351607:ACEL RS05525
gene id: 351607:ACEL_RS05525
uniprot id: A0LTT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

351607:ACEL RS01880
gene id: 351607:ACEL_RS01880
uniprot id: A0LRS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

351607:ACEL RS10450
gene id: 351607:ACEL_RS10450
uniprot id: A0LWI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

351607:ACEL RS07565
gene id: 351607:ACEL_RS07565
uniprot id: A0LUY1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

351607:ACEL RS07985
gene id: 351607:ACEL_RS07985
uniprot id: A0LV62
names: Similarity
messages: Belongs to the UPF0102 family.

351607:ACEL RS06305
gene id: 351607:ACEL_RS06305
uniprot id: A0LU89
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

351607:ACEL RS04515
gene id: 351607:ACEL_RS04515
uniprot id: A0LT86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

351607:ACEL RS02675
gene id: 351607:ACEL_RS02675
uniprot id: A0LS82
names: Similarity
messages: Belongs to the universal stress protein A family.

351607:ACEL RS08900
gene id: 351607:ACEL_RS08900
uniprot id: A0LVP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

351607:ACEL RS05070
gene id: 351607:ACEL_RS05070
uniprot id: A0LTJ7
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

351607:ACEL RS02410
gene id: 351607:ACEL_RS02410
uniprot id: A0LS29
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351607:ACEL RS10120
gene id: 351607:ACEL_RS10120
uniprot id: A0LWC1
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS03380
gene id: 351607:ACEL_RS03380
uniprot id: A0LSL9
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

351607:ACEL RS01615
gene id: 351607:ACEL_RS01615
uniprot id: A0LRM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

351607:ACEL RS02035
gene id: 351607:ACEL_RS02035
uniprot id: A0LRV8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

351607:ACEL RS07770
gene id: 351607:ACEL_RS07770
uniprot id: A0LV19
names: Similarity
messages: Belongs to the peptidase M16 family.

351607:ACEL RS05180
gene id: 351607:ACEL_RS05180
uniprot id: A0LTL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

351607:ACEL RS03500
gene id: 351607:ACEL_RS03500
uniprot id: A0LSP3
names: Function
names: Similarity
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

351607:ACEL RS04300
gene id: 351607:ACEL_RS04300
uniprot id: A0LT44
names: Similarity
messages: Belongs to the bacterial flagellin family.

351607:ACEL RS01690
gene id: 351607:ACEL_RS01690
uniprot id: A0LRN8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

351607:ACEL RS00005
gene id: 351607:ACEL_RS00005
uniprot id: A0LQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

351607:ACEL RS08185
gene id: 351607:ACEL_RS08185
uniprot id: A0LVA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

351607:ACEL RS06105
gene id: 351607:ACEL_RS06105
uniprot id: A0LU49
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

351607:ACEL RS03755
gene id: 351607:ACEL_RS03755
uniprot id: A0LSU2
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04040
gene id: 351607:ACEL_RS04040
uniprot id: A0LSZ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

351607:ACEL RS07775
gene id: 351607:ACEL_RS07775
uniprot id: A0LV20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

351607:ACEL RS01115
gene id: 351607:ACEL_RS01115
uniprot id: A0LRC6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

351607:ACEL RS00940
gene id: 351607:ACEL_RS00940
uniprot id: A0LR93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

351607:ACEL RS10100
gene id: 351607:ACEL_RS10100
uniprot id: A0LWB7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS05765
gene id: 351607:ACEL_RS05765
uniprot id: A0LTY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351607:ACEL RS06835
gene id: 351607:ACEL_RS06835
uniprot id: A0LUJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

351607:ACEL RS08180
gene id: 351607:ACEL_RS08180
uniprot id: A0LVA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

351607:ACEL RS07630
gene id: 351607:ACEL_RS07630
uniprot id: A0LUZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

351607:ACEL RS06505
gene id: 351607:ACEL_RS06505
uniprot id: A0LUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

351607:ACEL RS03305
gene id: 351607:ACEL_RS03305
uniprot id: A0LSK5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

351607:ACEL RS11170
gene id: 351607:ACEL_RS11170
uniprot id: A0LWW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

351607:ACEL RS09485
gene id: 351607:ACEL_RS09485
uniprot id: A0LVZ8
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

351607:ACEL RS03845
gene id: 351607:ACEL_RS03845
uniprot id: A0LSW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

351607:ACEL RS06680
gene id: 351607:ACEL_RS06680
uniprot id: A0LUG0
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS02580
gene id: 351607:ACEL_RS02580
uniprot id: A0LS62
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

351607:ACEL RS08530
gene id: 351607:ACEL_RS08530
uniprot id: A0LVG6
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01445
gene id: 351607:ACEL_RS01445
uniprot id: A0LRJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

351607:ACEL RS04150
gene id: 351607:ACEL_RS04150
uniprot id: A0LT19
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

351607:ACEL RS01135
gene id: 351607:ACEL_RS01135
uniprot id: A0LRD0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS01335
gene id: 351607:ACEL_RS01335
uniprot id: A0LRH1
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS08065
gene id: 351607:ACEL_RS08065
uniprot id: A0LV78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS12190
gene id: 351607:ACEL_RS12190
uniprot id: A0LR61
names: Similarity
messages: Belongs to the neocarzinostatin family.

351607:ACEL RS04090
gene id: 351607:ACEL_RS04090
uniprot id: A0LT07
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS01000
gene id: 351607:ACEL_RS01000
uniprot id: A0LRA3
names: Similarity
messages: Belongs to the EfeM/EfeO family.

351607:ACEL RS09000
gene id: 351607:ACEL_RS09000
uniprot id: A0LVQ6
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

351607:ACEL RS05045
gene id: 351607:ACEL_RS05045
uniprot id: A0LTJ2
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

351607:ACEL RS01415
gene id: 351607:ACEL_RS01415
uniprot id: A0LRI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS04505
gene id: 351607:ACEL_RS04505
uniprot id: A0LT84
names: Similarity
messages: Belongs to the ribulokinase family.

351607:ACEL RS01050
gene id: 351607:ACEL_RS01050
uniprot id: A0LRB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

351607:ACEL RS04525
gene id: 351607:ACEL_RS04525
uniprot id: A0LT88
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

351607:ACEL RS01570
gene id: 351607:ACEL_RS01570
uniprot id: A0LRL4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351607:ACEL RS06865
gene id: 351607:ACEL_RS06865
uniprot id: A0LUJ7
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

351607:ACEL RS11205
gene id: 351607:ACEL_RS11205
uniprot id: A0LWX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

351607:ACEL RS05810
gene id: 351607:ACEL_RS05810
uniprot id: A0LTZ2
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00330
gene id: 351607:ACEL_RS00330
uniprot id: A0LQX7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

351607:ACEL RS04965
gene id: 351607:ACEL_RS04965
uniprot id: A0LTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Cell membrane
messages: Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.

351607:ACEL RS03110
gene id: 351607:ACEL_RS03110
uniprot id: A0LSH1
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

351607:ACEL RS05800
gene id: 351607:ACEL_RS05800
uniprot id: A0LTZ0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

351607:ACEL RS08035
gene id: 351607:ACEL_RS08035
uniprot id: A0LV72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

351607:ACEL RS11050
gene id: 351607:ACEL_RS11050
uniprot id: A0LWU1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

351607:ACEL RS04895
gene id: 351607:ACEL_RS04895
uniprot id: A0LTG1
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

351607:ACEL RS00690
gene id: 351607:ACEL_RS00690
uniprot id: A0LR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS04860
gene id: 351607:ACEL_RS04860
uniprot id: A0LTF4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

351607:ACEL RS08515
gene id: 351607:ACEL_RS08515
uniprot id: A0LVG3
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01390
gene id: 351607:ACEL_RS01390
uniprot id: A0LRI2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS08800
gene id: 351607:ACEL_RS08800
uniprot id: A0LVL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

351607:ACEL RS02965
gene id: 351607:ACEL_RS02965
uniprot id: A0LSE2
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01980
gene id: 351607:ACEL_RS01980
uniprot id: A0LRU7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

351607:ACEL RS00525
gene id: 351607:ACEL_RS00525
uniprot id: A0LR15
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

351607:ACEL RS08385
gene id: 351607:ACEL_RS08385
uniprot id: A0LVD9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS11095
gene id: 351607:ACEL_RS11095
uniprot id: A0LWV0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

351607:ACEL RS11450
gene id: 351607:ACEL_RS11450
uniprot id: A0LTI4
names: Similarity
messages: Belongs to the peptidase C40 family.

351607:ACEL RS11265
gene id: 351607:ACEL_RS11265
uniprot id: A0LR57
names: Similarity
messages: Belongs to the neocarzinostatin family.

351607:ACEL RS05805
gene id: 351607:ACEL_RS05805
uniprot id: A0LTZ1
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

351607:ACEL RS11135
gene id: 351607:ACEL_RS11135
uniprot id: A0LWV8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351607:ACEL RS04695
gene id: 351607:ACEL_RS04695
uniprot id: A0LTC1
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS05640
gene id: 351607:ACEL_RS05640
uniprot id: A0LTV8
names: Similarity
messages: Belongs to the glutamine synthetase family.

