A0A2X4RUX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

38301:DQN65 RS05295
gene id: 38301:DQN65_RS05295
uniprot id: A0A2X4RU10
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

38301:DQN65 RS08250
gene id: 38301:DQN65_RS08250
uniprot id: A0A2X4RN45
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

38301:DQN65 RS10630
gene id: 38301:DQN65_RS10630
uniprot id: A0A2X4RBQ9
names: Similarity
messages: Belongs to the asp23 family.

38301:DQN65 RS05565
gene id: 38301:DQN65_RS05565
uniprot id: A0A2X4UP65
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

38301:DQN65 RS10590
gene id: 38301:DQN65_RS10590
uniprot id: A0A2X4RFY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

38301:DQN65 RS01585
gene id: 38301:DQN65_RS01585
uniprot id: A0A2X4U7C6
names: Similarity
messages: Belongs to the peptidase S13 family.

38301:DQN65 RS01185
gene id: 38301:DQN65_RS01185
uniprot id: A0A2X4R968
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS07310
gene id: 38301:DQN65_RS07310
uniprot id: A0A2X4RDU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

38301:DQN65 RS01500
gene id: 38301:DQN65_RS01500
uniprot id: A0A2X4R9C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

38301:DQN65 RS01495
gene id: 38301:DQN65_RS01495
uniprot id: A0A2X4RQ90
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00870
gene id: 38301:DQN65_RS00870
uniprot id: A0A2X4R8A4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

38301:DQN65 RS08985
gene id: 38301:DQN65_RS08985
uniprot id: A0A2X4RNH9
names: Similarity
messages: Belongs to the peptidase S16 family.

38301:DQN65 RS08515
gene id: 38301:DQN65_RS08515
uniprot id: A0A2X4REH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

38301:DQN65 RS05825
gene id: 38301:DQN65_RS05825
uniprot id: A0A2X4UBB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS07890
gene id: 38301:DQN65_RS07890
uniprot id: A0A2X4RMZ1
names: Similarity
messages: Belongs to the FBPase class 2 family.

38301:DQN65 RS11330
gene id: 38301:DQN65_RS11330
uniprot id: A0A2X4RC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily.
messages: Periplasm

38301:DQN65 RS02010
gene id: 38301:DQN65_RS02010
uniprot id: A0A2X4R673
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

38301:DQN65 RS03250
gene id: 38301:DQN65_RS03250
uniprot id: A0A2X4RB88
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06590
gene id: 38301:DQN65_RS06590
uniprot id: A0A2X4RCS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02475
gene id: 38301:DQN65_RS02475
uniprot id: A0A2X4RR66
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

38301:DQN65 RS11735
gene id: 38301:DQN65_RS11735
uniprot id: A0A2X4RCF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

38301:DQN65 RS01480
gene id: 38301:DQN65_RS01480
uniprot id: A0A2X4R5Q0
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06455
gene id: 38301:DQN65_RS06455
uniprot id: A0A2X4RDJ2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02550
gene id: 38301:DQN65_RS02550
uniprot id: A0A2X4U8C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

38301:DQN65 RS01785
gene id: 38301:DQN65_RS01785
uniprot id: A0A2X4R5Z9
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

38301:DQN65 RS05820
gene id: 38301:DQN65_RS05820
uniprot id: A0A2X4UPB5
names: Similarity
messages: Belongs to the TlyA family.

38301:DQN65 RS00475
gene id: 38301:DQN65_RS00475
uniprot id: A0A2X4RGQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

38301:DQN65 RS06285
gene id: 38301:DQN65_RS06285
uniprot id: A0A2X4RCL7
names: Similarity
messages: Belongs to the UPF0098 family.

38301:DQN65 RS01170
gene id: 38301:DQN65_RS01170
uniprot id: A0A2X4U720
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06405
gene id: 38301:DQN65_RS06405
uniprot id: A0A2X4RDI2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS04970
gene id: 38301:DQN65_RS04970
uniprot id: A0A2X4RCL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

38301:DQN65 RS07065
gene id: 38301:DQN65_RS07065
uniprot id: A0A2X4RDX2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS12435
gene id: 38301:DQN65_RS12435
uniprot id: A0A2X4RHG4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

38301:DQN65 RS10345
gene id: 38301:DQN65_RS10345
uniprot id: A0A2X4RFT6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

38301:DQN65 RS04930
gene id: 38301:DQN65_RS04930
uniprot id: A0A2X4RCH6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

38301:DQN65 RS04105
gene id: 38301:DQN65_RS04105
uniprot id: A0A2X4RBT8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

38301:DQN65 RS03175
gene id: 38301:DQN65_RS03175
uniprot id: A0A2X4RJC3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

38301:DQN65 RS05765
gene id: 38301:DQN65_RS05765
uniprot id: A0A2X4RDC9
names: Similarity
messages: Belongs to the UPF0434 family.

