369723:STROP RS16135
gene id: 369723:STROP_RS16135
uniprot id: A4X9S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

369723:STROP RS14170
gene id: 369723:STROP_RS14170
uniprot id: A4X8R4
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18480
gene id: 369723:STROP_RS18480
uniprot id: A4XB09
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS06895
gene id: 369723:STROP_RS06895
uniprot id: A4X4N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

369723:STROP RS19750
gene id: 369723:STROP_RS19750
uniprot id: A4XBP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

369723:STROP RS17505
gene id: 369723:STROP_RS17505
uniprot id: A4XAG9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

369723:STROP RS19705
gene id: 369723:STROP_RS19705
uniprot id: A4XBP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

369723:STROP RS19645
gene id: 369723:STROP_RS19645
uniprot id: A4XBM8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

369723:STROP RS10730
gene id: 369723:STROP_RS10730
uniprot id: A4X6T3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS23005
gene id: 369723:STROP_RS23005
uniprot id: A4XDG9
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

369723:STROP RS20590
gene id: 369723:STROP_RS20590
uniprot id: A4XC59
names: Similarity
messages: Belongs to the peptidase C40 family.

369723:STROP RS01310
gene id: 369723:STROP_RS01310
uniprot id: A4X1J2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01645
gene id: 369723:STROP_RS01645
uniprot id: A4X1R1
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

369723:STROP RS14400
gene id: 369723:STROP_RS14400
uniprot id: A4X8W0
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-69 and Arg-72) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

369723:STROP RS16365
gene id: 369723:STROP_RS16365
uniprot id: A4X9W1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

369723:STROP RS16520
gene id: 369723:STROP_RS16520
uniprot id: A4X9Z2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

369723:STROP RS13650
gene id: 369723:STROP_RS13650
uniprot id: A4X8F9
names: Similarity
messages: Belongs to the YciI family.

369723:STROP RS19665
gene id: 369723:STROP_RS19665
uniprot id: A4XBN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

369723:STROP RS15885
gene id: 369723:STROP_RS15885
uniprot id: A4X9N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

369723:STROP RS07900
gene id: 369723:STROP_RS07900
uniprot id: A4X586
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS12850
gene id: 369723:STROP_RS12850
uniprot id: A4X7Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

369723:STROP RS20980
gene id: 369723:STROP_RS20980
uniprot id: A4XCD0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

369723:STROP RS19075
gene id: 369723:STROP_RS19075
uniprot id: A4XBC5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

369723:STROP RS09740
gene id: 369723:STROP_RS09740
uniprot id: A4X691
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

369723:STROP RS04060
gene id: 369723:STROP_RS04060
uniprot id: A4X328
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

369723:STROP RS15115
gene id: 369723:STROP_RS15115
uniprot id: A4X994
names: Similarity
messages: Belongs to the band 7/mec-2 family.

369723:STROP RS15790
gene id: 369723:STROP_RS15790
uniprot id: A4X9L2
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

369723:STROP RS06210
gene id: 369723:STROP_RS06210
uniprot id: A4X4A3
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

369723:STROP RS16500
gene id: 369723:STROP_RS16500
uniprot id: A4X9Y8
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

369723:STROP RS01140
gene id: 369723:STROP_RS01140
uniprot id: A4X1F8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS00740
gene id: 369723:STROP_RS00740
uniprot id: A4X183
names: Similarity
messages: Belongs to the UPF0145 family.

369723:STROP RS08425
gene id: 369723:STROP_RS08425
uniprot id: A4X5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS15990
gene id: 369723:STROP_RS15990
uniprot id: A4X9Q2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

369723:STROP RS10285
gene id: 369723:STROP_RS10285
uniprot id: A4X6J3
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

369723:STROP RS16740
gene id: 369723:STROP_RS16740
uniprot id: A4XA34
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS18055
gene id: 369723:STROP_RS18055
uniprot id: A4XAS4
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS10375
gene id: 369723:STROP_RS10375
uniprot id: A4X6L1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

369723:STROP RS20455
gene id: 369723:STROP_RS20455
uniprot id: A4XC32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS03685
gene id: 369723:STROP_RS03685
uniprot id: A4X2V7
names: Similarity
messages: Belongs to the thioredoxin family.

369723:STROP RS18560
gene id: 369723:STROP_RS18560
uniprot id: A4XB25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

369723:STROP RS17665
gene id: 369723:STROP_RS17665
uniprot id: A4XAJ6
names: Similarity
messages: Belongs to the LacAB/RpiB family.

369723:STROP RS08615
gene id: 369723:STROP_RS08615
uniprot id: A4X5M2
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

369723:STROP RS12610
gene id: 369723:STROP_RS12610
uniprot id: A4X7V1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterotetramer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits of ACCase subunit beta/alpha.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity).
messages: Cytoplasm
messages: In the C-terminal section; belongs to the AccA family.
messages: In the N-terminal section; belongs to the AccD/PCCB family.

369723:STROP RS07100
gene id: 369723:STROP_RS07100
uniprot id: A4X4T0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS15475
gene id: 369723:STROP_RS15475
uniprot id: A4X9G1
names: Similarity
messages: Belongs to the GPI family.

369723:STROP RS14255
gene id: 369723:STROP_RS14255
uniprot id: A4X8T1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS08950
gene id: 369723:STROP_RS08950
uniprot id: A4X5T8
names: Subcellular Location Annotation
messages: Cytoplasm

369723:STROP RS22895
gene id: 369723:STROP_RS22895
uniprot id: A4XDM2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

369723:STROP RS15950
gene id: 369723:STROP_RS15950
uniprot id: A4X9P4
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS07225
gene id: 369723:STROP_RS07225
uniprot id: A4X4V5
names: Similarity
messages: Belongs to the EccD/Snm4 family.

369723:STROP RS00560
gene id: 369723:STROP_RS00560
uniprot id: A4X148
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

369723:STROP RS04455
gene id: 369723:STROP_RS04455
uniprot id: A4X3A6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

369723:STROP RS19790
gene id: 369723:STROP_RS19790
uniprot id: A4XBQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

369723:STROP RS08970
gene id: 369723:STROP_RS08970
uniprot id: A4X5U2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

369723:STROP RS06140
gene id: 369723:STROP_RS06140
uniprot id: A4X489
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

369723:STROP RS19925
gene id: 369723:STROP_RS19925
uniprot id: A4XBT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

369723:STROP RS19810
gene id: 369723:STROP_RS19810
uniprot id: A4XBR1
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

369723:STROP RS06695
gene id: 369723:STROP_RS06695
uniprot id: A4X4J7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

369723:STROP RS08500
gene id: 369723:STROP_RS08500
uniprot id: A4X5J9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS21770
gene id: 369723:STROP_RS21770
uniprot id: A4XCT7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS06550
gene id: 369723:STROP_RS06550
uniprot id: A4X4G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS01985
gene id: 369723:STROP_RS01985
uniprot id: A4X1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

369723:STROP RS22640
gene id: 369723:STROP_RS22640
uniprot id: A4XDA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

369723:STROP RS12700
gene id: 369723:STROP_RS12700
uniprot id: A4X7W8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS09145
gene id: 369723:STROP_RS09145
uniprot id: A4X5X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS09450
gene id: 369723:STROP_RS09450
uniprot id: A4X638
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

369723:STROP RS00630
gene id: 369723:STROP_RS00630
uniprot id: A4X162
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

369723:STROP RS19835
gene id: 369723:STROP_RS19835
uniprot id: A4XBR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

369723:STROP RS20925
gene id: 369723:STROP_RS20925
uniprot id: A4XCC0
names: Similarity
messages: Belongs to the NDK family.

369723:STROP RS05220
gene id: 369723:STROP_RS05220
uniprot id: A4X3Q5
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

369723:STROP RS04105
gene id: 369723:STROP_RS04105
uniprot id: A4X337
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS07710
gene id: 369723:STROP_RS07710
uniprot id: A4X549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

369723:STROP RS14265
gene id: 369723:STROP_RS14265
uniprot id: A4X8T3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS17990
gene id: 369723:STROP_RS17990
uniprot id: A4XAR0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

369723:STROP RS19010
gene id: 369723:STROP_RS19010
uniprot id: A4XBB3
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

369723:STROP RS15220
gene id: 369723:STROP_RS15220
uniprot id: A4X9B6
names: Similarity
messages: Belongs to the peptidase S8 family.

369723:STROP RS07375
gene id: 369723:STROP_RS07375
uniprot id: A4X4Y3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS10600
gene id: 369723:STROP_RS10600
uniprot id: A4X6Q7
names: Similarity
messages: Belongs to the DEAD box helicase family.

369723:STROP RS00230
gene id: 369723:STROP_RS00230
uniprot id: A4X0Y0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS13055
gene id: 369723:STROP_RS13055
uniprot id: A4X838
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

369723:STROP RS19640
gene id: 369723:STROP_RS19640
uniprot id: A4XBM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

369723:STROP RS18720
gene id: 369723:STROP_RS18720
uniprot id: A4XB58
names: Similarity
messages: Belongs to the SAICAR synthetase family.

369723:STROP RS20425
gene id: 369723:STROP_RS20425
uniprot id: A4XC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

369723:STROP RS10320
gene id: 369723:STROP_RS10320
uniprot id: A4X6K1
names: Similarity
messages: Belongs to the AHA1 family.

369723:STROP RS22500
gene id: 369723:STROP_RS22500
uniprot id: A4XD77
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18685
gene id: 369723:STROP_RS18685
uniprot id: A4XB51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

369723:STROP RS07155
gene id: 369723:STROP_RS07155
uniprot id: A4X4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

369723:STROP RS17865
gene id: 369723:STROP_RS17865
uniprot id: A4XAN6
names: Caution
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS20665
gene id: 369723:STROP_RS20665
uniprot id: A4XC74
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

369723:STROP RS15920
gene id: 369723:STROP_RS15920
uniprot id: A4X9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS02380
gene id: 369723:STROP_RS02380
uniprot id: A4X256
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS12495
gene id: 369723:STROP_RS12495
uniprot id: A4X7S9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12830
gene id: 369723:STROP_RS12830
uniprot id: A4X7Z4
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

369723:STROP RS14345
gene id: 369723:STROP_RS14345
uniprot id: A4X8V0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

369723:STROP RS18045
gene id: 369723:STROP_RS18045
uniprot id: A4XAS2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS05080
gene id: 369723:STROP_RS05080
uniprot id: A4X3M8
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

369723:STROP RS20755
gene id: 369723:STROP_RS20755
uniprot id: A4XC91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

369723:STROP RS06680
gene id: 369723:STROP_RS06680
uniprot id: A4X4J4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS22340
gene id: 369723:STROP_RS22340
uniprot id: A4XD48
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS08810
gene id: 369723:STROP_RS08810
uniprot id: A4X5R0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS22845
gene id: 369723:STROP_RS22845
uniprot id: A4XDE7
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

369723:STROP RS02485
gene id: 369723:STROP_RS02485
uniprot id: A4X277
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

369723:STROP RS11995
gene id: 369723:STROP_RS11995
uniprot id: A4X7I3
names: Similarity
messages: Belongs to the UPF0749 family.

369723:STROP RS19175
gene id: 369723:STROP_RS19175
uniprot id: A4XBE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

369723:STROP RS02195
gene id: 369723:STROP_RS02195
uniprot id: A4X219
names: Similarity
messages: Belongs to the CDP-glycerol glycerophosphotransferase family.

369723:STROP RS22730
gene id: 369723:STROP_RS22730
uniprot id: A4XDC3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS21535
gene id: 369723:STROP_RS21535
uniprot id: A4XCP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

369723:STROP RS12695
gene id: 369723:STROP_RS12695
uniprot id: A4X7W7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

369723:STROP RS08650
gene id: 369723:STROP_RS08650
uniprot id: A4X5N0
names: Similarity
messages: Belongs to the amidinotransferase family.

369723:STROP RS07150
gene id: 369723:STROP_RS07150
uniprot id: A4X4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

369723:STROP RS00880
gene id: 369723:STROP_RS00880
uniprot id: A4X1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

369723:STROP RS05995
gene id: 369723:STROP_RS05995
uniprot id: A4X461
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

369723:STROP RS14140
gene id: 369723:STROP_RS14140
uniprot id: A4X8Q8
names: Similarity
messages: Belongs to the thioesterase family.

369723:STROP RS07245
gene id: 369723:STROP_RS07245
uniprot id: A4X4V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS09025
gene id: 369723:STROP_RS09025
uniprot id: A4X5V3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

369723:STROP RS21630
gene id: 369723:STROP_RS21630
uniprot id: A4XCR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS21585
gene id: 369723:STROP_RS21585
uniprot id: A4XCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).
messages: Cytoplasm

369723:STROP RS12865
gene id: 369723:STROP_RS12865
uniprot id: A4X801
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

369723:STROP RS01170
gene id: 369723:STROP_RS01170
uniprot id: A4X1G4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

369723:STROP RS07835
gene id: 369723:STROP_RS07835
uniprot id: A4X574
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS11690
gene id: 369723:STROP_RS11690
uniprot id: A4X7C3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12435
gene id: 369723:STROP_RS12435
uniprot id: A4X7R7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

369723:STROP RS09520
gene id: 369723:STROP_RS09520
uniprot id: A4X652
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

369723:STROP RS15420
gene id: 369723:STROP_RS15420
uniprot id: A4X9F0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

369723:STROP RS07280
gene id: 369723:STROP_RS07280
uniprot id: A4X4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

369723:STROP RS07895
gene id: 369723:STROP_RS07895
uniprot id: A4X585
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

369723:STROP RS17445
gene id: 369723:STROP_RS17445
uniprot id: A4XAF7
names: Similarity
messages: Belongs to the peptidase M1 family.

369723:STROP RS21730
gene id: 369723:STROP_RS21730
uniprot id: A4XCS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

369723:STROP RS09380
gene id: 369723:STROP_RS09380
uniprot id: A4X624
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

369723:STROP RS03545
gene id: 369723:STROP_RS03545
uniprot id: A4X2S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

369723:STROP RS20060
gene id: 369723:STROP_RS20060
uniprot id: A4XBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS11635
gene id: 369723:STROP_RS11635
uniprot id: A4X7B2
names: Similarity
messages: Belongs to the YciI family.

369723:STROP RS05815
gene id: 369723:STROP_RS05815
uniprot id: A4X422
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

369723:STROP RS15830
gene id: 369723:STROP_RS15830
uniprot id: A4X9M0
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

369723:STROP RS18995
gene id: 369723:STROP_RS18995
uniprot id: A4XBB0
names: Similarity
messages: Belongs to the peptidase S45 family.

369723:STROP RS19805
gene id: 369723:STROP_RS19805
uniprot id: A4XBR0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

369723:STROP RS04585
gene id: 369723:STROP_RS04585
uniprot id: A4X3D2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

369723:STROP RS08405
gene id: 369723:STROP_RS08405
uniprot id: A4X5I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

369723:STROP RS21140
gene id: 369723:STROP_RS21140
uniprot id: A4XCG4
names: Similarity
messages: Belongs to the peptidase C56 family.

369723:STROP RS09130
gene id: 369723:STROP_RS09130
uniprot id: A4X5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

369723:STROP RS08515
gene id: 369723:STROP_RS08515
uniprot id: A4X5K2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

369723:STROP RS14930
gene id: 369723:STROP_RS14930
uniprot id: A4X961
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

369723:STROP RS04465
gene id: 369723:STROP_RS04465
uniprot id: A4X3A8
names: Similarity
messages: Belongs to the peptidase S8 family.

