37928:AC20117 RS10890
gene id: 37928:AC20117_RS10890
uniprot id: A0A1H1B839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

37928:AC20117 RS11250
gene id: 37928:AC20117_RS11250
uniprot id: A0A1H1B325
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS11785
gene id: 37928:AC20117_RS11785
uniprot id: A0A1H1AWJ1
names: Similarity
messages: Belongs to the Dps family.

37928:AC20117 RS05640
gene id: 37928:AC20117_RS05640
uniprot id: A0A1H1DBY3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

37928:AC20117 RS09175
gene id: 37928:AC20117_RS09175
uniprot id: A0A1H1BY21
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

37928:AC20117 RS12530
gene id: 37928:AC20117_RS12530
uniprot id: A0A1H1AIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS21290
gene id: 37928:AC20117_RS21290
uniprot id: A0A1H1FR34
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

37928:AC20117 RS14010
gene id: 37928:AC20117_RS14010
uniprot id: A0A1H0ZZL3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13085
gene id: 37928:AC20117_RS13085
uniprot id: A0A1H1AB98
names: Similarity
messages: Belongs to the pirin family.

37928:AC20117 RS19230
gene id: 37928:AC20117_RS19230
uniprot id: A0A1H1GDE8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

37928:AC20117 RS07360
gene id: 37928:AC20117_RS07360
uniprot id: A0A1H1CN27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

37928:AC20117 RS16140
gene id: 37928:AC20117_RS16140
uniprot id: A0A1H0Z8Y4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS14150
gene id: 37928:AC20117_RS14150
uniprot id: A0A1H0ZXL2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09890
gene id: 37928:AC20117_RS09890
uniprot id: A0A1H1BN84
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

37928:AC20117 RS00495
gene id: 37928:AC20117_RS00495
uniprot id: A0A1H1FEF8
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

37928:AC20117 RS02845
gene id: 37928:AC20117_RS02845
uniprot id: A0A1H1EGN6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

37928:AC20117 RS07075
gene id: 37928:AC20117_RS07075
uniprot id: A0A1H1CS09
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

37928:AC20117 RS06435
gene id: 37928:AC20117_RS06435
uniprot id: A0A1H1D2E7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS04700
gene id: 37928:AC20117_RS04700
uniprot id: A0A1H1DR62
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

37928:AC20117 RS22590
gene id: 37928:AC20117_RS22590
uniprot id: A0A1H1HU65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS04735
gene id: 37928:AC20117_RS04735
uniprot id: A0A1H1DNW6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07335
gene id: 37928:AC20117_RS07335
uniprot id: A0A1H1CNC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

37928:AC20117 RS13605
gene id: 37928:AC20117_RS13605
uniprot id: A0A1H1A3T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS01775
gene id: 37928:AC20117_RS01775
uniprot id: A0A1H1EXE3
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS07950
gene id: 37928:AC20117_RS07950
uniprot id: A0A1H1CEI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

37928:AC20117 RS16905
gene id: 37928:AC20117_RS16905
uniprot id: A0A1H1H0R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

37928:AC20117 RS12170
gene id: 37928:AC20117_RS12170
uniprot id: A0A1H1APA7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS02200
gene id: 37928:AC20117_RS02200
uniprot id: A0A1H1ERT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

37928:AC20117 RS11445
gene id: 37928:AC20117_RS11445
uniprot id: A0A1H1AZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS16525
gene id: 37928:AC20117_RS16525
uniprot id: A0A1H1H457
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS15755
gene id: 37928:AC20117_RS15755
uniprot id: A0A1H0ZEE8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

37928:AC20117 RS19100
gene id: 37928:AC20117_RS19100
uniprot id: A0A1H1GFA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

37928:AC20117 RS01265
gene id: 37928:AC20117_RS01265
uniprot id: A0A1H1F4C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

37928:AC20117 RS11005
gene id: 37928:AC20117_RS11005
uniprot id: A0A1H1B6F9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13445
gene id: 37928:AC20117_RS13445
uniprot id: A0A1H1A5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

37928:AC20117 RS15795
gene id: 37928:AC20117_RS15795
uniprot id: A0A1H0ZD94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

37928:AC20117 RS06515
gene id: 37928:AC20117_RS06515
uniprot id: A0A1H1CZ97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS18935
gene id: 37928:AC20117_RS18935
uniprot id: A0A1H1GGT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

37928:AC20117 RS04910
gene id: 37928:AC20117_RS04910
uniprot id: A0A1H1DLN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS20655
gene id: 37928:AC20117_RS20655
uniprot id: A0A1H1FYM7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

37928:AC20117 RS21765
gene id: 37928:AC20117_RS21765
uniprot id: A0A1H1FKK6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

37928:AC20117 RS17765
gene id: 37928:AC20117_RS17765
uniprot id: A0A1H1GUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

37928:AC20117 RS20330
gene id: 37928:AC20117_RS20330
uniprot id: A0A1H1G258
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

37928:AC20117 RS00530
gene id: 37928:AC20117_RS00530
uniprot id: A0A1H1FE34
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

37928:AC20117 RS04065
gene id: 37928:AC20117_RS04065
uniprot id: A0A1H1DYI2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS10830
gene id: 37928:AC20117_RS10830
uniprot id: A0A1H1B901
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS11470
gene id: 37928:AC20117_RS11470
uniprot id: A0A1H1AZQ1
names: Similarity
messages: Belongs to the asparaginase 1 family.

37928:AC20117 RS08530
gene id: 37928:AC20117_RS08530
uniprot id: A0A1H1C6F8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

37928:AC20117 RS07685
gene id: 37928:AC20117_RS07685
uniprot id: A0A1H1CI89
names: Similarity
messages: Belongs to the peptidase S51 family.

37928:AC20117 RS12985
gene id: 37928:AC20117_RS12985
uniprot id: A0A1H1AC74
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS21650
gene id: 37928:AC20117_RS21650
uniprot id: A0A1H1FMH4
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

37928:AC20117 RS04710
gene id: 37928:AC20117_RS04710
uniprot id: A0A1H1DPA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

37928:AC20117 RS01535
gene id: 37928:AC20117_RS01535
uniprot id: A0A1H1F285
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

37928:AC20117 RS08610
gene id: 37928:AC20117_RS08610
uniprot id: A0A1H1C5Q4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19680
gene id: 37928:AC20117_RS19680
uniprot id: A0A1H1G9S1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18430
gene id: 37928:AC20117_RS18430
uniprot id: A0A1H1GMB8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

37928:AC20117 RS06920
gene id: 37928:AC20117_RS06920
uniprot id: A0A1H1CUC5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

37928:AC20117 RS14615
gene id: 37928:AC20117_RS14615
uniprot id: A0A1H0ZSC7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

37928:AC20117 RS06585
gene id: 37928:AC20117_RS06585
uniprot id: A0A1H1CZ74
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS20345
gene id: 37928:AC20117_RS20345
uniprot id: A0A1H1G1W3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

37928:AC20117 RS20495
gene id: 37928:AC20117_RS20495
uniprot id: A0A1H1G0I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

37928:AC20117 RS17085
gene id: 37928:AC20117_RS17085
uniprot id: A0A1H1GZ81
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

37928:AC20117 RS13150
gene id: 37928:AC20117_RS13150
uniprot id: A0A1H1AA30
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

37928:AC20117 RS13235
gene id: 37928:AC20117_RS13235
uniprot id: A0A1H1A996
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

37928:AC20117 RS19850
gene id: 37928:AC20117_RS19850
uniprot id: A0A1H1G7D9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

37928:AC20117 RS23400
gene id: 37928:AC20117_RS23400
uniprot id: A0A1H1GG51
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS19580
gene id: 37928:AC20117_RS19580
uniprot id: A0A1H1G9Z2
names: Similarity
messages: Belongs to the FPG family.

37928:AC20117 RS13440
gene id: 37928:AC20117_RS13440
uniprot id: A0A1H1A5X8
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

37928:AC20117 RS07765
gene id: 37928:AC20117_RS07765
uniprot id: A0A1H1CHC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

37928:AC20117 RS20305
gene id: 37928:AC20117_RS20305
uniprot id: A0A1H1G2F1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS14875
gene id: 37928:AC20117_RS14875
uniprot id: A0A1H0ZNR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

37928:AC20117 RS09330
gene id: 37928:AC20117_RS09330
uniprot id: A0A1H1BW69
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

37928:AC20117 RS04980
gene id: 37928:AC20117_RS04980
uniprot id: A0A1H1DKP5
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

37928:AC20117 RS07710
gene id: 37928:AC20117_RS07710
uniprot id: A0A1H1CI06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

37928:AC20117 RS18140
gene id: 37928:AC20117_RS18140
uniprot id: A0A1H1GQ68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

37928:AC20117 RS22335
gene id: 37928:AC20117_RS22335
uniprot id: A0A1H1HZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

37928:AC20117 RS08325
gene id: 37928:AC20117_RS08325
uniprot id: A0A1H1C9L3
names: Similarity
messages: Belongs to the group II decarboxylase family.

37928:AC20117 RS01625
gene id: 37928:AC20117_RS01625
uniprot id: A0A1H1EZC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

37928:AC20117 RS11345
gene id: 37928:AC20117_RS11345
uniprot id: A0A1H1B1T3
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

37928:AC20117 RS21815
gene id: 37928:AC20117_RS21815
uniprot id: A0A1H1FJR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

37928:AC20117 RS19890
gene id: 37928:AC20117_RS19890
uniprot id: A0A1H1G6T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

37928:AC20117 RS01510
gene id: 37928:AC20117_RS01510
uniprot id: A0A1H1F127
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

37928:AC20117 RS03395
gene id: 37928:AC20117_RS03395
uniprot id: A0A1H1E8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

37928:AC20117 RS20900
gene id: 37928:AC20117_RS20900
uniprot id: A0A1H1FWE1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18200
gene id: 37928:AC20117_RS18200
uniprot id: A0A1H1GPM5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07930
gene id: 37928:AC20117_RS07930
uniprot id: A0A1H1CF07
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

37928:AC20117 RS04815
gene id: 37928:AC20117_RS04815
uniprot id: A0A1H1DN33
names: Similarity
messages: Belongs to the CsoR family.

37928:AC20117 RS03175
gene id: 37928:AC20117_RS03175
uniprot id: A0A1H1EBU6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

37928:AC20117 RS04795
gene id: 37928:AC20117_RS04795
uniprot id: A0A1H1DMZ5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16650
gene id: 37928:AC20117_RS16650
uniprot id: A0A1H1H2W6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

37928:AC20117 RS17455
gene id: 37928:AC20117_RS17455
uniprot id: A0A1H1GVX7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

37928:AC20117 RS03790
gene id: 37928:AC20117_RS03790
uniprot id: A0A1H1E2D8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

37928:AC20117 RS10965
gene id: 37928:AC20117_RS10965
uniprot id: A0A1H1B762
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GcvT family.
messages: Cytoplasm

37928:AC20117 RS19820
gene id: 37928:AC20117_RS19820
uniprot id: A0A1H1G7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

37928:AC20117 RS07420
gene id: 37928:AC20117_RS07420
uniprot id: A0A1H1CM56
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

37928:AC20117 RS21675
gene id: 37928:AC20117_RS21675
uniprot id: A0A1H1FLV5
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

37928:AC20117 RS18805
gene id: 37928:AC20117_RS18805
uniprot id: A0A1H1GJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

37928:AC20117 RS02250
gene id: 37928:AC20117_RS02250
uniprot id: A0A1H1ER24
names: Similarity
messages: Belongs to the isochorismate synthase family.

37928:AC20117 RS20275
gene id: 37928:AC20117_RS20275
uniprot id: A0A1H1G2S0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS16380
gene id: 37928:AC20117_RS16380
uniprot id: A0A1H1H6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

37928:AC20117 RS19485
gene id: 37928:AC20117_RS19485
uniprot id: A0A1H1GB13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

37928:AC20117 RS01505
gene id: 37928:AC20117_RS01505
uniprot id: A0A1H1F1B0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

37928:AC20117 RS17855
gene id: 37928:AC20117_RS17855
uniprot id: A0A1H1GTI0
names: Similarity
messages: Belongs to the glutamate synthase family.

37928:AC20117 RS16205
gene id: 37928:AC20117_RS16205
uniprot id: A0A1H1H715
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

37928:AC20117 RS03795
gene id: 37928:AC20117_RS03795
uniprot id: A0A1H1E2E8
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS19220
gene id: 37928:AC20117_RS19220
uniprot id: A0A1H1GDF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

37928:AC20117 RS04725
gene id: 37928:AC20117_RS04725
uniprot id: A0A1H1DP88
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

37928:AC20117 RS21655
gene id: 37928:AC20117_RS21655
uniprot id: A0A1H1FMF0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

37928:AC20117 RS14490
gene id: 37928:AC20117_RS14490
uniprot id: A0A1H0ZT66
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS13820
gene id: 37928:AC20117_RS13820
uniprot id: A0A1H1A2F5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

37928:AC20117 RS04595
gene id: 37928:AC20117_RS04595
uniprot id: A0A1H1DQY6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00080
gene id: 37928:AC20117_RS00080
uniprot id: A0A1H1FIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

37928:AC20117 RS06790
gene id: 37928:AC20117_RS06790
uniprot id: A0A1H1CWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS18315
gene id: 37928:AC20117_RS18315
uniprot id: A0A1H1GND7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

37928:AC20117 RS18215
gene id: 37928:AC20117_RS18215
uniprot id: A0A1H1GPS1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

37928:AC20117 RS21865
gene id: 37928:AC20117_RS21865
uniprot id: A0A1H1FJJ9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

37928:AC20117 RS22885
gene id: 37928:AC20117_RS22885
uniprot id: A0A1H1HW35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS08865
gene id: 37928:AC20117_RS08865
uniprot id: A0A1H1C272
names: Similarity
messages: Belongs to the asparaginase 1 family.

37928:AC20117 RS18380
gene id: 37928:AC20117_RS18380
uniprot id: A0A1H1GMW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Belongs to the acyl-CoA oxidase family.

37928:AC20117 RS19240
gene id: 37928:AC20117_RS19240
uniprot id: A0A1H1GEB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

37928:AC20117 RS09035
gene id: 37928:AC20117_RS09035
uniprot id: A0A1H1C013
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS18865
gene id: 37928:AC20117_RS18865
uniprot id: A0A1H1GHN8
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

37928:AC20117 RS07055
gene id: 37928:AC20117_RS07055
uniprot id: A0A1H1CT47
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS10485
gene id: 37928:AC20117_RS10485
uniprot id: A0A1H1BEG2
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

37928:AC20117 RS06895
gene id: 37928:AC20117_RS06895
uniprot id: A0A1H1CVB6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

37928:AC20117 RS01315
gene id: 37928:AC20117_RS01315
uniprot id: A0A1H1F535
names: Similarity
messages: Belongs to the mannitol dehydrogenase family.

37928:AC20117 RS19480
gene id: 37928:AC20117_RS19480
uniprot id: A0A1H1GB87
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

37928:AC20117 RS06935
gene id: 37928:AC20117_RS06935
uniprot id: A0A1H1CUF0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16495
gene id: 37928:AC20117_RS16495
uniprot id: A0A1H1H4N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

37928:AC20117 RS03845
gene id: 37928:AC20117_RS03845
uniprot id: A0A1H1E1P6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

37928:AC20117 RS05160
gene id: 37928:AC20117_RS05160
uniprot id: A0A1H1DHS0
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

37928:AC20117 RS17920
gene id: 37928:AC20117_RS17920
uniprot id: A0A1H1GS95
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

37928:AC20117 RS19085
gene id: 37928:AC20117_RS19085
uniprot id: A0A1H1GF79
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

37928:AC20117 RS00415
gene id: 37928:AC20117_RS00415
uniprot id: A0A1H1FEZ2
names: Similarity
messages: Belongs to the peptidase S16 family.

37928:AC20117 RS02945
gene id: 37928:AC20117_RS02945
uniprot id: A0A1H1EF96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

37928:AC20117 RS03480
gene id: 37928:AC20117_RS03480
uniprot id: A0A1H1E7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS17005
gene id: 37928:AC20117_RS17005
uniprot id: A0A1H1H035
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

37928:AC20117 RS01175
gene id: 37928:AC20117_RS01175
uniprot id: A0A1H1F578
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

37928:AC20117 RS13460
gene id: 37928:AC20117_RS13460
uniprot id: A0A1H1A5Q4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

37928:AC20117 RS16810
gene id: 37928:AC20117_RS16810
uniprot id: A0A1H1H2R3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

37928:AC20117 RS20185
gene id: 37928:AC20117_RS20185
uniprot id: A0A1H1G3P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

37928:AC20117 RS09095
gene id: 37928:AC20117_RS09095
uniprot id: A0A1H1BZK7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

37928:AC20117 RS11835
gene id: 37928:AC20117_RS11835
uniprot id: A0A1H1AU38
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

37928:AC20117 RS03525
gene id: 37928:AC20117_RS03525
uniprot id: A0A1H1E6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

37928:AC20117 RS18135
gene id: 37928:AC20117_RS18135
uniprot id: A0A1H1GR42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

37928:AC20117 RS05795
gene id: 37928:AC20117_RS05795
uniprot id: A0A1H1D9E8
names: Similarity
messages: Belongs to the hyi family.

37928:AC20117 RS02380
gene id: 37928:AC20117_RS02380
uniprot id: A0A1H1EP71
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

37928:AC20117 RS07920
gene id: 37928:AC20117_RS07920
uniprot id: A0A1H1CEZ0
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

37928:AC20117 RS01790
gene id: 37928:AC20117_RS01790
uniprot id: A0A1H1EX79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

37928:AC20117 RS13590
gene id: 37928:AC20117_RS13590
uniprot id: A0A1H1A443
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS04495
gene id: 37928:AC20117_RS04495
uniprot id: A0A1H1DSD9
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

37928:AC20117 RS11030
gene id: 37928:AC20117_RS11030
uniprot id: A0A1H1B660
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS19930
gene id: 37928:AC20117_RS19930
uniprot id: A0A1H1G6A7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

37928:AC20117 RS20520
gene id: 37928:AC20117_RS20520
uniprot id: A0A1H1G089
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16785
gene id: 37928:AC20117_RS16785
uniprot id: A0A1H1H1S0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

37928:AC20117 RS01520
gene id: 37928:AC20117_RS01520
uniprot id: A0A1H1F0X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

37928:AC20117 RS07825
gene id: 37928:AC20117_RS07825
uniprot id: A0A1H1CG98
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

37928:AC20117 RS20030
gene id: 37928:AC20117_RS20030
uniprot id: A0A1H1G629
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

37928:AC20117 RS19865
gene id: 37928:AC20117_RS19865
uniprot id: A0A1H1G733
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

37928:AC20117 RS10950
gene id: 37928:AC20117_RS10950
uniprot id: A0A1H1B7F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS03485
gene id: 37928:AC20117_RS03485
uniprot id: A0A1H1E7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS00840
gene id: 37928:AC20117_RS00840
uniprot id: A0A1H1F986
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

37928:AC20117 RS17570
gene id: 37928:AC20117_RS17570
uniprot id: A0A1H1GUY8
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

37928:AC20117 RS16350
gene id: 37928:AC20117_RS16350
uniprot id: A0A1H1H5T6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

37928:AC20117 RS04400
gene id: 37928:AC20117_RS04400
uniprot id: A0A1H1DTQ9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16595
gene id: 37928:AC20117_RS16595
uniprot id: A0A1H1H4K5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

37928:AC20117 RS10785
gene id: 37928:AC20117_RS10785
uniprot id: A0A1H1B9Y9
names: Similarity
messages: Belongs to the peptidase C40 family.