38301:DQN65 RS00710
gene id: 38301:DQN65_RS00710
uniprot id: A0A2X4R857
names: Similarity
messages: Belongs to the universal stress protein A family.

38301:DQN65 RS05715
gene id: 38301:DQN65_RS05715
uniprot id: A0A2X4RDC0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

38301:DQN65 RS01260
gene id: 38301:DQN65_RS01260
uniprot id: A0A2X4R979
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

38301:DQN65 RS02120
gene id: 38301:DQN65_RS02120
uniprot id: A0A2X4RQU5
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

38301:DQN65 RS10830
gene id: 38301:DQN65_RS10830
uniprot id: A0A2X4RFM4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

38301:DQN65 RS06525
gene id: 38301:DQN65_RS06525
uniprot id: A0A2X4RDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

38301:DQN65 RS11430
gene id: 38301:DQN65_RS11430
uniprot id: A0A2X4RC88
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.

38301:DQN65 RS02195
gene id: 38301:DQN65_RS02195
uniprot id: A0A2X4R9Z0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

38301:DQN65 RS09910
gene id: 38301:DQN65_RS09910
uniprot id: A0A2X4RFR8
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

38301:DQN65 RS10055
gene id: 38301:DQN65_RS10055
uniprot id: A0A2X4RU17
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11685
gene id: 38301:DQN65_RS11685
uniprot id: A0A2X4RGI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

38301:DQN65 RS00235
gene id: 38301:DQN65_RS00235
uniprot id: A0A2X4R7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

38301:DQN65 RS06945
gene id: 38301:DQN65_RS06945
uniprot id: A0A2X4UPX0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

38301:DQN65 RS00715
gene id: 38301:DQN65_RS00715
uniprot id: A0A2X4RLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

38301:DQN65 RS11890
gene id: 38301:DQN65_RS11890
uniprot id: A0A2X4RQ63
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS10375
gene id: 38301:DQN65_RS10375
uniprot id: A0A2X4UE30
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

38301:DQN65 RS06565
gene id: 38301:DQN65_RS06565
uniprot id: A0A2X4RDD2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

38301:DQN65 RS03190
gene id: 38301:DQN65_RS03190
uniprot id: A0A2X4RB55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

38301:DQN65 RS07800
gene id: 38301:DQN65_RS07800
uniprot id: A0A2X4RVF0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS09750
gene id: 38301:DQN65_RS09750
uniprot id: A0A2X4RF35
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

38301:DQN65 RS02920
gene id: 38301:DQN65_RS02920
uniprot id: A0A2X4RAN3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

38301:DQN65 RS11870
gene id: 38301:DQN65_RS11870
uniprot id: A0A2X4USJ5
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04480
gene id: 38301:DQN65_RS04480
uniprot id: A0A2X4R8K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

38301:DQN65 RS11645
gene id: 38301:DQN65_RS11645
uniprot id: A0A2X4RG38
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS01960
gene id: 38301:DQN65_RS01960
uniprot id: A0A2X4R9S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

38301:DQN65 RS10305
gene id: 38301:DQN65_RS10305
uniprot id: A0A2X4RU68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

38301:DQN65 RS00880
gene id: 38301:DQN65_RS00880
uniprot id: A0A2X4R8W3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

38301:DQN65 RS07440
gene id: 38301:DQN65_RS07440
uniprot id: A0A2X4RA26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

38301:DQN65 RS10875
gene id: 38301:DQN65_RS10875
uniprot id: A0A2X4RX18
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Could possibly oxidize fatty acids using specific components.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS04335
gene id: 38301:DQN65_RS04335
uniprot id: A0A2X4UNH7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

38301:DQN65 RS00885
gene id: 38301:DQN65_RS00885
uniprot id: A0A2X4U6S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

38301:DQN65 RS11805
gene id: 38301:DQN65_RS11805
uniprot id: A0A2X4RV41
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02325
gene id: 38301:DQN65_RS02325
uniprot id: A0A2X4RA68
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

38301:DQN65 RS06640
gene id: 38301:DQN65_RS06640
uniprot id: A0A2X4RCT4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

38301:DQN65 RS05475
gene id: 38301:DQN65_RS05475
uniprot id: A0A2X4RC55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS11565
gene id: 38301:DQN65_RS11565
uniprot id: A0A2X4UF09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