351607:ACEL RS03350
gene id: 351607:ACEL_RS03350
uniprot id: A0LSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

351607:ACEL RS04420
gene id: 351607:ACEL_RS04420
uniprot id: A0LT67
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

351607:ACEL RS10395
gene id: 351607:ACEL_RS10395
uniprot id: A0LWH4
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

351607:ACEL RS06860
gene id: 351607:ACEL_RS06860
uniprot id: A0LUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS02120
gene id: 351607:ACEL_RS02120
uniprot id: A0LRX4
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

351607:ACEL RS04405
gene id: 351607:ACEL_RS04405
uniprot id: A0LT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

351607:ACEL RS06390
gene id: 351607:ACEL_RS06390
uniprot id: A0LUA5
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

351607:ACEL RS01620
gene id: 351607:ACEL_RS01620
uniprot id: A0LRM4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

351607:ACEL RS03890
gene id: 351607:ACEL_RS03890
uniprot id: A0LSW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

351607:ACEL RS11045
gene id: 351607:ACEL_RS11045
uniprot id: A0LWU0
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

351607:ACEL RS06065
gene id: 351607:ACEL_RS06065
uniprot id: A0LU41
names: Similarity
messages: Belongs to the ABC transporter superfamily.

351607:ACEL RS03285
gene id: 351607:ACEL_RS03285
uniprot id: A0LSK1
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

351607:ACEL RS06190
gene id: 351607:ACEL_RS06190
uniprot id: A0LU67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

351607:ACEL RS07160
gene id: 351607:ACEL_RS07160
uniprot id: A0LUQ1
names: Similarity
messages: Belongs to the peptidase S8 family.

351607:ACEL RS03580
gene id: 351607:ACEL_RS03580
uniprot id: A0LSQ9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

351607:ACEL RS09595
gene id: 351607:ACEL_RS09595
uniprot id: A0LW20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

351607:ACEL RS01605
gene id: 351607:ACEL_RS01605
uniprot id: A0LRM1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

351607:ACEL RS01735
gene id: 351607:ACEL_RS01735
uniprot id: A0LRP8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

351607:ACEL RS01200
gene id: 351607:ACEL_RS01200
uniprot id: A0LRE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

351607:ACEL RS09700
gene id: 351607:ACEL_RS09700
uniprot id: A0LW41
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

351607:ACEL RS05065
gene id: 351607:ACEL_RS05065
uniprot id: A0LTJ6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

351607:ACEL RS11070
gene id: 351607:ACEL_RS11070
uniprot id: A0LWU5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

351607:ACEL RS01210
gene id: 351607:ACEL_RS01210
uniprot id: A0LRE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS05530
gene id: 351607:ACEL_RS05530
uniprot id: A0LTT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

351607:ACEL RS10460
gene id: 351607:ACEL_RS10460
uniprot id: A0LWI4
names: Similarity
messages: Belongs to the AlaDH/PNT family.

351607:ACEL RS08260
gene id: 351607:ACEL_RS08260
uniprot id: A0LVB6
names: Similarity
messages: Belongs to the peptidase S9A family.

351607:ACEL RS10040
gene id: 351607:ACEL_RS10040
uniprot id: A0LWA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

351607:ACEL RS04395
gene id: 351607:ACEL_RS04395
uniprot id: A0LT62
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

351607:ACEL RS03330
gene id: 351607:ACEL_RS03330
uniprot id: A0LSL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

351607:ACEL RS07810
gene id: 351607:ACEL_RS07810
uniprot id: A0LV27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

351607:ACEL RS05790
gene id: 351607:ACEL_RS05790
uniprot id: A0LTY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

351607:ACEL RS05125
gene id: 351607:ACEL_RS05125
uniprot id: A0LTK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

351607:ACEL RS03065
gene id: 351607:ACEL_RS03065
uniprot id: A0LSG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

351607:ACEL RS00170
gene id: 351607:ACEL_RS00170
uniprot id: A0LQU7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

351607:ACEL RS05330
gene id: 351607:ACEL_RS05330
uniprot id: A0LTP7
names: Similarity
messages: Belongs to the UPF0047 family.

351607:ACEL RS08295
gene id: 351607:ACEL_RS08295
uniprot id: A0LVC1
names: Similarity
messages: Belongs to the truncated hemoglobin family. Group II subfamily.

351607:ACEL RS03650
gene id: 351607:ACEL_RS03650
uniprot id: A0LSS3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS02245
gene id: 351607:ACEL_RS02245
uniprot id: A0LRZ7
names: Similarity
messages: Belongs to the IlvD/Edd family.

351607:ACEL RS06615
gene id: 351607:ACEL_RS06615
uniprot id: A0LUE7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351607:ACEL RS01700
gene id: 351607:ACEL_RS01700
uniprot id: A0LRP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

351607:ACEL RS07730
gene id: 351607:ACEL_RS07730
uniprot id: A0LV11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

351607:ACEL RS04340
gene id: 351607:ACEL_RS04340
uniprot id: A0LT52
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

351607:ACEL RS01970
gene id: 351607:ACEL_RS01970
uniprot id: A0LRU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

351607:ACEL RS06275
gene id: 351607:ACEL_RS06275
uniprot id: A0LU83
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00435
gene id: 351607:ACEL_RS00435
uniprot id: A0LQZ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS10600
gene id: 351607:ACEL_RS10600
uniprot id: A0LWL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

351607:ACEL RS07765
gene id: 351607:ACEL_RS07765
uniprot id: A0LV18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

351607:ACEL RS03645
gene id: 351607:ACEL_RS03645
uniprot id: A0LSS2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

351607:ACEL RS02500
gene id: 351607:ACEL_RS02500
uniprot id: A0LS46
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS07005
gene id: 351607:ACEL_RS07005
uniprot id: A0LUM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS03840
gene id: 351607:ACEL_RS03840
uniprot id: A0LSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS06790
gene id: 351607:ACEL_RS06790
uniprot id: A0LUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS02690
gene id: 351607:ACEL_RS02690
uniprot id: A0LS85
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

351607:ACEL RS12355
gene id: 351607:ACEL_RS12355
uniprot id: A0LUK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

351607:ACEL RS06465
gene id: 351607:ACEL_RS06465
uniprot id: A0LUB7
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

351607:ACEL RS05660
gene id: 351607:ACEL_RS05660
uniprot id: A0LTW2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351607:ACEL RS04825
gene id: 351607:ACEL_RS04825
uniprot id: A0LTE7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

351607:ACEL RS01765
gene id: 351607:ACEL_RS01765
uniprot id: A0LRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS02150
gene id: 351607:ACEL_RS02150
uniprot id: A0LRY0
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

351607:ACEL RS06650
gene id: 351607:ACEL_RS06650
uniprot id: A0LUF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

351607:ACEL RS08130
gene id: 351607:ACEL_RS08130
uniprot id: A0LV92
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

351607:ACEL RS09855
gene id: 351607:ACEL_RS09855
uniprot id: A0LW71
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

351607:ACEL RS05695
gene id: 351607:ACEL_RS05695
uniprot id: A0LTW9
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase Eis family.
messages: Homohexamer; trimer of dimers.

351607:ACEL RS09585
gene id: 351607:ACEL_RS09585
uniprot id: A0LW18
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

351607:ACEL RS06030
gene id: 351607:ACEL_RS06030
uniprot id: A0LU34
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
messages: Monomer.

351607:ACEL RS10815
gene id: 351607:ACEL_RS10815
uniprot id: A0LWQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS07265
gene id: 351607:ACEL_RS07265
uniprot id: A0LUS2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351607:ACEL RS01610
gene id: 351607:ACEL_RS01610
uniprot id: A0LRM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

351607:ACEL RS08055
gene id: 351607:ACEL_RS08055
uniprot id: A0LV76
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

351607:ACEL RS08230
gene id: 351607:ACEL_RS08230
uniprot id: A0LVB0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

351607:ACEL RS06090
gene id: 351607:ACEL_RS06090
uniprot id: A0LU46
names: Domain
names: Function
names: Similarity
names: Subunit
messages: ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
messages: Belongs to the AAA ATPase family.
messages: Consists of three main regions, an N-terminal coiled-coil domain that binds to protein Pup and functions as a docking station, an interdomain involved in ARC hexamerization, and a C-terminal ATPase domain of the AAA type.
messages: Homohexamer. Assembles into a hexameric ring structure that caps the 20S proteasome core. Strongly interacts with the prokaryotic ubiquitin-like protein Pup through a hydrophobic interface; the interacting region of ARC lies in its N-terminal coiled-coil domain. There is one Pup binding site per ARC hexamer ring. Upon ATP-binding, the C-terminus of ARC interacts with the alpha-rings of the proteasome core, possibly by binding to the intersubunit pockets.

351607:ACEL RS08915
gene id: 351607:ACEL_RS08915
uniprot id: A0LVP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

351607:ACEL RS06625
gene id: 351607:ACEL_RS06625
uniprot id: A0LUE9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351607:ACEL RS08320
gene id: 351607:ACEL_RS08320
uniprot id: A0LVC6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

351607:ACEL RS01480
gene id: 351607:ACEL_RS01480
uniprot id: A0LRK0
names: Similarity
messages: Belongs to the UPF0234 family.

351607:ACEL RS06410
gene id: 351607:ACEL_RS06410
uniprot id: A0LUA9
names: Similarity
messages: Belongs to the TlyA family.

351607:ACEL RS06725
gene id: 351607:ACEL_RS06725
uniprot id: A0LUG9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01715
gene id: 351607:ACEL_RS01715
uniprot id: A0LRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

351607:ACEL RS00305
gene id: 351607:ACEL_RS00305
uniprot id: A0LQX3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351607:ACEL RS06545
gene id: 351607:ACEL_RS06545
uniprot id: A0LUD3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

351607:ACEL RS09275
gene id: 351607:ACEL_RS09275
uniprot id: A0LVV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS09685
gene id: 351607:ACEL_RS09685
uniprot id: A0LW38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

351607:ACEL RS01665
gene id: 351607:ACEL_RS01665
uniprot id: A0LRN3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

351607:ACEL RS05345
gene id: 351607:ACEL_RS05345
uniprot id: A0LTQ1
names: Similarity
messages: Belongs to the cytochrome P450 family.