369723:STROP RS19785
gene id: 369723:STROP_RS19785
uniprot id: A4XBQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

369723:STROP RS12690
gene id: 369723:STROP_RS12690
uniprot id: A4X7W6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS16125
gene id: 369723:STROP_RS16125
uniprot id: A4X9S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

369723:STROP RS12480
gene id: 369723:STROP_RS12480
uniprot id: A4X7S6
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS14000
gene id: 369723:STROP_RS14000
uniprot id: A4X8N0
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

369723:STROP RS19440
gene id: 369723:STROP_RS19440
uniprot id: A4XBI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS01365
gene id: 369723:STROP_RS01365
uniprot id: A4X1K3
names: Subcellular Location Annotation
messages: Cytoplasm

369723:STROP RS10505
gene id: 369723:STROP_RS10505
uniprot id: A4X6N8
names: Similarity
messages: Belongs to the CsoR family.

369723:STROP RS01750
gene id: 369723:STROP_RS01750
uniprot id: A4X1T3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

369723:STROP RS12045
gene id: 369723:STROP_RS12045
uniprot id: A4X7J0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS15480
gene id: 369723:STROP_RS15480
uniprot id: A4X9G2
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS05525
gene id: 369723:STROP_RS05525
uniprot id: A4X3W6
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18320
gene id: 369723:STROP_RS18320
uniprot id: A4XAX6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

369723:STROP RS17565
gene id: 369723:STROP_RS17565
uniprot id: A4XAH8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

369723:STROP RS19225
gene id: 369723:STROP_RS19225
uniprot id: A4XBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS03060
gene id: 369723:STROP_RS03060
uniprot id: A4X2I3
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS01340
gene id: 369723:STROP_RS01340
uniprot id: A4X1J8
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

369723:STROP RS09410
gene id: 369723:STROP_RS09410
uniprot id: A4X630
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

369723:STROP RS03280
gene id: 369723:STROP_RS03280
uniprot id: A4X2M5
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

369723:STROP RS07265
gene id: 369723:STROP_RS07265
uniprot id: A4X4W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS17050
gene id: 369723:STROP_RS17050
uniprot id: A4XA86
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

369723:STROP RS18275
gene id: 369723:STROP_RS18275
uniprot id: A4XAW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

369723:STROP RS01475
gene id: 369723:STROP_RS01475
uniprot id: A4X1M5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS16600
gene id: 369723:STROP_RS16600
uniprot id: A4XA07
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

369723:STROP RS14060
gene id: 369723:STROP_RS14060
uniprot id: A4X8P2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS01100
gene id: 369723:STROP_RS01100
uniprot id: A4X1F0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

369723:STROP RS22445
gene id: 369723:STROP_RS22445
uniprot id: A4XD66
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS02185
gene id: 369723:STROP_RS02185
uniprot id: A4X217
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS09715
gene id: 369723:STROP_RS09715
uniprot id: A4X686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

369723:STROP RS24335
gene id: 369723:STROP_RS24335
uniprot id: A4XCD2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

369723:STROP RS20440
gene id: 369723:STROP_RS20440
uniprot id: A4XC29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS15055
gene id: 369723:STROP_RS15055
uniprot id: A4X982
names: Function
names: Similarity
messages: Belongs to the MurL family.
messages: Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.

369723:STROP RS12720
gene id: 369723:STROP_RS12720
uniprot id: A4X7X2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

369723:STROP RS04880
gene id: 369723:STROP_RS04880
uniprot id: A4X3I9
names: Similarity
messages: Belongs to the PGI/PMI family.

369723:STROP RS03515
gene id: 369723:STROP_RS03515
uniprot id: A4X2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

369723:STROP RS19615
gene id: 369723:STROP_RS19615
uniprot id: A4XBM2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

369723:STROP RS04130
gene id: 369723:STROP_RS04130
uniprot id: A4X342
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS07855
gene id: 369723:STROP_RS07855
uniprot id: A4X578
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS16495
gene id: 369723:STROP_RS16495
uniprot id: A4X9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

369723:STROP RS03575
gene id: 369723:STROP_RS03575
uniprot id: A4X2T4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS04745
gene id: 369723:STROP_RS04745
uniprot id: A4X3G3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

369723:STROP RS08445
gene id: 369723:STROP_RS08445
uniprot id: A4X5I8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS21305
gene id: 369723:STROP_RS21305
uniprot id: A4XCJ5
names: Similarity
messages: Belongs to the peptidase S8 family.

369723:STROP RS08270
gene id: 369723:STROP_RS08270
uniprot id: A4X5F5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS06790
gene id: 369723:STROP_RS06790
uniprot id: A4X4L7
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS05820
gene id: 369723:STROP_RS05820
uniprot id: A4X423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

369723:STROP RS15550
gene id: 369723:STROP_RS15550
uniprot id: A4X9G7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

369723:STROP RS13280
gene id: 369723:STROP_RS13280
uniprot id: A4X884
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS14670
gene id: 369723:STROP_RS14670
uniprot id: A4X915
names: Similarity
messages: Belongs to the UPF0246 family.

369723:STROP RS13125
gene id: 369723:STROP_RS13125
uniprot id: A4X852
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS04555
gene id: 369723:STROP_RS04555
uniprot id: A4X3C6
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

369723:STROP RS05435
gene id: 369723:STROP_RS05435
uniprot id: A4X3U8
names: Similarity
messages: Belongs to the CFA/CMAS family.

369723:STROP RS16175
gene id: 369723:STROP_RS16175
uniprot id: A4X9T3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS04445
gene id: 369723:STROP_RS04445
uniprot id: A4X3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

369723:STROP RS01110
gene id: 369723:STROP_RS01110
uniprot id: A4X1F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS12130
gene id: 369723:STROP_RS12130
uniprot id: A4X7K7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

369723:STROP RS07300
gene id: 369723:STROP_RS07300
uniprot id: A4X4W9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

369723:STROP RS15580
gene id: 369723:STROP_RS15580
uniprot id: A4X9H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

369723:STROP RS13645
gene id: 369723:STROP_RS13645
uniprot id: A4X8F8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS04295
gene id: 369723:STROP_RS04295
uniprot id: A4X375
names: Function
names: Similarity
messages: Belongs to the IMPDH/GMPR family. GuaB1 subfamily.
messages: Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.

369723:STROP RS23180
gene id: 369723:STROP_RS23180
uniprot id: A4XDK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

369723:STROP RS01405
gene id: 369723:STROP_RS01405
uniprot id: A4X1L0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS21270
gene id: 369723:STROP_RS21270
uniprot id: A4XCI9
names: Similarity
messages: Belongs to the YciI family.

369723:STROP RS19600
gene id: 369723:STROP_RS19600
uniprot id: A4XBL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

369723:STROP RS09360
gene id: 369723:STROP_RS09360
uniprot id: A4X620
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS17005
gene id: 369723:STROP_RS17005
uniprot id: A4XA78
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

369723:STROP RS19710
gene id: 369723:STROP_RS19710
uniprot id: A4XBP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

369723:STROP RS16270
gene id: 369723:STROP_RS16270
uniprot id: A4X9V1
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

369723:STROP RS06985
gene id: 369723:STROP_RS06985
uniprot id: A4X4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

369723:STROP RS19545
gene id: 369723:STROP_RS19545
uniprot id: A4XBK8
names: Function
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

369723:STROP RS06795
gene id: 369723:STROP_RS06795
uniprot id: A4X4L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

369723:STROP RS16505
gene id: 369723:STROP_RS16505
uniprot id: A4X9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS02140
gene id: 369723:STROP_RS02140
uniprot id: A4X208
names: Similarity
messages: Belongs to the citrate synthase family.

369723:STROP RS07160
gene id: 369723:STROP_RS07160
uniprot id: A4X4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

369723:STROP RS09190
gene id: 369723:STROP_RS09190
uniprot id: A4X5Y5
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS09100
gene id: 369723:STROP_RS09100
uniprot id: A4X5W8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS02020
gene id: 369723:STROP_RS02020
uniprot id: A4X1Y6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS16000
gene id: 369723:STROP_RS16000
uniprot id: A4X9Q5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

369723:STROP RS18640
gene id: 369723:STROP_RS18640
uniprot id: A4XB41
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19700
gene id: 369723:STROP_RS19700
uniprot id: A4XBN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

369723:STROP RS03910
gene id: 369723:STROP_RS03910
uniprot id: A4X2Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

369723:STROP RS03900
gene id: 369723:STROP_RS03900
uniprot id: A4X2Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS19540
gene id: 369723:STROP_RS19540
uniprot id: A4XBK7
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

369723:STROP RS23120
gene id: 369723:STROP_RS23120
uniprot id: A4XDJ2
names: Similarity
messages: Belongs to the thioredoxin family.

369723:STROP RS16660
gene id: 369723:STROP_RS16660
uniprot id: A4XA18
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

369723:STROP RS01565
gene id: 369723:STROP_RS01565
uniprot id: A4X1P5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Homodimer.

369723:STROP RS06080
gene id: 369723:STROP_RS06080
uniprot id: A4X477
names: Similarity
messages: Belongs to the TPP enzyme family.

369723:STROP RS07555
gene id: 369723:STROP_RS07555
uniprot id: A4X520
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

369723:STROP RS03960
gene id: 369723:STROP_RS03960
uniprot id: A4X309
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

369723:STROP RS17295
gene id: 369723:STROP_RS17295
uniprot id: A4XAC9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

369723:STROP RS10650
gene id: 369723:STROP_RS10650
uniprot id: A4X6R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methyltransferase superfamily. EgtD family.
messages: Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.
messages: Monomer.

369723:STROP RS21230
gene id: 369723:STROP_RS21230
uniprot id: A4XCI2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

369723:STROP RS15525
gene id: 369723:STROP_RS15525
uniprot id: A4XDR7
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

369723:STROP RS05535
gene id: 369723:STROP_RS05535
uniprot id: A4X3W8
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

369723:STROP RS07060
gene id: 369723:STROP_RS07060
uniprot id: A4X4S2
names: Function
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.
messages: Specifically hydrolyzes (R)-S-adenosyl-L-methionine ((R)-SAM), the inactive form of the ubiquitous cofactor SAM, into adenosine and L-methionine. Is stereoselective as it cannot use the active form of SAM, (S)-S-adenosyl-L-methionine, as substrate. Likely plays a role in preventing accumulation of (R)-S-adenosyl-L-methionine in cells; maintenance of (S)-S-denosyl-L-methionine homochirality is important for cellular health given that the (R)-form is largely inactive as a methyl donor and can function as an inhibitor of methyltransferases.

369723:STROP RS11610
gene id: 369723:STROP_RS11610
uniprot id: A4X7A7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01370
gene id: 369723:STROP_RS01370
uniprot id: A4X1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

369723:STROP RS00875
gene id: 369723:STROP_RS00875
uniprot id: A4X1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

369723:STROP RS09300
gene id: 369723:STROP_RS09300
uniprot id: A4X608
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS01415
gene id: 369723:STROP_RS01415
uniprot id: A4X1L3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

369723:STROP RS14545
gene id: 369723:STROP_RS14545
uniprot id: A4X8Z1
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

369723:STROP RS13885
gene id: 369723:STROP_RS13885
uniprot id: A4X8K7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11950
gene id: 369723:STROP_RS11950
uniprot id: A4X7H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

369723:STROP RS02005
gene id: 369723:STROP_RS02005
uniprot id: A4X1Y3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS04270
gene id: 369723:STROP_RS04270
uniprot id: A4X370
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS08540
gene id: 369723:STROP_RS08540
uniprot id: A4X5K7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

369723:STROP RS07910
gene id: 369723:STROP_RS07910
uniprot id: A4X588
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS04190
gene id: 369723:STROP_RS04190
uniprot id: A4X354
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS14765
gene id: 369723:STROP_RS14765
uniprot id: A4X927
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

369723:STROP RS09530
gene id: 369723:STROP_RS09530
uniprot id: A4X654
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS11255
gene id: 369723:STROP_RS11255
uniprot id: A4X738
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

369723:STROP RS00735
gene id: 369723:STROP_RS00735
uniprot id: A4X182
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

369723:STROP RS15905
gene id: 369723:STROP_RS15905
uniprot id: A4X9N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

369723:STROP RS03585
gene id: 369723:STROP_RS03585
uniprot id: A4X2T7
names: Similarity
messages: Belongs to the peptidase M17 family.

369723:STROP RS02965
gene id: 369723:STROP_RS02965
uniprot id: A4X2G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

369723:STROP RS18540
gene id: 369723:STROP_RS18540
uniprot id: A4XB21
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS22495
gene id: 369723:STROP_RS22495
uniprot id: A4XD76
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS06100
gene id: 369723:STROP_RS06100
uniprot id: A4X481
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

369723:STROP RS23105
gene id: 369723:STROP_RS23105
uniprot id: A4XDI9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS05480
gene id: 369723:STROP_RS05480
uniprot id: A4X3V7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS21475
gene id: 369723:STROP_RS21475
uniprot id: A4XCM9
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

369723:STROP RS10400
gene id: 369723:STROP_RS10400
uniprot id: A4X6L7
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

369723:STROP RS09120
gene id: 369723:STROP_RS09120
uniprot id: A4X5X2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

369723:STROP RS19145
gene id: 369723:STROP_RS19145
uniprot id: A4XBD8
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

369723:STROP RS14325
gene id: 369723:STROP_RS14325
uniprot id: A4X8U6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

369723:STROP RS16035
gene id: 369723:STROP_RS16035
uniprot id: A4XDN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

369723:STROP RS08480
gene id: 369723:STROP_RS08480
uniprot id: A4X5J5
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

369723:STROP RS18795
gene id: 369723:STROP_RS18795
uniprot id: A4XB71
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

369723:STROP RS11855
gene id: 369723:STROP_RS11855
uniprot id: A4X7F5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

369723:STROP RS08430
gene id: 369723:STROP_RS08430
uniprot id: A4X5I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS06595
gene id: 369723:STROP_RS06595
uniprot id: A4X4H7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

369723:STROP RS00755
gene id: 369723:STROP_RS00755
uniprot id: A4X186
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

369723:STROP RS21345
gene id: 369723:STROP_RS21345
uniprot id: A4XCK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS09035
gene id: 369723:STROP_RS09035
uniprot id: A4X5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

369723:STROP RS06885
gene id: 369723:STROP_RS06885
uniprot id: A4X4N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

369723:STROP RS19780
gene id: 369723:STROP_RS19780
uniprot id: A4XBQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

369723:STROP RS15490
gene id: 369723:STROP_RS15490
uniprot id: A4X9G4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

369723:STROP RS19505
gene id: 369723:STROP_RS19505
uniprot id: A4XBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS15445
gene id: 369723:STROP_RS15445
uniprot id: A4X9F5
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS00195
gene id: 369723:STROP_RS00195
uniprot id: A4X0X4
names: Similarity
messages: Belongs to the peptidase S8 family.