38301:DQN65 RS04045
gene id: 38301:DQN65_RS04045
uniprot id: A0A2X4RB58
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

38301:DQN65 RS10035
gene id: 38301:DQN65_RS10035
uniprot id: A0A2X4RP16
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

38301:DQN65 RS06170
gene id: 38301:DQN65_RS06170
uniprot id: A0A2X4RDM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

38301:DQN65 RS10905
gene id: 38301:DQN65_RS10905
uniprot id: A0A2X4RF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS01855
gene id: 38301:DQN65_RS01855
uniprot id: A0A2X4R949
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

38301:DQN65 RS06580
gene id: 38301:DQN65_RS06580
uniprot id: A0A2X4UPQ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

38301:DQN65 RS07300
gene id: 38301:DQN65_RS07300
uniprot id: A0A2X4RE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS01235
gene id: 38301:DQN65_RS01235
uniprot id: A0A2X4R5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

38301:DQN65 RS06215
gene id: 38301:DQN65_RS06215
uniprot id: A0A2X4RRT9
names: Similarity
messages: Belongs to the peptidase M18 family.

38301:DQN65 RS12325
gene id: 38301:DQN65_RS12325
uniprot id: A0A2X4RVE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS12225
gene id: 38301:DQN65_RS12225
uniprot id: A0A2X4RVC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

38301:DQN65 RS01950
gene id: 38301:DQN65_RS01950
uniprot id: A0A0B2YL67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

38301:DQN65 RS10010
gene id: 38301:DQN65_RS10010
uniprot id: A0A2X4RFU2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

38301:DQN65 RS05920
gene id: 38301:DQN65_RS05920
uniprot id: A0A2X4UPD8
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

38301:DQN65 RS00015
gene id: 38301:DQN65_RS00015
uniprot id: A0A0B2Z466
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

38301:DQN65 RS07130
gene id: 38301:DQN65_RS07130
uniprot id: A0A2X4UC53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

38301:DQN65 RS12255
gene id: 38301:DQN65_RS12255
uniprot id: A0A2X4RQD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

38301:DQN65 RS06975
gene id: 38301:DQN65_RS06975
uniprot id: A0A2X4RS97
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

38301:DQN65 RS10160
gene id: 38301:DQN65_RS10160
uniprot id: A0A2X4URK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS10440
gene id: 38301:DQN65_RS10440
uniprot id: A0A2X4RP98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

38301:DQN65 RS11695
gene id: 38301:DQN65_RS11695
uniprot id: A0A2X4RG47
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

38301:DQN65 RS04740
gene id: 38301:DQN65_RS04740
uniprot id: A0A2X4RCR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

38301:DQN65 RS10790
gene id: 38301:DQN65_RS10790
uniprot id: A0A2X4RBT6
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

38301:DQN65 RS01880
gene id: 38301:DQN65_RS01880
uniprot id: A0A2X4RMU8
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS06205
gene id: 38301:DQN65_RS06205
uniprot id: A0A2X4RUI9
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

38301:DQN65 RS05200
gene id: 38301:DQN65_RS05200
uniprot id: A0A2X4R8Y1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

38301:DQN65 RS06025
gene id: 38301:DQN65_RS06025
uniprot id: A0A2X4UPF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

38301:DQN65 RS11075
gene id: 38301:DQN65_RS11075
uniprot id: A0A2X4RFS2
names: Similarity
messages: Belongs to the LOR family.

38301:DQN65 RS03090
gene id: 38301:DQN65_RS03090
uniprot id: A0A2X4RA66
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

38301:DQN65 RS00245
gene id: 38301:DQN65_RS00245
uniprot id: A0A2X4UJN9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS08480
gene id: 38301:DQN65_RS08480
uniprot id: A0A2X4UQQ7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS02585
gene id: 38301:DQN65_RS02585
uniprot id: A0A2X4RRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS12460
gene id: 38301:DQN65_RS12460
uniprot id: A0A2X4RQI3
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS02500
gene id: 38301:DQN65_RS02500
uniprot id: A0A2X4R9Q8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

38301:DQN65 RS04795
gene id: 38301:DQN65_RS04795
uniprot id: A0A2X4UNT6
names: Similarity
messages: Belongs to the PspA/IM30 family.

