361183:AMC99 RS07170
gene id: 361183:AMC99_RS07170
uniprot id: A0A0M3TAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

361183:AMC99 RS05820
gene id: 361183:AMC99_RS05820
uniprot id: A0A0M3TA60
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

361183:AMC99 RS07475
gene id: 361183:AMC99_RS07475
uniprot id: A0A0M5KYL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

361183:AMC99 RS08230
gene id: 361183:AMC99_RS08230
uniprot id: A0A0M4MW93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

361183:AMC99 RS05410
gene id: 361183:AMC99_RS05410
uniprot id: A0A0M3TA44
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

361183:AMC99 RS12840
gene id: 361183:AMC99_RS12840
uniprot id: A0A0M4LWX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

361183:AMC99 RS04105
gene id: 361183:AMC99_RS04105
uniprot id: A0A0M5KYC1
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05900
gene id: 361183:AMC99_RS05900
uniprot id: A0A0M4MTB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

361183:AMC99 RS01490
gene id: 361183:AMC99_RS01490
uniprot id: A0A0M4MRJ9
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS04410
gene id: 361183:AMC99_RS04410
uniprot id: A0A0M4M738
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

361183:AMC99 RS03890
gene id: 361183:AMC99_RS03890
uniprot id: A0A0M4LTJ9
names: Similarity
messages: Belongs to the AlaDH/PNT family.

361183:AMC99 RS00715
gene id: 361183:AMC99_RS00715
uniprot id: A0A0M4MR89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS09270
gene id: 361183:AMC99_RS09270
uniprot id: A0A0M3TAQ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

361183:AMC99 RS03955
gene id: 361183:AMC99_RS03955
uniprot id: A0A0M4LTK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

361183:AMC99 RS04185
gene id: 361183:AMC99_RS04185
uniprot id: A0A0M4M6Y9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is located at the dimer interface.

361183:AMC99 RS08170
gene id: 361183:AMC99_RS08170
uniprot id: A0A0M4MW83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

361183:AMC99 RS04905
gene id: 361183:AMC99_RS04905
uniprot id: A0A0M4LUK3
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS04730
gene id: 361183:AMC99_RS04730
uniprot id: A0A0M5KYD8
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

361183:AMC99 RS02685
gene id: 361183:AMC99_RS02685
uniprot id: A0A0M5L4S0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

361183:AMC99 RS07090
gene id: 361183:AMC99_RS07090
uniprot id: A0A0M3TAH9
names: Similarity
messages: Belongs to the DEAD box helicase family.

361183:AMC99 RS11345
gene id: 361183:AMC99_RS11345
uniprot id: A0A0M4M9R5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

361183:AMC99 RS10075
gene id: 361183:AMC99_RS10075
uniprot id: A0A0M3TAN3
names: Function
messages: Multidrug efflux pump.

361183:AMC99 RS03275
gene id: 361183:AMC99_RS03275
uniprot id: A0A0M4LTC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

361183:AMC99 RS13495
gene id: 361183:AMC99_RS13495
uniprot id: A0A0M3TB73
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS02000
gene id: 361183:AMC99_RS02000
uniprot id: A0A0M4M685
names: Similarity
messages: Belongs to the Gfa family.

361183:AMC99 RS12800
gene id: 361183:AMC99_RS12800
uniprot id: A0A0M3TB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

361183:AMC99 RS00995
gene id: 361183:AMC99_RS00995
uniprot id: A0A0M4MEN3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

361183:AMC99 RS04475
gene id: 361183:AMC99_RS04475
uniprot id: A0A0M4M746
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

361183:AMC99 RS06145
gene id: 361183:AMC99_RS06145
uniprot id: A0A0M3TAC9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

361183:AMC99 RS02100
gene id: 361183:AMC99_RS02100
uniprot id: A0A0M4MF30
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

361183:AMC99 RS09635
gene id: 361183:AMC99_RS09635
uniprot id: A0A0M3TAK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS02880
gene id: 361183:AMC99_RS02880
uniprot id: A0A0M4M6F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS06790
gene id: 361183:AMC99_RS06790
uniprot id: A0A0M4LV92
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

361183:AMC99 RS02180
gene id: 361183:AMC99_RS02180
uniprot id: A0A0M4LTK3
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

361183:AMC99 RS06970
gene id: 361183:AMC99_RS06970
uniprot id: A0A0M4MTQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

361183:AMC99 RS12135
gene id: 361183:AMC99_RS12135
uniprot id: A0A0M3TAW0
names: Similarity
messages: Belongs to the HesB/IscA family.

361183:AMC99 RS09210
gene id: 361183:AMC99_RS09210
uniprot id: A0A0M4M8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

361183:AMC99 RS12385
gene id: 361183:AMC99_RS12385
uniprot id: A0A0M4MXU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

361183:AMC99 RS08235
gene id: 361183:AMC99_RS08235
uniprot id: A0A0M3TAL6
names: Similarity
messages: Belongs to the peptidase S8 family.

361183:AMC99 RS11865
gene id: 361183:AMC99_RS11865
uniprot id: A0A0M4MVI3
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS12865
gene id: 361183:AMC99_RS12865
uniprot id: A0A0M4LXG8
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

361183:AMC99 RS03590
gene id: 361183:AMC99_RS03590
uniprot id: A0A0M3T9W9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

361183:AMC99 RS09470
gene id: 361183:AMC99_RS09470
uniprot id: A0A0M4LVM7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS04950
gene id: 361183:AMC99_RS04950
uniprot id: A0A0M4MG77
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS01385
gene id: 361183:AMC99_RS01385
uniprot id: A0A0M4MTT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

361183:AMC99 RS07200
gene id: 361183:AMC99_RS07200
uniprot id: A0A0M4MH06
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

361183:AMC99 RS05155
gene id: 361183:AMC99_RS05155
uniprot id: A0A0M5L4Z4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

361183:AMC99 RS03875
gene id: 361183:AMC99_RS03875
uniprot id: A0A0M4MUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

361183:AMC99 RS09415
gene id: 361183:AMC99_RS09415
uniprot id: A0A0M3TAR2
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05370
gene id: 361183:AMC99_RS05370
uniprot id: A0A0M3TA42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

361183:AMC99 RS06825
gene id: 361183:AMC99_RS06825
uniprot id: A0A0M4LUP1
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

361183:AMC99 RS12685
gene id: 361183:AMC99_RS12685
uniprot id: A0A0M4MA79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

361183:AMC99 RS04855
gene id: 361183:AMC99_RS04855
uniprot id: A0A0M5L4Y5
names: Cofactor
messages: Can also use Mn(2+) ion.

361183:AMC99 RS03580
gene id: 361183:AMC99_RS03580
uniprot id: A0A0M4M389
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS01225
gene id: 361183:AMC99_RS01225
uniprot id: A0A0M3T9T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS09330
gene id: 361183:AMC99_RS09330
uniprot id: A0A0M4M8X8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

361183:AMC99 RS08525
gene id: 361183:AMC99_RS08525
uniprot id: A0A0M5KZN5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

361183:AMC99 RS06075
gene id: 361183:AMC99_RS06075
uniprot id: A0A0M3TA70
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

361183:AMC99 RS06720
gene id: 361183:AMC99_RS06720
uniprot id: A0A0M4MTM1
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

361183:AMC99 RS07175
gene id: 361183:AMC99_RS07175
uniprot id: A0A0M4MVW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

361183:AMC99 RS06065
gene id: 361183:AMC99_RS06065
uniprot id: A0A0M4M482
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS02215
gene id: 361183:AMC99_RS02215
uniprot id: A0A0M3T9X4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS10080
gene id: 361183:AMC99_RS10080
uniprot id: A0A0M4M5L0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

361183:AMC99 RS10370
gene id: 361183:AMC99_RS10370
uniprot id: A0A0M4MI79
names: Similarity
messages: Belongs to the peptidase M16 family.

361183:AMC99 RS10175
gene id: 361183:AMC99_RS10175
uniprot id: A0A0M3TAN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

361183:AMC99 RS02065
gene id: 361183:AMC99_RS02065
uniprot id: A0A0M3T9W8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS04810
gene id: 361183:AMC99_RS04810
uniprot id: A0A0M4M771
names: Similarity
messages: Belongs to the YkuD family.

361183:AMC99 RS06395
gene id: 361183:AMC99_RS06395
uniprot id: A0A0M5L0C7
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

361183:AMC99 RS03855
gene id: 361183:AMC99_RS03855
uniprot id: A0A0M3TA39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

361183:AMC99 RS04370
gene id: 361183:AMC99_RS04370
uniprot id: A0A0M3TA02
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

361183:AMC99 RS06365
gene id: 361183:AMC99_RS06365
uniprot id: A0A0M4M7T7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

361183:AMC99 RS08265
gene id: 361183:AMC99_RS08265
uniprot id: A0A0M4MU72
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS08290
gene id: 361183:AMC99_RS08290
uniprot id: A0A0M4M8J3
names: Similarity
messages: Belongs to the SufE family.

361183:AMC99 RS09545
gene id: 361183:AMC99_RS09545
uniprot id: A0A0M5L781
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

361183:AMC99 RS07915
gene id: 361183:AMC99_RS07915
uniprot id: A0A0M5KZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

361183:AMC99 RS05130
gene id: 361183:AMC99_RS05130
uniprot id: A0A0M3TA90
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

361183:AMC99 RS07220
gene id: 361183:AMC99_RS07220
uniprot id: A0A0M3TAB9
names: Similarity
messages: Belongs to the PhzF family.

361183:AMC99 RS03145
gene id: 361183:AMC99_RS03145
uniprot id: A0A0M4MFH1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

361183:AMC99 RS09225
gene id: 361183:AMC99_RS09225
uniprot id: A0A0M3TAQ4
names: Similarity
messages: Belongs to the peptidase M17 family.

361183:AMC99 RS04270
gene id: 361183:AMC99_RS04270
uniprot id: A0A0M3T9Z7
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

361183:AMC99 RS12035
gene id: 361183:AMC99_RS12035
uniprot id: A0A0M3TAV6
names: Function
names: Similarity
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: May be required for disulfide bond formation in some proteins.

361183:AMC99 RS05300
gene id: 361183:AMC99_RS05300
uniprot id: A0A0M4M7E3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

361183:AMC99 RS07155
gene id: 361183:AMC99_RS07155
uniprot id: A0A0M4LVD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

361183:AMC99 RS00780
gene id: 361183:AMC99_RS00780
uniprot id: A0A0M3T9K8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

361183:AMC99 RS13170
gene id: 361183:AMC99_RS13170
uniprot id: A0A0M4MVZ2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

361183:AMC99 RS06000
gene id: 361183:AMC99_RS06000
uniprot id: A0A0M4M7P1
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05815
gene id: 361183:AMC99_RS05815
uniprot id: A0A0M4LUA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

361183:AMC99 RS06470
gene id: 361183:AMC99_RS06470
uniprot id: A0A0M3TA87
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

361183:AMC99 RS13715
gene id: 361183:AMC99_RS13715
uniprot id: A0A0M3TB20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS05705
gene id: 361183:AMC99_RS05705
uniprot id: A0A0M5KYH0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

361183:AMC99 RS08100
gene id: 361183:AMC99_RS08100
uniprot id: A0A0M4M8G7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

361183:AMC99 RS09580
gene id: 361183:AMC99_RS09580
uniprot id: A0A0M4M914
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

361183:AMC99 RS08385
gene id: 361183:AMC99_RS08385
uniprot id: A0A0M4MU89
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS04430
gene id: 361183:AMC99_RS04430
uniprot id: A0A0M4M720
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

361183:AMC99 RS00470
gene id: 361183:AMC99_RS00470
uniprot id: A0A0M4M5Q1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

361183:AMC99 RS11540
gene id: 361183:AMC99_RS11540
uniprot id: A0A0M4LWF1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS07555
gene id: 361183:AMC99_RS07555
uniprot id: A0A0M4M4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

361183:AMC99 RS05880
gene id: 361183:AMC99_RS05880
uniprot id: A0A0M4LUB4
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

361183:AMC99 RS03285
gene id: 361183:AMC99_RS03285
uniprot id: A0A0M5L028
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

361183:AMC99 RS10410
gene id: 361183:AMC99_RS10410
uniprot id: A0A0M4MX24
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

361183:AMC99 RS01650
gene id: 361183:AMC99_RS01650
uniprot id: A0A0M4M5Y2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

361183:AMC99 RS05670
gene id: 361183:AMC99_RS05670
uniprot id: A0A0M4M7K4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS06110
gene id: 361183:AMC99_RS06110
uniprot id: A0A0M5L527
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

361183:AMC99 RS12435
gene id: 361183:AMC99_RS12435
uniprot id: A0A0M4MA48
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS03870
gene id: 361183:AMC99_RS03870
uniprot id: A0A0M5KZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

361183:AMC99 RS01655
gene id: 361183:AMC99_RS01655
uniprot id: A0A0M3T9P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

361183:AMC99 RS08660
gene id: 361183:AMC99_RS08660
uniprot id: A0A0M3TAN2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS11285
gene id: 361183:AMC99_RS11285
uniprot id: A0A0M4MXE9
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS02080
gene id: 361183:AMC99_RS02080
uniprot id: A0A0M4M643
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

361183:AMC99 RS12235
gene id: 361183:AMC99_RS12235
uniprot id: A0A0M4MVN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

361183:AMC99 RS05100
gene id: 361183:AMC99_RS05100
uniprot id: A0A0M4MV56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

361183:AMC99 RS08395
gene id: 361183:AMC99_RS08395
uniprot id: A0A0M4M8K6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

361183:AMC99 RS04135
gene id: 361183:AMC99_RS04135
uniprot id: A0A0M4MFV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

361183:AMC99 RS09720
gene id: 361183:AMC99_RS09720
uniprot id: A0A0M4LVR0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

361183:AMC99 RS13350
gene id: 361183:AMC99_RS13350
uniprot id: A0A0M4MJG2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

361183:AMC99 RS09235
gene id: 361183:AMC99_RS09235
uniprot id: A0A0M4M5A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

361183:AMC99 RS11045
gene id: 361183:AMC99_RS11045
uniprot id: A0A0M4MXB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

361183:AMC99 RS07965
gene id: 361183:AMC99_RS07965
uniprot id: A0A0M4LVN4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

361183:AMC99 RS05075
gene id: 361183:AMC99_RS05075
uniprot id: A0A0M4MSZ2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

361183:AMC99 RS09570
gene id: 361183:AMC99_RS09570
uniprot id: A0A0M5KYU2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

361183:AMC99 RS11905
gene id: 361183:AMC99_RS11905
uniprot id: A0A0M3TB21
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

361183:AMC99 RS12915
gene id: 361183:AMC99_RS12915
uniprot id: A0A0M4MVW6
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

361183:AMC99 RS13540
gene id: 361183:AMC99_RS13540
uniprot id: A0A0M4MW41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS04275
gene id: 361183:AMC99_RS04275
uniprot id: A0A0M4MSM4
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

361183:AMC99 RS11855
gene id: 361183:AMC99_RS11855
uniprot id: A0A0M3TB19
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

361183:AMC99 RS00830
gene id: 361183:AMC99_RS00830
uniprot id: A0A0M4MRA6
names: Similarity
messages: Belongs to the asparagine synthetase family.