369723:STROP RS09045
gene id: 369723:STROP_RS09045
uniprot id: A4X5V7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11295
gene id: 369723:STROP_RS11295
uniprot id: A4X746
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

369723:STROP RS16075
gene id: 369723:STROP_RS16075
uniprot id: A4X9R3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

369723:STROP RS14665
gene id: 369723:STROP_RS14665
uniprot id: A4X914
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS10660
gene id: 369723:STROP_RS10660
uniprot id: A4X6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

369723:STROP RS03860
gene id: 369723:STROP_RS03860
uniprot id: A4X2Y9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19335
gene id: 369723:STROP_RS19335
uniprot id: A4XDK8
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

369723:STROP RS00445
gene id: 369723:STROP_RS00445
uniprot id: A4X124
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS02170
gene id: 369723:STROP_RS02170
uniprot id: A4X214
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS18220
gene id: 369723:STROP_RS18220
uniprot id: A4XAV6
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

369723:STROP RS26035
gene id: 369723:STROP_RS26035
uniprot id: A4X8G7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

369723:STROP RS02970
gene id: 369723:STROP_RS02970
uniprot id: A4X2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

369723:STROP RS05070
gene id: 369723:STROP_RS05070
uniprot id: A4X3M6
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

369723:STROP RS11515
gene id: 369723:STROP_RS11515
uniprot id: A4X789
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18420
gene id: 369723:STROP_RS18420
uniprot id: A4XAZ7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS08900
gene id: 369723:STROP_RS08900
uniprot id: A4X5S8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS03965
gene id: 369723:STROP_RS03965
uniprot id: A4X310
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

369723:STROP RS08130
gene id: 369723:STROP_RS08130
uniprot id: A4X5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

369723:STROP RS07000
gene id: 369723:STROP_RS07000
uniprot id: A4X4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

369723:STROP RS13135
gene id: 369723:STROP_RS13135
uniprot id: A4X854
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS20730
gene id: 369723:STROP_RS20730
uniprot id: A4XC86
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

369723:STROP RS01965
gene id: 369723:STROP_RS01965
uniprot id: A4X1X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS13175
gene id: 369723:STROP_RS13175
uniprot id: A4X862
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS00730
gene id: 369723:STROP_RS00730
uniprot id: A4X181
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS07905
gene id: 369723:STROP_RS07905
uniprot id: A4X587
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS04375
gene id: 369723:STROP_RS04375
uniprot id: A4X390
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS23080
gene id: 369723:STROP_RS23080
uniprot id: A4XDI4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS25425
gene id: 369723:STROP_RS25425
uniprot id: A4XDR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS21820
gene id: 369723:STROP_RS21820
uniprot id: A4XCU7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS20040
gene id: 369723:STROP_RS20040
uniprot id: A4XBV4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS06555
gene id: 369723:STROP_RS06555
uniprot id: A4X4G9
names: Similarity
messages: Belongs to the P(II) protein family.

369723:STROP RS11235
gene id: 369723:STROP_RS11235
uniprot id: A4X734
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS01460
gene id: 369723:STROP_RS01460
uniprot id: A4X1M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

369723:STROP RS17395
gene id: 369723:STROP_RS17395
uniprot id: A4XAE7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

369723:STROP RS18360
gene id: 369723:STROP_RS18360
uniprot id: A4XAY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

369723:STROP RS09385
gene id: 369723:STROP_RS09385
uniprot id: A4X625
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS01295
gene id: 369723:STROP_RS01295
uniprot id: A4X1I9
names: Similarity
messages: Belongs to the AAA ATPase family.

369723:STROP RS16825
gene id: 369723:STROP_RS16825
uniprot id: A4XA50
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

369723:STROP RS00905
gene id: 369723:STROP_RS00905
uniprot id: A4X1B5
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS22800
gene id: 369723:STROP_RS22800
uniprot id: A4XDD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

369723:STROP RS02215
gene id: 369723:STROP_RS02215
uniprot id: A4X223
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

369723:STROP RS04800
gene id: 369723:STROP_RS04800
uniprot id: A4X3H4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

369723:STROP RS20355
gene id: 369723:STROP_RS20355
uniprot id: A4XC12
names: Similarity
messages: Belongs to the GSP E family.

369723:STROP RS05060
gene id: 369723:STROP_RS05060
uniprot id: A4X3M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

369723:STROP RS17150
gene id: 369723:STROP_RS17150
uniprot id: A4XAA1
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS00005
gene id: 369723:STROP_RS00005
uniprot id: A4X0T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

369723:STROP RS01480
gene id: 369723:STROP_RS01480
uniprot id: A4X1M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. MshD subfamily.
messages: Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
messages: Monomer.

369723:STROP RS08255
gene id: 369723:STROP_RS08255
uniprot id: A4X5F2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

369723:STROP RS06085
gene id: 369723:STROP_RS06085
uniprot id: A4X478
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS16180
gene id: 369723:STROP_RS16180
uniprot id: A4X9T4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

369723:STROP RS23070
gene id: 369723:STROP_RS23070
uniprot id: A4XDI2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

369723:STROP RS12675
gene id: 369723:STROP_RS12675
uniprot id: A4X7W3
names: Similarity
messages: Belongs to the CobH/CbiC family.

369723:STROP RS01450
gene id: 369723:STROP_RS01450
uniprot id: A4X1M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

369723:STROP RS16165
gene id: 369723:STROP_RS16165
uniprot id: A4X9T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

369723:STROP RS06395
gene id: 369723:STROP_RS06395
uniprot id: A4X4D7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

369723:STROP RS06485
gene id: 369723:STROP_RS06485
uniprot id: A4X4F5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

369723:STROP RS20660
gene id: 369723:STROP_RS20660
uniprot id: A4XC73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS05575
gene id: 369723:STROP_RS05575
uniprot id: A4X3X6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

369723:STROP RS15635
gene id: 369723:STROP_RS15635
uniprot id: A4X9I4
names: Subcellular Location Annotation
messages: Cytoplasm

369723:STROP RS15340
gene id: 369723:STROP_RS15340
uniprot id: A4X9D4
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

369723:STROP RS05580
gene id: 369723:STROP_RS05580
uniprot id: A4X3X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

369723:STROP RS18680
gene id: 369723:STROP_RS18680
uniprot id: A4XB50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

369723:STROP RS18600
gene id: 369723:STROP_RS18600
uniprot id: A4XB33
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

369723:STROP RS01790
gene id: 369723:STROP_RS01790
uniprot id: A4X1U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

369723:STROP RS15415
gene id: 369723:STROP_RS15415
uniprot id: A4X9E9
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

369723:STROP RS05380
gene id: 369723:STROP_RS05380
uniprot id: A4X3T7
names: Similarity
messages: Belongs to the peptidase S33 family.

369723:STROP RS17655
gene id: 369723:STROP_RS17655
uniprot id: A4XAJ4
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

369723:STROP RS20420
gene id: 369723:STROP_RS20420
uniprot id: A4XC25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS06515
gene id: 369723:STROP_RS06515
uniprot id: A4X4G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

369723:STROP RS11360
gene id: 369723:STROP_RS11360
uniprot id: A4X758
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS04870
gene id: 369723:STROP_RS04870
uniprot id: A4X3I8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

369723:STROP RS21485
gene id: 369723:STROP_RS21485
uniprot id: A4XCN1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

369723:STROP RS11270
gene id: 369723:STROP_RS11270
uniprot id: A4X741
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

369723:STROP RS22225
gene id: 369723:STROP_RS22225
uniprot id: A4XD25
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

369723:STROP RS12160
gene id: 369723:STROP_RS12160
uniprot id: A4X7L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS23000
gene id: 369723:STROP_RS23000
uniprot id: A4XDG8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

369723:STROP RS04330
gene id: 369723:STROP_RS04330
uniprot id: A4X381
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS04030
gene id: 369723:STROP_RS04030
uniprot id: A4X322
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

369723:STROP RS16945
gene id: 369723:STROP_RS16945
uniprot id: A4XA66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

369723:STROP RS06645
gene id: 369723:STROP_RS06645
uniprot id: A4X4I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

369723:STROP RS16205
gene id: 369723:STROP_RS16205
uniprot id: A4X9T9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

369723:STROP RS09305
gene id: 369723:STROP_RS09305
uniprot id: A4X609
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS12710
gene id: 369723:STROP_RS12710
uniprot id: A4X7X0
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

369723:STROP RS17475
gene id: 369723:STROP_RS17475
uniprot id: A4XAG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

369723:STROP RS15380
gene id: 369723:STROP_RS15380
uniprot id: A4X9E2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS18850
gene id: 369723:STROP_RS18850
uniprot id: A4XB81
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

369723:STROP RS13205
gene id: 369723:STROP_RS13205
uniprot id: A4X868
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS13470
gene id: 369723:STROP_RS13470
uniprot id: A4X8C2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS07075
gene id: 369723:STROP_RS07075
uniprot id: A4X4S5
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

369723:STROP RS16090
gene id: 369723:STROP_RS16090
uniprot id: A4X9R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS17375
gene id: 369723:STROP_RS17375
uniprot id: A4XAE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

369723:STROP RS14315
gene id: 369723:STROP_RS14315
uniprot id: A4X8U4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

369723:STROP RS06980
gene id: 369723:STROP_RS06980
uniprot id: A4X4Q6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

369723:STROP RS04080
gene id: 369723:STROP_RS04080
uniprot id: A4X332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS02025
gene id: 369723:STROP_RS02025
uniprot id: A4X1Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS21440
gene id: 369723:STROP_RS21440
uniprot id: A4XCM2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS22140
gene id: 369723:STROP_RS22140
uniprot id: A4XD08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

369723:STROP RS09390
gene id: 369723:STROP_RS09390
uniprot id: A4X626
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

369723:STROP RS17515
gene id: 369723:STROP_RS17515
uniprot id: A4XAH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

369723:STROP RS07995
gene id: 369723:STROP_RS07995
uniprot id: A4X5A0
names: Similarity
messages: Belongs to the CapA family.

369723:STROP RS16285
gene id: 369723:STROP_RS16285
uniprot id: A4X9V4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

369723:STROP RS19715
gene id: 369723:STROP_RS19715
uniprot id: A4XBP2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

369723:STROP RS13340
gene id: 369723:STROP_RS13340
uniprot id: A4X895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS05660
gene id: 369723:STROP_RS05660
uniprot id: A4X3Z2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

369723:STROP RS10750
gene id: 369723:STROP_RS10750
uniprot id: A4X6T7
names: Similarity
messages: Belongs to the citrate synthase family.

369723:STROP RS13875
gene id: 369723:STROP_RS13875
uniprot id: A4X8K5
names: Similarity
messages: Belongs to the thioesterase family.

369723:STROP RS08750
gene id: 369723:STROP_RS08750
uniprot id: A4X5P9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

369723:STROP RS18130
gene id: 369723:STROP_RS18130
uniprot id: A4XAT8
names: Similarity
messages: Belongs to the arginase family.

369723:STROP RS06495
gene id: 369723:STROP_RS06495
uniprot id: A4X4F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

369723:STROP RS06245
gene id: 369723:STROP_RS06245
uniprot id: A4X4B0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS06875
gene id: 369723:STROP_RS06875
uniprot id: A4X4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

369723:STROP RS17225
gene id: 369723:STROP_RS17225
uniprot id: A4XAB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS16140
gene id: 369723:STROP_RS16140
uniprot id: A4X9S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

369723:STROP RS00075
gene id: 369723:STROP_RS00075
uniprot id: A4X0V0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

369723:STROP RS22505
gene id: 369723:STROP_RS22505
uniprot id: A4XD78
names: Similarity
messages: Belongs to the GSP E family.

369723:STROP RS18980
gene id: 369723:STROP_RS18980
uniprot id: A4XBA7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01115
gene id: 369723:STROP_RS01115
uniprot id: A4X1F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS06620
gene id: 369723:STROP_RS06620
uniprot id: A4X4I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

369723:STROP RS19685
gene id: 369723:STROP_RS19685
uniprot id: A4XBN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

369723:STROP RS12825
gene id: 369723:STROP_RS12825
uniprot id: A4X7Z3
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

369723:STROP RS17305
gene id: 369723:STROP_RS17305
uniprot id: A4XAD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

369723:STROP RS05585
gene id: 369723:STROP_RS05585
uniprot id: A4X3X8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

369723:STROP RS05440
gene id: 369723:STROP_RS05440
uniprot id: A4X3U9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS16810
gene id: 369723:STROP_RS16810
uniprot id: A4XA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS14675
gene id: 369723:STROP_RS14675
uniprot id: A4X916
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

369723:STROP RS12790
gene id: 369723:STROP_RS12790
uniprot id: A4X7Y6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

369723:STROP RS16085
gene id: 369723:STROP_RS16085
uniprot id: A4X9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

369723:STROP RS09550
gene id: 369723:STROP_RS09550
uniprot id: A4X658
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

369723:STROP RS19080
gene id: 369723:STROP_RS19080
uniprot id: A4XBC6
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

369723:STROP RS10735
gene id: 369723:STROP_RS10735
uniprot id: A4X6T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

369723:STROP RS05985
gene id: 369723:STROP_RS05985
uniprot id: A4X459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS10030
gene id: 369723:STROP_RS10030
uniprot id: A4X6E2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

369723:STROP RS16620
gene id: 369723:STROP_RS16620
uniprot id: A4XA11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

369723:STROP RS03770
gene id: 369723:STROP_RS03770
uniprot id: A4X2X3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

369723:STROP RS16585
gene id: 369723:STROP_RS16585
uniprot id: A4XA04
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

369723:STROP RS01440
gene id: 369723:STROP_RS01440
uniprot id: A4X1L8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS14305
gene id: 369723:STROP_RS14305
uniprot id: A4X8U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS14020
gene id: 369723:STROP_RS14020
uniprot id: A4X8N4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS04735
gene id: 369723:STROP_RS04735
uniprot id: A4X3G1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS03445
gene id: 369723:STROP_RS03445
uniprot id: A4X2Q8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

369723:STROP RS20560
gene id: 369723:STROP_RS20560
uniprot id: A4XC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

369723:STROP RS04075
gene id: 369723:STROP_RS04075
uniprot id: A4X331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS07665
gene id: 369723:STROP_RS07665
uniprot id: A4X540
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS13335
gene id: 369723:STROP_RS13335
uniprot id: A4X894
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS06880
gene id: 369723:STROP_RS06880
uniprot id: A4X4N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

369723:STROP RS15520
gene id: 369723:STROP_RS15520
uniprot id: A4XDR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

369723:STROP RS04165
gene id: 369723:STROP_RS04165
uniprot id: A4X349
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS04885
gene id: 369723:STROP_RS04885
uniprot id: A4X3J0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12260
gene id: 369723:STROP_RS12260
uniprot id: A4X7N4
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

369723:STROP RS05170
gene id: 369723:STROP_RS05170
uniprot id: A4X3P5
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS16340
gene id: 369723:STROP_RS16340
uniprot id: A4X9V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS11215
gene id: 369723:STROP_RS11215
uniprot id: A4X730
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

369723:STROP RS09510
gene id: 369723:STROP_RS09510
uniprot id: A4X650
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

369723:STROP RS19405
gene id: 369723:STROP_RS19405
uniprot id: A4XBI1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS15570
gene id: 369723:STROP_RS15570
uniprot id: A4X9H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

369723:STROP RS23160
gene id: 369723:STROP_RS23160
uniprot id: A4XDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

369723:STROP RS10395
gene id: 369723:STROP_RS10395
uniprot id: A4X6L6
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

369723:STROP RS07270
gene id: 369723:STROP_RS07270
uniprot id: A4X4W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

369723:STROP RS17725
gene id: 369723:STROP_RS17725
uniprot id: A4XAK8
names: Similarity
messages: Belongs to the acetaldehyde dehydrogenase family.

369723:STROP RS12845
gene id: 369723:STROP_RS12845
uniprot id: A4X7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

369723:STROP RS20640
gene id: 369723:STROP_RS20640
uniprot id: A4XC69
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS09660
gene id: 369723:STROP_RS09660
uniprot id: A4X675
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

369723:STROP RS17280
gene id: 369723:STROP_RS17280
uniprot id: A4XAC6
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS06585
gene id: 369723:STROP_RS06585
uniprot id: A4X4H5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

369723:STROP RS18270
gene id: 369723:STROP_RS18270
uniprot id: A4XAW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

369723:STROP RS06560
gene id: 369723:STROP_RS06560
uniprot id: A4X4H0
names: Activity Regulation
names: Caution
names: Domain
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

369723:STROP RS09505
gene id: 369723:STROP_RS09505
uniprot id: A4X649
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

369723:STROP RS16465
gene id: 369723:STROP_RS16465
uniprot id: A4X9Y1
names: Similarity
messages: Belongs to the RelA/SpoT family.