38301:DQN65 RS09930
gene id: 38301:DQN65_RS09930
uniprot id: A0A2X4RBB4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

38301:DQN65 RS07745
gene id: 38301:DQN65_RS07745
uniprot id: A0A2X4REC5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

38301:DQN65 RS05395
gene id: 38301:DQN65_RS05395
uniprot id: A0A2X4RU27
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

38301:DQN65 RS03815
gene id: 38301:DQN65_RS03815
uniprot id: A0A2X4RPU5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

38301:DQN65 RS06425
gene id: 38301:DQN65_RS06425
uniprot id: A0A2X4RDR7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

38301:DQN65 RS08710
gene id: 38301:DQN65_RS08710
uniprot id: A0A2X4REK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

38301:DQN65 RS10680
gene id: 38301:DQN65_RS10680
uniprot id: A0A2X4RBR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

38301:DQN65 RS12495
gene id: 38301:DQN65_RS12495
uniprot id: A0A2X4RHH3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

38301:DQN65 RS04675
gene id: 38301:DQN65_RS04675
uniprot id: A0A2X4RTP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

38301:DQN65 RS08390
gene id: 38301:DQN65_RS08390
uniprot id: A0A2X4RDS2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

38301:DQN65 RS06515
gene id: 38301:DQN65_RS06515
uniprot id: A0A2X4RDC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

38301:DQN65 RS08450
gene id: 38301:DQN65_RS08450
uniprot id: A0A2X4RN87
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

38301:DQN65 RS00805
gene id: 38301:DQN65_RS00805
uniprot id: A0A2X4R887
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

38301:DQN65 RS10910
gene id: 38301:DQN65_RS10910
uniprot id: A0A2X4RBV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS06060
gene id: 38301:DQN65_RS06060
uniprot id: A0A2X4RD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS10235
gene id: 38301:DQN65_RS10235
uniprot id: A0A2X4RFR4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

38301:DQN65 RS00990
gene id: 38301:DQN65_RS00990
uniprot id: A0A2X4U6W7
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS03760
gene id: 38301:DQN65_RS03760
uniprot id: A0A2X4RPS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

38301:DQN65 RS10550
gene id: 38301:DQN65_RS10550
uniprot id: A0A2X4RFH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

38301:DQN65 RS08110
gene id: 38301:DQN65_RS08110
uniprot id: A0A2X4RVL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

38301:DQN65 RS04745
gene id: 38301:DQN65_RS04745
uniprot id: A0A2X4UNS0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS09080
gene id: 38301:DQN65_RS09080
uniprot id: A0A2X4RAV8
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

38301:DQN65 RS00065
gene id: 38301:DQN65_RS00065
uniprot id: A0A2X4RG87
names: Similarity
messages: Belongs to the thioredoxin family.

38301:DQN65 RS12205
gene id: 38301:DQN65_RS12205
uniprot id: A0A2X4RQC8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

38301:DQN65 RS06715
gene id: 38301:DQN65_RS06715
uniprot id: A0A2X4RDG0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

38301:DQN65 RS10620
gene id: 38301:DQN65_RS10620
uniprot id: A0A2X4UE86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

38301:DQN65 RS00465
gene id: 38301:DQN65_RS00465
uniprot id: A0A2X4R7X1
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

38301:DQN65 RS09125
gene id: 38301:DQN65_RS09125
uniprot id: A0A2X4RE55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

38301:DQN65 RS02080
gene id: 38301:DQN65_RS02080
uniprot id: A0A2X4ULB5
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

38301:DQN65 RS05345
gene id: 38301:DQN65_RS05345
uniprot id: A0A2X4RU20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

38301:DQN65 RS04725
gene id: 38301:DQN65_RS04725
uniprot id: A0A2X4RTQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

38301:DQN65 RS12420
gene id: 38301:DQN65_RS12420
uniprot id: A0A2X4RY13
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00250
gene id: 38301:DQN65_RS00250
uniprot id: A0A2X4R7M2
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

38301:DQN65 RS09045
gene id: 38301:DQN65_RS09045
uniprot id: A0A2X4RW21
names: Similarity
messages: Belongs to the DEAD box helicase family.

38301:DQN65 RS07835
gene id: 38301:DQN65_RS07835
uniprot id: A0A2X4RAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS09210
gene id: 38301:DQN65_RS09210
uniprot id: A0A2X4RFE5
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

38301:DQN65 RS00550
gene id: 38301:DQN65_RS00550
uniprot id: A0A2X4U6E4
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

38301:DQN65 RS05945
gene id: 38301:DQN65_RS05945
uniprot id: A0A2X4RD78
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS08830
gene id: 38301:DQN65_RS08830
uniprot id: A0A2X4REM1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS06035
gene id: 38301:DQN65_RS06035
uniprot id: A0A2X4RCG6
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

38301:DQN65 RS09720
gene id: 38301:DQN65_RS09720
uniprot id: A0A2X4UDN9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

38301:DQN65 RS01655
gene id: 38301:DQN65_RS01655
uniprot id: A0A2X4R9G5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS05485
gene id: 38301:DQN65_RS05485
uniprot id: A0A2X4RLG7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

38301:DQN65 RS00350
gene id: 38301:DQN65_RS00350
uniprot id: A0A2X4U651
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS06615
gene id: 38301:DQN65_RS06615
uniprot id: A0A2X4RDD9
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

38301:DQN65 RS06745
gene id: 38301:DQN65_RS06745
uniprot id: A0A2X4R9N1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

38301:DQN65 RS09160
gene id: 38301:DQN65_RS09160
uniprot id: A0A2X4RFD1
names: Similarity
messages: Belongs to the thymidylate kinase family.

