351671:XDD1 RS01570
gene id: 351671:XDD1_RS01570
uniprot id: A0A068QN96
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

351671:XDD1 RS05465
gene id: 351671:XDD1_RS05465
uniprot id: A0A068QPC7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351671:XDD1 RS15780
gene id: 351671:XDD1_RS15780
uniprot id: A0A068QVS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

351671:XDD1 RS04080
gene id: 351671:XDD1_RS04080
uniprot id: A0A068QP54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

351671:XDD1 RS07130
gene id: 351671:XDD1_RS07130
uniprot id: A0A068QRL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

351671:XDD1 RS16065
gene id: 351671:XDD1_RS16065
uniprot id: A0A068QZB3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

351671:XDD1 RS05390
gene id: 351671:XDD1_RS05390
uniprot id: A0A068QQF1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS15555
gene id: 351671:XDD1_RS15555
uniprot id: A0A068QWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS01490
gene id: 351671:XDD1_RS01490
uniprot id: A0A068QMU6
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

351671:XDD1 RS13020
gene id: 351671:XDD1_RS13020
uniprot id: A0A068QUP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

351671:XDD1 RS06400
gene id: 351671:XDD1_RS06400
uniprot id: A0A068QQI4
names: Function
names: Similarity
messages: Belongs to the cycloisomerase 2 family.
messages: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

351671:XDD1 RS08520
gene id: 351671:XDD1_RS08520
uniprot id: A0A068QR60
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

351671:XDD1 RS08595
gene id: 351671:XDD1_RS08595
uniprot id: A0A068QR80
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

351671:XDD1 RS08035
gene id: 351671:XDD1_RS08035
uniprot id: A0A068QS11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

351671:XDD1 RS03495
gene id: 351671:XDD1_RS03495
uniprot id: A0A068QRJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

351671:XDD1 RS10940
gene id: 351671:XDD1_RS10940
uniprot id: A0A068QTU2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

351671:XDD1 RS17060
gene id: 351671:XDD1_RS17060
uniprot id: A0A068QWN1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS10835
gene id: 351671:XDD1_RS10835
uniprot id: A0A068QSQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

351671:XDD1 RS13870
gene id: 351671:XDD1_RS13870
uniprot id: A0A068QUM2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06105
gene id: 351671:XDD1_RS06105
uniprot id: A0A068QPT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

351671:XDD1 RS04085
gene id: 351671:XDD1_RS04085
uniprot id: A0A068QRV9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

351671:XDD1 RS10565
gene id: 351671:XDD1_RS10565
uniprot id: A0A068QVT8
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

351671:XDD1 RS03920
gene id: 351671:XDD1_RS03920
uniprot id: A0A068QNM2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

351671:XDD1 RS07210
gene id: 351671:XDD1_RS07210
uniprot id: A0A068QR75
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

351671:XDD1 RS16090
gene id: 351671:XDD1_RS16090
uniprot id: A0A068QWZ1
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

351671:XDD1 RS08005
gene id: 351671:XDD1_RS08005
uniprot id: A0A068QRL1
names: Similarity
messages: Belongs to the UPF0181 family.

351671:XDD1 RS03005
gene id: 351671:XDD1_RS03005
uniprot id: A0A068QNM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

351671:XDD1 RS09680
gene id: 351671:XDD1_RS09680
uniprot id: A0A068QVC9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351671:XDD1 RS15145
gene id: 351671:XDD1_RS15145
uniprot id: A0A068QYQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

351671:XDD1 RS05605
gene id: 351671:XDD1_RS05605
uniprot id: A0A068QPE7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS15215
gene id: 351671:XDD1_RS15215
uniprot id: A0A068QYR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

351671:XDD1 RS10190
gene id: 351671:XDD1_RS10190
uniprot id: A0A068QSE0
names: Similarity
messages: Belongs to the peptidase S49 family.

351671:XDD1 RS03915
gene id: 351671:XDD1_RS03915
uniprot id: A0A068QNG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

351671:XDD1 RS03535
gene id: 351671:XDD1_RS03535
uniprot id: A0A068QNF8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

351671:XDD1 RS14135
gene id: 351671:XDD1_RS14135
uniprot id: A0A068QY82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

351671:XDD1 RS13785
gene id: 351671:XDD1_RS13785
uniprot id: A0A068QVL5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

351671:XDD1 RS05725
gene id: 351671:XDD1_RS05725
uniprot id: A0A068QSW9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

351671:XDD1 RS13950
gene id: 351671:XDD1_RS13950
uniprot id: A0A068QUP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

351671:XDD1 RS14500
gene id: 351671:XDD1_RS14500
uniprot id: A0A068QVN8
names: Function
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.
messages: Catalyzes the formation of putrescine from agmatine.

351671:XDD1 RS07435
gene id: 351671:XDD1_RS07435
uniprot id: A0A068QQS9
names: Caution
names: Function
names: Induction
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the SulA family.
messages: By DNA damage, as part of the SOS response.
messages: Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
messages: Interacts with FtsZ.
messages: Is rapidly cleaved and degraded by the Lon protease once DNA damage is repaired.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS10005
gene id: 351671:XDD1_RS10005
uniprot id: A0A068QSV7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

351671:XDD1 RS12430
gene id: 351671:XDD1_RS12430
uniprot id: A0A068QTS7
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

351671:XDD1 RS14750
gene id: 351671:XDD1_RS14750
uniprot id: A0A068QVS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

351671:XDD1 RS10650
gene id: 351671:XDD1_RS10650
uniprot id: A0A068QSN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Flagellar protein that affects chemotactic events.
messages: Membrane

351671:XDD1 RS07170
gene id: 351671:XDD1_RS07170
uniprot id: A0A068QTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

351671:XDD1 RS10105
gene id: 351671:XDD1_RS10105
uniprot id: A0A068QSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

351671:XDD1 RS00970
gene id: 351671:XDD1_RS00970
uniprot id: A0A068QM45
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

351671:XDD1 RS04010
gene id: 351671:XDD1_RS04010
uniprot id: A0A068QNN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS16790
gene id: 351671:XDD1_RS16790
uniprot id: A0A068QWD8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

351671:XDD1 RS15660
gene id: 351671:XDD1_RS15660
uniprot id: A0A068QVT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

351671:XDD1 RS02625
gene id: 351671:XDD1_RS02625
uniprot id: A0A068QMX6
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351671:XDD1 RS02335
gene id: 351671:XDD1_RS02335
uniprot id: A0A068QQU9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS11710
gene id: 351671:XDD1_RS11710
uniprot id: A0A068QWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

351671:XDD1 RS14570
gene id: 351671:XDD1_RS14570
uniprot id: A0A068QV27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

351671:XDD1 RS00370
gene id: 351671:XDD1_RS00370
uniprot id: A0A068QMR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS00500
gene id: 351671:XDD1_RS00500
uniprot id: A0A068QM37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein B family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS11785
gene id: 351671:XDD1_RS11785
uniprot id: A0A068QUH2
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

351671:XDD1 RS16120
gene id: 351671:XDD1_RS16120
uniprot id: A0A068QVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

351671:XDD1 RS07090
gene id: 351671:XDD1_RS07090
uniprot id: A0A068QQF6
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS12920
gene id: 351671:XDD1_RS12920
uniprot id: A0A068QUM5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

351671:XDD1 RS00090
gene id: 351671:XDD1_RS00090
uniprot id: A0A068QLZ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351671:XDD1 RS01465
gene id: 351671:XDD1_RS01465
uniprot id: A0A068QMU3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

351671:XDD1 RS01900
gene id: 351671:XDD1_RS01900
uniprot id: A0A068QQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

351671:XDD1 RS02230
gene id: 351671:XDD1_RS02230
uniprot id: A0A068QQS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

351671:XDD1 RS06280
gene id: 351671:XDD1_RS06280
uniprot id: A0A068QT70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS13630
gene id: 351671:XDD1_RS13630
uniprot id: A0A068QUI4
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

351671:XDD1 RS16785
gene id: 351671:XDD1_RS16785
uniprot id: A0A068QXF3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

351671:XDD1 RS09935
gene id: 351671:XDD1_RS09935
uniprot id: A0A068QS98
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS05960
gene id: 351671:XDD1_RS05960
uniprot id: A0A068QQQ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

351671:XDD1 RS11030
gene id: 351671:XDD1_RS11030
uniprot id: A0A068QSX2
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

351671:XDD1 RS14715
gene id: 351671:XDD1_RS14715
uniprot id: A0A068QV47
names: Function
names: Similarity
names: Subunit
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).
messages: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.

351671:XDD1 RS13935
gene id: 351671:XDD1_RS13935
uniprot id: A0A068QVB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

351671:XDD1 RS07270
gene id: 351671:XDD1_RS07270
uniprot id: A0A068QQQ2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

351671:XDD1 RS12805
gene id: 351671:XDD1_RS12805
uniprot id: A0A068QUX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

351671:XDD1 RS14325
gene id: 351671:XDD1_RS14325
uniprot id: A0A068QUX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

351671:XDD1 RS16370
gene id: 351671:XDD1_RS16370
uniprot id: A0A068QZL4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351671:XDD1 RS17575
gene id: 351671:XDD1_RS17575
uniprot id: A0A068QWS6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
messages: Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.

351671:XDD1 RS00900
gene id: 351671:XDD1_RS00900
uniprot id: A0A068QM38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
messages: Cell inner membrane
messages: Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux.
messages: Homodimer.
messages: Membrane

351671:XDD1 RS16315
gene id: 351671:XDD1_RS16315
uniprot id: A0A068QWB1
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

351671:XDD1 RS10405
gene id: 351671:XDD1_RS10405
uniprot id: A0A068QSH3
names: Function
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.

351671:XDD1 RS06845
gene id: 351671:XDD1_RS06845
uniprot id: A0A068QRB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS03515
gene id: 351671:XDD1_RS03515
uniprot id: A0A068QNV1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS08855
gene id: 351671:XDD1_RS08855
uniprot id: A0A068QSI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS12245
gene id: 351671:XDD1_RS12245
uniprot id: A0A068QUP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS01290
gene id: 351671:XDD1_RS01290
uniprot id: A0A068QN51
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
messages: Belongs to the biotin--protein ligase family.

351671:XDD1 RS04625
gene id: 351671:XDD1_RS04625
uniprot id: A0A068QQ04
names: Cofactor
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.

351671:XDD1 RS12615
gene id: 351671:XDD1_RS12615
uniprot id: A0A068QUG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS05665
gene id: 351671:XDD1_RS05665
uniprot id: A0A068QSV9
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS08610
gene id: 351671:XDD1_RS08610
uniprot id: A0A068QUM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

351671:XDD1 RS01515
gene id: 351671:XDD1_RS01515
uniprot id: A0A068QQA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

351671:XDD1 RS06325
gene id: 351671:XDD1_RS06325
uniprot id: A0A068QT81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

351671:XDD1 RS04610
gene id: 351671:XDD1_RS04610
uniprot id: A0A068QS97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpB subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Proton-dependent permease that transports di- and tripeptides.

351671:XDD1 RS02030
gene id: 351671:XDD1_RS02030
uniprot id: A0A068QMJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

351671:XDD1 RS00425
gene id: 351671:XDD1_RS00425
uniprot id: A0A068QLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

351671:XDD1 RS10990
gene id: 351671:XDD1_RS10990
uniprot id: A0A068QSW2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

351671:XDD1 RS16545
gene id: 351671:XDD1_RS16545
uniprot id: A0A068QWZ4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

351671:XDD1 RS00525
gene id: 351671:XDD1_RS00525
uniprot id: A0A068QPS5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS16215
gene id: 351671:XDD1_RS16215
uniprot id: A0A068QW71
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

351671:XDD1 RS02040
gene id: 351671:XDD1_RS02040
uniprot id: A0A068QN44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

351671:XDD1 RS09505
gene id: 351671:XDD1_RS09505
uniprot id: A0A068QRY6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS07050
gene id: 351671:XDD1_RS07050
uniprot id: A0A068QQL3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

351671:XDD1 RS12120
gene id: 351671:XDD1_RS12120
uniprot id: A0A068QU87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

351671:XDD1 RS17445
gene id: 351671:XDD1_RS17445
uniprot id: A0A068R035
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

351671:XDD1 RS06555
gene id: 351671:XDD1_RS06555
uniprot id: A0A068QQ50
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS02380
gene id: 351671:XDD1_RS02380
uniprot id: A0A068QQW1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrI family.
messages: Binds 1 zinc ion per subunit.
messages: Contains catalytic and regulatory chains.
messages: Involved in allosteric regulation of aspartate carbamoyltransferase.

351671:XDD1 RS17345
gene id: 351671:XDD1_RS17345
uniprot id: A0A068QWM6
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS02900
gene id: 351671:XDD1_RS02900
uniprot id: A0A068QN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

351671:XDD1 RS09580
gene id: 351671:XDD1_RS09580
uniprot id: A0A068QS35
names: Similarity
messages: Belongs to the pyruvate kinase family.

351671:XDD1 RS03650
gene id: 351671:XDD1_RS03650
uniprot id: A0A068QNI0
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. GpmB subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS10150
gene id: 351671:XDD1_RS10150
uniprot id: A0A068QSD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

351671:XDD1 RS15030
gene id: 351671:XDD1_RS15030
uniprot id: A0A068QWB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

351671:XDD1 RS04690
gene id: 351671:XDD1_RS04690
uniprot id: A0A068QSC3
names: Function
names: Similarity
messages: Belongs to the non-flavoprotein flavin reductase family. HpaC subfamily.
messages: Catalyzes the reduction of free flavins (FMN, FAD and riboflavin) by NADH. Subsequently, the reduced flavins diffuse to the large HpaB component or to other electron acceptors such as cytochrome c and Fe(3+) ion.

351671:XDD1 RS16780
gene id: 351671:XDD1_RS16780
uniprot id: A0A068QX27
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

351671:XDD1 RS16760
gene id: 351671:XDD1_RS16760
uniprot id: A0A068QZR8
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS09280
gene id: 351671:XDD1_RS09280
uniprot id: A0A068QRP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

351671:XDD1 RS09575
gene id: 351671:XDD1_RS09575
uniprot id: A0A068QRZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
messages: Cell inner membrane

351671:XDD1 RS11500
gene id: 351671:XDD1_RS11500
uniprot id: A0A068QWE6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

351671:XDD1 RS10415
gene id: 351671:XDD1_RS10415
uniprot id: A0A068QVQ7
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

351671:XDD1 RS05480
gene id: 351671:XDD1_RS05480
uniprot id: A0A068QSS7
names: Function
names: Similarity
messages: Belongs to the GMC oxidoreductase family.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.

351671:XDD1 RS14890
gene id: 351671:XDD1_RS14890
uniprot id: A0A068QYL1
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

351671:XDD1 RS13740
gene id: 351671:XDD1_RS13740
uniprot id: A0A068QVK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

351671:XDD1 RS01285
gene id: 351671:XDD1_RS01285
uniprot id: A0A068QQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

351671:XDD1 RS03785
gene id: 351671:XDD1_RS03785
uniprot id: A0A068QRP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

351671:XDD1 RS13880
gene id: 351671:XDD1_RS13880
uniprot id: A0A068QVA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

351671:XDD1 RS01830
gene id: 351671:XDD1_RS01830
uniprot id: A0A068QMZ8
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

351671:XDD1 RS05795
gene id: 351671:XDD1_RS05795
uniprot id: A0A068QQL8
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS11645
gene id: 351671:XDD1_RS11645
uniprot id: A0A068QWP0
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

351671:XDD1 RS15195
gene id: 351671:XDD1_RS15195
uniprot id: A0A068QWD7
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS18535
gene id: 351671:XDD1_RS18535
uniprot id: A0A068QXI1
names: Similarity
messages: Belongs to the intimin/invasin family.

351671:XDD1 RS00010
gene id: 351671:XDD1_RS00010
uniprot id: A0A068QLX1
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS01810
gene id: 351671:XDD1_RS01810
uniprot id: A0A068QMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

351671:XDD1 RS10000
gene id: 351671:XDD1_RS10000
uniprot id: A0A068QSB2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01405
gene id: 351671:XDD1_RS01405
uniprot id: A0A068QMA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

351671:XDD1 RS11350
gene id: 351671:XDD1_RS11350
uniprot id: A0A068QT53
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS06070
gene id: 351671:XDD1_RS06070
uniprot id: A0A068QQS6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS17595
gene id: 351671:XDD1_RS17595
uniprot id: A0A068QXT7
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

351671:XDD1 RS01420
gene id: 351671:XDD1_RS01420
uniprot id: A0A068QQ88
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

351671:XDD1 RS01015
gene id: 351671:XDD1_RS01015
uniprot id: A0A068QMZ6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS05140
gene id: 351671:XDD1_RS05140
uniprot id: A0A068QP78
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS03455
gene id: 351671:XDD1_RS03455
uniprot id: A0A068QP81
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

351671:XDD1 RS16895
gene id: 351671:XDD1_RS16895
uniprot id: A0A068QWF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrH/TusB family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

351671:XDD1 RS10925
gene id: 351671:XDD1_RS10925
uniprot id: A0A068QSV0
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

351671:XDD1 RS01635
gene id: 351671:XDD1_RS01635
uniprot id: A0A068QMW6
names: Function
names: Similarity
messages: Belongs to the GppA/Ppx family. GppA subfamily.
messages: Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.

351671:XDD1 RS14185
gene id: 351671:XDD1_RS14185
uniprot id: A0A068QY89
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

351671:XDD1 RS04220
gene id: 351671:XDD1_RS04220
uniprot id: A0A068QNS6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351671:XDD1 RS07315
gene id: 351671:XDD1_RS07315
uniprot id: A0A068QQJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

351671:XDD1 RS02420
gene id: 351671:XDD1_RS02420
uniprot id: A0A068QNC8
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

351671:XDD1 RS14495
gene id: 351671:XDD1_RS14495
uniprot id: A0A068QV45
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

351671:XDD1 RS00600
gene id: 351671:XDD1_RS00600
uniprot id: A0A068QMU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

351671:XDD1 RS11465
gene id: 351671:XDD1_RS11465
uniprot id: A0A068QT57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

351671:XDD1 RS10370
gene id: 351671:XDD1_RS10370
uniprot id: A0A068QTG6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

351671:XDD1 RS10215
gene id: 351671:XDD1_RS10215
uniprot id: A0A068QSZ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

351671:XDD1 RS12435
gene id: 351671:XDD1_RS12435
uniprot id: A0A068QUD7
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

351671:XDD1 RS10055
gene id: 351671:XDD1_RS10055
uniprot id: A0A068QSW3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

351671:XDD1 RS05985
gene id: 351671:XDD1_RS05985
uniprot id: A0A068QT17
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

351671:XDD1 RS05425
gene id: 351671:XDD1_RS05425
uniprot id: A0A068QQ10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

351671:XDD1 RS15085
gene id: 351671:XDD1_RS15085
uniprot id: A0A068QVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

351671:XDD1 RS08990
gene id: 351671:XDD1_RS08990
uniprot id: A0A068QSL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

351671:XDD1 RS11490
gene id: 351671:XDD1_RS11490
uniprot id: A0A068QT88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LpoB family.
messages: Cell outer membrane
messages: Interacts with PBP1b.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).

351671:XDD1 RS09970
gene id: 351671:XDD1_RS09970
uniprot id: A0A068QS72
names: Similarity
messages: Belongs to the thioredoxin family.

351671:XDD1 RS07365
gene id: 351671:XDD1_RS07365
uniprot id: A0A068QQJ6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

351671:XDD1 RS05550
gene id: 351671:XDD1_RS05550
uniprot id: A0A068QPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
messages: In the N-terminal section; belongs to the 2-acyl-GPE acetyltransferase family.
messages: Plays a role in lysophospholipid acylation. Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.

351671:XDD1 RS00950
gene id: 351671:XDD1_RS00950
uniprot id: A0A068QM89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

351671:XDD1 RS03395
gene id: 351671:XDD1_RS03395
uniprot id: A0A068QNT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

351671:XDD1 RS14780
gene id: 351671:XDD1_RS14780
uniprot id: A0A068QYJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS01410
gene id: 351671:XDD1_RS01410
uniprot id: A0A068QME3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

351671:XDD1 RS01560
gene id: 351671:XDD1_RS01560
uniprot id: A0A068QMV3
names: Function
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.
messages: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.

351671:XDD1 RS13925
gene id: 351671:XDD1_RS13925
uniprot id: A0A068QUN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

351671:XDD1 RS17610
gene id: 351671:XDD1_RS17610
uniprot id: A0A068QXH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

351671:XDD1 RS02240
gene id: 351671:XDD1_RS02240
uniprot id: A0A068QMN1
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

351671:XDD1 RS01460
gene id: 351671:XDD1_RS01460
uniprot id: A0A068QMF2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

351671:XDD1 RS17790
gene id: 351671:XDD1_RS17790
uniprot id: A0A068QWX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions.

351671:XDD1 RS13400
gene id: 351671:XDD1_RS13400
uniprot id: A0A068QUA2
names: Similarity
messages: Belongs to the protease inhibitor I11 (ecotin) family.

351671:XDD1 RS06060
gene id: 351671:XDD1_RS06060
uniprot id: A0A068QQC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351671:XDD1 RS15285
gene id: 351671:XDD1_RS15285
uniprot id: A0A068QW32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

351671:XDD1 RS01075
gene id: 351671:XDD1_RS01075
uniprot id: A0A068QQ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

351671:XDD1 RS05595
gene id: 351671:XDD1_RS05595
uniprot id: A0A068QSU6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

351671:XDD1 RS01415
gene id: 351671:XDD1_RS01415
uniprot id: A0A068QMT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

351671:XDD1 RS08590
gene id: 351671:XDD1_RS08590
uniprot id: A0A068QSD1
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.

351671:XDD1 RS08185
gene id: 351671:XDD1_RS08185
uniprot id: A0A068QUD9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351671:XDD1 RS04120
gene id: 351671:XDD1_RS04120
uniprot id: A0A068QNQ8
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

351671:XDD1 RS16840
gene id: 351671:XDD1_RS16840
uniprot id: A0A068QXG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351671:XDD1 RS01295
gene id: 351671:XDD1_RS01295
uniprot id: A0A068QM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

351671:XDD1 RS09875
gene id: 351671:XDD1_RS09875
uniprot id: A0A068QST2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12345
gene id: 351671:XDD1_RS12345
uniprot id: A0A068QTR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

351671:XDD1 RS16845
gene id: 351671:XDD1_RS16845
uniprot id: A0A068QWE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

351671:XDD1 RS07955
gene id: 351671:XDD1_RS07955
uniprot id: A0A068QRK1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05845
gene id: 351671:XDD1_RS05845
uniprot id: A0A068QQ81
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS17430
gene id: 351671:XDD1_RS17430
uniprot id: A0A068QWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS02495
gene id: 351671:XDD1_RS02495
uniprot id: A0A068QMW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

351671:XDD1 RS05760
gene id: 351671:XDD1_RS05760
uniprot id: A0A068QPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351671:XDD1 RS12155
gene id: 351671:XDD1_RS12155
uniprot id: A0A068QTK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

351671:XDD1 RS01685
gene id: 351671:XDD1_RS01685
uniprot id: A0A068QQD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WecD family.
messages: Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS13885
gene id: 351671:XDD1_RS13885
uniprot id: A0A068QXY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

351671:XDD1 RS01395
gene id: 351671:XDD1_RS01395
uniprot id: A0A068QQ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

351671:XDD1 RS11545
gene id: 351671:XDD1_RS11545
uniprot id: A0A068QTU8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

351671:XDD1 RS07475
gene id: 351671:XDD1_RS07475
uniprot id: A0A068QQL4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

351671:XDD1 RS12875
gene id: 351671:XDD1_RS12875
uniprot id: A0A068QX95
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

351671:XDD1 RS03355
gene id: 351671:XDD1_RS03355
uniprot id: A0A068QP63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS04590
gene id: 351671:XDD1_RS04590
uniprot id: A0A068QPZ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
messages: Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS15295
gene id: 351671:XDD1_RS15295
uniprot id: A0A068QWG1
names: Similarity
messages: Belongs to the UPF0325 family.