37928:AC20117 RS03320
gene id: 37928:AC20117_RS03320
uniprot id: A0A1H1E9N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

37928:AC20117 RS04955
gene id: 37928:AC20117_RS04955
uniprot id: A0A1H1DL19
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16775
gene id: 37928:AC20117_RS16775
uniprot id: A0A1H1H322
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

37928:AC20117 RS09350
gene id: 37928:AC20117_RS09350
uniprot id: A0A1H1BVZ6
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS21805
gene id: 37928:AC20117_RS21805
uniprot id: A0A1H1FK73
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS20480
gene id: 37928:AC20117_RS20480
uniprot id: A0A1H1G1J4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

37928:AC20117 RS10940
gene id: 37928:AC20117_RS10940
uniprot id: A0A1H1B7B7
names: Similarity
messages: Belongs to the CdaR family.

37928:AC20117 RS11935
gene id: 37928:AC20117_RS11935
uniprot id: A0A1H1ASK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

37928:AC20117 RS00095
gene id: 37928:AC20117_RS00095
uniprot id: A0A1H1FIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

37928:AC20117 RS02270
gene id: 37928:AC20117_RS02270
uniprot id: A0A1H1EQA7
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS06155
gene id: 37928:AC20117_RS06155
uniprot id: A0A1H1D4G4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01460
gene id: 37928:AC20117_RS01460
uniprot id: A0A1H1F1U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

37928:AC20117 RS13295
gene id: 37928:AC20117_RS13295
uniprot id: A0A1H1A8E9
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

37928:AC20117 RS20315
gene id: 37928:AC20117_RS20315
uniprot id: A0A1H1G276
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

37928:AC20117 RS21570
gene id: 37928:AC20117_RS21570
uniprot id: A0A1H1FN34
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS11945
gene id: 37928:AC20117_RS11945
uniprot id: A0A1H1AST9
names: Subunit
messages: Homotetramer.

37928:AC20117 RS14670
gene id: 37928:AC20117_RS14670
uniprot id: A0A1H0ZR63
names: Similarity
messages: Belongs to the phosphohexose mutase family.

37928:AC20117 RS00820
gene id: 37928:AC20117_RS00820
uniprot id: A0A1H1F9Y2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

37928:AC20117 RS17075
gene id: 37928:AC20117_RS17075
uniprot id: A0A1H1GZH0
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

37928:AC20117 RS14915
gene id: 37928:AC20117_RS14915
uniprot id: A0A1H0ZMS0
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

37928:AC20117 RS06695
gene id: 37928:AC20117_RS06695
uniprot id: A0A1H1CX97
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS18795
gene id: 37928:AC20117_RS18795
uniprot id: A0A1H1GIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS05705
gene id: 37928:AC20117_RS05705
uniprot id: A0A1H1DAJ1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13290
gene id: 37928:AC20117_RS13290
uniprot id: A0A1H1A886
names: Similarity
messages: Belongs to the catalase family.

37928:AC20117 RS01730
gene id: 37928:AC20117_RS01730
uniprot id: A0A1H1EY63
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS17050
gene id: 37928:AC20117_RS17050
uniprot id: A0A1H1GZQ4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09450
gene id: 37928:AC20117_RS09450
uniprot id: A0A1H1BUL2
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

37928:AC20117 RS00010
gene id: 37928:AC20117_RS00010
uniprot id: A0A1H1FJR3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

37928:AC20117 RS13895
gene id: 37928:AC20117_RS13895
uniprot id: A0A1H1A0F9
names: Similarity
messages: Belongs to the peptidase A24 family.

37928:AC20117 RS00695
gene id: 37928:AC20117_RS00695
uniprot id: A0A1H1FBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS00945
gene id: 37928:AC20117_RS00945
uniprot id: A0A1H1F851
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

37928:AC20117 RS03130
gene id: 37928:AC20117_RS03130
uniprot id: A0A1H1ECC3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

37928:AC20117 RS08205
gene id: 37928:AC20117_RS08205
uniprot id: A0A1H1CB29
names: Similarity
messages: Belongs to the YciI family.

37928:AC20117 RS18850
gene id: 37928:AC20117_RS18850
uniprot id: A0A1H1GHU9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

37928:AC20117 RS08405
gene id: 37928:AC20117_RS08405
uniprot id: A0A1H1C8F2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS08310
gene id: 37928:AC20117_RS08310
uniprot id: A0A1H1C9X7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

37928:AC20117 RS11290
gene id: 37928:AC20117_RS11290
uniprot id: A0A1H1B2E7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17530
gene id: 37928:AC20117_RS17530
uniprot id: A0A1H1GVP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

37928:AC20117 RS02775
gene id: 37928:AC20117_RS02775
uniprot id: A0A1H1EHP7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

37928:AC20117 RS18685
gene id: 37928:AC20117_RS18685
uniprot id: A0A1H1GJB5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS13645
gene id: 37928:AC20117_RS13645
uniprot id: A0A1H1A390
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

37928:AC20117 RS15445
gene id: 37928:AC20117_RS15445
uniprot id: A0A1H0ZHY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

37928:AC20117 RS20120
gene id: 37928:AC20117_RS20120
uniprot id: A0A1H1G459
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

37928:AC20117 RS21900
gene id: 37928:AC20117_RS21900
uniprot id: A0A1H1FIJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

37928:AC20117 RS18075
gene id: 37928:AC20117_RS18075
uniprot id: A0A1H1GQT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. Tam family.
messages: Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
messages: Cytoplasm

37928:AC20117 RS06125
gene id: 37928:AC20117_RS06125
uniprot id: A0A1H1D6H3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS09985
gene id: 37928:AC20117_RS09985
uniprot id: A0A1H1BM00
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS19055
gene id: 37928:AC20117_RS19055
uniprot id: A0A1H1GFR7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

37928:AC20117 RS02875
gene id: 37928:AC20117_RS02875
uniprot id: A0A1H1EFY9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

37928:AC20117 RS10035
gene id: 37928:AC20117_RS10035
uniprot id: A0A1H1BKR0
names: Similarity
messages: Belongs to the manganese catalase family.

37928:AC20117 RS12475
gene id: 37928:AC20117_RS12475
uniprot id: A0A1H1AKH3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS15720
gene id: 37928:AC20117_RS15720
uniprot id: A0A1H0ZES9
names: Similarity
messages: Belongs to the peptidase S8 family.

37928:AC20117 RS14635
gene id: 37928:AC20117_RS14635
uniprot id: A0A1H0ZRQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

37928:AC20117 RS12880
gene id: 37928:AC20117_RS12880
uniprot id: A0A1H1AE01
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19475
gene id: 37928:AC20117_RS19475
uniprot id: A0A1H1GB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

37928:AC20117 RS01275
gene id: 37928:AC20117_RS01275
uniprot id: A0A1H1F5M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

37928:AC20117 RS04780
gene id: 37928:AC20117_RS04780
uniprot id: A0A1H1DNA3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17380
gene id: 37928:AC20117_RS17380
uniprot id: A0A1H1GWT3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

37928:AC20117 RS18475
gene id: 37928:AC20117_RS18475
uniprot id: A0A1H1GLM1
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS24175
gene id: 37928:AC20117_RS24175
uniprot id: A0A1H0ZKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS08330
gene id: 37928:AC20117_RS08330
uniprot id: A0A1H1C9E2
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

37928:AC20117 RS13545
gene id: 37928:AC20117_RS13545
uniprot id: A0A1H1A4K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

37928:AC20117 RS13385
gene id: 37928:AC20117_RS13385
uniprot id: A0A1H1A6I3
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

37928:AC20117 RS17300
gene id: 37928:AC20117_RS17300
uniprot id: A0A1H1GYF4
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS02150
gene id: 37928:AC20117_RS02150
uniprot id: A0A1H1ESN6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS03345
gene id: 37928:AC20117_RS03345
uniprot id: A0A1H1E9W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

37928:AC20117 RS12835
gene id: 37928:AC20117_RS12835
uniprot id: A0A1H1AEK7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

37928:AC20117 RS18975
gene id: 37928:AC20117_RS18975
uniprot id: A0A1H1GGL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

37928:AC20117 RS13915
gene id: 37928:AC20117_RS13915
uniprot id: A0A1H1A052
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

37928:AC20117 RS06105
gene id: 37928:AC20117_RS06105
uniprot id: A0A1H1D4T1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01395
gene id: 37928:AC20117_RS01395
uniprot id: A0A1H1F318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

37928:AC20117 RS03315
gene id: 37928:AC20117_RS03315
uniprot id: A0A1H1E9T4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

37928:AC20117 RS02560
gene id: 37928:AC20117_RS02560
uniprot id: A0A1H1EL90
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

37928:AC20117 RS16545
gene id: 37928:AC20117_RS16545
uniprot id: A0A1H1H3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

37928:AC20117 RS06340
gene id: 37928:AC20117_RS06340
uniprot id: A0A1H1D1T8
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

37928:AC20117 RS24130
gene id: 37928:AC20117_RS24130
uniprot id: A0A1H1ABN3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19925
gene id: 37928:AC20117_RS19925
uniprot id: A0A1H1G6A1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

37928:AC20117 RS03870
gene id: 37928:AC20117_RS03870
uniprot id: A0A1H1E1E5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06570
gene id: 37928:AC20117_RS06570
uniprot id: A0A1H1CYJ7
names: Similarity
messages: Belongs to the CdaR family.

37928:AC20117 RS00480
gene id: 37928:AC20117_RS00480
uniprot id: A0A1H1FEK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NlpA lipoprotein family.
messages: Membrane

37928:AC20117 RS06535
gene id: 37928:AC20117_RS06535
uniprot id: A0A1H1CZF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

37928:AC20117 RS16370
gene id: 37928:AC20117_RS16370
uniprot id: A0A1H1H6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

37928:AC20117 RS01450
gene id: 37928:AC20117_RS01450
uniprot id: A0A1H1F1V0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

37928:AC20117 RS16945
gene id: 37928:AC20117_RS16945
uniprot id: A0A1H1H0K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS01205
gene id: 37928:AC20117_RS01205
uniprot id: A0A1H1F528
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

37928:AC20117 RS01320
gene id: 37928:AC20117_RS01320
uniprot id: A0A1H1F3C8
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Membrane

37928:AC20117 RS18825
gene id: 37928:AC20117_RS18825
uniprot id: A0A1H1GHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

37928:AC20117 RS22185
gene id: 37928:AC20117_RS22185
uniprot id: A0A1H1HY75
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS22215
gene id: 37928:AC20117_RS22215
uniprot id: A0A1H1HZC5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS08090
gene id: 37928:AC20117_RS08090
uniprot id: A0A1H1CE36
names: Similarity
messages: Belongs to the UPF0045 family.

37928:AC20117 RS07465
gene id: 37928:AC20117_RS07465
uniprot id: A0A1H1CLE7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17025
gene id: 37928:AC20117_RS17025
uniprot id: A0A1H1H048
names: Similarity
messages: Belongs to the PrpD family.

37928:AC20117 RS18055
gene id: 37928:AC20117_RS18055
uniprot id: A0A1H1GQW5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS05000
gene id: 37928:AC20117_RS05000
uniprot id: A0A1H1DK49
names: Similarity
names: Subunit
messages: Belongs to the muconolactone Delta-isomerase family.
messages: Homodecamer.

37928:AC20117 RS15465
gene id: 37928:AC20117_RS15465
uniprot id: A0A1H0ZH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

37928:AC20117 RS20335
gene id: 37928:AC20117_RS20335
uniprot id: A0A1H1G238
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS20140
gene id: 37928:AC20117_RS20140
uniprot id: A0A1H1G3X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

37928:AC20117 RS18915
gene id: 37928:AC20117_RS18915
uniprot id: A0A1H1GH39
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

37928:AC20117 RS04825
gene id: 37928:AC20117_RS04825
uniprot id: A0A1H1DN80
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS11190
gene id: 37928:AC20117_RS11190
uniprot id: A0A1H1B400
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

37928:AC20117 RS02165
gene id: 37928:AC20117_RS02165
uniprot id: A0A1H1ESJ3
names: Similarity
messages: Belongs to the CdaR family.

37928:AC20117 RS05460
gene id: 37928:AC20117_RS05460
uniprot id: A0A1H1DDM5
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

37928:AC20117 RS22575
gene id: 37928:AC20117_RS22575
uniprot id: A0A1H1I0I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

37928:AC20117 RS21620
gene id: 37928:AC20117_RS21620
uniprot id: A0A1H1FMG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

37928:AC20117 RS11075
gene id: 37928:AC20117_RS11075
uniprot id: A0A1H1B5J4
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

37928:AC20117 RS10185
gene id: 37928:AC20117_RS10185
uniprot id: A0A1H1BIT1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

37928:AC20117 RS21885
gene id: 37928:AC20117_RS21885
uniprot id: A0A1H1FIW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

37928:AC20117 RS18660
gene id: 37928:AC20117_RS18660
uniprot id: A0A1H1GKM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

37928:AC20117 RS15595
gene id: 37928:AC20117_RS15595
uniprot id: A0A1H0ZFG0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

37928:AC20117 RS21360
gene id: 37928:AC20117_RS21360
uniprot id: A0A1H1FQ98
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS08465
gene id: 37928:AC20117_RS08465
uniprot id: A0A1H1C7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

37928:AC20117 RS16895
gene id: 37928:AC20117_RS16895
uniprot id: A0A1H1H204
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

37928:AC20117 RS05375
gene id: 37928:AC20117_RS05375
uniprot id: A0A1H1DES1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

37928:AC20117 RS06495
gene id: 37928:AC20117_RS06495
uniprot id: A0A1H1CZS2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS14365
gene id: 37928:AC20117_RS14365
uniprot id: A0A1H0ZV46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS19855
gene id: 37928:AC20117_RS19855
uniprot id: A0A1H1G7L3
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

37928:AC20117 RS18610
gene id: 37928:AC20117_RS18610
uniprot id: A0A1H1GL68
names: Similarity
names: Subunit
messages: Belongs to the AAA ATPase family.
messages: Homohexamer. Assembles into a hexameric ring structure.

37928:AC20117 RS14770
gene id: 37928:AC20117_RS14770
uniprot id: A0A1H0ZQ00
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS05555
gene id: 37928:AC20117_RS05555
uniprot id: A0A1H1DCK5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS22130
gene id: 37928:AC20117_RS22130
uniprot id: A0A1H1HXZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS17330
gene id: 37928:AC20117_RS17330
uniprot id: A0A1H1GXA3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

37928:AC20117 RS10695
gene id: 37928:AC20117_RS10695
uniprot id: A0A1H1BB77
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16935
gene id: 37928:AC20117_RS16935
uniprot id: A0A1H1H0S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS05450
gene id: 37928:AC20117_RS05450
uniprot id: A0A1H1DE14
names: Similarity
messages: Belongs to the DapA family.

37928:AC20117 RS16790
gene id: 37928:AC20117_RS16790
uniprot id: A0A1H1H228
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

37928:AC20117 RS16925
gene id: 37928:AC20117_RS16925
uniprot id: A0A1H1H0V3
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS10880
gene id: 37928:AC20117_RS10880
uniprot id: A0A1H1B8J4
names: Similarity
messages: Belongs to the GcvT family.

37928:AC20117 RS07110
gene id: 37928:AC20117_RS07110
uniprot id: A0A1H1CRM7
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

37928:AC20117 RS20605
gene id: 37928:AC20117_RS20605
uniprot id: A0A1H1FZ50
names: Similarity
messages: Belongs to the peptidase C40 family.

37928:AC20117 RS07810
gene id: 37928:AC20117_RS07810
uniprot id: A0A1H1CGP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

37928:AC20117 RS22290
gene id: 37928:AC20117_RS22290
uniprot id: A0A1H1HYS4
names: Similarity
messages: Belongs to the CsoR family.

37928:AC20117 RS17415
gene id: 37928:AC20117_RS17415
uniprot id: A0A1H1GWH7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

37928:AC20117 RS23875
gene id: 37928:AC20117_RS23875
uniprot id: A0A1H1ABA0
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

37928:AC20117 RS02295
gene id: 37928:AC20117_RS02295
uniprot id: A0A1H1ERQ2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19035
gene id: 37928:AC20117_RS19035
uniprot id: A0A1H1GFP4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS09345
gene id: 37928:AC20117_RS09345
uniprot id: A0A1H1BWF3
names: Similarity
messages: Belongs to the cytochrome P450 family.

37928:AC20117 RS14400
gene id: 37928:AC20117_RS14400
uniprot id: A0A1H0ZUE0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01670
gene id: 37928:AC20117_RS01670
uniprot id: A0A1H1EZF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

37928:AC20117 RS01500
gene id: 37928:AC20117_RS01500
uniprot id: A0A1H1F140
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

37928:AC20117 RS07980
gene id: 37928:AC20117_RS07980
uniprot id: A0A1H1CE39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

37928:AC20117 RS00490
gene id: 37928:AC20117_RS00490
uniprot id: A0A1H1FDK4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS01615
gene id: 37928:AC20117_RS01615
uniprot id: A0A1H1EZS8
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

37928:AC20117 RS22325
gene id: 37928:AC20117_RS22325
uniprot id: A0A1H1HZ58
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16190
gene id: 37928:AC20117_RS16190
uniprot id: A0A1H1H749
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

37928:AC20117 RS05825
gene id: 37928:AC20117_RS05825
uniprot id: A0A1H1D9R7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

37928:AC20117 RS01190
gene id: 37928:AC20117_RS01190
uniprot id: A0A1H1F508
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS02140
gene id: 37928:AC20117_RS02140
uniprot id: A0A1H1ESS8
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS18035
gene id: 37928:AC20117_RS18035
uniprot id: A0A1H1GR29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the UPF0157 (GrpB) family.
messages: In the N-terminal section; belongs to the CoaE family.