351607:ACEL RS05900
gene id: 351607:ACEL_RS05900
uniprot id: A0LU10
names: Similarity
messages: Belongs to the peptidase U62 family.

351607:ACEL RS02180
gene id: 351607:ACEL_RS02180
uniprot id: A0LRY5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

351607:ACEL RS04745
gene id: 351607:ACEL_RS04745
uniprot id: A0LTD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS09745
gene id: 351607:ACEL_RS09745
uniprot id: A0LW50
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

351607:ACEL RS08350
gene id: 351607:ACEL_RS08350
uniprot id: A0LVD2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS07920
gene id: 351607:ACEL_RS07920
uniprot id: A0LV49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS08245
gene id: 351607:ACEL_RS08245
uniprot id: A0LVB3
names: Similarity
messages: Belongs to the disproportionating enzyme family.

351607:ACEL RS04840
gene id: 351607:ACEL_RS04840
uniprot id: A0LTF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

351607:ACEL RS05185
gene id: 351607:ACEL_RS05185
uniprot id: A0LTM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

351607:ACEL RS04830
gene id: 351607:ACEL_RS04830
uniprot id: A0LTE8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

351607:ACEL RS11715
gene id: 351607:ACEL_RS11715
uniprot id: A0LWE8
names: Similarity
messages: Belongs to the SCO1/2 family.

351607:ACEL RS06735
gene id: 351607:ACEL_RS06735
uniprot id: A0LUH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

351607:ACEL RS10820
gene id: 351607:ACEL_RS10820
uniprot id: A0LWQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS07745
gene id: 351607:ACEL_RS07745
uniprot id: A0LV14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

351607:ACEL RS10960
gene id: 351607:ACEL_RS10960
uniprot id: A0LWS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
messages: Homotrimer.

351607:ACEL RS06690
gene id: 351607:ACEL_RS06690
uniprot id: A0LUG2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

351607:ACEL RS03335
gene id: 351607:ACEL_RS03335
uniprot id: A0LSL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

351607:ACEL RS06110
gene id: 351607:ACEL_RS06110
uniprot id: A0LU50
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

351607:ACEL RS04655
gene id: 351607:ACEL_RS04655
uniprot id: A0LTB3
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

351607:ACEL RS01505
gene id: 351607:ACEL_RS01505
uniprot id: A0LRK2
names: Similarity
messages: Belongs to the UPF0336 family.

351607:ACEL RS10420
gene id: 351607:ACEL_RS10420
uniprot id: A0LWH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

351607:ACEL RS10825
gene id: 351607:ACEL_RS10825
uniprot id: A0LWQ2
names: Similarity
messages: Belongs to the GSP E family.

351607:ACEL RS04750
gene id: 351607:ACEL_RS04750
uniprot id: A0LTD2
names: Similarity
messages: Belongs to the glutamine synthetase family.

351607:ACEL RS00835
gene id: 351607:ACEL_RS00835
uniprot id: A0LR73
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase involved in purine salvage.

351607:ACEL RS04850
gene id: 351607:ACEL_RS04850
uniprot id: A0LTF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

351607:ACEL RS02610
gene id: 351607:ACEL_RS02610
uniprot id: A0LS68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

351607:ACEL RS10490
gene id: 351607:ACEL_RS10490
uniprot id: A0LWJ0
names: Similarity
messages: Belongs to the PhoU family.
messages: Belongs to the UPF0111 family.

351607:ACEL RS10355
gene id: 351607:ACEL_RS10355
uniprot id: A0LWG8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

351607:ACEL RS07720
gene id: 351607:ACEL_RS07720
uniprot id: A0LV09
names: Similarity
messages: Belongs to the CinA family.

351607:ACEL RS12235
gene id: 351607:ACEL_RS12235
uniprot id: A0LSJ9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351607:ACEL RS06060
gene id: 351607:ACEL_RS06060
uniprot id: A0LU40
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS09795
gene id: 351607:ACEL_RS09795
uniprot id: A0LW60
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

351607:ACEL RS06630
gene id: 351607:ACEL_RS06630
uniprot id: A0LUF0
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: Catalyzes the reversible reductive amination of pyruvate to L-alanine.

351607:ACEL RS10710
gene id: 351607:ACEL_RS10710
uniprot id: A0LWM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

351607:ACEL RS02095
gene id: 351607:ACEL_RS02095
uniprot id: A0LRW9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

351607:ACEL RS05845
gene id: 351607:ACEL_RS05845
uniprot id: A0LTZ9
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

351607:ACEL RS09965
gene id: 351607:ACEL_RS09965
uniprot id: A0LW92
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS08145
gene id: 351607:ACEL_RS08145
uniprot id: A0LV95
names: Function
messages: Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.

351607:ACEL RS10070
gene id: 351607:ACEL_RS10070
uniprot id: A0LWB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

351607:ACEL RS05535
gene id: 351607:ACEL_RS05535
uniprot id: A0LTT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

351607:ACEL RS02755
gene id: 351607:ACEL_RS02755
uniprot id: A0LS98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS01990
gene id: 351607:ACEL_RS01990
uniprot id: A0LRU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

351607:ACEL RS07800
gene id: 351607:ACEL_RS07800
uniprot id: A0LV25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

351607:ACEL RS07825
gene id: 351607:ACEL_RS07825
uniprot id: A0LV30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

351607:ACEL RS08380
gene id: 351607:ACEL_RS08380
uniprot id: A0LVD8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

351607:ACEL RS04740
gene id: 351607:ACEL_RS04740
uniprot id: A0LTD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

351607:ACEL RS03455
gene id: 351607:ACEL_RS03455
uniprot id: A0LSN5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

351607:ACEL RS10695
gene id: 351607:ACEL_RS10695
uniprot id: A0LWM5
names: Similarity
messages: Belongs to the MT-A70-like family.

351607:ACEL RS02935
gene id: 351607:ACEL_RS02935
uniprot id: A0LSD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

351607:ACEL RS00875
gene id: 351607:ACEL_RS00875
uniprot id: A0LR81
names: Similarity
messages: Belongs to the UDPGP type 2 family.

351607:ACEL RS04070
gene id: 351607:ACEL_RS04070
uniprot id: A0LT03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

351607:ACEL RS10015
gene id: 351607:ACEL_RS10015
uniprot id: A0LWA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

351607:ACEL RS07820
gene id: 351607:ACEL_RS07820
uniprot id: A0LV29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

351607:ACEL RS11055
gene id: 351607:ACEL_RS11055
uniprot id: A0LWU2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

351607:ACEL RS03140
gene id: 351607:ACEL_RS03140
uniprot id: P54583
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
messages: Has a very high specific activity on carboxymethylcellulose.

351607:ACEL RS07830
gene id: 351607:ACEL_RS07830
uniprot id: A0LV31
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS09090
gene id: 351607:ACEL_RS09090
uniprot id: A0LVS1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

351607:ACEL RS10705
gene id: 351607:ACEL_RS10705
uniprot id: A0LWM7
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

351607:ACEL RS07195
gene id: 351607:ACEL_RS07195
uniprot id: A0LUQ8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

351607:ACEL RS09525
gene id: 351607:ACEL_RS09525
uniprot id: A0LW06
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

351607:ACEL RS06500
gene id: 351607:ACEL_RS06500
uniprot id: A0LUC4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

351607:ACEL RS08660
gene id: 351607:ACEL_RS08660
uniprot id: A0LVJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

351607:ACEL RS02255
gene id: 351607:ACEL_RS02255
uniprot id: A0LRZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS01520
gene id: 351607:ACEL_RS01520
uniprot id: A0LRK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

351607:ACEL RS03365
gene id: 351607:ACEL_RS03365
uniprot id: A0LSL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

351607:ACEL RS01590
gene id: 351607:ACEL_RS01590
uniprot id: A0LRL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

351607:ACEL RS09680
gene id: 351607:ACEL_RS09680
uniprot id: A0LW37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

351607:ACEL RS01385
gene id: 351607:ACEL_RS01385
uniprot id: A0LRI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS03820
gene id: 351607:ACEL_RS03820
uniprot id: A0LSV5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

351607:ACEL RS03020
gene id: 351607:ACEL_RS03020
uniprot id: A0LSF3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

351607:ACEL RS10415
gene id: 351607:ACEL_RS10415
uniprot id: A0LWH7
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

351607:ACEL RS07665
gene id: 351607:ACEL_RS07665
uniprot id: A0LV01
names: Similarity
messages: Belongs to the peptidase S9C family.

351607:ACEL RS00495
gene id: 351607:ACEL_RS00495
uniprot id: A0LR09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

351607:ACEL RS00480
gene id: 351607:ACEL_RS00480
uniprot id: A0LR06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

351607:ACEL RS06495
gene id: 351607:ACEL_RS06495
uniprot id: A0LUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

351607:ACEL RS04085
gene id: 351607:ACEL_RS04085
uniprot id: A0LT06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS10890
gene id: 351607:ACEL_RS10890
uniprot id: A0LWR4
names: Similarity
names: Subunit
messages: Belongs to the Bpa family.
messages: Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings.

351607:ACEL RS00580
gene id: 351607:ACEL_RS00580
uniprot id: A0LR26
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10105
gene id: 351607:ACEL_RS10105
uniprot id: A0LWB8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

351607:ACEL RS08910
gene id: 351607:ACEL_RS08910
uniprot id: A0LVP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

351607:ACEL RS06840
gene id: 351607:ACEL_RS06840
uniprot id: A0LUJ2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

351607:ACEL RS03900
gene id: 351607:ACEL_RS03900
uniprot id: A0LSX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS09760
gene id: 351607:ACEL_RS09760
uniprot id: A0LW53
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351607:ACEL RS08020
gene id: 351607:ACEL_RS08020
uniprot id: A0LV69
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

351607:ACEL RS01430
gene id: 351607:ACEL_RS01430
uniprot id: A0LRJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS06400
gene id: 351607:ACEL_RS06400
uniprot id: A0LUA7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

351607:ACEL RS01655
gene id: 351607:ACEL_RS01655
uniprot id: A0LRN1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

351607:ACEL RS10625
gene id: 351607:ACEL_RS10625
uniprot id: A0LWL7
names: Function
messages: Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.