351671:XDD1 RS11510
gene id: 351671:XDD1_RS11510
uniprot id: A0A068QT73
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

351671:XDD1 RS01430
gene id: 351671:XDD1_RS01430
uniprot id: A0A068QMA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351671:XDD1 RS00485
gene id: 351671:XDD1_RS00485
uniprot id: A0A068QPR7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS13840
gene id: 351671:XDD1_RS13840
uniprot id: A0A068QV90
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

351671:XDD1 RS07950
gene id: 351671:XDD1_RS07950
uniprot id: A0A068QR13
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01895
gene id: 351671:XDD1_RS01895
uniprot id: A0A068QN14
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS08630
gene id: 351671:XDD1_RS08630
uniprot id: A0A068QRX6
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

351671:XDD1 RS01700
gene id: 351671:XDD1_RS01700
uniprot id: A0A068QMI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 56 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
messages: Cell inner membrane

351671:XDD1 RS17855
gene id: 351671:XDD1_RS17855
uniprot id: A0A068QXM0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

351671:XDD1 RS06700
gene id: 351671:XDD1_RS06700
uniprot id: A0A068QTG4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.
messages: Homotetramer.

351671:XDD1 RS09070
gene id: 351671:XDD1_RS09070
uniprot id: A0A068QSP6
names: Similarity
messages: Belongs to the IucA/IucC family.

351671:XDD1 RS08825
gene id: 351671:XDD1_RS08825
uniprot id: A0A068QRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Membrane
messages: Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake.

351671:XDD1 RS02360
gene id: 351671:XDD1_RS02360
uniprot id: A0A068QQV5
names: Similarity
messages: Belongs to the UPF0306 family.

351671:XDD1 RS14735
gene id: 351671:XDD1_RS14735
uniprot id: A0A068QW61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. RfaH is recruited into a multi-component RNA polymerase complex by the ops element, which is a short conserved DNA sequence located downstream of the main promoter of these operons. Once bound, RfaH suppresses pausing and inhibits Rho-dependent and intrinsic termination at a subset of sites. Termination signals are bypassed, which allows complete synthesis of long RNA chains.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

351671:XDD1 RS06825
gene id: 351671:XDD1_RS06825
uniprot id: A0A068QQ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

351671:XDD1 RS11205
gene id: 351671:XDD1_RS11205
uniprot id: A0A068QT06
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

351671:XDD1 RS15360
gene id: 351671:XDD1_RS15360
uniprot id: A0A068QWH7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS02450
gene id: 351671:XDD1_RS02450
uniprot id: A0A068QMU2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

351671:XDD1 RS08195
gene id: 351671:XDD1_RS08195
uniprot id: A0A068QR01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

351671:XDD1 RS12150
gene id: 351671:XDD1_RS12150
uniprot id: A0A068QWW3
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

351671:XDD1 RS16125
gene id: 351671:XDD1_RS16125
uniprot id: A0A068QW49
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS07350
gene id: 351671:XDD1_RS07350
uniprot id: A0A068QRA0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

351671:XDD1 RS02145
gene id: 351671:XDD1_RS02145
uniprot id: A0A068QMR3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS09160
gene id: 351671:XDD1_RS09160
uniprot id: A0A068QRM1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS06065
gene id: 351671:XDD1_RS06065
uniprot id: A0A068QT27
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

351671:XDD1 RS03025
gene id: 351671:XDD1_RS03025
uniprot id: A0A068QN88
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

351671:XDD1 RS08040
gene id: 351671:XDD1_RS08040
uniprot id: A0A068QQX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

351671:XDD1 RS12510
gene id: 351671:XDD1_RS12510
uniprot id: A0A068QTR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

351671:XDD1 RS17605
gene id: 351671:XDD1_RS17605
uniprot id: A0A068QWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

351671:XDD1 RS00635
gene id: 351671:XDD1_RS00635
uniprot id: A0A068QMU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

351671:XDD1 RS00740
gene id: 351671:XDD1_RS00740
uniprot id: A0A068QM63
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

351671:XDD1 RS15160
gene id: 351671:XDD1_RS15160
uniprot id: A0A068QW07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS09220
gene id: 351671:XDD1_RS09220
uniprot id: A0A068QV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

351671:XDD1 RS18540
gene id: 351671:XDD1_RS18540
uniprot id: A0A068QXI6
names: Similarity
messages: Belongs to the intimin/invasin family.

351671:XDD1 RS00240
gene id: 351671:XDD1_RS00240
uniprot id: A0A068QM16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

351671:XDD1 RS10960
gene id: 351671:XDD1_RS10960
uniprot id: A0A068QW25
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS11035
gene id: 351671:XDD1_RS11035
uniprot id: A0A068QTG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

351671:XDD1 RS14055
gene id: 351671:XDD1_RS14055
uniprot id: A0A068QVG7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

351671:XDD1 RS06730
gene id: 351671:XDD1_RS06730
uniprot id: A0A068QR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

351671:XDD1 RS05570
gene id: 351671:XDD1_RS05570
uniprot id: A0A068QPI9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm
messages: Homotetramer.

351671:XDD1 RS08570
gene id: 351671:XDD1_RS08570
uniprot id: A0A068QSC6
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

351671:XDD1 RS12145
gene id: 351671:XDD1_RS12145
uniprot id: A0A068QU89
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12605
gene id: 351671:XDD1_RS12605
uniprot id: A0A068QTS9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

351671:XDD1 RS04145
gene id: 351671:XDD1_RS04145
uniprot id: A0A068QNR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS07230
gene id: 351671:XDD1_RS07230
uniprot id: A0A068QR79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

351671:XDD1 RS05365
gene id: 351671:XDD1_RS05365
uniprot id: A0A068QSQ6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

351671:XDD1 RS03140
gene id: 351671:XDD1_RS03140
uniprot id: A0A068QP28
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

351671:XDD1 RS09250
gene id: 351671:XDD1_RS09250
uniprot id: A0A068QSU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

351671:XDD1 RS01910
gene id: 351671:XDD1_RS01910
uniprot id: A0A068QMH3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

351671:XDD1 RS00395
gene id: 351671:XDD1_RS00395
uniprot id: A0A068QMR7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

351671:XDD1 RS07995
gene id: 351671:XDD1_RS07995
uniprot id: A0A068QQW3
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

351671:XDD1 RS11225
gene id: 351671:XDD1_RS11225
uniprot id: A0A068QT13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS11260
gene id: 351671:XDD1_RS11260
uniprot id: A0A068QT26
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

351671:XDD1 RS03660
gene id: 351671:XDD1_RS03660
uniprot id: A0A068QRM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.

351671:XDD1 RS02225
gene id: 351671:XDD1_RS02225
uniprot id: A0A068QN89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

351671:XDD1 RS00510
gene id: 351671:XDD1_RS00510
uniprot id: A0A068QLZ8
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

351671:XDD1 RS16250
gene id: 351671:XDD1_RS16250
uniprot id: A0A068QZG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

351671:XDD1 RS12855
gene id: 351671:XDD1_RS12855
uniprot id: A0A068QUY8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

351671:XDD1 RS11925
gene id: 351671:XDD1_RS11925
uniprot id: A0A068QU58
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS03060
gene id: 351671:XDD1_RS03060
uniprot id: A0A068QRB1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351671:XDD1 RS00505
gene id: 351671:XDD1_RS00505
uniprot id: A0A068QPS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

351671:XDD1 RS11480
gene id: 351671:XDD1_RS11480
uniprot id: A0A068QU77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

351671:XDD1 RS07185
gene id: 351671:XDD1_RS07185
uniprot id: A0A068QQN8
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS17075
gene id: 351671:XDD1_RS17075
uniprot id: A0A068QXJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LsrG family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).

351671:XDD1 RS15580
gene id: 351671:XDD1_RS15580
uniprot id: A0A068QWM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

351671:XDD1 RS03250
gene id: 351671:XDD1_RS03250
uniprot id: A0A068QNQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

351671:XDD1 RS10340
gene id: 351671:XDD1_RS10340
uniprot id: A0A068QVP4
names: Similarity
messages: Belongs to the UDPGP type 2 family.

351671:XDD1 RS06605
gene id: 351671:XDD1_RS06605
uniprot id: A0A068QQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

351671:XDD1 RS00620
gene id: 351671:XDD1_RS00620
uniprot id: A0A068QMU5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

351671:XDD1 RS11960
gene id: 351671:XDD1_RS11960
uniprot id: A0A068QUJ7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

351671:XDD1 RS03870
gene id: 351671:XDD1_RS03870
uniprot id: A0A068QNG0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

351671:XDD1 RS00205
gene id: 351671:XDD1_RS00205
uniprot id: A0A068QPM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

351671:XDD1 RS10425
gene id: 351671:XDD1_RS10425
uniprot id: A0A068QSE9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

351671:XDD1 RS05080
gene id: 351671:XDD1_RS05080
uniprot id: A0A068QPB9
names: Similarity
messages: Belongs to the intimin/invasin family.

351671:XDD1 RS00665
gene id: 351671:XDD1_RS00665
uniprot id: A0A068QM56
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

351671:XDD1 RS10275
gene id: 351671:XDD1_RS10275
uniprot id: A0A068QSC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS10625
gene id: 351671:XDD1_RS10625
uniprot id: A0A068QSJ5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

351671:XDD1 RS16130
gene id: 351671:XDD1_RS16130
uniprot id: A0A068QWM3
names: Similarity
messages: Belongs to the pirin family.

351671:XDD1 RS05245
gene id: 351671:XDD1_RS05245
uniprot id: A0A068QP93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
messages: Monomer.

351671:XDD1 RS09570
gene id: 351671:XDD1_RS09570
uniprot id: A0A068QT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M23B family.
messages: Membrane

351671:XDD1 RS05295
gene id: 351671:XDD1_RS05295
uniprot id: A0A068QP99
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS17625
gene id: 351671:XDD1_RS17625
uniprot id: A0A068QWT5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS06050
gene id: 351671:XDD1_RS06050
uniprot id: A0A068QPL7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS15260
gene id: 351671:XDD1_RS15260
uniprot id: A0A068QW27
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS13775
gene id: 351671:XDD1_RS13775
uniprot id: A0A068QV73
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

351671:XDD1 RS06380
gene id: 351671:XDD1_RS06380
uniprot id: A0A068QQH9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

351671:XDD1 RS17500
gene id: 351671:XDD1_RS17500
uniprot id: A0A068QXR6
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01040
gene id: 351671:XDD1_RS01040
uniprot id: A0A068QM55
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS03845
gene id: 351671:XDD1_RS03845
uniprot id: A0A068QNF6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

351671:XDD1 RS11130
gene id: 351671:XDD1_RS11130
uniprot id: A0A068QSZ1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

351671:XDD1 RS04320
gene id: 351671:XDD1_RS04320
uniprot id: A0A068QPB3
names: Function
messages: Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.

351671:XDD1 RS01675
gene id: 351671:XDD1_RS01675
uniprot id: A0A068QMI3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

351671:XDD1 RS10295
gene id: 351671:XDD1_RS10295
uniprot id: A0A068QTE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS14790
gene id: 351671:XDD1_RS14790
uniprot id: A0A068QV60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
messages: Cytoplasm

351671:XDD1 RS02130
gene id: 351671:XDD1_RS02130
uniprot id: A0A068QQP0
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS04130
gene id: 351671:XDD1_RS04130
uniprot id: A0A068QRW6
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS08065
gene id: 351671:XDD1_RS08065
uniprot id: A0A068QQX5
names: Similarity
messages: Belongs to the peptidase S41A family.

351671:XDD1 RS02995
gene id: 351671:XDD1_RS02995
uniprot id: A0A068QN26
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

351671:XDD1 RS07695
gene id: 351671:XDD1_RS07695
uniprot id: A0A068QRG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS13755
gene id: 351671:XDD1_RS13755
uniprot id: A0A068QV68
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

351671:XDD1 RS16885
gene id: 351671:XDD1_RS16885
uniprot id: A0A068QZT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

351671:XDD1 RS02095
gene id: 351671:XDD1_RS02095
uniprot id: A0A068QMK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

351671:XDD1 RS16535
gene id: 351671:XDD1_RS16535
uniprot id: A0A068QWA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

351671:XDD1 RS03580
gene id: 351671:XDD1_RS03580
uniprot id: A0A068QNC0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

351671:XDD1 RS16875
gene id: 351671:XDD1_RS16875
uniprot id: A0A068QWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

351671:XDD1 RS11310
gene id: 351671:XDD1_RS11310
uniprot id: A0A068QW99
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtC forms a heteromultimer with MdtB.

351671:XDD1 RS03100
gene id: 351671:XDD1_RS03100
uniprot id: A0A068QN99
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

351671:XDD1 RS03350
gene id: 351671:XDD1_RS03350
uniprot id: A0A068QRG8
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

351671:XDD1 RS12760
gene id: 351671:XDD1_RS12760
uniprot id: A0A068QTV7
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS02445
gene id: 351671:XDD1_RS02445
uniprot id: A0A068QNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

351671:XDD1 RS15445
gene id: 351671:XDD1_RS15445
uniprot id: A0A068QVP2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS08310
gene id: 351671:XDD1_RS08310
uniprot id: A0A068QS74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

351671:XDD1 RS07920
gene id: 351671:XDD1_RS07920
uniprot id: A0A068QRY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-lipid IV(A) to form a Kdo(2)-(acyl)-lipid IV(A).
messages: Cell inner membrane

351671:XDD1 RS00480
gene id: 351671:XDD1_RS00480
uniprot id: A0A068QM35
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01985
gene id: 351671:XDD1_RS01985
uniprot id: A0A068QNG5
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

351671:XDD1 RS02125
gene id: 351671:XDD1_RS02125
uniprot id: A0A068QN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS00385
gene id: 351671:XDD1_RS00385
uniprot id: A0A068QMF4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351671:XDD1 RS04585
gene id: 351671:XDD1_RS04585
uniprot id: A0A068QS91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

351671:XDD1 RS12550
gene id: 351671:XDD1_RS12550
uniprot id: A0A068QX34
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

351671:XDD1 RS00445
gene id: 351671:XDD1_RS00445
uniprot id: A0A068QMS3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

351671:XDD1 RS12520
gene id: 351671:XDD1_RS12520
uniprot id: A0A068QUE4
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS00610
gene id: 351671:XDD1_RS00610
uniprot id: A0A068QMI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

351671:XDD1 RS00400
gene id: 351671:XDD1_RS00400
uniprot id: A0A068QLZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS11910
gene id: 351671:XDD1_RS11910
uniprot id: A0A068QUI9
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01500
gene id: 351671:XDD1_RS01500
uniprot id: A0A068QN87
names: Similarity
messages: Belongs to the DprA/Smf family.

351671:XDD1 RS10725
gene id: 351671:XDD1_RS10725
uniprot id: A0A068QTA1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

351671:XDD1 RS17880
gene id: 351671:XDD1_RS17880
uniprot id: A0A068R0C9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS14490
gene id: 351671:XDD1_RS14490
uniprot id: A0A068QV10
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

351671:XDD1 RS14600
gene id: 351671:XDD1_RS14600
uniprot id: A0A068QV61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

351671:XDD1 RS16245
gene id: 351671:XDD1_RS16245
uniprot id: A0A068QWQ0
names: Similarity
messages: Belongs to the peptidase S1C family.

351671:XDD1 RS15545
gene id: 351671:XDD1_RS15545
uniprot id: A0A068QVL7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05910
gene id: 351671:XDD1_RS05910
uniprot id: A0A068QPP7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

351671:XDD1 RS13230
gene id: 351671:XDD1_RS13230
uniprot id: A0A068QU57
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

351671:XDD1 RS00735
gene id: 351671:XDD1_RS00735
uniprot id: A0A068QM21
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

351671:XDD1 RS16430
gene id: 351671:XDD1_RS16430
uniprot id: A0A068QW92
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

351671:XDD1 RS03930
gene id: 351671:XDD1_RS03930
uniprot id: A0A068QRS6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

351671:XDD1 RS01070
gene id: 351671:XDD1_RS01070
uniprot id: A0A068QMN3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

351671:XDD1 RS01355
gene id: 351671:XDD1_RS01355
uniprot id: A0A068QM98
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

351671:XDD1 RS05925
gene id: 351671:XDD1_RS05925
uniprot id: A0A068QQP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

351671:XDD1 RS15605
gene id: 351671:XDD1_RS15605
uniprot id: A0A068QWM7
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

351671:XDD1 RS08820
gene id: 351671:XDD1_RS08820
uniprot id: A0A068QRD2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

351671:XDD1 RS08095
gene id: 351671:XDD1_RS08095
uniprot id: A0A068QS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS02185
gene id: 351671:XDD1_RS02185
uniprot id: A0A068QN78
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

351671:XDD1 RS16105
gene id: 351671:XDD1_RS16105
uniprot id: A0A068QWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS14730
gene id: 351671:XDD1_RS14730
uniprot id: A0A068QYI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

351671:XDD1 RS15365
gene id: 351671:XDD1_RS15365
uniprot id: A0A068QVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I38 family.
messages: Periplasm

351671:XDD1 RS04045
gene id: 351671:XDD1_RS04045
uniprot id: A0A068QRU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane
messages: The cytochrome bo(3) ubiquinol oxidase complex is a heterooctamer of two A chains, two B chains, two C chains and two D chains.

351671:XDD1 RS16890
gene id: 351671:XDD1_RS16890
uniprot id: A0A068QXG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

351671:XDD1 RS02555
gene id: 351671:XDD1_RS02555
uniprot id: A0A068QNV2
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351671:XDD1 RS15635
gene id: 351671:XDD1_RS15635
uniprot id: A0A068QVT3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

351671:XDD1 RS07425
gene id: 351671:XDD1_RS07425
uniprot id: A0A068QU00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

351671:XDD1 RS15435
gene id: 351671:XDD1_RS15435
uniprot id: A0A068QWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS12050
gene id: 351671:XDD1_RS12050
uniprot id: A0A068QWU8
names: Similarity
messages: Belongs to the ParB family.

351671:XDD1 RS05405
gene id: 351671:XDD1_RS05405
uniprot id: A0A068QQ06
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

351671:XDD1 RS15280
gene id: 351671:XDD1_RS15280
uniprot id: A0A068QVJ7
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

351671:XDD1 RS02020
gene id: 351671:XDD1_RS02020
uniprot id: A0A068QMN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

351671:XDD1 RS11845
gene id: 351671:XDD1_RS11845
uniprot id: A0A068QTE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS11405
gene id: 351671:XDD1_RS11405
uniprot id: A0A068QWC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs.
messages: Cytoplasm
messages: Interacts with TusE.

351671:XDD1 RS13055
gene id: 351671:XDD1_RS13055
uniprot id: A0A068QV31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
messages: Cytoplasm
messages: Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).

351671:XDD1 RS03365
gene id: 351671:XDD1_RS03365
uniprot id: A0A068QND7
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

351671:XDD1 RS05645
gene id: 351671:XDD1_RS05645
uniprot id: A0A068QQJ2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS08915
gene id: 351671:XDD1_RS08915
uniprot id: A0A068QRL0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS00820
gene id: 351671:XDD1_RS00820
uniprot id: A0A068QPX8
names: Similarity
messages: Belongs to the polysaccharide synthase family.

351671:XDD1 RS13330
gene id: 351671:XDD1_RS13330
uniprot id: A0A068QU85
names: Similarity
messages: Belongs to the citrate synthase family.

351671:XDD1 RS12835
gene id: 351671:XDD1_RS12835
uniprot id: A0A068QTX2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

351671:XDD1 RS07415
gene id: 351671:XDD1_RS07415
uniprot id: A0A068QQS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

351671:XDD1 RS06250
gene id: 351671:XDD1_RS06250
uniprot id: A0A068QQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

351671:XDD1 RS02265
gene id: 351671:XDD1_RS02265
uniprot id: A0A068QQS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

351671:XDD1 RS03255
gene id: 351671:XDD1_RS03255
uniprot id: A0A068QP45
names: Similarity
messages: Belongs to the UPF0145 family.

351671:XDD1 RS01975
gene id: 351671:XDD1_RS01975
uniprot id: A0A068QN29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

351671:XDD1 RS00435
gene id: 351671:XDD1_RS00435
uniprot id: A0A068QMF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IgaA family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS15210
gene id: 351671:XDD1_RS15210
uniprot id: A0A068QW16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

351671:XDD1 RS12100
gene id: 351671:XDD1_RS12100
uniprot id: A0A068QWV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).

351671:XDD1 RS11485
gene id: 351671:XDD1_RS11485
uniprot id: A0A068QT65
names: Function
names: Similarity
messages: Belongs to the thiamine kinase family.
messages: Catalyzes the phosphorylation of thiamine to thiamine phosphate.

351671:XDD1 RS14630
gene id: 351671:XDD1_RS14630
uniprot id: A0A068QYH0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS17185
gene id: 351671:XDD1_RS17185
uniprot id: A0A068QWQ3
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS08685
gene id: 351671:XDD1_RS08685
uniprot id: A0A068QUN7
names: Similarity
messages: Belongs to the PspA/IM30 family.

351671:XDD1 RS00245
gene id: 351671:XDD1_RS00245
uniprot id: A0A068QME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

351671:XDD1 RS11540
gene id: 351671:XDD1_RS11540
uniprot id: A0A068QT98
names: Similarity
messages: Belongs to the fabD family.

351671:XDD1 RS06275
gene id: 351671:XDD1_RS06275
uniprot id: A0A068QQF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

351671:XDD1 RS07900
gene id: 351671:XDD1_RS07900
uniprot id: A0A068QU86
names: Similarity
messages: Belongs to the PhzF family.

351671:XDD1 RS14615
gene id: 351671:XDD1_RS14615
uniprot id: A0A068QV34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

351671:XDD1 RS02375
gene id: 351671:XDD1_RS02375
uniprot id: A0A068QNB8
names: Similarity
messages: Belongs to the RutC family.

351671:XDD1 RS04315
gene id: 351671:XDD1_RS04315
uniprot id: A0A068QNU2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS11400
gene id: 351671:XDD1_RS11400
uniprot id: A0A068QTR6
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

351671:XDD1 RS03995
gene id: 351671:XDD1_RS03995
uniprot id: A0A068QRU0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

351671:XDD1 RS11590
gene id: 351671:XDD1_RS11590
uniprot id: A0A068QTA9
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

351671:XDD1 RS02070
gene id: 351671:XDD1_RS02070
uniprot id: A0A068QNI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

351671:XDD1 RS10465
gene id: 351671:XDD1_RS10465
uniprot id: A0A068QSJ1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12105
gene id: 351671:XDD1_RS12105
uniprot id: A0A068QUL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadJ) and two beta chains (FadI).
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

351671:XDD1 RS10910
gene id: 351671:XDD1_RS10910
uniprot id: A0A068QW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

351671:XDD1 RS16920
gene id: 351671:XDD1_RS16920
uniprot id: A0A068QWF7
names: Similarity
messages: Belongs to the SlyX family.