37928:AC20117 RS18405
gene id: 37928:AC20117_RS18405
uniprot id: A0A1H1GMT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

37928:AC20117 RS09770
gene id: 37928:AC20117_RS09770
uniprot id: A0A1H1BQ64
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

37928:AC20117 RS15405
gene id: 37928:AC20117_RS15405
uniprot id: A0A1H0ZHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

37928:AC20117 RS19775
gene id: 37928:AC20117_RS19775
uniprot id: A0A1H1G8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS05535
gene id: 37928:AC20117_RS05535
uniprot id: A0A1H1DEH1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06485
gene id: 37928:AC20117_RS06485
uniprot id: A0A1H1D0W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS04970
gene id: 37928:AC20117_RS04970
uniprot id: A0A1H1DKG4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS07905
gene id: 37928:AC20117_RS07905
uniprot id: A0A1H1CF92
names: Similarity
messages: Belongs to the PhoU family.

37928:AC20117 RS11135
gene id: 37928:AC20117_RS11135
uniprot id: A0A1H1B4I2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS16560
gene id: 37928:AC20117_RS16560
uniprot id: A0A1H1H461
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

37928:AC20117 RS05985
gene id: 37928:AC20117_RS05985
uniprot id: A0A1H1D6F1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00735
gene id: 37928:AC20117_RS00735
uniprot id: A0A1H1FBH3
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

37928:AC20117 RS05930
gene id: 37928:AC20117_RS05930
uniprot id: A0A1H1D958
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

37928:AC20117 RS11160
gene id: 37928:AC20117_RS11160
uniprot id: A0A1H1B469
names: Similarity
messages: Belongs to the UPF0225 family.

37928:AC20117 RS12065
gene id: 37928:AC20117_RS12065
uniprot id: A0A1H1AQY3
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS03805
gene id: 37928:AC20117_RS03805
uniprot id: A0A1H1E307
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS17345
gene id: 37928:AC20117_RS17345
uniprot id: A0A1H1GXA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS16695
gene id: 37928:AC20117_RS16695
uniprot id: A0A1H1H3R3
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.

37928:AC20117 RS08460
gene id: 37928:AC20117_RS08460
uniprot id: A0A1H1C7J5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

37928:AC20117 RS16325
gene id: 37928:AC20117_RS16325
uniprot id: A0A1H1H6W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

37928:AC20117 RS20410
gene id: 37928:AC20117_RS20410
uniprot id: A0A1H1G1B0
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS03095
gene id: 37928:AC20117_RS03095
uniprot id: A0A1H1ECV4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

37928:AC20117 RS17815
gene id: 37928:AC20117_RS17815
uniprot id: A0A1H1GTE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS08085
gene id: 37928:AC20117_RS08085
uniprot id: A0A1H1CCX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

37928:AC20117 RS16405
gene id: 37928:AC20117_RS16405
uniprot id: A0A1H1H576
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

37928:AC20117 RS01690
gene id: 37928:AC20117_RS01690
uniprot id: A0A1H1EYH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

37928:AC20117 RS16920
gene id: 37928:AC20117_RS16920
uniprot id: A0A1H1H0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

37928:AC20117 RS13570
gene id: 37928:AC20117_RS13570
uniprot id: A0A1H1A4E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS01310
gene id: 37928:AC20117_RS01310
uniprot id: A0A1H1F415
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

37928:AC20117 RS07780
gene id: 37928:AC20117_RS07780
uniprot id: A0A1H1CH26
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

37928:AC20117 RS15165
gene id: 37928:AC20117_RS15165
uniprot id: A0A1H0ZKC4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS02990
gene id: 37928:AC20117_RS02990
uniprot id: A0A1H1EF60
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS21835
gene id: 37928:AC20117_RS21835
uniprot id: A0A1H1FKD4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

37928:AC20117 RS18920
gene id: 37928:AC20117_RS18920
uniprot id: A0A1H1GGZ3
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

37928:AC20117 RS11280
gene id: 37928:AC20117_RS11280
uniprot id: A0A1H1B413
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS04625
gene id: 37928:AC20117_RS04625
uniprot id: A0A1H1DQD6
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS11540
gene id: 37928:AC20117_RS11540
uniprot id: A0A1H1AYP3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS08335
gene id: 37928:AC20117_RS08335
uniprot id: A0A1H1C9L6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

37928:AC20117 RS19505
gene id: 37928:AC20117_RS19505
uniprot id: A0A1H1GAX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

37928:AC20117 RS12095
gene id: 37928:AC20117_RS12095
uniprot id: A0A1H1AQA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS17475
gene id: 37928:AC20117_RS17475
uniprot id: A0A1H1GVY2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS21755
gene id: 37928:AC20117_RS21755
uniprot id: A0A1H1FLF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS01465
gene id: 37928:AC20117_RS01465
uniprot id: A0A1H1F376
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

37928:AC20117 RS16435
gene id: 37928:AC20117_RS16435
uniprot id: A0A1H1H522
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

37928:AC20117 RS17595
gene id: 37928:AC20117_RS17595
uniprot id: A0A1H1GUQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

37928:AC20117 RS01380
gene id: 37928:AC20117_RS01380
uniprot id: A0A1H1F2P4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS03105
gene id: 37928:AC20117_RS03105
uniprot id: A0A1H1EEI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

37928:AC20117 RS18120
gene id: 37928:AC20117_RS18120
uniprot id: A0A1H1GQD0
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

37928:AC20117 RS20050
gene id: 37928:AC20117_RS20050
uniprot id: A0A1H1G646
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS03140
gene id: 37928:AC20117_RS03140
uniprot id: A0A1H1ECA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell membrane

37928:AC20117 RS02160
gene id: 37928:AC20117_RS02160
uniprot id: A0A1H1ERY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

37928:AC20117 RS04025
gene id: 37928:AC20117_RS04025
uniprot id: A0A1H1E0Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS21850
gene id: 37928:AC20117_RS21850
uniprot id: A0A1H1FJQ7
names: Similarity
messages: Belongs to the DtxR/MntR family.

37928:AC20117 RS22695
gene id: 37928:AC20117_RS22695
uniprot id: A0A1H1HUS9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

37928:AC20117 RS22285
gene id: 37928:AC20117_RS22285
uniprot id: A0A1H1HZ61
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16195
gene id: 37928:AC20117_RS16195
uniprot id: A0A1H1H6Q1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

37928:AC20117 RS04835
gene id: 37928:AC20117_RS04835
uniprot id: A0A1H1DN30
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

37928:AC20117 RS12780
gene id: 37928:AC20117_RS12780
uniprot id: A0A1H1AFD0
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS02780
gene id: 37928:AC20117_RS02780
uniprot id: A0A1H1EIC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

37928:AC20117 RS04135
gene id: 37928:AC20117_RS04135
uniprot id: A0A1H1DY47
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS13580
gene id: 37928:AC20117_RS13580
uniprot id: A0A1H1A473
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

37928:AC20117 RS09440
gene id: 37928:AC20117_RS09440
uniprot id: A0A1H1BUL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

37928:AC20117 RS13115
gene id: 37928:AC20117_RS13115
uniprot id: A0A1H1AAD5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

37928:AC20117 RS21640
gene id: 37928:AC20117_RS21640
uniprot id: A0A1H1FMA6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

37928:AC20117 RS18410
gene id: 37928:AC20117_RS18410
uniprot id: A0A1H1GMI6
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.

37928:AC20117 RS08190
gene id: 37928:AC20117_RS08190
uniprot id: A0A1H1CB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS01455
gene id: 37928:AC20117_RS01455
uniprot id: A0A1H1F2A9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

37928:AC20117 RS05840
gene id: 37928:AC20117_RS05840
uniprot id: A0A1H1D9K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

37928:AC20117 RS13425
gene id: 37928:AC20117_RS13425
uniprot id: A0A1H1A699
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19295
gene id: 37928:AC20117_RS19295
uniprot id: A0A1H1GD15
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS01515
gene id: 37928:AC20117_RS01515
uniprot id: A0A1H1F0X0
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

37928:AC20117 RS19200
gene id: 37928:AC20117_RS19200
uniprot id: A0A1H1GE76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

37928:AC20117 RS11985
gene id: 37928:AC20117_RS11985
uniprot id: A0A1H1ARM7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17495
gene id: 37928:AC20117_RS17495
uniprot id: A0A1H1GWJ3
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

37928:AC20117 RS16365
gene id: 37928:AC20117_RS16365
uniprot id: A0A1H1H5R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

37928:AC20117 RS06210
gene id: 37928:AC20117_RS06210
uniprot id: A0A1H1D3B1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

37928:AC20117 RS00525
gene id: 37928:AC20117_RS00525
uniprot id: A0A1H1FE50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS09795
gene id: 37928:AC20117_RS09795
uniprot id: A0A1H1BRD1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS05070
gene id: 37928:AC20117_RS05070
uniprot id: A0A1H1DJB0
names: Similarity
messages: Belongs to the PspA/IM30 family.

37928:AC20117 RS19205
gene id: 37928:AC20117_RS19205
uniprot id: A0A1H1GE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

37928:AC20117 RS05415
gene id: 37928:AC20117_RS05415
uniprot id: A0A1H1DG34
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

37928:AC20117 RS18105
gene id: 37928:AC20117_RS18105
uniprot id: A0A1H1GRB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

37928:AC20117 RS18910
gene id: 37928:AC20117_RS18910
uniprot id: A0A1H1GI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

37928:AC20117 RS18950
gene id: 37928:AC20117_RS18950
uniprot id: A0A1H1GHG1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

37928:AC20117 RS19980
gene id: 37928:AC20117_RS19980
uniprot id: A0A1H1G5P5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

37928:AC20117 RS09830
gene id: 37928:AC20117_RS09830
uniprot id: A0A1H1BP84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

37928:AC20117 RS17265
gene id: 37928:AC20117_RS17265
uniprot id: A0A1H1GXV1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

37928:AC20117 RS08280
gene id: 37928:AC20117_RS08280
uniprot id: A0A1H1CAD7
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

37928:AC20117 RS15930
gene id: 37928:AC20117_RS15930
uniprot id: A0A1H0ZBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

37928:AC20117 RS00725
gene id: 37928:AC20117_RS00725
uniprot id: A0A1H1FB67
names: Similarity
messages: Belongs to the citrate synthase family.

37928:AC20117 RS01650
gene id: 37928:AC20117_RS01650
uniprot id: A0A1H1EZ68
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS03110
gene id: 37928:AC20117_RS03110
uniprot id: A0A1H1ECS9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

37928:AC20117 RS01710
gene id: 37928:AC20117_RS01710
uniprot id: A0A1H1EYF9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

37928:AC20117 RS01300
gene id: 37928:AC20117_RS01300
uniprot id: A0A1H1F5B1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

37928:AC20117 RS21635
gene id: 37928:AC20117_RS21635
uniprot id: A0A1H1FMT1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS08710
gene id: 37928:AC20117_RS08710
uniprot id: A0A1H1C475
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

37928:AC20117 RS18030
gene id: 37928:AC20117_RS18030
uniprot id: A0A1H1GR60
names: Similarity
messages: Belongs to the IMPACT family.

37928:AC20117 RS02685
gene id: 37928:AC20117_RS02685
uniprot id: A0A1H1EIQ9
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS19620
gene id: 37928:AC20117_RS19620
uniprot id: A0A1H1G9V1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

37928:AC20117 RS16930
gene id: 37928:AC20117_RS16930
uniprot id: A0A1H1H1Q3
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

37928:AC20117 RS14075
gene id: 37928:AC20117_RS14075
uniprot id: A0A1H0ZYB7
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

37928:AC20117 RS10600
gene id: 37928:AC20117_RS10600
uniprot id: A0A1H1BCP4
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

37928:AC20117 RS14790
gene id: 37928:AC20117_RS14790
uniprot id: A0A1H0ZPQ9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS11870
gene id: 37928:AC20117_RS11870
uniprot id: A0A1H1ATM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS19180
gene id: 37928:AC20117_RS19180
uniprot id: A0A1H1GF07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

37928:AC20117 RS13470
gene id: 37928:AC20117_RS13470
uniprot id: A0A1H1A5Y7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS03575
gene id: 37928:AC20117_RS03575
uniprot id: A0A1H1E6J5
names: Similarity
messages: Belongs to the acylphosphatase family.

37928:AC20117 RS18260
gene id: 37928:AC20117_RS18260
uniprot id: A0A1H1GPX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

37928:AC20117 RS12060
gene id: 37928:AC20117_RS12060
uniprot id: A0A1H1ARD9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS02615
gene id: 37928:AC20117_RS02615
uniprot id: A0A1H1EKG6
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

37928:AC20117 RS18270
gene id: 37928:AC20117_RS18270
uniprot id: A0A1H1GP70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS16470
gene id: 37928:AC20117_RS16470
uniprot id: A0A1H1H4W1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

37928:AC20117 RS06035
gene id: 37928:AC20117_RS06035
uniprot id: A0A1H1D5Z7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

37928:AC20117 RS18760
gene id: 37928:AC20117_RS18760
uniprot id: A0A1H1GIR6
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS08105
gene id: 37928:AC20117_RS08105
uniprot id: A0A1H1CCL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

37928:AC20117 RS02110
gene id: 37928:AC20117_RS02110
uniprot id: A0A1H1ESJ6
names: Similarity
messages: Belongs to the EccD/Snm4 family.

37928:AC20117 RS01560
gene id: 37928:AC20117_RS01560
uniprot id: A0A1H1F0D5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

37928:AC20117 RS08130
gene id: 37928:AC20117_RS08130
uniprot id: A0A1H1CC43
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS22970
gene id: 37928:AC20117_RS22970
uniprot id: A0A1H1HWL4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS16780
gene id: 37928:AC20117_RS16780
uniprot id: A0A1H1H215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

37928:AC20117 RS07435
gene id: 37928:AC20117_RS07435
uniprot id: A0A1H1CLW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

37928:AC20117 RS17745
gene id: 37928:AC20117_RS17745
uniprot id: A0A1H1GTI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

37928:AC20117 RS12800
gene id: 37928:AC20117_RS12800
uniprot id: A0A1H1AF93
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

37928:AC20117 RS01305
gene id: 37928:AC20117_RS01305
uniprot id: A0A1H1F3S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

37928:AC20117 RS07965
gene id: 37928:AC20117_RS07965
uniprot id: A0A1H1CFN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

37928:AC20117 RS17410
gene id: 37928:AC20117_RS17410
uniprot id: A0A1H1GXC4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

37928:AC20117 RS17395
gene id: 37928:AC20117_RS17395
uniprot id: A0A1H1GWK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

37928:AC20117 RS01950
gene id: 37928:AC20117_RS01950
uniprot id: A0A1H1EWM1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

37928:AC20117 RS03460
gene id: 37928:AC20117_RS03460
uniprot id: A0A1H1E8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

37928:AC20117 RS10735
gene id: 37928:AC20117_RS10735
uniprot id: A0A1H1BAL5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

37928:AC20117 RS05060
gene id: 37928:AC20117_RS05060
uniprot id: A0A1H1DJD3
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS19235
gene id: 37928:AC20117_RS19235
uniprot id: A0A1H1GEJ4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

37928:AC20117 RS13305
gene id: 37928:AC20117_RS13305
uniprot id: A0A1H1A7T0
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS06865
gene id: 37928:AC20117_RS06865
uniprot id: A0A1H1CV04
names: Similarity
messages: Belongs to the DprA/Smf family.

37928:AC20117 RS00195
gene id: 37928:AC20117_RS00195
uniprot id: A0A1H1FHK8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

37928:AC20117 RS15205
gene id: 37928:AC20117_RS15205
uniprot id: A0A1H0ZJU6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS16160
gene id: 37928:AC20117_RS16160
uniprot id: A0A1H0Z8W0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

37928:AC20117 RS13395
gene id: 37928:AC20117_RS13395
uniprot id: A0A1H1A6C8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS05270
gene id: 37928:AC20117_RS05270
uniprot id: A0A1H1DGB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS15275
gene id: 37928:AC20117_RS15275
uniprot id: A0A1H0ZIQ7
names: Similarity
messages: Belongs to the peptidase S8 family.

37928:AC20117 RS14235
gene id: 37928:AC20117_RS14235
uniprot id: A0A1H0ZWM2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

37928:AC20117 RS11425
gene id: 37928:AC20117_RS11425
uniprot id: A0A1H1B0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

37928:AC20117 RS07935
gene id: 37928:AC20117_RS07935
uniprot id: A0A1H1CF17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

37928:AC20117 RS10520
gene id: 37928:AC20117_RS10520
uniprot id: A0A1H1BDU8
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

37928:AC20117 RS16460
gene id: 37928:AC20117_RS16460
uniprot id: A0A1H1H4L7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

37928:AC20117 RS21685
gene id: 37928:AC20117_RS21685
uniprot id: A0A1H1FLP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

37928:AC20117 RS00220
gene id: 37928:AC20117_RS00220
uniprot id: A0A1H1FHG7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

37928:AC20117 RS05910
gene id: 37928:AC20117_RS05910
uniprot id: A0A1H1D7H3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS13930
gene id: 37928:AC20117_RS13930
uniprot id: A0A1H1A030
names: Similarity
messages: Belongs to the FBPase class 2 family.

37928:AC20117 RS17285
gene id: 37928:AC20117_RS17285
uniprot id: A0A1H1GXN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

37928:AC20117 RS08690
gene id: 37928:AC20117_RS08690
uniprot id: A0A1H1C4N9
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme modulates the balance between respiration and glycolysis, and contributes to redox homeostasis. Probably eliminates toxic levels of Cys (which can induce oxidative stress).
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

37928:AC20117 RS20040
gene id: 37928:AC20117_RS20040
uniprot id: A0A1H1G5Y2
names: Similarity
messages: Belongs to the P(II) protein family.

37928:AC20117 RS15045
gene id: 37928:AC20117_RS15045
uniprot id: A0A1H0ZL85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS08670
gene id: 37928:AC20117_RS08670
uniprot id: A0A1H1C4W5
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS04845
gene id: 37928:AC20117_RS04845
uniprot id: A0A1H1DMG6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

37928:AC20117 RS11025
gene id: 37928:AC20117_RS11025
uniprot id: A0A1H1B7P0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

37928:AC20117 RS14555
gene id: 37928:AC20117_RS14555
uniprot id: A0A1H0ZSX4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17185
gene id: 37928:AC20117_RS17185
uniprot id: A0A1H1GZE4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

37928:AC20117 RS08120
gene id: 37928:AC20117_RS08120
uniprot id: A0A1H1CCF9
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS10460
gene id: 37928:AC20117_RS10460
uniprot id: A0A1H1BF38
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS07890
gene id: 37928:AC20117_RS07890
uniprot id: A0A1H1CFE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

37928:AC20117 RS03040
gene id: 37928:AC20117_RS03040
uniprot id: A0A1H1EE24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS02655
gene id: 37928:AC20117_RS02655
uniprot id: A0A1H1EJE9
names: Similarity
messages: Belongs to the GSP E family.

