349521:HCH RS31560
gene id: 349521:HCH_RS31560
uniprot id: Q2S6W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

349521:HCH RS22090
gene id: 349521:HCH_RS22090
uniprot id: Q2SCL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

349521:HCH RS12730
gene id: 349521:HCH_RS12730
uniprot id: Q2SIC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

349521:HCH RS26410
gene id: 349521:HCH_RS26410
uniprot id: Q2S9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

349521:HCH RS04375
gene id: 349521:HCH_RS04375
uniprot id: Q2SNC2
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

349521:HCH RS12415
gene id: 349521:HCH_RS12415
uniprot id: Q2SIJ3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

349521:HCH RS22080
gene id: 349521:HCH_RS22080
uniprot id: Q2SCL4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

349521:HCH RS10880
gene id: 349521:HCH_RS10880
uniprot id: Q2SJG5
names: Similarity
messages: Belongs to the asparagine synthetase family.

349521:HCH RS04500
gene id: 349521:HCH_RS04500
uniprot id: Q2SN93
names: Similarity
messages: Belongs to the group II decarboxylase family.

349521:HCH RS31995
gene id: 349521:HCH_RS31995
uniprot id: Q2SQI1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

349521:HCH RS26975
gene id: 349521:HCH_RS26975
uniprot id: Q2S9M8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

349521:HCH RS23615
gene id: 349521:HCH_RS23615
uniprot id: Q2SBP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
messages: Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
messages: Cytoplasm
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS12830
gene id: 349521:HCH_RS12830
uniprot id: Q2SIA2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS28075
gene id: 349521:HCH_RS28075
uniprot id: Q2S8Z3
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

349521:HCH RS04535
gene id: 349521:HCH_RS04535
uniprot id: Q2SN86
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

349521:HCH RS27865
gene id: 349521:HCH_RS27865
uniprot id: Q2S931
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

349521:HCH RS26145
gene id: 349521:HCH_RS26145
uniprot id: Q2SA43
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS11375
gene id: 349521:HCH_RS11375
uniprot id: Q2SJ60
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

349521:HCH RS07230
gene id: 349521:HCH_RS07230
uniprot id: Q2SLM3
names: Similarity
messages: Belongs to the heat shock protein 90 family.

349521:HCH RS22050
gene id: 349521:HCH_RS22050
uniprot id: Q2SCM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

349521:HCH RS26495
gene id: 349521:HCH_RS26495
uniprot id: Q2S9X3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

349521:HCH RS27040
gene id: 349521:HCH_RS27040
uniprot id: Q2S9L4
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

349521:HCH RS02115
gene id: 349521:HCH_RS02115
uniprot id: Q2SPQ1
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

349521:HCH RS30515
gene id: 349521:HCH_RS30515
uniprot id: Q2S7I6
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

349521:HCH RS23455
gene id: 349521:HCH_RS23455
uniprot id: Q2SBS3
names: Similarity
messages: Belongs to the peptidase S16 family.

349521:HCH RS25955
gene id: 349521:HCH_RS25955
uniprot id: Q2SA85
names: Subcellular Location Annotation
messages: Secreted

349521:HCH RS05030
gene id: 349521:HCH_RS05030
uniprot id: Q2SMY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS06350
gene id: 349521:HCH_RS06350
uniprot id: Q2SM50
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

349521:HCH RS22295
gene id: 349521:HCH_RS22295
uniprot id: Q2SCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

349521:HCH RS20710
gene id: 349521:HCH_RS20710
uniprot id: Q2SDF5
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS06115
gene id: 349521:HCH_RS06115
uniprot id: Q2SMA2
names: Similarity
messages: Belongs to the OsmC/Ohr family.

349521:HCH RS21170
gene id: 349521:HCH_RS21170
uniprot id: Q2SD54
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

349521:HCH RS05910
gene id: 349521:HCH_RS05910
uniprot id: Q2SME2
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS05450
gene id: 349521:HCH_RS05450
uniprot id: Q2SMN7
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

349521:HCH RS08650
gene id: 349521:HCH_RS08650
uniprot id: Q2SKT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

349521:HCH RS04235
gene id: 349521:HCH_RS04235
uniprot id: Q2SNF0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

349521:HCH RS06085
gene id: 349521:HCH_RS06085
uniprot id: Q2SMA9
names: Similarity
messages: Belongs to the peptidase S41A family.