361183:AMC99 RS01080
gene id: 361183:AMC99_RS01080
uniprot id: A0A0M5KYZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

361183:AMC99 RS12365
gene id: 361183:AMC99_RS12365
uniprot id: A0A0M4LXB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

361183:AMC99 RS12250
gene id: 361183:AMC99_RS12250
uniprot id: A0A0M3TB34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

361183:AMC99 RS06625
gene id: 361183:AMC99_RS06625
uniprot id: A0A0M4M4F2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS06080
gene id: 361183:AMC99_RS06080
uniprot id: A0A0M4MGM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS12440
gene id: 361183:AMC99_RS12440
uniprot id: A0A0M5KZ35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

361183:AMC99 RS13255
gene id: 361183:AMC99_RS13255
uniprot id: A0A0M5L5S2
names: Subcellular Location Annotation
messages: Cytoplasm

361183:AMC99 RS12690
gene id: 361183:AMC99_RS12690
uniprot id: A0A0M5KZ46
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

361183:AMC99 RS10580
gene id: 361183:AMC99_RS10580
uniprot id: A0A0M4LWL0
names: Similarity
messages: Belongs to the FrmR/RcnR family.

361183:AMC99 RS06595
gene id: 361183:AMC99_RS06595
uniprot id: A0A0M4LV72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

361183:AMC99 RS06410
gene id: 361183:AMC99_RS06410
uniprot id: A0A0M4M7W7
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

361183:AMC99 RS07455
gene id: 361183:AMC99_RS07455
uniprot id: A0A0M4MTW0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

361183:AMC99 RS07250
gene id: 361183:AMC99_RS07250
uniprot id: A0A0M4M4M6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

361183:AMC99 RS11805
gene id: 361183:AMC99_RS11805
uniprot id: A0A0M4LX37
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS10700
gene id: 361183:AMC99_RS10700
uniprot id: A0A0M3TAQ7
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05995
gene id: 361183:AMC99_RS05995
uniprot id: A0A0M3TAC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

361183:AMC99 RS13075
gene id: 361183:AMC99_RS13075
uniprot id: A0A0M4MAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

361183:AMC99 RS01495
gene id: 361183:AMC99_RS01495
uniprot id: A0A0M4LTC2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

361183:AMC99 RS07725
gene id: 361183:AMC99_RS07725
uniprot id: A0A0M5KYN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

361183:AMC99 RS05845
gene id: 361183:AMC99_RS05845
uniprot id: A0A0M4LUY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

361183:AMC99 RS05065
gene id: 361183:AMC99_RS05065
uniprot id: A0A0M4MG93
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS01005
gene id: 361183:AMC99_RS01005
uniprot id: A0A0M4MRD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 25 family.

361183:AMC99 RS06005
gene id: 361183:AMC99_RS06005
uniprot id: A0A0M4M476
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS12780
gene id: 361183:AMC99_RS12780
uniprot id: A0A0M3TAY5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

361183:AMC99 RS02095
gene id: 361183:AMC99_RS02095
uniprot id: A0A0M3T9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

361183:AMC99 RS09730
gene id: 361183:AMC99_RS09730
uniprot id: A0A0M5KYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

361183:AMC99 RS04540
gene id: 361183:AMC99_RS04540
uniprot id: A0A0M5L4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

361183:AMC99 RS08570
gene id: 361183:AMC99_RS08570
uniprot id: A0A0M4LVW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

361183:AMC99 RS10875
gene id: 361183:AMC99_RS10875
uniprot id: A0A0M4LW61
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily.

361183:AMC99 RS06370
gene id: 361183:AMC99_RS06370
uniprot id: A0A0M3TA83
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS06335
gene id: 361183:AMC99_RS06335
uniprot id: A0A0M4MTH5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

361183:AMC99 RS07485
gene id: 361183:AMC99_RS07485
uniprot id: A0A0M3TAJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

361183:AMC99 RS02740
gene id: 361183:AMC99_RS02740
uniprot id: A0A0M4M6H8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS05135
gene id: 361183:AMC99_RS05135
uniprot id: A0A0M5L088
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

361183:AMC99 RS05835
gene id: 361183:AMC99_RS05835
uniprot id: A0A0M4MTB0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

361183:AMC99 RS05445
gene id: 361183:AMC99_RS05445
uniprot id: A0A0M5L098
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS06095
gene id: 361183:AMC99_RS06095
uniprot id: A0A0M3TAC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

361183:AMC99 RS05205
gene id: 361183:AMC99_RS05205
uniprot id: A0A0M4LUP4
names: Similarity
messages: Belongs to the LacAB/RpiB family.

361183:AMC99 RS06090
gene id: 361183:AMC99_RS06090
uniprot id: A0A0M4MTE3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS09450
gene id: 361183:AMC99_RS09450
uniprot id: A0A0M5KZS1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

361183:AMC99 RS06240
gene id: 361183:AMC99_RS06240
uniprot id: A0A0M4MVK6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS09775
gene id: 361183:AMC99_RS09775
uniprot id: A0A0M4LVR8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS04250
gene id: 361183:AMC99_RS04250
uniprot id: A0A0M4M3G6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

361183:AMC99 RS01660
gene id: 361183:AMC99_RS01660
uniprot id: A0A0M4M2L8
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

361183:AMC99 RS07060
gene id: 361183:AMC99_RS07060
uniprot id: A0A0M4M830
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS00010
gene id: 361183:AMC99_RS00010
uniprot id: A0A0M5L6A2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

361183:AMC99 RS10400
gene id: 361183:AMC99_RS10400
uniprot id: A0A0M5KZV2
names: Similarity
messages: Belongs to the UPF0174 family.

361183:AMC99 RS09190
gene id: 361183:AMC99_RS09190
uniprot id: A0A0M5L0L9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

361183:AMC99 RS06770
gene id: 361183:AMC99_RS06770
uniprot id: A0A0M4MGV7
names: Similarity
messages: Belongs to the peptidase S66 family.

361183:AMC99 RS12655
gene id: 361183:AMC99_RS12655
uniprot id: A0A0M4LWV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

361183:AMC99 RS09740
gene id: 361183:AMC99_RS09740
uniprot id: A0A0M4MUQ5
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

361183:AMC99 RS01405
gene id: 361183:AMC99_RS01405
uniprot id: A0A0M4LSP3
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS13920
gene id: 361183:AMC99_RS13920
uniprot id: A0A0M4LT41
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS07050
gene id: 361183:AMC99_RS07050
uniprot id: A0A0M5L560
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

361183:AMC99 RS05800
gene id: 361183:AMC99_RS05800
uniprot id: A0A0M4MVF8
names: Caution
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Belongs to the IspF family.
messages: Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
messages: In the C-terminal section; belongs to the IspF family.
messages: In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS02300
gene id: 361183:AMC99_RS02300
uniprot id: A0A0M4MRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS05750
gene id: 361183:AMC99_RS05750
uniprot id: A0A0M4M7L2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

361183:AMC99 RS00145
gene id: 361183:AMC99_RS00145
uniprot id: A0A0M4MR21
names: Similarity
messages: Belongs to the SBNO family.

361183:AMC99 RS02745
gene id: 361183:AMC99_RS02745
uniprot id: A0A0M5KY73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

361183:AMC99 RS05315
gene id: 361183:AMC99_RS05315
uniprot id: A0A0M4LU34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

361183:AMC99 RS03290
gene id: 361183:AMC99_RS03290
uniprot id: A0A0M3T9V8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

361183:AMC99 RS04860
gene id: 361183:AMC99_RS04860
uniprot id: A0A0M4MV28
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

361183:AMC99 RS05780
gene id: 361183:AMC99_RS05780
uniprot id: A0A0M4LUX4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

361183:AMC99 RS00230
gene id: 361183:AMC99_RS00230
uniprot id: A0A0M3T9I5
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS07350
gene id: 361183:AMC99_RS07350
uniprot id: A0A0M4M879
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

361183:AMC99 RS03520
gene id: 361183:AMC99_RS03520
uniprot id: A0A0M4M381
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

361183:AMC99 RS07185
gene id: 361183:AMC99_RS07185
uniprot id: A0A0M4M4L8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

361183:AMC99 RS03895
gene id: 361183:AMC99_RS03895
uniprot id: A0A0M4MFS5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

361183:AMC99 RS01775
gene id: 361183:AMC99_RS01775
uniprot id: A0A0M4MTX5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS05550
gene id: 361183:AMC99_RS05550
uniprot id: A0A0M4M416
names: Similarity
messages: Belongs to the UPF0102 family.

361183:AMC99 RS10975
gene id: 361183:AMC99_RS10975
uniprot id: A0A0M3TAY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

361183:AMC99 RS09985
gene id: 361183:AMC99_RS09985
uniprot id: A0A0M4MUT7
names: Similarity
messages: Belongs to the FGGY kinase family.

361183:AMC99 RS02135
gene id: 361183:AMC99_RS02135
uniprot id: A0A0M4MU18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

361183:AMC99 RS02615
gene id: 361183:AMC99_RS02615
uniprot id: A0A0M4LTR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

361183:AMC99 RS04395
gene id: 361183:AMC99_RS04395
uniprot id: A0A0M5L2G7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

361183:AMC99 RS06975
gene id: 361183:AMC99_RS06975
uniprot id: A0A0M4LVB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

361183:AMC99 RS03540
gene id: 361183:AMC99_RS03540
uniprot id: A0A0M3T9W7
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

361183:AMC99 RS09195
gene id: 361183:AMC99_RS09195
uniprot id: A0A0M4MUI6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

361183:AMC99 RS02770
gene id: 361183:AMC99_RS02770
uniprot id: A0A0M4LT63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

361183:AMC99 RS07985
gene id: 361183:AMC99_RS07985
uniprot id: A0A0M4MW63
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

361183:AMC99 RS05000
gene id: 361183:AMC99_RS05000
uniprot id: A0A0M4M3U9
names: Similarity
messages: Belongs to the RecJ family.

361183:AMC99 RS13580
gene id: 361183:AMC99_RS13580
uniprot id: A0A0M4M6U2
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

361183:AMC99 RS11370
gene id: 361183:AMC99_RS11370
uniprot id: A0A0M3TAZ7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

361183:AMC99 RS11225
gene id: 361183:AMC99_RS11225
uniprot id: A0A0M4MXE1
names: Similarity
messages: Belongs to the Nth/MutY family.

361183:AMC99 RS10660
gene id: 361183:AMC99_RS10660
uniprot id: A0A0M4M9G2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

361183:AMC99 RS02150
gene id: 361183:AMC99_RS02150
uniprot id: A0A0M4M2S2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

361183:AMC99 RS07855
gene id: 361183:AMC99_RS07855
uniprot id: A0A0M5KYN6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS07540
gene id: 361183:AMC99_RS07540
uniprot id: A0A0M5KYM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

361183:AMC99 RS11240
gene id: 361183:AMC99_RS11240
uniprot id: A0A0M4M603
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

361183:AMC99 RS05950
gene id: 361183:AMC99_RS05950
uniprot id: A0A0M4LUC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS09840
gene id: 361183:AMC99_RS09840
uniprot id: A0A0M4LVS6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

361183:AMC99 RS07395
gene id: 361183:AMC99_RS07395
uniprot id: A0A0M4MTV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

361183:AMC99 RS03380
gene id: 361183:AMC99_RS03380
uniprot id: A0A0M5KY94
names: Similarity
messages: Belongs to the Skp family.

361183:AMC99 RS11545
gene id: 361183:AMC99_RS11545
uniprot id: A0A0M3TAU2
names: Similarity
messages: Belongs to the peptidase M13 family.

361183:AMC99 RS03415
gene id: 361183:AMC99_RS03415
uniprot id: A0A0M4MFK5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

361183:AMC99 RS05640
gene id: 361183:AMC99_RS05640
uniprot id: A0A0M4MT86
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

361183:AMC99 RS01270
gene id: 361183:AMC99_RS01270
uniprot id: A0A0M3T9T4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS03095
gene id: 361183:AMC99_RS03095
uniprot id: A0A0M4LTX4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

361183:AMC99 RS13655
gene id: 361183:AMC99_RS13655
uniprot id: A0A0M4MJK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

361183:AMC99 RS04420
gene id: 361183:AMC99_RS04420
uniprot id: A0A0M3TA04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

361183:AMC99 RS13695
gene id: 361183:AMC99_RS13695
uniprot id: A0A0M4M6V9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

361183:AMC99 RS02365
gene id: 361183:AMC99_RS02365
uniprot id: A0A0M3T9Y0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS01950
gene id: 361183:AMC99_RS01950
uniprot id: A0A0M3T9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

361183:AMC99 RS12455
gene id: 361183:AMC99_RS12455
uniprot id: A0A0M4MA69
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

361183:AMC99 RS01170
gene id: 361183:AMC99_RS01170
uniprot id: A0A0M4MEQ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

361183:AMC99 RS02200
gene id: 361183:AMC99_RS02200
uniprot id: A0A0M4MU27
names: Subunit
messages: Homodimer.