37928:AC20117 RS16765
gene id: 37928:AC20117_RS16765
uniprot id: A0A1H1H360
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

37928:AC20117 RS09635
gene id: 37928:AC20117_RS09635
uniprot id: A0A1H1BTL8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09850
gene id: 37928:AC20117_RS09850
uniprot id: A0A1H1BNX4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS08635
gene id: 37928:AC20117_RS08635
uniprot id: A0A1H1C6P9
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS13585
gene id: 37928:AC20117_RS13585
uniprot id: A0A1H1A451
names: Similarity
messages: Belongs to the cytochrome P450 family.

37928:AC20117 RS13045
gene id: 37928:AC20117_RS13045
uniprot id: A0A1H1ABG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

37928:AC20117 RS10145
gene id: 37928:AC20117_RS10145
uniprot id: A0A1H1BJC0
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

37928:AC20117 RS01195
gene id: 37928:AC20117_RS01195
uniprot id: A0A1H1F5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

37928:AC20117 RS00970
gene id: 37928:AC20117_RS00970
uniprot id: A0A1H1F7X1
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

37928:AC20117 RS20170
gene id: 37928:AC20117_RS20170
uniprot id: A0A1H1G447
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

37928:AC20117 RS05275
gene id: 37928:AC20117_RS05275
uniprot id: A0A1H1DG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS15590
gene id: 37928:AC20117_RS15590
uniprot id: A0A1H0ZFN0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS10675
gene id: 37928:AC20117_RS10675
uniprot id: A0A1H1BBN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

37928:AC20117 RS17100
gene id: 37928:AC20117_RS17100
uniprot id: A0A1H1GZD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

37928:AC20117 RS09390
gene id: 37928:AC20117_RS09390
uniprot id: A0A1H1BWU8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS09940
gene id: 37928:AC20117_RS09940
uniprot id: A0A1H1BMD4
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

37928:AC20117 RS07955
gene id: 37928:AC20117_RS07955
uniprot id: A0A1H1CEF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

37928:AC20117 RS10710
gene id: 37928:AC20117_RS10710
uniprot id: A0A1H1BAW4
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

37928:AC20117 RS02050
gene id: 37928:AC20117_RS02050
uniprot id: A0A1H1EU31
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

37928:AC20117 RS02145
gene id: 37928:AC20117_RS02145
uniprot id: A0A1H1ES65
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS21615
gene id: 37928:AC20117_RS21615
uniprot id: A0A1H1FML3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

37928:AC20117 RS17390
gene id: 37928:AC20117_RS17390
uniprot id: A0A1H1GWQ4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

37928:AC20117 RS02980
gene id: 37928:AC20117_RS02980
uniprot id: A0A1H1EER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS20950
gene id: 37928:AC20117_RS20950
uniprot id: A0A1H1FV00
names: Similarity
messages: Belongs to the CsoR family.

37928:AC20117 RS10780
gene id: 37928:AC20117_RS10780
uniprot id: A0A1H1B9Y9
names: Similarity
messages: Belongs to the peptidase C40 family.

37928:AC20117 RS18690
gene id: 37928:AC20117_RS18690
uniprot id: A0A1H1GJH4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

37928:AC20117 RS13905
gene id: 37928:AC20117_RS13905
uniprot id: A0A1H1A0D3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19105
gene id: 37928:AC20117_RS19105
uniprot id: A0A1H1GEW6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

37928:AC20117 RS10750
gene id: 37928:AC20117_RS10750
uniprot id: A0A1H1BAA8
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS24165
gene id: 37928:AC20117_RS24165
uniprot id: A0A1H0ZZK8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

37928:AC20117 RS17470
gene id: 37928:AC20117_RS17470
uniprot id: A0A1H1GW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

37928:AC20117 RS17560
gene id: 37928:AC20117_RS17560
uniprot id: A0A1H1GV73
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00705
gene id: 37928:AC20117_RS00705
uniprot id: A0A1H1FBU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

37928:AC20117 RS15565
gene id: 37928:AC20117_RS15565
uniprot id: A0A1H0ZFS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

37928:AC20117 RS17460
gene id: 37928:AC20117_RS17460
uniprot id: A0A1H1GW37
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

37928:AC20117 RS05790
gene id: 37928:AC20117_RS05790
uniprot id: A0A1H1DB69
names: Similarity
messages: Belongs to the HIBADH-related family.

37928:AC20117 RS04245
gene id: 37928:AC20117_RS04245
uniprot id: A0A1H1DWM2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS03220
gene id: 37928:AC20117_RS03220
uniprot id: A0A1H1EBI5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

37928:AC20117 RS01125
gene id: 37928:AC20117_RS01125
uniprot id: A0A1H1F5V8
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

37928:AC20117 RS09505
gene id: 37928:AC20117_RS09505
uniprot id: A0A1H1BTP9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS16730
gene id: 37928:AC20117_RS16730
uniprot id: A0A1H1H2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

37928:AC20117 RS00770
gene id: 37928:AC20117_RS00770
uniprot id: A0A1H1FAJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS05875
gene id: 37928:AC20117_RS05875
uniprot id: A0A1H1D848
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS19420
gene id: 37928:AC20117_RS19420
uniprot id: A0A1H1GCB5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

37928:AC20117 RS14905
gene id: 37928:AC20117_RS14905
uniprot id: A0A1H0ZN11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS05320
gene id: 37928:AC20117_RS05320
uniprot id: A0A1H1DFJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.
messages: Homotrimer.

37928:AC20117 RS01905
gene id: 37928:AC20117_RS01905
uniprot id: A0A1H1EVP1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18895
gene id: 37928:AC20117_RS18895
uniprot id: A0A1H1GGX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

37928:AC20117 RS09955
gene id: 37928:AC20117_RS09955
uniprot id: A0A1H1BM67
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

37928:AC20117 RS00965
gene id: 37928:AC20117_RS00965
uniprot id: A0A1H1F7X2
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

37928:AC20117 RS12295
gene id: 37928:AC20117_RS12295
uniprot id: A0A1H1AM83
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS03850
gene id: 37928:AC20117_RS03850
uniprot id: A0A1H1E203
names: Similarity
messages: Belongs to the cytochrome P450 family.

37928:AC20117 RS21380
gene id: 37928:AC20117_RS21380
uniprot id: A0A1H1FR69
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

37928:AC20117 RS19875
gene id: 37928:AC20117_RS19875
uniprot id: A0A1H1G6X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

37928:AC20117 RS17790
gene id: 37928:AC20117_RS17790
uniprot id: A0A1H1GTM0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

37928:AC20117 RS00690
gene id: 37928:AC20117_RS00690
uniprot id: A0A1H1FBH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS21195
gene id: 37928:AC20117_RS21195
uniprot id: A0A1H1FS60
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

37928:AC20117 RS00475
gene id: 37928:AC20117_RS00475
uniprot id: A0A1H1FEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS20115
gene id: 37928:AC20117_RS20115
uniprot id: A0A1H1G4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AmiS/UreI family.
messages: Membrane

37928:AC20117 RS13780
gene id: 37928:AC20117_RS13780
uniprot id: A0A1H1A1Q3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS10125
gene id: 37928:AC20117_RS10125
uniprot id: A0A1H1BJR2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

37928:AC20117 RS04265
gene id: 37928:AC20117_RS04265
uniprot id: A0A1H1DVH5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS21820
gene id: 37928:AC20117_RS21820
uniprot id: A0A1H1FL98
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

37928:AC20117 RS19870
gene id: 37928:AC20117_RS19870
uniprot id: A0A1H1G7W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

37928:AC20117 RS16510
gene id: 37928:AC20117_RS16510
uniprot id: A0A1H1H5D6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

37928:AC20117 RS16890
gene id: 37928:AC20117_RS16890
uniprot id: A0A1H1H123
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

37928:AC20117 RS20245
gene id: 37928:AC20117_RS20245
uniprot id: A0A1H1G2W3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

37928:AC20117 RS00345
gene id: 37928:AC20117_RS00345
uniprot id: A0A1H1FFW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS12725
gene id: 37928:AC20117_RS12725
uniprot id: A0A1H1AGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS12445
gene id: 37928:AC20117_RS12445
uniprot id: A0A1H1AJW8
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

37928:AC20117 RS10085
gene id: 37928:AC20117_RS10085
uniprot id: A0A1H1BK06
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

37928:AC20117 RS15535
gene id: 37928:AC20117_RS15535
uniprot id: A0A1H0ZG64
names: Similarity
messages: Belongs to the hyi family.

37928:AC20117 RS06615
gene id: 37928:AC20117_RS06615
uniprot id: A0A1H1CZ71
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

37928:AC20117 RS19435
gene id: 37928:AC20117_RS19435
uniprot id: A0A1H1GBQ0
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

37928:AC20117 RS10360
gene id: 37928:AC20117_RS10360
uniprot id: A0A1H1BFL9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18505
gene id: 37928:AC20117_RS18505
uniprot id: A0A1H1GLI0
names: Subunit
messages: Homodimer.

37928:AC20117 RS19550
gene id: 37928:AC20117_RS19550
uniprot id: A0A1H1GA22
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

37928:AC20117 RS19070
gene id: 37928:AC20117_RS19070
uniprot id: A0A1H1GFA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

37928:AC20117 RS10860
gene id: 37928:AC20117_RS10860
uniprot id: A0A1H1B8T8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

37928:AC20117 RS10325
gene id: 37928:AC20117_RS10325
uniprot id: A0A1H1BGE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS19060
gene id: 37928:AC20117_RS19060
uniprot id: A0A1H1GFR4
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

37928:AC20117 RS05735
gene id: 37928:AC20117_RS05735
uniprot id: A0A1H1DA42
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

37928:AC20117 RS16330
gene id: 37928:AC20117_RS16330
uniprot id: A0A1H1H617
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18625
gene id: 37928:AC20117_RS18625
uniprot id: A0A1H1GKA9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

37928:AC20117 RS00090
gene id: 37928:AC20117_RS00090
uniprot id: A0A1H1FKE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

37928:AC20117 RS18585
gene id: 37928:AC20117_RS18585
uniprot id: A0A1H1GKF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

37928:AC20117 RS01675
gene id: 37928:AC20117_RS01675
uniprot id: A0A1H1EZ89
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

37928:AC20117 RS22505
gene id: 37928:AC20117_RS22505
uniprot id: A0A1H1HZZ8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS13935
gene id: 37928:AC20117_RS13935
uniprot id: A0A1H1A047
names: Similarity
messages: Belongs to the FemABX family.

37928:AC20117 RS20180
gene id: 37928:AC20117_RS20180
uniprot id: A0A1H1G4G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

37928:AC20117 RS10690
gene id: 37928:AC20117_RS10690
uniprot id: A0A1H1BBE8
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS00560
gene id: 37928:AC20117_RS00560
uniprot id: A0A1H1FDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

37928:AC20117 RS08255
gene id: 37928:AC20117_RS08255
uniprot id: A0A1H1CAC1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17270
gene id: 37928:AC20117_RS17270
uniprot id: A0A1H1GXN8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

37928:AC20117 RS03760
gene id: 37928:AC20117_RS03760
uniprot id: A0A1H1E391
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS21230
gene id: 37928:AC20117_RS21230
uniprot id: A0A1H1FRR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS03820
gene id: 37928:AC20117_RS03820
uniprot id: A0A1H1E2A3
names: Similarity
messages: Belongs to the UPF0311 family.

37928:AC20117 RS16745
gene id: 37928:AC20117_RS16745
uniprot id: A0A1H1H3B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS04900
gene id: 37928:AC20117_RS04900
uniprot id: A0A1H1DLL6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

37928:AC20117 RS08765
gene id: 37928:AC20117_RS08765
uniprot id: A0A1H1C3K0
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS00015
gene id: 37928:AC20117_RS00015
uniprot id: A0A1H1FL98
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

37928:AC20117 RS09260
gene id: 37928:AC20117_RS09260
uniprot id: A0A1H1BXH1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

37928:AC20117 RS20295
gene id: 37928:AC20117_RS20295
uniprot id: A0A1H1G2J3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

37928:AC20117 RS01590
gene id: 37928:AC20117_RS01590
uniprot id: A0A1H1F0G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

37928:AC20117 RS08480
gene id: 37928:AC20117_RS08480
uniprot id: A0A1H1C740
names: Similarity
messages: Belongs to the peptidase S8 family.

37928:AC20117 RS04705
gene id: 37928:AC20117_RS04705
uniprot id: A0A1H1DP68
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

37928:AC20117 RS19130
gene id: 37928:AC20117_RS19130
uniprot id: A0A1H1GEP6
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

37928:AC20117 RS13940
gene id: 37928:AC20117_RS13940
uniprot id: A0A1H1A015
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

37928:AC20117 RS07740
gene id: 37928:AC20117_RS07740
uniprot id: A0A1H1CHN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

37928:AC20117 RS10815
gene id: 37928:AC20117_RS10815
uniprot id: A0A1H1B967
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

37928:AC20117 RS18230
gene id: 37928:AC20117_RS18230
uniprot id: A0A1H1GPL2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

37928:AC20117 RS03355
gene id: 37928:AC20117_RS03355
uniprot id: A0A1H1E9F3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01995
gene id: 37928:AC20117_RS01995
uniprot id: A0A1H1EUC0
names: Similarity
messages: Belongs to the UPF0234 family.

37928:AC20117 RS18050
gene id: 37928:AC20117_RS18050
uniprot id: A0A1H1GR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

37928:AC20117 RS16505
gene id: 37928:AC20117_RS16505
uniprot id: A0A1H1H4K7
names: Similarity
messages: Belongs to the YciI family.

37928:AC20117 RS05465
gene id: 37928:AC20117_RS05465
uniprot id: A0A1H1DFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS16835
gene id: 37928:AC20117_RS16835
uniprot id: A0A1H1H1D0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

37928:AC20117 RS05855
gene id: 37928:AC20117_RS05855
uniprot id: A0A1H1D8D8
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

37928:AC20117 RS17275
gene id: 37928:AC20117_RS17275
uniprot id: A0A1H1GXL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

37928:AC20117 RS20045
gene id: 37928:AC20117_RS20045
uniprot id: A0A1H1G4Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS05895
gene id: 37928:AC20117_RS05895
uniprot id: A0A1H1D7U4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS05720
gene id: 37928:AC20117_RS05720
uniprot id: A0A1H1DAH0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00755
gene id: 37928:AC20117_RS00755
uniprot id: A0A1H1FAM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

37928:AC20117 RS08515
gene id: 37928:AC20117_RS08515
uniprot id: A0A1H1C6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS13800
gene id: 37928:AC20117_RS13800
uniprot id: A0A1H1A1K6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

37928:AC20117 RS07425
gene id: 37928:AC20117_RS07425
uniprot id: A0A1H1CMF2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS20915
gene id: 37928:AC20117_RS20915
uniprot id: A0A1H1FVB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

37928:AC20117 RS14980
gene id: 37928:AC20117_RS14980
uniprot id: A0A1H0ZNB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

37928:AC20117 RS09700
gene id: 37928:AC20117_RS09700
uniprot id: A0A1H1BSM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

37928:AC20117 RS17080
gene id: 37928:AC20117_RS17080
uniprot id: A0A1H1GZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

37928:AC20117 RS21600
gene id: 37928:AC20117_RS21600
uniprot id: A0A1H1FMS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

37928:AC20117 RS01470
gene id: 37928:AC20117_RS01470
uniprot id: A0A1H1F1H7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

37928:AC20117 RS07025
gene id: 37928:AC20117_RS07025
uniprot id: A0A1H1CTK7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS02575
gene id: 37928:AC20117_RS02575
uniprot id: A0A1H1EKY9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS20740
gene id: 37928:AC20117_RS20740
uniprot id: A0A1H1FXL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

37928:AC20117 RS17130
gene id: 37928:AC20117_RS17130
uniprot id: A0A1H1GZ33
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

37928:AC20117 RS17805
gene id: 37928:AC20117_RS17805
uniprot id: A0A1H1GTY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

37928:AC20117 RS13635
gene id: 37928:AC20117_RS13635
uniprot id: A0A1H1A3G5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13660
gene id: 37928:AC20117_RS13660
uniprot id: A0A1H1A3A0
names: Similarity
messages: Belongs to the cytochrome b560 family.

37928:AC20117 RS06505
gene id: 37928:AC20117_RS06505
uniprot id: A0A1H1CZK6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01795
gene id: 37928:AC20117_RS01795
uniprot id: A0A1H1EYS0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

37928:AC20117 RS17845
gene id: 37928:AC20117_RS17845
uniprot id: A0A1H1GSS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

37928:AC20117 RS02985
gene id: 37928:AC20117_RS02985
uniprot id: A0A1H1EG54
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16465
gene id: 37928:AC20117_RS16465
uniprot id: A0A1H1H4Q0
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

37928:AC20117 RS16315
gene id: 37928:AC20117_RS16315
uniprot id: A0A1H1H621
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

37928:AC20117 RS08890
gene id: 37928:AC20117_RS08890
uniprot id: A0A1H1C1X0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

37928:AC20117 RS02005
gene id: 37928:AC20117_RS02005
uniprot id: A0A1H1EU89
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS16860
gene id: 37928:AC20117_RS16860
uniprot id: A0A1H1H2C5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

37928:AC20117 RS04200
gene id: 37928:AC20117_RS04200
uniprot id: A0A1H1DWL9
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

37928:AC20117 RS05440
gene id: 37928:AC20117_RS05440
uniprot id: A0A1H1DDX0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

37928:AC20117 RS08685
gene id: 37928:AC20117_RS08685
uniprot id: A0A1H1C4J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

37928:AC20117 RS00135
gene id: 37928:AC20117_RS00135
uniprot id: A0A1H1FJ73
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09180
gene id: 37928:AC20117_RS09180
uniprot id: A0A1H1BY22
names: Similarity
messages: Belongs to the FPG family.