369723:STROP RS10930
gene id: 369723:STROP_RS10930
uniprot id: A4X6X3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01420
gene id: 369723:STROP_RS01420
uniprot id: A4X1L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

369723:STROP RS19760
gene id: 369723:STROP_RS19760
uniprot id: A4XBQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

369723:STROP RS01215
gene id: 369723:STROP_RS01215
uniprot id: A4X1H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS15680
gene id: 369723:STROP_RS15680
uniprot id: A4X9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

369723:STROP RS17935
gene id: 369723:STROP_RS17935
uniprot id: A4XAP9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS09710
gene id: 369723:STROP_RS09710
uniprot id: A4X685
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

369723:STROP RS04730
gene id: 369723:STROP_RS04730
uniprot id: A4X3G0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

369723:STROP RS01880
gene id: 369723:STROP_RS01880
uniprot id: A4X1V8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS21530
gene id: 369723:STROP_RS21530
uniprot id: A4XCP0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

369723:STROP RS13510
gene id: 369723:STROP_RS13510
uniprot id: A4X8D0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

369723:STROP RS07420
gene id: 369723:STROP_RS07420
uniprot id: A4X4Z2
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

369723:STROP RS18215
gene id: 369723:STROP_RS18215
uniprot id: A4XAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS06435
gene id: 369723:STROP_RS06435
uniprot id: A4X4E5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

369723:STROP RS22705
gene id: 369723:STROP_RS22705
uniprot id: A4XDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

369723:STROP RS16385
gene id: 369723:STROP_RS16385
uniprot id: A4X9W5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

369723:STROP RS15305
gene id: 369723:STROP_RS15305
uniprot id: A4X9C7
names: Similarity
messages: Belongs to the asparagine synthetase family.

369723:STROP RS04470
gene id: 369723:STROP_RS04470
uniprot id: A4X3A9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

369723:STROP RS22120
gene id: 369723:STROP_RS22120
uniprot id: A4XD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS22420
gene id: 369723:STROP_RS22420
uniprot id: A4XD61
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

369723:STROP RS16065
gene id: 369723:STROP_RS16065
uniprot id: A4X9R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

369723:STROP RS19290
gene id: 369723:STROP_RS19290
uniprot id: A4XBG6
names: Similarity
messages: Belongs to the peptidase M1 family.

369723:STROP RS13550
gene id: 369723:STROP_RS13550
uniprot id: A4X8D8
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS05990
gene id: 369723:STROP_RS05990
uniprot id: A4X460
names: Subcellular Location Annotation
messages: cytosol

369723:STROP RS21885
gene id: 369723:STROP_RS21885
uniprot id: A4XCV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS03395
gene id: 369723:STROP_RS03395
uniprot id: A4X2P8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS16700
gene id: 369723:STROP_RS16700
uniprot id: A4XA26
names: Similarity
messages: Belongs to the glutamine synthetase family.

369723:STROP RS03185
gene id: 369723:STROP_RS03185
uniprot id: A4X2K7
names: Subcellular Location Annotation
messages: Cytoplasm

369723:STROP RS22675
gene id: 369723:STROP_RS22675
uniprot id: A4XDB2
names: Similarity
messages: Belongs to the FPG family.

369723:STROP RS22415
gene id: 369723:STROP_RS22415
uniprot id: A4XD60
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

369723:STROP RS05540
gene id: 369723:STROP_RS05540
uniprot id: A4X3W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

369723:STROP RS18950
gene id: 369723:STROP_RS18950
uniprot id: A4XBA1
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

369723:STROP RS13665
gene id: 369723:STROP_RS13665
uniprot id: A4X8G3
names: Similarity
messages: Belongs to the YciI family.

369723:STROP RS19590
gene id: 369723:STROP_RS19590
uniprot id: A4XBL7
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

369723:STROP RS07320
gene id: 369723:STROP_RS07320
uniprot id: A4X4X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DtxR/MntR family.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS05010
gene id: 369723:STROP_RS05010
uniprot id: A4X3L4
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

369723:STROP RS14330
gene id: 369723:STROP_RS14330
uniprot id: A4X8U7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

369723:STROP RS22950
gene id: 369723:STROP_RS22950
uniprot id: A4XDF9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

369723:STROP RS21740
gene id: 369723:STROP_RS21740
uniprot id: A4XCT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

369723:STROP RS04380
gene id: 369723:STROP_RS04380
uniprot id: A4X391
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

369723:STROP RS13750
gene id: 369723:STROP_RS13750
uniprot id: A4X8I1
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

369723:STROP RS10250
gene id: 369723:STROP_RS10250
uniprot id: A4X6I6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

369723:STROP RS18615
gene id: 369723:STROP_RS18615
uniprot id: A4XB36
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

369723:STROP RS20480
gene id: 369723:STROP_RS20480
uniprot id: A4XC37
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS21790
gene id: 369723:STROP_RS21790
uniprot id: A4XCU1
names: Similarity
messages: Belongs to the CapA family.

369723:STROP RS17575
gene id: 369723:STROP_RS17575
uniprot id: A4XAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

369723:STROP RS14855
gene id: 369723:STROP_RS14855
uniprot id: A4X946
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

369723:STROP RS03855
gene id: 369723:STROP_RS03855
uniprot id: A4X2Y8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12220
gene id: 369723:STROP_RS12220
uniprot id: A4X7M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS13185
gene id: 369723:STROP_RS13185
uniprot id: A4X864
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

369723:STROP RS21095
gene id: 369723:STROP_RS21095
uniprot id: A4XCF6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS06915
gene id: 369723:STROP_RS06915
uniprot id: A4X4P3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS09745
gene id: 369723:STROP_RS09745
uniprot id: A4X692
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

369723:STROP RS06825
gene id: 369723:STROP_RS06825
uniprot id: A4X4M4
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01030
gene id: 369723:STROP_RS01030
uniprot id: A4X1D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

369723:STROP RS04920
gene id: 369723:STROP_RS04920
uniprot id: A4X3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

369723:STROP RS20485
gene id: 369723:STROP_RS20485
uniprot id: A4XC38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS00395
gene id: 369723:STROP_RS00395
uniprot id: A4X113
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS16335
gene id: 369723:STROP_RS16335
uniprot id: A4X9V5
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

369723:STROP RS11130
gene id: 369723:STROP_RS11130
uniprot id: A4X714
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

369723:STROP RS21555
gene id: 369723:STROP_RS21555
uniprot id: A4XCP5
names: Similarity
messages: Belongs to the Nth/MutY family.

369723:STROP RS03905
gene id: 369723:STROP_RS03905
uniprot id: A4X2Z8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS10095
gene id: 369723:STROP_RS10095
uniprot id: A4X6F5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

369723:STROP RS16280
gene id: 369723:STROP_RS16280
uniprot id: A4X9V3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

369723:STROP RS07415
gene id: 369723:STROP_RS07415
uniprot id: A4X4Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

369723:STROP RS12875
gene id: 369723:STROP_RS12875
uniprot id: A4X803
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

369723:STROP RS16525
gene id: 369723:STROP_RS16525
uniprot id: A4X9Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

369723:STROP RS10645
gene id: 369723:STROP_RS10645
uniprot id: A4X6R6
names: Function
messages: Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

369723:STROP RS06975
gene id: 369723:STROP_RS06975
uniprot id: A4X4Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

369723:STROP RS01250
gene id: 369723:STROP_RS01250
uniprot id: A4X1I0
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

369723:STROP RS06130
gene id: 369723:STROP_RS06130
uniprot id: A4X487
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

369723:STROP RS14410
gene id: 369723:STROP_RS14410
uniprot id: A4X8W3
names: Similarity
messages: Belongs to the peptidase M7 family.

369723:STROP RS11730
gene id: 369723:STROP_RS11730
uniprot id: A4X7D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

369723:STROP RS01035
gene id: 369723:STROP_RS01035
uniprot id: A4X1D8
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

369723:STROP RS09345
gene id: 369723:STROP_RS09345
uniprot id: A4X617
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

369723:STROP RS21330
gene id: 369723:STROP_RS21330
uniprot id: A4XCK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS13910
gene id: 369723:STROP_RS13910
uniprot id: A4X8L2
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS16320
gene id: 369723:STROP_RS16320
uniprot id: A4XDN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

369723:STROP RS16745
gene id: 369723:STROP_RS16745
uniprot id: A4XA35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

369723:STROP RS22980
gene id: 369723:STROP_RS22980
uniprot id: A4XDG4
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

369723:STROP RS04680
gene id: 369723:STROP_RS04680
uniprot id: A4X3F0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

369723:STROP RS05225
gene id: 369723:STROP_RS05225
uniprot id: A4X3Q6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

369723:STROP RS18935
gene id: 369723:STROP_RS18935
uniprot id: A4XB98
names: Similarity
messages: Belongs to the peptidase U62 family.

369723:STROP RS20300
gene id: 369723:STROP_RS20300
uniprot id: A4XC00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

369723:STROP RS01465
gene id: 369723:STROP_RS01465
uniprot id: A4X1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

369723:STROP RS07325
gene id: 369723:STROP_RS07325
uniprot id: A4X4X3
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

369723:STROP RS04020
gene id: 369723:STROP_RS04020
uniprot id: A4X320
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

369723:STROP RS02495
gene id: 369723:STROP_RS02495
uniprot id: A4X279
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

369723:STROP RS12205
gene id: 369723:STROP_RS12205
uniprot id: A4X7M3
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

369723:STROP RS14935
gene id: 369723:STROP_RS14935
uniprot id: A4X962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS18175
gene id: 369723:STROP_RS18175
uniprot id: A4XAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

369723:STROP RS09455
gene id: 369723:STROP_RS09455
uniprot id: A4X639
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

369723:STROP RS09395
gene id: 369723:STROP_RS09395
uniprot id: A4X627
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS13130
gene id: 369723:STROP_RS13130
uniprot id: A4X853
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS22430
gene id: 369723:STROP_RS22430
uniprot id: A4XD63
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

369723:STROP RS18900
gene id: 369723:STROP_RS18900
uniprot id: A4XB91
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

369723:STROP RS09125
gene id: 369723:STROP_RS09125
uniprot id: A4X5X3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

369723:STROP RS22410
gene id: 369723:STROP_RS22410
uniprot id: A4XD59
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IPP isomerase type 1 family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Cytoplasm

369723:STROP RS14050
gene id: 369723:STROP_RS14050
uniprot id: A4X8P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

369723:STROP RS12585
gene id: 369723:STROP_RS12585
uniprot id: A4X7U6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS17410
gene id: 369723:STROP_RS17410
uniprot id: A4XAF0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11300
gene id: 369723:STROP_RS11300
uniprot id: A4X747
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

369723:STROP RS09365
gene id: 369723:STROP_RS09365
uniprot id: A4X621
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

369723:STROP RS13720
gene id: 369723:STROP_RS13720
uniprot id: A4X8H5
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

369723:STROP RS17255
gene id: 369723:STROP_RS17255
uniprot id: A4XAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS19630
gene id: 369723:STROP_RS19630
uniprot id: A4XBM5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS15435
gene id: 369723:STROP_RS15435
uniprot id: A4X9F3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

369723:STROP RS18255
gene id: 369723:STROP_RS18255
uniprot id: A4XAW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

369723:STROP RS09695
gene id: 369723:STROP_RS09695
uniprot id: A4X682
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS01810
gene id: 369723:STROP_RS01810
uniprot id: A4X1U4
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

369723:STROP RS06045
gene id: 369723:STROP_RS06045
uniprot id: A4X470
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

369723:STROP RS08215
gene id: 369723:STROP_RS08215
uniprot id: A4X5E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

369723:STROP RS09215
gene id: 369723:STROP_RS09215
uniprot id: A4X5Z0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

369723:STROP RS07480
gene id: 369723:STROP_RS07480
uniprot id: A4X504
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

369723:STROP RS11495
gene id: 369723:STROP_RS11495
uniprot id: A4X785
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

369723:STROP RS14940
gene id: 369723:STROP_RS14940
uniprot id: A4X963
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS08495
gene id: 369723:STROP_RS08495
uniprot id: A4X5J8
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

369723:STROP RS07290
gene id: 369723:STROP_RS07290
uniprot id: A4X4W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

369723:STROP RS16070
gene id: 369723:STROP_RS16070
uniprot id: A4X9R2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

369723:STROP RS14840
gene id: 369723:STROP_RS14840
uniprot id: A4X943
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS02030
gene id: 369723:STROP_RS02030
uniprot id: A4X1Y8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18265
gene id: 369723:STROP_RS18265
uniprot id: A4XAW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

369723:STROP RS05600
gene id: 369723:STROP_RS05600
uniprot id: A4X3Y1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

369723:STROP RS09180
gene id: 369723:STROP_RS09180
uniprot id: A4X5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS15865
gene id: 369723:STROP_RS15865
uniprot id: A4X9M7
names: Similarity
messages: Belongs to the glutamate synthase family.

369723:STROP RS06830
gene id: 369723:STROP_RS06830
uniprot id: A4X4M5
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS16160
gene id: 369723:STROP_RS16160
uniprot id: A4X9T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

369723:STROP RS08245
gene id: 369723:STROP_RS08245
uniprot id: A4X5F0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS18155
gene id: 369723:STROP_RS18155
uniprot id: A4XAU3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

369723:STROP RS09440
gene id: 369723:STROP_RS09440
uniprot id: A4X636
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

369723:STROP RS12295
gene id: 369723:STROP_RS12295
uniprot id: A4X7P1
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

369723:STROP RS17360
gene id: 369723:STROP_RS17360
uniprot id: A4XAE1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS04005
gene id: 369723:STROP_RS04005
uniprot id: A4X317
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

369723:STROP RS15665
gene id: 369723:STROP_RS15665
uniprot id: A4X9I9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS10850
gene id: 369723:STROP_RS10850
uniprot id: A4X6V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.

369723:STROP RS14120
gene id: 369723:STROP_RS14120
uniprot id: A4X8Q4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS05595
gene id: 369723:STROP_RS05595
uniprot id: A4X3Y0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

369723:STROP RS07170
gene id: 369723:STROP_RS07170
uniprot id: A4X4U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS03140
gene id: 369723:STROP_RS03140
uniprot id: A4X2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS17290
gene id: 369723:STROP_RS17290
uniprot id: A4XAC8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

369723:STROP RS11170
gene id: 369723:STROP_RS11170
uniprot id: A4X722
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

369723:STROP RS06800
gene id: 369723:STROP_RS06800
uniprot id: A4X4L9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

369723:STROP RS05055
gene id: 369723:STROP_RS05055
uniprot id: A4X3M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

369723:STROP RS19295
gene id: 369723:STROP_RS19295
uniprot id: A4XBG7
names: Similarity
messages: Belongs to the IMPDH/GMPR family.

369723:STROP RS15825
gene id: 369723:STROP_RS15825
uniprot id: A4X9L9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

369723:STROP RS12065
gene id: 369723:STROP_RS12065
uniprot id: A4X7J4
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.