361183:AMC99 RS07480
gene id: 361183:AMC99_RS07480
uniprot id: A0A0M4MW07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

361183:AMC99 RS01150
gene id: 361183:AMC99_RS01150
uniprot id: A0A0M4M5R9
names: Similarity
messages: Belongs to the Gfa family.

361183:AMC99 RS07835
gene id: 361183:AMC99_RS07835
uniprot id: A0A0M4MU12
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

361183:AMC99 RS05620
gene id: 361183:AMC99_RS05620
uniprot id: A0A0M4LU74
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

361183:AMC99 RS09200
gene id: 361183:AMC99_RS09200
uniprot id: A0A0M4LW37
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05940
gene id: 361183:AMC99_RS05940
uniprot id: A0A0M4M468
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

361183:AMC99 RS05965
gene id: 361183:AMC99_RS05965
uniprot id: A0A0M4MTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

361183:AMC99 RS06910
gene id: 361183:AMC99_RS06910
uniprot id: A0A0M4MTP5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

361183:AMC99 RS13000
gene id: 361183:AMC99_RS13000
uniprot id: A0A0M5KZ58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

361183:AMC99 RS06795
gene id: 361183:AMC99_RS06795
uniprot id: A0A0M4M812
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

361183:AMC99 RS01810
gene id: 361183:AMC99_RS01810
uniprot id: A0A0M3T9Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

361183:AMC99 RS03585
gene id: 361183:AMC99_RS03585
uniprot id: A0A0M4LTG3
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

361183:AMC99 RS12890
gene id: 361183:AMC99_RS12890
uniprot id: A0A0M4M6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS13130
gene id: 361183:AMC99_RS13130
uniprot id: A0A0M3TAZ8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

361183:AMC99 RS05580
gene id: 361183:AMC99_RS05580
uniprot id: A0A0M3TAA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

361183:AMC99 RS12845
gene id: 361183:AMC99_RS12845
uniprot id: A0A0M4MJ70
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

361183:AMC99 RS10060
gene id: 361183:AMC99_RS10060
uniprot id: A0A0M5KZU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS07135
gene id: 361183:AMC99_RS07135
uniprot id: A0A0M4LUT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

361183:AMC99 RS02710
gene id: 361183:AMC99_RS02710
uniprot id: A0A0M4LT58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

361183:AMC99 RS08795
gene id: 361183:AMC99_RS08795
uniprot id: A0A0M3TAH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

361183:AMC99 RS02610
gene id: 361183:AMC99_RS02610
uniprot id: A0A0M3T9Z0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

361183:AMC99 RS09625
gene id: 361183:AMC99_RS09625
uniprot id: A0A0M4M921
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

361183:AMC99 RS08345
gene id: 361183:AMC99_RS08345
uniprot id: A0A0M4M8K0
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

361183:AMC99 RS06920
gene id: 361183:AMC99_RS06920
uniprot id: A0A0M4M827
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

361183:AMC99 RS05465
gene id: 361183:AMC99_RS05465
uniprot id: A0A0M4M7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS04690
gene id: 361183:AMC99_RS04690
uniprot id: A0A0M3TA73
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

361183:AMC99 RS09855
gene id: 361183:AMC99_RS09855
uniprot id: A0A0M3TAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

361183:AMC99 RS08135
gene id: 361183:AMC99_RS08135
uniprot id: A0A0M3TAL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

361183:AMC99 RS10705
gene id: 361183:AMC99_RS10705
uniprot id: A0A0M4M9F4
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

361183:AMC99 RS09690
gene id: 361183:AMC99_RS09690
uniprot id: A0A0M5KYU5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

361183:AMC99 RS04235
gene id: 361183:AMC99_RS04235
uniprot id: A0A0M4MUT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

361183:AMC99 RS13005
gene id: 361183:AMC99_RS13005
uniprot id: A0A0M4MY11
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

361183:AMC99 RS09905
gene id: 361183:AMC99_RS09905
uniprot id: A0A0M3TAT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

361183:AMC99 RS11445
gene id: 361183:AMC99_RS11445
uniprot id: A0A0M4LWY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

361183:AMC99 RS09365
gene id: 361183:AMC99_RS09365
uniprot id: A0A0M4MHV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

361183:AMC99 RS03360
gene id: 361183:AMC99_RS03360
uniprot id: A0A0M4MS95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

361183:AMC99 RS04215
gene id: 361183:AMC99_RS04215
uniprot id: A0A0M4LUC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

361183:AMC99 RS13690
gene id: 361183:AMC99_RS13690
uniprot id: A0A0M4MAN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

361183:AMC99 RS05745
gene id: 361183:AMC99_RS05745
uniprot id: A0A0M3TAB2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS09785
gene id: 361183:AMC99_RS09785
uniprot id: A0A0M4MI01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

361183:AMC99 RS07870
gene id: 361183:AMC99_RS07870
uniprot id: A0A0M3TAE3
names: Similarity
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.

361183:AMC99 RS07680
gene id: 361183:AMC99_RS07680
uniprot id: A0A0M4M4S8
names: Similarity
messages: Belongs to the peptidase A24 family.

361183:AMC99 RS05935
gene id: 361183:AMC99_RS05935
uniprot id: A0A0M4M7N5
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS06085
gene id: 361183:AMC99_RS06085
uniprot id: A0A0M5L0B7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS08845
gene id: 361183:AMC99_RS08845
uniprot id: A0A0M4MWH1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

361183:AMC99 RS04425
gene id: 361183:AMC99_RS04425
uniprot id: A0A0M4MUW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

361183:AMC99 RS10390
gene id: 361183:AMC99_RS10390
uniprot id: A0A0M4LWJ0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

361183:AMC99 RS02930
gene id: 361183:AMC99_RS02930
uniprot id: A0A0M5KZ53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

361183:AMC99 RS08360
gene id: 361183:AMC99_RS08360
uniprot id: A0A0M4M509
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

361183:AMC99 RS13090
gene id: 361183:AMC99_RS13090
uniprot id: A0A0M4LWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

361183:AMC99 RS08640
gene id: 361183:AMC99_RS08640
uniprot id: A0A0M3TAG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

361183:AMC99 RS05520
gene id: 361183:AMC99_RS05520
uniprot id: A0A0M4LUT8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

361183:AMC99 RS08025
gene id: 361183:AMC99_RS08025
uniprot id: A0A0M4MU38
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

361183:AMC99 RS02320
gene id: 361183:AMC99_RS02320
uniprot id: A0A0M5KZ31
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS12370
gene id: 361183:AMC99_RS12370
uniprot id: A0A0M4MA41
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

361183:AMC99 RS13530
gene id: 361183:AMC99_RS13530
uniprot id: A0A0M4MJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

361183:AMC99 RS11910
gene id: 361183:AMC99_RS11910
uniprot id: A0A0M4MIV2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

361183:AMC99 RS02485
gene id: 361183:AMC99_RS02485
uniprot id: A0A0M4LTP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

361183:AMC99 RS11985
gene id: 361183:AMC99_RS11985
uniprot id: A0A0M4MVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS08405
gene id: 361183:AMC99_RS08405
uniprot id: A0A0M3TAG1
names: Similarity
messages: Belongs to the peptidase M16 family.

361183:AMC99 RS14070
gene id: 361183:AMC99_RS14070
uniprot id: A0A0M4M2C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

361183:AMC99 RS07125
gene id: 361183:AMC99_RS07125
uniprot id: A0A0M3TAB5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

361183:AMC99 RS11150
gene id: 361183:AMC99_RS11150
uniprot id: A0A0M5L7C5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

361183:AMC99 RS13260
gene id: 361183:AMC99_RS13260
uniprot id: A0A0M4MY39
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

361183:AMC99 RS07505
gene id: 361183:AMC99_RS07505
uniprot id: A0A0M4MH42
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

361183:AMC99 RS04335
gene id: 361183:AMC99_RS04335
uniprot id: A0A0M5L6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS11660
gene id: 361183:AMC99_RS11660
uniprot id: A0A0M4M659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

361183:AMC99 RS02455
gene id: 361183:AMC99_RS02455
uniprot id: A0A0M4M2W0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS01110
gene id: 361183:AMC99_RS01110
uniprot id: A0A0M4MEQ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

361183:AMC99 RS12940
gene id: 361183:AMC99_RS12940
uniprot id: A0A0M4MY04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

361183:AMC99 RS12930
gene id: 361183:AMC99_RS12930
uniprot id: A0A0M4MAA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

361183:AMC99 RS07435
gene id: 361183:AMC99_RS07435
uniprot id: A0A0M3TAJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS07320
gene id: 361183:AMC99_RS07320
uniprot id: A0A0M3TAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

361183:AMC99 RS12405
gene id: 361183:AMC99_RS12405
uniprot id: A0A0M4LWS0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS01230
gene id: 361183:AMC99_RS01230
uniprot id: A0A0M4LSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

361183:AMC99 RS06895
gene id: 361183:AMC99_RS06895
uniprot id: A0A0M4MGX5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates guanosine-37 in various tRNAs.

361183:AMC99 RS08415
gene id: 361183:AMC99_RS08415
uniprot id: A0A0M4M8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

361183:AMC99 RS13660
gene id: 361183:AMC99_RS13660
uniprot id: A0A0M5L7I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

361183:AMC99 RS13165
gene id: 361183:AMC99_RS13165
uniprot id: A0A0M5KZ67
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

361183:AMC99 RS06465
gene id: 361183:AMC99_RS06465
uniprot id: A0A0M4LV58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

361183:AMC99 RS03420
gene id: 361183:AMC99_RS03420
uniprot id: A0A0M3TA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

361183:AMC99 RS11945
gene id: 361183:AMC99_RS11945
uniprot id: A0A0M4MXP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
messages: Cell inner membrane
messages: Intake of glucose and galactose.
messages: Membrane

361183:AMC99 RS00990
gene id: 361183:AMC99_RS00990
uniprot id: A0A0M4LSI9
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

361183:AMC99 RS01065
gene id: 361183:AMC99_RS01065
uniprot id: A0A0M3T9M0
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

361183:AMC99 RS12880
gene id: 361183:AMC99_RS12880
uniprot id: A0A0M3TAY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

361183:AMC99 RS06810
gene id: 361183:AMC99_RS06810
uniprot id: A0A0M4MVR8
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

361183:AMC99 RS02595
gene id: 361183:AMC99_RS02595
uniprot id: A0A0M4MF92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

361183:AMC99 RS06450
gene id: 361183:AMC99_RS06450
uniprot id: A0A0M4MGR9
names: Similarity
messages: Belongs to the glutathione peroxidase family.

361183:AMC99 RS04595
gene id: 361183:AMC99_RS04595
uniprot id: A0A0M4LUG7
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

361183:AMC99 RS11580
gene id: 361183:AMC99_RS11580
uniprot id: A0A0M5KZ00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

361183:AMC99 RS01010
gene id: 361183:AMC99_RS01010
uniprot id: A0A0M4LT60
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

361183:AMC99 RS11055
gene id: 361183:AMC99_RS11055
uniprot id: A0A0M4M5X9
names: Similarity
messages: Belongs to the YciI family.

361183:AMC99 RS03365
gene id: 361183:AMC99_RS03365
uniprot id: A0A0M3TA19
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS02605
gene id: 361183:AMC99_RS02605
uniprot id: A0A0M4MRZ5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

361183:AMC99 RS01115
gene id: 361183:AMC99_RS01115
uniprot id: A0A0M5KZV8
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS06985
gene id: 361183:AMC99_RS06985
uniprot id: A0A0M4M833
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

361183:AMC99 RS06875
gene id: 361183:AMC99_RS06875
uniprot id: A0A0M4M801
names: Similarity
messages: Belongs to the DDAH family.

361183:AMC99 RS10810
gene id: 361183:AMC99_RS10810
uniprot id: A0A0M3TAR1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS12925
gene id: 361183:AMC99_RS12925
uniprot id: A0A0M3TAZ0
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

361183:AMC99 RS03515
gene id: 361183:AMC99_RS03515
uniprot id: A0A0M4M6P2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

361183:AMC99 RS07145
gene id: 361183:AMC99_RS07145
uniprot id: A0A0M5L6X8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

361183:AMC99 RS12910
gene id: 361183:AMC99_RS12910
uniprot id: A0A0M5L0Y8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

361183:AMC99 RS08625
gene id: 361183:AMC99_RS08625
uniprot id: A0A0M4LVW8
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

361183:AMC99 RS12335
gene id: 361183:AMC99_RS12335
uniprot id: A0A0M4M6F1
names: Similarity
messages: Belongs to the HesB/IscA family.

361183:AMC99 RS04585
gene id: 361183:AMC99_RS04585
uniprot id: A0A0M4MSS3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

361183:AMC99 RS06960
gene id: 361183:AMC99_RS06960
uniprot id: A0A0M4MGY2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

361183:AMC99 RS09175
gene id: 361183:AMC99_RS09175
uniprot id: A0A0M3TAQ2
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

361183:AMC99 RS07605
gene id: 361183:AMC99_RS07605
uniprot id: A0A0M4MW22
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

361183:AMC99 RS04195
gene id: 361183:AMC99_RS04195
uniprot id: A0A0M3TA53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS12645
gene id: 361183:AMC99_RS12645
uniprot id: A0A0M4M6J2
names: Similarity
messages: Belongs to the peptidase S41A family.

