351627:CSAC RS09190
gene id: 351627:CSAC_RS09190
uniprot id: A4XKG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

351627:CSAC RS10845
gene id: 351627:CSAC_RS10845
uniprot id: A4XLE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

351627:CSAC RS11780
gene id: 351627:CSAC_RS11780
uniprot id: A4XLX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

351627:CSAC RS03840
gene id: 351627:CSAC_RS03840
uniprot id: A4XHJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

351627:CSAC RS00150
gene id: 351627:CSAC_RS00150
uniprot id: A4XFK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

351627:CSAC RS12330
gene id: 351627:CSAC_RS12330
uniprot id: A4XM81
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

351627:CSAC RS10790
gene id: 351627:CSAC_RS10790
uniprot id: A4XLD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

351627:CSAC RS06005
gene id: 351627:CSAC_RS06005
uniprot id: A4XIQ9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

351627:CSAC RS07710
gene id: 351627:CSAC_RS07710
uniprot id: A4XJN0
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

351627:CSAC RS10425
gene id: 351627:CSAC_RS10425
uniprot id: A4XL65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

351627:CSAC RS01535
gene id: 351627:CSAC_RS01535
uniprot id: A4XGB2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS06700
gene id: 351627:CSAC_RS06700
uniprot id: A4XJ41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

351627:CSAC RS11485
gene id: 351627:CSAC_RS11485
uniprot id: A4XLR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351627:CSAC RS11265
gene id: 351627:CSAC_RS11265
uniprot id: A4XLM5
names: Similarity
messages: Belongs to the TrpF family.

351627:CSAC RS06860
gene id: 351627:CSAC_RS06860
uniprot id: A4XJ73
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS05385
gene id: 351627:CSAC_RS05385
uniprot id: A4XIE0
names: Similarity
messages: Belongs to the GSP E family.

351627:CSAC RS03460
gene id: 351627:CSAC_RS03460
uniprot id: A4XHB9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS09655
gene id: 351627:CSAC_RS09655
uniprot id: A4XKR1
names: Subcellular Location Annotation
messages: Cytoplasm

351627:CSAC RS06355
gene id: 351627:CSAC_RS06355
uniprot id: A4XIX4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

351627:CSAC RS06375
gene id: 351627:CSAC_RS06375
uniprot id: A4XIX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

351627:CSAC RS08120
gene id: 351627:CSAC_RS08120
uniprot id: A4XJW1
names: Similarity
messages: Belongs to the fabD family.

351627:CSAC RS08510
gene id: 351627:CSAC_RS08510
uniprot id: A4XK35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

351627:CSAC RS01340
gene id: 351627:CSAC_RS01340
uniprot id: A4XG79
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS09805
gene id: 351627:CSAC_RS09805
uniprot id: A4XKU1
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS05005
gene id: 351627:CSAC_RS05005
uniprot id: A4XI66
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

351627:CSAC RS05865
gene id: 351627:CSAC_RS05865
uniprot id: A4XIN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

351627:CSAC RS05540
gene id: 351627:CSAC_RS05540
uniprot id: A4XIH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

351627:CSAC RS13560
gene id: 351627:CSAC_RS13560
uniprot id: A4XMW1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

351627:CSAC RS08160
gene id: 351627:CSAC_RS08160
uniprot id: A4XJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

351627:CSAC RS13240
gene id: 351627:CSAC_RS13240
uniprot id: A4XMQ0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS07100
gene id: 351627:CSAC_RS07100
uniprot id: A4XJC0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351627:CSAC RS03080
gene id: 351627:CSAC_RS03080
uniprot id: A4XH46
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS10795
gene id: 351627:CSAC_RS10795
uniprot id: A4XLD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

351627:CSAC RS07715
gene id: 351627:CSAC_RS07715
uniprot id: A4XJN1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

351627:CSAC RS10840
gene id: 351627:CSAC_RS10840
uniprot id: A4XLE8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

351627:CSAC RS02165
gene id: 351627:CSAC_RS02165
uniprot id: A4XGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Cell membrane

351627:CSAC RS06020
gene id: 351627:CSAC_RS06020
uniprot id: A4XIR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

351627:CSAC RS10185
gene id: 351627:CSAC_RS10185
uniprot id: A4XL17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

351627:CSAC RS11535
gene id: 351627:CSAC_RS11535
uniprot id: A4XLS2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

351627:CSAC RS02625
gene id: 351627:CSAC_RS02625
uniprot id: A4XGX1
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS01715
gene id: 351627:CSAC_RS01715
uniprot id: A4XGE7
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

351627:CSAC RS03715
gene id: 351627:CSAC_RS03715
uniprot id: A4XHH1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

351627:CSAC RS12705
gene id: 351627:CSAC_RS12705
uniprot id: A4XMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS04945
gene id: 351627:CSAC_RS04945
uniprot id: A4XI54
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

351627:CSAC RS12460
gene id: 351627:CSAC_RS12460
uniprot id: A4XMA7
names: Similarity
messages: Belongs to the P(II) protein family.

351627:CSAC RS12425
gene id: 351627:CSAC_RS12425
uniprot id: A4XMA0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

351627:CSAC RS05765
gene id: 351627:CSAC_RS05765
uniprot id: A4XIL5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

351627:CSAC RS12715
gene id: 351627:CSAC_RS12715
uniprot id: A4XMF9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS08345
gene id: 351627:CSAC_RS08345
uniprot id: A4XK04
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

351627:CSAC RS02725
gene id: 351627:CSAC_RS02725
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS07550
gene id: 351627:CSAC_RS07550
uniprot id: A4XJJ9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10525
gene id: 351627:CSAC_RS10525
uniprot id: A4XL85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351627:CSAC RS05035
gene id: 351627:CSAC_RS05035
uniprot id: A4XI72
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

351627:CSAC RS10065
gene id: 351627:CSAC_RS10065
uniprot id: A4XKZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS11605
gene id: 351627:CSAC_RS11605
uniprot id: A4XLT7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS08840
gene id: 351627:CSAC_RS08840
uniprot id: A4XKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351627:CSAC RS14095
gene id: 351627:CSAC_RS14095
uniprot id: A4XN57
names: Similarity
messages: Belongs to the GerABKA family.

351627:CSAC RS05700
gene id: 351627:CSAC_RS05700
uniprot id: A4XIK2
names: Subcellular Location Annotation
messages: Cell membrane

351627:CSAC RS11155
gene id: 351627:CSAC_RS11155
uniprot id: A4XLK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

351627:CSAC RS07755
gene id: 351627:CSAC_RS07755
uniprot id: A4XJN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

351627:CSAC RS10115
gene id: 351627:CSAC_RS10115
uniprot id: A4XL03
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS09445
gene id: 351627:CSAC_RS09445
uniprot id: A4XKL9
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the transpeptidase family.

351627:CSAC RS11400
gene id: 351627:CSAC_RS11400
uniprot id: A4XLP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

351627:CSAC RS11725
gene id: 351627:CSAC_RS11725
uniprot id: A4XLW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

351627:CSAC RS11480
gene id: 351627:CSAC_RS11480
uniprot id: A4XLR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

351627:CSAC RS03955
gene id: 351627:CSAC_RS03955
uniprot id: A4XHL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

351627:CSAC RS02800
gene id: 351627:CSAC_RS02800
uniprot id: A4XGZ8
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS09780
gene id: 351627:CSAC_RS09780
uniprot id: A4XKT6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

351627:CSAC RS01665
gene id: 351627:CSAC_RS01665
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS12395
gene id: 351627:CSAC_RS12395
uniprot id: A4XM94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

351627:CSAC RS08965
gene id: 351627:CSAC_RS08965
uniprot id: A4XKC3
names: Similarity
messages: Belongs to the UPF0297 family.

351627:CSAC RS00725
gene id: 351627:CSAC_RS00725
uniprot id: A4XFW2
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10105
gene id: 351627:CSAC_RS10105
uniprot id: A4XL01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

351627:CSAC RS03415
gene id: 351627:CSAC_RS03415
uniprot id: A4XHB0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS07975
gene id: 351627:CSAC_RS07975
uniprot id: A4XJT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

351627:CSAC RS01475
gene id: 351627:CSAC_RS01475
uniprot id: A4XFX6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS06595
gene id: 351627:CSAC_RS06595
uniprot id: A4XJ20
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS11715
gene id: 351627:CSAC_RS11715
uniprot id: A4XLV9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

351627:CSAC RS01300
gene id: 351627:CSAC_RS01300
uniprot id: A4XG70
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

351627:CSAC RS06310
gene id: 351627:CSAC_RS06310
uniprot id: A4XIW5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

351627:CSAC RS04560
gene id: 351627:CSAC_RS04560
uniprot id: A4XHY2
names: Subcellular Location Annotation
messages: Cytoplasm

351627:CSAC RS02430
gene id: 351627:CSAC_RS02430
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS13610
gene id: 351627:CSAC_RS13610
uniprot id: A4XMX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

351627:CSAC RS11935
gene id: 351627:CSAC_RS11935
uniprot id: A4XM02
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

351627:CSAC RS10825
gene id: 351627:CSAC_RS10825
uniprot id: A4XLE5
names: Similarity
messages: Belongs to the UPF0102 family.

351627:CSAC RS12545
gene id: 351627:CSAC_RS12545
uniprot id: A4XMC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS06335
gene id: 351627:CSAC_RS06335
uniprot id: A4XIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

351627:CSAC RS10345
gene id: 351627:CSAC_RS10345
uniprot id: A4XL49
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

351627:CSAC RS05375
gene id: 351627:CSAC_RS05375
uniprot id: A4XID8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS12565
gene id: 351627:CSAC_RS12565
uniprot id: A4XMC8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351627:CSAC RS02655
gene id: 351627:CSAC_RS02655
uniprot id: A4XGX6
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS01350
gene id: 351627:CSAC_RS01350
uniprot id: A4XG81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

351627:CSAC RS10720
gene id: 351627:CSAC_RS10720
uniprot id: A4XLC4
names: Similarity
messages: Belongs to the asp23 family.

351627:CSAC RS09110
gene id: 351627:CSAC_RS09110
uniprot id: A4XKF2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

351627:CSAC RS06210
gene id: 351627:CSAC_RS06210
uniprot id: A4XIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched-chain polyamine synthase family.
messages: Cytoplasm
messages: Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.

351627:CSAC RS10550
gene id: 351627:CSAC_RS10550
uniprot id: A4XL90
names: Similarity
messages: Belongs to the histone deacetylase family.

351627:CSAC RS02660
gene id: 351627:CSAC_RS02660
uniprot id: A4XGX7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

351627:CSAC RS14060
gene id: 351627:CSAC_RS14060
uniprot id: A4XN50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

351627:CSAC RS11445
gene id: 351627:CSAC_RS11445
uniprot id: A4XLQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

351627:CSAC RS05355
gene id: 351627:CSAC_RS05355
uniprot id: A4XID4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

351627:CSAC RS00315
gene id: 351627:CSAC_RS00315
uniprot id: A4XFN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

351627:CSAC RS09500
gene id: 351627:CSAC_RS09500
uniprot id: A4XKN0
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

351627:CSAC RS02940
gene id: 351627:CSAC_RS02940
uniprot id: A4XH19
names: Similarity
messages: Belongs to the glutamate synthase family.

351627:CSAC RS05990
gene id: 351627:CSAC_RS05990
uniprot id: A4XIQ5
names: Similarity
messages: Belongs to the PGI/PMI family.

351627:CSAC RS08155
gene id: 351627:CSAC_RS08155
uniprot id: A4XJW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

351627:CSAC RS12020
gene id: 351627:CSAC_RS12020
uniprot id: A4XM19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

351627:CSAC RS09890
gene id: 351627:CSAC_RS09890
uniprot id: A4XKV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS08770
gene id: 351627:CSAC_RS08770
uniprot id: A4XK88
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

351627:CSAC RS02585
gene id: 351627:CSAC_RS02585
uniprot id: A4XGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS02490
gene id: 351627:CSAC_RS02490
uniprot id: A4XGU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS04505
gene id: 351627:CSAC_RS04505
uniprot id: A4XHX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

351627:CSAC RS12575
gene id: 351627:CSAC_RS12575
uniprot id: A4XMD0
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351627:CSAC RS09660
gene id: 351627:CSAC_RS09660
uniprot id: A4XKR2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

351627:CSAC RS06315
gene id: 351627:CSAC_RS06315
uniprot id: A4XIW6
names: Similarity
messages: Belongs to the DprA/Smf family.

351627:CSAC RS10385
gene id: 351627:CSAC_RS10385
uniprot id: A4XL57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

351627:CSAC RS09770
gene id: 351627:CSAC_RS09770
uniprot id: A4XKT4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS00360
gene id: 351627:CSAC_RS00360
uniprot id: A4XFP4
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

351627:CSAC RS01365
gene id: 351627:CSAC_RS01365
uniprot id: A4XG84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

351627:CSAC RS04175
gene id: 351627:CSAC_RS04175
uniprot id: A4XHQ9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS03500
gene id: 351627:CSAC_RS03500
uniprot id: A4XHC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS14105
gene id: 351627:CSAC_RS14105
uniprot id: A4XN59
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

351627:CSAC RS09075
gene id: 351627:CSAC_RS09075
uniprot id: A4XKE5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS10260
gene id: 351627:CSAC_RS10260
uniprot id: A4XL32
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS06175
gene id: 351627:CSAC_RS06175
uniprot id: A4XIU2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

351627:CSAC RS11745
gene id: 351627:CSAC_RS11745
uniprot id: A4XLW4
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10085
gene id: 351627:CSAC_RS10085
uniprot id: A4XKZ7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

351627:CSAC RS05780
gene id: 351627:CSAC_RS05780
uniprot id: A4XIL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

351627:CSAC RS03350
gene id: 351627:CSAC_RS03350
uniprot id: A4XH98
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

351627:CSAC RS03430
gene id: 351627:CSAC_RS03430
uniprot id: A4XHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS10055
gene id: 351627:CSAC_RS10055
uniprot id: A4XKZ1
names: Similarity
messages: Belongs to the GARS family.