351671:XDD1 RS02035
gene id: 351671:XDD1_RS02035
uniprot id: A0A068QMN9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

351671:XDD1 RS05395
gene id: 351671:XDD1_RS05395
uniprot id: A0A068QPB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS03520
gene id: 351671:XDD1_RS03520
uniprot id: A0A068QRJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

351671:XDD1 RS07930
gene id: 351671:XDD1_RS07930
uniprot id: A0A068QR09
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS04260
gene id: 351671:XDD1_RS04260
uniprot id: A0A068QNP7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

351671:XDD1 RS00965
gene id: 351671:XDD1_RS00965
uniprot id: A0A068QMZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

351671:XDD1 RS16925
gene id: 351671:XDD1_RS16925
uniprot id: A0A068QWL1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351671:XDD1 RS14140
gene id: 351671:XDD1_RS14140
uniprot id: A0A068QVX0
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05640
gene id: 351671:XDD1_RS05640
uniprot id: A0A068QQ41
names: Similarity
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

351671:XDD1 RS02365
gene id: 351671:XDD1_RS02365
uniprot id: A0A068QNQ3
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

351671:XDD1 RS14465
gene id: 351671:XDD1_RS14465
uniprot id: A0A068QV05
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351671:XDD1 RS16675
gene id: 351671:XDD1_RS16675
uniprot id: A0A068QWH6
names: Similarity
messages: Belongs to the GARS family.

351671:XDD1 RS17785
gene id: 351671:XDD1_RS17785
uniprot id: A0A068QXY4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

351671:XDD1 RS08585
gene id: 351671:XDD1_RS08585
uniprot id: A0A068QUL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS10320
gene id: 351671:XDD1_RS10320
uniprot id: A0A068QTF4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

351671:XDD1 RS01825
gene id: 351671:XDD1_RS01825
uniprot id: A0A068QMK7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

351671:XDD1 RS01000
gene id: 351671:XDD1_RS01000
uniprot id: A0A068QM94
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351671:XDD1 RS16470
gene id: 351671:XDD1_RS16470
uniprot id: A0A068QXA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

351671:XDD1 RS03030
gene id: 351671:XDD1_RS03030
uniprot id: A0A068QNN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS16915
gene id: 351671:XDD1_RS16915
uniprot id: A0A068QXH2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351671:XDD1 RS05445
gene id: 351671:XDD1_RS05445
uniprot id: A0A068QPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

351671:XDD1 RS10385
gene id: 351671:XDD1_RS10385
uniprot id: A0A068QT18
names: Similarity
messages: Belongs to the peptidase S49 family.

351671:XDD1 RS02955
gene id: 351671:XDD1_RS02955
uniprot id: A0A068QR94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

351671:XDD1 RS16565
gene id: 351671:XDD1_RS16565
uniprot id: A0A068QWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

351671:XDD1 RS14520
gene id: 351671:XDD1_RS14520
uniprot id: A0A068QVP3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

351671:XDD1 RS13645
gene id: 351671:XDD1_RS13645
uniprot id: A0A068QXS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS09745
gene id: 351671:XDD1_RS09745
uniprot id: A0A068QVD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

351671:XDD1 RS07180
gene id: 351671:XDD1_RS07180
uniprot id: A0A068QQH1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06550
gene id: 351671:XDD1_RS06550
uniprot id: A0A068QPY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS10830
gene id: 351671:XDD1_RS10830
uniprot id: A0A068QTR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

351671:XDD1 RS11330
gene id: 351671:XDD1_RS11330
uniprot id: A0A068QTQ0
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

351671:XDD1 RS07320
gene id: 351671:XDD1_RS07320
uniprot id: A0A068QQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

351671:XDD1 RS03925
gene id: 351671:XDD1_RS03925
uniprot id: A0A068QP23
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

351671:XDD1 RS12215
gene id: 351671:XDD1_RS12215
uniprot id: A0A068QWX7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS09605
gene id: 351671:XDD1_RS09605
uniprot id: A0A068QSN5
names: Similarity
messages: Belongs to the RutC family.

351671:XDD1 RS00785
gene id: 351671:XDD1_RS00785
uniprot id: A0A068QM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

351671:XDD1 RS04310
gene id: 351671:XDD1_RS04310
uniprot id: A0A068QNQ5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS10090
gene id: 351671:XDD1_RS10090
uniprot id: A0A068QTB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

351671:XDD1 RS09555
gene id: 351671:XDD1_RS09555
uniprot id: A0A068QS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS07165
gene id: 351671:XDD1_RS07165
uniprot id: A0A068QR65
names: Similarity
messages: Belongs to the ClpA/ClpB family.

351671:XDD1 RS08540
gene id: 351671:XDD1_RS08540
uniprot id: A0A068QR66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YkuD family.
messages: Periplasm

351671:XDD1 RS13760
gene id: 351671:XDD1_RS13760
uniprot id: A0A068QXU4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

351671:XDD1 RS11515
gene id: 351671:XDD1_RS11515
uniprot id: A0A068QT92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

351671:XDD1 RS04000
gene id: 351671:XDD1_RS04000
uniprot id: A0A068QPJ1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

351671:XDD1 RS14590
gene id: 351671:XDD1_RS14590
uniprot id: A0A068QW41
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

351671:XDD1 RS11720
gene id: 351671:XDD1_RS11720
uniprot id: A0A068QTD2
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: To H.influenzae HI_0842.

351671:XDD1 RS04035
gene id: 351671:XDD1_RS04035
uniprot id: A0A068QNP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

351671:XDD1 RS03405
gene id: 351671:XDD1_RS03405
uniprot id: A0A068QP73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

351671:XDD1 RS10900
gene id: 351671:XDD1_RS10900
uniprot id: A0A068QSU5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

351671:XDD1 RS04430
gene id: 351671:XDD1_RS04430
uniprot id: A0A068QPD8
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

351671:XDD1 RS13720
gene id: 351671:XDD1_RS13720
uniprot id: A0A068QVJ5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01880
gene id: 351671:XDD1_RS01880
uniprot id: A0A068QNE8
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

351671:XDD1 RS03300
gene id: 351671:XDD1_RS03300
uniprot id: A0A068QNR9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS14925
gene id: 351671:XDD1_RS14925
uniprot id: A0A068QV82
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS01970
gene id: 351671:XDD1_RS01970
uniprot id: A0A068QMM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS08600
gene id: 351671:XDD1_RS08600
uniprot id: A0A068QRE5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.
messages: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.

351671:XDD1 RS03820
gene id: 351671:XDD1_RS03820
uniprot id: A0A068QNF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

351671:XDD1 RS10510
gene id: 351671:XDD1_RS10510
uniprot id: A0A068QSK3
names: Similarity
messages: Belongs to the group II decarboxylase family.

351671:XDD1 RS00260
gene id: 351671:XDD1_RS00260
uniprot id: A0A068QLY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

351671:XDD1 RS13070
gene id: 351671:XDD1_RS13070
uniprot id: A0A068QUQ3
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

351671:XDD1 RS12125
gene id: 351671:XDD1_RS12125
uniprot id: A0A068QWV9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

351671:XDD1 RS14125
gene id: 351671:XDD1_RS14125
uniprot id: A0A068QUY5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

351671:XDD1 RS17570
gene id: 351671:XDD1_RS17570
uniprot id: A0A068R063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

351671:XDD1 RS18120
gene id: 351671:XDD1_RS18120
uniprot id: A0A068QXA8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

351671:XDD1 RS02830
gene id: 351671:XDD1_RS02830
uniprot id: A0A068QR70
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

351671:XDD1 RS15475
gene id: 351671:XDD1_RS15475
uniprot id: A0A068QYY2
names: Similarity
messages: Belongs to the SufE family.

351671:XDD1 RS08275
gene id: 351671:XDD1_RS08275
uniprot id: A0A068QRR5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

351671:XDD1 RS18770
gene id: 351671:XDD1_RS18770
uniprot id: A0A068QPT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export.
messages: Belongs to the AcrZ family.
messages: Cell membrane
messages: Part of the AcrA-AcrB-AcrZ-TolC efflux pump, interacts directly with AcrB.

351671:XDD1 RS15695
gene id: 351671:XDD1_RS15695
uniprot id: A0A068QWP9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

351671:XDD1 RS09600
gene id: 351671:XDD1_RS09600
uniprot id: A0A068QS40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS10550
gene id: 351671:XDD1_RS10550
uniprot id: A0A068QSI1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS07985
gene id: 351671:XDD1_RS07985
uniprot id: A0A068QUA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

351671:XDD1 RS13665
gene id: 351671:XDD1_RS13665
uniprot id: A0A068QV48
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

351671:XDD1 RS04150
gene id: 351671:XDD1_RS04150
uniprot id: A0A068QP70
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

351671:XDD1 RS05685
gene id: 351671:XDD1_RS05685
uniprot id: A0A068QQ48
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

351671:XDD1 RS11780
gene id: 351671:XDD1_RS11780
uniprot id: A0A068QWR1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

351671:XDD1 RS06210
gene id: 351671:XDD1_RS06210
uniprot id: A0A068QPW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

351671:XDD1 RS15640
gene id: 351671:XDD1_RS15640
uniprot id: A0A068QWA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

351671:XDD1 RS09565
gene id: 351671:XDD1_RS09565
uniprot id: A0A068QVB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Periplasm

351671:XDD1 RS16685
gene id: 351671:XDD1_RS16685
uniprot id: A0A068QZQ6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

351671:XDD1 RS01250
gene id: 351671:XDD1_RS01250
uniprot id: A0A068QQ57
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

351671:XDD1 RS07235
gene id: 351671:XDD1_RS07235
uniprot id: A0A068QTX3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS10590
gene id: 351671:XDD1_RS10590
uniprot id: A0A068QVU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

351671:XDD1 RS00305
gene id: 351671:XDD1_RS00305
uniprot id: A0A068QMQ7
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

351671:XDD1 RS16730
gene id: 351671:XDD1_RS16730
uniprot id: A0A068QX20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

351671:XDD1 RS05840
gene id: 351671:XDD1_RS05840
uniprot id: A0A068QPN3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

351671:XDD1 RS10775
gene id: 351671:XDD1_RS10775
uniprot id: A0A068QTB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

351671:XDD1 RS02285
gene id: 351671:XDD1_RS02285
uniprot id: A0A068QN98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

351671:XDD1 RS17715
gene id: 351671:XDD1_RS17715
uniprot id: A0A068R099
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

351671:XDD1 RS18125
gene id: 351671:XDD1_RS18125
uniprot id: A0A068QXS9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

351671:XDD1 RS11300
gene id: 351671:XDD1_RS11300
uniprot id: A0A068QT40
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC.

351671:XDD1 RS13920
gene id: 351671:XDD1_RS13920
uniprot id: A0A068QVQ3
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

351671:XDD1 RS02190
gene id: 351671:XDD1_RS02190
uniprot id: A0A068QQR0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

351671:XDD1 RS08090
gene id: 351671:XDD1_RS08090
uniprot id: A0A068QUC4
names: Similarity
messages: Belongs to the fructosamine kinase family.

351671:XDD1 RS11635
gene id: 351671:XDD1_RS11635
uniprot id: A0A068QTE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

351671:XDD1 RS14585
gene id: 351671:XDD1_RS14585
uniprot id: A0A068QYG1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.

351671:XDD1 RS13305
gene id: 351671:XDD1_RS13305
uniprot id: A0A068QV88
names: Function
names: Similarity
messages: Belongs to the chloramphenicol acetyltransferase family.
messages: This enzyme is an effector of chloramphenicol resistance in bacteria.

351671:XDD1 RS16710
gene id: 351671:XDD1_RS16710
uniprot id: A0A068QZQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

351671:XDD1 RS01320
gene id: 351671:XDD1_RS01320
uniprot id: A0A068QWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

351671:XDD1 RS01390
gene id: 351671:XDD1_RS01390
uniprot id: A0A068QMT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

351671:XDD1 RS10135
gene id: 351671:XDD1_RS10135
uniprot id: A0A068QVK4
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

351671:XDD1 RS11145
gene id: 351671:XDD1_RS11145
uniprot id: A0A068QTY5
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS17535
gene id: 351671:XDD1_RS17535
uniprot id: A0A068QXS3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351671:XDD1 RS07115
gene id: 351671:XDD1_RS07115
uniprot id: A0A068QQM6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

351671:XDD1 RS10555
gene id: 351671:XDD1_RS10555
uniprot id: A0A068QSL3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS04235
gene id: 351671:XDD1_RS04235
uniprot id: A0A068QNP3
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the phosphorylation of guanosine and inosine to GMP and IMP, respectively.

351671:XDD1 RS04205
gene id: 351671:XDD1_RS04205
uniprot id: A0A068QNS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

351671:XDD1 RS04350
gene id: 351671:XDD1_RS04350
uniprot id: A0A068QS26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

351671:XDD1 RS09060
gene id: 351671:XDD1_RS09060
uniprot id: A0A068QS92
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS17375
gene id: 351671:XDD1_RS17375
uniprot id: A0A068QXP3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

351671:XDD1 RS00995
gene id: 351671:XDD1_RS00995
uniprot id: A0A068QM49
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

351671:XDD1 RS03370
gene id: 351671:XDD1_RS03370
uniprot id: A0A068QNS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

351671:XDD1 RS15270
gene id: 351671:XDD1_RS15270
uniprot id: A0A068QWF5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

351671:XDD1 RS19045
gene id: 351671:XDD1_RS19045
uniprot id: A0A068QXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

351671:XDD1 RS03620
gene id: 351671:XDD1_RS03620
uniprot id: A0A068QPB5
names: Similarity
messages: Belongs to the threonine synthase family.

351671:XDD1 RS06045
gene id: 351671:XDD1_RS06045
uniprot id: A0A068QQR9
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

351671:XDD1 RS17000
gene id: 351671:XDD1_RS17000
uniprot id: A0A068QWM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

351671:XDD1 RS16300
gene id: 351671:XDD1_RS16300
uniprot id: A0A068QZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

351671:XDD1 RS03685
gene id: 351671:XDD1_RS03685
uniprot id: A0A068QRM8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

351671:XDD1 RS11125
gene id: 351671:XDD1_RS11125
uniprot id: A0A068QSX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

351671:XDD1 RS04090
gene id: 351671:XDD1_RS04090
uniprot id: A0A068QPK8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

351671:XDD1 RS03630
gene id: 351671:XDD1_RS03630
uniprot id: A0A068QNH6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

351671:XDD1 RS12965
gene id: 351671:XDD1_RS12965
uniprot id: A0A068QU20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

351671:XDD1 RS03795
gene id: 351671:XDD1_RS03795
uniprot id: A0A068QNF0
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

351671:XDD1 RS06040
gene id: 351671:XDD1_RS06040
uniprot id: A0A068QT23
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

351671:XDD1 RS15615
gene id: 351671:XDD1_RS15615
uniprot id: A0A068QVS7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

351671:XDD1 RS18310
gene id: 351671:XDD1_RS18310
uniprot id: A0A068QXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS12260
gene id: 351671:XDD1_RS12260
uniprot id: A0A068QUA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedD family.
messages: Cell inner membrane
messages: Non-essential cell division protein that could be required for efficient cell constriction.
messages: The SPOR domain binds septal peptidoglycans and is required to target DedD to the septal ring.

351671:XDD1 RS15275
gene id: 351671:XDD1_RS15275
uniprot id: A0A068QVE9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

351671:XDD1 RS07865
gene id: 351671:XDD1_RS07865
uniprot id: A0A068QR00
names: Similarity
messages: Belongs to the YbiA family.

351671:XDD1 RS17590
gene id: 351671:XDD1_RS17590
uniprot id: A0A068R068
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

351671:XDD1 RS01360
gene id: 351671:XDD1_RS01360
uniprot id: A0A068QMD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

351671:XDD1 RS10155
gene id: 351671:XDD1_RS10155
uniprot id: A0A068QSX8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS13045
gene id: 351671:XDD1_RS13045
uniprot id: A0A068QUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

351671:XDD1 RS00470
gene id: 351671:XDD1_RS00470
uniprot id: A0A068QMS6
names: Function
names: Similarity
messages: Belongs to the LuxC family.
messages: LuxC is the fatty acid reductase enzyme responsible for synthesis of the aldehyde substrate for the luminescent reaction catalyzed by luciferase.

351671:XDD1 RS10235
gene id: 351671:XDD1_RS10235
uniprot id: A0A068QSE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

351671:XDD1 RS17495
gene id: 351671:XDD1_RS17495
uniprot id: A0A068R045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 5 family.
messages: Periplasm

351671:XDD1 RS16700
gene id: 351671:XDD1_RS16700
uniprot id: A0A068QWI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS15710
gene id: 351671:XDD1_RS15710
uniprot id: A0A068QWC4
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

351671:XDD1 RS16795
gene id: 351671:XDD1_RS16795
uniprot id: A0A068QWJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS07240
gene id: 351671:XDD1_RS07240
uniprot id: A0A068QRN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

351671:XDD1 RS05440
gene id: 351671:XDD1_RS05440
uniprot id: A0A068QPC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

351671:XDD1 RS12820
gene id: 351671:XDD1_RS12820
uniprot id: A0A068QUK7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

351671:XDD1 RS01755
gene id: 351671:XDD1_RS01755
uniprot id: A0A068QNC5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

351671:XDD1 RS15505
gene id: 351671:XDD1_RS15505
uniprot id: A0A068QW77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: Homohexamer.

351671:XDD1 RS03670
gene id: 351671:XDD1_RS03670
uniprot id: A0A068QND4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

351671:XDD1 RS09110
gene id: 351671:XDD1_RS09110
uniprot id: A0A068QUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351671:XDD1 RS14400
gene id: 351671:XDD1_RS14400
uniprot id: A0A068QVM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

351671:XDD1 RS11220
gene id: 351671:XDD1_RS11220
uniprot id: A0A068QTZ9
names: Similarity
messages: Belongs to the GppA/Ppx family.

351671:XDD1 RS14115
gene id: 351671:XDD1_RS14115
uniprot id: A0A068QVW9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS07175
gene id: 351671:XDD1_RS07175
uniprot id: A0A068QRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

351671:XDD1 RS06710
gene id: 351671:XDD1_RS06710
uniprot id: A0A068QQ24
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS16555
gene id: 351671:XDD1_RS16555
uniprot id: A0A068QXB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

351671:XDD1 RS12515
gene id: 351671:XDD1_RS12515
uniprot id: A0A068QTT5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

351671:XDD1 RS17530
gene id: 351671:XDD1_RS17530
uniprot id: A0A068R056
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351671:XDD1 RS06085
gene id: 351671:XDD1_RS06085
uniprot id: A0A068QQC5
names: Similarity
messages: Belongs to the CcdB toxin family.

351671:XDD1 RS06585
gene id: 351671:XDD1_RS06585
uniprot id: A0A068QQN5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

351671:XDD1 RS10720
gene id: 351671:XDD1_RS10720
uniprot id: A0A068QSQ4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

351671:XDD1 RS13015
gene id: 351671:XDD1_RS13015
uniprot id: A0A068QU33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS17775
gene id: 351671:XDD1_RS17775
uniprot id: A0A068QXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS11195
gene id: 351671:XDD1_RS11195
uniprot id: A0A068QTZ5
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

351671:XDD1 RS07980
gene id: 351671:XDD1_RS07980
uniprot id: A0A068QRK6
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS16870
gene id: 351671:XDD1_RS16870
uniprot id: A0A068QWF0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS01585
gene id: 351671:XDD1_RS01585
uniprot id: A0A068QMV7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS11530
gene id: 351671:XDD1_RS11530
uniprot id: A0A068QU92
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

351671:XDD1 RS05505
gene id: 351671:XDD1_RS05505
uniprot id: A0A068QST3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

351671:XDD1 RS16695
gene id: 351671:XDD1_RS16695
uniprot id: A0A068QWC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

351671:XDD1 RS05500
gene id: 351671:XDD1_RS05500
uniprot id: A0A068QQ22
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06235
gene id: 351671:XDD1_RS06235
uniprot id: A0A068QT61
names: Similarity
messages: Belongs to the citrate synthase family.

351671:XDD1 RS09615
gene id: 351671:XDD1_RS09615
uniprot id: A0A068QT44
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

351671:XDD1 RS06255
gene id: 351671:XDD1_RS06255
uniprot id: A0A068QT67
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

351671:XDD1 RS10200
gene id: 351671:XDD1_RS10200
uniprot id: A0A068QTD1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

351671:XDD1 RS08215
gene id: 351671:XDD1_RS08215
uniprot id: A0A068QS53
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
messages: Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.

351671:XDD1 RS10225
gene id: 351671:XDD1_RS10225
uniprot id: A0A068QTD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS04565
gene id: 351671:XDD1_RS04565
uniprot id: A0A068QPY5
names: Function
names: Subunit
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.
messages: The DNA polymerase holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential subassemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core (subunits alpha,epsilon and theta) contains the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. This complex contains delta, delta', psi and chi, and copies of either or both of two different DnaX proteins, gamma and tau.

351671:XDD1 RS14840
gene id: 351671:XDD1_RS14840
uniprot id: A0A068QVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

351671:XDD1 RS03880
gene id: 351671:XDD1_RS03880
uniprot id: A0A068QRR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

351671:XDD1 RS13090
gene id: 351671:XDD1_RS13090
uniprot id: A0A068QU51
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

351671:XDD1 RS05915
gene id: 351671:XDD1_RS05915
uniprot id: A0A068QQ96
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

351671:XDD1 RS13780
gene id: 351671:XDD1_RS13780
uniprot id: A0A068QXV0
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

351671:XDD1 RS07720
gene id: 351671:XDD1_RS07720
uniprot id: A0A068QRG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

351671:XDD1 RS15250
gene id: 351671:XDD1_RS15250
uniprot id: A0A068QVE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Homodimer.

351671:XDD1 RS02945
gene id: 351671:XDD1_RS02945
uniprot id: A0A068QP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS04055
gene id: 351671:XDD1_RS04055
uniprot id: A0A068QNK0
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

351671:XDD1 RS13000
gene id: 351671:XDD1_RS13000
uniprot id: A0A068QXC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

351671:XDD1 RS00605
gene id: 351671:XDD1_RS00605
uniprot id: A0A068QM07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

351671:XDD1 RS12400
gene id: 351671:XDD1_RS12400
uniprot id: A0A068QX12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

351671:XDD1 RS12350
gene id: 351671:XDD1_RS12350
uniprot id: A0A068QUC2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS15235
gene id: 351671:XDD1_RS15235
uniprot id: A0A068QW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

351671:XDD1 RS15775
gene id: 351671:XDD1_RS15775
uniprot id: A0A068QWR9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

351671:XDD1 RS16050
gene id: 351671:XDD1_RS16050
uniprot id: A0A068QVX9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

351671:XDD1 RS08200
gene id: 351671:XDD1_RS08200
uniprot id: A0A068QR61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
messages: Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homodimer.

351671:XDD1 RS11565
gene id: 351671:XDD1_RS11565
uniprot id: A0A068QTA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

351671:XDD1 RS08165
gene id: 351671:XDD1_RS08165
uniprot id: A0A068QS41
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS03500
gene id: 351671:XDD1_RS03500
uniprot id: A0A068QP90
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

351671:XDD1 RS18145
gene id: 351671:XDD1_RS18145
uniprot id: A0A068QXB5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

351671:XDD1 RS12890
gene id: 351671:XDD1_RS12890
uniprot id: A0A068QU06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity. Interacts with IscU.