361183:AMC99 RS12305
gene id: 361183:AMC99_RS12305
uniprot id: A0A0M4LXA5
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

361183:AMC99 RS05945
gene id: 361183:AMC99_RS05945
uniprot id: A0A0M3TAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

361183:AMC99 RS07550
gene id: 361183:AMC99_RS07550
uniprot id: A0A0M4M897
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

361183:AMC99 RS03180
gene id: 361183:AMC99_RS03180
uniprot id: A0A0M5KY86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

361183:AMC99 RS07660
gene id: 361183:AMC99_RS07660
uniprot id: A0A0M5L581
names: Similarity
messages: Belongs to the GSP E family.

361183:AMC99 RS09605
gene id: 361183:AMC99_RS09605
uniprot id: A0A0M3TAR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

361183:AMC99 RS03575
gene id: 361183:AMC99_RS03575
uniprot id: A0A0M4M6Q1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

361183:AMC99 RS09870
gene id: 361183:AMC99_RS09870
uniprot id: A0A0M4LWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS05350
gene id: 361183:AMC99_RS05350
uniprot id: A0A0M4M7G8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Lysosome

361183:AMC99 RS09080
gene id: 361183:AMC99_RS09080
uniprot id: A0A0M4LW22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

361183:AMC99 RS08840
gene id: 361183:AMC99_RS08840
uniprot id: A0A0M5KZP6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

361183:AMC99 RS08195
gene id: 361183:AMC99_RS08195
uniprot id: A0A0M4MHF0
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

361183:AMC99 RS10055
gene id: 361183:AMC99_RS10055
uniprot id: A0A0M4M975
names: Similarity
messages: Belongs to the ArsC family.

361183:AMC99 RS05590
gene id: 361183:AMC99_RS05590
uniprot id: A0A0M4M7J8
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

361183:AMC99 RS08500
gene id: 361183:AMC99_RS08500
uniprot id: A0A0M3TAG3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

361183:AMC99 RS07420
gene id: 361183:AMC99_RS07420
uniprot id: A0A0M4MVZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

361183:AMC99 RS11500
gene id: 361183:AMC99_RS11500
uniprot id: A0A0M4MVD0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS01845
gene id: 361183:AMC99_RS01845
uniprot id: A0A0M4M2P0
names: Similarity
messages: Belongs to the LOG family.

361183:AMC99 RS05810
gene id: 361183:AMC99_RS05810
uniprot id: A0A0M4M453
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

361183:AMC99 RS03835
gene id: 361183:AMC99_RS03835
uniprot id: A0A0M3T9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS02490
gene id: 361183:AMC99_RS02490
uniprot id: A0A0M3T9S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

361183:AMC99 RS00665
gene id: 361183:AMC99_RS00665
uniprot id: A0A0M4M5S0
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS01305
gene id: 361183:AMC99_RS01305
uniprot id: A0A0M4MRH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

361183:AMC99 RS12795
gene id: 361183:AMC99_RS12795
uniprot id: A0A0M4MVV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

361183:AMC99 RS13395
gene id: 361183:AMC99_RS13395
uniprot id: A0A0M4M6S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

361183:AMC99 RS10005
gene id: 361183:AMC99_RS10005
uniprot id: A0A0M5KYV4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

361183:AMC99 RS06235
gene id: 361183:AMC99_RS06235
uniprot id: A0A0M5KYI0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

361183:AMC99 RS06760
gene id: 361183:AMC99_RS06760
uniprot id: A0A0M4M4G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

361183:AMC99 RS05230
gene id: 361183:AMC99_RS05230
uniprot id: A0A0M3TA94
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

361183:AMC99 RS07035
gene id: 361183:AMC99_RS07035
uniprot id: A0A0M4LVC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

361183:AMC99 RS02115
gene id: 361183:AMC99_RS02115
uniprot id: A0A0M3T9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

361183:AMC99 RS02435
gene id: 361183:AMC99_RS02435
uniprot id: A0A0M5KY63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

361183:AMC99 RS08775
gene id: 361183:AMC99_RS08775
uniprot id: A0A0M4MWG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

361183:AMC99 RS09885
gene id: 361183:AMC99_RS09885
uniprot id: A0A0M3TAM5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS06880
gene id: 361183:AMC99_RS06880
uniprot id: A0A0M3TAA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS12650
gene id: 361183:AMC99_RS12650
uniprot id: A0A0M3TB48
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS01575
gene id: 361183:AMC99_RS01575
uniprot id: A0A0M4MTV6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

361183:AMC99 RS08715
gene id: 361183:AMC99_RS08715
uniprot id: A0A0M4M8P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

361183:AMC99 RS09020
gene id: 361183:AMC99_RS09020
uniprot id: A0A0M4MUF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

361183:AMC99 RS09560
gene id: 361183:AMC99_RS09560
uniprot id: A0A0M4LW85
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

361183:AMC99 RS04780
gene id: 361183:AMC99_RS04780
uniprot id: A0A0M4MSU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS03040
gene id: 361183:AMC99_RS03040
uniprot id: A0A0M3TA07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

361183:AMC99 RS09860
gene id: 361183:AMC99_RS09860
uniprot id: A0A0M5L791
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

361183:AMC99 RS07600
gene id: 361183:AMC99_RS07600
uniprot id: A0A0M5KZK5
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05925
gene id: 361183:AMC99_RS05925
uniprot id: A0A0M3TA64
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

361183:AMC99 RS01740
gene id: 361183:AMC99_RS01740
uniprot id: A0A0M5KZX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.
messages: Membrane

361183:AMC99 RS09295
gene id: 361183:AMC99_RS09295
uniprot id: A0A0M4LVK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

361183:AMC99 RS10815
gene id: 361183:AMC99_RS10815
uniprot id: A0A0M4MID5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

361183:AMC99 RS03530
gene id: 361183:AMC99_RS03530
uniprot id: A0A0M4MFM7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

361183:AMC99 RS07490
gene id: 361183:AMC99_RS07490
uniprot id: A0A0M4M888
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

361183:AMC99 RS06220
gene id: 361183:AMC99_RS06220
uniprot id: A0A0M4LV27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

361183:AMC99 RS11245
gene id: 361183:AMC99_RS11245
uniprot id: A0A0M4LWB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

361183:AMC99 RS09245
gene id: 361183:AMC99_RS09245
uniprot id: A0A0M5L770
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

361183:AMC99 RS12340
gene id: 361183:AMC99_RS12340
uniprot id: A0A0M4LWR0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

361183:AMC99 RS02790
gene id: 361183:AMC99_RS02790
uniprot id: A0A0M4MS17
names: Similarity
messages: Belongs to the threonine synthase family.

361183:AMC99 RS04495
gene id: 361183:AMC99_RS04495
uniprot id: A0A0M4M728
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

361183:AMC99 RS02630
gene id: 361183:AMC99_RS02630
uniprot id: A0A0M4MU82
names: Similarity
messages: Belongs to the pirin family.

361183:AMC99 RS00985
gene id: 361183:AMC99_RS00985
uniprot id: A0A0M3T9S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

361183:AMC99 RS04305
gene id: 361183:AMC99_RS04305
uniprot id: A0A0M4M704
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

361183:AMC99 RS05080
gene id: 361183:AMC99_RS05080
uniprot id: A0A0M3TA88
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS13445
gene id: 361183:AMC99_RS13445
uniprot id: A0A0M4MY63
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

361183:AMC99 RS07015
gene id: 361183:AMC99_RS07015
uniprot id: A0A0M4MGZ0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

361183:AMC99 RS01805
gene id: 361183:AMC99_RS01805
uniprot id: A0A0M5L6I7
names: Similarity
messages: Belongs to the Nudix hydrolase family.

361183:AMC99 RS13610
gene id: 361183:AMC99_RS13610
uniprot id: A0A0M4LXQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

361183:AMC99 RS07690
gene id: 361183:AMC99_RS07690
uniprot id: A0A0M4LV01
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

361183:AMC99 RS11030
gene id: 361183:AMC99_RS11030
uniprot id: A0A0M4M9J7
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

361183:AMC99 RS02035
gene id: 361183:AMC99_RS02035
uniprot id: A0A0M4MF20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

361183:AMC99 RS02570
gene id: 361183:AMC99_RS02570
uniprot id: A0A0M4MU75
names: Similarity
messages: Belongs to the DEAD box helicase family.

361183:AMC99 RS01370
gene id: 361183:AMC99_RS01370
uniprot id: A0A0M4LTA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

361183:AMC99 RS07510
gene id: 361183:AMC99_RS07510
uniprot id: A0A0M5L2R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

361183:AMC99 RS03595
gene id: 361183:AMC99_RS03595
uniprot id: A0A0M4MFN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

361183:AMC99 RS13550
gene id: 361183:AMC99_RS13550
uniprot id: A0A0M4LXP9
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

361183:AMC99 RS11740
gene id: 361183:AMC99_RS11740
uniprot id: A0A0M3TAU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS09480
gene id: 361183:AMC99_RS09480
uniprot id: A0A0M5L0M9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

361183:AMC99 RS02500
gene id: 361183:AMC99_RS02500
uniprot id: A0A0M5KY52
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

361183:AMC99 RS00295
gene id: 361183:AMC99_RS00295
uniprot id: A0A0M3T9P3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

361183:AMC99 RS02315
gene id: 361183:AMC99_RS02315
uniprot id: A0A0M3T9X8
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS04100
gene id: 361183:AMC99_RS04100
uniprot id: A0A0M3TA49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

361183:AMC99 RS09455
gene id: 361183:AMC99_RS09455
uniprot id: A0A0M3TAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS02155
gene id: 361183:AMC99_RS02155
uniprot id: A0A0M4LSY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

361183:AMC99 RS07425
gene id: 361183:AMC99_RS07425
uniprot id: A0A0M4M880
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

361183:AMC99 RS09390
gene id: 361183:AMC99_RS09390
uniprot id: A0A0M5KYT5
names: Similarity
messages: Belongs to the peptidase A24 family.

361183:AMC99 RS10375
gene id: 361183:AMC99_RS10375
uniprot id: A0A0M3TAV5
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS10820
gene id: 361183:AMC99_RS10820
uniprot id: A0A0M5L7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

361183:AMC99 RS03140
gene id: 361183:AMC99_RS03140
uniprot id: A0A0M4LTA8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

361183:AMC99 RS12905
gene id: 361183:AMC99_RS12905
uniprot id: A0A0M4MJ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

361183:AMC99 RS00685
gene id: 361183:AMC99_RS00685
uniprot id: A0A0M3T9K4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

361183:AMC99 RS07820
gene id: 361183:AMC99_RS07820
uniprot id: A0A0M3TAE1
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

361183:AMC99 RS07470
gene id: 361183:AMC99_RS07470
uniprot id: A0A0M4M894
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

361183:AMC99 RS02070
gene id: 361183:AMC99_RS02070
uniprot id: A0A0M5L4P9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS03350
gene id: 361183:AMC99_RS03350
uniprot id: A0A0M4MFJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

361183:AMC99 RS13815
gene id: 361183:AMC99_RS13815
uniprot id: A0A0M4LT68
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

361183:AMC99 RS06935
gene id: 361183:AMC99_RS06935
uniprot id: A0A0M3TAA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS03525
gene id: 361183:AMC99_RS03525
uniprot id: A0A0M4LTF5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS03065
gene id: 361183:AMC99_RS03065
uniprot id: A0A0M3T9V0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

361183:AMC99 RS09925
gene id: 361183:AMC99_RS09925
uniprot id: A0A0M4MUS7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS01635
gene id: 361183:AMC99_RS01635
uniprot id: A0A0M4M646
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.

361183:AMC99 RS04705
gene id: 361183:AMC99_RS04705
uniprot id: A0A0M5L2H7
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

361183:AMC99 RS03915
gene id: 361183:AMC99_RS03915
uniprot id: A0A0M4LU79
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

361183:AMC99 RS01925
gene id: 361183:AMC99_RS01925
uniprot id: A0A0M3T9W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

361183:AMC99 RS02875
gene id: 361183:AMC99_RS02875
uniprot id: A0A0M4MUB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

361183:AMC99 RS04155
gene id: 361183:AMC99_RS04155
uniprot id: A0A0M4MSL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

361183:AMC99 RS07360
gene id: 361183:AMC99_RS07360
uniprot id: A0A0M4MVY5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

361183:AMC99 RS07790
gene id: 361183:AMC99_RS07790
uniprot id: A0A0M5KYM7
names: Similarity
messages: Belongs to the GST superfamily.

361183:AMC99 RS10365
gene id: 361183:AMC99_RS10365
uniprot id: A0A0M4LVZ2
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS01780
gene id: 361183:AMC99_RS01780
uniprot id: A0A0M3T9V5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS13050
gene id: 361183:AMC99_RS13050
uniprot id: A0A0M3TB59
names: Similarity
messages: Belongs to the phosphohexose mutase family.