369723:STROP RS03670
gene id: 369723:STROP_RS03670
uniprot id: A4X2V4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS01745
gene id: 369723:STROP_RS01745
uniprot id: A4X1T2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19370
gene id: 369723:STROP_RS19370
uniprot id: A4XBH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

369723:STROP RS02035
gene id: 369723:STROP_RS02035
uniprot id: A4X1Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

369723:STROP RS21580
gene id: 369723:STROP_RS21580
uniprot id: A4XCQ0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

369723:STROP RS11775
gene id: 369723:STROP_RS11775
uniprot id: A4X7E0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11285
gene id: 369723:STROP_RS11285
uniprot id: A4X744
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

369723:STROP RS15470
gene id: 369723:STROP_RS15470
uniprot id: A4X9G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

369723:STROP RS00010
gene id: 369723:STROP_RS00010
uniprot id: A4X0T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

369723:STROP RS16635
gene id: 369723:STROP_RS16635
uniprot id: A4XA14
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

369723:STROP RS08990
gene id: 369723:STROP_RS08990
uniprot id: A4X5U6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS07260
gene id: 369723:STROP_RS07260
uniprot id: A4X4W1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

369723:STROP RS08275
gene id: 369723:STROP_RS08275
uniprot id: A4X5F6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS17320
gene id: 369723:STROP_RS17320
uniprot id: A4XAD4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

369723:STROP RS18260
gene id: 369723:STROP_RS18260
uniprot id: A4XAW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

369723:STROP RS14960
gene id: 369723:STROP_RS14960
uniprot id: A4X0T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

369723:STROP RS21735
gene id: 369723:STROP_RS21735
uniprot id: A4XCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

369723:STROP RS09480
gene id: 369723:STROP_RS09480
uniprot id: A4X644
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

369723:STROP RS16345
gene id: 369723:STROP_RS16345
uniprot id: A4X9V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS21600
gene id: 369723:STROP_RS21600
uniprot id: A4XCQ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

369723:STROP RS13740
gene id: 369723:STROP_RS13740
uniprot id: A4X8H9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS16555
gene id: 369723:STROP_RS16555
uniprot id: A4X9Z9
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

369723:STROP RS11540
gene id: 369723:STROP_RS11540
uniprot id: A4X794
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

369723:STROP RS17750
gene id: 369723:STROP_RS17750
uniprot id: A4XAL3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS02235
gene id: 369723:STROP_RS02235
uniprot id: A4X227
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.
messages: Reversible hydration of carbon dioxide.

369723:STROP RS05145
gene id: 369723:STROP_RS05145
uniprot id: A4X3P0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

369723:STROP RS17435
gene id: 369723:STROP_RS17435
uniprot id: A4XAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

369723:STROP RS00315
gene id: 369723:STROP_RS00315
uniprot id: A4X0Z6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

369723:STROP RS12075
gene id: 369723:STROP_RS12075
uniprot id: A4X7J6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

369723:STROP RS18670
gene id: 369723:STROP_RS18670
uniprot id: A4XB48
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

369723:STROP RS18240
gene id: 369723:STROP_RS18240
uniprot id: A4XAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

369723:STROP RS21150
gene id: 369723:STROP_RS21150
uniprot id: A4XCG6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

369723:STROP RS12805
gene id: 369723:STROP_RS12805
uniprot id: A4X7Y9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

369723:STROP RS22435
gene id: 369723:STROP_RS22435
uniprot id: A4XD64
names: Similarity
messages: Belongs to the PrpD family.

369723:STROP RS22890
gene id: 369723:STROP_RS22890
uniprot id: A4XDM1
names: Similarity
messages: Belongs to the fructosamine kinase family.

369723:STROP RS06490
gene id: 369723:STROP_RS06490
uniprot id: A4X4F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

369723:STROP RS19480
gene id: 369723:STROP_RS19480
uniprot id: A4XBJ5
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

369723:STROP RS07980
gene id: 369723:STROP_RS07980
uniprot id: A4X597
names: Similarity
messages: Belongs to the universal stress protein A family.

369723:STROP RS04980
gene id: 369723:STROP_RS04980
uniprot id: A4X3K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

369723:STROP RS17190
gene id: 369723:STROP_RS17190
uniprot id: A4XAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCCT transporter (TC 2.A.15) family.
messages: Membrane

369723:STROP RS09470
gene id: 369723:STROP_RS09470
uniprot id: A4X642
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

369723:STROP RS16950
gene id: 369723:STROP_RS16950
uniprot id: A4XA67
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

369723:STROP RS10635
gene id: 369723:STROP_RS10635
uniprot id: A4X6R4
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low-molecular thiol compound ergothioneine.

369723:STROP RS01685
gene id: 369723:STROP_RS01685
uniprot id: A4X1R9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS09655
gene id: 369723:STROP_RS09655
uniprot id: A4X674
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS06940
gene id: 369723:STROP_RS06940
uniprot id: A4X4P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

369723:STROP RS03310
gene id: 369723:STROP_RS03310
uniprot id: A4X2N1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

369723:STROP RS15495
gene id: 369723:STROP_RS15495
uniprot id: A4XDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

369723:STROP RS00140
gene id: 369723:STROP_RS00140
uniprot id: A4X0W3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS18570
gene id: 369723:STROP_RS18570
uniprot id: A4XB27
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

369723:STROP RS10110
gene id: 369723:STROP_RS10110
uniprot id: A4X6F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS06390
gene id: 369723:STROP_RS06390
uniprot id: A4X4D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

369723:STROP RS19585
gene id: 369723:STROP_RS19585
uniprot id: A4XBL6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS19725
gene id: 369723:STROP_RS19725
uniprot id: A4XBP4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

369723:STROP RS00800
gene id: 369723:STROP_RS00800
uniprot id: A4X194
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

369723:STROP RS15515
gene id: 369723:STROP_RS15515
uniprot id: A4XDR5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

369723:STROP RS18610
gene id: 369723:STROP_RS18610
uniprot id: A4XB35
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

369723:STROP RS16695
gene id: 369723:STROP_RS16695
uniprot id: A4XA25
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS07680
gene id: 369723:STROP_RS07680
uniprot id: A4X543
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS10535
gene id: 369723:STROP_RS10535
uniprot id: A4X6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS09405
gene id: 369723:STROP_RS09405
uniprot id: A4X629
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS00565
gene id: 369723:STROP_RS00565
uniprot id: A4X149
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

369723:STROP RS09545
gene id: 369723:STROP_RS09545
uniprot id: A4X657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

369723:STROP RS09355
gene id: 369723:STROP_RS09355
uniprot id: A4X619
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

369723:STROP RS08345
gene id: 369723:STROP_RS08345
uniprot id: A4X5H0
names: Function
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

369723:STROP RS22200
gene id: 369723:STROP_RS22200
uniprot id: A4XD20
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19740
gene id: 369723:STROP_RS19740
uniprot id: A4XBP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

369723:STROP RS20435
gene id: 369723:STROP_RS20435
uniprot id: A4XC28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS15750
gene id: 369723:STROP_RS15750
uniprot id: A4X9K5
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

369723:STROP RS07365
gene id: 369723:STROP_RS07365
uniprot id: A4X4Y1
names: Similarity
messages: Belongs to the peptidase S8 family.

369723:STROP RS02425
gene id: 369723:STROP_RS02425
uniprot id: A4X265
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS01760
gene id: 369723:STROP_RS01760
uniprot id: A4X1T5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS12535
gene id: 369723:STROP_RS12535
uniprot id: A4X7T7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS15510
gene id: 369723:STROP_RS15510
uniprot id: A4XDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

369723:STROP RS19670
gene id: 369723:STROP_RS19670
uniprot id: A4XBN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

369723:STROP RS10490
gene id: 369723:STROP_RS10490
uniprot id: A4X6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS15625
gene id: 369723:STROP_RS15625
uniprot id: A4X9I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

369723:STROP RS04605
gene id: 369723:STROP_RS04605
uniprot id: A4X3D5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS16225
gene id: 369723:STROP_RS16225
uniprot id: A4X9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

369723:STROP RS22300
gene id: 369723:STROP_RS22300
uniprot id: A4XD40
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

369723:STROP RS01975
gene id: 369723:STROP_RS01975
uniprot id: A4X1X7
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

369723:STROP RS22760
gene id: 369723:STROP_RS22760
uniprot id: A4XDD0
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

369723:STROP RS18060
gene id: 369723:STROP_RS18060
uniprot id: A4XAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

369723:STROP RS02285
gene id: 369723:STROP_RS02285
uniprot id: A4X237
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS01940
gene id: 369723:STROP_RS01940
uniprot id: A4X1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

369723:STROP RS02270
gene id: 369723:STROP_RS02270
uniprot id: A4X234
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS17535
gene id: 369723:STROP_RS17535
uniprot id: A4XAH5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

369723:STROP RS21100
gene id: 369723:STROP_RS21100
uniprot id: A4XCF7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS07725
gene id: 369723:STROP_RS07725
uniprot id: A4X552
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

369723:STROP RS07990
gene id: 369723:STROP_RS07990
uniprot id: A4X599
names: Similarity
messages: Belongs to the universal stress protein A family.

369723:STROP RS12450
gene id: 369723:STROP_RS12450
uniprot id: A4X7S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

369723:STROP RS22935
gene id: 369723:STROP_RS22935
uniprot id: A4XDF6
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01945
gene id: 369723:STROP_RS01945
uniprot id: A4X1X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

369723:STROP RS17720
gene id: 369723:STROP_RS17720
uniprot id: A4XAK7
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

369723:STROP RS06835
gene id: 369723:STROP_RS06835
uniprot id: A4X4M6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS21405
gene id: 369723:STROP_RS21405
uniprot id: A4XCL5
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

369723:STROP RS11450
gene id: 369723:STROP_RS11450
uniprot id: A4X776
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

369723:STROP RS00020
gene id: 369723:STROP_RS00020
uniprot id: A4X0U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

369723:STROP RS14115
gene id: 369723:STROP_RS14115
uniprot id: A4X8Q3
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

369723:STROP RS21570
gene id: 369723:STROP_RS21570
uniprot id: A4XCP8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS19755
gene id: 369723:STROP_RS19755
uniprot id: A4XBQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

369723:STROP RS15980
gene id: 369723:STROP_RS15980
uniprot id: A4X9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

369723:STROP RS13920
gene id: 369723:STROP_RS13920
uniprot id: A4X8L4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS12270
gene id: 369723:STROP_RS12270
uniprot id: A4X7N6
names: Function
messages: Acyltransferase required for the direct transfer of medium- to long-chain fatty acyl moieties from a carrier protein (MbtL) on to the epsilon-amino group of lysine residue in the mycobactin core.

369723:STROP RS12990
gene id: 369723:STROP_RS12990
uniprot id: A4X826
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS03430
gene id: 369723:STROP_RS03430
uniprot id: A4X2Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

369723:STROP RS14320
gene id: 369723:STROP_RS14320
uniprot id: A4X8U5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

369723:STROP RS22440
gene id: 369723:STROP_RS22440
uniprot id: A4XD65
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19360
gene id: 369723:STROP_RS19360
uniprot id: A4XDL3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

369723:STROP RS01960
gene id: 369723:STROP_RS01960
uniprot id: A4X1X4
names: Similarity
messages: Belongs to the group II decarboxylase family.

369723:STROP RS23150
gene id: 369723:STROP_RS23150
uniprot id: A4XDJ8
names: Similarity
messages: Belongs to the ParB family.

369723:STROP RS09030
gene id: 369723:STROP_RS09030
uniprot id: A4X5V4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

369723:STROP RS05980
gene id: 369723:STROP_RS05980
uniprot id: A4X458
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS22625
gene id: 369723:STROP_RS22625
uniprot id: A4XDA2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS21325
gene id: 369723:STROP_RS21325
uniprot id: A4XCJ9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

369723:STROP RS15775
gene id: 369723:STROP_RS15775
uniprot id: A4X9L0
names: Similarity
messages: Belongs to the leucine-binding protein family.

369723:STROP RS22220
gene id: 369723:STROP_RS22220
uniprot id: A4XD24
names: Similarity
messages: Belongs to the YciI family.

369723:STROP RS08230
gene id: 369723:STROP_RS08230
uniprot id: A4X5E7
names: Similarity
messages: Belongs to the asparagine synthetase family.

369723:STROP RS11990
gene id: 369723:STROP_RS11990
uniprot id: A4X7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

369723:STROP RS04620
gene id: 369723:STROP_RS04620
uniprot id: A4X3D8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS08910
gene id: 369723:STROP_RS08910
uniprot id: A4X5T0
names: Similarity
messages: Belongs to the type IB topoisomerase family.

369723:STROP RS10265
gene id: 369723:STROP_RS10265
uniprot id: A4X6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

369723:STROP RS12820
gene id: 369723:STROP_RS12820
uniprot id: A4X7Z2
names: Similarity
messages: Belongs to the IucA/IucC family.

369723:STROP RS20345
gene id: 369723:STROP_RS20345
uniprot id: A4XC10
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19565
gene id: 369723:STROP_RS19565
uniprot id: A4XBL2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

369723:STROP RS07840
gene id: 369723:STROP_RS07840
uniprot id: A4X575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS04510
gene id: 369723:STROP_RS04510
uniprot id: A4X3B7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

369723:STROP RS16030
gene id: 369723:STROP_RS16030
uniprot id: A4XDN0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

369723:STROP RS04410
gene id: 369723:STROP_RS04410
uniprot id: A4X397
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS21445
gene id: 369723:STROP_RS21445
uniprot id: A4XCM3
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

369723:STROP RS09600
gene id: 369723:STROP_RS09600
uniprot id: A4X667
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS21595
gene id: 369723:STROP_RS21595
uniprot id: A4XCQ3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

369723:STROP RS21335
gene id: 369723:STROP_RS21335
uniprot id: A4XCK1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

369723:STROP RS09315
gene id: 369723:STROP_RS09315
uniprot id: A4X611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

369723:STROP RS19400
gene id: 369723:STROP_RS19400
uniprot id: A4XBI0
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

369723:STROP RS09225
gene id: 369723:STROP_RS09225
uniprot id: A4X5Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

369723:STROP RS16530
gene id: 369723:STROP_RS16530
uniprot id: A4X9Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

369723:STROP RS10655
gene id: 369723:STROP_RS10655
uniprot id: A4X6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

369723:STROP RS06565
gene id: 369723:STROP_RS06565
uniprot id: A4X4H1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

369723:STROP RS21035
gene id: 369723:STROP_RS21035
uniprot id: A4XCE3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS09490
gene id: 369723:STROP_RS09490
uniprot id: A4X646
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

369723:STROP RS19745
gene id: 369723:STROP_RS19745
uniprot id: A4XBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

369723:STROP RS20630
gene id: 369723:STROP_RS20630
uniprot id: A4XC67
names: Similarity
messages: Belongs to the UbiD family.

369723:STROP RS10785
gene id: 369723:STROP_RS10785
uniprot id: A4X6U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

369723:STROP RS16720
gene id: 369723:STROP_RS16720
uniprot id: A4XA30
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS02490
gene id: 369723:STROP_RS02490
uniprot id: A4X278
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

369723:STROP RS16995
gene id: 369723:STROP_RS16995
uniprot id: A4XA76
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS17185
gene id: 369723:STROP_RS17185
uniprot id: A4XAA7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

369723:STROP RS00860
gene id: 369723:STROP_RS00860
uniprot id: A4X1A6
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS02255
gene id: 369723:STROP_RS02255
uniprot id: A4X231
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11520
gene id: 369723:STROP_RS11520
uniprot id: A4X790
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS10610
gene id: 369723:STROP_RS10610
uniprot id: A4X6Q9
names: Similarity
messages: Belongs to the asparagine synthetase family.

369723:STROP RS03550
gene id: 369723:STROP_RS03550
uniprot id: A4X2S9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

369723:STROP RS07080
gene id: 369723:STROP_RS07080
uniprot id: A4X4S6
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18870
gene id: 369723:STROP_RS18870
uniprot id: A4XB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.

369723:STROP RS06150
gene id: 369723:STROP_RS06150
uniprot id: A4X491
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

369723:STROP RS16045
gene id: 369723:STROP_RS16045
uniprot id: A4XDM6
names: Similarity
messages: Belongs to the UPF0235 family.

369723:STROP RS12705
gene id: 369723:STROP_RS12705
uniprot id: A4X7W9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS09335
gene id: 369723:STROP_RS09335
uniprot id: A4X615
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

369723:STROP RS19035
gene id: 369723:STROP_RS19035
uniprot id: A4XBB7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS02415
gene id: 369723:STROP_RS02415
uniprot id: A4X263
names: Similarity
messages: Belongs to the WXG100 family.