351607:ACEL RS11065
gene id: 351607:ACEL_RS11065
uniprot id: A0LWU4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01205
gene id: 351607:ACEL_RS01205
uniprot id: A0LRE4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

351607:ACEL RS04855
gene id: 351607:ACEL_RS04855
uniprot id: A0LTF3
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

351607:ACEL RS10975
gene id: 351607:ACEL_RS10975
uniprot id: A0LWS7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

351607:ACEL RS05245
gene id: 351607:ACEL_RS05245
uniprot id: A0LTN2
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

351607:ACEL RS03635
gene id: 351607:ACEL_RS03635
uniprot id: A0LSS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

351607:ACEL RS01650
gene id: 351607:ACEL_RS01650
uniprot id: A0LRN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

351607:ACEL RS09340
gene id: 351607:ACEL_RS09340
uniprot id: A0LVW9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04975
gene id: 351607:ACEL_RS04975
uniprot id: A0LTH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS01410
gene id: 351607:ACEL_RS01410
uniprot id: A0LRI6
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

351607:ACEL RS07260
gene id: 351607:ACEL_RS07260
uniprot id: A0LUS1
names: Similarity
messages: Belongs to the peptidase S8 family.

351607:ACEL RS09755
gene id: 351607:ACEL_RS09755
uniprot id: A0LW52
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS06310
gene id: 351607:ACEL_RS06310
uniprot id: A0LU90
names: Similarity
messages: Belongs to the UPF0749 family.

351607:ACEL RS06515
gene id: 351607:ACEL_RS06515
uniprot id: A0LUC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351607:ACEL RS05075
gene id: 351607:ACEL_RS05075
uniprot id: A0LTJ8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

351607:ACEL RS04035
gene id: 351607:ACEL_RS04035
uniprot id: A0LSZ6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

351607:ACEL RS08640
gene id: 351607:ACEL_RS08640
uniprot id: A0LVI8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

351607:ACEL RS12460
gene id: 351607:ACEL_RS12460
uniprot id: A0LVL3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

351607:ACEL RS08545
gene id: 351607:ACEL_RS08545
uniprot id: A0LVG8
names: Similarity
messages: Belongs to the PrpD family.

351607:ACEL RS01575
gene id: 351607:ACEL_RS01575
uniprot id: A0LRL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

351607:ACEL RS06490
gene id: 351607:ACEL_RS06490
uniprot id: A0LUC2
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

351607:ACEL RS04315
gene id: 351607:ACEL_RS04315
uniprot id: A0LT47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

351607:ACEL RS06890
gene id: 351607:ACEL_RS06890
uniprot id: A0LUK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS00390
gene id: 351607:ACEL_RS00390
uniprot id: A0LQY9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase group 1 family. MshA subfamily.
messages: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
messages: Homodimer.

351607:ACEL RS06145
gene id: 351607:ACEL_RS06145
uniprot id: A0LU57
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10590
gene id: 351607:ACEL_RS10590
uniprot id: A0LWL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS06595
gene id: 351607:ACEL_RS06595
uniprot id: A0LUE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS03250
gene id: 351607:ACEL_RS03250
uniprot id: A0LSJ4
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

351607:ACEL RS02375
gene id: 351607:ACEL_RS02375
uniprot id: A0LS22
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04205
gene id: 351607:ACEL_RS04205
uniprot id: A0LT27
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

351607:ACEL RS02795
gene id: 351607:ACEL_RS02795
uniprot id: A0LSA6
names: Similarity
messages: Belongs to the CsoR family.

351607:ACEL RS07725
gene id: 351607:ACEL_RS07725
uniprot id: A0LV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

351607:ACEL RS04755
gene id: 351607:ACEL_RS04755
uniprot id: A0LTD3
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

351607:ACEL RS07670
gene id: 351607:ACEL_RS07670
uniprot id: A0LV02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

351607:ACEL RS00165
gene id: 351607:ACEL_RS00165
uniprot id: A0LQU6
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

351607:ACEL RS05710
gene id: 351607:ACEL_RS05710
uniprot id: A0LTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

351607:ACEL RS06575
gene id: 351607:ACEL_RS06575
uniprot id: A0LUD9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

351607:ACEL RS02535
gene id: 351607:ACEL_RS02535
uniprot id: A0LS53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

351607:ACEL RS06560
gene id: 351607:ACEL_RS06560
uniprot id: A0LUD6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

351607:ACEL RS00190
gene id: 351607:ACEL_RS00190
uniprot id: A0LQV1
names: Function
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: May catalyze the transamination reaction in phenylalanine biosynthesis.

351607:ACEL RS08085
gene id: 351607:ACEL_RS08085
uniprot id: A0LV82
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

351607:ACEL RS03595
gene id: 351607:ACEL_RS03595
uniprot id: A0LSR2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

351607:ACEL RS06550
gene id: 351607:ACEL_RS06550
uniprot id: A0LUD4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

351607:ACEL RS03730
gene id: 351607:ACEL_RS03730
uniprot id: A0LST7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04785
gene id: 351607:ACEL_RS04785
uniprot id: A0LTD9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

351607:ACEL RS02770
gene id: 351607:ACEL_RS02770
uniprot id: A0LSA1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351607:ACEL RS06115
gene id: 351607:ACEL_RS06115
uniprot id: A0LU51
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
messages: Cytoplasm
messages: The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.
messages: The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.

351607:ACEL RS04305
gene id: 351607:ACEL_RS04305
uniprot id: A0LT45
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

351607:ACEL RS03760
gene id: 351607:ACEL_RS03760
uniprot id: A0LSU3
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00530
gene id: 351607:ACEL_RS00530
uniprot id: A0LR16
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

351607:ACEL RS05575
gene id: 351607:ACEL_RS05575
uniprot id: A0LTU5
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04945
gene id: 351607:ACEL_RS04945
uniprot id: A0LTH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

351607:ACEL RS02205
gene id: 351607:ACEL_RS02205
uniprot id: A0LRY9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00385
gene id: 351607:ACEL_RS00385
uniprot id: A0LQY8
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

351607:ACEL RS01785
gene id: 351607:ACEL_RS01785
uniprot id: A0LRQ8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS03895
gene id: 351607:ACEL_RS03895
uniprot id: A0LSX0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

351607:ACEL RS03805
gene id: 351607:ACEL_RS03805
uniprot id: A0LSV2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

351607:ACEL RS06040
gene id: 351607:ACEL_RS06040
uniprot id: A0LU36
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

351607:ACEL RS08960
gene id: 351607:ACEL_RS08960
uniprot id: A0LVQ1
names: Similarity
messages: Belongs to the GSP E family.

351607:ACEL RS08050
gene id: 351607:ACEL_RS08050
uniprot id: A0LV75
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

351607:ACEL RS01875
gene id: 351607:ACEL_RS01875
uniprot id: A0LRS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

351607:ACEL RS04325
gene id: 351607:ACEL_RS04325
uniprot id: A0LT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

351607:ACEL RS02430
gene id: 351607:ACEL_RS02430
uniprot id: A0LS33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS00710
gene id: 351607:ACEL_RS00710
uniprot id: A0LR50
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

351607:ACEL RS07600
gene id: 351607:ACEL_RS07600
uniprot id: A0LUY8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

351607:ACEL RS10230
gene id: 351607:ACEL_RS10230
uniprot id: A0LWE4
names: Similarity
messages: Belongs to the GSP E family.

351607:ACEL RS06485
gene id: 351607:ACEL_RS06485
uniprot id: A0LUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

351607:ACEL RS01250
gene id: 351607:ACEL_RS01250
uniprot id: A0LRF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

351607:ACEL RS01555
gene id: 351607:ACEL_RS01555
uniprot id: A0LRL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351607:ACEL RS10485
gene id: 351607:ACEL_RS10485
uniprot id: A0LWI9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01720
gene id: 351607:ACEL_RS01720
uniprot id: A0LRP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

351607:ACEL RS03360
gene id: 351607:ACEL_RS03360
uniprot id: A0LSL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

351607:ACEL RS11185
gene id: 351607:ACEL_RS11185
uniprot id: A0LWW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.

351607:ACEL RS03855
gene id: 351607:ACEL_RS03855
uniprot id: A0LSW2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

351607:ACEL RS05750
gene id: 351607:ACEL_RS05750
uniprot id: A0LTY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS04265
gene id: 351607:ACEL_RS04265
uniprot id: A0LT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS07970
gene id: 351607:ACEL_RS07970
uniprot id: A0LV59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

351607:ACEL RS06355
gene id: 351607:ACEL_RS06355
uniprot id: A0LU98
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

351607:ACEL RS07980
gene id: 351607:ACEL_RS07980
uniprot id: A0LV61
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

351607:ACEL RS09515
gene id: 351607:ACEL_RS09515
uniprot id: A0LW04
names: Similarity
messages: Belongs to the LOG family.