38301:DQN65 RS08285
gene id: 38301:DQN65_RS08285
uniprot id: A0A2X4UCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

38301:DQN65 RS10975
gene id: 38301:DQN65_RS10975
uniprot id: A0A2X4RX37
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS05400
gene id: 38301:DQN65_RS05400
uniprot id: A0A2X4RCQ8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

38301:DQN65 RS11530
gene id: 38301:DQN65_RS11530
uniprot id: A0A2X4RPY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS03770
gene id: 38301:DQN65_RS03770
uniprot id: A0A2X4RAW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

38301:DQN65 RS08865
gene id: 38301:DQN65_RS08865
uniprot id: A0A2X4RNG2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

38301:DQN65 RS01715
gene id: 38301:DQN65_RS01715
uniprot id: A0A2X4RQF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

38301:DQN65 RS06620
gene id: 38301:DQN65_RS06620
uniprot id: A0A2X4RS24
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02660
gene id: 38301:DQN65_RS02660
uniprot id: A0A2X4R9S5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

38301:DQN65 RS07820
gene id: 38301:DQN65_RS07820
uniprot id: A0A2X4UQD7
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

38301:DQN65 RS12370
gene id: 38301:DQN65_RS12370
uniprot id: A0A2X4RXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

38301:DQN65 RS04690
gene id: 38301:DQN65_RS04690
uniprot id: A0A2X4RCQ6
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS09995
gene id: 38301:DQN65_RS09995
uniprot id: A0A2X4RWK4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS10520
gene id: 38301:DQN65_RS10520
uniprot id: A0A2X4UE67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

38301:DQN65 RS02800
gene id: 38301:DQN65_RS02800
uniprot id: A0A2X4R6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS10025
gene id: 38301:DQN65_RS10025
uniprot id: A0A2X4REM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

38301:DQN65 RS01600
gene id: 38301:DQN65_RS01600
uniprot id: A0A2X4RHR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

38301:DQN65 RS09965
gene id: 38301:DQN65_RS09965
uniprot id: A0A2X4URH5
names: Similarity
messages: Belongs to the peptidase S11 family.

38301:DQN65 RS10080
gene id: 38301:DQN65_RS10080
uniprot id: A0A2X4RP27
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

38301:DQN65 RS00420
gene id: 38301:DQN65_RS00420
uniprot id: A0A2X4R7W2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

38301:DQN65 RS08090
gene id: 38301:DQN65_RS08090
uniprot id: A0A2X4RDL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

38301:DQN65 RS08240
gene id: 38301:DQN65_RS08240
uniprot id: A0A2X4RDP5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

38301:DQN65 RS00540
gene id: 38301:DQN65_RS00540
uniprot id: A0A2X4R8E1
names: Similarity
messages: Belongs to the UPF0371 family.

38301:DQN65 RS07110
gene id: 38301:DQN65_RS07110
uniprot id: A0A2X4RDP3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

38301:DQN65 RS09490
gene id: 38301:DQN65_RS09490
uniprot id: A0A2X4RNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

38301:DQN65 RS03775
gene id: 38301:DQN65_RS03775
uniprot id: A0A2X4RK08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

38301:DQN65 RS04530
gene id: 38301:DQN65_RS04530
uniprot id: A0A2X4R8L3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS09370
gene id: 38301:DQN65_RS09370
uniprot id: A0A2X4UDG4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

38301:DQN65 RS10605
gene id: 38301:DQN65_RS10605
uniprot id: A0A2X4RUD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

38301:DQN65 RS08485
gene id: 38301:DQN65_RS08485
uniprot id: A0A2X4UCZ3
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04495
gene id: 38301:DQN65_RS04495
uniprot id: A0A2X4RTI0
names: Similarity
messages: Belongs to the UPF0102 family.