351671:XDD1 RS15745
gene id: 351671:XDD1_RS15745
uniprot id: A0A068QWR2
names: Function
names: Miscellaneous
names: Similarity
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.

351671:XDD1 RS11675
gene id: 351671:XDD1_RS11675
uniprot id: A0A068QTC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxT phosphotransferase family.
messages: Cell inner membrane
messages: Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1-diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P).

351671:XDD1 RS08115
gene id: 351671:XDD1_RS08115
uniprot id: A0A068QUC7
names: Similarity
messages: Belongs to the transglycosylase Slt family.

351671:XDD1 RS08045
gene id: 351671:XDD1_RS08045
uniprot id: A0A068QR27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Membrane

351671:XDD1 RS10855
gene id: 351671:XDD1_RS10855
uniprot id: A0A068QST4
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS10140
gene id: 351671:XDD1_RS10140
uniprot id: A0A068QTB8
names: Similarity
messages: Belongs to the SUI1 family.

351671:XDD1 RS18580
gene id: 351671:XDD1_RS18580
uniprot id: A0A068QQM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

351671:XDD1 RS08205
gene id: 351671:XDD1_RS08205
uniprot id: A0A068QRQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell membrane

351671:XDD1 RS11555
gene id: 351671:XDD1_RS11555
uniprot id: A0A068QU98
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

351671:XDD1 RS14595
gene id: 351671:XDD1_RS14595
uniprot id: A0A068QV30
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

351671:XDD1 RS16180
gene id: 351671:XDD1_RS16180
uniprot id: A0A068QX18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

351671:XDD1 RS12280
gene id: 351671:XDD1_RS12280
uniprot id: A0A068QTQ1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

351671:XDD1 RS07310
gene id: 351671:XDD1_RS07310
uniprot id: A0A068QRQ2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS17295
gene id: 351671:XDD1_RS17295
uniprot id: A0A068QXM7
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS06305
gene id: 351671:XDD1_RS06305
uniprot id: A0A068QQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

351671:XDD1 RS04550
gene id: 351671:XDD1_RS04550
uniprot id: A0A068QNZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

351671:XDD1 RS07370
gene id: 351671:XDD1_RS07370
uniprot id: A0A068QRA3
names: Similarity
messages: Belongs to the peptidase M1 family.

351671:XDD1 RS15035
gene id: 351671:XDD1_RS15035
uniprot id: A0A068QVA6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

351671:XDD1 RS02460
gene id: 351671:XDD1_RS02460
uniprot id: A0A068QNF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS09130
gene id: 351671:XDD1_RS09130
uniprot id: A0A068QSB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

351671:XDD1 RS12160
gene id: 351671:XDD1_RS12160
uniprot id: A0A068QTN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS00230
gene id: 351671:XDD1_RS00230
uniprot id: A0A068QMP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

351671:XDD1 RS13080
gene id: 351671:XDD1_RS13080
uniprot id: A0A068QV36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

351671:XDD1 RS13905
gene id: 351671:XDD1_RS13905
uniprot id: A0A068QUQ6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
messages: Repressed under conditions of excess protein secretion capacity and derepressed when protein secretion becomes limiting. This is regulated by SecM.

351671:XDD1 RS04365
gene id: 351671:XDD1_RS04365
uniprot id: A0A068QNV3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

351671:XDD1 RS03410
gene id: 351671:XDD1_RS03410
uniprot id: A0A068QN93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

351671:XDD1 RS13815
gene id: 351671:XDD1_RS13815
uniprot id: A0A068QV84
names: Similarity
messages: Belongs to the UPF0231 family.

351671:XDD1 RS04875
gene id: 351671:XDD1_RS04875
uniprot id: A0A068QP43
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS17040
gene id: 351671:XDD1_RS17040
uniprot id: A0A068QX67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
messages: Cytoplasm

351671:XDD1 RS18320
gene id: 351671:XDD1_RS18320
uniprot id: A0A068R0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Homodimer. Forms a complex with the accessory proteins ExbB and ExbD.
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

351671:XDD1 RS11120
gene id: 351671:XDD1_RS11120
uniprot id: A0A068QTX9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

351671:XDD1 RS12255
gene id: 351671:XDD1_RS12255
uniprot id: A0A068QTP7
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

351671:XDD1 RS12815
gene id: 351671:XDD1_RS12815
uniprot id: A0A068QTZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS12500
gene id: 351671:XDD1_RS12500
uniprot id: A0A068QX25
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS01640
gene id: 351671:XDD1_RS01640
uniprot id: A0A068QQC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

351671:XDD1 RS05880
gene id: 351671:XDD1_RS05880
uniprot id: A0A068QQN7
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

351671:XDD1 RS15755
gene id: 351671:XDD1_RS15755
uniprot id: A0A068QVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

351671:XDD1 RS08985
gene id: 351671:XDD1_RS08985
uniprot id: A0A068QUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

351671:XDD1 RS14445
gene id: 351671:XDD1_RS14445
uniprot id: A0A068QV37
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

351671:XDD1 RS05745
gene id: 351671:XDD1_RS05745
uniprot id: A0A068QQ56
names: Similarity
messages: Belongs to the IucA/IucC family.

351671:XDD1 RS00235
gene id: 351671:XDD1_RS00235
uniprot id: A0A068QLY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

351671:XDD1 RS01385
gene id: 351671:XDD1_RS01385
uniprot id: A0A068QME1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

351671:XDD1 RS04040
gene id: 351671:XDD1_RS04040
uniprot id: A0A068QP44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

351671:XDD1 RS14625
gene id: 351671:XDD1_RS14625
uniprot id: A0A068QVR3
names: Function
names: Similarity
messages: Belongs to the precorrin methyltransferase family.
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

351671:XDD1 RS07065
gene id: 351671:XDD1_RS07065
uniprot id: A0A068QRK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Homodimer.

351671:XDD1 RS10540
gene id: 351671:XDD1_RS10540
uniprot id: A0A068QVT4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

351671:XDD1 RS11525
gene id: 351671:XDD1_RS11525
uniprot id: A0A068QWF3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

351671:XDD1 RS02140
gene id: 351671:XDD1_RS02140
uniprot id: A0A068QML2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

351671:XDD1 RS01325
gene id: 351671:XDD1_RS01325
uniprot id: A0A068QN55
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

351671:XDD1 RS09365
gene id: 351671:XDD1_RS09365
uniprot id: A0A068QV80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS06705
gene id: 351671:XDD1_RS06705
uniprot id: A0A068QR73
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

351671:XDD1 RS04230
gene id: 351671:XDD1_RS04230
uniprot id: A0A068QPP3
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS14170
gene id: 351671:XDD1_RS14170
uniprot id: A0A068QUV1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS17810
gene id: 351671:XDD1_RS17810
uniprot id: A0A068QXZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

351671:XDD1 RS16100
gene id: 351671:XDD1_RS16100
uniprot id: A0A068QW44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS04865
gene id: 351671:XDD1_RS04865
uniprot id: A0A068QSH7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS14030
gene id: 351671:XDD1_RS14030
uniprot id: A0A068QUW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS14470
gene id: 351671:XDD1_RS14470
uniprot id: A0A068QV40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

351671:XDD1 RS10750
gene id: 351671:XDD1_RS10750
uniprot id: A0A068QTA6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

351671:XDD1 RS13050
gene id: 351671:XDD1_RS13050
uniprot id: A0A068QXD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351671:XDD1 RS02025
gene id: 351671:XDD1_RS02025
uniprot id: A0A068QQL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

351671:XDD1 RS14910
gene id: 351671:XDD1_RS14910
uniprot id: A0A068QVV6
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

351671:XDD1 RS08015
gene id: 351671:XDD1_RS08015
uniprot id: A0A068QS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

351671:XDD1 RS01440
gene id: 351671:XDD1_RS01440
uniprot id: A0A068QMU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

351671:XDD1 RS15675
gene id: 351671:XDD1_RS15675
uniprot id: A0A068QVQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

351671:XDD1 RS12140
gene id: 351671:XDD1_RS12140
uniprot id: A0A068QTM7
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.
messages: Cytoplasm

351671:XDD1 RS08645
gene id: 351671:XDD1_RS08645
uniprot id: A0A068QR91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

351671:XDD1 RS00515
gene id: 351671:XDD1_RS00515
uniprot id: A0A068QM39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

351671:XDD1 RS15060
gene id: 351671:XDD1_RS15060
uniprot id: A0A068QVB1
names: Similarity
messages: Belongs to the aspartokinase family.

351671:XDD1 RS16985
gene id: 351671:XDD1_RS16985
uniprot id: A0A068QZV4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

351671:XDD1 RS10945
gene id: 351671:XDD1_RS10945
uniprot id: A0A068QST1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

351671:XDD1 RS04635
gene id: 351671:XDD1_RS04635
uniprot id: A0A068QP17
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS08830
gene id: 351671:XDD1_RS08830
uniprot id: A0A068QS23
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

351671:XDD1 RS14475
gene id: 351671:XDD1_RS14475
uniprot id: A0A068QVN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS04015
gene id: 351671:XDD1_RS04015
uniprot id: A0A068QP40
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

351671:XDD1 RS05410
gene id: 351671:XDD1_RS05410
uniprot id: A0A068QSR5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

351671:XDD1 RS17755
gene id: 351671:XDD1_RS17755
uniprot id: A0A068R0A8
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS17465
gene id: 351671:XDD1_RS17465
uniprot id: A0A068QXE2
names: Similarity
messages: Belongs to the peptidase M16 family.

351671:XDD1 RS07150
gene id: 351671:XDD1_RS07150
uniprot id: A0A068QRL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

351671:XDD1 RS00765
gene id: 351671:XDD1_RS00765
uniprot id: A0A068QM67
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

351671:XDD1 RS13110
gene id: 351671:XDD1_RS13110
uniprot id: A0A068QU21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

351671:XDD1 RS11395
gene id: 351671:XDD1_RS11395
uniprot id: A0A068QT64
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

351671:XDD1 RS03960
gene id: 351671:XDD1_RS03960
uniprot id: A0A068QPI2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS08290
gene id: 351671:XDD1_RS08290
uniprot id: A0A068QR15
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

351671:XDD1 RS16225
gene id: 351671:XDD1_RS16225
uniprot id: A0A068QZF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

351671:XDD1 RS02090
gene id: 351671:XDD1_RS02090
uniprot id: A0A068QNJ0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351671:XDD1 RS10060
gene id: 351671:XDD1_RS10060
uniprot id: A0A068QVJ1
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS11460
gene id: 351671:XDD1_RS11460
uniprot id: A0A068QU70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

351671:XDD1 RS00085
gene id: 351671:XDD1_RS00085
uniprot id: A0A068QLW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

351671:XDD1 RS02055
gene id: 351671:XDD1_RS02055
uniprot id: A0A068QMP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

351671:XDD1 RS00555
gene id: 351671:XDD1_RS00555
uniprot id: A0A068QMT6
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12770
gene id: 351671:XDD1_RS12770
uniprot id: A0A068QUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M4 family.
messages: Extracellular zinc metalloprotease.
messages: Secreted

351671:XDD1 RS14320
gene id: 351671:XDD1_RS14320
uniprot id: A0A068QVZ6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

351671:XDD1 RS09075
gene id: 351671:XDD1_RS09075
uniprot id: A0A068QRQ7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

351671:XDD1 RS14850
gene id: 351671:XDD1_RS14850
uniprot id: A0A068QV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

351671:XDD1 RS05350
gene id: 351671:XDD1_RS05350
uniprot id: A0A068QPA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Monomer.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

351671:XDD1 RS06820
gene id: 351671:XDD1_RS06820
uniprot id: A0A068QRA5
names: Similarity
messages: Belongs to the MoaD family.

351671:XDD1 RS15140
gene id: 351671:XDD1_RS15140
uniprot id: A0A068QW02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS11970
gene id: 351671:XDD1_RS11970
uniprot id: A0A068QTJ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoB, CD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351671:XDD1 RS01915
gene id: 351671:XDD1_RS01915
uniprot id: A0A068QN19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

351671:XDD1 RS09080
gene id: 351671:XDD1_RS09080
uniprot id: A0A068QS99
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS08670
gene id: 351671:XDD1_RS08670
uniprot id: A0A068QR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS12320
gene id: 351671:XDD1_RS12320
uniprot id: A0A068QTQ9
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06725
gene id: 351671:XDD1_RS06725
uniprot id: A0A068QTH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

351671:XDD1 RS11190
gene id: 351671:XDD1_RS11190
uniprot id: A0A068QW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

351671:XDD1 RS14420
gene id: 351671:XDD1_RS14420
uniprot id: A0A068QV33
names: Subcellular Location Annotation
messages: Cell inner membrane

351671:XDD1 RS10410
gene id: 351671:XDD1_RS10410
uniprot id: A0A068QT24
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

351671:XDD1 RS09260
gene id: 351671:XDD1_RS09260
uniprot id: A0A068QRU6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

351671:XDD1 RS16600
gene id: 351671:XDD1_RS16600
uniprot id: A0A068QXC6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

351671:XDD1 RS00225
gene id: 351671:XDD1_RS00225
uniprot id: A0A068QPN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

351671:XDD1 RS05990
gene id: 351671:XDD1_RS05990
uniprot id: A0A068QQR4
names: Similarity
messages: Belongs to the PhoH family.

351671:XDD1 RS15485
gene id: 351671:XDD1_RS15485
uniprot id: A0A068QVK5
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

351671:XDD1 RS00275
gene id: 351671:XDD1_RS00275
uniprot id: A0A068QPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

351671:XDD1 RS16450
gene id: 351671:XDD1_RS16450
uniprot id: A0A068QW95
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

351671:XDD1 RS13025
gene id: 351671:XDD1_RS13025
uniprot id: A0A068QXC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS04195
gene id: 351671:XDD1_RS04195
uniprot id: A0A068QPN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS07100
gene id: 351671:XDD1_RS07100
uniprot id: A0A068QR53
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

351671:XDD1 RS02815
gene id: 351671:XDD1_RS02815
uniprot id: A0A068QNY4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

351671:XDD1 RS07055
gene id: 351671:XDD1_RS07055
uniprot id: A0A068QR42
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

351671:XDD1 RS06850
gene id: 351671:XDD1_RS06850
uniprot id: A0A068QQ54
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

351671:XDD1 RS09155
gene id: 351671:XDD1_RS09155
uniprot id: A0A068QSS4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

351671:XDD1 RS13660
gene id: 351671:XDD1_RS13660
uniprot id: A0A068QUJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

351671:XDD1 RS02270
gene id: 351671:XDD1_RS02270
uniprot id: A0A068QNN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

351671:XDD1 RS09470
gene id: 351671:XDD1_RS09470
uniprot id: A0A068QS18
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS01645
gene id: 351671:XDD1_RS01645
uniprot id: A0A068QNA8
names: Similarity
messages: Belongs to the thioredoxin family.

351671:XDD1 RS11450
gene id: 351671:XDD1_RS11450
uniprot id: A0A068QTS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

351671:XDD1 RS12800
gene id: 351671:XDD1_RS12800
uniprot id: A0A068QX81
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

351671:XDD1 RS06835
gene id: 351671:XDD1_RS06835
uniprot id: A0A068QQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

351671:XDD1 RS14350
gene id: 351671:XDD1_RS14350
uniprot id: A0A068QUY4
names: Similarity
messages: Belongs to the SfsA family.

351671:XDD1 RS12010
gene id: 351671:XDD1_RS12010
uniprot id: A0A068QUK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

351671:XDD1 RS03465
gene id: 351671:XDD1_RS03465
uniprot id: A0A068QNE9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS06180
gene id: 351671:XDD1_RS06180
uniprot id: A0A068QPN9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351671:XDD1 RS11945
gene id: 351671:XDD1_RS11945
uniprot id: A0A068QTJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

351671:XDD1 RS10620
gene id: 351671:XDD1_RS10620
uniprot id: A0A068QTM4
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

351671:XDD1 RS16475
gene id: 351671:XDD1_RS16475
uniprot id: A0A068QW96
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

351671:XDD1 RS03570
gene id: 351671:XDD1_RS03570
uniprot id: A0A068QRK4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

351671:XDD1 RS18330
gene id: 351671:XDD1_RS18330
uniprot id: A0A068QXB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

351671:XDD1 RS00985
gene id: 351671:XDD1_RS00985
uniprot id: A0A068QQ09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

351671:XDD1 RS07430
gene id: 351671:XDD1_RS07430
uniprot id: A0A068QRS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

351671:XDD1 RS16855
gene id: 351671:XDD1_RS16855
uniprot id: A0A068QX40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

351671:XDD1 RS16615
gene id: 351671:XDD1_RS16615
uniprot id: A0A068QX06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS04515
gene id: 351671:XDD1_RS04515
uniprot id: A0A068QS71
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS07940
gene id: 351671:XDD1_RS07940
uniprot id: A0A068QRZ1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05895
gene id: 351671:XDD1_RS05895
uniprot id: A0A068QT00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

351671:XDD1 RS14020
gene id: 351671:XDD1_RS14020
uniprot id: A0A068QVV0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS15720
gene id: 351671:XDD1_RS15720
uniprot id: A0A068QWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

351671:XDD1 RS17600
gene id: 351671:XDD1_RS17600
uniprot id: A0A068QWT1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06860
gene id: 351671:XDD1_RS06860
uniprot id: A0A068QQV9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

351671:XDD1 RS00295
gene id: 351671:XDD1_RS00295
uniprot id: A0A068QME7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS06355
gene id: 351671:XDD1_RS06355
uniprot id: A0A068QPT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

351671:XDD1 RS14610
gene id: 351671:XDD1_RS14610
uniprot id: A0A068QW46
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

351671:XDD1 RS01380
gene id: 351671:XDD1_RS01380
uniprot id: A0A068QMA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

351671:XDD1 RS17440
gene id: 351671:XDD1_RS17440
uniprot id: A0A068QXD8
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS13940
gene id: 351671:XDD1_RS13940
uniprot id: A0A068QXZ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

351671:XDD1 RS17815
gene id: 351671:XDD1_RS17815
uniprot id: A0A068QWY1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS02235
gene id: 351671:XDD1_RS02235
uniprot id: A0A068QNM8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

351671:XDD1 RS06265
gene id: 351671:XDD1_RS06265
uniprot id: A0A068QPR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

351671:XDD1 RS14705
gene id: 351671:XDD1_RS14705
uniprot id: A0A068QYI0
names: Similarity
messages: Belongs to the IMPACT family.

351671:XDD1 RS11390
gene id: 351671:XDD1_RS11390
uniprot id: A0A068QT36
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

351671:XDD1 RS10165
gene id: 351671:XDD1_RS10165
uniprot id: A0A068QSA6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

351671:XDD1 RS06385
gene id: 351671:XDD1_RS06385
uniprot id: A0A068QT89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

351671:XDD1 RS05420
gene id: 351671:XDD1_RS05420
uniprot id: A0A068QPB8
names: Similarity
messages: Belongs to the YkuD family.

351671:XDD1 RS05450
gene id: 351671:XDD1_RS05450
uniprot id: A0A068QQ15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

351671:XDD1 RS05515
gene id: 351671:XDD1_RS05515
uniprot id: A0A068QPD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
messages: Cell membrane
messages: Homotetramer.
messages: Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine.

351671:XDD1 RS08300
gene id: 351671:XDD1_RS08300
uniprot id: A0A068QRR9
names: Similarity
messages: Belongs to the darcynin family.

351671:XDD1 RS15620
gene id: 351671:XDD1_RS15620
uniprot id: A0A068QWA3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

351671:XDD1 RS08550
gene id: 351671:XDD1_RS08550
uniprot id: A0A068QRW3
names: Similarity
messages: Belongs to the pyruvate kinase family.

351671:XDD1 RS10670
gene id: 351671:XDD1_RS10670
uniprot id: A0A068QSP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

351671:XDD1 RS03725
gene id: 351671:XDD1_RS03725
uniprot id: A0A068QNJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

351671:XDD1 RS02605
gene id: 351671:XDD1_RS02605
uniprot id: A0A068QMX4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351671:XDD1 RS14765
gene id: 351671:XDD1_RS14765
uniprot id: A0A068QV56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

351671:XDD1 RS13790
gene id: 351671:XDD1_RS13790
uniprot id: A0A068QUM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

351671:XDD1 RS11415
gene id: 351671:XDD1_RS11415
uniprot id: A0A068QT43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

351671:XDD1 RS06645
gene id: 351671:XDD1_RS06645
uniprot id: A0A068QQQ5
names: Similarity
messages: Belongs to the Dps family.

351671:XDD1 RS01600
gene id: 351671:XDD1_RS01600
uniprot id: A0A068QMC2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01370
gene id: 351671:XDD1_RS01370
uniprot id: A0A068QQ77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

351671:XDD1 RS17735
gene id: 351671:XDD1_RS17735
uniprot id: A0A068QXX3
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

351671:XDD1 RS08230
gene id: 351671:XDD1_RS08230
uniprot id: A0A068QRQ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArnF family.
messages: Cell inner membrane
messages: Heterodimer of ArnE and ArnF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.

351671:XDD1 RS07380
gene id: 351671:XDD1_RS07380
uniprot id: A0A068QRR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapC family.
messages: Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
messages: Cytoplasm
messages: Interacts directly with FtsZ.

351671:XDD1 RS04110
gene id: 351671:XDD1_RS04110
uniprot id: A0A068QPL2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

351671:XDD1 RS12905
gene id: 351671:XDD1_RS12905
uniprot id: A0A068QUZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

351671:XDD1 RS00345
gene id: 351671:XDD1_RS00345
uniprot id: A0A068QMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS09715
gene id: 351671:XDD1_RS09715
uniprot id: A0A068QS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fimbrial export usher family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS15050
gene id: 351671:XDD1_RS15050
uniprot id: A0A068QYN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Monomer.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

351671:XDD1 RS08335
gene id: 351671:XDD1_RS08335
uniprot id: A0A068QRS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351671:XDD1 RS10915
gene id: 351671:XDD1_RS10915
uniprot id: A0A068QTT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS00375
gene id: 351671:XDD1_RS00375
uniprot id: A0A068QLY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Monomer.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

351671:XDD1 RS10470
gene id: 351671:XDD1_RS10470
uniprot id: A0A068QT42
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

351671:XDD1 RS11325
gene id: 351671:XDD1_RS11325
uniprot id: A0A068QT47
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01750
gene id: 351671:XDD1_RS01750
uniprot id: A0A068QQE9
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

351671:XDD1 RS04360
gene id: 351671:XDD1_RS04360
uniprot id: A0A068QNR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

351671:XDD1 RS05430
gene id: 351671:XDD1_RS05430
uniprot id: A0A068QSR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

351671:XDD1 RS15330
gene id: 351671:XDD1_RS15330
uniprot id: A0A068QW43
names: Similarity
messages: Belongs to the acetyltransferase YopJ family.

351671:XDD1 RS18265
gene id: 351671:XDD1_RS18265
uniprot id: A0A068QXF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

351671:XDD1 RS15045
gene id: 351671:XDD1_RS15045
uniprot id: A0A068QVY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

351671:XDD1 RS05345
gene id: 351671:XDD1_RS05345
uniprot id: A0A068QQE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

351671:XDD1 RS08100
gene id: 351671:XDD1_RS08100
uniprot id: A0A068QQY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS00440
gene id: 351671:XDD1_RS00440
uniprot id: A0A068QPR0
names: Similarity
messages: Belongs to the HSP15 family.