351627:CSAC RS12770
gene id: 351627:CSAC_RS12770
uniprot id: A4XMG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

351627:CSAC RS11255
gene id: 351627:CSAC_RS11255
uniprot id: A4XLM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

351627:CSAC RS09740
gene id: 351627:CSAC_RS09740
uniprot id: A4XKS8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

351627:CSAC RS00400
gene id: 351627:CSAC_RS00400
uniprot id: A4XFQ1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

351627:CSAC RS05080
gene id: 351627:CSAC_RS05080
uniprot id: A4XI81
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS00320
gene id: 351627:CSAC_RS00320
uniprot id: A4XFN7
names: Similarity
messages: Belongs to the zeta toxin family.

351627:CSAC RS11625
gene id: 351627:CSAC_RS11625
uniprot id: A4XLU1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS06345
gene id: 351627:CSAC_RS06345
uniprot id: A4XIX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

351627:CSAC RS07725
gene id: 351627:CSAC_RS07725
uniprot id: A4XJN3
names: Similarity
messages: Belongs to the MotB family.

351627:CSAC RS13365
gene id: 351627:CSAC_RS13365
uniprot id: A4XMS2
names: Similarity
messages: Belongs to the GSP E family.

351627:CSAC RS09965
gene id: 351627:CSAC_RS09965
uniprot id: A4XKX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

351627:CSAC RS04395
gene id: 351627:CSAC_RS04395
uniprot id: A4XHV1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

351627:CSAC RS12005
gene id: 351627:CSAC_RS12005
uniprot id: A4XM16
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

351627:CSAC RS09825
gene id: 351627:CSAC_RS09825
uniprot id: A4XKU5
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS08995
gene id: 351627:CSAC_RS08995
uniprot id: A4XKC9
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

351627:CSAC RS10215
gene id: 351627:CSAC_RS10215
uniprot id: A4XL23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

351627:CSAC RS08465
gene id: 351627:CSAC_RS08465
uniprot id: A4XK26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

351627:CSAC RS06665
gene id: 351627:CSAC_RS06665
uniprot id: A4XJ34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351627:CSAC RS04550
gene id: 351627:CSAC_RS04550
uniprot id: A4XHY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

351627:CSAC RS15055
gene id: 351627:CSAC_RS15055
uniprot id: A4XIF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

351627:CSAC RS05390
gene id: 351627:CSAC_RS05390
uniprot id: A4XIE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS13625
gene id: 351627:CSAC_RS13625
uniprot id: A4XMX3
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

351627:CSAC RS11315
gene id: 351627:CSAC_RS11315
uniprot id: A4XLN5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351627:CSAC RS02670
gene id: 351627:CSAC_RS02670
uniprot id: A4XGX9
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

351627:CSAC RS01630
gene id: 351627:CSAC_RS01630
uniprot id: A4XM37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

351627:CSAC RS07750
gene id: 351627:CSAC_RS07750
uniprot id: A4XJN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

351627:CSAC RS05060
gene id: 351627:CSAC_RS05060
uniprot id: A4XI77
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

351627:CSAC RS06320
gene id: 351627:CSAC_RS06320
uniprot id: A4XIW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

351627:CSAC RS12940
gene id: 351627:CSAC_RS12940
uniprot id: A4XMJ9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS04520
gene id: 351627:CSAC_RS04520
uniprot id: A4XHX5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

351627:CSAC RS11270
gene id: 351627:CSAC_RS11270
uniprot id: A4XLM6
names: Similarity
messages: Belongs to the TrpC family.

351627:CSAC RS10070
gene id: 351627:CSAC_RS10070
uniprot id: A4XKZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

351627:CSAC RS05770
gene id: 351627:CSAC_RS05770
uniprot id: A4XIL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

351627:CSAC RS07820
gene id: 351627:CSAC_RS07820
uniprot id: A4XJQ2
names: Similarity
messages: Belongs to the HypD family.

351627:CSAC RS10375
gene id: 351627:CSAC_RS10375
uniprot id: A4XL55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

351627:CSAC RS05965
gene id: 351627:CSAC_RS05965
uniprot id: A4XIQ0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351627:CSAC RS07745
gene id: 351627:CSAC_RS07745
uniprot id: A4XJN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

351627:CSAC RS10780
gene id: 351627:CSAC_RS10780
uniprot id: A4XLD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

351627:CSAC RS06825
gene id: 351627:CSAC_RS06825
uniprot id: A4XJ66
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

351627:CSAC RS03330
gene id: 351627:CSAC_RS03330
uniprot id: A4XH94
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10280
gene id: 351627:CSAC_RS10280
uniprot id: A4XL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

351627:CSAC RS09610
gene id: 351627:CSAC_RS09610
uniprot id: A4XKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

351627:CSAC RS06880
gene id: 351627:CSAC_RS06880
uniprot id: A4XJ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

351627:CSAC RS04695
gene id: 351627:CSAC_RS04695
uniprot id: A4XI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

351627:CSAC RS10465
gene id: 351627:CSAC_RS10465
uniprot id: A4XL73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

351627:CSAC RS06380
gene id: 351627:CSAC_RS06380
uniprot id: A4XIX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS01320
gene id: 351627:CSAC_RS01320
uniprot id: A4XG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS10410
gene id: 351627:CSAC_RS10410
uniprot id: A4XL62
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

351627:CSAC RS06955
gene id: 351627:CSAC_RS06955
uniprot id: A4XJ92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS09990
gene id: 351627:CSAC_RS09990
uniprot id: A4XKX8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

351627:CSAC RS04110
gene id: 351627:CSAC_RS04110
uniprot id: A4XHP6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

351627:CSAC RS09300
gene id: 351627:CSAC_RS09300
uniprot id: A4XKJ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

351627:CSAC RS07825
gene id: 351627:CSAC_RS07825
uniprot id: A4XJQ3
names: Similarity
messages: Belongs to the HypE family.

351627:CSAC RS04310
gene id: 351627:CSAC_RS04310
uniprot id: A4XHT5
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

351627:CSAC RS10540
gene id: 351627:CSAC_RS10540
uniprot id: A4XL88
names: Similarity
messages: Belongs to the YicC/YloC family.

351627:CSAC RS11070
gene id: 351627:CSAC_RS11070
uniprot id: A4XLI9
names: Similarity
messages: Belongs to the UPF0047 family.

351627:CSAC RS06690
gene id: 351627:CSAC_RS06690
uniprot id: A4XJ39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

351627:CSAC RS09255
gene id: 351627:CSAC_RS09255
uniprot id: A4XKI1
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

351627:CSAC RS06075
gene id: 351627:CSAC_RS06075
uniprot id: A4XIS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

351627:CSAC RS09745
gene id: 351627:CSAC_RS09745
uniprot id: A4XKS9
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

351627:CSAC RS11920
gene id: 351627:CSAC_RS11920
uniprot id: A4XLZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

351627:CSAC RS02900
gene id: 351627:CSAC_RS02900
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS00290
gene id: 351627:CSAC_RS00290
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS01975
gene id: 351627:CSAC_RS01975
uniprot id: A4XGJ7
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10880
gene id: 351627:CSAC_RS10880
uniprot id: A4XLF6
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

351627:CSAC RS09160
gene id: 351627:CSAC_RS09160
uniprot id: A4XKG2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

351627:CSAC RS10695
gene id: 351627:CSAC_RS10695
uniprot id: A4XLB9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

351627:CSAC RS11110
gene id: 351627:CSAC_RS11110
uniprot id: A4XLJ6
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS00785
gene id: 351627:CSAC_RS00785
uniprot id: A4XFX5
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10520
gene id: 351627:CSAC_RS10520
uniprot id: A4XL84
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS02270
gene id: 351627:CSAC_RS02270
uniprot id: A4XGQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351627:CSAC RS12570
gene id: 351627:CSAC_RS12570
uniprot id: A4XMC9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS08295
gene id: 351627:CSAC_RS08295
uniprot id: A4XJZ4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351627:CSAC RS10860
gene id: 351627:CSAC_RS10860
uniprot id: A4XLF2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

351627:CSAC RS06270
gene id: 351627:CSAC_RS06270
uniprot id: A4XIV7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

351627:CSAC RS10245
gene id: 351627:CSAC_RS10245
uniprot id: A4XL29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

351627:CSAC RS10330
gene id: 351627:CSAC_RS10330
uniprot id: A4XL46
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

351627:CSAC RS08430
gene id: 351627:CSAC_RS08430
uniprot id: A4XK20
names: Similarity
messages: Belongs to the bacterial flagellin family.

351627:CSAC RS11720
gene id: 351627:CSAC_RS11720
uniprot id: A4XLW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

351627:CSAC RS06040
gene id: 351627:CSAC_RS06040
uniprot id: A4XIR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS10620
gene id: 351627:CSAC_RS10620
uniprot id: A4XLA5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

351627:CSAC RS04655
gene id: 351627:CSAC_RS04655
uniprot id: A4XHZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

351627:CSAC RS01305
gene id: 351627:CSAC_RS01305
uniprot id: A4XG71
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

351627:CSAC RS07695
gene id: 351627:CSAC_RS07695
uniprot id: A4XJM7
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

351627:CSAC RS00015
gene id: 351627:CSAC_RS00015
uniprot id: A4XFI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

351627:CSAC RS06830
gene id: 351627:CSAC_RS06830
uniprot id: A4XJ67
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS08795
gene id: 351627:CSAC_RS08795
uniprot id: A4XK93
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

351627:CSAC RS08365
gene id: 351627:CSAC_RS08365
uniprot id: A4XK08
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

351627:CSAC RS13645
gene id: 351627:CSAC_RS13645
uniprot id: A4XMX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS00250
gene id: 351627:CSAC_RS00250
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS03605
gene id: 351627:CSAC_RS03605
uniprot id: A4XHE9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS05815
gene id: 351627:CSAC_RS05815
uniprot id: A4XIM3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

351627:CSAC RS11515
gene id: 351627:CSAC_RS11515
uniprot id: A4XLR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

351627:CSAC RS04255
gene id: 351627:CSAC_RS04255
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS03950
gene id: 351627:CSAC_RS03950
uniprot id: A4XHL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

351627:CSAC RS01765
gene id: 351627:CSAC_RS01765
uniprot id: A4XGF7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351627:CSAC RS10370
gene id: 351627:CSAC_RS10370
uniprot id: A4XL54
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

351627:CSAC RS06365
gene id: 351627:CSAC_RS06365
uniprot id: A4XIX6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

351627:CSAC RS05125
gene id: 351627:CSAC_RS05125
uniprot id: A4XI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS12040
gene id: 351627:CSAC_RS12040
uniprot id: A4XM23
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

351627:CSAC RS06535
gene id: 351627:CSAC_RS06535
uniprot id: A4XJ08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

351627:CSAC RS10295
gene id: 351627:CSAC_RS10295
uniprot id: A4XL39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.

351627:CSAC RS08855
gene id: 351627:CSAC_RS08855
uniprot id: A4XKA4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

351627:CSAC RS10700
gene id: 351627:CSAC_RS10700
uniprot id: A4XLC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

351627:CSAC RS09845
gene id: 351627:CSAC_RS09845
uniprot id: A4XKU9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

351627:CSAC RS03020
gene id: 351627:CSAC_RS03020
uniprot id: A4XH35
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

351627:CSAC RS04950
gene id: 351627:CSAC_RS04950
uniprot id: A4XI55
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

351627:CSAC RS06790
gene id: 351627:CSAC_RS06790
uniprot id: A4XJ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

351627:CSAC RS12035
gene id: 351627:CSAC_RS12035
uniprot id: A4XM22
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

351627:CSAC RS11570
gene id: 351627:CSAC_RS11570
uniprot id: A4XLS9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

351627:CSAC RS13495
gene id: 351627:CSAC_RS13495
uniprot id: A4XMU7
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351627:CSAC RS05985
gene id: 351627:CSAC_RS05985
uniprot id: A4XIQ4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

351627:CSAC RS02475
gene id: 351627:CSAC_RS02475
uniprot id: A4XGU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

351627:CSAC RS06025
gene id: 351627:CSAC_RS06025
uniprot id: A4XIR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

351627:CSAC RS08020
gene id: 351627:CSAC_RS08020
uniprot id: A4XJU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS13830
gene id: 351627:CSAC_RS13830
uniprot id: A4XN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS02075
gene id: 351627:CSAC_RS02075
uniprot id: A4XGL7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

351627:CSAC RS03935
gene id: 351627:CSAC_RS03935
uniprot id: A4XHL4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

351627:CSAC RS11910
gene id: 351627:CSAC_RS11910
uniprot id: A4XLZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

351627:CSAC RS01710
gene id: 351627:CSAC_RS01710
uniprot id: A4XGE6
names: Similarity
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.

351627:CSAC RS07655
gene id: 351627:CSAC_RS07655
uniprot id: A4XJL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS05260
gene id: 351627:CSAC_RS05260
uniprot id: A4XIB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

351627:CSAC RS01070
gene id: 351627:CSAC_RS01070
uniprot id: A4XG24
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

351627:CSAC RS14165
gene id: 351627:CSAC_RS14165
uniprot id: A4XH52
names: Similarity
messages: Belongs to the SecB family.

351627:CSAC RS01625
gene id: 351627:CSAC_RS01625
uniprot id: A4XGD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

351627:CSAC RS11440
gene id: 351627:CSAC_RS11440
uniprot id: A4XLQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

351627:CSAC RS09600
gene id: 351627:CSAC_RS09600
uniprot id: A4XKQ0
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS09960
gene id: 351627:CSAC_RS09960
uniprot id: A4XKX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

351627:CSAC RS04960
gene id: 351627:CSAC_RS04960
uniprot id: A4XI57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

351627:CSAC RS05845
gene id: 351627:CSAC_RS05845
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS03720
gene id: 351627:CSAC_RS03720
uniprot id: A4XHH2
names: Similarity
messages: Belongs to the class-I fumarase family.