38301:DQN65 RS11275
gene id: 38301:DQN65_RS11275
uniprot id: A0A2X4UEU8
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

38301:DQN65 RS05430
gene id: 38301:DQN65_RS05430
uniprot id: A0A2X4R910
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

38301:DQN65 RS05625
gene id: 38301:DQN65_RS05625
uniprot id: A0A2X4UB81
names: Similarity
messages: Belongs to the universal stress protein A family.

38301:DQN65 RS07295
gene id: 38301:DQN65_RS07295
uniprot id: A0A2X4RMM6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

38301:DQN65 RS06830
gene id: 38301:DQN65_RS06830
uniprot id: A0A2X4RDI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS10315
gene id: 38301:DQN65_RS10315
uniprot id: A0A2X4URN9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS04500
gene id: 38301:DQN65_RS04500
uniprot id: A0A2X4RC71
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

38301:DQN65 RS03020
gene id: 38301:DQN65_RS03020
uniprot id: A0A2X4RA44
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

38301:DQN65 RS00265
gene id: 38301:DQN65_RS00265
uniprot id: A0A2X4R8C7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

38301:DQN65 RS05560
gene id: 38301:DQN65_RS05560
uniprot id: A0A2X4RD86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS06955
gene id: 38301:DQN65_RS06955
uniprot id: A0A2X4RCZ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS10860
gene id: 38301:DQN65_RS10860
uniprot id: A0A2X4RBU5
names: Function
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
messages: Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).

38301:DQN65 RS07325
gene id: 38301:DQN65_RS07325
uniprot id: A0A2X4UQ37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS06210
gene id: 38301:DQN65_RS06210
uniprot id: A0A2X4RD61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

38301:DQN65 RS08145
gene id: 38301:DQN65_RS08145
uniprot id: A0A2X4RAF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

38301:DQN65 RS11055
gene id: 38301:DQN65_RS11055
uniprot id: A0A2X4RC06
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

38301:DQN65 RS04145
gene id: 38301:DQN65_RS04145
uniprot id: A0A2X4UA34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

38301:DQN65 RS10420
gene id: 38301:DQN65_RS10420
uniprot id: A0A2X4URQ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS02315
gene id: 38301:DQN65_RS02315
uniprot id: A0A2X4R9H9
names: Similarity
messages: Belongs to the peptidase S58 family.

38301:DQN65 RS09350
gene id: 38301:DQN65_RS09350
uniprot id: A0A2X4REW0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS03625
gene id: 38301:DQN65_RS03625
uniprot id: A0A2X4RAS1
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

38301:DQN65 RS09815
gene id: 38301:DQN65_RS09815
uniprot id: A0A2X4URE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS04680
gene id: 38301:DQN65_RS04680
uniprot id: A0A2X4RCC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

38301:DQN65 RS00035
gene id: 38301:DQN65_RS00035
uniprot id: A0A2X4UJF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

38301:DQN65 RS06635
gene id: 38301:DQN65_RS06635
uniprot id: A0A2X4UBS4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

38301:DQN65 RS09060
gene id: 38301:DQN65_RS09060
uniprot id: A0A2X4RFB1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

38301:DQN65 RS04825
gene id: 38301:DQN65_RS04825
uniprot id: A0A2X4RTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

38301:DQN65 RS00905
gene id: 38301:DQN65_RS00905
uniprot id: A0A2X4RM14
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

38301:DQN65 RS00725
gene id: 38301:DQN65_RS00725
uniprot id: A0A2X4R557
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

38301:DQN65 RS10480
gene id: 38301:DQN65_RS10480
uniprot id: A0A2X4RBM8
names: Similarity
messages: Belongs to the CFA/CMAS family.

38301:DQN65 RS06230
gene id: 38301:DQN65_RS06230
uniprot id: A0A2X4UBK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

38301:DQN65 RS02030
gene id: 38301:DQN65_RS02030
uniprot id: A0A2X4UL99
names: Caution
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lacks the conserved His residue that binds heme iron in the nitrobindin family.

38301:DQN65 RS02720
gene id: 38301:DQN65_RS02720
uniprot id: A0A2X4U8I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

38301:DQN65 RS01905
gene id: 38301:DQN65_RS01905
uniprot id: A0A2X4RMV4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

38301:DQN65 RS01870
gene id: 38301:DQN65_RS01870
uniprot id: A0A2X4R932
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07575
gene id: 38301:DQN65_RS07575
uniprot id: A0A2X4RA65
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

38301:DQN65 RS01485
gene id: 38301:DQN65_RS01485
uniprot id: A0A2X4RHN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

38301:DQN65 RS11875
gene id: 38301:DQN65_RS11875
uniprot id: A0A2X4UF86
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS07705
gene id: 38301:DQN65_RS07705
uniprot id: A0A2X4REJ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates zinc uptake. May also transport other divalent cations.
messages: Membrane

38301:DQN65 RS06520
gene id: 38301:DQN65_RS06520
uniprot id: A0A2X4RS04
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

38301:DQN65 RS00995
gene id: 38301:DQN65_RS00995
uniprot id: A0A2X4R5E5
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11940
gene id: 38301:DQN65_RS11940
uniprot id: A0A2X4RCK0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.
messages: Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.