37928:AC20117 RS19430
gene id: 37928:AC20117_RS19430
uniprot id: A0A1H1GCJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

37928:AC20117 RS20590
gene id: 37928:AC20117_RS20590
uniprot id: A0A1H1G0B2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS21715
gene id: 37928:AC20117_RS21715
uniprot id: A0A1H1FLE5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00795
gene id: 37928:AC20117_RS00795
uniprot id: A0A1H1FA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS12915
gene id: 37928:AC20117_RS12915
uniprot id: A0A1H1ADG6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

37928:AC20117 RS17325
gene id: 37928:AC20117_RS17325
uniprot id: A0A1H1GXD2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

37928:AC20117 RS22205
gene id: 37928:AC20117_RS22205
uniprot id: A0A1H1HZC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

37928:AC20117 RS19685
gene id: 37928:AC20117_RS19685
uniprot id: A0A1H1G9Q3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

37928:AC20117 RS04820
gene id: 37928:AC20117_RS04820
uniprot id: A0A1H1DPH4
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

37928:AC20117 RS22320
gene id: 37928:AC20117_RS22320
uniprot id: A0A1H1HYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

37928:AC20117 RS09820
gene id: 37928:AC20117_RS09820
uniprot id: A0A1H1BPG3
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

37928:AC20117 RS02645
gene id: 37928:AC20117_RS02645
uniprot id: A0A1H1EK54
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07365
gene id: 37928:AC20117_RS07365
uniprot id: A0A1H1CMU1
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

37928:AC20117 RS04565
gene id: 37928:AC20117_RS04565
uniprot id: A0A1H1DS14
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS22585
gene id: 37928:AC20117_RS22585
uniprot id: A0A1H1HTZ3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS23885
gene id: 37928:AC20117_RS23885
uniprot id: A0A1H1A200
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

37928:AC20117 RS16360
gene id: 37928:AC20117_RS16360
uniprot id: A0A1H1H5G0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS17360
gene id: 37928:AC20117_RS17360
uniprot id: A0A1H1GX42
names: Similarity
messages: Belongs to the glutamine synthetase family.

37928:AC20117 RS08025
gene id: 37928:AC20117_RS08025
uniprot id: A0A1H1CDL3
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

37928:AC20117 RS06465
gene id: 37928:AC20117_RS06465
uniprot id: A0A1H1D062
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

37928:AC20117 RS21680
gene id: 37928:AC20117_RS21680
uniprot id: A0A1H1FMU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

37928:AC20117 RS19215
gene id: 37928:AC20117_RS19215
uniprot id: A0A1H1GDH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

37928:AC20117 RS01155
gene id: 37928:AC20117_RS01155
uniprot id: A0A1H1F5Q0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09610
gene id: 37928:AC20117_RS09610
uniprot id: A0A1H1BSI5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS20530
gene id: 37928:AC20117_RS20530
uniprot id: A0A1H1G034
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS19065
gene id: 37928:AC20117_RS19065
uniprot id: A0A1H1GF38
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

37928:AC20117 RS03045
gene id: 37928:AC20117_RS03045
uniprot id: A0A1H1EE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS06085
gene id: 37928:AC20117_RS06085
uniprot id: A0A1H1D599
names: Caution
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS10380
gene id: 37928:AC20117_RS10380
uniprot id: A0A1H1BFC9
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

37928:AC20117 RS15240
gene id: 37928:AC20117_RS15240
uniprot id: A0A1H0ZJ65
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

37928:AC20117 RS00870
gene id: 37928:AC20117_RS00870
uniprot id: A0A1H1F8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS19860
gene id: 37928:AC20117_RS19860
uniprot id: A0A1H1G7J3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

37928:AC20117 RS13805
gene id: 37928:AC20117_RS13805
uniprot id: A0A1H1A1C3
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

37928:AC20117 RS05525
gene id: 37928:AC20117_RS05525
uniprot id: A0A1H1DCQ0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16175
gene id: 37928:AC20117_RS16175
uniprot id: A0A1H1H793
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

37928:AC20117 RS18250
gene id: 37928:AC20117_RS18250
uniprot id: A0A1H1GP94
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS03780
gene id: 37928:AC20117_RS03780
uniprot id: A0A1H1E300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS13710
gene id: 37928:AC20117_RS13710
uniprot id: A0A1H1A321
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

37928:AC20117 RS07900
gene id: 37928:AC20117_RS07900
uniprot id: A0A1H1CFL0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07870
gene id: 37928:AC20117_RS07870
uniprot id: A0A1H1CFQ3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

37928:AC20117 RS21750
gene id: 37928:AC20117_RS21750
uniprot id: A0A1H1FL61
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

37928:AC20117 RS09900
gene id: 37928:AC20117_RS09900
uniprot id: A0A1H1BND3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

37928:AC20117 RS06410
gene id: 37928:AC20117_RS06410
uniprot id: A0A1H1D107
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

37928:AC20117 RS08015
gene id: 37928:AC20117_RS08015
uniprot id: A0A1H1CDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

37928:AC20117 RS17780
gene id: 37928:AC20117_RS17780
uniprot id: A0A1H1GTF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

37928:AC20117 RS04655
gene id: 37928:AC20117_RS04655
uniprot id: A0A1H1DRU3
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

37928:AC20117 RS18245
gene id: 37928:AC20117_RS18245
uniprot id: A0A1H1GP50
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16110
gene id: 37928:AC20117_RS16110
uniprot id: A0A1H0Z9H4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

37928:AC20117 RS00600
gene id: 37928:AC20117_RS00600
uniprot id: A0A1H1FCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

37928:AC20117 RS03390
gene id: 37928:AC20117_RS03390
uniprot id: A0A1H1E8L2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

37928:AC20117 RS10935
gene id: 37928:AC20117_RS10935
uniprot id: A0A1H1B7K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

37928:AC20117 RS12355
gene id: 37928:AC20117_RS12355
uniprot id: A0A1H1ALK1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS21595
gene id: 37928:AC20117_RS21595
uniprot id: A0A1H1FMU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

37928:AC20117 RS04115
gene id: 37928:AC20117_RS04115
uniprot id: A0A1H1DXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

37928:AC20117 RS04420
gene id: 37928:AC20117_RS04420
uniprot id: A0A1H1DTJ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS02905
gene id: 37928:AC20117_RS02905
uniprot id: A0A1H1EGD7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

37928:AC20117 RS07990
gene id: 37928:AC20117_RS07990
uniprot id: A0A1H1CFC2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17365
gene id: 37928:AC20117_RS17365
uniprot id: A0A1H1GWU5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06480
gene id: 37928:AC20117_RS06480
uniprot id: A0A1H1CZQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS14990
gene id: 37928:AC20117_RS14990
uniprot id: A0A1H0ZN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS00105
gene id: 37928:AC20117_RS00105
uniprot id: A0A1H1FIW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

37928:AC20117 RS19545
gene id: 37928:AC20117_RS19545
uniprot id: A0A1H1GB35
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

37928:AC20117 RS22225
gene id: 37928:AC20117_RS22225
uniprot id: A0A1H1HYK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

37928:AC20117 RS13540
gene id: 37928:AC20117_RS13540
uniprot id: A0A1H1A4P6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS19030
gene id: 37928:AC20117_RS19030
uniprot id: A0A1H1GFG6
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

37928:AC20117 RS16520
gene id: 37928:AC20117_RS16520
uniprot id: A0A1H1H4C5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS19800
gene id: 37928:AC20117_RS19800
uniprot id: A0A1H1G7L1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

37928:AC20117 RS12270
gene id: 37928:AC20117_RS12270
uniprot id: A0A1H1AMP3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS12930
gene id: 37928:AC20117_RS12930
uniprot id: A0A1H1AD09
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS01800
gene id: 37928:AC20117_RS01800
uniprot id: A0A1H1EX01
names: Similarity
messages: Belongs to the Nudix hydrolase family.

37928:AC20117 RS00765
gene id: 37928:AC20117_RS00765
uniprot id: A0A1H1FAL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS21780
gene id: 37928:AC20117_RS21780
uniprot id: A0A1H1FK41
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

37928:AC20117 RS22210
gene id: 37928:AC20117_RS22210
uniprot id: A0A1H1HZB8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS21610
gene id: 37928:AC20117_RS21610
uniprot id: A0A1H1FMM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

37928:AC20117 RS02870
gene id: 37928:AC20117_RS02870
uniprot id: A0A1H1EG85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

37928:AC20117 RS05775
gene id: 37928:AC20117_RS05775
uniprot id: A0A1H1D9M7
names: Subunit
messages: Homotetramer.

37928:AC20117 RS15885
gene id: 37928:AC20117_RS15885
uniprot id: A0A1H0ZC03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Cleaves guanosine, inosine, 2'-deoxyguanosine and 2'-deoxyinosine.

37928:AC20117 RS06880
gene id: 37928:AC20117_RS06880
uniprot id: A0A1H1CUY2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

37928:AC20117 RS16740
gene id: 37928:AC20117_RS16740
uniprot id: A0A1H1H2E7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

37928:AC20117 RS19140
gene id: 37928:AC20117_RS19140
uniprot id: A0A1H1GEU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS10870
gene id: 37928:AC20117_RS10870
uniprot id: A0A1H1B8I6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS11875
gene id: 37928:AC20117_RS11875
uniprot id: A0A1H1ATL0
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS03600
gene id: 37928:AC20117_RS03600
uniprot id: A0A1H1E5K1
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS01495
gene id: 37928:AC20117_RS01495
uniprot id: A0A1H1F185
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

37928:AC20117 RS04385
gene id: 37928:AC20117_RS04385
uniprot id: A0A1H1DTY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

37928:AC20117 RS19600
gene id: 37928:AC20117_RS19600
uniprot id: A0A1H1G9S2
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS06285
gene id: 37928:AC20117_RS06285
uniprot id: A0A1H1D310
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS04905
gene id: 37928:AC20117_RS04905
uniprot id: A0A1H1DLB8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

37928:AC20117 RS22925
gene id: 37928:AC20117_RS22925
uniprot id: A0A1H1HW99
names: Similarity
messages: Belongs to the asparaginase 1 family.

37928:AC20117 RS19040
gene id: 37928:AC20117_RS19040
uniprot id: A0A1H1GFM4
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

37928:AC20117 RS00515
gene id: 37928:AC20117_RS00515
uniprot id: A0A1H1FED9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

37928:AC20117 RS06275
gene id: 37928:AC20117_RS06275
uniprot id: A0A1H1D2E6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS03430
gene id: 37928:AC20117_RS03430
uniprot id: A0A1H1E9N3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

37928:AC20117 RS09515
gene id: 37928:AC20117_RS09515
uniprot id: A0A1H1BTN3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS03495
gene id: 37928:AC20117_RS03495
uniprot id: A0A1H1E736
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01390
gene id: 37928:AC20117_RS01390
uniprot id: A0A1H1F2L1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

37928:AC20117 RS21480
gene id: 37928:AC20117_RS21480
uniprot id: A0A1H1FNZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

37928:AC20117 RS00630
gene id: 37928:AC20117_RS00630
uniprot id: A0A1H1FC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

37928:AC20117 RS22700
gene id: 37928:AC20117_RS22700
uniprot id: A0A1H1HUT9
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

37928:AC20117 RS00645
gene id: 37928:AC20117_RS00645
uniprot id: A0A1H1FCQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

37928:AC20117 RS06985
gene id: 37928:AC20117_RS06985
uniprot id: A0A1H1CTP4
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

37928:AC20117 RS08665
gene id: 37928:AC20117_RS08665
uniprot id: A0A1H1C551
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

37928:AC20117 RS05445
gene id: 37928:AC20117_RS05445
uniprot id: A0A1H1DDW9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS19985
gene id: 37928:AC20117_RS19985
uniprot id: A0A1H1G5U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

37928:AC20117 RS16135
gene id: 37928:AC20117_RS16135
uniprot id: A0A1H0Z9V1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS04545
gene id: 37928:AC20117_RS04545
uniprot id: A0A1H1DSA9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

37928:AC20117 RS14590
gene id: 37928:AC20117_RS14590
uniprot id: A0A1H0ZS51
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

37928:AC20117 RS04895
gene id: 37928:AC20117_RS04895
uniprot id: A0A1H1DMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

37928:AC20117 RS08925
gene id: 37928:AC20117_RS08925
uniprot id: A0A1H1C172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

37928:AC20117 RS11715
gene id: 37928:AC20117_RS11715
uniprot id: A0A1H1AW79
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

37928:AC20117 RS18800
gene id: 37928:AC20117_RS18800
uniprot id: A0A1H1GIF5
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

37928:AC20117 RS22135
gene id: 37928:AC20117_RS22135
uniprot id: A0A1H1HY00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS17865
gene id: 37928:AC20117_RS17865
uniprot id: A0A1H1GSI3
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

37928:AC20117 RS01580
gene id: 37928:AC20117_RS01580
uniprot id: A0A1H1F006
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

37928:AC20117 RS17235
gene id: 37928:AC20117_RS17235
uniprot id: A0A1H1GZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

37928:AC20117 RS19010
gene id: 37928:AC20117_RS19010
uniprot id: A0A1H1GGA7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS05600
gene id: 37928:AC20117_RS05600
uniprot id: A0A1H1DBZ6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19515
gene id: 37928:AC20117_RS19515
uniprot id: A0A1H1GAT0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

37928:AC20117 RS01595
gene id: 37928:AC20117_RS01595
uniprot id: A0A1H1F0B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

37928:AC20117 RS06335
gene id: 37928:AC20117_RS06335
uniprot id: A0A1H1D1V0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

37928:AC20117 RS03350
gene id: 37928:AC20117_RS03350
uniprot id: A0A1H1E9I2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

37928:AC20117 RS13565
gene id: 37928:AC20117_RS13565
uniprot id: A0A1H1A4F1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18190
gene id: 37928:AC20117_RS18190
uniprot id: A0A1H1GPS8
names: Similarity
messages: Belongs to the DapA family.

37928:AC20117 RS21575
gene id: 37928:AC20117_RS21575
uniprot id: A0A1H1FNF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS17755
gene id: 37928:AC20117_RS17755
uniprot id: A0A1H1GTF6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

37928:AC20117 RS06190
gene id: 37928:AC20117_RS06190
uniprot id: A0A1H1D3W8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

37928:AC20117 RS16100
gene id: 37928:AC20117_RS16100
uniprot id: A0A1H0Z9L3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

37928:AC20117 RS06385
gene id: 37928:AC20117_RS06385
uniprot id: A0A1H1D1Q1
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

37928:AC20117 RS16855
gene id: 37928:AC20117_RS16855
uniprot id: A0A1H1H152
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

37928:AC20117 RS01400
gene id: 37928:AC20117_RS01400
uniprot id: A0A1H1F2Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

37928:AC20117 RS17165
gene id: 37928:AC20117_RS17165
uniprot id: A0A1H1GZP3
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

37928:AC20117 RS17565
gene id: 37928:AC20117_RS17565
uniprot id: A0A1H1GUY2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

37928:AC20117 RS17070
gene id: 37928:AC20117_RS17070
uniprot id: A0A1H1GZC5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

37928:AC20117 RS22595
gene id: 37928:AC20117_RS22595
uniprot id: A0A1H1I0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS11495
gene id: 37928:AC20117_RS11495
uniprot id: A0A1H1AZR9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

37928:AC20117 RS19995
gene id: 37928:AC20117_RS19995
uniprot id: A0A1H1G6F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

37928:AC20117 RS11195
gene id: 37928:AC20117_RS11195
uniprot id: A0A1H1B4A3
names: Similarity
messages: Belongs to the group II decarboxylase family.

37928:AC20117 RS12220
gene id: 37928:AC20117_RS12220
uniprot id: A0A1H1AN87
names: Similarity
messages: Belongs to the DapA family.

37928:AC20117 RS18165
gene id: 37928:AC20117_RS18165
uniprot id: A0A1H1GQ19
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS05395
gene id: 37928:AC20117_RS05395
uniprot id: A0A1H1DEE1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

37928:AC20117 RS20585
gene id: 37928:AC20117_RS20585
uniprot id: A0A1H1FZD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

37928:AC20117 RS01475
gene id: 37928:AC20117_RS01475
uniprot id: A0A1H1F1Q5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

37928:AC20117 RS16280
gene id: 37928:AC20117_RS16280
uniprot id: A0A1H1H772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS17240
gene id: 37928:AC20117_RS17240
uniprot id: A0A1H1GY35
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19190
gene id: 37928:AC20117_RS19190
uniprot id: A0A1H1GEB6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

37928:AC20117 RS03310
gene id: 37928:AC20117_RS03310
uniprot id: A0A1H1E9Z4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

37928:AC20117 RS01240
gene id: 37928:AC20117_RS01240
uniprot id: A0A1H1F4Z6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

37928:AC20117 RS04675
gene id: 37928:AC20117_RS04675
uniprot id: A0A1H1DPS5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

37928:AC20117 RS01075
gene id: 37928:AC20117_RS01075
uniprot id: A0A1H1F6Z8
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

37928:AC20117 RS10655
gene id: 37928:AC20117_RS10655
uniprot id: A0A1H1BC21
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

37928:AC20117 RS10835
gene id: 37928:AC20117_RS10835
uniprot id: A0A1H1B8X3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

37928:AC20117 RS09920
gene id: 37928:AC20117_RS09920
uniprot id: A0A1H1BMS1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

37928:AC20117 RS04445
gene id: 37928:AC20117_RS04445
uniprot id: A0A1H1DT54
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06455
gene id: 37928:AC20117_RS06455
uniprot id: A0A1H1D063
names: Similarity
messages: Belongs to the GcvT family.

37928:AC20117 RS07960
gene id: 37928:AC20117_RS07960
uniprot id: A0A1H1CEA8
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

37928:AC20117 RS13825
gene id: 37928:AC20117_RS13825
uniprot id: A0A1H1A147
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19965
gene id: 37928:AC20117_RS19965
uniprot id: A0A1H1G6R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

37928:AC20117 RS16155
gene id: 37928:AC20117_RS16155
uniprot id: A0A1H1H8F5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS06680
gene id: 37928:AC20117_RS06680
uniprot id: A0A1H1CXG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS16295
gene id: 37928:AC20117_RS16295
uniprot id: A0A1H1H620
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

37928:AC20117 RS11995
gene id: 37928:AC20117_RS11995
uniprot id: A0A1H1AS94
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

37928:AC20117 RS12145
gene id: 37928:AC20117_RS12145
uniprot id: A0A1H1APP4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS11595
gene id: 37928:AC20117_RS11595
uniprot id: A0A1H1AXX9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

37928:AC20117 RS13700
gene id: 37928:AC20117_RS13700
uniprot id: A0A1H1A2L9
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

37928:AC20117 RS14470
gene id: 37928:AC20117_RS14470
uniprot id: A0A1H0ZTI3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

37928:AC20117 RS07670
gene id: 37928:AC20117_RS07670
uniprot id: A0A1H1CIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

37928:AC20117 RS09600
gene id: 37928:AC20117_RS09600
uniprot id: A0A1H1BSK1
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

37928:AC20117 RS20460
gene id: 37928:AC20117_RS20460
uniprot id: A0A1H1G116
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

37928:AC20117 RS16690
gene id: 37928:AC20117_RS16690
uniprot id: A0A1H1H2J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

37928:AC20117 RS12230
gene id: 37928:AC20117_RS12230
uniprot id: A0A1H1ANC6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07855
gene id: 37928:AC20117_RS07855
uniprot id: A0A1H1CH90
names: Similarity
messages: Belongs to the Nth/MutY family.