351627:CSAC RS01095
gene id: 351627:CSAC_RS01095
uniprot id: A4XG29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

351627:CSAC RS11805
gene id: 351627:CSAC_RS11805
uniprot id: A4XLX6
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

351627:CSAC RS11430
gene id: 351627:CSAC_RS11430
uniprot id: A4XLQ1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

351627:CSAC RS14010
gene id: 351627:CSAC_RS14010
uniprot id: A4XN40
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04875
gene id: 351627:CSAC_RS04875
uniprot id: A4XI40
names: Similarity
messages: Belongs to the IMPACT family.

351627:CSAC RS11415
gene id: 351627:CSAC_RS11415
uniprot id: A4XLQ0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

351627:CSAC RS13450
gene id: 351627:CSAC_RS13450
uniprot id: A4XMT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

351627:CSAC RS11915
gene id: 351627:CSAC_RS11915
uniprot id: A4XLZ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

351627:CSAC RS12520
gene id: 351627:CSAC_RS12520
uniprot id: A4XMB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS14075
gene id: 351627:CSAC_RS14075
uniprot id: A4XN53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

351627:CSAC RS09045
gene id: 351627:CSAC_RS09045
uniprot id: A4XKD9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

351627:CSAC RS01650
gene id: 351627:CSAC_RS01650
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS09080
gene id: 351627:CSAC_RS09080
uniprot id: A4XKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

351627:CSAC RS04050
gene id: 351627:CSAC_RS04050
uniprot id: A4XHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

351627:CSAC RS06800
gene id: 351627:CSAC_RS06800
uniprot id: A4XJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS04405
gene id: 351627:CSAC_RS04405
uniprot id: A4XHV3
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

351627:CSAC RS07500
gene id: 351627:CSAC_RS07500
uniprot id: A4XJJ3
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS11610
gene id: 351627:CSAC_RS11610
uniprot id: A4XLT8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351627:CSAC RS06745
gene id: 351627:CSAC_RS06745
uniprot id: A4XJ50
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS14030
gene id: 351627:CSAC_RS14030
uniprot id: A4XN44
names: Similarity
messages: Belongs to the ParB family.

351627:CSAC RS01985
gene id: 351627:CSAC_RS01985
uniprot id: A4XGJ9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

351627:CSAC RS02410
gene id: 351627:CSAC_RS02410
uniprot id: A4XGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

351627:CSAC RS04265
gene id: 351627:CSAC_RS04265
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS09095
gene id: 351627:CSAC_RS09095
uniprot id: A4XKE9
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

351627:CSAC RS12470
gene id: 351627:CSAC_RS12470
uniprot id: A4XMA9
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

351627:CSAC RS12885
gene id: 351627:CSAC_RS12885
uniprot id: A4XMI8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS07920
gene id: 351627:CSAC_RS07920
uniprot id: A4XJS2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

351627:CSAC RS08790
gene id: 351627:CSAC_RS08790
uniprot id: A4XK92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

351627:CSAC RS02090
gene id: 351627:CSAC_RS02090
uniprot id: A4XGM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS00935
gene id: 351627:CSAC_RS00935
uniprot id: A4XFZ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS04005
gene id: 351627:CSAC_RS04005
uniprot id: A4XHM8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

351627:CSAC RS09920
gene id: 351627:CSAC_RS09920
uniprot id: A4XKW4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

351627:CSAC RS11930
gene id: 351627:CSAC_RS11930
uniprot id: A4XM01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

351627:CSAC RS11810
gene id: 351627:CSAC_RS11810
uniprot id: A4XLX7
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

351627:CSAC RS02300
gene id: 351627:CSAC_RS02300
uniprot id: A4XGQ9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351627:CSAC RS02280
gene id: 351627:CSAC_RS02280
uniprot id: A4XGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS10200
gene id: 351627:CSAC_RS10200
uniprot id: A4XL20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

351627:CSAC RS08955
gene id: 351627:CSAC_RS08955
uniprot id: A4XKC1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

351627:CSAC RS01430
gene id: 351627:CSAC_RS01430
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS11905
gene id: 351627:CSAC_RS11905
uniprot id: A4XLZ6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS12320
gene id: 351627:CSAC_RS12320
uniprot id: A4XM79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

351627:CSAC RS08755
gene id: 351627:CSAC_RS08755
uniprot id: A4XK85
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

351627:CSAC RS11250
gene id: 351627:CSAC_RS11250
uniprot id: A4XLM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

351627:CSAC RS09580
gene id: 351627:CSAC_RS09580
uniprot id: A4XKP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

351627:CSAC RS13665
gene id: 351627:CSAC_RS13665
uniprot id: A4XMY1
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

351627:CSAC RS12155
gene id: 351627:CSAC_RS12155
uniprot id: A4XM46
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

351627:CSAC RS03480
gene id: 351627:CSAC_RS03480
uniprot id: A4XHC3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

351627:CSAC RS01925
gene id: 351627:CSAC_RS01925
uniprot id: A4XGI9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS11960
gene id: 351627:CSAC_RS11960
uniprot id: A4XM07
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS11560
gene id: 351627:CSAC_RS11560
uniprot id: A4XLS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

351627:CSAC RS10415
gene id: 351627:CSAC_RS10415
uniprot id: A4XL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

351627:CSAC RS03150
gene id: 351627:CSAC_RS03150
uniprot id: A4XH60
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

351627:CSAC RS12825
gene id: 351627:CSAC_RS12825
uniprot id: A4XMH6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

351627:CSAC RS00010
gene id: 351627:CSAC_RS00010
uniprot id: A4XFI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

351627:CSAC RS04710
gene id: 351627:CSAC_RS04710
uniprot id: A4XI07
names: Similarity
messages: Belongs to the UPF0749 family.

351627:CSAC RS09085
gene id: 351627:CSAC_RS09085
uniprot id: A4XKE7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

351627:CSAC RS08335
gene id: 351627:CSAC_RS08335
uniprot id: A4XK02
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

351627:CSAC RS06785
gene id: 351627:CSAC_RS06785
uniprot id: A4XJ58
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

351627:CSAC RS13595
gene id: 351627:CSAC_RS13595
uniprot id: A4XMW9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS08835
gene id: 351627:CSAC_RS08835
uniprot id: A4XKA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

351627:CSAC RS08985
gene id: 351627:CSAC_RS08985
uniprot id: A4XKC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

351627:CSAC RS10775
gene id: 351627:CSAC_RS10775
uniprot id: A4XLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

351627:CSAC RS08265
gene id: 351627:CSAC_RS08265
uniprot id: A4XJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS03970
gene id: 351627:CSAC_RS03970
uniprot id: A4XHM1
names: Similarity
messages: Belongs to the UPF0758 family.

351627:CSAC RS07310
gene id: 351627:CSAC_RS07310
uniprot id: A4XJF9
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS06430
gene id: 351627:CSAC_RS06430
uniprot id: A4XIY9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS13985
gene id: 351627:CSAC_RS13985
uniprot id: A4XN35
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351627:CSAC RS12280
gene id: 351627:CSAC_RS12280
uniprot id: A4XM71
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

351627:CSAC RS13745
gene id: 351627:CSAC_RS13745
uniprot id: A4XMZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

351627:CSAC RS13545
gene id: 351627:CSAC_RS13545
uniprot id: A4XMV7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS02550
gene id: 351627:CSAC_RS02550
uniprot id: A4XGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS00745
gene id: 351627:CSAC_RS00745
uniprot id: A4XFW6
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS13050
gene id: 351627:CSAC_RS13050
uniprot id: A4XML6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

351627:CSAC RS06325
gene id: 351627:CSAC_RS06325
uniprot id: A4XIW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

351627:CSAC RS06655
gene id: 351627:CSAC_RS06655
uniprot id: A4XJ32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS01835
gene id: 351627:CSAC_RS01835
uniprot id: A4XGH1
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS09775
gene id: 351627:CSAC_RS09775
uniprot id: A4XKT5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

351627:CSAC RS02240
gene id: 351627:CSAC_RS02240
uniprot id: A4XGP7
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

351627:CSAC RS09235
gene id: 351627:CSAC_RS09235
uniprot id: A4XKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

351627:CSAC RS10430
gene id: 351627:CSAC_RS10430
uniprot id: A4XL66
names: Similarity
messages: Belongs to the ribF family.

351627:CSAC RS06740
gene id: 351627:CSAC_RS06740
uniprot id: A4XJ49
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

351627:CSAC RS09715
gene id: 351627:CSAC_RS09715
uniprot id: A4XKS3
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

351627:CSAC RS12650
gene id: 351627:CSAC_RS12650
uniprot id: A4XME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane.

351627:CSAC RS02225
gene id: 351627:CSAC_RS02225
uniprot id: A4XGP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05995
gene id: 351627:CSAC_RS05995
uniprot id: A4XIQ6
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

351627:CSAC RS11330
gene id: 351627:CSAC_RS11330
uniprot id: A4XLN8
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10035
gene id: 351627:CSAC_RS10035
uniprot id: A4XKY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

351627:CSAC RS00500
gene id: 351627:CSAC_RS00500
uniprot id: A4XFR9
names: Similarity
messages: Belongs to the RutC family.

351627:CSAC RS11555
gene id: 351627:CSAC_RS11555
uniprot id: A4XLS6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

351627:CSAC RS13120
gene id: 351627:CSAC_RS13120
uniprot id: A4XMM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

351627:CSAC RS11135
gene id: 351627:CSAC_RS11135
uniprot id: A4XLK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

351627:CSAC RS08205
gene id: 351627:CSAC_RS08205
uniprot id: A4XJX6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

351627:CSAC RS13435
gene id: 351627:CSAC_RS13435
uniprot id: A4XMT6
names: Similarity
messages: Belongs to the RNase H family.

351627:CSAC RS08660
gene id: 351627:CSAC_RS08660
uniprot id: A4XK65
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

351627:CSAC RS05830
gene id: 351627:CSAC_RS05830
uniprot id: A4XIM4
names: Similarity
messages: Belongs to the xylose isomerase family.

351627:CSAC RS07395
gene id: 351627:CSAC_RS07395
uniprot id: A4XJH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11455
gene id: 351627:CSAC_RS11455
uniprot id: A4XLQ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

351627:CSAC RS06805
gene id: 351627:CSAC_RS06805
uniprot id: A4XJ62
names: Similarity
messages: Belongs to the P(II) protein family.

351627:CSAC RS12695
gene id: 351627:CSAC_RS12695
uniprot id: A4XMF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 30 family.

351627:CSAC RS04360
gene id: 351627:CSAC_RS04360
uniprot id: A4XHU4
names: Similarity
messages: Belongs to the UPF0342 family.

351627:CSAC RS00795
gene id: 351627:CSAC_RS00795
uniprot id: A4XFX6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS06415
gene id: 351627:CSAC_RS06415
uniprot id: A4XIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

351627:CSAC RS11875
gene id: 351627:CSAC_RS11875
uniprot id: A4XLZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

351627:CSAC RS09470
gene id: 351627:CSAC_RS09470
uniprot id: A4XKM4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

351627:CSAC RS12645
gene id: 351627:CSAC_RS12645
uniprot id: A4XME5
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10120
gene id: 351627:CSAC_RS10120
uniprot id: A4XL04
names: Similarity
messages: Belongs to the HypE family.

351627:CSAC RS10305
gene id: 351627:CSAC_RS10305
uniprot id: A4XL41
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

351627:CSAC RS11965
gene id: 351627:CSAC_RS11965
uniprot id: A4XM08
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

351627:CSAC RS12275
gene id: 351627:CSAC_RS12275
uniprot id: A4XM70
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

351627:CSAC RS05055
gene id: 351627:CSAC_RS05055
uniprot id: A4XI76
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

351627:CSAC RS05170
gene id: 351627:CSAC_RS05170
uniprot id: A4XI97
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

351627:CSAC RS03435
gene id: 351627:CSAC_RS03435
uniprot id: A4XHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11140
gene id: 351627:CSAC_RS11140
uniprot id: A4XLK2
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351627:CSAC RS03515
gene id: 351627:CSAC_RS03515
uniprot id: A4XHD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

351627:CSAC RS02705
gene id: 351627:CSAC_RS02705
uniprot id: A4XGY6
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

351627:CSAC RS10380
gene id: 351627:CSAC_RS10380
uniprot id: A4XL56
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

351627:CSAC RS13735
gene id: 351627:CSAC_RS13735
uniprot id: A4XMZ2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

351627:CSAC RS06090
gene id: 351627:CSAC_RS06090
uniprot id: A4XIS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

351627:CSAC RS00925
gene id: 351627:CSAC_RS00925
uniprot id: A4XFZ6
names: Similarity
messages: Belongs to the ComB family.

351627:CSAC RS04315
gene id: 351627:CSAC_RS04315
uniprot id: A4XHT6
names: Similarity
messages: Belongs to the UPF0047 family.

351627:CSAC RS06900
gene id: 351627:CSAC_RS06900
uniprot id: A4XJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

351627:CSAC RS01265
gene id: 351627:CSAC_RS01265
uniprot id: A4XG63
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

351627:CSAC RS11235
gene id: 351627:CSAC_RS11235
uniprot id: A4XLL9
names: Similarity
messages: Belongs to the asparagine synthetase family.

351627:CSAC RS02155
gene id: 351627:CSAC_RS02155
uniprot id: A4XGN3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

351627:CSAC RS06360
gene id: 351627:CSAC_RS06360
uniprot id: A4XIX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

351627:CSAC RS07770
gene id: 351627:CSAC_RS07770
uniprot id: A4XJP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

351627:CSAC RS06000
gene id: 351627:CSAC_RS06000
uniprot id: A4XIQ7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

351627:CSAC RS09645
gene id: 351627:CSAC_RS09645
uniprot id: A4XKQ9
names: Similarity
messages: Belongs to the YggT family.