361183:AMC99 RS05885
gene id: 361183:AMC99_RS05885
uniprot id: A0A0M4MGK3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

361183:AMC99 RS00100
gene id: 361183:AMC99_RS00100
uniprot id: A0A0M5KXZ1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

361183:AMC99 RS07230
gene id: 361183:AMC99_RS07230
uniprot id: A0A0M5KYL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

361183:AMC99 RS02975
gene id: 361183:AMC99_RS02975
uniprot id: A0A0M4MS44
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

361183:AMC99 RS07570
gene id: 361183:AMC99_RS07570
uniprot id: A0A0M4MH49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

361183:AMC99 RS06200
gene id: 361183:AMC99_RS06200
uniprot id: A0A0M4LUF9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

361183:AMC99 RS09445
gene id: 361183:AMC99_RS09445
uniprot id: A0A0M4M8Z5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

361183:AMC99 RS06150
gene id: 361183:AMC99_RS06150
uniprot id: A0A0M5L6X4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

361183:AMC99 RS05070
gene id: 361183:AMC99_RS05070
uniprot id: A0A0M5KYE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

361183:AMC99 RS02730
gene id: 361183:AMC99_RS02730
uniprot id: A0A0M4LTS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

361183:AMC99 RS03430
gene id: 361183:AMC99_RS03430
uniprot id: A0A0M4LU14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

361183:AMC99 RS09890
gene id: 361183:AMC99_RS09890
uniprot id: A0A0M4MWV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

361183:AMC99 RS06765
gene id: 361183:AMC99_RS06765
uniprot id: A0A0M4LUN4
names: Similarity
messages: Belongs to the fabD family.

361183:AMC99 RS09035
gene id: 361183:AMC99_RS09035
uniprot id: A0A0M3TAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

361183:AMC99 RS13720
gene id: 361183:AMC99_RS13720
uniprot id: A0A0M4MW64
names: Similarity
messages: Belongs to the histone deacetylase family.

361183:AMC99 RS12375
gene id: 361183:AMC99_RS12375
uniprot id: A0A0M5KZ36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

361183:AMC99 RS09650
gene id: 361183:AMC99_RS09650
uniprot id: A0A0M4M5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS06890
gene id: 361183:AMC99_RS06890
uniprot id: A0A0M4LUP9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

361183:AMC99 RS09945
gene id: 361183:AMC99_RS09945
uniprot id: A0A0M5KYV2
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

361183:AMC99 RS01000
gene id: 361183:AMC99_RS01000
uniprot id: A0A0M5L255
names: Similarity
messages: Belongs to the UPF0262 family.

361183:AMC99 RS04955
gene id: 361183:AMC99_RS04955
uniprot id: A0A0M5L6Q9
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

361183:AMC99 RS11120
gene id: 361183:AMC99_RS11120
uniprot id: A0A0M3TAS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

361183:AMC99 RS10885
gene id: 361183:AMC99_RS10885
uniprot id: A0A0M3TAX6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

361183:AMC99 RS13560
gene id: 361183:AMC99_RS13560
uniprot id: A0A0M5L5T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS00960
gene id: 361183:AMC99_RS00960
uniprot id: A0A0M5KY09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

361183:AMC99 RS08225
gene id: 361183:AMC99_RS08225
uniprot id: A0A0M5KZM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

361183:AMC99 RS11700
gene id: 361183:AMC99_RS11700
uniprot id: A0A0M4M9U7
names: Similarity
messages: Belongs to the cytochrome P450 family.

361183:AMC99 RS05145
gene id: 361183:AMC99_RS05145
uniprot id: A0A0M4LUN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

361183:AMC99 RS03830
gene id: 361183:AMC99_RS03830
uniprot id: A0A0M4LTJ1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

361183:AMC99 RS02055
gene id: 361183:AMC99_RS02055
uniprot id: A0A0M4LTI8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS06555
gene id: 361183:AMC99_RS06555
uniprot id: A0A0M4M7W2
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS06170
gene id: 361183:AMC99_RS06170
uniprot id: A0A0M5KYI4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

361183:AMC99 RS00515
gene id: 361183:AMC99_RS00515
uniprot id: A0A0M4MEG5
names: Similarity
messages: Belongs to the hcp beta-lactamase family.

361183:AMC99 RS09000
gene id: 361183:AMC99_RS09000
uniprot id: A0A0M4LVG1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

361183:AMC99 RS05535
gene id: 361183:AMC99_RS05535
uniprot id: A0A0M5KYG3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

361183:AMC99 RS11455
gene id: 361183:AMC99_RS11455
uniprot id: A0A0M4M9Q9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

361183:AMC99 RS04970
gene id: 361183:AMC99_RS04970
uniprot id: A0A0M3TA26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

361183:AMC99 RS11955
gene id: 361183:AMC99_RS11955
uniprot id: A0A0M4MA10
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS09575
gene id: 361183:AMC99_RS09575
uniprot id: A0A0M4MWR4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

361183:AMC99 RS06990
gene id: 361183:AMC99_RS06990
uniprot id: A0A0M5KZI5
names: Function
names: Similarity
messages: A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.
messages: Belongs to the bacterial AtpI family.

361183:AMC99 RS09865
gene id: 361183:AMC99_RS09865
uniprot id: A0A0M4MUS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS09105
gene id: 361183:AMC99_RS09105
uniprot id: A0A0M3TAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

361183:AMC99 RS08490
gene id: 361183:AMC99_RS08490
uniprot id: A0A0M4MHJ3
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05555
gene id: 361183:AMC99_RS05555
uniprot id: A0A0M4LU62
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

361183:AMC99 RS00740
gene id: 361183:AMC99_RS00740
uniprot id: A0A0M4M5L2
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS04775
gene id: 361183:AMC99_RS04775
uniprot id: A0A0M3TA18
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

361183:AMC99 RS10605
gene id: 361183:AMC99_RS10605
uniprot id: A0A0M3TAQ3
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

361183:AMC99 RS04345
gene id: 361183:AMC99_RS04345
uniprot id: A0A0M4LUD8
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

361183:AMC99 RS06540
gene id: 361183:AMC99_RS06540
uniprot id: A0A0M3TAE6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

361183:AMC99 RS06390
gene id: 361183:AMC99_RS06390
uniprot id: A0A0M3TAE0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

361183:AMC99 RS10865
gene id: 361183:AMC99_RS10865
uniprot id: A0A0M3TAR3
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

361183:AMC99 RS04940
gene id: 361183:AMC99_RS04940
uniprot id: A0A0M3TA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

361183:AMC99 RS11440
gene id: 361183:AMC99_RS11440
uniprot id: A0A0M4MVC3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

361183:AMC99 RS05200
gene id: 361183:AMC99_RS05200
uniprot id: A0A0M4MT11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS03995
gene id: 361183:AMC99_RS03995
uniprot id: A0A0M4MUQ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

361183:AMC99 RS08615
gene id: 361183:AMC99_RS08615
uniprot id: A0A0M5L750
names: Similarity
messages: Belongs to the peptidase C56 family.

361183:AMC99 RS05375
gene id: 361183:AMC99_RS05375
uniprot id: A0A0M4M3Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

361183:AMC99 RS09300
gene id: 361183:AMC99_RS09300
uniprot id: A0A0M3TAJ1
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

361183:AMC99 RS00425
gene id: 361183:AMC99_RS00425
uniprot id: A0A0M3T9J4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

361183:AMC99 RS04380
gene id: 361183:AMC99_RS04380
uniprot id: A0A0M4LTR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

361183:AMC99 RS02050
gene id: 361183:AMC99_RS02050
uniprot id: A0A0M4MRS6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

361183:AMC99 RS06140
gene id: 361183:AMC99_RS06140
uniprot id: A0A0M4MGN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS11460
gene id: 361183:AMC99_RS11460
uniprot id: A0A0M5KZ02
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

361183:AMC99 RS07215
gene id: 361183:AMC99_RS07215
uniprot id: A0A0M4LVE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rickettsiale 17 kDa surface antigen family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS02355
gene id: 361183:AMC99_RS02355
uniprot id: A0A0M5L000
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS06380
gene id: 361183:AMC99_RS06380
uniprot id: A0A0M4LUI9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS04480
gene id: 361183:AMC99_RS04480
uniprot id: A0A0M5KZA6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS00790
gene id: 361183:AMC99_RS00790
uniprot id: A0A0M5KYY9
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

361183:AMC99 RS13185
gene id: 361183:AMC99_RS13185
uniprot id: A0A0M4MAE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

361183:AMC99 RS09935
gene id: 361183:AMC99_RS09935
uniprot id: A0A0M3TAM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

361183:AMC99 RS02230
gene id: 361183:AMC99_RS02230
uniprot id: A0A0M5L297
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

361183:AMC99 RS07345
gene id: 361183:AMC99_RS07345
uniprot id: A0A0M4LVF8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

361183:AMC99 RS09375
gene id: 361183:AMC99_RS09375
uniprot id: A0A0M5L2X7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

361183:AMC99 RS05280
gene id: 361183:AMC99_RS05280
uniprot id: A0A0M4M7F9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

361183:AMC99 RS08610
gene id: 361183:AMC99_RS08610
uniprot id: A0A0M3TAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

361183:AMC99 RS00095
gene id: 361183:AMC99_RS00095
uniprot id: A0A0M3T9N5
names: Cofactor
names: Similarity
messages: Belongs to the bacterial PQQ dehydrogenase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Binds 1 PQQ group per subunit.
messages: Binds 1 heme c group per subunit.

361183:AMC99 RS03645
gene id: 361183:AMC99_RS03645
uniprot id: A0A0M3T9X1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS10385
gene id: 361183:AMC99_RS10385
uniprot id: A0A0M4MUY9
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

361183:AMC99 RS01240
gene id: 361183:AMC99_RS01240
uniprot id: A0A0M5L6E2
names: Similarity
messages: Belongs to the Tim44 family.

361183:AMC99 RS04385
gene id: 361183:AMC99_RS04385
uniprot id: A0A0M4MFY0
names: Similarity
messages: Belongs to the DprA/Smf family.

361183:AMC99 RS01280
gene id: 361183:AMC99_RS01280
uniprot id: A0A0M4M2H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

361183:AMC99 RS07720
gene id: 361183:AMC99_RS07720
uniprot id: A0A0M4M8C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

361183:AMC99 RS02820
gene id: 361183:AMC99_RS02820
uniprot id: A0A0M4M6E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

361183:AMC99 RS03960
gene id: 361183:AMC99_RS03960
uniprot id: A0A0M4MFT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

361183:AMC99 RS06945
gene id: 361183:AMC99_RS06945
uniprot id: A0A0M4M814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

361183:AMC99 RS09585
gene id: 361183:AMC99_RS09585
uniprot id: A0A0M3TAK4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

361183:AMC99 RS07520
gene id: 361183:AMC99_RS07520
uniprot id: A0A0M4MTW8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

361183:AMC99 RS07565
gene id: 361183:AMC99_RS07565
uniprot id: A0A0M3TAD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

361183:AMC99 RS11325
gene id: 361183:AMC99_RS11325
uniprot id: A0A0M4LWW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the OsmX family.
messages: In the N-terminal section; belongs to the binding-protein-dependent transport system permease family.

361183:AMC99 RS10150
gene id: 361183:AMC99_RS10150
uniprot id: A0A0M4LVW6
names: Similarity
messages: Belongs to the cytochrome P450 family.

361183:AMC99 RS07560
gene id: 361183:AMC99_RS07560
uniprot id: A0A0M4LUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

361183:AMC99 RS11785
gene id: 361183:AMC99_RS11785
uniprot id: A0A0M3TAU7
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

361183:AMC99 RS03335
gene id: 361183:AMC99_RS03335
uniprot id: A0A0M4M361
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

361183:AMC99 RS11010
gene id: 361183:AMC99_RS11010
uniprot id: A0A0M5KYZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

361183:AMC99 RS04790
gene id: 361183:AMC99_RS04790
uniprot id: A0A0M4M794
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

361183:AMC99 RS07765
gene id: 361183:AMC99_RS07765
uniprot id: A0A0M3TAD9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

361183:AMC99 RS05340
gene id: 361183:AMC99_RS05340
uniprot id: A0A0M3TA98
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

361183:AMC99 RS04665
gene id: 361183:AMC99_RS04665
uniprot id: A0A0M5KYD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS05660
gene id: 361183:AMC99_RS05660
uniprot id: A0A0M3TA54
names: Similarity
messages: Belongs to the alanine racemase family.

361183:AMC99 RS10630
gene id: 361183:AMC99_RS10630
uniprot id: A0A0M5L324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS02350
gene id: 361183:AMC99_RS02350
uniprot id: A0A0M4MF61
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS04660
gene id: 361183:AMC99_RS04660
uniprot id: A0A0M4M774
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

361183:AMC99 RS07055
gene id: 361183:AMC99_RS07055
uniprot id: A0A0M4MVU9
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

361183:AMC99 RS09075
gene id: 361183:AMC99_RS09075
uniprot id: A0A0M3TAP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

361183:AMC99 RS02430
gene id: 361183:AMC99_RS02430
uniprot id: A0A0M4M6D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

361183:AMC99 RS00105
gene id: 361183:AMC99_RS00105
uniprot id: A0A0M4MTB4
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS04900
gene id: 361183:AMC99_RS04900
uniprot id: A0A0M4MSW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

361183:AMC99 RS06750
gene id: 361183:AMC99_RS06750
uniprot id: A0A0M3TAF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

361183:AMC99 RS06175
gene id: 361183:AMC99_RS06175
uniprot id: A0A0M3TA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS13595
gene id: 361183:AMC99_RS13595
uniprot id: A0A0M3TB77
names: Similarity
messages: Belongs to the AAA ATPase family.

361183:AMC99 RS08420
gene id: 361183:AMC99_RS08420
uniprot id: A0A0M4M512
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

361183:AMC99 RS02935
gene id: 361183:AMC99_RS02935
uniprot id: A0A0M3T9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

361183:AMC99 RS05920
gene id: 361183:AMC99_RS05920
uniprot id: A0A0M5KYG9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

361183:AMC99 RS06850
gene id: 361183:AMC99_RS06850
uniprot id: A0A0M3TAG8
names: Similarity
messages: Belongs to the Gfa family.

361183:AMC99 RS11695
gene id: 361183:AMC99_RS11695
uniprot id: A0A0M3TAU5
names: Similarity
messages: Belongs to the UDPGP type 2 family.

361183:AMC99 RS10900
gene id: 361183:AMC99_RS10900
uniprot id: A0A0M4M9H9
names: Similarity
messages: Belongs to the cytochrome P450 family.