351607:ACEL RS06830
gene id: 351607:ACEL_RS06830
uniprot id: A0LUJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

351607:ACEL RS03345
gene id: 351607:ACEL_RS03345
uniprot id: A0LSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

351607:ACEL RS02615
gene id: 351607:ACEL_RS02615
uniprot id: A0LS69
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS05335
gene id: 351607:ACEL_RS05335
uniprot id: A0LTP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

351607:ACEL RS07340
gene id: 351607:ACEL_RS07340
uniprot id: A0LUT7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

351607:ACEL RS00400
gene id: 351607:ACEL_RS00400
uniprot id: A0LQZ1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

351607:ACEL RS00340
gene id: 351607:ACEL_RS00340
uniprot id: A0LQX9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS07225
gene id: 351607:ACEL_RS07225
uniprot id: A0LUR4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

351607:ACEL RS03790
gene id: 351607:ACEL_RS03790
uniprot id: A0LSU9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

351607:ACEL RS09740
gene id: 351607:ACEL_RS09740
uniprot id: A0LW49
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

351607:ACEL RS08685
gene id: 351607:ACEL_RS08685
uniprot id: A0LVJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

351607:ACEL RS01325
gene id: 351607:ACEL_RS01325
uniprot id: A0LRG9
names: Similarity
messages: Belongs to the UbiD family.

351607:ACEL RS09625
gene id: 351607:ACEL_RS09625
uniprot id: A0LW26
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

351607:ACEL RS05450
gene id: 351607:ACEL_RS05450
uniprot id: A0LTS2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

351607:ACEL RS09645
gene id: 351607:ACEL_RS09645
uniprot id: A0LW30
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MshB deacetylase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.

351607:ACEL RS00245
gene id: 351607:ACEL_RS00245
uniprot id: A0LQW1
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS06580
gene id: 351607:ACEL_RS06580
uniprot id: A0LUE0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

351607:ACEL RS11040
gene id: 351607:ACEL_RS11040
uniprot id: A0LWT9
names: Similarity
messages: Belongs to the GARS family.

351607:ACEL RS01395
gene id: 351607:ACEL_RS01395
uniprot id: A0LRI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS00620
gene id: 351607:ACEL_RS00620
uniprot id: A0LR34
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

351607:ACEL RS06915
gene id: 351607:ACEL_RS06915
uniprot id: A0LUK6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

351607:ACEL RS07925
gene id: 351607:ACEL_RS07925
uniprot id: A0LV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

351607:ACEL RS07935
gene id: 351607:ACEL_RS07935
uniprot id: A0LV52
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

351607:ACEL RS09305
gene id: 351607:ACEL_RS09305
uniprot id: A0LVW2
names: Similarity
messages: Belongs to the TPP enzyme family.

351607:ACEL RS09820
gene id: 351607:ACEL_RS09820
uniprot id: A0LW64
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

351607:ACEL RS01550
gene id: 351607:ACEL_RS01550
uniprot id: A0LRL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

351607:ACEL RS00225
gene id: 351607:ACEL_RS00225
uniprot id: A0LQV7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01345
gene id: 351607:ACEL_RS01345
uniprot id: A0LRH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

351607:ACEL RS08330
gene id: 351607:ACEL_RS08330
uniprot id: A0LVC8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

351607:ACEL RS00595
gene id: 351607:ACEL_RS00595
uniprot id: A0LR29
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10865
gene id: 351607:ACEL_RS10865
uniprot id: A0LWR0
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

351607:ACEL RS10930
gene id: 351607:ACEL_RS10930
uniprot id: A0LWS1
names: Similarity
messages: Belongs to the UPF0145 family.

351607:ACEL RS01525
gene id: 351607:ACEL_RS01525
uniprot id: A0LRK6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

351607:ACEL RS11015
gene id: 351607:ACEL_RS11015
uniprot id: A0LWT4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

351607:ACEL RS08700
gene id: 351607:ACEL_RS08700
uniprot id: A0LVJ9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

351607:ACEL RS05940
gene id: 351607:ACEL_RS05940
uniprot id: A0LU18
names: Similarity
messages: Belongs to the band 7/mec-2 family.

351607:ACEL RS04320
gene id: 351607:ACEL_RS04320
uniprot id: A0LT48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

351607:ACEL RS00555
gene id: 351607:ACEL_RS00555
uniprot id: A0LR21
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

351607:ACEL RS03945
gene id: 351607:ACEL_RS03945
uniprot id: A0LSX9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

351607:ACEL RS02355
gene id: 351607:ACEL_RS02355
uniprot id: A0LS17
names: Similarity
messages: Belongs to the DDAH family.

351607:ACEL RS04670
gene id: 351607:ACEL_RS04670
uniprot id: A0LTB6
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS06225
gene id: 351607:ACEL_RS06225
uniprot id: A0LU74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase-binding protein RbpA family.
messages: Bind 1 Zn(2+) per subunit.
messages: Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.
messages: Forms a complex with the RNAP catalytic core and with free principal sigma factors.

351607:ACEL RS03905
gene id: 351607:ACEL_RS03905
uniprot id: A0LSX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

351607:ACEL RS06130
gene id: 351607:ACEL_RS06130
uniprot id: A0LU54
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

351607:ACEL RS08790
gene id: 351607:ACEL_RS08790
uniprot id: A0LVL6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

351607:ACEL RS06325
gene id: 351607:ACEL_RS06325
uniprot id: A0LU93
names: Similarity
messages: Belongs to the phosphohexose mutase family.

351607:ACEL RS08765
gene id: 351607:ACEL_RS08765
uniprot id: A0LVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

351607:ACEL RS12755
gene id: 351607:ACEL_RS12755
uniprot id: A0LT42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

351607:ACEL RS06675
gene id: 351607:ACEL_RS06675
uniprot id: A0LUF9
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

351607:ACEL RS01195
gene id: 351607:ACEL_RS01195
uniprot id: A0LRE2
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

351607:ACEL RS01580
gene id: 351607:ACEL_RS01580
uniprot id: A0LRL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

351607:ACEL RS08160
gene id: 351607:ACEL_RS08160
uniprot id: A0LV98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

351607:ACEL RS11060
gene id: 351607:ACEL_RS11060
uniprot id: A0LWU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

351607:ACEL RS09920
gene id: 351607:ACEL_RS09920
uniprot id: A0LW84
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10740
gene id: 351607:ACEL_RS10740
uniprot id: A0LWN4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

351607:ACEL RS06460
gene id: 351607:ACEL_RS06460
uniprot id: A0LUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS04435
gene id: 351607:ACEL_RS04435
uniprot id: A0LT70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

351607:ACEL RS00585
gene id: 351607:ACEL_RS00585
uniprot id: A0LR27
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

351607:ACEL RS02105
gene id: 351607:ACEL_RS02105
uniprot id: A0LRX1
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

351607:ACEL RS06695
gene id: 351607:ACEL_RS06695
uniprot id: A0LUG3
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

351607:ACEL RS07045
gene id: 351607:ACEL_RS07045
uniprot id: A0LUN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SsgA family.
messages: Cell septum

351607:ACEL RS01085
gene id: 351607:ACEL_RS01085
uniprot id: A0LRC0
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10735
gene id: 351607:ACEL_RS10735
uniprot id: A0LWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

351607:ACEL RS10010
gene id: 351607:ACEL_RS10010
uniprot id: A0LWA0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

351607:ACEL RS07940
gene id: 351607:ACEL_RS07940
uniprot id: A0LV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

351607:ACEL RS05555
gene id: 351607:ACEL_RS05555
uniprot id: A0LTU2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

351607:ACEL RS07930
gene id: 351607:ACEL_RS07930
uniprot id: A0LV51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

351607:ACEL RS07615
gene id: 351607:ACEL_RS07615
uniprot id: A0LUZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

351607:ACEL RS08745
gene id: 351607:ACEL_RS08745
uniprot id: A0LVK8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

351607:ACEL RS06925
gene id: 351607:ACEL_RS06925
uniprot id: A0LUK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

351607:ACEL RS05205
gene id: 351607:ACEL_RS05205
uniprot id: A0LTM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

351607:ACEL RS03660
gene id: 351607:ACEL_RS03660
uniprot id: A0LSS5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

351607:ACEL RS04390
gene id: 351607:ACEL_RS04390
uniprot id: A0LT61
names: Similarity
messages: Belongs to the FlgD family.

351607:ACEL RS00605
gene id: 351607:ACEL_RS00605
uniprot id: A0LR31
names: Similarity
messages: Belongs to the citrate synthase family.

351607:ACEL RS00995
gene id: 351607:ACEL_RS00995
uniprot id: A0LRA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

351607:ACEL RS08845
gene id: 351607:ACEL_RS08845
uniprot id: A0LVM7
names: Similarity
messages: Belongs to the shaker potassium channel beta subunit family.

351607:ACEL RS06895
gene id: 351607:ACEL_RS06895
uniprot id: A0LUK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

351607:ACEL RS11460
gene id: 351607:ACEL_RS11460
uniprot id: A0LTP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

351607:ACEL RS06670
gene id: 351607:ACEL_RS06670
uniprot id: A0LUF8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01705
gene id: 351607:ACEL_RS01705
uniprot id: A0LRP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS10185
gene id: 351607:ACEL_RS10185
uniprot id: A0LWD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

351607:ACEL RS07135
gene id: 351607:ACEL_RS07135
uniprot id: A0LUP6
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS03835
gene id: 351607:ACEL_RS03835
uniprot id: A0LSV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS06800
gene id: 351607:ACEL_RS06800
uniprot id: A0LUI4
names: Similarity
messages: Belongs to the GSP E family.

351607:ACEL RS06235
gene id: 351607:ACEL_RS06235
uniprot id: A0LU76
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

351607:ACEL RS11075
gene id: 351607:ACEL_RS11075
uniprot id: A0LWU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

351607:ACEL RS12795
gene id: 351607:ACEL_RS12795
uniprot id: A0LVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS10700
gene id: 351607:ACEL_RS10700
uniprot id: A0LWM6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS03570
gene id: 351607:ACEL_RS03570
uniprot id: A0LSQ7
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

351607:ACEL RS00010
gene id: 351607:ACEL_RS00010
uniprot id: A0LQR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

351607:ACEL RS01005
gene id: 351607:ACEL_RS01005
uniprot id: A0LRA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DyP-type peroxidase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.
messages: Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact.