351627:CSAC RS05785
gene id: 351627:CSAC_RS05785
uniprot id: A4XIL9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

351627:CSAC RS00540
gene id: 351627:CSAC_RS00540
uniprot id: A4XFS7
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

351627:CSAC RS13015
gene id: 351627:CSAC_RS13015
uniprot id: A4XML1
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10665
gene id: 351627:CSAC_RS10665
uniprot id: A4XLB4
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

351627:CSAC RS03990
gene id: 351627:CSAC_RS03990
uniprot id: A4XHM5
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

351627:CSAC RS06735
gene id: 351627:CSAC_RS06735
uniprot id: A4XJ48
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

351627:CSAC RS09615
gene id: 351627:CSAC_RS09615
uniprot id: A4XKQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

351627:CSAC RS07390
gene id: 351627:CSAC_RS07390
uniprot id: A4XJH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

351627:CSAC RS01705
gene id: 351627:CSAC_RS01705
uniprot id: A4XGE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

351627:CSAC RS11575
gene id: 351627:CSAC_RS11575
uniprot id: A4XLT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

351627:CSAC RS05070
gene id: 351627:CSAC_RS05070
uniprot id: A4XI79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS11510
gene id: 351627:CSAC_RS11510
uniprot id: A4XLR7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

351627:CSAC RS10865
gene id: 351627:CSAC_RS10865
uniprot id: A4XLF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

351627:CSAC RS10355
gene id: 351627:CSAC_RS10355
uniprot id: A4XL51
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

351627:CSAC RS09815
gene id: 351627:CSAC_RS09815
uniprot id: A4XKU3
names: Similarity
messages: Belongs to the leucine-binding protein family.

351627:CSAC RS11630
gene id: 351627:CSAC_RS11630
uniprot id: A4XLU2
names: Similarity
messages: Belongs to the peptidase M18 family.

351627:CSAC RS08245
gene id: 351627:CSAC_RS08245
uniprot id: A4XJY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS05100
gene id: 351627:CSAC_RS05100
uniprot id: A4XI85
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

351627:CSAC RS07635
gene id: 351627:CSAC_RS07635
uniprot id: A4XJL5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

351627:CSAC RS04995
gene id: 351627:CSAC_RS04995
uniprot id: A4XI64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

351627:CSAC RS10335
gene id: 351627:CSAC_RS10335
uniprot id: A4XL47
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

351627:CSAC RS07890
gene id: 351627:CSAC_RS07890
uniprot id: A4XJR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS10490
gene id: 351627:CSAC_RS10490
uniprot id: A4XL78
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

351627:CSAC RS08685
gene id: 351627:CSAC_RS08685
uniprot id: A4XK71
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

351627:CSAC RS03535
gene id: 351627:CSAC_RS03535
uniprot id: A4XHD4
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS00605
gene id: 351627:CSAC_RS00605
uniprot id: A4XFU0
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS06760
gene id: 351627:CSAC_RS06760
uniprot id: A4XJ53
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

351627:CSAC RS04565
gene id: 351627:CSAC_RS04565
uniprot id: A4XHY3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

351627:CSAC RS02535
gene id: 351627:CSAC_RS02535
uniprot id: A4XGV5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS07660
gene id: 351627:CSAC_RS07660
uniprot id: A4XJM0
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

351627:CSAC RS04860
gene id: 351627:CSAC_RS04860
uniprot id: A4XI37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

351627:CSAC RS10810
gene id: 351627:CSAC_RS10810
uniprot id: A4XLE2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

351627:CSAC RS12220
gene id: 351627:CSAC_RS12220
uniprot id: A4XM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS12250
gene id: 351627:CSAC_RS12250
uniprot id: A4XM65
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS01865
gene id: 351627:CSAC_RS01865
uniprot id: A4XGH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

351627:CSAC RS01615
gene id: 351627:CSAC_RS01615
uniprot id: A4XGC8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

351627:CSAC RS08830
gene id: 351627:CSAC_RS08830
uniprot id: A4XK99
names: Similarity
messages: Belongs to the CapA family.

351627:CSAC RS08010
gene id: 351627:CSAC_RS08010
uniprot id: A4XJT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

351627:CSAC RS07455
gene id: 351627:CSAC_RS07455
uniprot id: A4XJI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

351627:CSAC RS07255
gene id: 351627:CSAC_RS07255
uniprot id: A4XJE6
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS06705
gene id: 351627:CSAC_RS06705
uniprot id: A4XJ42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

351627:CSAC RS13160
gene id: 351627:CSAC_RS13160
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS12420
gene id: 351627:CSAC_RS12420
uniprot id: A4XM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

351627:CSAC RS12240
gene id: 351627:CSAC_RS12240
uniprot id: A4XM63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

351627:CSAC RS00285
gene id: 351627:CSAC_RS00285
uniprot id: A4XFN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

351627:CSAC RS07790
gene id: 351627:CSAC_RS07790
uniprot id: A4XJP6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Belongs to the complex I 49 kDa subunit family.

351627:CSAC RS10090
gene id: 351627:CSAC_RS10090
uniprot id: A4XKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

351627:CSAC RS11145
gene id: 351627:CSAC_RS11145
uniprot id: A4XLK3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

351627:CSAC RS01565
gene id: 351627:CSAC_RS01565
uniprot id: A4XGB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS09450
gene id: 351627:CSAC_RS09450
uniprot id: A4XKM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

351627:CSAC RS09185
gene id: 351627:CSAC_RS09185
uniprot id: A4XKG7
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

351627:CSAC RS09035
gene id: 351627:CSAC_RS09035
uniprot id: A4XKD7
names: Similarity
messages: Belongs to the asp23 family.

351627:CSAC RS04725
gene id: 351627:CSAC_RS04725
uniprot id: A4XI10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

351627:CSAC RS13255
gene id: 351627:CSAC_RS13255
uniprot id: A4XMQ3
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

351627:CSAC RS10530
gene id: 351627:CSAC_RS10530
uniprot id: A4XL86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

351627:CSAC RS04830
gene id: 351627:CSAC_RS04830
uniprot id: A4XI31
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351627:CSAC RS13615
gene id: 351627:CSAC_RS13615
uniprot id: A4XMX1
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

351627:CSAC RS09535
gene id: 351627:CSAC_RS09535
uniprot id: A4XKN7
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

351627:CSAC RS13680
gene id: 351627:CSAC_RS13680
uniprot id: A4XMY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS12015
gene id: 351627:CSAC_RS12015
uniprot id: A4XM18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

351627:CSAC RS01540
gene id: 351627:CSAC_RS01540
uniprot id: A4XGB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

351627:CSAC RS04805
gene id: 351627:CSAC_RS04805
uniprot id: A4XI26
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS12735
gene id: 351627:CSAC_RS12735
uniprot id: A4XFX6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS14090
gene id: 351627:CSAC_RS14090
uniprot id: A4XN56
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

351627:CSAC RS04230
gene id: 351627:CSAC_RS04230
uniprot id: A4XHS0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

351627:CSAC RS08100
gene id: 351627:CSAC_RS08100
uniprot id: A4XJV7
names: Similarity
messages: Belongs to the UDPGP type 2 family.

351627:CSAC RS06600
gene id: 351627:CSAC_RS06600
uniprot id: A4XJ21
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

351627:CSAC RS14045
gene id: 351627:CSAC_RS14045
uniprot id: A4XN47
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

351627:CSAC RS12930
gene id: 351627:CSAC_RS12930
uniprot id: A4XMJ7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS03455
gene id: 351627:CSAC_RS03455
uniprot id: A4XHB8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS07720
gene id: 351627:CSAC_RS07720
uniprot id: A4XJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

351627:CSAC RS07775
gene id: 351627:CSAC_RS07775
uniprot id: A4XJP3
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04965
gene id: 351627:CSAC_RS04965
uniprot id: A4XI58
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

351627:CSAC RS11385
gene id: 351627:CSAC_RS11385
uniprot id: A4XLP4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

351627:CSAC RS03565
gene id: 351627:CSAC_RS03565
uniprot id: A4XHE0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS05935
gene id: 351627:CSAC_RS05935
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS08095
gene id: 351627:CSAC_RS08095
uniprot id: A4XJV6
names: Similarity
messages: Belongs to the UPF0473 family.

351627:CSAC RS12130
gene id: 351627:CSAC_RS12130
uniprot id: A4XM41
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

351627:CSAC RS10255
gene id: 351627:CSAC_RS10255
uniprot id: A4XL31
names: Similarity
messages: Belongs to the UPF0111 family.

351627:CSAC RS05660
gene id: 351627:CSAC_RS05660
uniprot id: A4XIJ3
names: Similarity
messages: Belongs to the glycosyl hydrolase.

351627:CSAC RS11655
gene id: 351627:CSAC_RS11655
uniprot id: A4XLU7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

351627:CSAC RS09025
gene id: 351627:CSAC_RS09025
uniprot id: A4XKD5
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

351627:CSAC RS10100
gene id: 351627:CSAC_RS10100
uniprot id: A4XL00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11980
gene id: 351627:CSAC_RS11980
uniprot id: A4XM11
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS10230
gene id: 351627:CSAC_RS10230
uniprot id: A4XL26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

351627:CSAC RS08590
gene id: 351627:CSAC_RS08590
uniprot id: A4XK51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

351627:CSAC RS12465
gene id: 351627:CSAC_RS12465
uniprot id: A4XMA8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-98 inactivates the nitrogenase reductase and regulates nitrogenase activity.

351627:CSAC RS06105
gene id: 351627:CSAC_RS06105
uniprot id: A4XIS9
names: Similarity
messages: Belongs to the glutamine synthetase family.

351627:CSAC RS06055
gene id: 351627:CSAC_RS06055
uniprot id: A4XIR9
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

351627:CSAC RS00545
gene id: 351627:CSAC_RS00545
uniprot id: A4XFS8
names: Similarity
messages: Belongs to the DHPS family.

351627:CSAC RS07600
gene id: 351627:CSAC_RS07600
uniprot id: A4XJK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

351627:CSAC RS08475
gene id: 351627:CSAC_RS08475
uniprot id: A4XK28
names: Similarity
messages: Belongs to the HepT RNase toxin family.

351627:CSAC RS02995
gene id: 351627:CSAC_RS02995
uniprot id: A4XH30
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

351627:CSAC RS13900
gene id: 351627:CSAC_RS13900
uniprot id: A4XN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS10270
gene id: 351627:CSAC_RS10270
uniprot id: A4XL34
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS10435
gene id: 351627:CSAC_RS10435
uniprot id: A4XL67
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

351627:CSAC RS02675
gene id: 351627:CSAC_RS02675
uniprot id: A4XGY0
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

351627:CSAC RS12850
gene id: 351627:CSAC_RS12850
uniprot id: A4XMI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS07900
gene id: 351627:CSAC_RS07900
uniprot id: A4XJR8
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 51 family.
messages: Homohexamer; trimer of dimers.

351627:CSAC RS05265
gene id: 351627:CSAC_RS05265
uniprot id: A4XIB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

351627:CSAC RS02250
gene id: 351627:CSAC_RS02250
uniprot id: A4XGP9
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

351627:CSAC RS10050
gene id: 351627:CSAC_RS10050
uniprot id: A4XKZ0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

351627:CSAC RS04605
gene id: 351627:CSAC_RS04605
uniprot id: A4XHY7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

351627:CSAC RS11125
gene id: 351627:CSAC_RS11125
uniprot id: A4XLJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

351627:CSAC RS05460
gene id: 351627:CSAC_RS05460
uniprot id: A4XIF5
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

351627:CSAC RS01605
gene id: 351627:CSAC_RS01605
uniprot id: A4XGC6
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

351627:CSAC RS04510
gene id: 351627:CSAC_RS04510
uniprot id: A4XHX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

351627:CSAC RS11130
gene id: 351627:CSAC_RS11130
uniprot id: A4XLK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351627:CSAC RS08865
gene id: 351627:CSAC_RS08865
uniprot id: A4XKA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

351627:CSAC RS02570
gene id: 351627:CSAC_RS02570
uniprot id: A4XGW1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS00310
gene id: 351627:CSAC_RS00310
uniprot id: A4XFN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

351627:CSAC RS06935
gene id: 351627:CSAC_RS06935
uniprot id: A4XJ88
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351627:CSAC RS12775
gene id: 351627:CSAC_RS12775
uniprot id: A4XMG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

351627:CSAC RS09195
gene id: 351627:CSAC_RS09195
uniprot id: A4XKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

351627:CSAC RS08190
gene id: 351627:CSAC_RS08190
uniprot id: A4XJX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

351627:CSAC RS02210
gene id: 351627:CSAC_RS02210
uniprot id: A4XGP1
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

351627:CSAC RS07665
gene id: 351627:CSAC_RS07665
uniprot id: A4XJM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS01805
gene id: 351627:CSAC_RS01805
uniprot id: A4XGG5
names: Similarity
messages: Belongs to the glycosyl hydrolase 43 family.

351627:CSAC RS11505
gene id: 351627:CSAC_RS11505
uniprot id: A4XLR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

351627:CSAC RS08415
gene id: 351627:CSAC_RS08415
uniprot id: A4XK17
names: Similarity
messages: Belongs to the FlgM family.