349521:HCH RS08260
gene id: 349521:HCH_RS08260
uniprot id: Q2SL11
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

349521:HCH RS11815
gene id: 349521:HCH_RS11815
uniprot id: Q2SIX4
names: Similarity
messages: Belongs to the TlyA family.

349521:HCH RS31260
gene id: 349521:HCH_RS31260
uniprot id: Q2S729
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

349521:HCH RS11050
gene id: 349521:HCH_RS11050
uniprot id: Q2SJD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

349521:HCH RS22410
gene id: 349521:HCH_RS22410
uniprot id: Q2SCE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

349521:HCH RS10975
gene id: 349521:HCH_RS10975
uniprot id: Q2SJE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS25105
gene id: 349521:HCH_RS25105
uniprot id: Q2SAS0
names: Similarity
messages: Belongs to the YciI family.

349521:HCH RS03365
gene id: 349521:HCH_RS03365
uniprot id: Q2SNY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS22370
gene id: 349521:HCH_RS22370
uniprot id: Q2SCF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

349521:HCH RS11135
gene id: 349521:HCH_RS11135
uniprot id: Q2SJB1
names: Similarity
messages: Belongs to the ModE family.

349521:HCH RS29340
gene id: 349521:HCH_RS29340
uniprot id: Q2S880
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

349521:HCH RS08450
gene id: 349521:HCH_RS08450
uniprot id: Q2SKX0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

349521:HCH RS10655
gene id: 349521:HCH_RS10655
uniprot id: Q2SJL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

349521:HCH RS24150
gene id: 349521:HCH_RS24150
uniprot id: Q2SBC7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

349521:HCH RS20020
gene id: 349521:HCH_RS20020
uniprot id: Q2SDU3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

349521:HCH RS26810
gene id: 349521:HCH_RS26810
uniprot id: Q2S9R2
names: Function
names: Subunit
messages: Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
messages: Monomer in both c-di-GMP-bound and free forms.

349521:HCH RS10065
gene id: 349521:HCH_RS10065
uniprot id: Q2SJY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS13885
gene id: 349521:HCH_RS13885
uniprot id: Q2SHM4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. PhnX family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Involved in phosphonate degradation.

349521:HCH RS24250
gene id: 349521:HCH_RS24250
uniprot id: Q2SBA6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

349521:HCH RS00860
gene id: 349521:HCH_RS00860
uniprot id: Q2SQG9
names: Similarity
messages: Belongs to the SUI1 family.

349521:HCH RS26615
gene id: 349521:HCH_RS26615
uniprot id: Q2S9V3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

349521:HCH RS23415
gene id: 349521:HCH_RS23415
uniprot id: Q2SBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

349521:HCH RS11110
gene id: 349521:HCH_RS11110
uniprot id: Q2SJB7
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

349521:HCH RS21655
gene id: 349521:HCH_RS21655
uniprot id: Q2SCV4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

349521:HCH RS22325
gene id: 349521:HCH_RS22325
uniprot id: Q2SCG4
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

349521:HCH RS28565
gene id: 349521:HCH_RS28565
uniprot id: Q2SAN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

349521:HCH RS28680
gene id: 349521:HCH_RS28680
uniprot id: Q2S8M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

349521:HCH RS12210
gene id: 349521:HCH_RS12210
uniprot id: Q2SIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

349521:HCH RS26305
gene id: 349521:HCH_RS26305
uniprot id: Q2SA11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

349521:HCH RS11440
gene id: 349521:HCH_RS11440
uniprot id: Q2SJ45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

349521:HCH RS08585
gene id: 349521:HCH_RS08585
uniprot id: Q2SKU6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

349521:HCH RS32125
gene id: 349521:HCH_RS32125
uniprot id: Q2SN13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

349521:HCH RS27930
gene id: 349521:HCH_RS27930
uniprot id: Q2S918
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

349521:HCH RS27870
gene id: 349521:HCH_RS27870
uniprot id: Q2S930
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

349521:HCH RS26310
gene id: 349521:HCH_RS26310
uniprot id: Q2SA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