351607:ACEL RS10045
gene id: 351607:ACEL_RS10045
uniprot id: A0LWA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

351607:ACEL RS05835
gene id: 351607:ACEL_RS05835
uniprot id: A0LTZ7
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

351607:ACEL RS02275
gene id: 351607:ACEL_RS02275
uniprot id: A0LS03
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS06645
gene id: 351607:ACEL_RS06645
uniprot id: A0LUF3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01850
gene id: 351607:ACEL_RS01850
uniprot id: A0LRS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

351607:ACEL RS05725
gene id: 351607:ACEL_RS05725
uniprot id: A0LTX5
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

351607:ACEL RS06160
gene id: 351607:ACEL_RS06160
uniprot id: A0LU60
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

351607:ACEL RS07010
gene id: 351607:ACEL_RS07010
uniprot id: A0LUM5
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

351607:ACEL RS07635
gene id: 351607:ACEL_RS07635
uniprot id: A0LUZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS09410
gene id: 351607:ACEL_RS09410
uniprot id: A0LVY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

351607:ACEL RS02880
gene id: 351607:ACEL_RS02880
uniprot id: A0LSC3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

351607:ACEL RS08140
gene id: 351607:ACEL_RS08140
uniprot id: A0LV94
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

351607:ACEL RS02750
gene id: 351607:ACEL_RS02750
uniprot id: A0LS97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

351607:ACEL RS03860
gene id: 351607:ACEL_RS03860
uniprot id: A0LSW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

351607:ACEL RS01425
gene id: 351607:ACEL_RS01425
uniprot id: A0LRI9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS04770
gene id: 351607:ACEL_RS04770
uniprot id: A0LTD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

351607:ACEL RS00675
gene id: 351607:ACEL_RS00675
uniprot id: A0LR43
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

351607:ACEL RS05745
gene id: 351607:ACEL_RS05745
uniprot id: A0LTX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS07780
gene id: 351607:ACEL_RS07780
uniprot id: A0LV21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

351607:ACEL RS02760
gene id: 351607:ACEL_RS02760
uniprot id: A0LS99
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

351607:ACEL RS00840
gene id: 351607:ACEL_RS00840
uniprot id: A0LR74
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

351607:ACEL RS01725
gene id: 351607:ACEL_RS01725
uniprot id: A0LRP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

351607:ACEL RS08925
gene id: 351607:ACEL_RS08925
uniprot id: A0LVP4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

351607:ACEL RS05285
gene id: 351607:ACEL_RS05285
uniprot id: A0LTN9
names: Similarity
messages: Belongs to the YggT family.

351607:ACEL RS00845
gene id: 351607:ACEL_RS00845
uniprot id: A0LR75
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

351607:ACEL RS05085
gene id: 351607:ACEL_RS05085
uniprot id: A0LTK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

351607:ACEL RS09120
gene id: 351607:ACEL_RS09120
uniprot id: A0LVS6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

351607:ACEL RS02790
gene id: 351607:ACEL_RS02790
uniprot id: A0LSA5
names: Similarity
messages: Belongs to the thioredoxin family.

351607:ACEL RS09350
gene id: 351607:ACEL_RS09350
uniprot id: A0LVX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family.
messages: Homotetramer.
messages: Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).

351607:ACEL RS04495
gene id: 351607:ACEL_RS04495
uniprot id: A0LT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

351607:ACEL RS01540
gene id: 351607:ACEL_RS01540
uniprot id: A0LRK8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

351607:ACEL RS08095
gene id: 351607:ACEL_RS08095
uniprot id: A0LV84
names: Similarity
messages: Belongs to the acylphosphatase family.

351607:ACEL RS03525
gene id: 351607:ACEL_RS03525
uniprot id: A0LSP8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

351607:ACEL RS04125
gene id: 351607:ACEL_RS04125
uniprot id: A0LT14
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

351607:ACEL RS05505
gene id: 351607:ACEL_RS05505
uniprot id: A0LTT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS01685
gene id: 351607:ACEL_RS01685
uniprot id: A0LRN7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

351607:ACEL RS06685
gene id: 351607:ACEL_RS06685
uniprot id: A0LUG1
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

351607:ACEL RS10265
gene id: 351607:ACEL_RS10265
uniprot id: A0LWF0
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS11270
gene id: 351607:ACEL_RS11270
uniprot id: A0LR60
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS05885
gene id: 351607:ACEL_RS05885
uniprot id: A0LU07
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

351607:ACEL RS03205
gene id: 351607:ACEL_RS03205
uniprot id: A0LSI7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

351607:ACEL RS05190
gene id: 351607:ACEL_RS05190
uniprot id: A0LTM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

351607:ACEL RS11035
gene id: 351607:ACEL_RS11035
uniprot id: A0LWT8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

351607:ACEL RS10620
gene id: 351607:ACEL_RS10620
uniprot id: A0LWL6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

351607:ACEL RS07995
gene id: 351607:ACEL_RS07995
uniprot id: A0LV64
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

351607:ACEL RS08555
gene id: 351607:ACEL_RS08555
uniprot id: A0LVH0
names: Similarity
messages: Belongs to the citrate synthase family.

351607:ACEL RS07085
gene id: 351607:ACEL_RS07085
uniprot id: A0LUN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

351607:ACEL RS08520
gene id: 351607:ACEL_RS08520
uniprot id: A0LVG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane
messages: Membrane

351607:ACEL RS05935
gene id: 351607:ACEL_RS05935
uniprot id: A0LU17
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS11005
gene id: 351607:ACEL_RS11005
uniprot id: A0LWT2
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

351607:ACEL RS05850
gene id: 351607:ACEL_RS05850
uniprot id: A0LU00
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

351607:ACEL RS05105
gene id: 351607:ACEL_RS05105
uniprot id: A0LTK4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

351607:ACEL RS00880
gene id: 351607:ACEL_RS00880
uniprot id: A0LR82
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

351607:ACEL RS03520
gene id: 351607:ACEL_RS03520
uniprot id: A0LSP7
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta subunit.
messages: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

351607:ACEL RS05455
gene id: 351607:ACEL_RS05455
uniprot id: A0LTS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

351607:ACEL RS00815
gene id: 351607:ACEL_RS00815
uniprot id: A0LR69
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

351607:ACEL RS03295
gene id: 351607:ACEL_RS03295
uniprot id: A0LSK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351607:ACEL RS08620
gene id: 351607:ACEL_RS08620
uniprot id: A0LVI4
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide to form bicarbonate.

351607:ACEL RS08025
gene id: 351607:ACEL_RS08025
uniprot id: A0LV70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

351607:ACEL RS03095
gene id: 351607:ACEL_RS03095
uniprot id: A0LSG8
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS09535
gene id: 351607:ACEL_RS09535
uniprot id: A0LW08
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

351607:ACEL RS02600
gene id: 351607:ACEL_RS02600
uniprot id: A0LS66
names: Similarity
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Homotrimer.

351607:ACEL RS10440
gene id: 351607:ACEL_RS10440
uniprot id: A0LWI0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

351607:ACEL RS06470
gene id: 351607:ACEL_RS06470
uniprot id: A0LUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

351607:ACEL RS01405
gene id: 351607:ACEL_RS01405
uniprot id: A0LRI5
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.

351607:ACEL RS10290
gene id: 351607:ACEL_RS10290
uniprot id: A0LWF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

351607:ACEL RS05905
gene id: 351607:ACEL_RS05905
uniprot id: A0LU11
names: Similarity
messages: Belongs to the peptidase U62 family.

351607:ACEL RS06710
gene id: 351607:ACEL_RS06710
uniprot id: A0LUG6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

351607:ACEL RS01240
gene id: 351607:ACEL_RS01240
uniprot id: A0LRF1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

351607:ACEL RS03315
gene id: 351607:ACEL_RS03315
uniprot id: A0LSK7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00825
gene id: 351607:ACEL_RS00825
uniprot id: A0LR71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscL family.
messages: Membrane

351607:ACEL RS06330
gene id: 351607:ACEL_RS06330
uniprot id: A0LU94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

351607:ACEL RS04350
gene id: 351607:ACEL_RS04350
uniprot id: A0LT54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

351607:ACEL RS10750
gene id: 351607:ACEL_RS10750
uniprot id: A0LWN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

351607:ACEL RS04415
gene id: 351607:ACEL_RS04415
uniprot id: A0LT66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

351607:ACEL RS07035
gene id: 351607:ACEL_RS07035
uniprot id: A0LUN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS10900
gene id: 351607:ACEL_RS10900
uniprot id: A0LWR6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

351607:ACEL RS05690
gene id: 351607:ACEL_RS05690
uniprot id: A0LTW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

351607:ACEL RS08875
gene id: 351607:ACEL_RS08875
uniprot id: A0LVN5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS10545
gene id: 351607:ACEL_RS10545
uniprot id: A0LWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

351607:ACEL RS10780
gene id: 351607:ACEL_RS10780
uniprot id: A0LWP3
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS02125
gene id: 351607:ACEL_RS02125
uniprot id: A0LRX5
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

351607:ACEL RS06910
gene id: 351607:ACEL_RS06910
uniprot id: A0LUK5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

351607:ACEL RS09440
gene id: 351607:ACEL_RS09440
uniprot id: A0LVY8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

351607:ACEL RS02065
gene id: 351607:ACEL_RS02065
uniprot id: A0LRW4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

351607:ACEL RS07480
gene id: 351607:ACEL_RS07480
uniprot id: A0LUW3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

351607:ACEL RS00490
gene id: 351607:ACEL_RS00490
uniprot id: A0LR08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

351607:ACEL RS07585
gene id: 351607:ACEL_RS07585
uniprot id: A0LUY5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

351607:ACEL RS07075
gene id: 351607:ACEL_RS07075
uniprot id: A0LUN4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

351607:ACEL RS05250
gene id: 351607:ACEL_RS05250
uniprot id: A0LTN3
names: Similarity
messages: Belongs to the peptidase A31 family.