351627:CSAC RS11785
gene id: 351627:CSAC_RS11785
uniprot id: A4XLX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

351627:CSAC RS02620
gene id: 351627:CSAC_RS02620
uniprot id: A4XGX0
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS02180
gene id: 351627:CSAC_RS02180
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS10320
gene id: 351627:CSAC_RS10320
uniprot id: A4XL44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

351627:CSAC RS02415
gene id: 351627:CSAC_RS02415
uniprot id: A4XGT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

351627:CSAC RS08595
gene id: 351627:CSAC_RS08595
uniprot id: A4XK52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

351627:CSAC RS04720
gene id: 351627:CSAC_RS04720
uniprot id: A4XI09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

351627:CSAC RS10655
gene id: 351627:CSAC_RS10655
uniprot id: A4XLB2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

351627:CSAC RS12075
gene id: 351627:CSAC_RS12075
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS01790
gene id: 351627:CSAC_RS01790
uniprot id: A4XGG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

351627:CSAC RS09555
gene id: 351627:CSAC_RS09555
uniprot id: A4XKP1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

351627:CSAC RS06620
gene id: 351627:CSAC_RS06620
uniprot id: A4XJ25
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

351627:CSAC RS06275
gene id: 351627:CSAC_RS06275
uniprot id: A4XIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS09980
gene id: 351627:CSAC_RS09980
uniprot id: A4XKX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

351627:CSAC RS11490
gene id: 351627:CSAC_RS11490
uniprot id: A4XLR3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

351627:CSAC RS03475
gene id: 351627:CSAC_RS03475
uniprot id: A4XHC2
names: Subcellular Location Annotation
messages: Nucleus

351627:CSAC RS09435
gene id: 351627:CSAC_RS09435
uniprot id: A4XKL7
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

351627:CSAC RS06795
gene id: 351627:CSAC_RS06795
uniprot id: A4XJ60
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

351627:CSAC RS09220
gene id: 351627:CSAC_RS09220
uniprot id: A4XKH4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

351627:CSAC RS06720
gene id: 351627:CSAC_RS06720
uniprot id: A4XJ45
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS11565
gene id: 351627:CSAC_RS11565
uniprot id: A4XLS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

351627:CSAC RS06405
gene id: 351627:CSAC_RS06405
uniprot id: A4XIY4
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

351627:CSAC RS05855
gene id: 351627:CSAC_RS05855
uniprot id: A4XIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

351627:CSAC RS02000
gene id: 351627:CSAC_RS02000
uniprot id: A4XGK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

351627:CSAC RS00370
gene id: 351627:CSAC_RS00370
uniprot id: A4XFP6
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

351627:CSAC RS06455
gene id: 351627:CSAC_RS06455
uniprot id: A4XIZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

351627:CSAC RS00305
gene id: 351627:CSAC_RS00305
uniprot id: A4XFN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

351627:CSAC RS12485
gene id: 351627:CSAC_RS12485
uniprot id: A4XMB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm

351627:CSAC RS13640
gene id: 351627:CSAC_RS13640
uniprot id: A4XMX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS08185
gene id: 351627:CSAC_RS08185
uniprot id: A4XJX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05655
gene id: 351627:CSAC_RS05655
uniprot id: A4XIJ2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

351627:CSAC RS09325
gene id: 351627:CSAC_RS09325
uniprot id: A4XKJ5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

351627:CSAC RS11710
gene id: 351627:CSAC_RS11710
uniprot id: A4XLV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

351627:CSAC RS06205
gene id: 351627:CSAC_RS06205
uniprot id: A4XIU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

351627:CSAC RS04365
gene id: 351627:CSAC_RS04365
uniprot id: A4XHU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

351627:CSAC RS03960
gene id: 351627:CSAC_RS03960
uniprot id: A4XHL9
names: Similarity
messages: Belongs to the EamA transporter family.

351627:CSAC RS04850
gene id: 351627:CSAC_RS04850
uniprot id: A4XI35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

351627:CSAC RS11275
gene id: 351627:CSAC_RS11275
uniprot id: A4XLM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

351627:CSAC RS00495
gene id: 351627:CSAC_RS00495
uniprot id: A4XFR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

351627:CSAC RS04330
gene id: 351627:CSAC_RS04330
uniprot id: A4XHT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

351627:CSAC RS09585
gene id: 351627:CSAC_RS09585
uniprot id: A4XKP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

351627:CSAC RS01455
gene id: 351627:CSAC_RS01455
uniprot id: A4XG97
names: Similarity
messages: Belongs to the hemerythrin family.

351627:CSAC RS03010
gene id: 351627:CSAC_RS03010
uniprot id: A4XH33
names: Similarity
messages: Belongs to the peptidase S41A family.

351627:CSAC RS01815
gene id: 351627:CSAC_RS01815
uniprot id: A4XGG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

351627:CSAC RS06100
gene id: 351627:CSAC_RS06100
uniprot id: A4XIS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

351627:CSAC RS10025
gene id: 351627:CSAC_RS10025
uniprot id: A4XKY5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

351627:CSAC RS07815
gene id: 351627:CSAC_RS07815
uniprot id: A4XJQ1
names: Similarity
messages: Belongs to the HupF/HypC family.

351627:CSAC RS13200
gene id: 351627:CSAC_RS13200
uniprot id: A4XFL2
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

351627:CSAC RS11860
gene id: 351627:CSAC_RS11860
uniprot id: A4XLY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

351627:CSAC RS10095
gene id: 351627:CSAC_RS10095
uniprot id: A4XKZ9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

351627:CSAC RS08805
gene id: 351627:CSAC_RS08805
uniprot id: A4XK95
names: Similarity
messages: Belongs to the SleB family.

351627:CSAC RS11940
gene id: 351627:CSAC_RS11940
uniprot id: A4XM03
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

351627:CSAC RS08710
gene id: 351627:CSAC_RS08710
uniprot id: A4XK76
names: Similarity
messages: Belongs to the EamA transporter family.

351627:CSAC RS01280
gene id: 351627:CSAC_RS01280
uniprot id: A4XG66
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

351627:CSAC RS05275
gene id: 351627:CSAC_RS05275
uniprot id: A4XIB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

351627:CSAC RS11260
gene id: 351627:CSAC_RS11260
uniprot id: A4XLM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

351627:CSAC RS09850
gene id: 351627:CSAC_RS09850
uniprot id: A4XKV0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

351627:CSAC RS01135
gene id: 351627:CSAC_RS01135
uniprot id: A4XG37
names: Similarity
messages: Belongs to the UPF0251 family.

351627:CSAC RS13870
gene id: 351627:CSAC_RS13870
uniprot id: A4XN14
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

351627:CSAC RS00365
gene id: 351627:CSAC_RS00365
uniprot id: A4XFP5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

351627:CSAC RS11150
gene id: 351627:CSAC_RS11150
uniprot id: A4XLK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

351627:CSAC RS10875
gene id: 351627:CSAC_RS10875
uniprot id: A4XLF5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

351627:CSAC RS08910
gene id: 351627:CSAC_RS08910
uniprot id: A4XKB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

351627:CSAC RS11735
gene id: 351627:CSAC_RS11735
uniprot id: A4XLW2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

351627:CSAC RS05485
gene id: 351627:CSAC_RS05485
uniprot id: A4XIG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Cell membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

351627:CSAC RS09460
gene id: 351627:CSAC_RS09460
uniprot id: A4XKM2
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

351627:CSAC RS12795
gene id: 351627:CSAC_RS12795
uniprot id: A4XMH2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS04675
gene id: 351627:CSAC_RS04675
uniprot id: A4XI00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

351627:CSAC RS08150
gene id: 351627:CSAC_RS08150
uniprot id: A4XJW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

351627:CSAC RS09640
gene id: 351627:CSAC_RS09640
uniprot id: A4XKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

351627:CSAC RS12585
gene id: 351627:CSAC_RS12585
uniprot id: A4XMD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS00190
gene id: 351627:CSAC_RS00190
uniprot id: A4XFL2
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

351627:CSAC RS09345
gene id: 351627:CSAC_RS09345
uniprot id: A4XKJ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351627:CSAC RS11865
gene id: 351627:CSAC_RS11865
uniprot id: A4XLY8
names: Similarity
messages: Belongs to the CdaR family.

351627:CSAC RS10075
gene id: 351627:CSAC_RS10075
uniprot id: A4XKZ5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

351627:CSAC RS03025
gene id: 351627:CSAC_RS03025
uniprot id: A4XH36
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

351627:CSAC RS08845
gene id: 351627:CSAC_RS08845
uniprot id: A4XKA2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

351627:CSAC RS08825
gene id: 351627:CSAC_RS08825
uniprot id: A4XK98
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

351627:CSAC RS09810
gene id: 351627:CSAC_RS09810
uniprot id: A4XKU2
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04610
gene id: 351627:CSAC_RS04610
uniprot id: A4XHY8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

351627:CSAC RS05095
gene id: 351627:CSAC_RS05095
uniprot id: A4XI84
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351627:CSAC RS07945
gene id: 351627:CSAC_RS07945
uniprot id: A4XJS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

351627:CSAC RS01355
gene id: 351627:CSAC_RS01355
uniprot id: A4XG82
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS12720
gene id: 351627:CSAC_RS12720
uniprot id: A4XMG0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS03075
gene id: 351627:CSAC_RS03075
uniprot id: A4XH45
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

351627:CSAC RS09175
gene id: 351627:CSAC_RS09175
uniprot id: A4XKG5
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

351627:CSAC RS01640
gene id: 351627:CSAC_RS01640
uniprot id: A4XFN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

351627:CSAC RS00960
gene id: 351627:CSAC_RS00960
uniprot id: A4XG02
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

351627:CSAC RS08015
gene id: 351627:CSAC_RS08015
uniprot id: A4XJU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

351627:CSAC RS09975
gene id: 351627:CSAC_RS09975
uniprot id: A4XKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

351627:CSAC RS07440
gene id: 351627:CSAC_RS07440
uniprot id: A4XJI1
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

351627:CSAC RS07435
gene id: 351627:CSAC_RS07435
uniprot id: A4XJI0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

351627:CSAC RS04885
gene id: 351627:CSAC_RS04885
uniprot id: A4XI42
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10445
gene id: 351627:CSAC_RS10445
uniprot id: A4XL69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

351627:CSAC RS11225
gene id: 351627:CSAC_RS11225
uniprot id: A4XLL8
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

351627:CSAC RS06940
gene id: 351627:CSAC_RS06940
uniprot id: A4XJ89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

351627:CSAC RS06865
gene id: 351627:CSAC_RS06865
uniprot id: A4XJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS01905
gene id: 351627:CSAC_RS01905
uniprot id: A4XGI5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

351627:CSAC RS01035
gene id: 351627:CSAC_RS01035
uniprot id: A4XG17
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

351627:CSAC RS04425
gene id: 351627:CSAC_RS04425
uniprot id: A4XHV7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

351627:CSAC RS00630
gene id: 351627:CSAC_RS00630
uniprot id: A4XFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS12160
gene id: 351627:CSAC_RS12160
uniprot id: A4XM47
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

351627:CSAC RS02665
gene id: 351627:CSAC_RS02665
uniprot id: A4XGX8
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04660
gene id: 351627:CSAC_RS04660
uniprot id: A4XHZ7
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS08125
gene id: 351627:CSAC_RS08125
uniprot id: A4XJW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

351627:CSAC RS08990
gene id: 351627:CSAC_RS08990
uniprot id: A4XKC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

351627:CSAC RS11195
gene id: 351627:CSAC_RS11195
uniprot id: A4XLL4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS06420
gene id: 351627:CSAC_RS06420
uniprot id: A4XIY7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

351627:CSAC RS08290
gene id: 351627:CSAC_RS08290
uniprot id: A4XJZ3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

351627:CSAC RS02230
gene id: 351627:CSAC_RS02230
uniprot id: A4XGP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS04760
gene id: 351627:CSAC_RS04760
uniprot id: A4XI17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

351627:CSAC RS10850
gene id: 351627:CSAC_RS10850
uniprot id: A4XLF0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

351627:CSAC RS06540
gene id: 351627:CSAC_RS06540
uniprot id: A4XJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

351627:CSAC RS11500
gene id: 351627:CSAC_RS11500
uniprot id: A4XLR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

351627:CSAC RS04065
gene id: 351627:CSAC_RS04065
uniprot id: A4XHN9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04185
gene id: 351627:CSAC_RS04185
uniprot id: A4XHR1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS05270
gene id: 351627:CSAC_RS05270
uniprot id: A4XIB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

351627:CSAC RS01325
gene id: 351627:CSAC_RS01325
uniprot id: A4XG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS04985
gene id: 351627:CSAC_RS04985
uniprot id: A4XI62
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS09350
gene id: 351627:CSAC_RS09350
uniprot id: A4XKK0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

351627:CSAC RS09945
gene id: 351627:CSAC_RS09945
uniprot id: A4XKW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

351627:CSAC RS09755
gene id: 351627:CSAC_RS09755
uniprot id: A4XKT1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

351627:CSAC RS13740
gene id: 351627:CSAC_RS13740
uniprot id: A4XMZ3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

351627:CSAC RS04615
gene id: 351627:CSAC_RS04615
uniprot id: A4XHY9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

351627:CSAC RS13425
gene id: 351627:CSAC_RS13425
uniprot id: A4XMT4
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

351627:CSAC RS07480
gene id: 351627:CSAC_RS07480
uniprot id: A4XJI9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS14080
gene id: 351627:CSAC_RS14080
uniprot id: A4XN54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

351627:CSAC RS09200
gene id: 351627:CSAC_RS09200
uniprot id: A4XKH0
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

351627:CSAC RS03710
gene id: 351627:CSAC_RS03710
uniprot id: A4XHH0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

351627:CSAC RS10060
gene id: 351627:CSAC_RS10060
uniprot id: A4XKZ2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

351627:CSAC RS05585
gene id: 351627:CSAC_RS05585
uniprot id: A4XIH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

351627:CSAC RS06290
gene id: 351627:CSAC_RS06290
uniprot id: A4XIW1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

351627:CSAC RS02035
gene id: 351627:CSAC_RS02035
uniprot id: A4XGK9
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04145
gene id: 351627:CSAC_RS04145
uniprot id: A4XHQ3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS04680
gene id: 351627:CSAC_RS04680
uniprot id: A4XI01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

351627:CSAC RS08725
gene id: 351627:CSAC_RS08725
uniprot id: A4XK79
names: Similarity
messages: Belongs to the thioredoxin family.