361183:AMC99 RS03425
gene id: 361183:AMC99_RS03425
uniprot id: A0A0M4MSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

361183:AMC99 RS10930
gene id: 361183:AMC99_RS10930
uniprot id: A0A0M3TAX8
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

361183:AMC99 RS08565
gene id: 361183:AMC99_RS08565
uniprot id: A0A0M3TAM8
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS06600
gene id: 361183:AMC99_RS06600
uniprot id: A0A0M4M7Y9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

361183:AMC99 RS02950
gene id: 361183:AMC99_RS02950
uniprot id: A0A0M4M316
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

361183:AMC99 RS03660
gene id: 361183:AMC99_RS03660
uniprot id: A0A0M4MFP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS05210
gene id: 361183:AMC99_RS05210
uniprot id: A0A0M3TA36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

361183:AMC99 RS06250
gene id: 361183:AMC99_RS06250
uniprot id: A0A0M4M7S2
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS08995
gene id: 361183:AMC99_RS08995
uniprot id: A0A0M4M578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

361183:AMC99 RS00785
gene id: 361183:AMC99_RS00785
uniprot id: A0A0M4M5T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

361183:AMC99 RS01295
gene id: 361183:AMC99_RS01295
uniprot id: A0A0M3T9N0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

361183:AMC99 RS05635
gene id: 361183:AMC99_RS05635
uniprot id: A0A0M5L2K7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS11040
gene id: 361183:AMC99_RS11040
uniprot id: A0A0M5KZX3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

361183:AMC99 RS02475
gene id: 361183:AMC99_RS02475
uniprot id: A0A0M5L6H8
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

361183:AMC99 RS11885
gene id: 361183:AMC99_RS11885
uniprot id: A0A0M3TAV0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS04870
gene id: 361183:AMC99_RS04870
uniprot id: A0A0M3TA22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

361183:AMC99 RS03500
gene id: 361183:AMC99_RS03500
uniprot id: A0A0M5KY96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

361183:AMC99 RS01030
gene id: 361183:AMC99_RS01030
uniprot id: A0A0M4MTN5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

361183:AMC99 RS08315
gene id: 361183:AMC99_RS08315
uniprot id: A0A0M4MU81
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

361183:AMC99 RS07535
gene id: 361183:AMC99_RS07535
uniprot id: A0A0M3TAJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

361183:AMC99 RS02870
gene id: 361183:AMC99_RS02870
uniprot id: A0A0M5KY76
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

361183:AMC99 RS13115
gene id: 361183:AMC99_RS13115
uniprot id: A0A0M4LXJ9
names: Similarity
messages: Belongs to the FBPase class 2 family.

361183:AMC99 RS09430
gene id: 361183:AMC99_RS09430
uniprot id: A0A0M5KYU1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS01765
gene id: 361183:AMC99_RS01765
uniprot id: A0A0M5L4P0
names: Similarity
messages: Belongs to the OmpW/AlkL family.

361183:AMC99 RS12500
gene id: 361183:AMC99_RS12500
uniprot id: A0A0M3TB42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

361183:AMC99 RS07440
gene id: 361183:AMC99_RS07440
uniprot id: A0A0M4LUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

361183:AMC99 RS12970
gene id: 361183:AMC99_RS12970
uniprot id: A0A0M5L7K1
names: Subunit
messages: Homotetramer.

361183:AMC99 RS11110
gene id: 361183:AMC99_RS11110
uniprot id: A0A0M4MXC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

361183:AMC99 RS03600
gene id: 361183:AMC99_RS03600
uniprot id: A0A0M5L038
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

361183:AMC99 RS06125
gene id: 361183:AMC99_RS06125
uniprot id: A0A0M3TA72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS02420
gene id: 361183:AMC99_RS02420
uniprot id: A0A0M4MRX3
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

361183:AMC99 RS12210
gene id: 361183:AMC99_RS12210
uniprot id: A0A0M4M6D5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

361183:AMC99 RS07875
gene id: 361183:AMC99_RS07875
uniprot id: A0A0M4M4U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

361183:AMC99 RS09045
gene id: 361183:AMC99_RS09045
uniprot id: A0A0M4MWJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS02190
gene id: 361183:AMC99_RS02190
uniprot id: A0A0M5KY42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

361183:AMC99 RS00810
gene id: 361183:AMC99_RS00810
uniprot id: A0A0M4M2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

361183:AMC99 RS04610
gene id: 361183:AMC99_RS04610
uniprot id: A0A0M4MUZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

361183:AMC99 RS11690
gene id: 361183:AMC99_RS11690
uniprot id: A0A0M4LX20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS12390
gene id: 361183:AMC99_RS12390
uniprot id: A0A0M4MA60
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

361183:AMC99 RS10110
gene id: 361183:AMC99_RS10110
uniprot id: A0A0M4LWF6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

361183:AMC99 RS05770
gene id: 361183:AMC99_RS05770
uniprot id: A0A0M3TA58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

361183:AMC99 RS01145
gene id: 361183:AMC99_RS01145
uniprot id: A0A0M4MTQ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-56 and Arg-59) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

361183:AMC99 RS07415
gene id: 361183:AMC99_RS07415
uniprot id: A0A0M3TAC6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

361183:AMC99 RS04530
gene id: 361183:AMC99_RS04530
uniprot id: A0A0M4LUF5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS03320
gene id: 361183:AMC99_RS03320
uniprot id: A0A0M5L4T9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

361183:AMC99 RS13545
gene id: 361183:AMC99_RS13545
uniprot id: A0A0M3TB75
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

361183:AMC99 RS13415
gene id: 361183:AMC99_RS13415
uniprot id: A0A0M5L3D4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.

361183:AMC99 RS11065
gene id: 361183:AMC99_RS11065
uniprot id: A0A0M3TAS2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS09320
gene id: 361183:AMC99_RS09320
uniprot id: A0A0M3TAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

361183:AMC99 RS08180
gene id: 361183:AMC99_RS08180
uniprot id: A0A0M4M4Y4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

361183:AMC99 RS07180
gene id: 361183:AMC99_RS07180
uniprot id: A0A0M4M848
names: Similarity
messages: Belongs to the virb1 family.

361183:AMC99 RS00015
gene id: 361183:AMC99_RS00015
uniprot id: A0A0M4MR04
names: Similarity
messages: Belongs to the ArsC family.

361183:AMC99 RS01035
gene id: 361183:AMC99_RS01035
uniprot id: A0A0M3T9S3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

361183:AMC99 RS08070
gene id: 361183:AMC99_RS08070
uniprot id: A0A0M3TAF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

361183:AMC99 RS03340
gene id: 361183:AMC99_RS03340
uniprot id: A0A0M4LTD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

361183:AMC99 RS06980
gene id: 361183:AMC99_RS06980
uniprot id: A0A0M3TAA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

361183:AMC99 RS11170
gene id: 361183:AMC99_RS11170
uniprot id: A0A0M3TAS6
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

361183:AMC99 RS01365
gene id: 361183:AMC99_RS01365
uniprot id: A0A0M3T9T8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

361183:AMC99 RS05570
gene id: 361183:AMC99_RS05570
uniprot id: A0A0M5L6S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

361183:AMC99 RS08970
gene id: 361183:AMC99_RS08970
uniprot id: A0A0M4M8T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

361183:AMC99 RS12395
gene id: 361183:AMC99_RS12395
uniprot id: A0A0M4M6F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS09535
gene id: 361183:AMC99_RS09535
uniprot id: A0A0M3TAK2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

361183:AMC99 RS07410
gene id: 361183:AMC99_RS07410
uniprot id: A0A0M5KYM2
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

361183:AMC99 RS08130
gene id: 361183:AMC99_RS08130
uniprot id: A0A0M4MHE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

361183:AMC99 RS03865
gene id: 361183:AMC99_RS03865
uniprot id: A0A0M4M6X0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

361183:AMC99 RS03150
gene id: 361183:AMC99_RS03150
uniprot id: A0A0M3TA11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

361183:AMC99 RS12300
gene id: 361183:AMC99_RS12300
uniprot id: A0A0M3TB35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

361183:AMC99 RS12805
gene id: 361183:AMC99_RS12805
uniprot id: A0A0M4LXF9
names: Similarity
messages: Belongs to the PhzF family.

361183:AMC99 RS04700
gene id: 361183:AMC99_RS04700
uniprot id: A0A0M4MG20
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

361183:AMC99 RS13285
gene id: 361183:AMC99_RS13285
uniprot id: A0A0M4MJF5
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS05435
gene id: 361183:AMC99_RS05435
uniprot id: A0A0M4LU46
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS12100
gene id: 361183:AMC99_RS12100
uniprot id: A0A0M3TB28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

361183:AMC99 RS00440
gene id: 361183:AMC99_RS00440
uniprot id: A0A0M4LSB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

361183:AMC99 RS02625
gene id: 361183:AMC99_RS02625
uniprot id: A0A0M5KZ41
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

361183:AMC99 RS12870
gene id: 361183:AMC99_RS12870
uniprot id: A0A0M4MA97
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

361183:AMC99 RS07990
gene id: 361183:AMC99_RS07990
uniprot id: A0A0M3TAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

361183:AMC99 RS05360
gene id: 361183:AMC99_RS05360
uniprot id: A0A0M4MV87
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

361183:AMC99 RS10600
gene id: 361183:AMC99_RS10600
uniprot id: A0A0M4M9F3
names: Similarity
messages: Belongs to the extradiol ring-cleavage dioxygenase family.

361183:AMC99 RS02985
gene id: 361183:AMC99_RS02985
uniprot id: A0A0M3T9U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

361183:AMC99 RS04935
gene id: 361183:AMC99_RS04935
uniprot id: A0A0M4M3U5
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

361183:AMC99 RS00920
gene id: 361183:AMC99_RS00920
uniprot id: A0A0M3T9L4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

361183:AMC99 RS01395
gene id: 361183:AMC99_RS01395
uniprot id: A0A0M3T9N4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

361183:AMC99 RS10670
gene id: 361183:AMC99_RS10670
uniprot id: A0A0M3TAW8
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS08720
gene id: 361183:AMC99_RS08720
uniprot id: A0A0M4M554
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

361183:AMC99 RS10485
gene id: 361183:AMC99_RS10485
uniprot id: A0A0M4LW05
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

361183:AMC99 RS01235
gene id: 361183:AMC99_RS01235
uniprot id: A0A0M4MER4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

361183:AMC99 RS12205
gene id: 361183:AMC99_RS12205
uniprot id: A0A0M4MA40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

361183:AMC99 RS03375
gene id: 361183:AMC99_RS03375
uniprot id: A0A0M4M6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

361183:AMC99 RS11430
gene id: 361183:AMC99_RS11430
uniprot id: A0A0M4MIM2
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

361183:AMC99 RS09285
gene id: 361183:AMC99_RS09285
uniprot id: A0A0M4M8X6
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS12380
gene id: 361183:AMC99_RS12380
uniprot id: A0A0M3TAW9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS07910
gene id: 361183:AMC99_RS07910
uniprot id: A0A0M4M8E4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

361183:AMC99 RS07665
gene id: 361183:AMC99_RS07665
uniprot id: A0A0M3TAD6
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS07045
gene id: 361183:AMC99_RS07045
uniprot id: A0A0M3TAH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

361183:AMC99 RS07750
gene id: 361183:AMC99_RS07750
uniprot id: A0A0M4LV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

361183:AMC99 RS11645
gene id: 361183:AMC99_RS11645
uniprot id: A0A0M3TAU4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

361183:AMC99 RS01125
gene id: 361183:AMC99_RS01125
uniprot id: A0A0M3T9S7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

361183:AMC99 RS10160
gene id: 361183:AMC99_RS10160
uniprot id: A0A0M5L798
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS08535
gene id: 361183:AMC99_RS08535
uniprot id: A0A0M4M8M6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

361183:AMC99 RS01445
gene id: 361183:AMC99_RS01445
uniprot id: A0A0M3T9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

361183:AMC99 RS09420
gene id: 361183:AMC99_RS09420
uniprot id: A0A0M4LVL9
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS08735
gene id: 361183:AMC99_RS08735
uniprot id: A0A0M5L2V5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS05685
gene id: 361183:AMC99_RS05685
uniprot id: A0A0M4LU89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

361183:AMC99 RS09125
gene id: 361183:AMC99_RS09125
uniprot id: A0A0M3TAQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS05335
gene id: 361183:AMC99_RS05335
uniprot id: A0A0M4MT29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

361183:AMC99 RS08890
gene id: 361183:AMC99_RS08890
uniprot id: A0A0M4LVZ8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

361183:AMC99 RS04685
gene id: 361183:AMC99_RS04685
uniprot id: A0A0M4M3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

361183:AMC99 RS05175
gene id: 361183:AMC99_RS05175
uniprot id: A0A0M4M3X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

361183:AMC99 RS12670
gene id: 361183:AMC99_RS12670
uniprot id: A0A0M4MVT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

361183:AMC99 RS05045
gene id: 361183:AMC99_RS05045
uniprot id: A0A0M4M7A5
names: Similarity
messages: Belongs to the peptidase S33 family.

361183:AMC99 RS07030
gene id: 361183:AMC99_RS07030
uniprot id: A0A0M4MTR2
names: Similarity
messages: Belongs to the TrpF family.

361183:AMC99 RS06495
gene id: 361183:AMC99_RS06495
uniprot id: A0A0M4M7V2
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

361183:AMC99 RS07770
gene id: 361183:AMC99_RS07770
uniprot id: A0A0M4MU04
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

361183:AMC99 RS07895
gene id: 361183:AMC99_RS07895
uniprot id: A0A0M5KYP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

361183:AMC99 RS08300
gene id: 361183:AMC99_RS08300
uniprot id: A0A0M4LV76
names: Similarity
messages: Belongs to the sterol desaturase family.