351607:ACEL RS07945
gene id: 351607:ACEL_RS07945
uniprot id: A0LV54
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

351607:ACEL RS04835
gene id: 351607:ACEL_RS04835
uniprot id: A0LTE9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

351607:ACEL RS00030
gene id: 351607:ACEL_RS00030
uniprot id: A0LQS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

351607:ACEL RS02685
gene id: 351607:ACEL_RS02685
uniprot id: A0LS84
names: Similarity
messages: Belongs to the XFP family.

351607:ACEL RS02420
gene id: 351607:ACEL_RS02420
uniprot id: A0LS31
names: Similarity
messages: Belongs to the PGI/PMI family.

351607:ACEL RS11145
gene id: 351607:ACEL_RS11145
uniprot id: A0LWW0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

351607:ACEL RS07605
gene id: 351607:ACEL_RS07605
uniprot id: A0LUY9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

351607:ACEL RS04445
gene id: 351607:ACEL_RS04445
uniprot id: A0LT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

351607:ACEL RS08120
gene id: 351607:ACEL_RS08120
uniprot id: A0LV90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

351607:ACEL RS08955
gene id: 351607:ACEL_RS08955
uniprot id: A0LVQ0
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04345
gene id: 351607:ACEL_RS04345
uniprot id: A0LT53
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

351607:ACEL RS02425
gene id: 351607:ACEL_RS02425
uniprot id: A0LS32
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

351607:ACEL RS08625
gene id: 351607:ACEL_RS08625
uniprot id: A0LVI5
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00085
gene id: 351607:ACEL_RS00085
uniprot id: A0LQT1
names: Similarity
messages: Belongs to the UPF0749 family.

351607:ACEL RS01695
gene id: 351607:ACEL_RS01695
uniprot id: A0LRN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

351607:ACEL RS03930
gene id: 351607:ACEL_RS03930
uniprot id: A0LSX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

351607:ACEL RS06075
gene id: 351607:ACEL_RS06075
uniprot id: A0LU43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

351607:ACEL RS05795
gene id: 351607:ACEL_RS05795
uniprot id: A0LTY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

351607:ACEL RS01055
gene id: 351607:ACEL_RS01055
uniprot id: A0LRB4
names: Similarity
messages: Belongs to the peptidase S13 family.

351607:ACEL RS07320
gene id: 351607:ACEL_RS07320
uniprot id: A0LUT3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

351607:ACEL RS01790
gene id: 351607:ACEL_RS01790
uniprot id: A0LRQ9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01920
gene id: 351607:ACEL_RS01920
uniprot id: A0LRT5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

351607:ACEL RS10110
gene id: 351607:ACEL_RS10110
uniprot id: A0LWB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

351607:ACEL RS00015
gene id: 351607:ACEL_RS00015
uniprot id: A0LQR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

351607:ACEL RS08495
gene id: 351607:ACEL_RS08495
uniprot id: A0LVG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

351607:ACEL RS08040
gene id: 351607:ACEL_RS08040
uniprot id: A0LV73
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

351607:ACEL RS04970
gene id: 351607:ACEL_RS04970
uniprot id: A0LTH6
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

351607:ACEL RS06475
gene id: 351607:ACEL_RS06475
uniprot id: A0LUB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

351607:ACEL RS06930
gene id: 351607:ACEL_RS06930
uniprot id: A0LUK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

351607:ACEL RS08885
gene id: 351607:ACEL_RS08885
uniprot id: A0LVN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

351607:ACEL RS05770
gene id: 351607:ACEL_RS05770
uniprot id: A0LTY4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

351607:ACEL RS01745
gene id: 351607:ACEL_RS01745
uniprot id: A0LRQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS05305
gene id: 351607:ACEL_RS05305
uniprot id: A0LTP2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

351607:ACEL RS01230
gene id: 351607:ACEL_RS01230
uniprot id: A0LRE9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

351607:ACEL RS05730
gene id: 351607:ACEL_RS05730
uniprot id: A0LTX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Cytoplasm

351607:ACEL RS05915
gene id: 351607:ACEL_RS05915
uniprot id: A0LU13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

351607:ACEL RS03740
gene id: 351607:ACEL_RS03740
uniprot id: A0LST9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS02830
gene id: 351607:ACEL_RS02830
uniprot id: A0LSB3
names: Similarity
messages: Belongs to the GSP E family.

351607:ACEL RS04100
gene id: 351607:ACEL_RS04100
uniprot id: A0LT09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

351607:ACEL RS07845
gene id: 351607:ACEL_RS07845
uniprot id: A0LV34
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

351607:ACEL RS03510
gene id: 351607:ACEL_RS03510
uniprot id: A0LSP5
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

351607:ACEL RS08390
gene id: 351607:ACEL_RS08390
uniprot id: A0LVE0
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

351607:ACEL RS07185
gene id: 351607:ACEL_RS07185
uniprot id: A0LUQ6
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

351607:ACEL RS06125
gene id: 351607:ACEL_RS06125
uniprot id: A0LU53
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
messages: Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
messages: The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group.

351607:ACEL RS10630
gene id: 351607:ACEL_RS10630
uniprot id: A0LWL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

351607:ACEL RS09990
gene id: 351607:ACEL_RS09990
uniprot id: A0LW96
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

351607:ACEL RS01065
gene id: 351607:ACEL_RS01065
uniprot id: A0LRB6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

351607:ACEL RS08510
gene id: 351607:ACEL_RS08510
uniprot id: A0LVG2
names: Similarity
messages: Belongs to the CsoR family.

351607:ACEL RS11195
gene id: 351607:ACEL_RS11195
uniprot id: A0LWX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

351607:ACEL RS01865
gene id: 351607:ACEL_RS01865
uniprot id: A0LRS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

351607:ACEL RS07750
gene id: 351607:ACEL_RS07750
uniprot id: A0LV15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

351607:ACEL RS05155
gene id: 351607:ACEL_RS05155
uniprot id: A0LTL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

351607:ACEL RS01020
gene id: 351607:ACEL_RS01020
uniprot id: A0LRA7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10195
gene id: 351607:ACEL_RS10195
uniprot id: A0LWD7
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

351607:ACEL RS01675
gene id: 351607:ACEL_RS01675
uniprot id: A0LRN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

351607:ACEL RS06665
gene id: 351607:ACEL_RS06665
uniprot id: A0LUF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

351607:ACEL RS09690
gene id: 351607:ACEL_RS09690
uniprot id: A0LW39
names: Similarity
messages: Belongs to the FBPase class 2 family.

351607:ACEL RS12585
gene id: 351607:ACEL_RS12585
uniprot id: A0LT59
names: Similarity
messages: Belongs to the peptidase C40 family.
messages: Belongs to the transglycosylase Slt family.

351607:ACEL RS05160
gene id: 351607:ACEL_RS05160
uniprot id: A0LTL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

351607:ACEL RS09615
gene id: 351607:ACEL_RS09615
uniprot id: A0LW24
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

351607:ACEL RS01965
gene id: 351607:ACEL_RS01965
uniprot id: A0LRU4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

351607:ACEL RS05175
gene id: 351607:ACEL_RS05175
uniprot id: A0LTL8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS12705
gene id: 351607:ACEL_RS12705
uniprot id: A0LWH9
names: Subcellular Location Annotation
messages: Cytoplasm

351607:ACEL RS04985
gene id: 351607:ACEL_RS04985
uniprot id: A0LTH9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

351607:ACEL RS04690
gene id: 351607:ACEL_RS04690
uniprot id: A0LTC0
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS08100
gene id: 351607:ACEL_RS08100
uniprot id: A0LV85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

351607:ACEL RS08070
gene id: 351607:ACEL_RS08070
uniprot id: A0LV79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

351607:ACEL RS05415
gene id: 351607:ACEL_RS05415
uniprot id: A0LTR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01560
gene id: 351607:ACEL_RS01560
uniprot id: A0LRL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

351607:ACEL RS06525
gene id: 351607:ACEL_RS06525
uniprot id: A0LUC9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

351607:ACEL RS03585
gene id: 351607:ACEL_RS03585
uniprot id: A0LSR0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

351607:ACEL RS07590
gene id: 351607:ACEL_RS07590
uniprot id: A0LUY6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

351607:ACEL RS05100
gene id: 351607:ACEL_RS05100
uniprot id: A0LTK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

351607:ACEL RS03545
gene id: 351607:ACEL_RS03545
uniprot id: A0LSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

351607:ACEL RS05510
gene id: 351607:ACEL_RS05510
uniprot id: A0LTT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

351607:ACEL RS07125
gene id: 351607:ACEL_RS07125
uniprot id: A0LUP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS00600
gene id: 351607:ACEL_RS00600
uniprot id: A0LR30
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS01545
gene id: 351607:ACEL_RS01545
uniprot id: A0LRK9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

351607:ACEL RS10055
gene id: 351607:ACEL_RS10055
uniprot id: A0LWA9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS02010
gene id: 351607:ACEL_RS02010
uniprot id: A0LRV3
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00145
gene id: 351607:ACEL_RS00145
uniprot id: A0LQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

351607:ACEL RS04480
gene id: 351607:ACEL_RS04480
uniprot id: A0LT79
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

351607:ACEL RS03625
gene id: 351607:ACEL_RS03625
uniprot id: A0LSR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

351607:ACEL RS01730
gene id: 351607:ACEL_RS01730
uniprot id: A0LRP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

351607:ACEL RS02005
gene id: 351607:ACEL_RS02005
uniprot id: A0LRV2
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

351607:ACEL RS04790
gene id: 351607:ACEL_RS04790
uniprot id: A0LTE0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

351607:ACEL RS03990
gene id: 351607:ACEL_RS03990
uniprot id: A0LSY7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS06530
gene id: 351607:ACEL_RS06530
uniprot id: A0LUD0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

351607:ACEL RS05705
gene id: 351607:ACEL_RS05705
uniprot id: A0LTX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

351607:ACEL RS01130
gene id: 351607:ACEL_RS01130
uniprot id: A0LRC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

351607:ACEL RS10180
gene id: 351607:ACEL_RS10180
uniprot id: A0LWD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

351607:ACEL RS04530
gene id: 351607:ACEL_RS04530
uniprot id: A0LT89
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

351607:ACEL RS05435
gene id: 351607:ACEL_RS05435
uniprot id: A0LTR9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00885
gene id: 351607:ACEL_RS00885
uniprot id: A0LR83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

351607:ACEL RS10455
gene id: 351607:ACEL_RS10455
uniprot id: A0LWI3
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

351607:ACEL RS06080
gene id: 351607:ACEL_RS06080
uniprot id: A0LU44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
messages: Homotetramer composed of a dimer of dimers.