351627:CSAC RS05510
gene id: 351627:CSAC_RS05510
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS11970
gene id: 351627:CSAC_RS11970
uniprot id: A4XM09
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

351627:CSAC RS08905
gene id: 351627:CSAC_RS08905
uniprot id: A4XKB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

351627:CSAC RS10020
gene id: 351627:CSAC_RS10020
uniprot id: A4XKY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

351627:CSAC RS08860
gene id: 351627:CSAC_RS08860
uniprot id: A4XKA5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

351627:CSAC RS12785
gene id: 351627:CSAC_RS12785
uniprot id: A4XMH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11825
gene id: 351627:CSAC_RS11825
uniprot id: A4XLY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

351627:CSAC RS03190
gene id: 351627:CSAC_RS03190
uniprot id: A4XH67
names: Similarity
messages: Belongs to the UPF0175 family.

351627:CSAC RS04670
gene id: 351627:CSAC_RS04670
uniprot id: A4XHZ9
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS08880
gene id: 351627:CSAC_RS08880
uniprot id: A4XKA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

351627:CSAC RS13040
gene id: 351627:CSAC_RS13040
uniprot id: A4XML4
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS13140
gene id: 351627:CSAC_RS13140
uniprot id: A4XMN2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351627:CSAC RS01520
gene id: 351627:CSAC_RS01520
uniprot id: A4XGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS03635
gene id: 351627:CSAC_RS03635
uniprot id: A4XHF5
names: Similarity
messages: Belongs to the ribulokinase family.

351627:CSAC RS08355
gene id: 351627:CSAC_RS08355
uniprot id: A4XK06
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

351627:CSAC RS03940
gene id: 351627:CSAC_RS03940
uniprot id: A4XHL5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

351627:CSAC RS03015
gene id: 351627:CSAC_RS03015
uniprot id: A4XH34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS01215
gene id: 351627:CSAC_RS01215
uniprot id: A4XG53
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS11095
gene id: 351627:CSAC_RS11095
uniprot id: A4XLJ3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

351627:CSAC RS06150
gene id: 351627:CSAC_RS06150
uniprot id: A4XIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

351627:CSAC RS06650
gene id: 351627:CSAC_RS06650
uniprot id: A4XJ31
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

351627:CSAC RS13990
gene id: 351627:CSAC_RS13990
uniprot id: A4XN36
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

351627:CSAC RS06850
gene id: 351627:CSAC_RS06850
uniprot id: A4XJ71
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

351627:CSAC RS09135
gene id: 351627:CSAC_RS09135
uniprot id: A4XKF7
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS00375
gene id: 351627:CSAC_RS00375
uniprot id: A4XFP7
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

351627:CSAC RS07930
gene id: 351627:CSAC_RS07930
uniprot id: A4XJS4
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

351627:CSAC RS11765
gene id: 351627:CSAC_RS11765
uniprot id: A4XLW8
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

351627:CSAC RS11380
gene id: 351627:CSAC_RS11380
uniprot id: A4XLP3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

351627:CSAC RS05030
gene id: 351627:CSAC_RS05030
uniprot id: A4XI71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

351627:CSAC RS04030
gene id: 351627:CSAC_RS04030
uniprot id: A4XHN2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

351627:CSAC RS09870
gene id: 351627:CSAC_RS09870
uniprot id: A4XKV4
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

351627:CSAC RS03995
gene id: 351627:CSAC_RS03995
uniprot id: A4XHM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

351627:CSAC RS10785
gene id: 351627:CSAC_RS10785
uniprot id: A4XLD7
names: Similarity
messages: Belongs to the CinA family.

351627:CSAC RS08645
gene id: 351627:CSAC_RS08645
uniprot id: A4XK62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

351627:CSAC RS10340
gene id: 351627:CSAC_RS10340
uniprot id: A4XL48
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS06945
gene id: 351627:CSAC_RS06945
uniprot id: A4XJ90
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

351627:CSAC RS01570
gene id: 351627:CSAC_RS01570
uniprot id: A4XGB8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

351627:CSAC RS14195
gene id: 351627:CSAC_RS14195
uniprot id: A4XJ47
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS04445
gene id: 351627:CSAC_RS04445
uniprot id: A4XHW1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

351627:CSAC RS09400
gene id: 351627:CSAC_RS09400
uniprot id: A4XKL0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

351627:CSAC RS05025
gene id: 351627:CSAC_RS05025
uniprot id: A4XI70
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

351627:CSAC RS14100
gene id: 351627:CSAC_RS14100
uniprot id: A4XN58
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

351627:CSAC RS08140
gene id: 351627:CSAC_RS08140
uniprot id: A4XJW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

351627:CSAC RS04890
gene id: 351627:CSAC_RS04890
uniprot id: A4XI43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

351627:CSAC RS10300
gene id: 351627:CSAC_RS10300
uniprot id: A4XL40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

351627:CSAC RS09415
gene id: 351627:CSAC_RS09415
uniprot id: A4XKL3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

351627:CSAC RS08110
gene id: 351627:CSAC_RS08110
uniprot id: A4XJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

351627:CSAC RS03310
gene id: 351627:CSAC_RS03310
uniprot id: A4XH90
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS05910
gene id: 351627:CSAC_RS05910
uniprot id: A4XIP0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS08310
gene id: 351627:CSAC_RS08310
uniprot id: A4XJZ7
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

351627:CSAC RS05550
gene id: 351627:CSAC_RS05550
uniprot id: A4XIH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

351627:CSAC RS09265
gene id: 351627:CSAC_RS09265
uniprot id: A4XKI3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

351627:CSAC RS01015
gene id: 351627:CSAC_RS01015
uniprot id: A4XG13
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

351627:CSAC RS08875
gene id: 351627:CSAC_RS08875
uniprot id: A4XKA8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS09130
gene id: 351627:CSAC_RS09130
uniprot id: A4XKF6
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS12225
gene id: 351627:CSAC_RS12225
uniprot id: A4XM60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS00160
gene id: 351627:CSAC_RS00160
uniprot id: A4XFK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

351627:CSAC RS06015
gene id: 351627:CSAC_RS06015
uniprot id: A4XIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

351627:CSAC RS08115
gene id: 351627:CSAC_RS08115
uniprot id: A4XJW0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

351627:CSAC RS10210
gene id: 351627:CSAC_RS10210
uniprot id: A4XL22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

351627:CSAC RS12110
gene id: 351627:CSAC_RS12110
uniprot id: A4XM37
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

351627:CSAC RS09320
gene id: 351627:CSAC_RS09320
uniprot id: A4XKJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

351627:CSAC RS07800
gene id: 351627:CSAC_RS07800
uniprot id: A4XJP8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

351627:CSAC RS09950
gene id: 351627:CSAC_RS09950
uniprot id: A4XKX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

351627:CSAC RS06060
gene id: 351627:CSAC_RS06060
uniprot id: A4XIS0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

351627:CSAC RS07450
gene id: 351627:CSAC_RS07450
uniprot id: A4XJI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

351627:CSAC RS10310
gene id: 351627:CSAC_RS10310
uniprot id: A4XL42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

351627:CSAC RS13755
gene id: 351627:CSAC_RS13755
uniprot id: A4XMZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

351627:CSAC RS03405
gene id: 351627:CSAC_RS03405
uniprot id: A4XHA8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

351627:CSAC RS11580
gene id: 351627:CSAC_RS11580
uniprot id: A4XLT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

351627:CSAC RS01935
gene id: 351627:CSAC_RS01935
uniprot id: A4XGJ1
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

351627:CSAC RS10870
gene id: 351627:CSAC_RS10870
uniprot id: A4XLF4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

351627:CSAC RS05515
gene id: 351627:CSAC_RS05515
uniprot id: A4XIG6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

351627:CSAC RS07430
gene id: 351627:CSAC_RS07430
uniprot id: A4XJH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

351627:CSAC RS10680
gene id: 351627:CSAC_RS10680
uniprot id: A4XLB7
names: Subcellular Location Annotation
messages: Cell membrane

351627:CSAC RS11990
gene id: 351627:CSAC_RS11990
uniprot id: A4XM13
names: Similarity
messages: Belongs to the CtsR family.

351627:CSAC RS09900
gene id: 351627:CSAC_RS09900
uniprot id: A4XKW0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS01000
gene id: 351627:CSAC_RS01000
uniprot id: A4XG10
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

351627:CSAC RS04845
gene id: 351627:CSAC_RS04845
uniprot id: A4XI34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

351627:CSAC RS11175
gene id: 351627:CSAC_RS11175
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS11520
gene id: 351627:CSAC_RS11520
uniprot id: A4XLR9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

351627:CSAC RS02350
gene id: 351627:CSAC_RS02350
uniprot id: A4XGR8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

351627:CSAC RS06970
gene id: 351627:CSAC_RS06970
uniprot id: A4XJ95
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS03575
gene id: 351627:CSAC_RS03575
uniprot id: A4XHE2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS12860
gene id: 351627:CSAC_RS12860
uniprot id: A4XMI3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS06755
gene id: 351627:CSAC_RS06755
uniprot id: A4XJ52
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

351627:CSAC RS07650
gene id: 351627:CSAC_RS07650
uniprot id: A4XJL8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

351627:CSAC RS10195
gene id: 351627:CSAC_RS10195
uniprot id: A4XL19
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

351627:CSAC RS09545
gene id: 351627:CSAC_RS09545
uniprot id: A4XKN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

351627:CSAC RS06780
gene id: 351627:CSAC_RS06780
uniprot id: A4XJ57
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

351627:CSAC RS04650
gene id: 351627:CSAC_RS04650
uniprot id: A4XHZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

351627:CSAC RS06560
gene id: 351627:CSAC_RS06560
uniprot id: A4XJ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS02505
gene id: 351627:CSAC_RS02505
uniprot id: A4XGU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

351627:CSAC RS10010
gene id: 351627:CSAC_RS10010
uniprot id: A4XKY2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

351627:CSAC RS07885
gene id: 351627:CSAC_RS07885
uniprot id: A4XJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11305
gene id: 351627:CSAC_RS11305
uniprot id: A4XLN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS06965
gene id: 351627:CSAC_RS06965
uniprot id: A4XJ94
names: Similarity
messages: Belongs to the glutamate synthase family.

351627:CSAC RS09225
gene id: 351627:CSAC_RS09225
uniprot id: A4XKH5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

351627:CSAC RS02520
gene id: 351627:CSAC_RS02520
uniprot id: A4XGV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS12790
gene id: 351627:CSAC_RS12790
uniprot id: A4XMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11545
gene id: 351627:CSAC_RS11545
uniprot id: A4XLS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

351627:CSAC RS04915
gene id: 351627:CSAC_RS04915
uniprot id: A4XI48
names: Similarity
messages: Belongs to the AOR/FOR family.

351627:CSAC RS00005
gene id: 351627:CSAC_RS00005
uniprot id: A4XFI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

351627:CSAC RS14070
gene id: 351627:CSAC_RS14070
uniprot id: A4XN52
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

351627:CSAC RS08055
gene id: 351627:CSAC_RS08055
uniprot id: A4XJU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

351627:CSAC RS11015
gene id: 351627:CSAC_RS11015
uniprot id: A4XLI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS09765
gene id: 351627:CSAC_RS09765
uniprot id: A4XKT3
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

351627:CSAC RS02100
gene id: 351627:CSAC_RS02100
uniprot id: A4XGM2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS06585
gene id: 351627:CSAC_RS06585
uniprot id: A4XJ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

351627:CSAC RS08980
gene id: 351627:CSAC_RS08980
uniprot id: A4XKC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

351627:CSAC RS10275
gene id: 351627:CSAC_RS10275
uniprot id: A4XL35
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

351627:CSAC RS01560
gene id: 351627:CSAC_RS01560
uniprot id: A4XGB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS11435
gene id: 351627:CSAC_RS11435
uniprot id: A4XLQ2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

351627:CSAC RS08460
gene id: 351627:CSAC_RS08460
uniprot id: A4XK25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

351627:CSAC RS12200
gene id: 351627:CSAC_RS12200
uniprot id: A4XM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS11885
gene id: 351627:CSAC_RS11885
uniprot id: A4XLZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

351627:CSAC RS02215
gene id: 351627:CSAC_RS02215
uniprot id: A4XGP2
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

351627:CSAC RS14005
gene id: 351627:CSAC_RS14005
uniprot id: A4XN39
names: Similarity
messages: Belongs to the class-I fumarase family.

351627:CSAC RS02150
gene id: 351627:CSAC_RS02150
uniprot id: A4XGN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS01115
gene id: 351627:CSAC_RS01115
uniprot id: A4XG33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

351627:CSAC RS08425
gene id: 351627:CSAC_RS08425
uniprot id: A4XK19
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

351627:CSAC RS00620
gene id: 351627:CSAC_RS00620
uniprot id: A4XFU3
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10930
gene id: 351627:CSAC_RS10930
uniprot id: A4XLG7
names: Similarity
messages: Belongs to the intimin/invasin family.

351627:CSAC RS00380
gene id: 351627:CSAC_RS00380
uniprot id: A4XFP8
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

351627:CSAC RS03510
gene id: 351627:CSAC_RS03510
uniprot id: A4XHC9
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.
messages: Transcriptional repressor of xylose-utilizing enzymes.

351627:CSAC RS01005
gene id: 351627:CSAC_RS01005
uniprot id: A4XG11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

351627:CSAC RS05135
gene id: 351627:CSAC_RS05135
uniprot id: A4XI92
names: Similarity
messages: Belongs to the EamA transporter family.