38301:DQN65 RS11820
gene id: 38301:DQN65_RS11820
uniprot id: A0A2X4UF71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

38301:DQN65 RS03000
gene id: 38301:DQN65_RS03000
uniprot id: A0A2X4RNV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS08530
gene id: 38301:DQN65_RS08530
uniprot id: A0A2X4UQR7
names: Similarity
messages: Belongs to the FPG family.

38301:DQN65 RS00425
gene id: 38301:DQN65_RS00425
uniprot id: A0A2X4RGP9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

38301:DQN65 RS09840
gene id: 38301:DQN65_RS09840
uniprot id: A0A2X4RFH5
names: Similarity
messages: Belongs to the AccD/PCCB family.

38301:DQN65 RS09810
gene id: 38301:DQN65_RS09810
uniprot id: A0A2X4RFQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

38301:DQN65 RS07320
gene id: 38301:DQN65_RS07320
uniprot id: A0A2X4REB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

38301:DQN65 RS04150
gene id: 38301:DQN65_RS04150
uniprot id: A0A2X4R888
names: Similarity
messages: Belongs to the IMPACT family.

38301:DQN65 RS04835
gene id: 38301:DQN65_RS04835
uniprot id: A0A2X4RR02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

38301:DQN65 RS04885
gene id: 38301:DQN65_RS04885
uniprot id: A0A2X4RR13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS03095
gene id: 38301:DQN65_RS03095
uniprot id: A0A2X4R783
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

38301:DQN65 RS05830
gene id: 38301:DQN65_RS05830
uniprot id: A0A2X4RCC9
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

38301:DQN65 RS02050
gene id: 38301:DQN65_RS02050
uniprot id: A0A2X4R9V5
names: Similarity
messages: Belongs to the PstS family.

38301:DQN65 RS01280
gene id: 38301:DQN65_RS01280
uniprot id: A0A2X4R5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

38301:DQN65 RS04275
gene id: 38301:DQN65_RS04275
uniprot id: A0A2X4R8D6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

38301:DQN65 RS01075
gene id: 38301:DQN65_RS01075
uniprot id: A0A2X4R5G3
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS00210
gene id: 38301:DQN65_RS00210
uniprot id: A0A2X4RGE2
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS10175
gene id: 38301:DQN65_RS10175
uniprot id: A0A2X4RBG8
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

38301:DQN65 RS05310
gene id: 38301:DQN65_RS05310
uniprot id: A0A2X4RD35
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

38301:DQN65 RS01425
gene id: 38301:DQN65_RS01425
uniprot id: A0A2X4R8T5
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

38301:DQN65 RS07105
gene id: 38301:DQN65_RS07105
uniprot id: A0A2X4RV18
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

38301:DQN65 RS10895
gene id: 38301:DQN65_RS10895
uniprot id: A0A2X4US00
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

38301:DQN65 RS02190
gene id: 38301:DQN65_RS02190
uniprot id: A0A2X4R9D5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

38301:DQN65 RS12020
gene id: 38301:DQN65_RS12020
uniprot id: A0A2X4RGA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

38301:DQN65 RS06040
gene id: 38301:DQN65_RS06040
uniprot id: A0A2X4R9B6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

38301:DQN65 RS03875
gene id: 38301:DQN65_RS03875
uniprot id: A0A2X4RSU7
names: Similarity
messages: Belongs to the peptidase C40 family.

38301:DQN65 RS10960
gene id: 38301:DQN65_RS10960
uniprot id: A0A2X4RBX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS05355
gene id: 38301:DQN65_RS05355
uniprot id: A0A2X4RRB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

38301:DQN65 RS03790
gene id: 38301:DQN65_RS03790
uniprot id: A0A2X4UMZ1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

38301:DQN65 RS04445
gene id: 38301:DQN65_RS04445
uniprot id: A0A2X4RC70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

38301:DQN65 RS02620
gene id: 38301:DQN65_RS02620
uniprot id: A0A2X4RAH1
names: Similarity
messages: Belongs to the peptidase M1 family.