349521:HCH RS25040
gene id: 349521:HCH_RS25040
uniprot id: Q2SAT6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

349521:HCH RS27535
gene id: 349521:HCH_RS27535
uniprot id: Q2S9A4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS28175
gene id: 349521:HCH_RS28175
uniprot id: Q2S8X7
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

349521:HCH RS10465
gene id: 349521:HCH_RS10465
uniprot id: Q2SJQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS19895
gene id: 349521:HCH_RS19895
uniprot id: Q2SDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

349521:HCH RS23705
gene id: 349521:HCH_RS23705
uniprot id: Q2SBM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

349521:HCH RS03610
gene id: 349521:HCH_RS03610
uniprot id: Q2SNT1
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

349521:HCH RS13580
gene id: 349521:HCH_RS13580
uniprot id: Q2SHT9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

349521:HCH RS22405
gene id: 349521:HCH_RS22405
uniprot id: Q2SCE8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

349521:HCH RS01480
gene id: 349521:HCH_RS01480
uniprot id: Q2SQ37
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS21875
gene id: 349521:HCH_RS21875
uniprot id: Q2SCQ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS07425
gene id: 349521:HCH_RS07425
uniprot id: Q2SLI0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

349521:HCH RS26330
gene id: 349521:HCH_RS26330
uniprot id: Q2SA06
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

349521:HCH RS19305
gene id: 349521:HCH_RS19305
uniprot id: Q2SE96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

349521:HCH RS31940
gene id: 349521:HCH_RS31940
uniprot id: Q2S6N2
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

349521:HCH RS28965
gene id: 349521:HCH_RS28965
uniprot id: Q2S8G5
names: Similarity
messages: Belongs to the GST superfamily.

349521:HCH RS18175
gene id: 349521:HCH_RS18175
uniprot id: Q2SEZ0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

349521:HCH RS21275
gene id: 349521:HCH_RS21275
uniprot id: Q2SD34
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

349521:HCH RS02395
gene id: 349521:HCH_RS02395
uniprot id: Q2SPJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

349521:HCH RS28065
gene id: 349521:HCH_RS28065
uniprot id: Q2S8Z5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS24270
gene id: 349521:HCH_RS24270
uniprot id: Q2SBA2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

349521:HCH RS24690
gene id: 349521:HCH_RS24690
uniprot id: Q2SB12
names: Similarity
messages: Belongs to the peptidase S45 family.

349521:HCH RS26450
gene id: 349521:HCH_RS26450
uniprot id: Q2S9Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

349521:HCH RS09840
gene id: 349521:HCH_RS09840
uniprot id: Q2SK33
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

349521:HCH RS08440
gene id: 349521:HCH_RS08440
uniprot id: Q2SKX2
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

349521:HCH RS26820
gene id: 349521:HCH_RS26820
uniprot id: Q2S9R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS26105
gene id: 349521:HCH_RS26105
uniprot id: Q2SA51
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.

349521:HCH RS08730
gene id: 349521:HCH_RS08730
uniprot id: Q2SKR5
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

349521:HCH RS27935
gene id: 349521:HCH_RS27935
uniprot id: Q2S917
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

349521:HCH RS09720
gene id: 349521:HCH_RS09720
uniprot id: Q2SK56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

349521:HCH RS08160
gene id: 349521:HCH_RS08160
uniprot id: Q2SL31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

349521:HCH RS28910
gene id: 349521:HCH_RS28910
uniprot id: Q2S8H6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS28895
gene id: 349521:HCH_RS28895
uniprot id: Q2S8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS10885
gene id: 349521:HCH_RS10885
uniprot id: Q2SJG4
names: Similarity
messages: Belongs to the asparagine synthetase family.

349521:HCH RS12640
gene id: 349521:HCH_RS12640
uniprot id: Q2SIE7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

349521:HCH RS05220
gene id: 349521:HCH_RS05220
uniprot id: Q2SMT8
names: Similarity
messages: Belongs to the TPP enzyme family.