37928:AC20117 RS09010
gene id: 37928:AC20117_RS09010
uniprot id: A0A1H1C075
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

37928:AC20117 RS13080
gene id: 37928:AC20117_RS13080
uniprot id: A0A1H1AB12
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS07215
gene id: 37928:AC20117_RS07215
uniprot id: A0A1H1CQB1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS07295
gene id: 37928:AC20117_RS07295
uniprot id: A0A1H1CNS8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

37928:AC20117 RS13330
gene id: 37928:AC20117_RS13330
uniprot id: A0A1H1A7N1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

37928:AC20117 RS19585
gene id: 37928:AC20117_RS19585
uniprot id: A0A1H1GA81
names: Similarity
messages: Belongs to the LacAB/RpiB family.

37928:AC20117 RS08885
gene id: 37928:AC20117_RS08885
uniprot id: A0A1H1C1S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

37928:AC20117 RS18790
gene id: 37928:AC20117_RS18790
uniprot id: A0A1H1GJ94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS13515
gene id: 37928:AC20117_RS13515
uniprot id: A0A1H1A501
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

37928:AC20117 RS01405
gene id: 37928:AC20117_RS01405
uniprot id: A0A1H1F410
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

37928:AC20117 RS04775
gene id: 37928:AC20117_RS04775
uniprot id: A0A1H1DNZ1
names: Similarity
messages: Belongs to the thioredoxin family.

37928:AC20117 RS01260
gene id: 37928:AC20117_RS01260
uniprot id: A0A1H1F4E3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS07630
gene id: 37928:AC20117_RS07630
uniprot id: A0A1H1CJ74
names: Similarity
messages: Belongs to the phosphohexose mutase family.

37928:AC20117 RS02275
gene id: 37928:AC20117_RS02275
uniprot id: A0A1H1EQ90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

37928:AC20117 RS14515
gene id: 37928:AC20117_RS14515
uniprot id: A0A1H0ZTE1
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

37928:AC20117 RS10270
gene id: 37928:AC20117_RS10270
uniprot id: A0A1H1BHL0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

37928:AC20117 RS11660
gene id: 37928:AC20117_RS11660
uniprot id: A0A1H1AX21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

37928:AC20117 RS16700
gene id: 37928:AC20117_RS16700
uniprot id: A0A1H1H2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

37928:AC20117 RS16915
gene id: 37928:AC20117_RS16915
uniprot id: A0A1H1H0T2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS20340
gene id: 37928:AC20117_RS20340
uniprot id: A0A1H1G2E1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

37928:AC20117 RS14180
gene id: 37928:AC20117_RS14180
uniprot id: A0A1H0ZX97
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

37928:AC20117 RS07865
gene id: 37928:AC20117_RS07865
uniprot id: A0A1H1CFT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

37928:AC20117 RS12695
gene id: 37928:AC20117_RS12695
uniprot id: A0A1H1AHX8
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS07745
gene id: 37928:AC20117_RS07745
uniprot id: A0A1H1CHH5
names: Similarity
messages: Belongs to the peptidase S13 family.

37928:AC20117 RS02750
gene id: 37928:AC20117_RS02750
uniprot id: A0A1H1EHX1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

37928:AC20117 RS18155
gene id: 37928:AC20117_RS18155
uniprot id: A0A1H1GQY1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

37928:AC20117 RS10635
gene id: 37928:AC20117_RS10635
uniprot id: A0A1H1BCC3
names: Function
names: Similarity
messages: Belongs to the bacterial two-domain DSD family.
messages: Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways.

37928:AC20117 RS05915
gene id: 37928:AC20117_RS05915
uniprot id: A0A1H1D7F2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS10865
gene id: 37928:AC20117_RS10865
uniprot id: A0A1H1B8F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

37928:AC20117 RS11665
gene id: 37928:AC20117_RS11665
uniprot id: A0A1H1AWT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

37928:AC20117 RS07555
gene id: 37928:AC20117_RS07555
uniprot id: A0A1H1CK92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

37928:AC20117 RS03665
gene id: 37928:AC20117_RS03665
uniprot id: A0A1H1E4D9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

37928:AC20117 RS18170
gene id: 37928:AC20117_RS18170
uniprot id: A0A1H1GPU3
names: Similarity
messages: Belongs to the GPI family.

37928:AC20117 RS01715
gene id: 37928:AC20117_RS01715
uniprot id: A0A1H1EZS9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

37928:AC20117 RS16590
gene id: 37928:AC20117_RS16590
uniprot id: A0A1H1H3G3
names: Similarity
messages: Belongs to the ribF family.

37928:AC20117 RS12075
gene id: 37928:AC20117_RS12075
uniprot id: A0A1H1AS16
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

37928:AC20117 RS08420
gene id: 37928:AC20117_RS08420
uniprot id: A0A1H1C9D6
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

37928:AC20117 RS05245
gene id: 37928:AC20117_RS05245
uniprot id: A0A1H1DGS5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

37928:AC20117 RS18295
gene id: 37928:AC20117_RS18295
uniprot id: A0A1H1GNK3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

37928:AC20117 RS09620
gene id: 37928:AC20117_RS09620
uniprot id: A0A1H1BSF5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS14740
gene id: 37928:AC20117_RS14740
uniprot id: A0A1H0ZQC7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

37928:AC20117 RS00995
gene id: 37928:AC20117_RS00995
uniprot id: A0A1H1F853
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

37928:AC20117 RS19565
gene id: 37928:AC20117_RS19565
uniprot id: A0A1H1GA99
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

37928:AC20117 RS00720
gene id: 37928:AC20117_RS00720
uniprot id: A0A1H1FB45
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

37928:AC20117 RS20280
gene id: 37928:AC20117_RS20280
uniprot id: A0A1H1G2T2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS20625
gene id: 37928:AC20117_RS20625
uniprot id: A0A1H1FYW9
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

37928:AC20117 RS05785
gene id: 37928:AC20117_RS05785
uniprot id: A0A1H1DB84
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS06050
gene id: 37928:AC20117_RS06050
uniprot id: A0A1H1D7L1
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13650
gene id: 37928:AC20117_RS13650
uniprot id: A0A1H1A372
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

37928:AC20117 RS12975
gene id: 37928:AC20117_RS12975
uniprot id: A0A1H1ACL1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS14290
gene id: 37928:AC20117_RS14290
uniprot id: A0A1H0ZVP1
names: Similarity
messages: Belongs to the peptidase M20A family.

37928:AC20117 RS19445
gene id: 37928:AC20117_RS19445
uniprot id: A0A1H1GBF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

37928:AC20117 RS08510
gene id: 37928:AC20117_RS08510
uniprot id: A0A1H1C6K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS22995
gene id: 37928:AC20117_RS22995
uniprot id: A0A1H1HWT7
names: Similarity
messages: Belongs to the CdaR family.

37928:AC20117 RS20060
gene id: 37928:AC20117_RS20060
uniprot id: A0A1H1G4Z3
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

37928:AC20117 RS09835
gene id: 37928:AC20117_RS09835
uniprot id: A0A1H1BP16
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS18580
gene id: 37928:AC20117_RS18580
uniprot id: A0A1H1GKK1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS08875
gene id: 37928:AC20117_RS08875
uniprot id: A0A1H1C244
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

37928:AC20117 RS21235
gene id: 37928:AC20117_RS21235
uniprot id: A0A1H1FRV0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09005
gene id: 37928:AC20117_RS09005
uniprot id: A0A1H1C083
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS21585
gene id: 37928:AC20117_RS21585
uniprot id: A0A1H1FMY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

37928:AC20117 RS11590
gene id: 37928:AC20117_RS11590
uniprot id: A0A1H1AY49
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

37928:AC20117 RS09375
gene id: 37928:AC20117_RS09375
uniprot id: A0A1H1BVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS14840
gene id: 37928:AC20117_RS14840
uniprot id: A0A1H0ZNK8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS02435
gene id: 37928:AC20117_RS02435
uniprot id: A0A1H1EMR1
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS23040
gene id: 37928:AC20117_RS23040
uniprot id: A0A1H1HWZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

37928:AC20117 RS08070
gene id: 37928:AC20117_RS08070
uniprot id: A0A1H1CCU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

37928:AC20117 RS07385
gene id: 37928:AC20117_RS07385
uniprot id: A0A1H1CMQ1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS14040
gene id: 37928:AC20117_RS14040
uniprot id: A0A1H0ZYT8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS19905
gene id: 37928:AC20117_RS19905
uniprot id: A0A1H1G7S6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

37928:AC20117 RS22580
gene id: 37928:AC20117_RS22580
uniprot id: A0A1H1I0H5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

37928:AC20117 RS20755
gene id: 37928:AC20117_RS20755
uniprot id: A0A1H1FYA8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06560
gene id: 37928:AC20117_RS06560
uniprot id: A0A1H1CZU3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS01365
gene id: 37928:AC20117_RS01365
uniprot id: A0A1H1F337
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS12895
gene id: 37928:AC20117_RS12895
uniprot id: A0A1H1ADS8
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

37928:AC20117 RS13190
gene id: 37928:AC20117_RS13190
uniprot id: A0A1H1A9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS10640
gene id: 37928:AC20117_RS10640
uniprot id: A0A1H1BBX9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS03740
gene id: 37928:AC20117_RS03740
uniprot id: A0A1H1E322
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS19555
gene id: 37928:AC20117_RS19555
uniprot id: A0A1H1GB57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

37928:AC20117 RS19195
gene id: 37928:AC20117_RS19195
uniprot id: A0A1H1GE21
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

37928:AC20117 RS06240
gene id: 37928:AC20117_RS06240
uniprot id: A0A1H1D362
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

37928:AC20117 RS02030
gene id: 37928:AC20117_RS02030
uniprot id: A0A1H1ETU7
names: Similarity
messages: Belongs to the catalase family.

37928:AC20117 RS13625
gene id: 37928:AC20117_RS13625
uniprot id: A0A1H1A3N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS08900
gene id: 37928:AC20117_RS08900
uniprot id: A0A1H1C1S0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

37928:AC20117 RS19770
gene id: 37928:AC20117_RS19770
uniprot id: A0A1H1G8W7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

37928:AC20117 RS17045
gene id: 37928:AC20117_RS17045
uniprot id: A0A1H1GZW3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS15510
gene id: 37928:AC20117_RS15510
uniprot id: A0A1H0ZGE0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07300
gene id: 37928:AC20117_RS07300
uniprot id: A0A1H1CQP6
names: Similarity
messages: Belongs to the thioredoxin family.

37928:AC20117 RS17040
gene id: 37928:AC20117_RS17040
uniprot id: A0A1H1GZL3
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS14575
gene id: 37928:AC20117_RS14575
uniprot id: A0A1H0ZS75
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

37928:AC20117 RS09935
gene id: 37928:AC20117_RS09935
uniprot id: A0A1H1BMI2
names: Similarity
messages: Belongs to the cytochrome P450 family.

37928:AC20117 RS00685
gene id: 37928:AC20117_RS00685
uniprot id: A0A1H1FC38
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

37928:AC20117 RS17430
gene id: 37928:AC20117_RS17430
uniprot id: A0A1H1GW51
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19955
gene id: 37928:AC20117_RS19955
uniprot id: A0A1H1G761
names: Similarity
messages: Belongs to the UPF0102 family.

37928:AC20117 RS15860
gene id: 37928:AC20117_RS15860
uniprot id: A0A1H0ZCA8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

37928:AC20117 RS08210
gene id: 37928:AC20117_RS08210
uniprot id: A0A1H1CAY1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

37928:AC20117 RS18115
gene id: 37928:AC20117_RS18115
uniprot id: A0A1H1GQD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

37928:AC20117 RS05980
gene id: 37928:AC20117_RS05980
uniprot id: A0A1H1D6F0
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

37928:AC20117 RS07510
gene id: 37928:AC20117_RS07510
uniprot id: A0A1H1CL72
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

37928:AC20117 RS08380
gene id: 37928:AC20117_RS08380
uniprot id: A0A1H1C9Y6
names: Subcellular Location Annotation
messages: Periplasm

37928:AC20117 RS05780
gene id: 37928:AC20117_RS05780
uniprot id: A0A1H1DAA8
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

37928:AC20117 RS06590
gene id: 37928:AC20117_RS06590
uniprot id: A0A1H1CZ53
names: Similarity
messages: Belongs to the YciI family.

37928:AC20117 RS07565
gene id: 37928:AC20117_RS07565
uniprot id: A0A1H1CKF1
names: Similarity
messages: Belongs to the XFP family.

37928:AC20117 RS20130
gene id: 37928:AC20117_RS20130
uniprot id: A0A1H1G4A3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

37928:AC20117 RS16830
gene id: 37928:AC20117_RS16830
uniprot id: A0A1H1H1Q8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09545
gene id: 37928:AC20117_RS09545
uniprot id: A0A1H1BT80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS09280
gene id: 37928:AC20117_RS09280
uniprot id: A0A1H1BWN9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00140
gene id: 37928:AC20117_RS00140
uniprot id: A0A1H1FIX5
names: Similarity
messages: Belongs to the GSP E family.

37928:AC20117 RS20555
gene id: 37928:AC20117_RS20555
uniprot id: A0A1H1FZV1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS14030
gene id: 37928:AC20117_RS14030
uniprot id: A0A1H0ZYT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

37928:AC20117 RS01865
gene id: 37928:AC20117_RS01865
uniprot id: A0A1H1EWG6
names: Similarity
messages: Belongs to the peptidase C56 family.

37928:AC20117 RS13690
gene id: 37928:AC20117_RS13690
uniprot id: A0A1H1A2X4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS23775
gene id: 37928:AC20117_RS23775
uniprot id: A0A1H1EPP3
names: Similarity
messages: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.

37928:AC20117 RS08790
gene id: 37928:AC20117_RS08790
uniprot id: A0A1H1C314
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

37928:AC20117 RS09725
gene id: 37928:AC20117_RS09725
uniprot id: A0A1H1BQN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

37928:AC20117 RS17840
gene id: 37928:AC20117_RS17840
uniprot id: A0A1H1GSQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

37928:AC20117 RS13430
gene id: 37928:AC20117_RS13430
uniprot id: A0A1H1A703
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

37928:AC20117 RS21255
gene id: 37928:AC20117_RS21255
uniprot id: A0A1H1FRN8
names: Similarity
messages: Belongs to the MQO family.

37928:AC20117 RS05350
gene id: 37928:AC20117_RS05350
uniprot id: A0A1H1DFX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

37928:AC20117 RS05665
gene id: 37928:AC20117_RS05665
uniprot id: A0A1H1DAR0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17260
gene id: 37928:AC20117_RS17260
uniprot id: A0A1H1GYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

37928:AC20117 RS04615
gene id: 37928:AC20117_RS04615
uniprot id: A0A1H1DQN5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09415
gene id: 37928:AC20117_RS09415
uniprot id: A0A1H1BVG7
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

37928:AC20117 RS04280
gene id: 37928:AC20117_RS04280
uniprot id: A0A1H1DX36
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

37928:AC20117 RS00045
gene id: 37928:AC20117_RS00045
uniprot id: A0A1H1FJQ7
names: Similarity
messages: Belongs to the DtxR/MntR family.

37928:AC20117 RS19950
gene id: 37928:AC20117_RS19950
uniprot id: A0A1H1G780
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

37928:AC20117 RS12100
gene id: 37928:AC20117_RS12100
uniprot id: A0A1H1AQ90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS09990
gene id: 37928:AC20117_RS09990
uniprot id: A0A1H1BM97
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

37928:AC20117 RS14460
gene id: 37928:AC20117_RS14460
uniprot id: A0A1H0ZTQ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

37928:AC20117 RS05425
gene id: 37928:AC20117_RS05425
uniprot id: A0A1H1DFY6
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS11010
gene id: 37928:AC20117_RS11010
uniprot id: A0A1H1B6H3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS14720
gene id: 37928:AC20117_RS14720
uniprot id: A0A1H0ZRJ9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01545
gene id: 37928:AC20117_RS01545
uniprot id: A0A1H1F0T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

37928:AC20117 RS21670
gene id: 37928:AC20117_RS21670
uniprot id: A0A1H1FLV1
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

37928:AC20117 RS10605
gene id: 37928:AC20117_RS10605
uniprot id: A0A1H1BCN5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS02465
gene id: 37928:AC20117_RS02465
uniprot id: A0A1H1EN04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

37928:AC20117 RS00500
gene id: 37928:AC20117_RS00500
uniprot id: A0A1H1FDW7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

37928:AC20117 RS12310
gene id: 37928:AC20117_RS12310
uniprot id: A0A1H1AM05
names: Similarity
messages: Belongs to the cytochrome P450 family.

37928:AC20117 RS00205
gene id: 37928:AC20117_RS00205
uniprot id: A0A1H1FI99
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

37928:AC20117 RS02530
gene id: 37928:AC20117_RS02530
uniprot id: A0A1H1ELW8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

37928:AC20117 RS10170
gene id: 37928:AC20117_RS10170
uniprot id: A0A1H1BIQ8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS01530
gene id: 37928:AC20117_RS01530
uniprot id: A0A1H1F102
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

37928:AC20117 RS17010
gene id: 37928:AC20117_RS17010
uniprot id: A0A1H1H043
names: Subcellular Location Annotation
messages: Nucleus

37928:AC20117 RS17310
gene id: 37928:AC20117_RS17310
uniprot id: A0A1H1GYI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

37928:AC20117 RS04295
gene id: 37928:AC20117_RS04295
uniprot id: A0A1H1DVU5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

37928:AC20117 RS19175
gene id: 37928:AC20117_RS19175
uniprot id: A0A1H1GE23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

37928:AC20117 RS17315
gene id: 37928:AC20117_RS17315
uniprot id: A0A1H1GXJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

37928:AC20117 RS14035
gene id: 37928:AC20117_RS14035
uniprot id: A0A1H0ZYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

37928:AC20117 RS17250
gene id: 37928:AC20117_RS17250
uniprot id: A0A1H1GY05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

37928:AC20117 RS09250
gene id: 37928:AC20117_RS09250
uniprot id: A0A1H1BX13
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS19150
gene id: 37928:AC20117_RS19150
uniprot id: A0A1H1GEG7
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

37928:AC20117 RS12950
gene id: 37928:AC20117_RS12950
uniprot id: A0A1H1AE92
names: Similarity
messages: Belongs to the TPP enzyme family.