351627:CSAC RS11240
gene id: 351627:CSAC_RS11240
uniprot id: A4XLM0
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

351627:CSAC RS08320
gene id: 351627:CSAC_RS08320
uniprot id: A4XJZ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

351627:CSAC RS00040
gene id: 351627:CSAC_RS00040
uniprot id: A4XFI8
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351627:CSAC RS04755
gene id: 351627:CSAC_RS04755
uniprot id: A4XI16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS10770
gene id: 351627:CSAC_RS10770
uniprot id: A4XLD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

351627:CSAC RS05775
gene id: 351627:CSAC_RS05775
uniprot id: A4XIL7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

351627:CSAC RS05225
gene id: 351627:CSAC_RS05225
uniprot id: A4XIA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS06305
gene id: 351627:CSAC_RS06305
uniprot id: A4XIW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

351627:CSAC RS06080
gene id: 351627:CSAC_RS06080
uniprot id: A4XIS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

351627:CSAC RS07535
gene id: 351627:CSAC_RS07535
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS00995
gene id: 351627:CSAC_RS00995
uniprot id: A4XG09
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

351627:CSAC RS09865
gene id: 351627:CSAC_RS09865
uniprot id: A4XKV3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

351627:CSAC RS02630
gene id: 351627:CSAC_RS02630
uniprot id: A4XGX2
names: Subcellular Location Annotation
messages: Secreted

351627:CSAC RS14065
gene id: 351627:CSAC_RS14065
uniprot id: A4XN51
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

351627:CSAC RS09565
gene id: 351627:CSAC_RS09565
uniprot id: A4XKP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351627:CSAC RS08920
gene id: 351627:CSAC_RS08920
uniprot id: A4XKB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

351627:CSAC RS07085
gene id: 351627:CSAC_RS07085
uniprot id: A4XJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

351627:CSAC RS05050
gene id: 351627:CSAC_RS05050
uniprot id: A4XI75
names: Similarity
messages: Belongs to the GerABKA family.

351627:CSAC RS07740
gene id: 351627:CSAC_RS07740
uniprot id: A4XJN6
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

351627:CSAC RS07780
gene id: 351627:CSAC_RS07780
uniprot id: A4XJP4
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

351627:CSAC RS06180
gene id: 351627:CSAC_RS06180
uniprot id: A4XIU3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

351627:CSAC RS10855
gene id: 351627:CSAC_RS10855
uniprot id: A4XLF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

351627:CSAC RS04410
gene id: 351627:CSAC_RS04410
uniprot id: A4XHV4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

351627:CSAC RS11460
gene id: 351627:CSAC_RS11460
uniprot id: A4XLQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

351627:CSAC RS02965
gene id: 351627:CSAC_RS02965
uniprot id: A4XH24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

351627:CSAC RS08210
gene id: 351627:CSAC_RS08210
uniprot id: A4XJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

351627:CSAC RS13340
gene id: 351627:CSAC_RS13340
uniprot id: A4XMR7
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

351627:CSAC RS10460
gene id: 351627:CSAC_RS10460
uniprot id: A4XL72
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

351627:CSAC RS01780
gene id: 351627:CSAC_RS01780
uniprot id: A4XGG0
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

351627:CSAC RS08630
gene id: 351627:CSAC_RS08630
uniprot id: A4XK59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

351627:CSAC RS06155
gene id: 351627:CSAC_RS06155
uniprot id: A4XIT9
names: Similarity
messages: Belongs to the threonine synthase family.

351627:CSAC RS00030
gene id: 351627:CSAC_RS00030
uniprot id: A4XFI6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351627:CSAC RS09115
gene id: 351627:CSAC_RS09115
uniprot id: A4XKF3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

351627:CSAC RS12115
gene id: 351627:CSAC_RS12115
uniprot id: A4XM38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

351627:CSAC RS04640
gene id: 351627:CSAC_RS04640
uniprot id: A4XHZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

351627:CSAC RS08560
gene id: 351627:CSAC_RS08560
uniprot id: A4XK45
names: Similarity
messages: Belongs to the SecB family.

351627:CSAC RS00640
gene id: 351627:CSAC_RS00640
uniprot id: A4XFU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Monomer.

351627:CSAC RS14050
gene id: 351627:CSAC_RS14050
uniprot id: A4XN48
names: Similarity
messages: Belongs to the ParB family.

351627:CSAC RS02825
gene id: 351627:CSAC_RS02825
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS12905
gene id: 351627:CSAC_RS12905
uniprot id: A4XMJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05220
gene id: 351627:CSAC_RS05220
uniprot id: A4XIA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS03865
gene id: 351627:CSAC_RS03865
uniprot id: A4XHK0
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS08950
gene id: 351627:CSAC_RS08950
uniprot id: A4XKC0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

351627:CSAC RS04440
gene id: 351627:CSAC_RS04440
uniprot id: A4XHW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

351627:CSAC RS12675
gene id: 351627:CSAC_RS12675
uniprot id: A4XMF1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS03885
gene id: 351627:CSAC_RS03885
uniprot id: A4XHK4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS09465
gene id: 351627:CSAC_RS09465
uniprot id: A4XKM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

351627:CSAC RS03130
gene id: 351627:CSAC_RS03130
uniprot id: A4XH56
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

351627:CSAC RS01225
gene id: 351627:CSAC_RS01225
uniprot id: A4XG55
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351627:CSAC RS08635
gene id: 351627:CSAC_RS08635
uniprot id: A4XK60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

351627:CSAC RS01295
gene id: 351627:CSAC_RS01295
uniprot id: A4XG69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

351627:CSAC RS10450
gene id: 351627:CSAC_RS10450
uniprot id: A4XL70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

351627:CSAC RS03420
gene id: 351627:CSAC_RS03420
uniprot id: A4XHB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS00025
gene id: 351627:CSAC_RS00025
uniprot id: A4XFI5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351627:CSAC RS13315
gene id: 351627:CSAC_RS13315
uniprot id: A4XMR4
names: Similarity
messages: Belongs to the peptidase A24 family.

351627:CSAC RS10395
gene id: 351627:CSAC_RS10395
uniprot id: A4XL59
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

351627:CSAC RS01750
gene id: 351627:CSAC_RS01750
uniprot id: A4XGF4
names: Similarity
messages: Belongs to the FGGY kinase family.

351627:CSAC RS06330
gene id: 351627:CSAC_RS06330
uniprot id: A4XIW9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

351627:CSAC RS09760
gene id: 351627:CSAC_RS09760
uniprot id: A4XKT2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

351627:CSAC RS05210
gene id: 351627:CSAC_RS05210
uniprot id: A4XIA5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

351627:CSAC RS11090
gene id: 351627:CSAC_RS11090
uniprot id: A4XLJ2
names: Similarity
messages: Belongs to the asp23 family.

351627:CSAC RS07935
gene id: 351627:CSAC_RS07935
uniprot id: A4XJS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

351627:CSAC RS05760
gene id: 351627:CSAC_RS05760
uniprot id: A4XIL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

351627:CSAC RS09590
gene id: 351627:CSAC_RS09590
uniprot id: A4XKP8
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

351627:CSAC RS09970
gene id: 351627:CSAC_RS09970
uniprot id: A4XKX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

351627:CSAC RS00520
gene id: 351627:CSAC_RS00520
uniprot id: A4XFS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS02310
gene id: 351627:CSAC_RS02310
uniprot id: A4XGR1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

351627:CSAC RS02970
gene id: 351627:CSAC_RS02970
uniprot id: A4XH25
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS04665
gene id: 351627:CSAC_RS04665
uniprot id: A4XHZ8
names: Similarity
messages: Belongs to the transpeptidase family.

351627:CSAC RS00875
gene id: 351627:CSAC_RS00875
uniprot id: A4XFY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

351627:CSAC RS04595
gene id: 351627:CSAC_RS04595
uniprot id: A4XHY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

351627:CSAC RS05970
gene id: 351627:CSAC_RS05970
uniprot id: A4XIQ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

351627:CSAC RS02590
gene id: 351627:CSAC_RS02590
uniprot id: A4XGW5
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04055
gene id: 351627:CSAC_RS04055
uniprot id: A4XHN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS08870
gene id: 351627:CSAC_RS08870
uniprot id: A4XKA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

351627:CSAC RS07700
gene id: 351627:CSAC_RS07700
uniprot id: A4XJM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351627:CSAC RS02770
gene id: 351627:CSAC_RS02770
uniprot id: A4XGZ2
names: Similarity
messages: Belongs to the glutamate synthase family.

351627:CSAC RS13630
gene id: 351627:CSAC_RS13630
uniprot id: A4XMX4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS06350
gene id: 351627:CSAC_RS06350
uniprot id: A4XIX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

351627:CSAC RS13410
gene id: 351627:CSAC_RS13410
uniprot id: A4XMT1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

351627:CSAC RS12480
gene id: 351627:CSAC_RS12480
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS01775
gene id: 351627:CSAC_RS01775
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS03945
gene id: 351627:CSAC_RS03945
uniprot id: A4XHL6
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

351627:CSAC RS11670
gene id: 351627:CSAC_RS11670
uniprot id: A4XLV0
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS04220
gene id: 351627:CSAC_RS04220
uniprot id: A4XHR8
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS04350
gene id: 351627:CSAC_RS04350
uniprot id: A4XHU2
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS07970
gene id: 351627:CSAC_RS07970
uniprot id: A4XJT1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351627:CSAC RS12590
gene id: 351627:CSAC_RS12590
uniprot id: A4XMD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05340
gene id: 351627:CSAC_RS05340
uniprot id: A4XID1
names: Similarity
messages: Belongs to the peptidase C40 family.

351627:CSAC RS07225
gene id: 351627:CSAC_RS07225
uniprot id: A4XJD9
names: Similarity
messages: Belongs to the peptidase A24 family.

351627:CSAC RS03505
gene id: 351627:CSAC_RS03505
uniprot id: A4XHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05200
gene id: 351627:CSAC_RS05200
uniprot id: A4XIA3
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS10040
gene id: 351627:CSAC_RS10040
uniprot id: A4XKY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

351627:CSAC RS04685
gene id: 351627:CSAC_RS04685
uniprot id: A4XI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

351627:CSAC RS07460
gene id: 351627:CSAC_RS07460
uniprot id: A4XJI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS01085
gene id: 351627:CSAC_RS01085
uniprot id: A4XG27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

351627:CSAC RS06915
gene id: 351627:CSAC_RS06915
uniprot id: A4XJ84
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

351627:CSAC RS09370
gene id: 351627:CSAC_RS09370
uniprot id: A4XKK4
names: Similarity
messages: Belongs to the TlyA family.

351627:CSAC RS06450
gene id: 351627:CSAC_RS06450
uniprot id: A4XIZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

351627:CSAC RS12205
gene id: 351627:CSAC_RS12205
uniprot id: A4XM56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS07245
gene id: 351627:CSAC_RS07245
uniprot id: A4XJE4
names: Similarity
messages: Belongs to the GSP E family.

351627:CSAC RS03680
gene id: 351627:CSAC_RS03680
uniprot id: A4XHG4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS11295
gene id: 351627:CSAC_RS11295
uniprot id: A4XLN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

351627:CSAC RS09895
gene id: 351627:CSAC_RS09895
uniprot id: A4XKV9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

351627:CSAC RS06440
gene id: 351627:CSAC_RS06440
uniprot id: A4XIZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

351627:CSAC RS10715
gene id: 351627:CSAC_RS10715
uniprot id: A4XLC3
names: Similarity
messages: Belongs to the asp23 family.

351627:CSAC RS13585
gene id: 351627:CSAC_RS13585
uniprot id: A4XMW7
names: Similarity
messages: Belongs to the NadC/ModD family.

351627:CSAC RS07020
gene id: 351627:CSAC_RS07020
uniprot id: A4XJA5
names: Similarity
messages: Belongs to the Rpn/YhgA-like nuclease family.

351627:CSAC RS10705
gene id: 351627:CSAC_RS10705
uniprot id: A4XLC1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

351627:CSAC RS01980
gene id: 351627:CSAC_RS01980
uniprot id: A4XGJ8
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS11925
gene id: 351627:CSAC_RS11925
uniprot id: A4XM00
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

351627:CSAC RS04225
gene id: 351627:CSAC_RS04225
uniprot id: A4XHR9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

351627:CSAC RS09750
gene id: 351627:CSAC_RS09750
uniprot id: A4XKT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

351627:CSAC RS12325
gene id: 351627:CSAC_RS12325
uniprot id: A4XM80
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

351627:CSAC RS07990
gene id: 351627:CSAC_RS07990
uniprot id: A4XJT5
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS13220
gene id: 351627:CSAC_RS13220
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS12515
gene id: 351627:CSAC_RS12515
uniprot id: A4XMB8
names: Similarity
messages: Belongs to the P(II) protein family.

351627:CSAC RS09030
gene id: 351627:CSAC_RS09030
uniprot id: A4XKD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

351627:CSAC RS06465
gene id: 351627:CSAC_RS06465
uniprot id: A4XIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

351627:CSAC RS06445
gene id: 351627:CSAC_RS06445
uniprot id: A4XIZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

351627:CSAC RS07950
gene id: 351627:CSAC_RS07950
uniprot id: A4XJS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS04345
gene id: 351627:CSAC_RS04345
uniprot id: A4XHU1
names: Similarity
messages: Belongs to the RecJ family.

351627:CSAC RS06120
gene id: 351627:CSAC_RS06120
uniprot id: A4XIT2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

351627:CSAC RS09570
gene id: 351627:CSAC_RS09570
uniprot id: A4XKP4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

351627:CSAC RS03890
gene id: 351627:CSAC_RS03890
uniprot id: A4XHK5
names: Similarity
messages: Belongs to the UPF0145 family.

351627:CSAC RS10235
gene id: 351627:CSAC_RS10235
uniprot id: A4XL27
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

351627:CSAC RS09430
gene id: 351627:CSAC_RS09430
uniprot id: A4XKL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

351627:CSAC RS11245
gene id: 351627:CSAC_RS11245
uniprot id: A4XLM1
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS01500
gene id: 351627:CSAC_RS01500
uniprot id: A4XGA6
names: Function
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.
messages: Belongs to the cellobiose 2-epimerase family.
messages: Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man).