351671:XDD1 RS00250
gene id: 351671:XDD1_RS00250
uniprot id: A0A068QPN5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05520
gene id: 351671:XDD1_RS05520
uniprot id: A0A068QPI3
names: Function
names: Similarity
messages: Belongs to the FrsA family.
messages: Catalyzes the hydrolysis of esters.

351671:XDD1 RS00220
gene id: 351671:XDD1_RS00220
uniprot id: A0A068QMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

351671:XDD1 RS08940
gene id: 351671:XDD1_RS08940
uniprot id: A0A068QS56
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
messages: Reaction proceeds via an anti dehydration.

351671:XDD1 RS03245
gene id: 351671:XDD1_RS03245
uniprot id: A0A068QNB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS12595
gene id: 351671:XDD1_RS12595
uniprot id: A0A068QUF8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

351671:XDD1 RS08210
gene id: 351671:XDD1_RS08210
uniprot id: A0A068QUE2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Homohexamer, formed by a dimer of trimers.
messages: In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS12880
gene id: 351671:XDD1_RS12880
uniprot id: A0A068QUZ3
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

351671:XDD1 RS00080
gene id: 351671:XDD1_RS00080
uniprot id: A0A068QMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

351671:XDD1 RS15560
gene id: 351671:XDD1_RS15560
uniprot id: A0A068QVM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

351671:XDD1 RS08125
gene id: 351671:XDD1_RS08125
uniprot id: A0A068QQY7
names: Similarity
messages: Belongs to the intimin/invasin family.

351671:XDD1 RS16285
gene id: 351671:XDD1_RS16285
uniprot id: A0A068QW42
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12090
gene id: 351671:XDD1_RS12090
uniprot id: A0A068QTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS15715
gene id: 351671:XDD1_RS15715
uniprot id: A0A068QZ37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

351671:XDD1 RS03910
gene id: 351671:XDD1_RS03910
uniprot id: A0A068QPH2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

351671:XDD1 RS08705
gene id: 351671:XDD1_RS08705
uniprot id: A0A068QRZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

351671:XDD1 RS00590
gene id: 351671:XDD1_RS00590
uniprot id: A0A068QM47
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

351671:XDD1 RS12275
gene id: 351671:XDD1_RS12275
uniprot id: A0A068QTM6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS14700
gene id: 351671:XDD1_RS14700
uniprot id: A0A068QVS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

351671:XDD1 RS11150
gene id: 351671:XDD1_RS11150
uniprot id: A0A068QSX5
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

351671:XDD1 RS04630
gene id: 351671:XDD1_RS04630
uniprot id: A0A068QNX3
names: Similarity
messages: Belongs to the phosphoglycerate kinase family.

351671:XDD1 RS04200
gene id: 351671:XDD1_RS04200
uniprot id: A0A068QNN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

351671:XDD1 RS03885
gene id: 351671:XDD1_RS03885
uniprot id: A0A068QPG6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

351671:XDD1 RS00630
gene id: 351671:XDD1_RS00630
uniprot id: A0A068QPU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

351671:XDD1 RS04380
gene id: 351671:XDD1_RS04380
uniprot id: A0A068QS33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS07200
gene id: 351671:XDD1_RS07200
uniprot id: A0A068QQH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

351671:XDD1 RS09265
gene id: 351671:XDD1_RS09265
uniprot id: A0A068QSE1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

351671:XDD1 RS14315
gene id: 351671:XDD1_RS14315
uniprot id: A0A068QYB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS01005
gene id: 351671:XDD1_RS01005
uniprot id: A0A068QMM6
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

351671:XDD1 RS05850
gene id: 351671:XDD1_RS05850
uniprot id: A0A068QSZ3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

351671:XDD1 RS08665
gene id: 351671:XDD1_RS08665
uniprot id: A0A068QSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS07275
gene id: 351671:XDD1_RS07275
uniprot id: A0A068QR87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

351671:XDD1 RS11995
gene id: 351671:XDD1_RS11995
uniprot id: A0A068QTK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS10685
gene id: 351671:XDD1_RS10685
uniprot id: A0A068QTP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

351671:XDD1 RS07025
gene id: 351671:XDD1_RS07025
uniprot id: A0A068QQB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

351671:XDD1 RS05930
gene id: 351671:XDD1_RS05930
uniprot id: A0A068QPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS13545
gene id: 351671:XDD1_RS13545
uniprot id: A0A068QXQ1
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

351671:XDD1 RS16220
gene id: 351671:XDD1_RS16220
uniprot id: A0A068QWP5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

351671:XDD1 RS10315
gene id: 351671:XDD1_RS10315
uniprot id: A0A068QVN9
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

351671:XDD1 RS01665
gene id: 351671:XDD1_RS01665
uniprot id: A0A068QNB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
messages: Catalyzes the reversible epimerization at C-2 of UDP-N-acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS12240
gene id: 351671:XDD1_RS12240
uniprot id: A0A068QWY0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS15335
gene id: 351671:XDD1_RS15335
uniprot id: A0A068QYU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS11215
gene id: 351671:XDD1_RS11215
uniprot id: A0A068QW72
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

351671:XDD1 RS01030
gene id: 351671:XDD1_RS01030
uniprot id: A0A068QQ17
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS09700
gene id: 351671:XDD1_RS09700
uniprot id: A0A068QSQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

351671:XDD1 RS00210
gene id: 351671:XDD1_RS00210
uniprot id: A0A068QLX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

351671:XDD1 RS04985
gene id: 351671:XDD1_RS04985
uniprot id: A0A068QPT8
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS05670
gene id: 351671:XDD1_RS05670
uniprot id: A0A068QQJ8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

351671:XDD1 RS05435
gene id: 351671:XDD1_RS05435
uniprot id: A0A068QQG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

351671:XDD1 RS10110
gene id: 351671:XDD1_RS10110
uniprot id: A0A068QVK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

351671:XDD1 RS14845
gene id: 351671:XDD1_RS14845
uniprot id: A0A068QW76
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

351671:XDD1 RS13005
gene id: 351671:XDD1_RS13005
uniprot id: A0A068QV20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

351671:XDD1 RS04240
gene id: 351671:XDD1_RS04240
uniprot id: A0A068QNT2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

351671:XDD1 RS14760
gene id: 351671:XDD1_RS14760
uniprot id: A0A068QW63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS08730
gene id: 351671:XDD1_RS08730
uniprot id: A0A068QRH2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

351671:XDD1 RS04030
gene id: 351671:XDD1_RS04030
uniprot id: A0A068QNJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

351671:XDD1 RS02200
gene id: 351671:XDD1_RS02200
uniprot id: A0A068QMS7
names: Similarity
messages: Belongs to the RelE toxin family.

351671:XDD1 RS09640
gene id: 351671:XDD1_RS09640
uniprot id: A0A068QT46
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

351671:XDD1 RS13875
gene id: 351671:XDD1_RS13875
uniprot id: A0A068QUQ2
names: Similarity
messages: Belongs to the GSP E family.

351671:XDD1 RS02060
gene id: 351671:XDD1_RS02060
uniprot id: A0A068QN49
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

351671:XDD1 RS11575
gene id: 351671:XDD1_RS11575
uniprot id: A0A068QWG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

351671:XDD1 RS09255
gene id: 351671:XDD1_RS09255
uniprot id: A0A068QRP4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

351671:XDD1 RS16530
gene id: 351671:XDD1_RS16530
uniprot id: A0A068QXB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

351671:XDD1 RS09135
gene id: 351671:XDD1_RS09135
uniprot id: A0A068QUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS04270
gene id: 351671:XDD1_RS04270
uniprot id: A0A068QPA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

351671:XDD1 RS11695
gene id: 351671:XDD1_RS11695
uniprot id: A0A068QTD0
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

351671:XDD1 RS03575
gene id: 351671:XDD1_RS03575
uniprot id: A0A068QPA5
names: Similarity
messages: Belongs to the thioesterase family.

351671:XDD1 RS10175
gene id: 351671:XDD1_RS10175
uniprot id: A0A068QVL3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS10250
gene id: 351671:XDD1_RS10250
uniprot id: A0A068QTE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0259 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS15570
gene id: 351671:XDD1_RS15570
uniprot id: A0A068QW91
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

351671:XDD1 RS11355
gene id: 351671:XDD1_RS11355
uniprot id: A0A068QTQ5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS04715
gene id: 351671:XDD1_RS04715
uniprot id: A0A068QQ42
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS02180
gene id: 351671:XDD1_RS02180
uniprot id: A0A068QMM0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

351671:XDD1 RS07375
gene id: 351671:XDD1_RS07375
uniprot id: A0A068QTZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

351671:XDD1 RS13075
gene id: 351671:XDD1_RS13075
uniprot id: A0A068QXE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

351671:XDD1 RS16860
gene id: 351671:XDD1_RS16860
uniprot id: A0A068QZT3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351671:XDD1 RS01695
gene id: 351671:XDD1_RS01695
uniprot id: A0A068QMD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.
messages: Cell inner membrane
messages: Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
messages: Membrane
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

351671:XDD1 RS15440
gene id: 351671:XDD1_RS15440
uniprot id: A0A068QVJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

351671:XDD1 RS01445
gene id: 351671:XDD1_RS01445
uniprot id: A0A068QQ94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

351671:XDD1 RS10020
gene id: 351671:XDD1_RS10020
uniprot id: A0A068QS80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS06480
gene id: 351671:XDD1_RS06480
uniprot id: A0A068QPW4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS12475
gene id: 351671:XDD1_RS12475
uniprot id: A0A068QTR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS17065
gene id: 351671:XDD1_RS17065
uniprot id: A0A068QX72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

351671:XDD1 RS16960
gene id: 351671:XDD1_RS16960
uniprot id: A0A068QZV1
names: Similarity
messages: Belongs to the UPF0270 family.

351671:XDD1 RS01630
gene id: 351671:XDD1_RS01630
uniprot id: A0A068QMH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

351671:XDD1 RS09765
gene id: 351671:XDD1_RS09765
uniprot id: A0A068QSR2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

351671:XDD1 RS14285
gene id: 351671:XDD1_RS14285
uniprot id: A0A068QV82
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS15760
gene id: 351671:XDD1_RS15760
uniprot id: A0A068QWD9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

351671:XDD1 RS04115
gene id: 351671:XDD1_RS04115
uniprot id: A0A068QNL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

351671:XDD1 RS08295
gene id: 351671:XDD1_RS08295
uniprot id: A0A068QR83
names: Similarity
messages: Belongs to the thioesterase family.

351671:XDD1 RS11715
gene id: 351671:XDD1_RS11715
uniprot id: A0A068QUG1
names: Similarity
messages: Belongs to the UPF0352 family.

351671:XDD1 RS00280
gene id: 351671:XDD1_RS00280
uniprot id: A0A068QMQ5
names: Similarity
names: Subunit
messages: Belongs to the ViaA family.
messages: Possible formation of a ternary complex RavA-ViaA-CadA.

351671:XDD1 RS18215
gene id: 351671:XDD1_RS18215
uniprot id: A0A068QXD3
names: Similarity
messages: Belongs to the colicins ColE2/ColE8/ColE9 and pyocins S1/S2 family.

351671:XDD1 RS11850
gene id: 351671:XDD1_RS11850
uniprot id: A0A068QTH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

351671:XDD1 RS14010
gene id: 351671:XDD1_RS14010
uniprot id: A0A068QVF9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

351671:XDD1 RS09595
gene id: 351671:XDD1_RS09595
uniprot id: A0A068QS02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS11935
gene id: 351671:XDD1_RS11935
uniprot id: A0A068QUJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351671:XDD1 RS03305
gene id: 351671:XDD1_RS03305
uniprot id: A0A068QRF9
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06545
gene id: 351671:XDD1_RS06545
uniprot id: A0A068QR28
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS07255
gene id: 351671:XDD1_RS07255
uniprot id: A0A068QR82
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS15730
gene id: 351671:XDD1_RS15730
uniprot id: A0A068QVV3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

351671:XDD1 RS05790
gene id: 351671:XDD1_RS05790
uniprot id: A0A068QQ65
names: Similarity
messages: Belongs to the IucA/IucC family.

351671:XDD1 RS05575
gene id: 351671:XDD1_RS05575
uniprot id: A0A068QQ33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

351671:XDD1 RS05625
gene id: 351671:XDD1_RS05625
uniprot id: A0A068QQI8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

351671:XDD1 RS10040
gene id: 351671:XDD1_RS10040
uniprot id: A0A068QTA7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS02290
gene id: 351671:XDD1_RS02290
uniprot id: A0A068QQT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

351671:XDD1 RS03715
gene id: 351671:XDD1_RS03715
uniprot id: A0A068QPD4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351671:XDD1 RS15565
gene id: 351671:XDD1_RS15565
uniprot id: A0A068QVR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

351671:XDD1 RS03745
gene id: 351671:XDD1_RS03745
uniprot id: A0A068QNE3
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

351671:XDD1 RS11920
gene id: 351671:XDD1_RS11920
uniprot id: A0A068QTJ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: Membrane

351671:XDD1 RS02150
gene id: 351671:XDD1_RS02150
uniprot id: A0A068QQP5
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

351671:XDD1 RS03840
gene id: 351671:XDD1_RS03840
uniprot id: A0A068QRQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

351671:XDD1 RS15025
gene id: 351671:XDD1_RS15025
uniprot id: A0A068QYN2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS12085
gene id: 351671:XDD1_RS12085
uniprot id: A0A068QTJ1
names: Similarity
messages: Belongs to the MlaA family.

351671:XDD1 RS02135
gene id: 351671:XDD1_RS02135
uniprot id: A0A068QNK2
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.

351671:XDD1 RS02510
gene id: 351671:XDD1_RS02510
uniprot id: A0A068QR17
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

351671:XDD1 RS04225
gene id: 351671:XDD1_RS04225
uniprot id: A0A068QRZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

351671:XDD1 RS11585
gene id: 351671:XDD1_RS11585
uniprot id: A0A068QT93
names: Similarity
messages: Belongs to the UPF0265 family.

351671:XDD1 RS00830
gene id: 351671:XDD1_RS00830
uniprot id: A0A068QM30
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351671:XDD1 RS17730
gene id: 351671:XDD1_RS17730
uniprot id: A0A068R0A3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS02165
gene id: 351671:XDD1_RS02165
uniprot id: A0A068QN73
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS03110
gene id: 351671:XDD1_RS03110
uniprot id: A0A068QRB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

351671:XDD1 RS14045
gene id: 351671:XDD1_RS14045
uniprot id: A0A068QUT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

351671:XDD1 RS03275
gene id: 351671:XDD1_RS03275
uniprot id: A0A068QN71
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

351671:XDD1 RS13675
gene id: 351671:XDD1_RS13675
uniprot id: A0A068QUG6
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

351671:XDD1 RS12660
gene id: 351671:XDD1_RS12660
uniprot id: A0A068QUH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

351671:XDD1 RS12340
gene id: 351671:XDD1_RS12340
uniprot id: A0A068QTP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

351671:XDD1 RS10260
gene id: 351671:XDD1_RS10260
uniprot id: A0A068QSF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

351671:XDD1 RS05330
gene id: 351671:XDD1_RS05330
uniprot id: A0A068QPF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351671:XDD1 RS08220
gene id: 351671:XDD1_RS08220
uniprot id: A0A068QR04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 83 family.
messages: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

351671:XDD1 RS14485
gene id: 351671:XDD1_RS14485
uniprot id: A0A068QW22
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

351671:XDD1 RS16070
gene id: 351671:XDD1_RS16070
uniprot id: A0A068QWY4
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01845
gene id: 351671:XDD1_RS01845
uniprot id: A0A068QML0
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS00915
gene id: 351671:XDD1_RS00915
uniprot id: A0A068QPZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

351671:XDD1 RS06815
gene id: 351671:XDD1_RS06815
uniprot id: A0A068QTJ7
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

351671:XDD1 RS10130
gene id: 351671:XDD1_RS10130
uniprot id: A0A068QSX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

351671:XDD1 RS04250
gene id: 351671:XDD1_RS04250
uniprot id: A0A068QRZ9
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

351671:XDD1 RS06205
gene id: 351671:XDD1_RS06205
uniprot id: A0A068QPP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

351671:XDD1 RS12900
gene id: 351671:XDD1_RS12900
uniprot id: A0A068QXA0
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

351671:XDD1 RS05875
gene id: 351671:XDD1_RS05875
uniprot id: A0A068QSZ7
names: Similarity
messages: Belongs to the UPF0250 family.

351671:XDD1 RS11560
gene id: 351671:XDD1_RS11560
uniprot id: A0A068QT86
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

351671:XDD1 RS13030
gene id: 351671:XDD1_RS13030
uniprot id: A0A068QV26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

351671:XDD1 RS17490
gene id: 351671:XDD1_RS17490
uniprot id: A0A068QXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS10845
gene id: 351671:XDD1_RS10845
uniprot id: A0A068QTC1
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

351671:XDD1 RS08110
gene id: 351671:XDD1_RS08110
uniprot id: A0A068QRN4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

351671:XDD1 RS05160
gene id: 351671:XDD1_RS05160
uniprot id: A0A068QQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

351671:XDD1 RS03610
gene id: 351671:XDD1_RS03610
uniprot id: A0A068QNW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

351671:XDD1 RS07250
gene id: 351671:XDD1_RS07250
uniprot id: A0A068QQQ0
names: Similarity
messages: Belongs to the asparaginase 1 family.

351671:XDD1 RS00680
gene id: 351671:XDD1_RS00680
uniprot id: A0A068QMV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

351671:XDD1 RS05600
gene id: 351671:XDD1_RS05600
uniprot id: A0A068QQI5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

351671:XDD1 RS05340
gene id: 351671:XDD1_RS05340
uniprot id: A0A068QSQ2
names: Similarity
messages: Belongs to the YggT family.

351671:XDD1 RS03035
gene id: 351671:XDD1_RS03035
uniprot id: A0A068QRA6
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS04170
gene id: 351671:XDD1_RS04170
uniprot id: A0A068QRX9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS15370
gene id: 351671:XDD1_RS15370
uniprot id: A0A068QW52
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10B family.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS13730
gene id: 351671:XDD1_RS13730
uniprot id: A0A068QUL1
names: Similarity
messages: Belongs to the NodU/CmcH family.

351671:XDD1 RS16330
gene id: 351671:XDD1_RS16330
uniprot id: A0A068QX69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RapZ-like family. RapZ subfamily.
messages: Homotrimer.
messages: Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.

351671:XDD1 RS06365
gene id: 351671:XDD1_RS06365
uniprot id: A0A068QQH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

351671:XDD1 RS01710
gene id: 351671:XDD1_RS01710
uniprot id: A0A068QQE3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family.
messages: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.

351671:XDD1 RS05360
gene id: 351671:XDD1_RS05360
uniprot id: A0A068QPZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

351671:XDD1 RS13945
gene id: 351671:XDD1_RS13945
uniprot id: A0A068QVR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

351671:XDD1 RS10255
gene id: 351671:XDD1_RS10255
uniprot id: A0A068QSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

351671:XDD1 RS16805
gene id: 351671:XDD1_RS16805
uniprot id: A0A068QZS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

351671:XDD1 RS16305
gene id: 351671:XDD1_RS16305
uniprot id: A0A068QX49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

351671:XDD1 RS13965
gene id: 351671:XDD1_RS13965
uniprot id: A0A068QY18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS16480
gene id: 351671:XDD1_RS16480
uniprot id: A0A068QWE8
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

351671:XDD1 RS14885
gene id: 351671:XDD1_RS14885
uniprot id: A0A068QVV2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

351671:XDD1 RS16900
gene id: 351671:XDD1_RS16900
uniprot id: A0A068QWK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DsrF/TusC family.
messages: Cytoplasm
messages: Heterohexamer, formed by a dimer of trimers. The hexameric TusBCD complex contains 2 copies each of TusB, TusC and TusD. The TusBCD complex interacts with TusE.
messages: Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.

351671:XDD1 RS16255
gene id: 351671:XDD1_RS16255
uniprot id: A0A068QX37
names: Similarity
messages: Belongs to the BolA/IbaG family.

351671:XDD1 RS14530
gene id: 351671:XDD1_RS14530
uniprot id: A0A068QW29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS10785
gene id: 351671:XDD1_RS10785
uniprot id: A0A068QTR1
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

351671:XDD1 RS11805
gene id: 351671:XDD1_RS11805
uniprot id: A0A068QWR6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RcsB family.
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.
messages: Interacts with RcsD.
messages: Phosphorylated and activated by RcsD.

351671:XDD1 RS15625
gene id: 351671:XDD1_RS15625
uniprot id: A0A068QWN3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

351671:XDD1 RS15220
gene id: 351671:XDD1_RS15220
uniprot id: A0A068QWE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

351671:XDD1 RS00380
gene id: 351671:XDD1_RS00380
uniprot id: A0A068QM27
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

351671:XDD1 RS02990
gene id: 351671:XDD1_RS02990
uniprot id: A0A068QP09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

351671:XDD1 RS10780
gene id: 351671:XDD1_RS10780
uniprot id: A0A068QVY3
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

351671:XDD1 RS08190
gene id: 351671:XDD1_RS08190
uniprot id: A0A068QS47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351671:XDD1 RS06580
gene id: 351671:XDD1_RS06580
uniprot id: A0A068QQ55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

351671:XDD1 RS09275
gene id: 351671:XDD1_RS09275
uniprot id: A0A068QSV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

351671:XDD1 RS13975
gene id: 351671:XDD1_RS13975
uniprot id: A0A068QUR2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS03530
gene id: 351671:XDD1_RS03530
uniprot id: A0A068QNB1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

351671:XDD1 RS04660
gene id: 351671:XDD1_RS04660
uniprot id: A0A068QP20
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351671:XDD1 RS16570
gene id: 351671:XDD1_RS16570
uniprot id: A0A068QZN9
names: Cofactor
names: Similarity
messages: Belongs to the iron-containing alcohol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS15450
gene id: 351671:XDD1_RS15450
uniprot id: A0A068QYX6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

351671:XDD1 RS12015
gene id: 351671:XDD1_RS12015
uniprot id: A0A068QTH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

351671:XDD1 RS01230
gene id: 351671:XDD1_RS01230
uniprot id: A0A068QN41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

351671:XDD1 RS02155
gene id: 351671:XDD1_RS02155
uniprot id: A0A068QNK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

351671:XDD1 RS03780
gene id: 351671:XDD1_RS03780
uniprot id: A0A068QP00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS10840
gene id: 351671:XDD1_RS10840
uniprot id: A0A068QSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS10420
gene id: 351671:XDD1_RS10420
uniprot id: A0A068QTH5
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

351671:XDD1 RS12895
gene id: 351671:XDD1_RS12895
uniprot id: A0A068QUM1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 2 iron ions per dimer. The dimer may bind additional iron ions.
messages: Homodimer; may form tetramers and higher multimers.
messages: Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.

351671:XDD1 RS06615
gene id: 351671:XDD1_RS06615
uniprot id: A0A068QR45
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

351671:XDD1 RS16425
gene id: 351671:XDD1_RS16425
uniprot id: A0A068QX96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

351671:XDD1 RS15610
gene id: 351671:XDD1_RS15610
uniprot id: A0A068QVN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

351671:XDD1 RS17980
gene id: 351671:XDD1_RS17980
uniprot id: A0A068QXP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Cell membrane
messages: Membrane
messages: Rhomboid-type serine protease that catalyzes intramembrane proteolysis.