351607:ACEL RS00535
gene id: 351607:ACEL_RS00535
uniprot id: A0LR17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

351607:ACEL RS01290
gene id: 351607:ACEL_RS01290
uniprot id: A0LRG2
names: Cofactor
messages: Binds 1 FAD per subunit.

351607:ACEL RS09775
gene id: 351607:ACEL_RS09775
uniprot id: A0LW56
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS06585
gene id: 351607:ACEL_RS06585
uniprot id: A0LUE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

351607:ACEL RS03340
gene id: 351607:ACEL_RS03340
uniprot id: A0LSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

351607:ACEL RS09500
gene id: 351607:ACEL_RS09500
uniprot id: A0LW01
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

351607:ACEL RS01905
gene id: 351607:ACEL_RS01905
uniprot id: A0LRT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS05970
gene id: 351607:ACEL_RS05970
uniprot id: A0LU24
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01435
gene id: 351607:ACEL_RS01435
uniprot id: A0LRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS06230
gene id: 351607:ACEL_RS06230
uniprot id: A0LU75
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

351607:ACEL RS06345
gene id: 351607:ACEL_RS06345
uniprot id: A0LU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

351607:ACEL RS12370
gene id: 351607:ACEL_RS12370
uniprot id: A0LRA0
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01680
gene id: 351607:ACEL_RS01680
uniprot id: A0LRN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

351607:ACEL RS11000
gene id: 351607:ACEL_RS11000
uniprot id: A0LWT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

351607:ACEL RS03475
gene id: 351607:ACEL_RS03475
uniprot id: A0LSN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

351607:ACEL RS01645
gene id: 351607:ACEL_RS01645
uniprot id: A0LRM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

351607:ACEL RS01450
gene id: 351607:ACEL_RS01450
uniprot id: A0LRJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS03465
gene id: 351607:ACEL_RS03465
uniprot id: A0LSN7
names: Subunit
messages: Heterodimer of an alpha and a beta chain.

351607:ACEL RS12735
gene id: 351607:ACEL_RS12735
uniprot id: A0LRP9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

351607:ACEL RS05580
gene id: 351607:ACEL_RS05580
uniprot id: A0LTU6
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00700
gene id: 351607:ACEL_RS00700
uniprot id: A0LR48
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

351607:ACEL RS02000
gene id: 351607:ACEL_RS02000
uniprot id: A0LRV1
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

351607:ACEL RS05920
gene id: 351607:ACEL_RS05920
uniprot id: A0LU14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

351607:ACEL RS01595
gene id: 351607:ACEL_RS01595
uniprot id: A0LRL9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

351607:ACEL RS04715
gene id: 351607:ACEL_RS04715
uniprot id: A0LTC5
names: Similarity
messages: Belongs to the UPF0098 family.

351607:ACEL RS11030
gene id: 351607:ACEL_RS11030
uniprot id: A0LWT7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

351607:ACEL RS10090
gene id: 351607:ACEL_RS10090
uniprot id: A0LWB5
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

351607:ACEL RS00265
gene id: 351607:ACEL_RS00265
uniprot id: A0LQW5
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS11325
gene id: 351607:ACEL_RS11325
uniprot id: A0LRY1
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

351607:ACEL RS07905
gene id: 351607:ACEL_RS07905
uniprot id: A0LV46
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS10245
gene id: 351607:ACEL_RS10245
uniprot id: A0LWE6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS03120
gene id: 351607:ACEL_RS03120
uniprot id: A0LSH3
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

351607:ACEL RS10760
gene id: 351607:ACEL_RS10760
uniprot id: A0LWN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

351607:ACEL RS00610
gene id: 351607:ACEL_RS00610
uniprot id: A0LR32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

351607:ACEL RS06540
gene id: 351607:ACEL_RS06540
uniprot id: A0LUD2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

351607:ACEL RS04440
gene id: 351607:ACEL_RS04440
uniprot id: A0LT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

351607:ACEL RS05215
gene id: 351607:ACEL_RS05215
uniprot id: A0LTM6
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

351607:ACEL RS06720
gene id: 351607:ACEL_RS06720
uniprot id: A0LUG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

351607:ACEL RS06715
gene id: 351607:ACEL_RS06715
uniprot id: A0LUG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

351607:ACEL RS03300
gene id: 351607:ACEL_RS03300
uniprot id: A0LSK4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

351607:ACEL RS01070
gene id: 351607:ACEL_RS01070
uniprot id: A0LRB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

351607:ACEL RS09510
gene id: 351607:ACEL_RS09510
uniprot id: A0LW03
names: Similarity
messages: Belongs to the LOG family.

351607:ACEL RS05500
gene id: 351607:ACEL_RS05500
uniprot id: A0LTT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

351607:ACEL RS06510
gene id: 351607:ACEL_RS06510
uniprot id: A0LUC6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

351607:ACEL RS04535
gene id: 351607:ACEL_RS04535
uniprot id: A0LT90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

351607:ACEL RS07200
gene id: 351607:ACEL_RS07200
uniprot id: A0LUQ9
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS04045
gene id: 351607:ACEL_RS04045
uniprot id: A0LSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

351607:ACEL RS01175
gene id: 351607:ACEL_RS01175
uniprot id: A0LRD9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

351607:ACEL RS01315
gene id: 351607:ACEL_RS01315
uniprot id: A0LRG7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS00865
gene id: 351607:ACEL_RS00865
uniprot id: A0LR79
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

351607:ACEL RS10390
gene id: 351607:ACEL_RS10390
uniprot id: A0LWH3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

351607:ACEL RS10845
gene id: 351607:ACEL_RS10845
uniprot id: A0LWQ6
names: Similarity
messages: Belongs to the catalase family.

351607:ACEL RS07795
gene id: 351607:ACEL_RS07795
uniprot id: A0LV24
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

351607:ACEL RS01710
gene id: 351607:ACEL_RS01710
uniprot id: A0LRP2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

351607:ACEL RS05195
gene id: 351607:ACEL_RS05195
uniprot id: A0LTM2
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS03355
gene id: 351607:ACEL_RS03355
uniprot id: A0LSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

351607:ACEL RS10365
gene id: 351607:ACEL_RS10365
uniprot id: A0LWG9
names: Similarity
messages: Belongs to the Dps family.

351607:ACEL RS03485
gene id: 351607:ACEL_RS03485
uniprot id: A0LSP1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

351607:ACEL RS07680
gene id: 351607:ACEL_RS07680
uniprot id: A0LV04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

351607:ACEL RS00430
gene id: 351607:ACEL_RS00430
uniprot id: A0LQZ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

351607:ACEL RS01635
gene id: 351607:ACEL_RS01635
uniprot id: A0LRM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

351607:ACEL RS01235
gene id: 351607:ACEL_RS01235
uniprot id: A0LRF0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

351607:ACEL RS07120
gene id: 351607:ACEL_RS07120
uniprot id: A0LUP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

351607:ACEL RS06600
gene id: 351607:ACEL_RS06600
uniprot id: A0LUE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

351607:ACEL RS03765
gene id: 351607:ACEL_RS03765
uniprot id: A0LSU4
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS05275
gene id: 351607:ACEL_RS05275
uniprot id: A0LTN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

351607:ACEL RS03225
gene id: 351607:ACEL_RS03225
uniprot id: A0LSI9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

351607:ACEL RS08905
gene id: 351607:ACEL_RS08905
uniprot id: A0LVP1
names: Similarity
messages: Belongs to the peptidase S41A family.

351607:ACEL RS07020
gene id: 351607:ACEL_RS07020
uniprot id: A0LUM7
names: Subcellular Location Annotation
messages: Membrane

351607:ACEL RS01400
gene id: 351607:ACEL_RS01400
uniprot id: A0LRI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

351607:ACEL RS06730
gene id: 351607:ACEL_RS06730
uniprot id: A0LUH0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS05200
gene id: 351607:ACEL_RS05200
uniprot id: A0LTM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

351607:ACEL RS03670
gene id: 351607:ACEL_RS03670
uniprot id: A0LSS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

351607:ACEL RS04940
gene id: 351607:ACEL_RS04940
uniprot id: A0LTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

351607:ACEL RS10755
gene id: 351607:ACEL_RS10755
uniprot id: A0LWN7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

351607:ACEL RS03180
gene id: 351607:ACEL_RS03180
uniprot id: A0LSI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

351607:ACEL RS03085
gene id: 351607:ACEL_RS03085
uniprot id: A0LSG6
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

351607:ACEL RS03655
gene id: 351607:ACEL_RS03655
uniprot id: A0LSS4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.