38301:DQN65 RS02410
gene id: 38301:DQN65_RS02410
uniprot id: A0A2X4RIJ5
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS04215
gene id: 38301:DQN65_RS04215
uniprot id: A0A2X4RQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

38301:DQN65 RS04770
gene id: 38301:DQN65_RS04770
uniprot id: A0A2X4RCH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

38301:DQN65 RS11790
gene id: 38301:DQN65_RS11790
uniprot id: A0A2X4RQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

38301:DQN65 RS11905
gene id: 38301:DQN65_RS11905
uniprot id: A0A2X4RG77
names: Similarity
messages: Belongs to the Nudix hydrolase family.

38301:DQN65 RS08135
gene id: 38301:DQN65_RS08135
uniprot id: A0A2X4UCR6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

38301:DQN65 RS09150
gene id: 38301:DQN65_RS09150
uniprot id: A0A2X4RES9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

38301:DQN65 RS02370
gene id: 38301:DQN65_RS02370
uniprot id: A0A2X4RR26
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

38301:DQN65 RS06885
gene id: 38301:DQN65_RS06885
uniprot id: A0A2X4RS76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

38301:DQN65 RS04180
gene id: 38301:DQN65_RS04180
uniprot id: A0A2X4RBW6
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

38301:DQN65 RS05010
gene id: 38301:DQN65_RS05010
uniprot id: A0A2X4R8V1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

38301:DQN65 RS05160
gene id: 38301:DQN65_RS05160
uniprot id: A0A2X4RCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

38301:DQN65 RS07195
gene id: 38301:DQN65_RS07195
uniprot id: A0A2X4RMK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

38301:DQN65 RS07780
gene id: 38301:DQN65_RS07780
uniprot id: A0A2X4RDG3
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS05365
gene id: 38301:DQN65_RS05365
uniprot id: A0A2X4UP31
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

38301:DQN65 RS03085
gene id: 38301:DQN65_RS03085
uniprot id: A0A2X4UMA6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

38301:DQN65 RS08680
gene id: 38301:DQN65_RS08680
uniprot id: A0A2X4UD39
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

38301:DQN65 RS03675
gene id: 38301:DQN65_RS03675
uniprot id: A0A2X4RPP4
names: Similarity
messages: Belongs to the glutamine synthetase family.

38301:DQN65 RS07685
gene id: 38301:DQN65_RS07685
uniprot id: A0A2X4REB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

38301:DQN65 RS08055
gene id: 38301:DQN65_RS08055
uniprot id: A0A2X4RVK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

38301:DQN65 RS05875
gene id: 38301:DQN65_RS05875
uniprot id: A0A2X4UBC4
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

38301:DQN65 RS02250
gene id: 38301:DQN65_RS02250
uniprot id: A0A2X4U814
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

38301:DQN65 RS12945
gene id: 38301:DQN65_RS12945
uniprot id: A0A2X4R9T4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

38301:DQN65 RS04580
gene id: 38301:DQN65_RS04580
uniprot id: A0A2X4RC90
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

38301:DQN65 RS02385
gene id: 38301:DQN65_RS02385
uniprot id: A0A2X4R9I0
names: Similarity
messages: Belongs to the peptidase S33 family.

38301:DQN65 RS12200
gene id: 38301:DQN65_RS12200
uniprot id: A0A2X4RCQ3
names: Similarity
messages: Belongs to the LOG family.

38301:DQN65 RS04525
gene id: 38301:DQN65_RS04525
uniprot id: A0A2X4RBL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

38301:DQN65 RS09175
gene id: 38301:DQN65_RS09175
uniprot id: A0A2X4RE63
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

38301:DQN65 RS09905
gene id: 38301:DQN65_RS09905
uniprot id: A0A2X4RTY3
names: Similarity
messages: Belongs to the citrate synthase family.

38301:DQN65 RS06080
gene id: 38301:DQN65_RS06080
uniprot id: A0A2X4UBG4
names: Subcellular Location Annotation
messages: Membrane

38301:DQN65 RS11060
gene id: 38301:DQN65_RS11060
uniprot id: A0A2X4RPL5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

38301:DQN65 RS09145
gene id: 38301:DQN65_RS09145
uniprot id: A0A2X4RW36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpqB lipoprotein family.
messages: Cell membrane

38301:DQN65 RS06260
gene id: 38301:DQN65_RS06260
uniprot id: A0A2X4RD71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

38301:DQN65 RS12045
gene id: 38301:DQN65_RS12045
uniprot id: A0A2X4RFU6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

38301:DQN65 RS04590
gene id: 38301:DQN65_RS04590
uniprot id: A0A2X4UAJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

38301:DQN65 RS01580
gene id: 38301:DQN65_RS01580
uniprot id: A0A2X4R9E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.