361183:AMC99 RS12445
gene id: 361183:AMC99_RS12445
uniprot id: A0A0M4MXV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

361183:AMC99 RS02120
gene id: 361183:AMC99_RS02120
uniprot id: A0A0M4LTJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

361183:AMC99 RS13010
gene id: 361183:AMC99_RS13010
uniprot id: A0A0M4MAE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS07945
gene id: 361183:AMC99_RS07945
uniprot id: A0A0M4LV29
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

361183:AMC99 RS06275
gene id: 361183:AMC99_RS06275
uniprot id: A0A0M3TA79
names: Similarity
messages: Belongs to the pirin family.

361183:AMC99 RS13435
gene id: 361183:AMC99_RS13435
uniprot id: A0A0M4MAH9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

361183:AMC99 RS01485
gene id: 361183:AMC99_RS01485
uniprot id: A0A0M5L6H9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

361183:AMC99 RS00085
gene id: 361183:AMC99_RS00085
uniprot id: A0A0M4LSV8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

361183:AMC99 RS07255
gene id: 361183:AMC99_RS07255
uniprot id: A0A0M4LUU7
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

361183:AMC99 RS13635
gene id: 361183:AMC99_RS13635
uniprot id: A0A0M4MAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

361183:AMC99 RS05980
gene id: 361183:AMC99_RS05980
uniprot id: A0A0M4M7Q2
names: Similarity
messages: Belongs to the TrpC family.

361183:AMC99 RS04740
gene id: 361183:AMC99_RS04740
uniprot id: A0A0M3TA74
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

361183:AMC99 RS11675
gene id: 361183:AMC99_RS11675
uniprot id: A0A0M4MIR1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

361183:AMC99 RS01060
gene id: 361183:AMC99_RS01060
uniprot id: A0A0M5KY16
names: Similarity
messages: Belongs to the serpin family.

361183:AMC99 RS03535
gene id: 361183:AMC99_RS03535
uniprot id: A0A0M5KY97
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

361183:AMC99 RS06285
gene id: 361183:AMC99_RS06285
uniprot id: A0A0M4LV35
names: Similarity
messages: Belongs to the asparagine synthetase family.

361183:AMC99 RS08325
gene id: 361183:AMC99_RS08325
uniprot id: A0A0M4LVS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

361183:AMC99 RS02750
gene id: 361183:AMC99_RS02750
uniprot id: A0A0M4MUA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

361183:AMC99 RS04085
gene id: 361183:AMC99_RS04085
uniprot id: A0A0M4MFU7
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS00645
gene id: 361183:AMC99_RS00645
uniprot id: A0A0M5L6C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

361183:AMC99 RS13310
gene id: 361183:AMC99_RS13310
uniprot id: A0A0M4LXM0
names: Similarity
messages: Belongs to the peptidase C40 family.

361183:AMC99 RS02735
gene id: 361183:AMC99_RS02735
uniprot id: A0A0M3T9T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

361183:AMC99 RS03650
gene id: 361183:AMC99_RS03650
uniprot id: A0A0M4M397
names: Similarity
messages: Belongs to the sodium:galactoside symporter (TC 2.A.2) family.

361183:AMC99 RS13120
gene id: 361183:AMC99_RS13120
uniprot id: A0A0M4MAD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

361183:AMC99 RS05585
gene id: 361183:AMC99_RS05585
uniprot id: A0A0M4LUU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

361183:AMC99 RS07740
gene id: 361183:AMC99_RS07740
uniprot id: A0A0M4M8B7
names: Similarity
messages: Belongs to the RecO family.

361183:AMC99 RS01710
gene id: 361183:AMC99_RS01710
uniprot id: A0A0M4MTX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

361183:AMC99 RS09630
gene id: 361183:AMC99_RS09630
uniprot id: A0A0M5KYU0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

361183:AMC99 RS07355
gene id: 361183:AMC99_RS07355
uniprot id: A0A0M5L571
names: Function
names: Subunit
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

361183:AMC99 RS02140
gene id: 361183:AMC99_RS02140
uniprot id: A0A0M4M653
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

361183:AMC99 RS05655
gene id: 361183:AMC99_RS05655
uniprot id: A0A0M5KYG8
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS13640
gene id: 361183:AMC99_RS13640
uniprot id: A0A0M4M6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

361183:AMC99 RS04130
gene id: 361183:AMC99_RS04130
uniprot id: A0A0M4LTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

361183:AMC99 RS04580
gene id: 361183:AMC99_RS04580
uniprot id: A0A0M5L6S5
names: Function
names: Subcellular Location Annotation
messages: Could be a virulence factor.
messages: Secreted

361183:AMC99 RS01670
gene id: 361183:AMC99_RS01670
uniprot id: A0A0M4MEW8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS11335
gene id: 361183:AMC99_RS11335
uniprot id: A0A0M5KZY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

361183:AMC99 RS06055
gene id: 361183:AMC99_RS06055
uniprot id: A0A0M4MVI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS05330
gene id: 361183:AMC99_RS05330
uniprot id: A0A0M5L2J7
names: Similarity
messages: Belongs to the MreC family.

361183:AMC99 RS05215
gene id: 361183:AMC99_RS05215
uniprot id: A0A0M4M7F1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

361183:AMC99 RS04645
gene id: 361183:AMC99_RS04645
uniprot id: A0A0M5L6P2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

361183:AMC99 RS09135
gene id: 361183:AMC99_RS09135
uniprot id: A0A0M4MUH4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS06915
gene id: 361183:AMC99_RS06915
uniprot id: A0A0M4LVA6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

361183:AMC99 RS06100
gene id: 361183:AMC99_RS06100
uniprot id: A0A0M4LV12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS12995
gene id: 361183:AMC99_RS12995
uniprot id: A0A0M3TB58
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

361183:AMC99 RS02380
gene id: 361183:AMC99_RS02380
uniprot id: A0A0M5L4Q9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

361183:AMC99 RS12105
gene id: 361183:AMC99_RS12105
uniprot id: A0A0M4MIX2
names: Similarity
messages: Belongs to the GARS family.

361183:AMC99 RS08340
gene id: 361183:AMC99_RS08340
uniprot id: A0A0M4MWA7
names: Similarity
messages: Belongs to the BolA/IbaG family.

361183:AMC99 RS00650
gene id: 361183:AMC99_RS00650
uniprot id: A0A0M4MR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS04770
gene id: 361183:AMC99_RS04770
uniprot id: A0A0M5KYD7
names: Similarity
messages: Belongs to the transketolase family.

361183:AMC99 RS05295
gene id: 361183:AMC99_RS05295
uniprot id: A0A0M4MV80
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

361183:AMC99 RS03345
gene id: 361183:AMC99_RS03345
uniprot id: A0A0M3T9W0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS02220
gene id: 361183:AMC99_RS02220
uniprot id: A0A0M4LSZ5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

361183:AMC99 RS07730
gene id: 361183:AMC99_RS07730
uniprot id: A0A0M4MW34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

361183:AMC99 RS05990
gene id: 361183:AMC99_RS05990
uniprot id: A0A0M4MVH7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

361183:AMC99 RS12985
gene id: 361183:AMC99_RS12985
uniprot id: A0A0M4LXI3
names: Similarity
messages: Belongs to the peptidase M1 family.

361183:AMC99 RS12515
gene id: 361183:AMC99_RS12515
uniprot id: A0A0M4MA75
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

361183:AMC99 RS11275
gene id: 361183:AMC99_RS11275
uniprot id: A0A0M3TAZ3
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

361183:AMC99 RS02330
gene id: 361183:AMC99_RS02330
uniprot id: A0A0M4M681
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

361183:AMC99 RS06260
gene id: 361183:AMC99_RS06260
uniprot id: A0A0M4LUG5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

361183:AMC99 RS00765
gene id: 361183:AMC99_RS00765
uniprot id: A0A0M5KY08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS11745
gene id: 361183:AMC99_RS11745
uniprot id: A0A0M4MVG1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS13730
gene id: 361183:AMC99_RS13730
uniprot id: A0A0M4MAM0
names: Similarity
messages: Belongs to the pyruvate kinase family.

361183:AMC99 RS13460
gene id: 361183:AMC99_RS13460
uniprot id: A0A0M4M6S6
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS06010
gene id: 361183:AMC99_RS06010
uniprot id: A0A0M4LUC8
names: Similarity
messages: Belongs to the citrate synthase family.

361183:AMC99 RS09120
gene id: 361183:AMC99_RS09120
uniprot id: A0A0M4MHR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

361183:AMC99 RS01180
gene id: 361183:AMC99_RS01180
uniprot id: A0A0M5L6G2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

361183:AMC99 RS03460
gene id: 361183:AMC99_RS03460
uniprot id: A0A0M4M375
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

361183:AMC99 RS12760
gene id: 361183:AMC99_RS12760
uniprot id: A0A0M4MXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

361183:AMC99 RS05125
gene id: 361183:AMC99_RS05125
uniprot id: A0A0M4MGA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

361183:AMC99 RS06070
gene id: 361183:AMC99_RS06070
uniprot id: A0A0M4LUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

361183:AMC99 RS08060
gene id: 361183:AMC99_RS08060
uniprot id: A0A0M4M4X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

361183:AMC99 RS11115
gene id: 361183:AMC99_RS11115
uniprot id: A0A0M4M9M8
names: Similarity
messages: Belongs to the YggT family.

361183:AMC99 RS05365
gene id: 361183:AMC99_RS05365
uniprot id: A0A0M4M7F0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

361183:AMC99 RS02040
gene id: 361183:AMC99_RS02040
uniprot id: A0A0M5KZY9
names: Similarity
messages: Belongs to the peptidase S8 family.

361183:AMC99 RS03355
gene id: 361183:AMC99_RS03355
uniprot id: A0A0M5L6N9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

361183:AMC99 RS01625
gene id: 361183:AMC99_RS01625
uniprot id: A0A0M3T9U9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

361183:AMC99 RS01920
gene id: 361183:AMC99_RS01920
uniprot id: A0A0M4MF05
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

361183:AMC99 RS06120
gene id: 361183:AMC99_RS06120
uniprot id: A0A0M4M7R1
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

361183:AMC99 RS07025
gene id: 361183:AMC99_RS07025
uniprot id: A0A0M3TAB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

361183:AMC99 RS09370
gene id: 361183:AMC99_RS09370
uniprot id: A0A0M3TAR0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

361183:AMC99 RS04170
gene id: 361183:AMC99_RS04170
uniprot id: A0A0M5KZ94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

361183:AMC99 RS06130
gene id: 361183:AMC99_RS06130
uniprot id: A0A0M4M490
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

361183:AMC99 RS13105
gene id: 361183:AMC99_RS13105
uniprot id: A0A0M5L3C1
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

361183:AMC99 RS13230
gene id: 361183:AMC99_RS13230
uniprot id: A0A0M3TB02
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

361183:AMC99 RS06800
gene id: 361183:AMC99_RS06800
uniprot id: A0A0M3TAF7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

361183:AMC99 RS01795
gene id: 361183:AMC99_RS01795
uniprot id: A0A0M4LSU1
names: Similarity
messages: Belongs to the Dps family.

361183:AMC99 RS06855
gene id: 361183:AMC99_RS06855
uniprot id: A0A0M4LVA0
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

361183:AMC99 RS06290
gene id: 361183:AMC99_RS06290
uniprot id: A0A0M4M7V1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

361183:AMC99 RS09355
gene id: 361183:AMC99_RS09355
uniprot id: A0A0M4M5B7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

361183:AMC99 RS09345
gene id: 361183:AMC99_RS09345
uniprot id: A0A0M4M8Y4
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

361183:AMC99 RS01570
gene id: 361183:AMC99_RS01570
uniprot id: A0A0M5KY24
names: Subcellular Location Annotation
messages: Cytoplasm

361183:AMC99 RS12625
gene id: 361183:AMC99_RS12625
uniprot id: A0A0M5L5Q2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

361183:AMC99 RS10655
gene id: 361183:AMC99_RS10655
uniprot id: A0A0M4MX63
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

361183:AMC99 RS00760
gene id: 361183:AMC99_RS00760
uniprot id: A0A0M4MEJ8
names: Similarity
messages: Belongs to the HIBADH-related family.

361183:AMC99 RS07515
gene id: 361183:AMC99_RS07515
uniprot id: A0A0M3TAD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

361183:AMC99 RS06210
gene id: 361183:AMC99_RS06210
uniprot id: A0A0M5L6V1
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

361183:AMC99 RS00045
gene id: 361183:AMC99_RS00045
uniprot id: A0A0M3T9N3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

361183:AMC99 RS00175
gene id: 361183:AMC99_RS00175
uniprot id: A0A0M4M5E0
names: Similarity
messages: Belongs to the DprA/Smf family.