351671:XDD1 RS02750
gene id: 351671:XDD1_RS02750
uniprot id: A0A068QN47
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

351671:XDD1 RS14815
gene id: 351671:XDD1_RS14815
uniprot id: A0A068QV63
names: Similarity
messages: Belongs to the hyi family.

351671:XDD1 RS18255
gene id: 351671:XDD1_RS18255
uniprot id: A0A068R0M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

351671:XDD1 RS16635
gene id: 351671:XDD1_RS16635
uniprot id: A0A068QWH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

351671:XDD1 RS10935
gene id: 351671:XDD1_RS10935
uniprot id: A0A068QW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

351671:XDD1 RS17585
gene id: 351671:XDD1_RS17585
uniprot id: A0A068QXG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351671:XDD1 RS07970
gene id: 351671:XDD1_RS07970
uniprot id: A0A068QQV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0266 family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS12860
gene id: 351671:XDD1_RS12860
uniprot id: A0A068QTX6
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

351671:XDD1 RS03540
gene id: 351671:XDD1_RS03540
uniprot id: A0A068QNV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

351671:XDD1 RS03850
gene id: 351671:XDD1_RS03850
uniprot id: A0A068QNL1
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

351671:XDD1 RS01235
gene id: 351671:XDD1_RS01235
uniprot id: A0A068QM85
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.

351671:XDD1 RS16340
gene id: 351671:XDD1_RS16340
uniprot id: A0A068QWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Amino-acid racemase able to utilize a broad range of substrates.
messages: Belongs to the alanine racemase family. Bsr subfamily.
messages: Periplasm

351671:XDD1 RS18250
gene id: 351671:XDD1_RS18250
uniprot id: A0A068QXW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers. Binds only one seryl-tRNA(Sec) per dimer.

351671:XDD1 RS01670
gene id: 351671:XDD1_RS01670
uniprot id: A0A068QMD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily.
messages: Catalyzes the four-electron oxidation of UDP-N-acetyl-D-mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA).
messages: Homodimer.

351671:XDD1 RS09530
gene id: 351671:XDD1_RS09530
uniprot id: A0A068QS28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

351671:XDD1 RS03855
gene id: 351671:XDD1_RS03855
uniprot id: A0A068QP11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

351671:XDD1 RS01575
gene id: 351671:XDD1_RS01575
uniprot id: A0A068QMC0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

351671:XDD1 RS18365
gene id: 351671:XDD1_RS18365
uniprot id: A0A068QNV6
names: Similarity
messages: Belongs to the intimin/invasin family.

351671:XDD1 RS04545
gene id: 351671:XDD1_RS04545
uniprot id: A0A068QNU8
names: Similarity
messages: Belongs to the transglycosylase Slt family.

351671:XDD1 RS03710
gene id: 351671:XDD1_RS03710
uniprot id: A0A068QRN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS09095
gene id: 351671:XDD1_RS09095
uniprot id: A0A068QRK2
names: Similarity
messages: Belongs to the IucA/IucC family.

351671:XDD1 RS03450
gene id: 351671:XDD1_RS03450
uniprot id: A0A068QRI2
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

351671:XDD1 RS07990
gene id: 351671:XDD1_RS07990
uniprot id: A0A068QS00
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

351671:XDD1 RS17745
gene id: 351671:XDD1_RS17745
uniprot id: A0A068QX26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS14650
gene id: 351671:XDD1_RS14650
uniprot id: A0A068QYH5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS18315
gene id: 351671:XDD1_RS18315
uniprot id: A0A068QXX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS16135
gene id: 351671:XDD1_RS16135
uniprot id: A0A068QZD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

351671:XDD1 RS15685
gene id: 351671:XDD1_RS15685
uniprot id: A0A068QWB9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

351671:XDD1 RS03865
gene id: 351671:XDD1_RS03865
uniprot id: A0A068QPG3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

351671:XDD1 RS17580
gene id: 351671:XDD1_RS17580
uniprot id: A0A068QWY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

351671:XDD1 RS14920
gene id: 351671:XDD1_RS14920
uniprot id: A0A068QW90
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

351671:XDD1 RS07325
gene id: 351671:XDD1_RS07325
uniprot id: A0A068QR95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

351671:XDD1 RS10380
gene id: 351671:XDD1_RS10380
uniprot id: A0A068QSG9
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

351671:XDD1 RS17990
gene id: 351671:XDD1_RS17990
uniprot id: A0A068QY32
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

351671:XDD1 RS09645
gene id: 351671:XDD1_RS09645
uniprot id: A0A068QS08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

351671:XDD1 RS17055
gene id: 351671:XDD1_RS17055
uniprot id: A0A068QWI3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS16835
gene id: 351671:XDD1_RS16835
uniprot id: A0A068QZS9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351671:XDD1 RS00455
gene id: 351671:XDD1_RS00455
uniprot id: A0A068QM33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS10740
gene id: 351671:XDD1_RS10740
uniprot id: A0A068QSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

351671:XDD1 RS03010
gene id: 351671:XDD1_RS03010
uniprot id: A0A068QRA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

351671:XDD1 RS07020
gene id: 351671:XDD1_RS07020
uniprot id: A0A068QRG7
names: Similarity
messages: Belongs to the UPF0053 family.

351671:XDD1 RS15155
gene id: 351671:XDD1_RS15155
uniprot id: A0A068QVG6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

351671:XDD1 RS16295
gene id: 351671:XDD1_RS16295
uniprot id: A0A068QWR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

351671:XDD1 RS09925
gene id: 351671:XDD1_RS09925
uniprot id: A0A068QVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS11795
gene id: 351671:XDD1_RS11795
uniprot id: A0A068QTH2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351671:XDD1 RS07160
gene id: 351671:XDD1_RS07160
uniprot id: A0A068QQN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

351671:XDD1 RS02395
gene id: 351671:XDD1_RS02395
uniprot id: A0A068QNC2
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

351671:XDD1 RS14875
gene id: 351671:XDD1_RS14875
uniprot id: A0A068QV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

351671:XDD1 RS11630
gene id: 351671:XDD1_RS11630
uniprot id: A0A068QUD2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS15150
gene id: 351671:XDD1_RS15150
uniprot id: A0A068QVC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RcsF family.
messages: Cell outer membrane
messages: Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS13805
gene id: 351671:XDD1_RS13805
uniprot id: A0A068QUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysE/ArgO transporter (TC 2.A.75) family.
messages: Cell membrane
messages: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine.

351671:XDD1 RS09245
gene id: 351671:XDD1_RS09245
uniprot id: A0A068QV22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Homodimer.

351671:XDD1 RS11680
gene id: 351671:XDD1_RS11680
uniprot id: A0A068QU23
names: Similarity
messages: Belongs to the peptidase C40 family.

351671:XDD1 RS14895
gene id: 351671:XDD1_RS14895
uniprot id: A0A068QW84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

351671:XDD1 RS02295
gene id: 351671:XDD1_RS02295
uniprot id: A0A068QNN8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Homodimer.
messages: May be involved in cell division.

351671:XDD1 RS01435
gene id: 351671:XDD1_RS01435
uniprot id: A0A068QME9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

351671:XDD1 RS16095
gene id: 351671:XDD1_RS16095
uniprot id: A0A068QVZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

351671:XDD1 RS07215
gene id: 351671:XDD1_RS07215
uniprot id: A0A068QTX0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS09480
gene id: 351671:XDD1_RS09480
uniprot id: A0A068QT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

351671:XDD1 RS05380
gene id: 351671:XDD1_RS05380
uniprot id: A0A068QQ01
names: Similarity
messages: Belongs to the peptidase A24 family.

351671:XDD1 RS15200
gene id: 351671:XDD1_RS15200
uniprot id: A0A068QVD5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

351671:XDD1 RS03655
gene id: 351671:XDD1_RS03655
uniprot id: A0A068QNX8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

351671:XDD1 RS09270
gene id: 351671:XDD1_RS09270
uniprot id: A0A068QV28
names: Similarity
messages: Belongs to the UPF0162 family.

351671:XDD1 RS15520
gene id: 351671:XDD1_RS15520
uniprot id: A0A068QVL1
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

351671:XDD1 RS13970
gene id: 351671:XDD1_RS13970
uniprot id: A0A068QVS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

351671:XDD1 RS10635
gene id: 351671:XDD1_RS10635
uniprot id: A0A068QVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

351671:XDD1 RS01345
gene id: 351671:XDD1_RS01345
uniprot id: A0A068QQ72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

351671:XDD1 RS07260
gene id: 351671:XDD1_RS07260
uniprot id: A0A068QTX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS16560
gene id: 351671:XDD1_RS16560
uniprot id: A0A068QWG2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Interacts with IscS.
messages: Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.

351671:XDD1 RS17030
gene id: 351671:XDD1_RS17030
uniprot id: A0A068QWH9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

351671:XDD1 RS04930
gene id: 351671:XDD1_RS04930
uniprot id: A0A068QSI7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

351671:XDD1 RS06810
gene id: 351671:XDD1_RS06810
uniprot id: A0A068QQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

351671:XDD1 RS03505
gene id: 351671:XDD1_RS03505
uniprot id: A0A068QNA9
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

351671:XDD1 RS09535
gene id: 351671:XDD1_RS09535
uniprot id: A0A068QSM3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

351671:XDD1 RS10690
gene id: 351671:XDD1_RS10690
uniprot id: A0A068QSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

351671:XDD1 RS14330
gene id: 351671:XDD1_RS14330
uniprot id: A0A068QV17
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

351671:XDD1 RS10375
gene id: 351671:XDD1_RS10375
uniprot id: A0A068QSE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

351671:XDD1 RS07300
gene id: 351671:XDD1_RS07300
uniprot id: A0A068QR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

351671:XDD1 RS11455
gene id: 351671:XDD1_RS11455
uniprot id: A0A068QWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

351671:XDD1 RS16465
gene id: 351671:XDD1_RS16465
uniprot id: A0A068QZM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

351671:XDD1 RS00795
gene id: 351671:XDD1_RS00795
uniprot id: A0A068QPX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

351671:XDD1 RS14430
gene id: 351671:XDD1_RS14430
uniprot id: A0A068QYD0
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

351671:XDD1 RS07655
gene id: 351671:XDD1_RS07655
uniprot id: A0A068QRV3
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS03210
gene id: 351671:XDD1_RS03210
uniprot id: A0A068QN60
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS00520
gene id: 351671:XDD1_RS00520
uniprot id: A0A068QMH0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

351671:XDD1 RS01795
gene id: 351671:XDD1_RS01795
uniprot id: A0A068QQF7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

351671:XDD1 RS04600
gene id: 351671:XDD1_RS04600
uniprot id: A0A068QP07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

351671:XDD1 RS05470
gene id: 351671:XDD1_RS05470
uniprot id: A0A068QPH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS03545
gene id: 351671:XDD1_RS03545
uniprot id: A0A068QRK0
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS14820
gene id: 351671:XDD1_RS14820
uniprot id: A0A068QV97
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

351671:XDD1 RS01775
gene id: 351671:XDD1_RS01775
uniprot id: A0A068QND0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS10300
gene id: 351671:XDD1_RS10300
uniprot id: A0A068QSD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS04210
gene id: 351671:XDD1_RS04210
uniprot id: A0A068QP86
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

351671:XDD1 RS03120
gene id: 351671:XDD1_RS03120
uniprot id: A0A068QN45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

351671:XDD1 RS13745
gene id: 351671:XDD1_RS13745
uniprot id: A0A068QUI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

351671:XDD1 RS13955
gene id: 351671:XDD1_RS13955
uniprot id: A0A068QUS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

351671:XDD1 RS16420
gene id: 351671:XDD1_RS16420
uniprot id: A0A068QZL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

351671:XDD1 RS11625
gene id: 351671:XDD1_RS11625
uniprot id: A0A068QWJ5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS02215
gene id: 351671:XDD1_RS02215
uniprot id: A0A068QMM8
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

351671:XDD1 RS18140
gene id: 351671:XDD1_RS18140
uniprot id: A0A068QX60
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

351671:XDD1 RS06675
gene id: 351671:XDD1_RS06675
uniprot id: A0A068QTF7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

351671:XDD1 RS05940
gene id: 351671:XDD1_RS05940
uniprot id: A0A068QQA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS02710
gene id: 351671:XDD1_RS02710
uniprot id: A0A068QR47
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

351671:XDD1 RS09540
gene id: 351671:XDD1_RS09540
uniprot id: A0A068QVA9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

351671:XDD1 RS10430
gene id: 351671:XDD1_RS10430
uniprot id: A0A068QSH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

351671:XDD1 RS06110
gene id: 351671:XDD1_RS06110
uniprot id: A0A068QQC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Protein-1 exporter (TC 3.A.1.109) family.
messages: Membrane

351671:XDD1 RS07060
gene id: 351671:XDD1_RS07060
uniprot id: A0A068QTU6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

351671:XDD1 RS17080
gene id: 351671:XDD1_RS17080
uniprot id: A0A068QWI6
names: Similarity
messages: Belongs to the group II decarboxylase family.

351671:XDD1 RS09890
gene id: 351671:XDD1_RS09890
uniprot id: A0A068QS89
names: Similarity
messages: Belongs to the peptidase S8 family.

351671:XDD1 RS15420
gene id: 351671:XDD1_RS15420
uniprot id: A0A068QWJ1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS08815
gene id: 351671:XDD1_RS08815
uniprot id: A0A068QSH4
names: Similarity
messages: Belongs to the VgrG protein family.

351671:XDD1 RS02000
gene id: 351671:XDD1_RS02000
uniprot id: A0A068QN35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

351671:XDD1 RS03990
gene id: 351671:XDD1_RS03990
uniprot id: A0A068QNN4
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS16965
gene id: 351671:XDD1_RS16965
uniprot id: A0A068QXI0
names: Similarity
messages: Belongs to the phosphoribulokinase family.

351671:XDD1 RS06735
gene id: 351671:XDD1_RS06735
uniprot id: A0A068QQ28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS03690
gene id: 351671:XDD1_RS03690
uniprot id: A0A068QPC9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

351671:XDD1 RS10755
gene id: 351671:XDD1_RS10755
uniprot id: A0A068QVX7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

351671:XDD1 RS10240
gene id: 351671:XDD1_RS10240
uniprot id: A0A068QSZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

351671:XDD1 RS11180
gene id: 351671:XDD1_RS11180
uniprot id: A0A068QT01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaA family. HdA subfamily.
messages: Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA.
messages: The active form seems to be an ADP-bound monomer. Forms the RIDA complex (regulatory inactivation of DnaA) of ATP-DnaA, ADP-Hda and the DNA-loaded beta sliding clamp (dnaN).

351671:XDD1 RS14025
gene id: 351671:XDD1_RS14025
uniprot id: A0A068QUS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

351671:XDD1 RS12495
gene id: 351671:XDD1_RS12495
uniprot id: A0A068QUE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

351671:XDD1 RS04815
gene id: 351671:XDD1_RS04815
uniprot id: A0A068QP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

351671:XDD1 RS14050
gene id: 351671:XDD1_RS14050
uniprot id: A0A068QUX1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351671:XDD1 RS12205
gene id: 351671:XDD1_RS12205
uniprot id: A0A068QTL2
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

351671:XDD1 RS14755
gene id: 351671:XDD1_RS14755
uniprot id: A0A068QYI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

351671:XDD1 RS13325
gene id: 351671:XDD1_RS13325
uniprot id: A0A068QV94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

351671:XDD1 RS12335
gene id: 351671:XDD1_RS12335
uniprot id: A0A068QUQ4
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

351671:XDD1 RS14440
gene id: 351671:XDD1_RS14440
uniprot id: A0A068QV00
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS16230
gene id: 351671:XDD1_RS16230
uniprot id: A0A068QX30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

351671:XDD1 RS10120
gene id: 351671:XDD1_RS10120
uniprot id: A0A068QSC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

351671:XDD1 RS08895
gene id: 351671:XDD1_RS08895
uniprot id: A0A068QS43
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351671:XDD1 RS17090
gene id: 351671:XDD1_RS17090
uniprot id: A0A068QX76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

351671:XDD1 RS05565
gene id: 351671:XDD1_RS05565
uniprot id: A0A068QQI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

351671:XDD1 RS04005
gene id: 351671:XDD1_RS04005
uniprot id: A0A068QNI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

351671:XDD1 RS19345
gene id: 351671:XDD1_RS19345
uniprot id: A0A068QP82
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the N-terminal section; belongs to the CdiA toxin family.
messages: target cell cytoplasm

351671:XDD1 RS06830
gene id: 351671:XDD1_RS06830
uniprot id: A0A068QQC2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

351671:XDD1 RS15240
gene id: 351671:XDD1_RS15240
uniprot id: A0A068QYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

351671:XDD1 RS16580
gene id: 351671:XDD1_RS16580
uniprot id: A0A068QWB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

351671:XDD1 RS07125
gene id: 351671:XDD1_RS07125
uniprot id: A0A068QTV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

351671:XDD1 RS06360
gene id: 351671:XDD1_RS06360
uniprot id: A0A068QPZ6
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

351671:XDD1 RS13335
gene id: 351671:XDD1_RS13335
uniprot id: A0A068QUB7
names: Similarity
messages: Belongs to the PrpD family.

351671:XDD1 RS12265
gene id: 351671:XDD1_RS12265
uniprot id: A0A068QWY5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS04245
gene id: 351671:XDD1_RS04245
uniprot id: A0A068QP97
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS03695
gene id: 351671:XDD1_RS03695
uniprot id: A0A068QND6
names: Similarity
messages: Belongs to the Smp family.

351671:XDD1 RS16345
gene id: 351671:XDD1_RS16345
uniprot id: A0A068QZL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rnk family.
messages: Interacts with the RNA polymerase.
messages: May act as an anti-Gre factor.

351671:XDD1 RS05695
gene id: 351671:XDD1_RS05695
uniprot id: A0A068QQK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

351671:XDD1 RS10145
gene id: 351671:XDD1_RS10145
uniprot id: A0A068QSA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

351671:XDD1 RS00990
gene id: 351671:XDD1_RS00990
uniprot id: A0A068QMZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351671:XDD1 RS10100
gene id: 351671:XDD1_RS10100
uniprot id: A0A068QSC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

351671:XDD1 RS09385
gene id: 351671:XDD1_RS09385
uniprot id: A0A068QSJ7
names: Similarity
messages: Belongs to the ClpA/ClpB family.

351671:XDD1 RS09105
gene id: 351671:XDD1_RS09105
uniprot id: A0A068QSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351671:XDD1 RS10365
gene id: 351671:XDD1_RS10365
uniprot id: A0A068QVP9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

351671:XDD1 RS05935
gene id: 351671:XDD1_RS05935
uniprot id: A0A068QPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS15670
gene id: 351671:XDD1_RS15670
uniprot id: A0A068QWP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

351671:XDD1 RS08650
gene id: 351671:XDD1_RS08650
uniprot id: A0A068QRF6
names: Function
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
messages: Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.

351671:XDD1 RS03590
gene id: 351671:XDD1_RS03590
uniprot id: A0A068QRK7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12765
gene id: 351671:XDD1_RS12765
uniprot id: A0A068QTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

351671:XDD1 RS01330
gene id: 351671:XDD1_RS01330
uniprot id: A0A068QM95
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

351671:XDD1 RS03905
gene id: 351671:XDD1_RS03905
uniprot id: A0A068QRS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

351671:XDD1 RS01760
gene id: 351671:XDD1_RS01760
uniprot id: A0A068QMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

351671:XDD1 RS03615
gene id: 351671:XDD1_RS03615
uniprot id: A0A068QRL3
names: Similarity
messages: Belongs to the UPF0246 family.

351671:XDD1 RS12190
gene id: 351671:XDD1_RS12190
uniprot id: A0A068QU96
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

351671:XDD1 RS04160
gene id: 351671:XDD1_RS04160
uniprot id: A0A068QNM5
names: Similarity
messages: Belongs to the Hha/YmoA/Cnu family.

351671:XDD1 RS16540
gene id: 351671:XDD1_RS16540
uniprot id: A0A068QWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

351671:XDD1 RS07560
gene id: 351671:XDD1_RS07560
uniprot id: A0A068QQN0
names: Similarity
messages: Belongs to the acylphosphatase family.

351671:XDD1 RS03705
gene id: 351671:XDD1_RS03705
uniprot id: A0A068QNY8
names: Subunit
messages: Monomer.

351671:XDD1 RS00390
gene id: 351671:XDD1_RS00390
uniprot id: A0A068QPQ2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DamX family.
messages: Cell inner membrane
messages: Non-essential cell division protein.
messages: The SPOR domain binds septal peptidoglycans and is required to target DamX to the septal ring.

351671:XDD1 RS14035
gene id: 351671:XDD1_RS14035
uniprot id: A0A068QY67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

351671:XDD1 RS01890
gene id: 351671:XDD1_RS01890
uniprot id: A0A068QML7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06720
gene id: 351671:XDD1_RS06720
uniprot id: A0A068QQS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

351671:XDD1 RS15920
gene id: 351671:XDD1_RS15920
uniprot id: A0A068QZ79
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

351671:XDD1 RS16365
gene id: 351671:XDD1_RS16365
uniprot id: A0A068QWW2
names: Similarity
messages: Belongs to the UPF0307 family.

351671:XDD1 RS11980
gene id: 351671:XDD1_RS11980
uniprot id: A0A068QWT7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS04175
gene id: 351671:XDD1_RS04175
uniprot id: A0A068QPM7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

351671:XDD1 RS14695
gene id: 351671:XDD1_RS14695
uniprot id: A0A068QV74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

351671:XDD1 RS00215
gene id: 351671:XDD1_RS00215
uniprot id: A0A068QM14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

351671:XDD1 RS11930
gene id: 351671:XDD1_RS11930
uniprot id: A0A068QWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351671:XDD1 RS06175
gene id: 351671:XDD1_RS06175
uniprot id: A0A068QQU5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

351671:XDD1 RS01690
gene id: 351671:XDD1_RS01690
uniprot id: A0A068QNB7
names: Function
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.
messages: Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.

351671:XDD1 RS16030
gene id: 351671:XDD1_RS16030
uniprot id: A0A068QW28
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

351671:XDD1 RS08580
gene id: 351671:XDD1_RS08580
uniprot id: A0A068QRW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS07545
gene id: 351671:XDD1_RS07545
uniprot id: A0A068QRD5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

351671:XDD1 RS08935
gene id: 351671:XDD1_RS08935
uniprot id: A0A068QRL5
names: Similarity
names: Subunit
messages: Belongs to the KHG/KDPG aldolase family.
messages: Homotrimer.

351671:XDD1 RS16880
gene id: 351671:XDD1_RS16880
uniprot id: A0A068QX44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

351671:XDD1 RS10435
gene id: 351671:XDD1_RS10435
uniprot id: A0A068QT28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

351671:XDD1 RS04765
gene id: 351671:XDD1_RS04765
uniprot id: A0A068QP29
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

351671:XDD1 RS06295
gene id: 351671:XDD1_RS06295
uniprot id: A0A068QQG5
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

351671:XDD1 RS05995
gene id: 351671:XDD1_RS05995
uniprot id: A0A068QPL3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS01375
gene id: 351671:XDD1_RS01375
uniprot id: A0A068QN65
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

351671:XDD1 RS04835
gene id: 351671:XDD1_RS04835
uniprot id: A0A068QP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

351671:XDD1 RS03460
gene id: 351671:XDD1_RS03460
uniprot id: A0A068QNA1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

351671:XDD1 RS08360
gene id: 351671:XDD1_RS08360
uniprot id: A0A068QRT3
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

351671:XDD1 RS08565
gene id: 351671:XDD1_RS08565
uniprot id: A0A068QUL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.