369723:STROP RS14200
gene id: 369723:STROP_RS14200
uniprot id: A4X8S0
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS09485
gene id: 369723:STROP_RS09485
uniprot id: A4X645
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

369723:STROP RS09005
gene id: 369723:STROP_RS09005
uniprot id: A4X5U9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.
messages: Cell membrane
messages: Contains a di-nuclear catalytic Mg(2+) center.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

369723:STROP RS10715
gene id: 369723:STROP_RS10715
uniprot id: A4X6T0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

369723:STROP RS17465
gene id: 369723:STROP_RS17465
uniprot id: A4XAG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS18035
gene id: 369723:STROP_RS18035
uniprot id: A4XAS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS11755
gene id: 369723:STROP_RS11755
uniprot id: A4X7D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

369723:STROP RS07985
gene id: 369723:STROP_RS07985
uniprot id: A4X598
names: Similarity
messages: Belongs to the XFP family.

369723:STROP RS12670
gene id: 369723:STROP_RS12670
uniprot id: A4X7W2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS15845
gene id: 369723:STROP_RS15845
uniprot id: A4X9M3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS05150
gene id: 369723:STROP_RS05150
uniprot id: A4X3P1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS01805
gene id: 369723:STROP_RS01805
uniprot id: A4X1U3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS00480
gene id: 369723:STROP_RS00480
uniprot id: A4X131
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

369723:STROP RS21400
gene id: 369723:STROP_RS21400
uniprot id: A4XCL4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

369723:STROP RS15710
gene id: 369723:STROP_RS15710
uniprot id: A4X9J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

369723:STROP RS22630
gene id: 369723:STROP_RS22630
uniprot id: A4XDA3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

369723:STROP RS05635
gene id: 369723:STROP_RS05635
uniprot id: A4X3Y7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS13490
gene id: 369723:STROP_RS13490
uniprot id: A4X8C6
names: Similarity
messages: Belongs to the AHA1 family.

369723:STROP RS19095
gene id: 369723:STROP_RS19095
uniprot id: A4XBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS16955
gene id: 369723:STROP_RS16955
uniprot id: A4XA68
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

369723:STROP RS13630
gene id: 369723:STROP_RS13630
uniprot id: A4X8F5
names: Similarity
messages: Belongs to the peptidase S33 family.

369723:STROP RS11330
gene id: 369723:STROP_RS11330
uniprot id: A4X752
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

369723:STROP RS21725
gene id: 369723:STROP_RS21725
uniprot id: A4XCS8
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

369723:STROP RS21635
gene id: 369723:STROP_RS21635
uniprot id: A4XCR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS00285
gene id: 369723:STROP_RS00285
uniprot id: A4X0Z1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

369723:STROP RS14990
gene id: 369723:STROP_RS14990
uniprot id: A4X970
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS14030
gene id: 369723:STROP_RS14030
uniprot id: A4X8N6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS12860
gene id: 369723:STROP_RS12860
uniprot id: A4X800
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

369723:STROP RS07020
gene id: 369723:STROP_RS07020
uniprot id: A4X4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

369723:STROP RS04640
gene id: 369723:STROP_RS04640
uniprot id: A4X3E2
names: Similarity
messages: Belongs to the peptidase M42 family.

369723:STROP RS03510
gene id: 369723:STROP_RS03510
uniprot id: A4X2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS08585
gene id: 369723:STROP_RS08585
uniprot id: A4X5L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS10960
gene id: 369723:STROP_RS10960
uniprot id: A4X6X9
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

369723:STROP RS18050
gene id: 369723:STROP_RS18050
uniprot id: A4XAS3
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

369723:STROP RS17570
gene id: 369723:STROP_RS17570
uniprot id: A4XAH9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

369723:STROP RS13150
gene id: 369723:STROP_RS13150
uniprot id: A4X857
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS11035
gene id: 369723:STROP_RS11035
uniprot id: A4X6Z5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS16510
gene id: 369723:STROP_RS16510
uniprot id: A4X9Z0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

369723:STROP RS01175
gene id: 369723:STROP_RS01175
uniprot id: A4X1G5
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

369723:STROP RS20470
gene id: 369723:STROP_RS20470
uniprot id: A4XC35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS19355
gene id: 369723:STROP_RS19355
uniprot id: A4XDL2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS15765
gene id: 369723:STROP_RS15765
uniprot id: A4X9K8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS06095
gene id: 369723:STROP_RS06095
uniprot id: A4X480
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

369723:STROP RS03245
gene id: 369723:STROP_RS03245
uniprot id: A4X2L8
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

369723:STROP RS06470
gene id: 369723:STROP_RS06470
uniprot id: A4X4F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

369723:STROP RS06055
gene id: 369723:STROP_RS06055
uniprot id: A4X472
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

369723:STROP RS00710
gene id: 369723:STROP_RS00710
uniprot id: A4X177
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS01210
gene id: 369723:STROP_RS01210
uniprot id: A4X1H2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS15770
gene id: 369723:STROP_RS15770
uniprot id: A4X9K9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19655
gene id: 369723:STROP_RS19655
uniprot id: A4XBN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

369723:STROP RS13475
gene id: 369723:STROP_RS13475
uniprot id: A4X8C3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS18025
gene id: 369723:STROP_RS18025
uniprot id: A4XAR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

369723:STROP RS17335
gene id: 369723:STROP_RS17335
uniprot id: A4XAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

369723:STROP RS10280
gene id: 369723:STROP_RS10280
uniprot id: A4X6J2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

369723:STROP RS12470
gene id: 369723:STROP_RS12470
uniprot id: A4X7S4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

369723:STROP RS06420
gene id: 369723:STROP_RS06420
uniprot id: A4X4E2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

369723:STROP RS12605
gene id: 369723:STROP_RS12605
uniprot id: A4X7V0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

369723:STROP RS09540
gene id: 369723:STROP_RS09540
uniprot id: A4X656
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS05500
gene id: 369723:STROP_RS05500
uniprot id: A4X3W1
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

369723:STROP RS04665
gene id: 369723:STROP_RS04665
uniprot id: A4X3E7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

369723:STROP RS07035
gene id: 369723:STROP_RS07035
uniprot id: A4X4R7
names: Similarity
messages: Belongs to the PspA/IM30 family.

369723:STROP RS04100
gene id: 369723:STROP_RS04100
uniprot id: A4X336
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS17200
gene id: 369723:STROP_RS17200
uniprot id: A4XAB0
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

369723:STROP RS04955
gene id: 369723:STROP_RS04955
uniprot id: A4X3K4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS18805
gene id: 369723:STROP_RS18805
uniprot id: A4XB73
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS06730
gene id: 369723:STROP_RS06730
uniprot id: A4X4K6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

369723:STROP RS20365
gene id: 369723:STROP_RS20365
uniprot id: A4XC14
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

369723:STROP RS06445
gene id: 369723:STROP_RS06445
uniprot id: A4X4E7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

369723:STROP RS16540
gene id: 369723:STROP_RS16540
uniprot id: A4X9Z6
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

369723:STROP RS09095
gene id: 369723:STROP_RS09095
uniprot id: A4X5W7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11985
gene id: 369723:STROP_RS11985
uniprot id: A4X7I1
names: Similarity
messages: Belongs to the UPF0749 family.

369723:STROP RS15880
gene id: 369723:STROP_RS15880
uniprot id: A4X9N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

369723:STROP RS06105
gene id: 369723:STROP_RS06105
uniprot id: A4X482
names: Subcellular Location Annotation
messages: Cell membrane

369723:STROP RS00670
gene id: 369723:STROP_RS00670
uniprot id: A4X169
names: Similarity
messages: Belongs to the GARS family.

369723:STROP RS04895
gene id: 369723:STROP_RS04895
uniprot id: A4X3J2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

369723:STROP RS00780
gene id: 369723:STROP_RS00780
uniprot id: A4X190
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

369723:STROP RS18845
gene id: 369723:STROP_RS18845
uniprot id: A4XB80
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

369723:STROP RS17470
gene id: 369723:STROP_RS17470
uniprot id: A4XAG2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

369723:STROP RS08875
gene id: 369723:STROP_RS08875
uniprot id: A4X5S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GmhB family.
messages: Cytoplasm

369723:STROP RS11585
gene id: 369723:STROP_RS11585
uniprot id: A4X7A3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS04850
gene id: 369723:STROP_RS04850
uniprot id: A4X3I4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS11905
gene id: 369723:STROP_RS11905
uniprot id: A4X7G5
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS01800
gene id: 369723:STROP_RS01800
uniprot id: A4X1U2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

369723:STROP RS21545
gene id: 369723:STROP_RS21545
uniprot id: A4XCP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

369723:STROP RS19245
gene id: 369723:STROP_RS19245
uniprot id: A4XBF8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12660
gene id: 369723:STROP_RS12660
uniprot id: A4X7W1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

369723:STROP RS18230
gene id: 369723:STROP_RS18230
uniprot id: A4XAV8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

369723:STROP RS06745
gene id: 369723:STROP_RS06745
uniprot id: A4X4K9
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS19150
gene id: 369723:STROP_RS19150
uniprot id: A4XBD9
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

369723:STROP RS17210
gene id: 369723:STROP_RS17210
uniprot id: A4XAB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

369723:STROP RS19320
gene id: 369723:STROP_RS19320
uniprot id: A4XBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

369723:STROP RS17820
gene id: 369723:STROP_RS17820
uniprot id: A4XAM7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS02890
gene id: 369723:STROP_RS02890
uniprot id: A4X2E9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

369723:STROP RS06670
gene id: 369723:STROP_RS06670
uniprot id: A4X4J2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

369723:STROP RS11720
gene id: 369723:STROP_RS11720
uniprot id: A4X7C9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS17165
gene id: 369723:STROP_RS17165
uniprot id: A4XAA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

369723:STROP RS19410
gene id: 369723:STROP_RS19410
uniprot id: A4XBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

369723:STROP RS04010
gene id: 369723:STROP_RS04010
uniprot id: A4X318
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

369723:STROP RS11220
gene id: 369723:STROP_RS11220
uniprot id: A4X731
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS10355
gene id: 369723:STROP_RS10355
uniprot id: A4X6K7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

369723:STROP RS19690
gene id: 369723:STROP_RS19690
uniprot id: A4XBN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

369723:STROP RS02400
gene id: 369723:STROP_RS02400
uniprot id: A4X260
names: Similarity
messages: Belongs to the EccD/Snm4 family.

369723:STROP RS18325
gene id: 369723:STROP_RS18325
uniprot id: A4XAX7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

369723:STROP RS00615
gene id: 369723:STROP_RS00615
uniprot id: A4X159
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS21880
gene id: 369723:STROP_RS21880
uniprot id: A4XCV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS21435
gene id: 369723:STROP_RS21435
uniprot id: A4XCM1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

369723:STROP RS02340
gene id: 369723:STROP_RS02340
uniprot id: A4X248
names: Similarity
messages: Belongs to the peptidase M24B family.

369723:STROP RS18075
gene id: 369723:STROP_RS18075
uniprot id: A4XAS8
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

369723:STROP RS20635
gene id: 369723:STROP_RS20635
uniprot id: A4XC68
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS08240
gene id: 369723:STROP_RS08240
uniprot id: A4X5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS02085
gene id: 369723:STROP_RS02085
uniprot id: A4X1Z7
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

369723:STROP RS09650
gene id: 369723:STROP_RS09650
uniprot id: A4X673
names: Similarity
messages: Belongs to the TlyA family.

369723:STROP RS00680
gene id: 369723:STROP_RS00680
uniprot id: A4X171
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS13345
gene id: 369723:STROP_RS13345
uniprot id: A4X896
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12960
gene id: 369723:STROP_RS12960
uniprot id: A4X820
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

369723:STROP RS18200
gene id: 369723:STROP_RS18200
uniprot id: A4XAV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NucS endonuclease family.
messages: Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
messages: Cytoplasm

369723:STROP RS07165
gene id: 369723:STROP_RS07165
uniprot id: A4X4U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

369723:STROP RS20445
gene id: 369723:STROP_RS20445
uniprot id: A4XC30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS04480
gene id: 369723:STROP_RS04480
uniprot id: A4X3B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

369723:STROP RS08280
gene id: 369723:STROP_RS08280
uniprot id: A4X5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS19180
gene id: 369723:STROP_RS19180
uniprot id: A4XBE5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

369723:STROP RS12085
gene id: 369723:STROP_RS12085
uniprot id: A4X7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS02060
gene id: 369723:STROP_RS02060
uniprot id: A4X1Z4
names: Similarity
messages: Belongs to the UPF0234 family.

369723:STROP RS17705
gene id: 369723:STROP_RS17705
uniprot id: A4XAK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

369723:STROP RS01725
gene id: 369723:STROP_RS01725
uniprot id: A4X1S7
names: Cofactor
messages: Binds 1 FAD per subunit.

369723:STROP RS04310
gene id: 369723:STROP_RS04310
uniprot id: A4X378
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

369723:STROP RS11955
gene id: 369723:STROP_RS11955
uniprot id: A4X7H5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

369723:STROP RS04720
gene id: 369723:STROP_RS04720
uniprot id: A4X3F8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

369723:STROP RS19720
gene id: 369723:STROP_RS19720
uniprot id: A4XBP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

369723:STROP RS11150
gene id: 369723:STROP_RS11150
uniprot id: A4X718
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.

369723:STROP RS08325
gene id: 369723:STROP_RS08325
uniprot id: A4X5G6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

369723:STROP RS15460
gene id: 369723:STROP_RS15460
uniprot id: A4X9F8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

369723:STROP RS06600
gene id: 369723:STROP_RS06600
uniprot id: A4X4H8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

369723:STROP RS02500
gene id: 369723:STROP_RS02500
uniprot id: A4X280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

369723:STROP RS01090
gene id: 369723:STROP_RS01090
uniprot id: A4X1E8
names: Similarity
messages: Belongs to the DnaX/STICHEL family.

369723:STROP RS04355
gene id: 369723:STROP_RS04355
uniprot id: A4X386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

369723:STROP RS10640
gene id: 369723:STROP_RS10640
uniprot id: A4X6R5
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

369723:STROP RS16395
gene id: 369723:STROP_RS16395
uniprot id: A4X9W7
names: Similarity
messages: Belongs to the FAD-binding monooxygenase family.
messages: Belongs to the FMO family.

369723:STROP RS21870
gene id: 369723:STROP_RS21870
uniprot id: A4XCV6
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

369723:STROP RS14640
gene id: 369723:STROP_RS14640
uniprot id: A4X909
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS10155
gene id: 369723:STROP_RS10155
uniprot id: A4X6G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

369723:STROP RS15050
gene id: 369723:STROP_RS15050
uniprot id: A4X981
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurD2 subfamily.
messages: Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
messages: Cytoplasm

369723:STROP RS19610
gene id: 369723:STROP_RS19610
uniprot id: A4XBM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

369723:STROP RS06155
gene id: 369723:STROP_RS06155
uniprot id: A4X492
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

369723:STROP RS00390
gene id: 369723:STROP_RS00390
uniprot id: A4X112
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

369723:STROP RS12765
gene id: 369723:STROP_RS12765
uniprot id: A4X7Y1
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS18970
gene id: 369723:STROP_RS18970
uniprot id: A4XBA5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

369723:STROP RS06455
gene id: 369723:STROP_RS06455
uniprot id: A4X4E9
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

369723:STROP RS16055
gene id: 369723:STROP_RS16055
uniprot id: A4XDM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

369723:STROP RS02125
gene id: 369723:STROP_RS02125
uniprot id: A4X205
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

369723:STROP RS16725
gene id: 369723:STROP_RS16725
uniprot id: A4XA31
names: Similarity
messages: Belongs to the peptidase S66 family.