361183:AMC99 RS04435
gene id: 361183:AMC99_RS04435
uniprot id: A0A0M4M3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

361183:AMC99 RS00375
gene id: 361183:AMC99_RS00375
uniprot id: A0A0M3T9J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

361183:AMC99 RS09940
gene id: 361183:AMC99_RS09940
uniprot id: A0A0M4M959
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

361183:AMC99 RS00300
gene id: 361183:AMC99_RS00300
uniprot id: A0A0M4M5F6
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

361183:AMC99 RS12535
gene id: 361183:AMC99_RS12535
uniprot id: A0A0M4MJ25
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

361183:AMC99 RS13205
gene id: 361183:AMC99_RS13205
uniprot id: A0A0M4MAG5
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

361183:AMC99 RS04835
gene id: 361183:AMC99_RS04835
uniprot id: A0A0M5L079
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

361183:AMC99 RS08080
gene id: 361183:AMC99_RS08080
uniprot id: A0A0M5L715
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

361183:AMC99 RS09465
gene id: 361183:AMC99_RS09465
uniprot id: A0A0M4M5C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

361183:AMC99 RS03475
gene id: 361183:AMC99_RS03475
uniprot id: A0A0M4MFL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS04200
gene id: 361183:AMC99_RS04200
uniprot id: A0A0M4LTN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

361183:AMC99 RS07445
gene id: 361183:AMC99_RS07445
uniprot id: A0A0M4MH36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

361183:AMC99 RS04825
gene id: 361183:AMC99_RS04825
uniprot id: A0A0M3TA20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

361183:AMC99 RS09735
gene id: 361183:AMC99_RS09735
uniprot id: A0A0M3TAL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

361183:AMC99 RS08870
gene id: 361183:AMC99_RS08870
uniprot id: A0A0M3TAP0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

361183:AMC99 RS02775
gene id: 361183:AMC99_RS02775
uniprot id: A0A0M4MFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS01505
gene id: 361183:AMC99_RS01505
uniprot id: A0A0M4M632
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

361183:AMC99 RS01685
gene id: 361183:AMC99_RS01685
uniprot id: A0A0M4MRM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS10215
gene id: 361183:AMC99_RS10215
uniprot id: A0A0M5L780
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS11100
gene id: 361183:AMC99_RS11100
uniprot id: A0A0M4M9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS11920
gene id: 361183:AMC99_RS11920
uniprot id: A0A0M4MVJ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

361183:AMC99 RS01085
gene id: 361183:AMC99_RS01085
uniprot id: A0A0M4MTP3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

361183:AMC99 RS08215
gene id: 361183:AMC99_RS08215
uniprot id: A0A0M3TAF6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

361183:AMC99 RS13210
gene id: 361183:AMC99_RS13210
uniprot id: A0A0M4M6Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

361183:AMC99 RS03465
gene id: 361183:AMC99_RS03465
uniprot id: A0A0M3TA23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

361183:AMC99 RS07700
gene id: 361183:AMC99_RS07700
uniprot id: A0A0M5L721
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

361183:AMC99 RS09325
gene id: 361183:AMC99_RS09325
uniprot id: A0A0M4LW54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

361183:AMC99 RS00750
gene id: 361183:AMC99_RS00750
uniprot id: A0A0M3T9R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

361183:AMC99 RS11570
gene id: 361183:AMC99_RS11570
uniprot id: A0A0M4LWZ9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

361183:AMC99 RS03390
gene id: 361183:AMC99_RS03390
uniprot id: A0A0M4M6M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

361183:AMC99 RS13140
gene id: 361183:AMC99_RS13140
uniprot id: A0A0M4MAF6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

361183:AMC99 RS09435
gene id: 361183:AMC99_RS09435
uniprot id: A0A0M4LW69
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

361183:AMC99 RS11355
gene id: 361183:AMC99_RS11355
uniprot id: A0A0M4M619
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

361183:AMC99 RS04455
gene id: 361183:AMC99_RS04455
uniprot id: A0A0M4MSQ4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

361183:AMC99 RS11005
gene id: 361183:AMC99_RS11005
uniprot id: A0A0M4MIG4
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS07500
gene id: 361183:AMC99_RS07500
uniprot id: A0A0M4LUX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

361183:AMC99 RS12060
gene id: 361183:AMC99_RS12060
uniprot id: A0A0M4LX72
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

361183:AMC99 RS10710
gene id: 361183:AMC99_RS10710
uniprot id: A0A0M5KZW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

361183:AMC99 RS08125
gene id: 361183:AMC99_RS08125
uniprot id: A0A0M4LV52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

361183:AMC99 RS10210
gene id: 361183:AMC99_RS10210
uniprot id: A0A0M4MI58
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

361183:AMC99 RS10625
gene id: 361183:AMC99_RS10625
uniprot id: A0A0M3TAW6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS12750
gene id: 361183:AMC99_RS12750
uniprot id: A0A0M3TB52
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

361183:AMC99 RS11820
gene id: 361183:AMC99_RS11820
uniprot id: A0A0M4MXM3
names: Similarity
messages: Belongs to the cytochrome P450 family.

361183:AMC99 RS09110
gene id: 361183:AMC99_RS09110
uniprot id: A0A0M4M588
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS09150
gene id: 361183:AMC99_RS09150
uniprot id: A0A0M5KZQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

361183:AMC99 RS03385
gene id: 361183:AMC99_RS03385
uniprot id: A0A0M4MUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

361183:AMC99 RS03450
gene id: 361183:AMC99_RS03450
uniprot id: A0A0M4MUI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

361183:AMC99 RS06535
gene id: 361183:AMC99_RS06535
uniprot id: A0A0M4M7Y1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS13085
gene id: 361183:AMC99_RS13085
uniprot id: A0A0M4M6N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

361183:AMC99 RS07670
gene id: 361183:AMC99_RS07670
uniprot id: A0A0M4MW27
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS03085
gene id: 361183:AMC99_RS03085
uniprot id: A0A0M4MS64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

361183:AMC99 RS09085
gene id: 361183:AMC99_RS09085
uniprot id: A0A0M4M8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

361183:AMC99 RS04075
gene id: 361183:AMC99_RS04075
uniprot id: A0A0M4LTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS06620
gene id: 361183:AMC99_RS06620
uniprot id: A0A0M3TA93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

361183:AMC99 RS07365
gene id: 361183:AMC99_RS07365
uniprot id: A0A0M4M873
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

361183:AMC99 RS12180
gene id: 361183:AMC99_RS12180
uniprot id: A0A0M4LX89
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

361183:AMC99 RS06325
gene id: 361183:AMC99_RS06325
uniprot id: A0A0M3TA81
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS13420
gene id: 361183:AMC99_RS13420
uniprot id: A0A0M4MW25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

361183:AMC99 RS05040
gene id: 361183:AMC99_RS05040
uniprot id: A0A0M4MV50
names: Similarity
messages: Belongs to the thioesterase PaaI family.

361183:AMC99 RS01335
gene id: 361183:AMC99_RS01335
uniprot id: A0A0M4M5U1
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

361183:AMC99 RS10910
gene id: 361183:AMC99_RS10910
uniprot id: A0A0M3TAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

361183:AMC99 RS10615
gene id: 361183:AMC99_RS10615
uniprot id: A0A0M4LW24
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

361183:AMC99 RS09930
gene id: 361183:AMC99_RS09930
uniprot id: A0A0M4LWD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

361183:AMC99 RS07290
gene id: 361183:AMC99_RS07290
uniprot id: A0A0M3TAI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

361183:AMC99 RS02890
gene id: 361183:AMC99_RS02890
uniprot id: A0A0M4M306
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

361183:AMC99 RS05240
gene id: 361183:AMC99_RS05240
uniprot id: A0A0M4M7D4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS04525
gene id: 361183:AMC99_RS04525
uniprot id: A0A0M4MSR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

361183:AMC99 RS07525
gene id: 361183:AMC99_RS07525
uniprot id: A0A0M4LVI3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

361183:AMC99 RS00950
gene id: 361183:AMC99_RS00950
uniprot id: A0A0M4LT55
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS03435
gene id: 361183:AMC99_RS03435
uniprot id: A0A0M4M6R6
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

361183:AMC99 RS01550
gene id: 361183:AMC99_RS01550
uniprot id: A0A0M4MRK8
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS10895
gene id: 361183:AMC99_RS10895
uniprot id: A0A0M4MV54
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

361183:AMC99 RS09845
gene id: 361183:AMC99_RS09845
uniprot id: A0A0M4MI10
names: Similarity
messages: Belongs to the peptidase S49 family.

361183:AMC99 RS05245
gene id: 361183:AMC99_RS05245
uniprot id: A0A0M4M3Y0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

361183:AMC99 RS11600
gene id: 361183:AMC99_RS11600
uniprot id: A0A0M4M650
names: Similarity
messages: Belongs to the glutamate synthase family.

361183:AMC99 RS12080
gene id: 361183:AMC99_RS12080
uniprot id: A0A0M4MA25
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

361183:AMC99 RS09215
gene id: 361183:AMC99_RS09215
uniprot id: A0A0M5L5C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

361183:AMC99 RS08745
gene id: 361183:AMC99_RS08745
uniprot id: A0A0M4MUD1
names: Similarity
messages: Belongs to the asparaginase 1 family.

361183:AMC99 RS09055
gene id: 361183:AMC99_RS09055
uniprot id: A0A0M3TAI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

361183:AMC99 RS10715
gene id: 361183:AMC99_RS10715
uniprot id: A0A0M4MX70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

361183:AMC99 RS00670
gene id: 361183:AMC99_RS00670
uniprot id: A0A0M5KXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

361183:AMC99 RS09750
gene id: 361183:AMC99_RS09750
uniprot id: A0A0M4M933
names: Similarity
messages: Belongs to the Gfa family.

361183:AMC99 RS13480
gene id: 361183:AMC99_RS13480
uniprot id: A0A0M4MW33
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

361183:AMC99 RS06695
gene id: 361183:AMC99_RS06695
uniprot id: A0A0M4M4G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

361183:AMC99 RS05795
gene id: 361183:AMC99_RS05795
uniprot id: A0A0M5L517
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

361183:AMC99 RS08370
gene id: 361183:AMC99_RS08370
uniprot id: A0A0M4MHH7
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

361183:AMC99 RS10945
gene id: 361183:AMC99_RS10945
uniprot id: A0A0M5L333
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

361183:AMC99 RS12705
gene id: 361183:AMC99_RS12705
uniprot id: A0A0M4MA98
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

361183:AMC99 RS04545
gene id: 361183:AMC99_RS04545
uniprot id: A0A0M4MUY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

361183:AMC99 RS06645
gene id: 361183:AMC99_RS06645
uniprot id: A0A0M5KYK0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

361183:AMC99 RS06420
gene id: 361183:AMC99_RS06420
uniprot id: A0A0M3TA85
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS09770
gene id: 361183:AMC99_RS09770
uniprot id: A0A0M4M5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

361183:AMC99 RS04635
gene id: 361183:AMC99_RS04635
uniprot id: A0A0M4MG10
names: Similarity
messages: Belongs to the thioredoxin family.

361183:AMC99 RS12070
gene id: 361183:AMC99_RS12070
uniprot id: A0A0M5KZ27
names: Similarity
messages: Belongs to the RNase T2 family.

361183:AMC99 RS05645
gene id: 361183:AMC99_RS05645
uniprot id: A0A0M4LUW0
names: Subcellular Location Annotation
messages: Membrane

361183:AMC99 RS11305
gene id: 361183:AMC99_RS11305
uniprot id: A0A0M4MIK5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

361183:AMC99 RS01755
gene id: 361183:AMC99_RS01755
uniprot id: A0A0M3T9P8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

361183:AMC99 RS07530
gene id: 361183:AMC99_RS07530
uniprot id: A0A0M4M8A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

361183:AMC99 RS03175
gene id: 361183:AMC99_RS03175
uniprot id: A0A0M4M6N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

361183:AMC99 RS10925
gene id: 361183:AMC99_RS10925
uniprot id: A0A0M4M5W3
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflK subfamily.

361183:AMC99 RS10720
gene id: 361183:AMC99_RS10720
uniprot id: A0A0M4M9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

361183:AMC99 RS05545
gene id: 361183:AMC99_RS05545
uniprot id: A0A0M4M7H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

361183:AMC99 RS10620
gene id: 361183:AMC99_RS10620
uniprot id: A0A0M4MIB3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

361183:AMC99 RS06955
gene id: 361183:AMC99_RS06955
uniprot id: A0A0M4LUQ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

361183:AMC99 RS02835
gene id: 361183:AMC99_RS02835
uniprot id: A0A0M3T9U0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

361183:AMC99 RS03680
gene id: 361183:AMC99_RS03680
uniprot id: A0A0M4M6V0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

361183:AMC99 RS08430
gene id: 361183:AMC99_RS08430
uniprot id: A0A0M4LV91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

361183:AMC99 RS02580
gene id: 361183:AMC99_RS02580
uniprot id: A0A0M4M2X1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

361183:AMC99 RS13565
gene id: 361183:AMC99_RS13565
uniprot id: A0A0M4MY80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS05450
gene id: 361183:AMC99_RS05450
uniprot id: A0A0M4MT50
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

361183:AMC99 RS07735
gene id: 361183:AMC99_RS07735
uniprot id: A0A0M3TAK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS02575
gene id: 361183:AMC99_RS02575
uniprot id: A0A0M4M6B3
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

361183:AMC99 RS05765
gene id: 361183:AMC99_RS05765
uniprot id: A0A0M5L0A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

361183:AMC99 RS13145
gene id: 361183:AMC99_RS13145
uniprot id: A0A0M4M6P3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

361183:AMC99 RS07545
gene id: 361183:AMC99_RS07545
uniprot id: A0A0M4MW15
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

361183:AMC99 RS01500
gene id: 361183:AMC99_RS01500
uniprot id: A0A0M3T9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

361183:AMC99 RS08595
gene id: 361183:AMC99_RS08595
uniprot id: A0A0M3TAG5
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

361183:AMC99 RS01275
gene id: 361183:AMC99_RS01275
uniprot id: A0A0M4M5T5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

361183:AMC99 RS12580
gene id: 361183:AMC99_RS12580
uniprot id: A0A0M3TAX7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

361183:AMC99 RS08035
gene id: 361183:AMC99_RS08035
uniprot id: A0A0M4M8G0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

361183:AMC99 RS05975
gene id: 361183:AMC99_RS05975
uniprot id: A0A0M3TA66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

361183:AMC99 RS07465
gene id: 361183:AMC99_RS07465
uniprot id: A0A0M3TAC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

361183:AMC99 RS03270
gene id: 361183:AMC99_RS03270
uniprot id: A0A0M4M354
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

361183:AMC99 RS02530
gene id: 361183:AMC99_RS02530
uniprot id: A0A0M4LT34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.