37928:AC20117 RS14855
gene id: 37928:AC20117_RS14855
uniprot id: A0A1H0ZNX2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

37928:AC20117 RS17290
gene id: 37928:AC20117_RS17290
uniprot id: A0A1H1GXH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

37928:AC20117 RS14640
gene id: 37928:AC20117_RS14640
uniprot id: A0A1H0ZS48
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

37928:AC20117 RS07345
gene id: 37928:AC20117_RS07345
uniprot id: A0A1H1CN11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

37928:AC20117 RS07925
gene id: 37928:AC20117_RS07925
uniprot id: A0A1H1CEW1
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

37928:AC20117 RS06330
gene id: 37928:AC20117_RS06330
uniprot id: A0A1H1D2Q4
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07115
gene id: 37928:AC20117_RS07115
uniprot id: A0A1H1CTJ7
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS01490
gene id: 37928:AC20117_RS01490
uniprot id: A0A1H1F1H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

37928:AC20117 RS22115
gene id: 37928:AC20117_RS22115
uniprot id: A0A1H1HXW2
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

37928:AC20117 RS07760
gene id: 37928:AC20117_RS07760
uniprot id: A0A1H1CHD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

37928:AC20117 RS09170
gene id: 37928:AC20117_RS09170
uniprot id: A0A1H1BY71
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

37928:AC20117 RS21910
gene id: 37928:AC20117_RS21910
uniprot id: A0A1H1FIW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

37928:AC20117 RS08320
gene id: 37928:AC20117_RS08320
uniprot id: A0A1H1C9N1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

37928:AC20117 RS10765
gene id: 37928:AC20117_RS10765
uniprot id: A0A1H1BA68
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS10645
gene id: 37928:AC20117_RS10645
uniprot id: A0A1H1BBU5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16490
gene id: 37928:AC20117_RS16490
uniprot id: A0A1H1H4B5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS13195
gene id: 37928:AC20117_RS13195
uniprot id: A0A1H1AAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS19650
gene id: 37928:AC20117_RS19650
uniprot id: A0A1H1GAB8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

37928:AC20117 RS03615
gene id: 37928:AC20117_RS03615
uniprot id: A0A1H1E5C5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

37928:AC20117 RS07885
gene id: 37928:AC20117_RS07885
uniprot id: A0A1H1CFQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

37928:AC20117 RS01685
gene id: 37928:AC20117_RS01685
uniprot id: A0A1H1EZ78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

37928:AC20117 RS13920
gene id: 37928:AC20117_RS13920
uniprot id: A0A1H1A053
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

37928:AC20117 RS10395
gene id: 37928:AC20117_RS10395
uniprot id: A0A1H1BF92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

37928:AC20117 RS02545
gene id: 37928:AC20117_RS02545
uniprot id: A0A1H1ELJ7
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

37928:AC20117 RS07105
gene id: 37928:AC20117_RS07105
uniprot id: A0A1H1CSS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

37928:AC20117 RS20125
gene id: 37928:AC20117_RS20125
uniprot id: A0A1H1G436
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

37928:AC20117 RS16685
gene id: 37928:AC20117_RS16685
uniprot id: A0A1H1H3T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

37928:AC20117 RS18015
gene id: 37928:AC20117_RS18015
uniprot id: A0A1H1GRB9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

37928:AC20117 RS04370
gene id: 37928:AC20117_RS04370
uniprot id: A0A1H1DVS4
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

37928:AC20117 RS11825
gene id: 37928:AC20117_RS11825
uniprot id: A0A1H1AVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS04235
gene id: 37928:AC20117_RS04235
uniprot id: A0A1H1DXR1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS11050
gene id: 37928:AC20117_RS11050
uniprot id: A0A1H1B5V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS06675
gene id: 37928:AC20117_RS06675
uniprot id: A0A1H1CYI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS17020
gene id: 37928:AC20117_RS17020
uniprot id: A0A1H1H032
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

37928:AC20117 RS19350
gene id: 37928:AC20117_RS19350
uniprot id: A0A1H1GCF5
names: Similarity
messages: Belongs to the peptidase S33 family.

37928:AC20117 RS16670
gene id: 37928:AC20117_RS16670
uniprot id: A0A1H1H390
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

37928:AC20117 RS01440
gene id: 37928:AC20117_RS01440
uniprot id: A0A1H1F1Z8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

37928:AC20117 RS10875
gene id: 37928:AC20117_RS10875
uniprot id: A0A1H1B8B7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

37928:AC20117 RS16725
gene id: 37928:AC20117_RS16725
uniprot id: A0A1H1H3H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

37928:AC20117 RS10055
gene id: 37928:AC20117_RS10055
uniprot id: A0A1H1BKN3
names: Similarity
messages: Belongs to the FPG family.

37928:AC20117 RS17015
gene id: 37928:AC20117_RS17015
uniprot id: A0A1H1GZU6
names: Similarity
messages: Belongs to the citrate synthase family.

37928:AC20117 RS08650
gene id: 37928:AC20117_RS08650
uniprot id: A0A1H1C4Y9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

37928:AC20117 RS19425
gene id: 37928:AC20117_RS19425
uniprot id: A0A1H1GBH1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS16355
gene id: 37928:AC20117_RS16355
uniprot id: A0A1H1H5U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

37928:AC20117 RS10490
gene id: 37928:AC20117_RS10490
uniprot id: A0A1H1BEP6
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

37928:AC20117 RS07880
gene id: 37928:AC20117_RS07880
uniprot id: A0A1H1CFH2
names: Similarity
messages: Belongs to the PstS family.

37928:AC20117 RS01410
gene id: 37928:AC20117_RS01410
uniprot id: A0A1H1F2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

37928:AC20117 RS05105
gene id: 37928:AC20117_RS05105
uniprot id: A0A1H1DIM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

37928:AC20117 RS22675
gene id: 37928:AC20117_RS22675
uniprot id: A0A1H1HUQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS00375
gene id: 37928:AC20117_RS00375
uniprot id: A0A1H1FEY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS21320
gene id: 37928:AC20117_RS21320
uniprot id: A0A1H1FRU5
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

37928:AC20117 RS02430
gene id: 37928:AC20117_RS02430
uniprot id: A0A1H1ENA7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

37928:AC20117 RS18620
gene id: 37928:AC20117_RS18620
uniprot id: A0A1H1GKC8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

37928:AC20117 RS09645
gene id: 37928:AC20117_RS09645
uniprot id: A0A1H1BSF6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

37928:AC20117 RS21365
gene id: 37928:AC20117_RS21365
uniprot id: A0A1H1DPH4
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

37928:AC20117 RS11420
gene id: 37928:AC20117_RS11420
uniprot id: A0A1H1B1Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

37928:AC20117 RS01385
gene id: 37928:AC20117_RS01385
uniprot id: A0A1H1F2U6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

37928:AC20117 RS18830
gene id: 37928:AC20117_RS18830
uniprot id: A0A1H1GHR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

37928:AC20117 RS00265
gene id: 37928:AC20117_RS00265
uniprot id: A0A1H1FH31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

37928:AC20117 RS17800
gene id: 37928:AC20117_RS17800
uniprot id: A0A1H1GT18
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

37928:AC20117 RS11000
gene id: 37928:AC20117_RS11000
uniprot id: A0A1H1B6L3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS12055
gene id: 37928:AC20117_RS12055
uniprot id: A0A1H1ARF9
names: Similarity
messages: Belongs to the CdaR family.

37928:AC20117 RS20835
gene id: 37928:AC20117_RS20835
uniprot id: A0A1H1FWC4
names: Similarity
messages: Belongs to the peptidase A8 family.

37928:AC20117 RS16985
gene id: 37928:AC20117_RS16985
uniprot id: A0A1H1H028
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS19470
gene id: 37928:AC20117_RS19470
uniprot id: A0A1H1GAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

37928:AC20117 RS06180
gene id: 37928:AC20117_RS06180
uniprot id: A0A1H1D407
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

37928:AC20117 RS01585
gene id: 37928:AC20117_RS01585
uniprot id: A0A1H1F0G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

37928:AC20117 RS07140
gene id: 37928:AC20117_RS07140
uniprot id: A0A1H1CT80
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

37928:AC20117 RS03285
gene id: 37928:AC20117_RS03285
uniprot id: A0A1H1EA79
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

37928:AC20117 RS04990
gene id: 37928:AC20117_RS04990
uniprot id: A0A1H1DJZ7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

37928:AC20117 RS17220
gene id: 37928:AC20117_RS17220
uniprot id: A0A1H1GY83
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS07315
gene id: 37928:AC20117_RS07315
uniprot id: A0A1H1CPF4
names: Similarity
messages: Belongs to the ParB family.

37928:AC20117 RS18635
gene id: 37928:AC20117_RS18635
uniprot id: A0A1H1GKW3
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

37928:AC20117 RS02175
gene id: 37928:AC20117_RS02175
uniprot id: A0A1H1ES91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS06705
gene id: 37928:AC20117_RS06705
uniprot id: A0A1H1CX84
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS01480
gene id: 37928:AC20117_RS01480
uniprot id: A0A1H1F1Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

37928:AC20117 RS05530
gene id: 37928:AC20117_RS05530
uniprot id: A0A1H1DCU3
names: Similarity
messages: Belongs to the CsoR family.

37928:AC20117 RS17820
gene id: 37928:AC20117_RS17820
uniprot id: A0A1H1GT02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

37928:AC20117 RS09775
gene id: 37928:AC20117_RS09775
uniprot id: A0A1H1BQ14
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS13490
gene id: 37928:AC20117_RS13490
uniprot id: A0A1H1A5F9
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS04685
gene id: 37928:AC20117_RS04685
uniprot id: A0A1H1DPV9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

37928:AC20117 RS19050
gene id: 37928:AC20117_RS19050
uniprot id: A0A1H1GFU8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS01355
gene id: 37928:AC20117_RS01355
uniprot id: A0A1H1F317
names: Similarity
messages: Belongs to the GSP E family.

37928:AC20117 RS01805
gene id: 37928:AC20117_RS01805
uniprot id: A0A1H1EYN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

37928:AC20117 RS17835
gene id: 37928:AC20117_RS17835
uniprot id: A0A1H1GTP6
names: Similarity
messages: Belongs to the TrpC family.

37928:AC20117 RS21405
gene id: 37928:AC20117_RS21405
uniprot id: A0A1H1FPE0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS05680
gene id: 37928:AC20117_RS05680
uniprot id: A0A1H1DAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

37928:AC20117 RS10700
gene id: 37928:AC20117_RS10700
uniprot id: A0A1H1BBG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

37928:AC20117 RS17280
gene id: 37928:AC20117_RS17280
uniprot id: A0A1H1GYL1
names: Similarity
messages: Belongs to the YggT family.

37928:AC20117 RS01540
gene id: 37928:AC20117_RS01540
uniprot id: A0A1H1F143
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

37928:AC20117 RS10975
gene id: 37928:AC20117_RS10975
uniprot id: A0A1H1B722
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

37928:AC20117 RS19095
gene id: 37928:AC20117_RS19095
uniprot id: A0A1H1GF41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

37928:AC20117 RS03890
gene id: 37928:AC20117_RS03890
uniprot id: A0A1H1E1T1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

37928:AC20117 RS11385
gene id: 37928:AC20117_RS11385
uniprot id: A0A1H1B103
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

37928:AC20117 RS21300
gene id: 37928:AC20117_RS21300
uniprot id: A0A1H1FR17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

37928:AC20117 RS07620
gene id: 37928:AC20117_RS07620
uniprot id: A0A1H1CJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

37928:AC20117 RS10160
gene id: 37928:AC20117_RS10160
uniprot id: A0A1H1BIW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

37928:AC20117 RS16885
gene id: 37928:AC20117_RS16885
uniprot id: A0A1H1H192
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

37928:AC20117 RS21605
gene id: 37928:AC20117_RS21605
uniprot id: A0A1H1FN60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

37928:AC20117 RS05975
gene id: 37928:AC20117_RS05975
uniprot id: A0A1H1D6S6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

37928:AC20117 RS06425
gene id: 37928:AC20117_RS06425
uniprot id: A0A1H1D0P2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

37928:AC20117 RS17375
gene id: 37928:AC20117_RS17375
uniprot id: A0A1H1GXT0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

37928:AC20117 RS07370
gene id: 37928:AC20117_RS07370
uniprot id: A0A1H1CMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

37928:AC20117 RS00675
gene id: 37928:AC20117_RS00675
uniprot id: A0A1H1FBP4
names: Similarity
messages: Belongs to the LOG family.

37928:AC20117 RS18145
gene id: 37928:AC20117_RS18145
uniprot id: A0A1H1GQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

37928:AC20117 RS13950
gene id: 37928:AC20117_RS13950
uniprot id: A0A1H0ZZY9
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

37928:AC20117 RS15925
gene id: 37928:AC20117_RS15925
uniprot id: A0A1H0ZBJ2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS04020
gene id: 37928:AC20117_RS04020
uniprot id: A0A1H1DYY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS01485
gene id: 37928:AC20117_RS01485
uniprot id: A0A1H1F1K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

37928:AC20117 RS06245
gene id: 37928:AC20117_RS06245
uniprot id: A0A1H1D344
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

37928:AC20117 RS09840
gene id: 37928:AC20117_RS09840
uniprot id: A0A1H1BQP3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS05905
gene id: 37928:AC20117_RS05905
uniprot id: A0A1H1D8L2
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

37928:AC20117 RS19255
gene id: 37928:AC20117_RS19255
uniprot id: A0A1H1GD70
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS17465
gene id: 37928:AC20117_RS17465
uniprot id: A0A1H1GW06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

37928:AC20117 RS13505
gene id: 37928:AC20117_RS13505
uniprot id: A0A1H1A583
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS19635
gene id: 37928:AC20117_RS19635
uniprot id: A0A1H1G9N3
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS21475
gene id: 37928:AC20117_RS21475
uniprot id: A0A1H1FP25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

37928:AC20117 RS04120
gene id: 37928:AC20117_RS04120
uniprot id: A0A1H1DYB8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

37928:AC20117 RS11900
gene id: 37928:AC20117_RS11900
uniprot id: A0A1H1AT32
names: Function
messages: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.

37928:AC20117 RS16605
gene id: 37928:AC20117_RS16605
uniprot id: A0A1H1H3P9
names: Similarity
messages: Belongs to the peptidase M16 family.

37928:AC20117 RS20560
gene id: 37928:AC20117_RS20560
uniprot id: A0A1H1FZX7
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

37928:AC20117 RS13830
gene id: 37928:AC20117_RS13830
uniprot id: A0A1H1A2C5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

37928:AC20117 RS16990
gene id: 37928:AC20117_RS16990
uniprot id: A0A1H1H014
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

37928:AC20117 RS14835
gene id: 37928:AC20117_RS14835
uniprot id: A0A1H0ZP57
names: Similarity
messages: Belongs to the FGGY kinase family.

37928:AC20117 RS17770
gene id: 37928:AC20117_RS17770
uniprot id: A0A1H1GTA8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

37928:AC20117 RS17675
gene id: 37928:AC20117_RS17675
uniprot id: A0A1H1GU58
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

37928:AC20117 RS18305
gene id: 37928:AC20117_RS18305
uniprot id: A0A1H1GPD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS04550
gene id: 37928:AC20117_RS04550
uniprot id: A0A1H1DRK5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS01815
gene id: 37928:AC20117_RS01815
uniprot id: A0A1H1EWT9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

37928:AC20117 RS02485
gene id: 37928:AC20117_RS02485
uniprot id: A0A1H1EM61
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18645
gene id: 37928:AC20117_RS18645
uniprot id: A0A1H1GJX1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

37928:AC20117 RS03325
gene id: 37928:AC20117_RS03325
uniprot id: A0A1H1E9M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

37928:AC20117 RS18175
gene id: 37928:AC20117_RS18175
uniprot id: A0A1H1GQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

37928:AC20117 RS08020
gene id: 37928:AC20117_RS08020
uniprot id: A0A1H1CDQ9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

37928:AC20117 RS13380
gene id: 37928:AC20117_RS13380
uniprot id: A0A1H1A6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS14200
gene id: 37928:AC20117_RS14200
uniprot id: A0A1H0ZWV6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

37928:AC20117 RS00980
gene id: 37928:AC20117_RS00980
uniprot id: A0A1H1F7I8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

37928:AC20117 RS19015
gene id: 37928:AC20117_RS19015
uniprot id: A0A1H1GGU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

37928:AC20117 RS15865
gene id: 37928:AC20117_RS15865
uniprot id: A0A1H0ZDB3
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

37928:AC20117 RS01550
gene id: 37928:AC20117_RS01550
uniprot id: A0A1H1F0Q8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

37928:AC20117 RS04850
gene id: 37928:AC20117_RS04850
uniprot id: A0A1H1DMW0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS08570
gene id: 37928:AC20117_RS08570
uniprot id: A0A1H1C5U5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

37928:AC20117 RS21285
gene id: 37928:AC20117_RS21285
uniprot id: A0A1H1FR78
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS01925
gene id: 37928:AC20117_RS01925
uniprot id: A0A1H1EX06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

37928:AC20117 RS13410
gene id: 37928:AC20117_RS13410
uniprot id: A0A1H1A6C0
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

37928:AC20117 RS13170
gene id: 37928:AC20117_RS13170
uniprot id: A0A1H1A9T6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS05970
gene id: 37928:AC20117_RS05970
uniprot id: A0A1H1D6M2
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

37928:AC20117 RS00275
gene id: 37928:AC20117_RS00275
uniprot id: A0A1H1FG94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

37928:AC20117 RS18705
gene id: 37928:AC20117_RS18705
uniprot id: A0A1H1GK48
names: Similarity
messages: Belongs to the peptidase S9C family.

37928:AC20117 RS16815
gene id: 37928:AC20117_RS16815
uniprot id: A0A1H1H2Q9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

37928:AC20117 RS00505
gene id: 37928:AC20117_RS00505
uniprot id: A0A1H1FDW8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

37928:AC20117 RS01080
gene id: 37928:AC20117_RS01080
uniprot id: A0A1H1F6K2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

37928:AC20117 RS19465
gene id: 37928:AC20117_RS19465
uniprot id: A0A1H1GAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

37928:AC20117 RS01740
gene id: 37928:AC20117_RS01740
uniprot id: A0A1H1EXS2
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS07945
gene id: 37928:AC20117_RS07945
uniprot id: A0A1H1CEJ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS06910
gene id: 37928:AC20117_RS06910
uniprot id: A0A1H1CUJ5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

37928:AC20117 RS17295
gene id: 37928:AC20117_RS17295
uniprot id: A0A1H1GYM7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

37928:AC20117 RS06605
gene id: 37928:AC20117_RS06605
uniprot id: A0A1H1CYE8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS04755
gene id: 37928:AC20117_RS04755
uniprot id: A0A1H1HYS4
names: Similarity
messages: Belongs to the CsoR family.

37928:AC20117 RS20895
gene id: 37928:AC20117_RS20895
uniprot id: A0A1H1FWU3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18060
gene id: 37928:AC20117_RS18060
uniprot id: A0A1H1GQY6
names: Similarity
messages: Belongs to the peptidase S33 family.