369723:STROP RS20475
gene id: 369723:STROP_RS20475
uniprot id: A4XC36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS23185
gene id: 369723:STROP_RS23185
uniprot id: A4XDK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

369723:STROP RS11760
gene id: 369723:STROP_RS11760
uniprot id: A4X7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

369723:STROP RS09295
gene id: 369723:STROP_RS09295
uniprot id: A4X607
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

369723:STROP RS23015
gene id: 369723:STROP_RS23015
uniprot id: A4XDH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

369723:STROP RS05195
gene id: 369723:STROP_RS05195
uniprot id: A4X3Q0
names: Disruption Phenotype
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.
messages: Cells lacking this gene are not able to produce salinosporamide A (SalA), however they produce salinosporamide B.
messages: Homotrimer.
messages: Involved in the biosynthesis of the proteosome inhibitor salinosporamide A (SalA). Catalyzes the halogenation of S-adenosyl-L-methionine (SAM) with chloride to generate 5'-chloro-5'-deoxyadenosine (5'-CIDA) and L-methionine. It can also use bromide and iodide, producing halogenated 5'-deoxyadenosine (5'-XDA) and L-methionine, however no halogenase activity is detected in the presence of fluoride.

369723:STROP RS04000
gene id: 369723:STROP_RS04000
uniprot id: A4X316
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

369723:STROP RS17205
gene id: 369723:STROP_RS17205
uniprot id: A4XAB1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

369723:STROP RS09420
gene id: 369723:STROP_RS09420
uniprot id: A4X632
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

369723:STROP RS07805
gene id: 369723:STROP_RS07805
uniprot id: A4X568
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

369723:STROP RS00530
gene id: 369723:STROP_RS00530
uniprot id: A4X142
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

369723:STROP RS06930
gene id: 369723:STROP_RS06930
uniprot id: A4X4P6
names: Similarity
messages: Belongs to the ribF family.

369723:STROP RS18140
gene id: 369723:STROP_RS18140
uniprot id: A4XAU0
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

369723:STROP RS11980
gene id: 369723:STROP_RS11980
uniprot id: A4X7I0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

369723:STROP RS09105
gene id: 369723:STROP_RS09105
uniprot id: A4X5W9
names: Similarity
messages: Belongs to the CdaR family.

369723:STROP RS08265
gene id: 369723:STROP_RS08265
uniprot id: A4X5F4
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

369723:STROP RS12810
gene id: 369723:STROP_RS12810
uniprot id: A4X7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

369723:STROP RS14820
gene id: 369723:STROP_RS14820
uniprot id: A4X939
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

369723:STROP RS10890
gene id: 369723:STROP_RS10890
uniprot id: A4X6W5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

369723:STROP RS18930
gene id: 369723:STROP_RS18930
uniprot id: A4XB97
names: Similarity
messages: Belongs to the peptidase U62 family.

369723:STROP RS02420
gene id: 369723:STROP_RS02420
uniprot id: A4X264
names: Similarity
messages: Belongs to the WXG100 family.

369723:STROP RS20460
gene id: 369723:STROP_RS20460
uniprot id: A4XC33
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

369723:STROP RS15375
gene id: 369723:STROP_RS15375
uniprot id: A4X9E1
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19085
gene id: 369723:STROP_RS19085
uniprot id: A4XBC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

369723:STROP RS09525
gene id: 369723:STROP_RS09525
uniprot id: A4X653
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

369723:STROP RS06225
gene id: 369723:STROP_RS06225
uniprot id: A4X4A6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

369723:STROP RS16360
gene id: 369723:STROP_RS16360
uniprot id: A4X9W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

369723:STROP RS15995
gene id: 369723:STROP_RS15995
uniprot id: A4X9Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

369723:STROP RS20025
gene id: 369723:STROP_RS20025
uniprot id: A4XBV1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

369723:STROP RS06925
gene id: 369723:STROP_RS06925
uniprot id: A4X4P5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

369723:STROP RS03320
gene id: 369723:STROP_RS03320
uniprot id: A4X2N3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS11560
gene id: 369723:STROP_RS11560
uniprot id: A4X798
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

369723:STROP RS00760
gene id: 369723:STROP_RS00760
uniprot id: A4X187
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

369723:STROP RS14965
gene id: 369723:STROP_RS14965
uniprot id: A4X0T3
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19695
gene id: 369723:STROP_RS19695
uniprot id: A4XBN8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

369723:STROP RS21960
gene id: 369723:STROP_RS21960
uniprot id: A4XCX4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

369723:STROP RS09955
gene id: 369723:STROP_RS09955
uniprot id: A4X6C9
names: Similarity
messages: Belongs to the WrbA family.

369723:STROP RS12125
gene id: 369723:STROP_RS12125
uniprot id: A4X7K6
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS04965
gene id: 369723:STROP_RS04965
uniprot id: A4X3K6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

369723:STROP RS12005
gene id: 369723:STROP_RS12005
uniprot id: A4X7I5
names: Similarity
messages: Belongs to the universal stress protein A family.

369723:STROP RS02175
gene id: 369723:STROP_RS02175
uniprot id: A4X215
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

369723:STROP RS08250
gene id: 369723:STROP_RS08250
uniprot id: A4X5F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS07135
gene id: 369723:STROP_RS07135
uniprot id: A4X4T7
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS04815
gene id: 369723:STROP_RS04815
uniprot id: A4X3H7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS19220
gene id: 369723:STROP_RS19220
uniprot id: A4XBF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS16670
gene id: 369723:STROP_RS16670
uniprot id: A4XA20
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

369723:STROP RS21210
gene id: 369723:STROP_RS21210
uniprot id: A4XCH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

369723:STROP RS06655
gene id: 369723:STROP_RS06655
uniprot id: A4X4I9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

369723:STROP RS07715
gene id: 369723:STROP_RS07715
uniprot id: A4X550
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

369723:STROP RS19985
gene id: 369723:STROP_RS19985
uniprot id: A4XBU3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

369723:STROP RS07295
gene id: 369723:STROP_RS07295
uniprot id: A4X4W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

369723:STROP RS08780
gene id: 369723:STROP_RS08780
uniprot id: A4X5Q5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

369723:STROP RS06850
gene id: 369723:STROP_RS06850
uniprot id: A4X4M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

369723:STROP RS04170
gene id: 369723:STROP_RS04170
uniprot id: A4X350
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS23035
gene id: 369723:STROP_RS23035
uniprot id: A4XDH5
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

369723:STROP RS15965
gene id: 369723:STROP_RS15965
uniprot id: A4X9P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

369723:STROP RS19280
gene id: 369723:STROP_RS19280
uniprot id: A4XBG4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

369723:STROP RS00775
gene id: 369723:STROP_RS00775
uniprot id: A4X189
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

369723:STROP RS05175
gene id: 369723:STROP_RS05175
uniprot id: A4X3P6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS19465
gene id: 369723:STROP_RS19465
uniprot id: A4XBJ2
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

369723:STROP RS18145
gene id: 369723:STROP_RS18145
uniprot id: A4XAU1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

369723:STROP RS12685
gene id: 369723:STROP_RS12685
uniprot id: A4X7W5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

369723:STROP RS12100
gene id: 369723:STROP_RS12100
uniprot id: A4X7K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS04975
gene id: 369723:STROP_RS04975
uniprot id: A4X3K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

369723:STROP RS19100
gene id: 369723:STROP_RS19100
uniprot id: A4XBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS15700
gene id: 369723:STROP_RS15700
uniprot id: A4X9J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

369723:STROP RS06500
gene id: 369723:STROP_RS06500
uniprot id: A4X4F8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

369723:STROP RS10985
gene id: 369723:STROP_RS10985
uniprot id: A4X6Y5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS20585
gene id: 369723:STROP_RS20585
uniprot id: A4XC58
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

369723:STROP RS22615
gene id: 369723:STROP_RS22615
uniprot id: A4XDA0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS05645
gene id: 369723:STROP_RS05645
uniprot id: A4X3Y9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19605
gene id: 369723:STROP_RS19605
uniprot id: A4XBM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

369723:STROP RS15805
gene id: 369723:STROP_RS15805
uniprot id: A4X9L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS19660
gene id: 369723:STROP_RS19660
uniprot id: A4XBN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

369723:STROP RS20450
gene id: 369723:STROP_RS20450
uniprot id: A4XC31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

369723:STROP RS19390
gene id: 369723:STROP_RS19390
uniprot id: A4XBH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

369723:STROP RS11175
gene id: 369723:STROP_RS11175
uniprot id: A4X723
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

369723:STROP RS19385
gene id: 369723:STROP_RS19385
uniprot id: A4XBH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

369723:STROP RS22660
gene id: 369723:STROP_RS22660
uniprot id: A4XDA9
names: Cofactor
messages: Binds 1 zinc ion per subunit.

369723:STROP RS17580
gene id: 369723:STROP_RS17580
uniprot id: A4XAI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

369723:STROP RS16060
gene id: 369723:STROP_RS16060
uniprot id: A4X9R0
names: Similarity
messages: Belongs to the YggT family.

369723:STROP RS04655
gene id: 369723:STROP_RS04655
uniprot id: A4X3E5
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

369723:STROP RS02180
gene id: 369723:STROP_RS02180
uniprot id: A4X216
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS07345
gene id: 369723:STROP_RS07345
uniprot id: A4X4X7
names: Similarity
messages: Belongs to the histone deacetylase family.

369723:STROP RS06350
gene id: 369723:STROP_RS06350
uniprot id: A4X4C8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

369723:STROP RS21665
gene id: 369723:STROP_RS21665
uniprot id: A4XCR7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

369723:STROP RS06700
gene id: 369723:STROP_RS06700
uniprot id: A4X4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

369723:STROP RS19795
gene id: 369723:STROP_RS19795
uniprot id: A4XBQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

369723:STROP RS00675
gene id: 369723:STROP_RS00675
uniprot id: A4X170
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

369723:STROP RS08580
gene id: 369723:STROP_RS08580
uniprot id: A4X5L5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

369723:STROP RS13985
gene id: 369723:STROP_RS13985
uniprot id: A4X8M7
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS04175
gene id: 369723:STROP_RS04175
uniprot id: A4X351
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

369723:STROP RS09310
gene id: 369723:STROP_RS09310
uniprot id: A4X610
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

369723:STROP RS09515
gene id: 369723:STROP_RS09515
uniprot id: A4X651
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

369723:STROP RS00570
gene id: 369723:STROP_RS00570
uniprot id: A4X150
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

369723:STROP RS10690
gene id: 369723:STROP_RS10690
uniprot id: A4X6S5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

369723:STROP RS12000
gene id: 369723:STROP_RS12000
uniprot id: A4X7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

369723:STROP RS04890
gene id: 369723:STROP_RS04890
uniprot id: A4X3J1
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

369723:STROP RS13035
gene id: 369723:STROP_RS13035
uniprot id: A4X834
names: Similarity
messages: Belongs to the DyP-type peroxidase family.

369723:STROP RS17285
gene id: 369723:STROP_RS17285
uniprot id: A4XAC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

369723:STROP RS20855
gene id: 369723:STROP_RS20855
uniprot id: A4XCA6
names: Similarity
messages: Belongs to the transposase 7 family.

369723:STROP RS17870
gene id: 369723:STROP_RS17870
uniprot id: A4XAN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

369723:STROP RS01160
gene id: 369723:STROP_RS01160
uniprot id: A4X1G2
names: Subunit
messages: Homodimer.

369723:STROP RS01795
gene id: 369723:STROP_RS01795
uniprot id: A4X1U1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

369723:STROP RS19735
gene id: 369723:STROP_RS19735
uniprot id: A4XBP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

369723:STROP RS21835
gene id: 369723:STROP_RS21835
uniprot id: A4XCV0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS06220
gene id: 369723:STROP_RS06220
uniprot id: A4X4A5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

369723:STROP RS20315
gene id: 369723:STROP_RS20315
uniprot id: A4XC03
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

369723:STROP RS05650
gene id: 369723:STROP_RS05650
uniprot id: A4X3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

369723:STROP RS01155
gene id: 369723:STROP_RS01155
uniprot id: A4X1G1
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

369723:STROP RS04715
gene id: 369723:STROP_RS04715
uniprot id: A4X3F7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS19415
gene id: 369723:STROP_RS19415
uniprot id: A4XBI3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS16130
gene id: 369723:STROP_RS16130
uniprot id: A4X9S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

369723:STROP RS10410
gene id: 369723:STROP_RS10410
uniprot id: A4X6L9
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19200
gene id: 369723:STROP_RS19200
uniprot id: A4XBE9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

369723:STROP RS06960
gene id: 369723:STROP_RS06960
uniprot id: A4X4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

369723:STROP RS12395
gene id: 369723:STROP_RS12395
uniprot id: A4X7Q9
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

369723:STROP RS07845
gene id: 369723:STROP_RS07845
uniprot id: A4X576
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

369723:STROP RS16605
gene id: 369723:STROP_RS16605
uniprot id: A4XA08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

369723:STROP RS10050
gene id: 369723:STROP_RS10050
uniprot id: A4X6E6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

369723:STROP RS03920
gene id: 369723:STROP_RS03920
uniprot id: A4X301
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS12895
gene id: 369723:STROP_RS12895
uniprot id: A4X807
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

369723:STROP RS06675
gene id: 369723:STROP_RS06675
uniprot id: A4X4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

369723:STROP RS16230
gene id: 369723:STROP_RS16230
uniprot id: A4X9U3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

369723:STROP RS00040
gene id: 369723:STROP_RS00040
uniprot id: A4X0U4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

369723:STROP RS13865
gene id: 369723:STROP_RS13865
uniprot id: A4X8K2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

369723:STROP RS18690
gene id: 369723:STROP_RS18690
uniprot id: A4XB52
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

369723:STROP RS03755
gene id: 369723:STROP_RS03755
uniprot id: A4X2X0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

369723:STROP RS19980
gene id: 369723:STROP_RS19980
uniprot id: A4XBU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

369723:STROP RS13425
gene id: 369723:STROP_RS13425
uniprot id: A4X8B3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

369723:STROP RS00645
gene id: 369723:STROP_RS00645
uniprot id: A4X165
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

369723:STROP RS08080
gene id: 369723:STROP_RS08080
uniprot id: A4X5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SsgA family.
messages: Cell septum
messages: Interacts with SsgA. Interacts with FtsZ (via N-terminus).
messages: Involved in sporulation-specific cell division (PubMed:19567872). Required for early stages of sporulation. Important in the process of growth cessation prior to sporulation-specific cell division. Recruits cell division protein FtsZ to the future septum sites and tethers the contractile ring structure (Z ring) to the cytoplasmic membrane during sporulation. Stimulates polymerization and filament length of FtsZ in vitro (By similarity).

369723:STROP RS10575
gene id: 369723:STROP_RS10575
uniprot id: A4X6Q2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

369723:STROP RS05300
gene id: 369723:STROP_RS05300
uniprot id: A4X3Q6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

369723:STROP RS14335
gene id: 369723:STROP_RS14335
uniprot id: A4X8U8
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

369723:STROP RS04115
gene id: 369723:STROP_RS04115
uniprot id: A4X339
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

369723:STROP RS11085
gene id: 369723:STROP_RS11085
uniprot id: A4X705
names: Similarity
messages: Belongs to the glutamine synthetase family.

369723:STROP RS23170
gene id: 369723:STROP_RS23170
uniprot id: A4XDK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

369723:STROP RS02015
gene id: 369723:STROP_RS02015
uniprot id: A4X1Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS04650
gene id: 369723:STROP_RS04650
uniprot id: A4X3E4
names: Similarity
messages: Belongs to the asparagine synthetase family.

369723:STROP RS02150
gene id: 369723:STROP_RS02150
uniprot id: A4X210
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS13060
gene id: 369723:STROP_RS13060
uniprot id: A4X839
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

369723:STROP RS07975
gene id: 369723:STROP_RS07975
uniprot id: A4X596
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

369723:STROP RS15930
gene id: 369723:STROP_RS15930
uniprot id: A4X9P0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS16100
gene id: 369723:STROP_RS16100
uniprot id: A4X9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

369723:STROP RS18855
gene id: 369723:STROP_RS18855
uniprot id: A4XB82
names: Similarity
messages: Belongs to the LOG family.