351671:XDD1 RS07040
gene id: 351671:XDD1_RS07040
uniprot id: A0A068QRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

351671:XDD1 RS11940
gene id: 351671:XDD1_RS11940
uniprot id: A0A068QTG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351671:XDD1 RS11810
gene id: 351671:XDD1_RS11810
uniprot id: A0A068QUH5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RcsD family.
messages: Cell inner membrane
messages: Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
messages: Interacts with RcsC and RcsB.
messages: Phosphorylated by RcsC.

351671:XDD1 RS16865
gene id: 351671:XDD1_RS16865
uniprot id: A0A068QXG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NusG family.
messages: Monomer. Interacts with the transcription termination factor Rho and with RNA polymerase.
messages: Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination.

351671:XDD1 RS08350
gene id: 351671:XDD1_RS08350
uniprot id: A0A068QR30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS04280
gene id: 351671:XDD1_RS04280
uniprot id: A0A068QPQ7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS12885
gene id: 351671:XDD1_RS12885
uniprot id: A0A068QTY0
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU.

351671:XDD1 RS04285
gene id: 351671:XDD1_RS04285
uniprot id: A0A068QNQ1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

351671:XDD1 RS13770
gene id: 351671:XDD1_RS13770
uniprot id: A0A068QUJ3
names: Similarity
messages: Belongs to the UPF0149 family.

351671:XDD1 RS11135
gene id: 351671:XDD1_RS11135
uniprot id: A0A068QTJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

351671:XDD1 RS14740
gene id: 351671:XDD1_RS14740
uniprot id: A0A068QV51
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

351671:XDD1 RS07870
gene id: 351671:XDD1_RS07870
uniprot id: A0A068QRI6
names: Similarity
messages: Belongs to the thioesterase family.

351671:XDD1 RS14580
gene id: 351671:XDD1_RS14580
uniprot id: A0A068QVQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

351671:XDD1 RS12870
gene id: 351671:XDD1_RS12870
uniprot id: A0A068QUL5
names: Similarity
messages: Belongs to the peptidase M17 family.

351671:XDD1 RS16360
gene id: 351671:XDD1_RS16360
uniprot id: A0A068QWC9
names: Similarity
messages: Belongs to the peptidase U62 family.

351671:XDD1 RS11690
gene id: 351671:XDD1_RS11690
uniprot id: A0A068QUF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS16185
gene id: 351671:XDD1_RS16185
uniprot id: A0A068QW18
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

351671:XDD1 RS11640
gene id: 351671:XDD1_RS11640
uniprot id: A0A068QU13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

351671:XDD1 RS13680
gene id: 351671:XDD1_RS13680
uniprot id: A0A068QUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-modifying YgfZ family.
messages: Cytoplasm
messages: Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.

351671:XDD1 RS07035
gene id: 351671:XDD1_RS07035
uniprot id: A0A068QTT0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

351671:XDD1 RS16310
gene id: 351671:XDD1_RS16310
uniprot id: A0A068QW48
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

351671:XDD1 RS10760
gene id: 351671:XDD1_RS10760
uniprot id: A0A068QTQ4
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

351671:XDD1 RS13060
gene id: 351671:XDD1_RS13060
uniprot id: A0A068QU11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

351671:XDD1 RS01650
gene id: 351671:XDD1_RS01650
uniprot id: A0A068QMH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

351671:XDD1 RS15740
gene id: 351671:XDD1_RS15740
uniprot id: A0A068QZ42
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS02010
gene id: 351671:XDD1_RS02010
uniprot id: A0A068QNH0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

351671:XDD1 RS01035
gene id: 351671:XDD1_RS01035
uniprot id: A0A068QMZ9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

351671:XDD1 RS10400
gene id: 351671:XDD1_RS10400
uniprot id: A0A068QSE6
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

351671:XDD1 RS03095
gene id: 351671:XDD1_RS03095
uniprot id: A0A068QN42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

351671:XDD1 RS00200
gene id: 351671:XDD1_RS00200
uniprot id: A0A068QMD5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS14410
gene id: 351671:XDD1_RS14410
uniprot id: A0A068QW10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulation.
messages: Homodimer.

351671:XDD1 RS09720
gene id: 351671:XDD1_RS09720
uniprot id: A0A068QSQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the periplasmic pilus chaperone family.
messages: Periplasm

351671:XDD1 RS07725
gene id: 351671:XDD1_RS07725
uniprot id: A0A068QU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

351671:XDD1 RS11600
gene id: 351671:XDD1_RS11600
uniprot id: A0A068QWH3
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS17875
gene id: 351671:XDD1_RS17875
uniprot id: A0A068QX52
names: Function
names: Similarity
messages: Belongs to the FeoC family.
messages: May function as a transcriptional regulator that controls feoABC expression.

351671:XDD1 RS04390
gene id: 351671:XDD1_RS04390
uniprot id: A0A068QNV7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS05495
gene id: 351671:XDD1_RS05495
uniprot id: A0A068QPH8
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS09740
gene id: 351671:XDD1_RS09740
uniprot id: A0A068QSQ9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

351671:XDD1 RS01065
gene id: 351671:XDD1_RS01065
uniprot id: A0A068QMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS12250
gene id: 351671:XDD1_RS12250
uniprot id: A0A068QTM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

351671:XDD1 RS13695
gene id: 351671:XDD1_RS13695
uniprot id: A0A068QVI9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS03235
gene id: 351671:XDD1_RS03235
uniprot id: A0A068QP42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

351671:XDD1 RS19855
gene id: 351671:XDD1_RS19855
uniprot id: A0A068QPN0
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: host cytosol

351671:XDD1 RS12620
gene id: 351671:XDD1_RS12620
uniprot id: A0A068QX47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS08325
gene id: 351671:XDD1_RS08325
uniprot id: A0A068QR25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

351671:XDD1 RS10180
gene id: 351671:XDD1_RS10180
uniprot id: A0A068QTC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

351671:XDD1 RS16950
gene id: 351671:XDD1_RS16950
uniprot id: A0A068QWL5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS11975
gene id: 351671:XDD1_RS11975
uniprot id: A0A068QU65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351671:XDD1 RS14710
gene id: 351671:XDD1_RS14710
uniprot id: A0A068QW57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

351671:XDD1 RS07155
gene id: 351671:XDD1_RS07155
uniprot id: A0A068QQG7
names: Subcellular Location Annotation
messages: Cytoplasm

351671:XDD1 RS11650
gene id: 351671:XDD1_RS11650
uniprot id: A0A068QUF0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

351671:XDD1 RS15410
gene id: 351671:XDD1_RS15410
uniprot id: A0A068QW59
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

351671:XDD1 RS16740
gene id: 351671:XDD1_RS16740
uniprot id: A0A068QXE4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

351671:XDD1 RS06125
gene id: 351671:XDD1_RS06125
uniprot id: A0A068QQT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTX toxin acyltransferase family.
messages: Cytoplasm
messages: Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.

351671:XDD1 RS01740
gene id: 351671:XDD1_RS01740
uniprot id: A0A068QMJ1
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

351671:XDD1 RS01875
gene id: 351671:XDD1_RS01875
uniprot id: A0A068QN09
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS07890
gene id: 351671:XDD1_RS07890
uniprot id: A0A068QR02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

351671:XDD1 RS05375
gene id: 351671:XDD1_RS05375
uniprot id: A0A068QPB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

351671:XDD1 RS15345
gene id: 351671:XDD1_RS15345
uniprot id: A0A068QVL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Xni family.
messages: Binds 1 K(+) per subunit. The potassium ion strongly increases the affinity for DNA.
messages: Binds 2 Mg(2+) per subunit. Only one magnesium ion has a direct interaction with the protein, the other interactions are indirect.
messages: Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.

351671:XDD1 RS01800
gene id: 351671:XDD1_RS01800
uniprot id: A0A068QND3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

351671:XDD1 RS10955
gene id: 351671:XDD1_RS10955
uniprot id: A0A068QTE8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS06260
gene id: 351671:XDD1_RS06260
uniprot id: A0A068QQW5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

351671:XDD1 RS05870
gene id: 351671:XDD1_RS05870
uniprot id: A0A068QQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

351671:XDD1 RS01450
gene id: 351671:XDD1_RS01450
uniprot id: A0A068QN79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

351671:XDD1 RS15515
gene id: 351671:XDD1_RS15515
uniprot id: A0A068QWL0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

351671:XDD1 RS08180
gene id: 351671:XDD1_RS08180
uniprot id: A0A068QRP6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

351671:XDD1 RS04020
gene id: 351671:XDD1_RS04020
uniprot id: A0A068QRU4
names: Similarity
messages: Belongs to the UPF0234 family.

351671:XDD1 RS15040
gene id: 351671:XDD1_RS15040
uniprot id: A0A068QVE3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

351671:XDD1 RS03065
gene id: 351671:XDD1_RS03065
uniprot id: A0A068QP18
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

351671:XDD1 RS13625
gene id: 351671:XDD1_RS13625
uniprot id: A0A068QUF4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351671:XDD1 RS10640
gene id: 351671:XDD1_RS10640
uniprot id: A0A068QTM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

351671:XDD1 RS17650
gene id: 351671:XDD1_RS17650
uniprot id: A0A068QWZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS11655
gene id: 351671:XDD1_RS11655
uniprot id: A0A068QTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

351671:XDD1 RS01615
gene id: 351671:XDD1_RS01615
uniprot id: A0A068QQC3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS16235
gene id: 351671:XDD1_RS16235
uniprot id: A0A068QW30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS16590
gene id: 351671:XDD1_RS16590
uniprot id: A0A068QX01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

351671:XDD1 RS11660
gene id: 351671:XDD1_RS11660
uniprot id: A0A068QTF0
names: Similarity
messages: Belongs to the elongation factor P family.

351671:XDD1 RS11410
gene id: 351671:XDD1_RS11410
uniprot id: A0A068QU56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

351671:XDD1 RS09630
gene id: 351671:XDD1_RS09630
uniprot id: A0A068QSN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

351671:XDD1 RS02075
gene id: 351671:XDD1_RS02075
uniprot id: A0A068QMK1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

351671:XDD1 RS00905
gene id: 351671:XDD1_RS00905
uniprot id: A0A068QM84
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS01565
gene id: 351671:XDD1_RS01565
uniprot id: A0A068QQB5
names: Similarity
messages: Belongs to the UPF0438 family.

351671:XDD1 RS12000
gene id: 351671:XDD1_RS12000
uniprot id: A0A068QU69
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS13980
gene id: 351671:XDD1_RS13980
uniprot id: A0A068QUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

351671:XDD1 RS01660
gene id: 351671:XDD1_RS01660
uniprot id: A0A068QQD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzzB/Cld/Rol family.
messages: Cell inner membrane
messages: Membrane
messages: Modulates the polysaccharide chain length of enterobacterial common antigen (ECA).
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

351671:XDD1 RS09215
gene id: 351671:XDD1_RS09215
uniprot id: A0A068QSD2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

351671:XDD1 RS05620
gene id: 351671:XDD1_RS05620
uniprot id: A0A068QSV1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

351671:XDD1 RS09180
gene id: 351671:XDD1_RS09180
uniprot id: A0A068QST0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

351671:XDD1 RS11955
gene id: 351671:XDD1_RS11955
uniprot id: A0A068QWT4
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

351671:XDD1 RS13010
gene id: 351671:XDD1_RS13010
uniprot id: A0A068QU01
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

351671:XDD1 RS04060
gene id: 351671:XDD1_RS04060
uniprot id: A0A068QP50
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01455
gene id: 351671:XDD1_RS01455
uniprot id: A0A068QMA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

351671:XDD1 RS16405
gene id: 351671:XDD1_RS16405
uniprot id: A0A068QW89
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

351671:XDD1 RS01655
gene id: 351671:XDD1_RS01655
uniprot id: A0A068QMX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS09525
gene id: 351671:XDD1_RS09525
uniprot id: A0A068QRZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

351671:XDD1 RS10890
gene id: 351671:XDD1_RS10890
uniprot id: A0A068QTT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

351671:XDD1 RS10115
gene id: 351671:XDD1_RS10115
uniprot id: A0A068QTB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

351671:XDD1 RS05490
gene id: 351671:XDD1_RS05490
uniprot id: A0A068QPD1
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

351671:XDD1 RS13395
gene id: 351671:XDD1_RS13395
uniprot id: A0A068QVB2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS06245
gene id: 351671:XDD1_RS06245
uniprot id: A0A068QPX4
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

351671:XDD1 RS02755
gene id: 351671:XDD1_RS02755
uniprot id: A0A068QNJ3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

351671:XDD1 RS17975
gene id: 351671:XDD1_RS17975
uniprot id: A0A068QX74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

351671:XDD1 RS02275
gene id: 351671:XDD1_RS02275
uniprot id: A0A068QMN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

351671:XDD1 RS03935
gene id: 351671:XDD1_RS03935
uniprot id: A0A068QPH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

351671:XDD1 RS10575
gene id: 351671:XDD1_RS10575
uniprot id: A0A068QSI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

351671:XDD1 RS18285
gene id: 351671:XDD1_RS18285
uniprot id: A0A068QXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

351671:XDD1 RS08605
gene id: 351671:XDD1_RS08605
uniprot id: A0A068QRX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

351671:XDD1 RS01350
gene id: 351671:XDD1_RS01350
uniprot id: A0A068QN61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

351671:XDD1 RS00255
gene id: 351671:XDD1_RS00255
uniprot id: A0A068QMQ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

351671:XDD1 RS10950
gene id: 351671:XDD1_RS10950
uniprot id: A0A068QSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.
messages: Membrane

351671:XDD1 RS14905
gene id: 351671:XDD1_RS14905
uniprot id: A0A068QVB6
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05785
gene id: 351671:XDD1_RS05785
uniprot id: A0A068QPL8
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

351671:XDD1 RS15525
gene id: 351671:XDD1_RS15525
uniprot id: A0A068QVQ8
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

351671:XDD1 RS16455
gene id: 351671:XDD1_RS16455
uniprot id: A0A068QWE4
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

351671:XDD1 RS02330
gene id: 351671:XDD1_RS02330
uniprot id: A0A068QNA7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS02245
gene id: 351671:XDD1_RS02245
uniprot id: A0A068QMT5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351671:XDD1 RS10350
gene id: 351671:XDD1_RS10350
uniprot id: A0A068QSD8
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

351671:XDD1 RS16775
gene id: 351671:XDD1_RS16775
uniprot id: A0A068QWI9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351671:XDD1 RS02455
gene id: 351671:XDD1_RS02455
uniprot id: A0A068QN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS15205
gene id: 351671:XDD1_RS15205
uniprot id: A0A068QVH9
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

351671:XDD1 RS09760
gene id: 351671:XDD1_RS09760
uniprot id: A0A068QS66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

351671:XDD1 RS17705
gene id: 351671:XDD1_RS17705
uniprot id: A0A068QX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

351671:XDD1 RS10630
gene id: 351671:XDD1_RS10630
uniprot id: A0A068QT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

351671:XDD1 RS02785
gene id: 351671:XDD1_RS02785
uniprot id: A0A068QR59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

351671:XDD1 RS13585
gene id: 351671:XDD1_RS13585
uniprot id: A0A068QV32
names: Similarity
messages: Belongs to the delta endotoxin family.

351671:XDD1 RS11825
gene id: 351671:XDD1_RS11825
uniprot id: A0A068QTH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

351671:XDD1 RS10390
gene id: 351671:XDD1_RS10390
uniprot id: A0A068QVQ4
names: Similarity
messages: Belongs to the asparaginase 1 family.

351671:XDD1 RS13795
gene id: 351671:XDD1_RS13795
uniprot id: A0A068QV79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LysR transcriptional regulatory family.
messages: Controls the transcription of genes involved in arginine and lysine metabolism.
messages: Homodimer.

351671:XDD1 RS12910
gene id: 351671:XDD1_RS12910
uniprot id: A0A068QTY3
names: Cofactor
names: Function
messages: Binds 1 [2Fe-2S] cluster.
messages: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.

351671:XDD1 RS11855
gene id: 351671:XDD1_RS11855
uniprot id: A0A068QU47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

351671:XDD1 RS11305
gene id: 351671:XDD1_RS11305
uniprot id: A0A068QTP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a tripartite efflux system composed of MdtA, MdtB and MdtC. MdtB forms a heteromultimer with MdtC.

351671:XDD1 RS15100
gene id: 351671:XDD1_RS15100
uniprot id: A0A068QWC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

351671:XDD1 RS11915
gene id: 351671:XDD1_RS11915
uniprot id: A0A068QTF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351671:XDD1 RS09065
gene id: 351671:XDD1_RS09065
uniprot id: A0A068QUW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS06285
gene id: 351671:XDD1_RS06285
uniprot id: A0A068QQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

351671:XDD1 RS11025
gene id: 351671:XDD1_RS11025
uniprot id: A0A068QSU8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

351671:XDD1 RS17960
gene id: 351671:XDD1_RS17960
uniprot id: A0A068R0E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

351671:XDD1 RS09870
gene id: 351671:XDD1_RS09870
uniprot id: A0A068QS86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS08070
gene id: 351671:XDD1_RS08070
uniprot id: A0A068QR32
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS02315
gene id: 351671:XDD1_RS02315
uniprot id: A0A068QNP4
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS02115
gene id: 351671:XDD1_RS02115
uniprot id: A0A068QMK9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

351671:XDD1 RS10665
gene id: 351671:XDD1_RS10665
uniprot id: A0A068QSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

351671:XDD1 RS10230
gene id: 351671:XDD1_RS10230
uniprot id: A0A068QSB8
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

351671:XDD1 RS09950
gene id: 351671:XDD1_RS09950
uniprot id: A0A068QSA2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351671:XDD1 RS01365
gene id: 351671:XDD1_RS01365
uniprot id: A0A068QMT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

351671:XDD1 RS14620
gene id: 351671:XDD1_RS14620
uniprot id: A0A068QV66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

351671:XDD1 RS07045
gene id: 351671:XDD1_RS07045
uniprot id: A0A068QQD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

351671:XDD1 RS16605
gene id: 351671:XDD1_RS16605
uniprot id: A0A068QWB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).
messages: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.

351671:XDD1 RS14525
gene id: 351671:XDD1_RS14525
uniprot id: A0A068QYE8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS12940
gene id: 351671:XDD1_RS12940
uniprot id: A0A068QU14
names: Similarity
messages: Belongs to the P(II) protein family.

351671:XDD1 RS16040
gene id: 351671:XDD1_RS16040
uniprot id: A0A068QZA7
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS11165
gene id: 351671:XDD1_RS11165
uniprot id: A0A068QW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351671:XDD1 RS14460
gene id: 351671:XDD1_RS14460
uniprot id: A0A068QW19
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS00660
gene id: 351671:XDD1_RS00660
uniprot id: A0A068QM13
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS00745
gene id: 351671:XDD1_RS00745
uniprot id: A0A068QMJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

351671:XDD1 RS13845
gene id: 351671:XDD1_RS13845
uniprot id: A0A068QXW9
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

351671:XDD1 RS09515
gene id: 351671:XDD1_RS09515
uniprot id: A0A068QVA5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS01715
gene id: 351671:XDD1_RS01715
uniprot id: A0A068QNC1
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS17025
gene id: 351671:XDD1_RS17025
uniprot id: A0A068QXJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

351671:XDD1 RS07135
gene id: 351671:XDD1_RS07135
uniprot id: A0A068QQG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS00670
gene id: 351671:XDD1_RS00670
uniprot id: A0A068QMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

351671:XDD1 RS09520
gene id: 351671:XDD1_RS09520
uniprot id: A0A068QT30
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

351671:XDD1 RS10770
gene id: 351671:XDD1_RS10770
uniprot id: A0A068QSR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

351671:XDD1 RS14645
gene id: 351671:XDD1_RS14645
uniprot id: A0A068QVR7
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

351671:XDD1 RS06320
gene id: 351671:XDD1_RS06320
uniprot id: A0A068QQH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

351671:XDD1 RS05900
gene id: 351671:XDD1_RS05900
uniprot id: A0A068QQP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

351671:XDD1 RS02195
gene id: 351671:XDD1_RS02195
uniprot id: A0A068QNL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS00315
gene id: 351671:XDD1_RS00315
uniprot id: A0A068QM22
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05690
gene id: 351671:XDD1_RS05690
uniprot id: A0A068QSW4
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

351671:XDD1 RS13440
gene id: 351671:XDD1_RS13440
uniprot id: A0A068QVC3
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

351671:XDD1 RS09590
gene id: 351671:XDD1_RS09590
uniprot id: A0A068QT39
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS13095
gene id: 351671:XDD1_RS13095
uniprot id: A0A068QUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex, which is composed of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

351671:XDD1 RS15770
gene id: 351671:XDD1_RS15770
uniprot id: A0A068QZ48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

351671:XDD1 RS07080
gene id: 351671:XDD1_RS07080
uniprot id: A0A068QTV0
names: Similarity
messages: Belongs to the GST superfamily.

351671:XDD1 RS08635
gene id: 351671:XDD1_RS08635
uniprot id: A0A068QUM6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

351671:XDD1 RS10930
gene id: 351671:XDD1_RS10930
uniprot id: A0A068QTE2
names: Similarity
messages: Belongs to the MotB family.

351671:XDD1 RS03895
gene id: 351671:XDD1_RS03895
uniprot id: A0A068QNL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

351671:XDD1 RS05975
gene id: 351671:XDD1_RS05975
uniprot id: A0A068QPR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS16145
gene id: 351671:XDD1_RS16145
uniprot id: A0A068QW05
names: Similarity
messages: Belongs to the UPF0102 family.

351671:XDD1 RS15355
gene id: 351671:XDD1_RS15355
uniprot id: A0A068QYV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

351671:XDD1 RS05630
gene id: 351671:XDD1_RS05630
uniprot id: A0A068QPF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

351671:XDD1 RS11520
gene id: 351671:XDD1_RS11520
uniprot id: A0A068QTU1
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

351671:XDD1 RS06300
gene id: 351671:XDD1_RS06300
uniprot id: A0A068QT75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

351671:XDD1 RS15255
gene id: 351671:XDD1_RS15255
uniprot id: A0A068QVJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

351671:XDD1 RS07395
gene id: 351671:XDD1_RS07395
uniprot id: A0A068QRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

351671:XDD1 RS00815
gene id: 351671:XDD1_RS00815
uniprot id: A0A068QMK5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

351671:XDD1 RS07085
gene id: 351671:XDD1_RS07085
uniprot id: A0A068QRK9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

351671:XDD1 RS01400
gene id: 351671:XDD1_RS01400
uniprot id: A0A068QN70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

351671:XDD1 RS08575
gene id: 351671:XDD1_RS08575
uniprot id: A0A068QR71
names: Similarity
messages: Belongs to the CFA/CMAS family.