351627:CSAC RS00990
gene id: 351627:CSAC_RS00990
uniprot id: A4XG08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. NagD family.
messages: Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro.
messages: Divalent metal ions. Mg(2+) is the most effective.

351627:CSAC RS12815
gene id: 351627:CSAC_RS12815
uniprot id: A4XMH5
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

351627:CSAC RS08035
gene id: 351627:CSAC_RS08035
uniprot id: A4XJU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

351627:CSAC RS03895
gene id: 351627:CSAC_RS03895
uniprot id: A4XHK6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351627:CSAC RS09260
gene id: 351627:CSAC_RS09260
uniprot id: A4XKI2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

351627:CSAC RS05870
gene id: 351627:CSAC_RS05870
uniprot id: A4XIN2
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

351627:CSAC RS11470
gene id: 351627:CSAC_RS11470
uniprot id: A4XLQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

351627:CSAC RS11450
gene id: 351627:CSAC_RS11450
uniprot id: A4XLQ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

351627:CSAC RS05520
gene id: 351627:CSAC_RS05520
uniprot id: A4XIG7
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

351627:CSAC RS10205
gene id: 351627:CSAC_RS10205
uniprot id: A4XL21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

351627:CSAC RS12450
gene id: 351627:CSAC_RS12450
uniprot id: A4XMA5
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

351627:CSAC RS06775
gene id: 351627:CSAC_RS06775
uniprot id: A4XJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

351627:CSAC RS08065
gene id: 351627:CSAC_RS08065
uniprot id: A4XJV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

351627:CSAC RS05000
gene id: 351627:CSAC_RS05000
uniprot id: A4XI65
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

351627:CSAC RS04935
gene id: 351627:CSAC_RS04935
uniprot id: A4XI52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS13805
gene id: 351627:CSAC_RS13805
uniprot id: A4XN02
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the KduI family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.

351627:CSAC RS11750
gene id: 351627:CSAC_RS11750
uniprot id: A4XLW5
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS13590
gene id: 351627:CSAC_RS13590
uniprot id: A4XMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05650
gene id: 351627:CSAC_RS05650
uniprot id: A4XIJ1
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS02360
gene id: 351627:CSAC_RS02360
uniprot id: A4XGS0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351627:CSAC RS13205
gene id: 351627:CSAC_RS13205
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS08000
gene id: 351627:CSAC_RS08000
uniprot id: A4XJT7
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Both the DNA unwinding and positive supercoiling activities require the cooperation of both domains. The cooperative action between the helicase-like and the topoisomerase domains is specific. The helicase-like domain probably does not directly unwind DNA but acts more likely by driving ATP-dependent conformational changes within the whole enzyme, functioning more like a protein motor. The 'latch' region of the N-terminal domain plays a regulatory role in the enzyme, repressing topoisomerase activity in the absence of ATP and therefore preventing the enzyme from acting as an ATP-independent relaxing enzyme; it also helps to coordinate nucleotide hydrolysis by the ATPase domain with the supercoiling activity of the topoisomerase domain.
messages: In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
messages: In the N-terminal section; belongs to the DEAD box helicase family. DDVD subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication.
messages: Monomer.
messages: This enzyme is the only unique feature of hyperthermophilic bacteria/archaea discovered so far. It appears to be essential for adaptation to life at high temperatures.

351627:CSAC RS09340
gene id: 351627:CSAC_RS09340
uniprot id: A4XKJ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351627:CSAC RS12900
gene id: 351627:CSAC_RS12900
uniprot id: A4XMJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS06725
gene id: 351627:CSAC_RS06725
uniprot id: A4XJ46
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS12340
gene id: 351627:CSAC_RS12340
uniprot id: A4XM83
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

351627:CSAC RS04240
gene id: 351627:CSAC_RS04240
uniprot id: A4XFL2
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

351627:CSAC RS14040
gene id: 351627:CSAC_RS14040
uniprot id: A4XN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

351627:CSAC RS07925
gene id: 351627:CSAC_RS07925
uniprot id: A4XJS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

351627:CSAC RS06815
gene id: 351627:CSAC_RS06815
uniprot id: A4XJ64
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

351627:CSAC RS07510
gene id: 351627:CSAC_RS07510
uniprot id: A4XJJ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS03400
gene id: 351627:CSAC_RS03400
uniprot id: A4XHA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351627:CSAC RS06645
gene id: 351627:CSAC_RS06645
uniprot id: A4XJ30
names: Similarity
messages: Belongs to the UPF0237 family.

351627:CSAC RS00615
gene id: 351627:CSAC_RS00615
uniprot id: A4XFU2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS13720
gene id: 351627:CSAC_RS13720
uniprot id: A4XMZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CotF family.
messages: Spore coat

351627:CSAC RS06340
gene id: 351627:CSAC_RS06340
uniprot id: A4XIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

351627:CSAC RS08810
gene id: 351627:CSAC_RS08810
uniprot id: A4XK96
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

351627:CSAC RS08620
gene id: 351627:CSAC_RS08620
uniprot id: A4XK57
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

351627:CSAC RS09020
gene id: 351627:CSAC_RS09020
uniprot id: A4XKD4
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351627:CSAC RS08750
gene id: 351627:CSAC_RS08750
uniprot id: A4XK84
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

351627:CSAC RS13905
gene id: 351627:CSAC_RS13905
uniprot id: A4XN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS08850
gene id: 351627:CSAC_RS08850
uniprot id: A4XKA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

351627:CSAC RS10420
gene id: 351627:CSAC_RS10420
uniprot id: A4XL64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

351627:CSAC RS09885
gene id: 351627:CSAC_RS09885
uniprot id: A4XKV7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

351627:CSAC RS02030
gene id: 351627:CSAC_RS02030
uniprot id: A4XGK8
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS09635
gene id: 351627:CSAC_RS09635
uniprot id: A4XKQ7
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

351627:CSAC RS08225
gene id: 351627:CSAC_RS08225
uniprot id: A4XJY0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

351627:CSAC RS01510
gene id: 351627:CSAC_RS01510
uniprot id: A4XGA7
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

351627:CSAC RS00885
gene id: 351627:CSAC_RS00885
uniprot id: A4XFY9
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

351627:CSAC RS06685
gene id: 351627:CSAC_RS06685
uniprot id: A4XJ38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

351627:CSAC RS01045
gene id: 351627:CSAC_RS01045
uniprot id: A4XG19
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

351627:CSAC RS00575
gene id: 351627:CSAC_RS00575
uniprot id: A4XFT4
names: Similarity
messages: Belongs to the PspA/IM30 family.

351627:CSAC RS04435
gene id: 351627:CSAC_RS04435
uniprot id: A4XHV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

351627:CSAC RS01820
gene id: 351627:CSAC_RS01820
uniprot id: A4XGG8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

351627:CSAC RS02565
gene id: 351627:CSAC_RS02565
uniprot id: A4XGW0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS09060
gene id: 351627:CSAC_RS09060
uniprot id: A4XKE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

351627:CSAC RS08390
gene id: 351627:CSAC_RS08390
uniprot id: A4XK12
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

351627:CSAC RS09170
gene id: 351627:CSAC_RS09170
uniprot id: A4XKG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

351627:CSAC RS08890
gene id: 351627:CSAC_RS08890
uniprot id: A4XKB1
names: Similarity
messages: Belongs to the peptidase M29 family.

351627:CSAC RS11845
gene id: 351627:CSAC_RS11845
uniprot id: A4XLY4
names: Similarity
messages: Belongs to the peptidase S41A family.

351627:CSAC RS13970
gene id: 351627:CSAC_RS13970
uniprot id: A4XMN2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351627:CSAC RS01230
gene id: 351627:CSAC_RS01230
uniprot id: A4XG56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

351627:CSAC RS06765
gene id: 351627:CSAC_RS06765
uniprot id: A4XJ54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

351627:CSAC RS11475
gene id: 351627:CSAC_RS11475
uniprot id: A4XLR0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

351627:CSAC RS08130
gene id: 351627:CSAC_RS08130
uniprot id: A4XJW3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

351627:CSAC RS03755
gene id: 351627:CSAC_RS03755
uniprot id: A4XHH9
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

351627:CSAC RS07680
gene id: 351627:CSAC_RS07680
uniprot id: A4XJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease PrsW family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS04745
gene id: 351627:CSAC_RS04745
uniprot id: A4XI14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

351627:CSAC RS06425
gene id: 351627:CSAC_RS06425
uniprot id: A4XIY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

351627:CSAC RS09855
gene id: 351627:CSAC_RS09855
uniprot id: A4XKV1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

351627:CSAC RS09675
gene id: 351627:CSAC_RS09675
uniprot id: A4XKR5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

351627:CSAC RS03570
gene id: 351627:CSAC_RS03570
uniprot id: A4XHE1
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

351627:CSAC RS07685
gene id: 351627:CSAC_RS07685
uniprot id: A4XJM5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS09790
gene id: 351627:CSAC_RS09790
uniprot id: A4XKT8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

351627:CSAC RS07045
gene id: 351627:CSAC_RS07045
uniprot id: A4XJB0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

351627:CSAC RS04815
gene id: 351627:CSAC_RS04815
uniprot id: A4XI28
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

351627:CSAC RS13775
gene id: 351627:CSAC_RS13775
uniprot id: A4XMZ7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

351627:CSAC RS10365
gene id: 351627:CSAC_RS10365
uniprot id: A4XL53
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

351627:CSAC RS11855
gene id: 351627:CSAC_RS11855
uniprot id: A4XLY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

351627:CSAC RS06395
gene id: 351627:CSAC_RS06395
uniprot id: A4XIY2
names: Similarity
messages: Belongs to the FlgD family.

351627:CSAC RS09455
gene id: 351627:CSAC_RS09455
uniprot id: A4XKM1
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

351627:CSAC RS02700
gene id: 351627:CSAC_RS02700
uniprot id: A4XGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

351627:CSAC RS11525
gene id: 351627:CSAC_RS11525
uniprot id: A4XLS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

351627:CSAC RS10475
gene id: 351627:CSAC_RS10475
uniprot id: A4XL75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

351627:CSAC RS08370
gene id: 351627:CSAC_RS08370
uniprot id: A4XK09
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

351627:CSAC RS03965
gene id: 351627:CSAC_RS03965
uniprot id: A4XHM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351627:CSAC RS08650
gene id: 351627:CSAC_RS08650
uniprot id: A4XK63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS05955
gene id: 351627:CSAC_RS05955
uniprot id: A4XFM2
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

351627:CSAC RS10805
gene id: 351627:CSAC_RS10805
uniprot id: A4XLE1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

351627:CSAC RS04130
gene id: 351627:CSAC_RS04130
uniprot id: A4XHQ0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

351627:CSAC RS12830
gene id: 351627:CSAC_RS12830
uniprot id: A4XMH7
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

351627:CSAC RS10610
gene id: 351627:CSAC_RS10610
uniprot id: A4XFN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

351627:CSAC RS09295
gene id: 351627:CSAC_RS09295
uniprot id: A4XKI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

351627:CSAC RS01065
gene id: 351627:CSAC_RS01065
uniprot id: A4XG23
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

351627:CSAC RS11540
gene id: 351627:CSAC_RS11540
uniprot id: A4XLS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

351627:CSAC RS06495
gene id: 351627:CSAC_RS06495
uniprot id: A4XJ01
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

351627:CSAC RS13835
gene id: 351627:CSAC_RS13835
uniprot id: A4XN08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351627:CSAC RS12270
gene id: 351627:CSAC_RS12270
uniprot id: A4XM69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

351627:CSAC RS08070
gene id: 351627:CSAC_RS08070
uniprot id: A4XJV1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

351627:CSAC RS04855
gene id: 351627:CSAC_RS04855
uniprot id: A4XI36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

351627:CSAC RS09955
gene id: 351627:CSAC_RS09955
uniprot id: A4XKX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

351627:CSAC RS09720
gene id: 351627:CSAC_RS09720
uniprot id: A4XKS4
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Purine nucleoside phosphorylase involved in purine salvage.

351627:CSAC RS12185
gene id: 351627:CSAC_RS12185
uniprot id: A4XM52
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

351627:CSAC RS01910
gene id: 351627:CSAC_RS01910
uniprot id: A4XGI6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

351627:CSAC RS07905
gene id: 351627:CSAC_RS07905
uniprot id: A4XJR9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.
messages: Homotetramer.

351627:CSAC RS02145
gene id: 351627:CSAC_RS02145
uniprot id: A4XGN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

351627:CSAC RS12535
gene id: 351627:CSAC_RS12535
uniprot id: A4XMC2
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

351627:CSAC RS08360
gene id: 351627:CSAC_RS08360
uniprot id: A4XK07
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

351627:CSAC RS01755
gene id: 351627:CSAC_RS01755
uniprot id: A4XGF5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

351627:CSAC RS13915
gene id: 351627:CSAC_RS13915
uniprot id: A4XN23
names: Similarity
messages: Belongs to the DapA family.

351627:CSAC RS02050
gene id: 351627:CSAC_RS02050
uniprot id: A4XGL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

351627:CSAC RS10470
gene id: 351627:CSAC_RS10470
uniprot id: A4XL74
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

351627:CSAC RS00765
gene id: 351627:CSAC_RS00765
uniprot id: A4XFX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

351627:CSAC RS12455
gene id: 351627:CSAC_RS12455
uniprot id: A4XMA6
names: Similarity
messages: Belongs to the P(II) protein family.

351627:CSAC RS02330
gene id: 351627:CSAC_RS02330
uniprot id: A4XGR4
names: Similarity
messages: Belongs to the hemerythrin family.

351627:CSAC RS06065
gene id: 351627:CSAC_RS06065
uniprot id: A4XIS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

351627:CSAC RS11115
gene id: 351627:CSAC_RS11115
uniprot id: A4XLJ7
names: Subcellular Location Annotation
messages: Membrane

351627:CSAC RS12500
gene id: 351627:CSAC_RS12500
uniprot id: A4XMB5
names: Subcellular Location Annotation
messages: Membrane