369723:STROP RS00885
gene id: 369723:STROP_RS00885
uniprot id: A4X1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

369723:STROP RS13160
gene id: 369723:STROP_RS13160
uniprot id: A4X859
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS18150
gene id: 369723:STROP_RS18150
uniprot id: A4XAU2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

369723:STROP RS06855
gene id: 369723:STROP_RS06855
uniprot id: A4X4N0
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS01665
gene id: 369723:STROP_RS01665
uniprot id: A4X1R5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS04435
gene id: 369723:STROP_RS04435
uniprot id: A4X3A2
names: Similarity
messages: Belongs to the FBPase class 2 family.

369723:STROP RS25420
gene id: 369723:STROP_RS25420
uniprot id: A4XDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

369723:STROP RS19635
gene id: 369723:STROP_RS19635
uniprot id: A4XBM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

369723:STROP RS05255
gene id: 369723:STROP_RS05255
uniprot id: A4X3R3
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

369723:STROP RS09350
gene id: 369723:STROP_RS09350
uniprot id: A4X618
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS04990
gene id: 369723:STROP_RS04990
uniprot id: A4X3L1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

369723:STROP RS01275
gene id: 369723:STROP_RS01275
uniprot id: A4X1I5
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12305
gene id: 369723:STROP_RS12305
uniprot id: A4X7P3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

369723:STROP RS02040
gene id: 369723:STROP_RS02040
uniprot id: A4X1Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

369723:STROP RS16105
gene id: 369723:STROP_RS16105
uniprot id: A4X9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

369723:STROP RS22755
gene id: 369723:STROP_RS22755
uniprot id: A4XDC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

369723:STROP RS10685
gene id: 369723:STROP_RS10685
uniprot id: A4X6S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

369723:STROP RS00890
gene id: 369723:STROP_RS00890
uniprot id: A4X1B2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

369723:STROP RS21755
gene id: 369723:STROP_RS21755
uniprot id: A4XCT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

369723:STROP RS04415
gene id: 369723:STROP_RS04415
uniprot id: A4X398
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

369723:STROP RS19815
gene id: 369723:STROP_RS19815
uniprot id: A4XBR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

369723:STROP RS00600
gene id: 369723:STROP_RS00600
uniprot id: A4X156
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

369723:STROP RS13705
gene id: 369723:STROP_RS13705
uniprot id: A4X8H1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

369723:STROP RS09430
gene id: 369723:STROP_RS09430
uniprot id: A4X634
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS09415
gene id: 369723:STROP_RS09415
uniprot id: A4X631
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

369723:STROP RS02115
gene id: 369723:STROP_RS02115
uniprot id: A4X203
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS08115
gene id: 369723:STROP_RS08115
uniprot id: A4X5C2
names: Subunit
messages: Homodimer.

369723:STROP RS06935
gene id: 369723:STROP_RS06935
uniprot id: A4X4P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

369723:STROP RS11430
gene id: 369723:STROP_RS11430
uniprot id: A4X772
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS20975
gene id: 369723:STROP_RS20975
uniprot id: A4XCC9
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

369723:STROP RS09535
gene id: 369723:STROP_RS09535
uniprot id: A4X655
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

369723:STROP RS03725
gene id: 369723:STROP_RS03725
uniprot id: A4X2W5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

369723:STROP RS18555
gene id: 369723:STROP_RS18555
uniprot id: A4XB24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

369723:STROP RS17740
gene id: 369723:STROP_RS17740
uniprot id: A4XAL1
names: Function
names: Similarity
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

369723:STROP RS00105
gene id: 369723:STROP_RS00105
uniprot id: A4X0V6
names: Similarity
messages: Belongs to the SufE family.

369723:STROP RS13530
gene id: 369723:STROP_RS13530
uniprot id: A4X8D4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS18365
gene id: 369723:STROP_RS18365
uniprot id: A4XAY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS13095
gene id: 369723:STROP_RS13095
uniprot id: A4X846
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS05570
gene id: 369723:STROP_RS05570
uniprot id: A4X3X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

369723:STROP RS03945
gene id: 369723:STROP_RS03945
uniprot id: A4X306
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Belongs to the precorrin methyltransferase family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

369723:STROP RS14635
gene id: 369723:STROP_RS14635
uniprot id: A4X908
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS22045
gene id: 369723:STROP_RS22045
uniprot id: A4XCZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

369723:STROP RS06145
gene id: 369723:STROP_RS06145
uniprot id: A4X490
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

369723:STROP RS08505
gene id: 369723:STROP_RS08505
uniprot id: A4X5K0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

369723:STROP RS22940
gene id: 369723:STROP_RS22940
uniprot id: A4XDF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

369723:STROP RS09680
gene id: 369723:STROP_RS09680
uniprot id: A4X679
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS09330
gene id: 369723:STROP_RS09330
uniprot id: A4X614
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

369723:STROP RS11280
gene id: 369723:STROP_RS11280
uniprot id: A4X743
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

369723:STROP RS04200
gene id: 369723:STROP_RS04200
uniprot id: A4X356
names: Similarity
messages: Belongs to the UPRTase family.

369723:STROP RS19430
gene id: 369723:STROP_RS19430
uniprot id: A4XBI6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

369723:STROP RS18495
gene id: 369723:STROP_RS18495
uniprot id: A4XB12
names: Similarity
messages: Belongs to the CutA family.

369723:STROP RS00785
gene id: 369723:STROP_RS00785
uniprot id: A4X191
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

369723:STROP RS09140
gene id: 369723:STROP_RS09140
uniprot id: A4X5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

369723:STROP RS19730
gene id: 369723:STROP_RS19730
uniprot id: A4XBP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

369723:STROP RS15285
gene id: 369723:STROP_RS15285
uniprot id: A4X9C3
names: Similarity
messages: Belongs to the peptidase M20A family.

369723:STROP RS09170
gene id: 369723:STROP_RS09170
uniprot id: A4X5Y1
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

369723:STROP RS16150
gene id: 369723:STROP_RS16150
uniprot id: A4X9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

369723:STROP RS12835
gene id: 369723:STROP_RS12835
uniprot id: A4X7Z5
names: Similarity
messages: Belongs to the group II decarboxylase family.

369723:STROP RS13660
gene id: 369723:STROP_RS13660
uniprot id: A4X8G2
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19425
gene id: 369723:STROP_RS19425
uniprot id: A4XBI5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

369723:STROP RS16560
gene id: 369723:STROP_RS16560
uniprot id: A4XA00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

369723:STROP RS11185
gene id: 369723:STROP_RS11185
uniprot id: A4X725
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS20430
gene id: 369723:STROP_RS20430
uniprot id: A4XC27
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS12580
gene id: 369723:STROP_RS12580
uniprot id: A4X7U5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

369723:STROP RS21610
gene id: 369723:STROP_RS21610
uniprot id: A4XCQ6
names: Subcellular Location Annotation
messages: Mitochondrion

369723:STROP RS00085
gene id: 369723:STROP_RS00085
uniprot id: A4X0V2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

369723:STROP RS09340
gene id: 369723:STROP_RS09340
uniprot id: A4X616
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

369723:STROP RS06605
gene id: 369723:STROP_RS06605
uniprot id: A4X4H9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

369723:STROP RS17995
gene id: 369723:STROP_RS17995
uniprot id: A4XAR1
names: Similarity
messages: Belongs to the peptidase C40 family.

369723:STROP RS09220
gene id: 369723:STROP_RS09220
uniprot id: A4X5Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

369723:STROP RS18440
gene id: 369723:STROP_RS18440
uniprot id: A4XB01
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

369723:STROP RS15180
gene id: 369723:STROP_RS15180
uniprot id: A4X9A8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS07175
gene id: 369723:STROP_RS07175
uniprot id: A4X4U6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

369723:STROP RS01540
gene id: 369723:STROP_RS01540
uniprot id: A4X1P0
names: Similarity
messages: Belongs to the peptidase S8 family.

369723:STROP RS14805
gene id: 369723:STROP_RS14805
uniprot id: A4X936
names: Similarity
messages: Belongs to the peptidase S1 family.

369723:STROP RS05235
gene id: 369723:STROP_RS05235
uniprot id: A4X3Q9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

369723:STROP RS23140
gene id: 369723:STROP_RS23140
uniprot id: A4XDJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

369723:STROP RS21295
gene id: 369723:STROP_RS21295
uniprot id: A4XCJ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS23115
gene id: 369723:STROP_RS23115
uniprot id: A4XDJ1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

369723:STROP RS08630
gene id: 369723:STROP_RS08630
uniprot id: A4X5M5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

369723:STROP RS04180
gene id: 369723:STROP_RS04180
uniprot id: A4X352
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

369723:STROP RS18785
gene id: 369723:STROP_RS18785
uniprot id: A4XB69
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

369723:STROP RS04930
gene id: 369723:STROP_RS04930
uniprot id: A4X3J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

369723:STROP RS19040
gene id: 369723:STROP_RS19040
uniprot id: A4XBB8
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS03765
gene id: 369723:STROP_RS03765
uniprot id: A4X2X2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

369723:STROP RS22455
gene id: 369723:STROP_RS22455
uniprot id: A4XD68
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS17805
gene id: 369723:STROP_RS17805
uniprot id: A4XAM4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

369723:STROP RS04240
gene id: 369723:STROP_RS04240
uniprot id: A4X364
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

369723:STROP RS06370
gene id: 369723:STROP_RS06370
uniprot id: A4X4D2
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

369723:STROP RS09175
gene id: 369723:STROP_RS09175
uniprot id: A4X5Y2
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

369723:STROP RS00130
gene id: 369723:STROP_RS00130
uniprot id: A4X0W1
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

369723:STROP RS15030
gene id: 369723:STROP_RS15030
uniprot id: A4X978
names: Similarity
messages: Belongs to the asparaginase 1 family.

369723:STROP RS18350
gene id: 369723:STROP_RS18350
uniprot id: A4XAY2
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

369723:STROP RS11265
gene id: 369723:STROP_RS11265
uniprot id: A4X740
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

369723:STROP RS22235
gene id: 369723:STROP_RS22235
uniprot id: A4XD27
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS03715
gene id: 369723:STROP_RS03715
uniprot id: A4X2W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS00355
gene id: 369723:STROP_RS00355
uniprot id: A4X104
names: Similarity
messages: Belongs to the Nudix hydrolase family.

369723:STROP RS15935
gene id: 369723:STROP_RS15935
uniprot id: A4X9P1
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS19625
gene id: 369723:STROP_RS19625
uniprot id: A4XBM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

369723:STROP RS11780
gene id: 369723:STROP_RS11780
uniprot id: A4X7E1
names: Similarity
messages: Belongs to the thymidine kinase family.

369723:STROP RS15555
gene id: 369723:STROP_RS15555
uniprot id: A4X9G8
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

369723:STROP RS13180
gene id: 369723:STROP_RS13180
uniprot id: A4X863
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

369723:STROP RS19800
gene id: 369723:STROP_RS19800
uniprot id: A4XBQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

369723:STROP RS06075
gene id: 369723:STROP_RS06075
uniprot id: A4X476
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS22985
gene id: 369723:STROP_RS22985
uniprot id: A4XDG5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

369723:STROP RS02265
gene id: 369723:STROP_RS02265
uniprot id: A4X233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

369723:STROP RS06685
gene id: 369723:STROP_RS06685
uniprot id: A4X4J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

369723:STROP RS17745
gene id: 369723:STROP_RS17745
uniprot id: A4XAL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

369723:STROP RS11230
gene id: 369723:STROP_RS11230
uniprot id: A4X733
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS15910
gene id: 369723:STROP_RS15910
uniprot id: A4X9N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS09270
gene id: 369723:STROP_RS09270
uniprot id: A4X601
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

369723:STROP RS04290
gene id: 369723:STROP_RS04290
uniprot id: A4X374
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS06945
gene id: 369723:STROP_RS06945
uniprot id: A4X4P9
names: Similarity
messages: Belongs to the peptidase M16 family.

369723:STROP RS03890
gene id: 369723:STROP_RS03890
uniprot id: A4X2Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS06575
gene id: 369723:STROP_RS06575
uniprot id: A4X4H3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

369723:STROP RS17530
gene id: 369723:STROP_RS17530
uniprot id: A4XAH4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

369723:STROP RS00620
gene id: 369723:STROP_RS00620
uniprot id: A4X160
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS19300
gene id: 369723:STROP_RS19300
uniprot id: A4XBG8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

369723:STROP RS11335
gene id: 369723:STROP_RS11335
uniprot id: A4X753
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

369723:STROP RS02510
gene id: 369723:STROP_RS02510
uniprot id: A4X282
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

369723:STROP RS15200
gene id: 369723:STROP_RS15200
uniprot id: A4X9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

369723:STROP RS05960
gene id: 369723:STROP_RS05960
uniprot id: A4X454
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

369723:STROP RS00945
gene id: 369723:STROP_RS00945
uniprot id: A4X1C0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

369723:STROP RS15145
gene id: 369723:STROP_RS15145
uniprot id: A4X9A0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

369723:STROP RS01980
gene id: 369723:STROP_RS01980
uniprot id: A4X1X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

369723:STROP RS19650
gene id: 369723:STROP_RS19650
uniprot id: A4XBM9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

369723:STROP RS14850
gene id: 369723:STROP_RS14850
uniprot id: A4X945
names: Subcellular Location Annotation
messages: Membrane

369723:STROP RS07005
gene id: 369723:STROP_RS07005
uniprot id: A4X4R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

369723:STROP RS11290
gene id: 369723:STROP_RS11290
uniprot id: A4X745
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

369723:STROP RS04365
gene id: 369723:STROP_RS04365
uniprot id: A4X388
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

369723:STROP RS15060
gene id: 369723:STROP_RS15060
uniprot id: A4X983
names: Similarity
messages: Belongs to the CdaR family.

369723:STROP RS19435
gene id: 369723:STROP_RS19435
uniprot id: A4XBI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

369723:STROP RS18860
gene id: 369723:STROP_RS18860
uniprot id: A4XB83
names: Similarity
messages: Belongs to the LOG family.

369723:STROP RS01225
gene id: 369723:STROP_RS01225
uniprot id: A4X1H5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

369723:STROP RS18040
gene id: 369723:STROP_RS18040
uniprot id: A4XAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

369723:STROP RS06650
gene id: 369723:STROP_RS06650
uniprot id: A4X4I8
names: Similarity
messages: Belongs to the DprA/Smf family.

369723:STROP RS06735
gene id: 369723:STROP_RS06735
uniprot id: A4X4K7
names: Similarity
messages: Belongs to the cytochrome P450 family.

369723:STROP RS13085
gene id: 369723:STROP_RS13085
uniprot id: A4X844
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

369723:STROP RS20735
gene id: 369723:STROP_RS20735
uniprot id: A4XC87
names: Similarity
messages: Belongs to the UPF0098 family.

369723:STROP RS22075
gene id: 369723:STROP_RS22075
uniprot id: A4XCZ5
names: Similarity
messages: Belongs to the group II decarboxylase family.

369723:STROP RS16145
gene id: 369723:STROP_RS16145
uniprot id: A4X9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

369723:STROP RS21895
gene id: 369723:STROP_RS21895
uniprot id: A4XCW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

369723:STROP RS07015
gene id: 369723:STROP_RS07015
uniprot id: A4X4R3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

369723:STROP RS14890
gene id: 369723:STROP_RS14890
uniprot id: A4X953
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

369723:STROP RS06615
gene id: 369723:STROP_RS06615
uniprot id: A4X4I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

369723:STROP RS06355
gene id: 369723:STROP_RS06355
uniprot id: A4X4C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.