351671:XDD1 RS00810
gene id: 351671:XDD1_RS00810
uniprot id: A0A068QM73
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

351671:XDD1 RS02300
gene id: 351671:XDD1_RS02300
uniprot id: A0A068QMP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

351671:XDD1 RS11615
gene id: 351671:XDD1_RS11615
uniprot id: A0A068QTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351671:XDD1 RS14305
gene id: 351671:XDD1_RS14305
uniprot id: A0A068QV12
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

351671:XDD1 RS07975
gene id: 351671:XDD1_RS07975
uniprot id: A0A068QR16
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS03345
gene id: 351671:XDD1_RS03345
uniprot id: A0A068QNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

351671:XDD1 RS02280
gene id: 351671:XDD1_RS02280
uniprot id: A0A068QMT8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

351671:XDD1 RS16815
gene id: 351671:XDD1_RS16815
uniprot id: A0A068QWE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: Membrane

351671:XDD1 RS13635
gene id: 351671:XDD1_RS13635
uniprot id: A0A068QV43
names: Similarity
messages: Belongs to the HsdR family.

351671:XDD1 RS01805
gene id: 351671:XDD1_RS01805
uniprot id: A0A068QMF3
names: Similarity
messages: Belongs to the VapB family.

351671:XDD1 RS17970
gene id: 351671:XDD1_RS17970
uniprot id: A0A068QX22
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

351671:XDD1 RS00615
gene id: 351671:XDD1_RS00615
uniprot id: A0A068QPU1
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

351671:XDD1 RS06200
gene id: 351671:XDD1_RS06200
uniprot id: A0A068QQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

351671:XDD1 RS04745
gene id: 351671:XDD1_RS04745
uniprot id: A0A068QP26
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351671:XDD1 RS03020
gene id: 351671:XDD1_RS03020
uniprot id: A0A068QN30
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

351671:XDD1 RS12930
gene id: 351671:XDD1_RS12930
uniprot id: A0A068QV04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS06685
gene id: 351671:XDD1_RS06685
uniprot id: A0A068QQ18
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

351671:XDD1 RS03510
gene id: 351671:XDD1_RS03510
uniprot id: A0A068QNF4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

351671:XDD1 RS17740
gene id: 351671:XDD1_RS17740
uniprot id: A0A068QWW4
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS14540
gene id: 351671:XDD1_RS14540
uniprot id: A0A068QYF2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS06240
gene id: 351671:XDD1_RS06240
uniprot id: A0A068QPQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

351671:XDD1 RS05780
gene id: 351671:XDD1_RS05780
uniprot id: A0A068QPH6
names: Similarity
messages: Belongs to the group II decarboxylase family.

351671:XDD1 RS02505
gene id: 351671:XDD1_RS02505
uniprot id: A0A068QNG3
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS05155
gene id: 351671:XDD1_RS05155
uniprot id: A0A068QSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPS (TC 1.B.20) family.
messages: Cell outer membrane
messages: Membrane

351671:XDD1 RS14865
gene id: 351671:XDD1_RS14865
uniprot id: A0A068QYK8
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

351671:XDD1 RS07825
gene id: 351671:XDD1_RS07825
uniprot id: A0A068QRI0
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

351671:XDD1 RS05615
gene id: 351671:XDD1_RS05615
uniprot id: A0A068QQ36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

351671:XDD1 RS17460
gene id: 351671:XDD1_RS17460
uniprot id: A0A068QWV2
names: Similarity
messages: Belongs to the bacterial phospholipase C family.

351671:XDD1 RS15315
gene id: 351671:XDD1_RS15315
uniprot id: A0A068QWG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

351671:XDD1 RS01765
gene id: 351671:XDD1_RS01765
uniprot id: A0A068QMY7
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

351671:XDD1 RS00360
gene id: 351671:XDD1_RS00360
uniprot id: A0A068QM24
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

351671:XDD1 RS01680
gene id: 351671:XDD1_RS01680
uniprot id: A0A068QMX5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

351671:XDD1 RS05355
gene id: 351671:XDD1_RS05355
uniprot id: A0A068QPF8
names: Similarity
messages: Belongs to the GSP E family.

351671:XDD1 RS05660
gene id: 351671:XDD1_RS05660
uniprot id: A0A068QQ44
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

351671:XDD1 RS11170
gene id: 351671:XDD1_RS11170
uniprot id: A0A068QTZ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

351671:XDD1 RS12285
gene id: 351671:XDD1_RS12285
uniprot id: A0A068QUB1
names: Similarity
messages: Belongs to the GST superfamily.

351671:XDD1 RS09495
gene id: 351671:XDD1_RS09495
uniprot id: A0A068QVA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

351671:XDD1 RS16670
gene id: 351671:XDD1_RS16670
uniprot id: A0A068QWC1
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

351671:XDD1 RS03485
gene id: 351671:XDD1_RS03485
uniprot id: A0A068QNF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
messages: Homodimer.

351671:XDD1 RS10095
gene id: 351671:XDD1_RS10095
uniprot id: A0A068QS93
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

351671:XDD1 RS10580
gene id: 351671:XDD1_RS10580
uniprot id: A0A068QSL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

351671:XDD1 RS04025
gene id: 351671:XDD1_RS04025
uniprot id: A0A068QPJ5
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS15190
gene id: 351671:XDD1_RS15190
uniprot id: A0A068QYR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

351671:XDD1 RS05525
gene id: 351671:XDD1_RS05525
uniprot id: A0A068QQ27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Crl family.
messages: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
messages: Cytoplasm

351671:XDD1 RS16850
gene id: 351671:XDD1_RS16850
uniprot id: A0A068QWK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351671:XDD1 RS04185
gene id: 351671:XDD1_RS04185
uniprot id: A0A068QNS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

351671:XDD1 RS11570
gene id: 351671:XDD1_RS11570
uniprot id: A0A068QTV5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

351671:XDD1 RS01020
gene id: 351671:XDD1_RS01020
uniprot id: A0A068QM53
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS14770
gene id: 351671:XDD1_RS14770
uniprot id: A0A068QV87
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

351671:XDD1 RS11765
gene id: 351671:XDD1_RS11765
uniprot id: A0A068QTG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

351671:XDD1 RS13040
gene id: 351671:XDD1_RS13040
uniprot id: A0A068QU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

351671:XDD1 RS01625
gene id: 351671:XDD1_RS01625
uniprot id: A0A068QMC5
names: Similarity
messages: Belongs to the histone deacetylase family.

351671:XDD1 RS12840
gene id: 351671:XDD1_RS12840
uniprot id: A0A068QTZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

351671:XDD1 RS15055
gene id: 351671:XDD1_RS15055
uniprot id: A0A068QWB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

351671:XDD1 RS16715
gene id: 351671:XDD1_RS16715
uniprot id: A0A068QXE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

351671:XDD1 RS01495
gene id: 351671:XDD1_RS01495
uniprot id: A0A068QQA3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

351671:XDD1 RS14395
gene id: 351671:XDD1_RS14395
uniprot id: A0A068QV29
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS15725
gene id: 351671:XDD1_RS15725
uniprot id: A0A068QVR1
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

351671:XDD1 RS03720
gene id: 351671:XDD1_RS03720
uniprot id: A0A068QNE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the exbB/tolQ family.
messages: Cell inner membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

351671:XDD1 RS01590
gene id: 351671:XDD1_RS01590
uniprot id: A0A068QQB9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS05830
gene id: 351671:XDD1_RS05830
uniprot id: A0A068QSY8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

351671:XDD1 RS07290
gene id: 351671:XDD1_RS07290
uniprot id: A0A068QQI7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

351671:XDD1 RS09635
gene id: 351671:XDD1_RS09635
uniprot id: A0A068QVC4
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

351671:XDD1 RS18165
gene id: 351671:XDD1_RS18165
uniprot id: A0A068QX65
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

351671:XDD1 RS00450
gene id: 351671:XDD1_RS00450
uniprot id: A0A068QLZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

351671:XDD1 RS04295
gene id: 351671:XDD1_RS04295
uniprot id: A0A068QPA8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

351671:XDD1 RS06075
gene id: 351671:XDD1_RS06075
uniprot id: A0A068QPM0
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

351671:XDD1 RS15575
gene id: 351671:XDD1_RS15575
uniprot id: A0A068QZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

351671:XDD1 RS12115
gene id: 351671:XDD1_RS12115
uniprot id: A0A068QTM3
names: Similarity
messages: Belongs to the UPF0115 family.

351671:XDD1 RS05485
gene id: 351671:XDD1_RS05485
uniprot id: A0A068QQG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS15650
gene id: 351671:XDD1_RS15650
uniprot id: A0A068QWN7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

351671:XDD1 RS01705
gene id: 351671:XDD1_RS01705
uniprot id: A0A068QMY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WzyE family.
messages: Cell inner membrane
messages: Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
messages: Probably part of a complex composed of WzxE, WzyE and WzzE.

351671:XDD1 RS06270
gene id: 351671:XDD1_RS06270
uniprot id: A0A068QPY0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

351671:XDD1 RS16525
gene id: 351671:XDD1_RS16525
uniprot id: A0A068QZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

351671:XDD1 RS03260
gene id: 351671:XDD1_RS03260
uniprot id: A0A068QN67
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

351671:XDD1 RS13100
gene id: 351671:XDD1_RS13100
uniprot id: A0A068QXE5
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

351671:XDD1 RS00355
gene id: 351671:XDD1_RS00355
uniprot id: A0A068QLY8
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS01335
gene id: 351671:XDD1_RS01335
uniprot id: A0A068QMD4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

351671:XDD1 RS13910
gene id: 351671:XDD1_RS13910
uniprot id: A0A068QVB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecM family.
messages: Periplasm
messages: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation.
messages: cytosol

351671:XDD1 RS08545
gene id: 351671:XDD1_RS08545
uniprot id: A0A068QRD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
messages: Belongs to the Lpp family.
messages: Cell outer membrane
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: cell wall

351671:XDD1 RS16400
gene id: 351671:XDD1_RS16400
uniprot id: A0A068QX93
names: Similarity
messages: Belongs to the peptidase U62 family.

351671:XDD1 RS08640
gene id: 351671:XDD1_RS08640
uniprot id: A0A068QSD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS08075
gene id: 351671:XDD1_RS08075
uniprot id: A0A068QRM4
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS13655
gene id: 351671:XDD1_RS13655
uniprot id: A0A068QUF9
names: Similarity
messages: Belongs to the RecJ family.

351671:XDD1 RS13750
gene id: 351671:XDD1_RS13750
uniprot id: A0A068QUL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

351671:XDD1 RS02430
gene id: 351671:XDD1_RS02430
uniprot id: A0A068QMS4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family. RNase BN subfamily.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities.

351671:XDD1 RS15130
gene id: 351671:XDD1_RS15130
uniprot id: A0A068QVC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

351671:XDD1 RS12270
gene id: 351671:XDD1_RS12270
uniprot id: A0A068QUP4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS07335
gene id: 351671:XDD1_RS07335
uniprot id: A0A068QRQ6
names: Similarity
messages: Belongs to the YkuD family.

351671:XDD1 RS08355
gene id: 351671:XDD1_RS08355
uniprot id: A0A068QR99
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

351671:XDD1 RS05545
gene id: 351671:XDD1_RS05545
uniprot id: A0A068QPD7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351671:XDD1 RS03890
gene id: 351671:XDD1_RS03890
uniprot id: A0A068QNG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS07145
gene id: 351671:XDD1_RS07145
uniprot id: A0A068QTW1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

351671:XDD1 RS14515
gene id: 351671:XDD1_RS14515
uniprot id: A0A068QV13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the P-Pant transferase superfamily. EntD family.
messages: EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.
messages: Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.

351671:XDD1 RS14915
gene id: 351671:XDD1_RS14915
uniprot id: A0A068QYL4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

351671:XDD1 RS14545
gene id: 351671:XDD1_RS14545
uniprot id: A0A068QW33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

351671:XDD1 RS15665
gene id: 351671:XDD1_RS15665
uniprot id: A0A068QWB3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

351671:XDD1 RS05920
gene id: 351671:XDD1_RS05920
uniprot id: A0A068QT04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

351671:XDD1 RS14340
gene id: 351671:XDD1_RS14340
uniprot id: A0A068QYB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

351671:XDD1 RS07190
gene id: 351671:XDD1_RS07190
uniprot id: A0A068QR69
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

351671:XDD1 RS04075
gene id: 351671:XDD1_RS04075
uniprot id: A0A068QNQ0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

351671:XDD1 RS05455
gene id: 351671:XDD1_RS05455
uniprot id: A0A068QSS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

351671:XDD1 RS11005
gene id: 351671:XDD1_RS11005
uniprot id: A0A068QTV3
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

351671:XDD1 RS08695
gene id: 351671:XDD1_RS08695
uniprot id: A0A068QRA2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS10595
gene id: 351671:XDD1_RS10595
uniprot id: A0A068QTL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

351671:XDD1 RS04730
gene id: 351671:XDD1_RS04730
uniprot id: A0A068QPP1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351671:XDD1 RS18325
gene id: 351671:XDD1_RS18325
uniprot id: A0A068QYB2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS14425
gene id: 351671:XDD1_RS14425
uniprot id: A0A068QVM6
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

351671:XDD1 RS07070
gene id: 351671:XDD1_RS07070
uniprot id: A0A068QQE7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

351671:XDD1 RS03180
gene id: 351671:XDD1_RS03180
uniprot id: A0A068QP34
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

351671:XDD1 RS09490
gene id: 351671:XDD1_RS09490
uniprot id: A0A068QS21
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

351671:XDD1 RS09500
gene id: 351671:XDD1_RS09500
uniprot id: A0A068QT25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

351671:XDD1 RS07360
gene id: 351671:XDD1_RS07360
uniprot id: A0A068QRR0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

351671:XDD1 RS11245
gene id: 351671:XDD1_RS11245
uniprot id: A0A068QSZ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

351671:XDD1 RS04595
gene id: 351671:XDD1_RS04595
uniprot id: A0A068QNV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351671:XDD1 RS15225
gene id: 351671:XDD1_RS15225
uniprot id: A0A068QVE0
names: Similarity
messages: Belongs to the skp family.

351671:XDD1 RS14415
gene id: 351671:XDD1_RS14415
uniprot id: A0A068QUZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dGTPase family. Type 1 subfamily.
messages: Homotetramer.
messages: dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.

351671:XDD1 RS13810
gene id: 351671:XDD1_RS13810
uniprot id: A0A068QUN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

351671:XDD1 RS05220
gene id: 351671:XDD1_RS05220
uniprot id: A0A068QPE1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351671:XDD1 RS13990
gene id: 351671:XDD1_RS13990
uniprot id: A0A068QY61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

351671:XDD1 RS00945
gene id: 351671:XDD1_RS00945
uniprot id: A0A068QM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

351671:XDD1 RS02160
gene id: 351671:XDD1_RS02160
uniprot id: A0A068QMR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

351671:XDD1 RS05370
gene id: 351671:XDD1_RS05370
uniprot id: A0A068QQE6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

351671:XDD1 RS05535
gene id: 351671:XDD1_RS05535
uniprot id: A0A068QQH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

351671:XDD1 RS05635
gene id: 351671:XDD1_RS05635
uniprot id: A0A068QPJ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

351671:XDD1 RS11200
gene id: 351671:XDD1_RS11200
uniprot id: A0A068QSY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

351671:XDD1 RS10745
gene id: 351671:XDD1_RS10745
uniprot id: A0A068QSQ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

351671:XDD1 RS11370
gene id: 351671:XDD1_RS11370
uniprot id: A0A068QT59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

351671:XDD1 RS04140
gene id: 351671:XDD1_RS04140
uniprot id: A0A068QNM0
names: Similarity
messages: Belongs to the P(II) protein family.

351671:XDD1 RS12505
gene id: 351671:XDD1_RS12505
uniprot id: A0A068QUS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

351671:XDD1 RS00595
gene id: 351671:XDD1_RS00595
uniprot id: A0A068QMH8
names: Similarity
messages: Belongs to the YicC/YloC family.

351671:XDD1 RS00790
gene id: 351671:XDD1_RS00790
uniprot id: A0A068QMK2
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

351671:XDD1 RS13900
gene id: 351671:XDD1_RS13900
uniprot id: A0A068QUM8
names: Similarity
messages: Belongs to the Nudix hydrolase family.

351671:XDD1 RS02015
gene id: 351671:XDD1_RS02015
uniprot id: A0A068QMI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

351671:XDD1 RS04975
gene id: 351671:XDD1_RS04975
uniprot id: A0A068QP58
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS11100
gene id: 351671:XDD1_RS11100
uniprot id: A0A068QSY6
names: Similarity
messages: Belongs to the ArsC family.

351671:XDD1 RS12925
gene id: 351671:XDD1_RS12925
uniprot id: A0A068QXA6
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS01620
gene id: 351671:XDD1_RS01620
uniprot id: A0A068QNA3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS07330
gene id: 351671:XDD1_RS07330
uniprot id: A0A068QTY7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homotetramer.
messages: Periplasm

351671:XDD1 RS04070
gene id: 351671:XDD1_RS04070
uniprot id: A0A068QPK3
names: Similarity
messages: Belongs to the BolA/IbaG family.

351671:XDD1 RS15690
gene id: 351671:XDD1_RS15690
uniprot id: A0A068QZ30
names: Function
names: Similarity
names: Subunit
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.
messages: Homodimer.

351671:XDD1 RS00930
gene id: 351671:XDD1_RS00930
uniprot id: A0A068QML8
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

351671:XDD1 RS10675
gene id: 351671:XDD1_RS10675
uniprot id: A0A068QT90
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

351671:XDD1 RS16435
gene id: 351671:XDD1_RS16435
uniprot id: A0A068QWE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

351671:XDD1 RS15630
gene id: 351671:XDD1_RS15630
uniprot id: A0A068QVP0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

351671:XDD1 RS00865
gene id: 351671:XDD1_RS00865
uniprot id: A0A068QML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

351671:XDD1 RS15265
gene id: 351671:XDD1_RS15265
uniprot id: A0A068QYT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

351671:XDD1 RS17780
gene id: 351671:XDD1_RS17780
uniprot id: A0A068R0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

351671:XDD1 RS09000
gene id: 351671:XDD1_RS09000
uniprot id: A0A068QRN3
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

351671:XDD1 RS16595
gene id: 351671:XDD1_RS16595
uniprot id: A0A068QZP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

351671:XDD1 RS16800
gene id: 351671:XDD1_RS16800
uniprot id: A0A068QX32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

351671:XDD1 RS14655
gene id: 351671:XDD1_RS14655
uniprot id: A0A068QW53
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS03860
gene id: 351671:XDD1_RS03860
uniprot id: A0A068QRR2
names: Subcellular Location Annotation
messages: Membrane

351671:XDD1 RS18270
gene id: 351671:XDD1_RS18270
uniprot id: A0A068R0M4
names: Cofactor
names: Function
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.

351671:XDD1 RS13105
gene id: 351671:XDD1_RS13105
uniprot id: A0A068QV41
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

351671:XDD1 RS14110
gene id: 351671:XDD1_RS14110
uniprot id: A0A068QVH6
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

351671:XDD1 RS08175
gene id: 351671:XDD1_RS08175
uniprot id: A0A068QR56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

351671:XDD1 RS11595
gene id: 351671:XDD1_RS11595
uniprot id: A0A068QTW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinone-dependent D-lactate dehydrogenase family.
messages: Catalyzes the oxidation of D-lactate to pyruvate.
messages: Cell inner membrane

351671:XDD1 RS16445
gene id: 351671:XDD1_RS16445
uniprot id: A0A068QXA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

351671:XDD1 RS08060
gene id: 351671:XDD1_RS08060
uniprot id: A0A068QS17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism.

351671:XDD1 RS03665
gene id: 351671:XDD1_RS03665
uniprot id: A0A068QPC4
names: Similarity
messages: Belongs to the transglycosylase Slt family.

351671:XDD1 RS12020
gene id: 351671:XDD1_RS12020
uniprot id: A0A068QTK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

351671:XDD1 RS14300
gene id: 351671:XDD1_RS14300
uniprot id: A0A068QUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

351671:XDD1 RS01785
gene id: 351671:XDD1_RS01785
uniprot id: A0A068QMJ9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD, in which XerC interacts with XerD via its C-terminal region, XerD interacts with XerC via its C-terminal region and so on.
messages: FtsK may regulate the catalytic switch between XerC and XerD in the heterotetrameric complex during the two steps of the recombination process.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands.

351671:XDD1 RS13995
gene id: 351671:XDD1_RS13995
uniprot id: A0A068QVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster. Acts by binding directly to DNA. May also regulate the expression of genes outside the dcw cluster.
messages: nucleoid

351671:XDD1 RS14720
gene id: 351671:XDD1_RS14720
uniprot id: A0A068QV77
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

351671:XDD1 RS01060
gene id: 351671:XDD1_RS01060
uniprot id: A0A068QM58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

351671:XDD1 RS03295
gene id: 351671:XDD1_RS03295
uniprot id: A0A068QNC9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

351671:XDD1 RS11440
gene id: 351671:XDD1_RS11440
uniprot id: A0A068QT50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351671:XDD1 RS13820
gene id: 351671:XDD1_RS13820
uniprot id: A0A068QXW2
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

351671:XDD1 RS10070
gene id: 351671:XDD1_RS10070
uniprot id: A0A068QS88
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.

351671:XDD1 RS07265
gene id: 351671:XDD1_RS07265
uniprot id: A0A068QRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

351671:XDD1 RS12525
gene id: 351671:XDD1_RS12525
uniprot id: A0A068QX29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

351671:XDD1 RS03240
gene id: 351671:XDD1_RS03240
uniprot id: A0A068QN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351671:XDD1 RS14345
gene id: 351671:XDD1_RS14345
uniprot id: A0A068QW01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

351671:XDD1 RS01340
gene id: 351671:XDD1_RS01340
uniprot id: A0A068QMS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

351671:XDD1 RS10335
gene id: 351671:XDD1_RS10335
uniprot id: A0A068QT10
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

351671:XDD1 RS08370
gene id: 351671:XDD1_RS08370
uniprot id: A0A068QS90
names: Similarity
messages: Belongs to the barstar family.

351671:XDD1 RS03490
gene id: 351671:XDD1_RS03490
uniprot id: A0A068QNU5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

351671:XDD1 RS16195
gene id: 351671:XDD1_RS16195
uniprot id: A0A068QWN8
names: Similarity
messages: Belongs to the glutamate synthase family.

351671:XDD1 RS16190
gene id: 351671:XDD1_RS16190
uniprot id: A0A068QW65
names: PTM
names: Subcellular Location Annotation
messages: Activation requires a sequential transfer of a phosphate group from a His in the primary transmitter domain, to an Asp in the receiver domain and to a His in the secondary transmitter domain.
messages: Cell inner membrane

351671:XDD1 RS10325
gene id: 351671:XDD1_RS10325
uniprot id: A0A068QSD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

351671:XDD1 RS04355
gene id: 351671:XDD1_RS04355
uniprot id: A0A068QPS7
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

351671:XDD1 RS02320
gene id: 351671:XDD1_RS02320
uniprot id: A0A068QMP7
names: Similarity
messages: Belongs to the intimin/invasin family.

351671:XDD1 RS00855
gene id: 351671:XDD1_RS00855
uniprot id: A0A068QM32
names: Subcellular Location Annotation
messages: Cell inner membrane

351671:XDD1 RS15090
gene id: 351671:XDD1_RS15090
uniprot id: A0A068QVZ7
names: Cofactor
messages: Can also use Mn(2+) ion.