37928:AC20117 RS07595
gene id: 37928:AC20117_RS07595
uniprot id: A0A1H1CJJ5
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

37928:AC20117 RS00060
gene id: 37928:AC20117_RS00060
uniprot id: A0A1H1FJJ9
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

37928:AC20117 RS07940
gene id: 37928:AC20117_RS07940
uniprot id: A0A1H1CEN2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS11090
gene id: 37928:AC20117_RS11090
uniprot id: A0A1H1B5B1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS12275
gene id: 37928:AC20117_RS12275
uniprot id: A0A1H1AMG9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

37928:AC20117 RS10390
gene id: 37928:AC20117_RS10390
uniprot id: A0A1H1BFH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

37928:AC20117 RS17200
gene id: 37928:AC20117_RS17200
uniprot id: A0A1H1GY87
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

37928:AC20117 RS10385
gene id: 37928:AC20117_RS10385
uniprot id: A0A1H1BFI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

37928:AC20117 RS18130
gene id: 37928:AC20117_RS18130
uniprot id: A0A1H1GQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

37928:AC20117 RS07430
gene id: 37928:AC20117_RS07430
uniprot id: A0A1H1CNL7
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

37928:AC20117 RS00990
gene id: 37928:AC20117_RS00990
uniprot id: A0A1H1F873
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

37928:AC20117 RS20580
gene id: 37928:AC20117_RS20580
uniprot id: A0A1H1FZJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

37928:AC20117 RS09300
gene id: 37928:AC20117_RS09300
uniprot id: A0A1H1BWK8
names: Similarity
messages: Belongs to the PheA/TfdB FAD monooxygenase family.

37928:AC20117 RS10290
gene id: 37928:AC20117_RS10290
uniprot id: A0A1H1BH72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

37928:AC20117 RS21425
gene id: 37928:AC20117_RS21425
uniprot id: A0A1H1FPD9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

37928:AC20117 RS02690
gene id: 37928:AC20117_RS02690
uniprot id: A0A1H1EJ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

37928:AC20117 RS14070
gene id: 37928:AC20117_RS14070
uniprot id: A0A1H0ZYW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

37928:AC20117 RS19245
gene id: 37928:AC20117_RS19245
uniprot id: A0A1H1GDR4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

37928:AC20117 RS04090
gene id: 37928:AC20117_RS04090
uniprot id: A0A1H1DYF2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

37928:AC20117 RS04605
gene id: 37928:AC20117_RS04605
uniprot id: A0A1H1DR00
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS09550
gene id: 37928:AC20117_RS09550
uniprot id: A0A1H1BT89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
messages: Membrane

37928:AC20117 RS12845
gene id: 37928:AC20117_RS12845
uniprot id: A0A1H1AEB0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

37928:AC20117 RS00145
gene id: 37928:AC20117_RS00145
uniprot id: A0A1H1FIR0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16755
gene id: 37928:AC20117_RS16755
uniprot id: A0A1H1H377
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

37928:AC20117 RS00400
gene id: 37928:AC20117_RS00400
uniprot id: A0A1H1FFE5
names: Similarity
messages: Belongs to the PspA/IM30 family.

37928:AC20117 RS01945
gene id: 37928:AC20117_RS01945
uniprot id: A0A1H1EVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS05325
gene id: 37928:AC20117_RS05325
uniprot id: A0A1H1DFM1
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

37928:AC20117 RS13720
gene id: 37928:AC20117_RS13720
uniprot id: A0A1H1A3K7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

37928:AC20117 RS17575
gene id: 37928:AC20117_RS17575
uniprot id: A0A1H1GUZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

37928:AC20117 RS09810
gene id: 37928:AC20117_RS09810
uniprot id: A0A1H1BPR7
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS10285
gene id: 37928:AC20117_RS10285
uniprot id: A0A1H1BHT4
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

37928:AC20117 RS18390
gene id: 37928:AC20117_RS18390
uniprot id: A0A1H1GMJ6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

37928:AC20117 RS03280
gene id: 37928:AC20117_RS03280
uniprot id: A0A1H1EAA7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS17420
gene id: 37928:AC20117_RS17420
uniprot id: A0A1H1GWB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

37928:AC20117 RS04210
gene id: 37928:AC20117_RS04210
uniprot id: A0A1H1DWH8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16225
gene id: 37928:AC20117_RS16225
uniprot id: A0A1H1H6R6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

37928:AC20117 RS09510
gene id: 37928:AC20117_RS09510
uniprot id: A0A1H1BTU6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

37928:AC20117 RS09765
gene id: 37928:AC20117_RS09765
uniprot id: A0A1H1BQ12
names: Similarity
messages: Belongs to the peptidase S24 family.

37928:AC20117 RS01255
gene id: 37928:AC20117_RS01255
uniprot id: A0A1H1F4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

37928:AC20117 RS20320
gene id: 37928:AC20117_RS20320
uniprot id: A0A1H1G254
names: Similarity
messages: Belongs to the ABC transporter superfamily.

37928:AC20117 RS10715
gene id: 37928:AC20117_RS10715
uniprot id: A0A1H1BB30
names: Similarity
messages: Belongs to the WXG100 family.

37928:AC20117 RS09000
gene id: 37928:AC20117_RS09000
uniprot id: A0A1H1C0H1
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

37928:AC20117 RS18870
gene id: 37928:AC20117_RS18870
uniprot id: A0A1H1GHJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS15125
gene id: 37928:AC20117_RS15125
uniprot id: A0A1H0ZKU3
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS14255
gene id: 37928:AC20117_RS14255
uniprot id: A0A1H0ZW86
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

37928:AC20117 RS05010
gene id: 37928:AC20117_RS05010
uniprot id: A0A1H1DJV3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS05865
gene id: 37928:AC20117_RS05865
uniprot id: A0A1H1D986
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

37928:AC20117 RS02315
gene id: 37928:AC20117_RS02315
uniprot id: A0A1H1EQ01
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

37928:AC20117 RS14000
gene id: 37928:AC20117_RS14000
uniprot id: A0A1H1A0A4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

37928:AC20117 RS04770
gene id: 37928:AC20117_RS04770
uniprot id: A0A1H1DNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS04720
gene id: 37928:AC20117_RS04720
uniprot id: A0A1H1DP71
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

37928:AC20117 RS08225
gene id: 37928:AC20117_RS08225
uniprot id: A0A1H1CB42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

37928:AC20117 RS17760
gene id: 37928:AC20117_RS17760
uniprot id: A0A1H1GTH1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

37928:AC20117 RS21825
gene id: 37928:AC20117_RS21825
uniprot id: A0A1H1FKA3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS05750
gene id: 37928:AC20117_RS05750
uniprot id: A0A1H1D9Y6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS11415
gene id: 37928:AC20117_RS11415
uniprot id: A0A1H1B0J9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

37928:AC20117 RS20945
gene id: 37928:AC20117_RS20945
uniprot id: A0A1H1FW99
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS10810
gene id: 37928:AC20117_RS10810
uniprot id: A0A1H1B9A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

37928:AC20117 RS14130
gene id: 37928:AC20117_RS14130
uniprot id: A0A1H0ZXT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS03235
gene id: 37928:AC20117_RS03235
uniprot id: A0A1H1EAW8
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

37928:AC20117 RS19260
gene id: 37928:AC20117_RS19260
uniprot id: A0A1H1GD83
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS22525
gene id: 37928:AC20117_RS22525
uniprot id: A0A1H1I068
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

37928:AC20117 RS18820
gene id: 37928:AC20117_RS18820
uniprot id: A0A1H1GI28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

37928:AC20117 RS09210
gene id: 37928:AC20117_RS09210
uniprot id: A0A1H1BXM8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS00800
gene id: 37928:AC20117_RS00800
uniprot id: A0A1H1FAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS01645
gene id: 37928:AC20117_RS01645
uniprot id: A0A1H1EZ40
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS09320
gene id: 37928:AC20117_RS09320
uniprot id: A0A1H1BWC4
names: Similarity
messages: Belongs to the cytochrome P450 family.

37928:AC20117 RS05955
gene id: 37928:AC20117_RS05955
uniprot id: A0A1H1D6U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

37928:AC20117 RS01555
gene id: 37928:AC20117_RS01555
uniprot id: A0A1H1F0D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

37928:AC20117 RS10330
gene id: 37928:AC20117_RS10330
uniprot id: A0A1H1BG81
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

37928:AC20117 RS17615
gene id: 37928:AC20117_RS17615
uniprot id: A0A1H1GVE6
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS18695
gene id: 37928:AC20117_RS18695
uniprot id: A0A1H1GK85
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS00555
gene id: 37928:AC20117_RS00555
uniprot id: A0A1H1FDM9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

37928:AC20117 RS20195
gene id: 37928:AC20117_RS20195
uniprot id: A0A1H1G3I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS22305
gene id: 37928:AC20117_RS22305
uniprot id: A0A1H1HYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS20000
gene id: 37928:AC20117_RS20000
uniprot id: A0A1H1G5L4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

37928:AC20117 RS15300
gene id: 37928:AC20117_RS15300
uniprot id: A0A1H0ZJH5
names: Similarity
messages: Belongs to the SurE nucleotidase family.

37928:AC20117 RS07325
gene id: 37928:AC20117_RS07325
uniprot id: A0A1H1CNB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

37928:AC20117 RS21775
gene id: 37928:AC20117_RS21775
uniprot id: A0A1H1FKQ7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS21810
gene id: 37928:AC20117_RS21810
uniprot id: A0A1H1FK63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

37928:AC20117 RS11405
gene id: 37928:AC20117_RS11405
uniprot id: A0A1H1B0N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

37928:AC20117 RS22550
gene id: 37928:AC20117_RS22550
uniprot id: A0A1H1I093
names: Similarity
messages: Belongs to the NAPRTase family.

37928:AC20117 RS21590
gene id: 37928:AC20117_RS21590
uniprot id: A0A1H1FMW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

37928:AC20117 RS04095
gene id: 37928:AC20117_RS04095
uniprot id: A0A1H1DXZ0
names: Similarity
messages: Belongs to the HMG-CoA lyase family.
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

37928:AC20117 RS05950
gene id: 37928:AC20117_RS05950
uniprot id: A0A1H1D6W3
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

37928:AC20117 RS16415
gene id: 37928:AC20117_RS16415
uniprot id: A0A1H1H5D9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

37928:AC20117 RS12770
gene id: 37928:AC20117_RS12770
uniprot id: A0A1H1AGS5
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS15960
gene id: 37928:AC20117_RS15960
uniprot id: A0A1H0ZB43
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS02245
gene id: 37928:AC20117_RS02245
uniprot id: A0A1H1EQQ3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

37928:AC20117 RS02595
gene id: 37928:AC20117_RS02595
uniprot id: A0A1H1EL27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

37928:AC20117 RS12305
gene id: 37928:AC20117_RS12305
uniprot id: A0A1H1AM30
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06255
gene id: 37928:AC20117_RS06255
uniprot id: A0A1H1D3H4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

37928:AC20117 RS10760
gene id: 37928:AC20117_RS10760
uniprot id: A0A1H1BBW5
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS16610
gene id: 37928:AC20117_RS16610
uniprot id: A0A1H1H3A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS09025
gene id: 37928:AC20117_RS09025
uniprot id: A0A1H1C1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS20515
gene id: 37928:AC20117_RS20515
uniprot id: A0A1H1G0C8
names: Similarity
messages: Belongs to the AHA1 family.

37928:AC20117 RS14775
gene id: 37928:AC20117_RS14775
uniprot id: A0A1H0ZQW7
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

37928:AC20117 RS12175
gene id: 37928:AC20117_RS12175
uniprot id: A0A1H1AP43
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS17850
gene id: 37928:AC20117_RS17850
uniprot id: A0A1H1GT49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

37928:AC20117 RS06355
gene id: 37928:AC20117_RS06355
uniprot id: A0A1H1D1A8
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

37928:AC20117 RS07845
gene id: 37928:AC20117_RS07845
uniprot id: A0A1H1CFZ5
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

37928:AC20117 RS23000
gene id: 37928:AC20117_RS23000
uniprot id: A0A1H1HXM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

37928:AC20117 RS03100
gene id: 37928:AC20117_RS03100
uniprot id: A0A1H1ED06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

37928:AC20117 RS21665
gene id: 37928:AC20117_RS21665
uniprot id: A0A1H1FLX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

37928:AC20117 RS17335
gene id: 37928:AC20117_RS17335
uniprot id: A0A1H1GX21
names: Similarity
messages: Belongs to the glutamine synthetase family.

37928:AC20117 RS03245
gene id: 37928:AC20117_RS03245
uniprot id: A0A1H1EB60
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS16825
gene id: 37928:AC20117_RS16825
uniprot id: A0A1H1H1U8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13120
gene id: 37928:AC20117_RS13120
uniprot id: A0A1H1AAR0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13135
gene id: 37928:AC20117_RS13135
uniprot id: A0A1H1AA91
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

37928:AC20117 RS03970
gene id: 37928:AC20117_RS03970
uniprot id: A0A1H1DZR0
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

37928:AC20117 RS17970
gene id: 37928:AC20117_RS17970
uniprot id: A0A1H1GSP8
names: Similarity
messages: Belongs to the glutamine synthetase family.

37928:AC20117 RS11625
gene id: 37928:AC20117_RS11625
uniprot id: A0A1H1AXL1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS01705
gene id: 37928:AC20117_RS01705
uniprot id: A0A1H1EYH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

37928:AC20117 RS00390
gene id: 37928:AC20117_RS00390
uniprot id: A0A1H1FFJ4
names: Similarity
messages: Belongs to the peptidase S1C family.

37928:AC20117 RS04435
gene id: 37928:AC20117_RS04435
uniprot id: A0A1H1DUY3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

37928:AC20117 RS13500
gene id: 37928:AC20117_RS13500
uniprot id: A0A1H1A642
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

37928:AC20117 RS14630
gene id: 37928:AC20117_RS14630
uniprot id: A0A1H0ZRM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

37928:AC20117 RS11015
gene id: 37928:AC20117_RS11015
uniprot id: A0A1H1B697
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

37928:AC20117 RS05820
gene id: 37928:AC20117_RS05820
uniprot id: A0A1H1D8U5
names: Similarity
messages: Belongs to the malate synthase family.

37928:AC20117 RS00595
gene id: 37928:AC20117_RS00595
uniprot id: A0A1H1FDI3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

37928:AC20117 RS03070
gene id: 37928:AC20117_RS03070
uniprot id: A0A1H1EDI0
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS06250
gene id: 37928:AC20117_RS06250
uniprot id: A0A1H1D307
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

37928:AC20117 RS04470
gene id: 37928:AC20117_RS04470
uniprot id: A0A1H1DSU8
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

37928:AC20117 RS17230
gene id: 37928:AC20117_RS17230
uniprot id: A0A1H1GY13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS20205
gene id: 37928:AC20117_RS20205
uniprot id: A0A1H1G3D9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

37928:AC20117 RS20215
gene id: 37928:AC20117_RS20215
uniprot id: A0A1H1G343
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

37928:AC20117 RS08645
gene id: 37928:AC20117_RS08645
uniprot id: A0A1H1C505
names: Cofactor
messages: Can also use Mn(2+) ion.

37928:AC20117 RS07775
gene id: 37928:AC20117_RS07775
uniprot id: A0A1H1CH79
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

37928:AC20117 RS03625
gene id: 37928:AC20117_RS03625
uniprot id: A0A1H1E5C1
names: Subcellular Location Annotation
messages: Cytoplasm

37928:AC20117 RS12280
gene id: 37928:AC20117_RS12280
uniprot id: A0A1H1ANZ2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

37928:AC20117 RS01665
gene id: 37928:AC20117_RS01665
uniprot id: A0A1H1EZE1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

37928:AC20117 RS11980
gene id: 37928:AC20117_RS11980
uniprot id: A0A1H1ASE9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

37928:AC20117 RS15250
gene id: 37928:AC20117_RS15250
uniprot id: A0A1H0ZK62
names: Similarity
messages: Belongs to the universal stress protein A family.

37928:AC20117 RS01415
gene id: 37928:AC20117_RS01415
uniprot id: A0A1H1F2I3
names: Similarity
messages: Belongs to the peptidase S58 family.

37928:AC20117 RS15330
gene id: 37928:AC20117_RS15330
uniprot id: A0A1H0ZID3
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

37928:AC20117 RS22160
gene id: 37928:AC20117_RS22160
uniprot id: A0A1H1HZ13
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

37928:AC20117 RS00610
gene id: 37928:AC20117_RS00610
uniprot id: A0A1H1FCQ5
names: Similarity
messages: Belongs to the peptidase M24B family.

37928:AC20117 RS16305
gene id: 37928:AC20117_RS16305
uniprot id: A0A1H1H670
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

37928:AC20117 RS14860
gene id: 37928:AC20117_RS14860
uniprot id: A0A1H0ZPD0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

37928:AC20117 RS18630
gene id: 37928:AC20117_RS18630
uniprot id: A0A1H1GKY2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

37928:AC20117 RS12480
gene id: 37928:AC20117_RS12480
uniprot id: A0A1H1AL79
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.

37928:AC20117 RS10770
gene id: 37928:AC20117_RS10770
uniprot id: A0A1H1BBR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS01745
gene id: 37928:AC20117_RS01745
uniprot id: A0A1H1EY13
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS13215
gene id: 37928:AC20117_RS13215
uniprot id: A0A1H1A8W8
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS15120
gene id: 37928:AC20117_RS15120
uniprot id: A0A1H0ZKW1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

37928:AC20117 RS19125
gene id: 37928:AC20117_RS19125
uniprot id: A0A1H1GFP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

37928:AC20117 RS01620
gene id: 37928:AC20117_RS01620
uniprot id: A0A1H1F017
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

37928:AC20117 RS06635
gene id: 37928:AC20117_RS06635
uniprot id: A0A1H1CXU8
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

37928:AC20117 RS23070
gene id: 37928:AC20117_RS23070
uniprot id: A0A1H1HX26
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

37928:AC20117 RS18940
gene id: 37928:AC20117_RS18940
uniprot id: A0A1H1GGR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

37928:AC20117 RS00825
gene id: 37928:AC20117_RS00825
uniprot id: A0A1H1FAB1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

37928:AC20117 RS11960
gene id: 37928:AC20117_RS11960
uniprot id: A0A1H1AS47
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS04805
gene id: 37928:AC20117_RS04805
uniprot id: A0A1H1DNA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

37928:AC20117 RS01525
gene id: 37928:AC20117_RS01525
uniprot id: A0A1H1F107
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

37928:AC20117 RS02700
gene id: 37928:AC20117_RS02700
uniprot id: A0A1H1EJD7
names: Subcellular Location Annotation
messages: Membrane

37928:AC20117 RS12315
gene id: 37928:AC20117_RS12315
uniprot id: A0A1H1ANG3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

37928:AC20117 RS06090
gene id: 37928:AC20117_RS06090
uniprot id: A0A1H1D5W5
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.