349521:HCH RS01180
gene id: 349521:HCH_RS01180
uniprot id: Q2SQA0
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS30840
gene id: 349521:HCH_RS30840
uniprot id: Q2S7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS23215
gene id: 349521:HCH_RS23215
uniprot id: Q2SBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

349521:HCH RS14665
gene id: 349521:HCH_RS14665
uniprot id: Q2SH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

349521:HCH RS13830
gene id: 349521:HCH_RS13830
uniprot id: Q2SHN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

349521:HCH RS06335
gene id: 349521:HCH_RS06335
uniprot id: Q2SM53
names: Similarity
messages: Belongs to the SufE family.

349521:HCH RS23225
gene id: 349521:HCH_RS23225
uniprot id: Q2SBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

349521:HCH RS27840
gene id: 349521:HCH_RS27840
uniprot id: Q2S937
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

349521:HCH RS02920
gene id: 349521:HCH_RS02920
uniprot id: Q2SP82
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS11085
gene id: 349521:HCH_RS11085
uniprot id: Q2SJC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

349521:HCH RS23700
gene id: 349521:HCH_RS23700
uniprot id: Q2SBM3
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

349521:HCH RS14130
gene id: 349521:HCH_RS14130
uniprot id: Q2SHH2
names: Function
names: Similarity
messages: Belongs to the CsgG family.
messages: May be involved in the biogenesis of curli organelles.

349521:HCH RS14865
gene id: 349521:HCH_RS14865
uniprot id: Q2SH09
names: Similarity
messages: Belongs to the SIP oxidoreductase family.

349521:HCH RS26025
gene id: 349521:HCH_RS26025
uniprot id: Q2SA69
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

349521:HCH RS07810
gene id: 349521:HCH_RS07810
uniprot id: Q2SLA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

349521:HCH RS31405
gene id: 349521:HCH_RS31405
uniprot id: Q2S6Z8
names: Similarity
messages: Belongs to the UPF0178 family.

349521:HCH RS09760
gene id: 349521:HCH_RS09760
uniprot id: Q2SK47
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

349521:HCH RS14660
gene id: 349521:HCH_RS14660
uniprot id: Q2SH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

349521:HCH RS08640
gene id: 349521:HCH_RS08640
uniprot id: Q2SKT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

349521:HCH RS28665
gene id: 349521:HCH_RS28665
uniprot id: Q2S8M3
names: Similarity
messages: Belongs to the YggT family.

349521:HCH RS19535
gene id: 349521:HCH_RS19535
uniprot id: Q2SE47
names: Similarity
messages: Belongs to the type III secretion exporter family.

349521:HCH RS08230
gene id: 349521:HCH_RS08230
uniprot id: Q2SL17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

349521:HCH RS04880
gene id: 349521:HCH_RS04880
uniprot id: Q2SN12
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

349521:HCH RS19950
gene id: 349521:HCH_RS19950
uniprot id: Q2SDV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS16620
gene id: 349521:HCH_RS16620
uniprot id: Q2SFY0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS09825
gene id: 349521:HCH_RS09825
uniprot id: Q2SK37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

349521:HCH RS05500
gene id: 349521:HCH_RS05500
uniprot id: Q2SMM7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

349521:HCH RS23570
gene id: 349521:HCH_RS23570
uniprot id: Q2SBQ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS08110
gene id: 349521:HCH_RS08110
uniprot id: Q2SL41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

349521:HCH RS35050
gene id: 349521:HCH_RS35050
uniprot id: Q2SCW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

349521:HCH RS20040
gene id: 349521:HCH_RS20040
uniprot id: Q2SDT9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

349521:HCH RS28380
gene id: 349521:HCH_RS28380
uniprot id: Q2S8T3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS30310
gene id: 349521:HCH_RS30310
uniprot id: Q2S7M8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS29635
gene id: 349521:HCH_RS29635
uniprot id: Q2S817
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS10200
gene id: 349521:HCH_RS10200
uniprot id: Q2SJW1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

349521:HCH RS28205
gene id: 349521:HCH_RS28205
uniprot id: Q2S8X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

349521:HCH RS07840
gene id: 349521:HCH_RS07840
uniprot id: Q2SL96
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

349521:HCH RS27750
gene id: 349521:HCH_RS27750
uniprot id: Q2S957
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

349521:HCH RS27770
gene id: 349521:HCH_RS27770
uniprot id: Q2S953
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS10435
gene id: 349521:HCH_RS10435
uniprot id: Q2SJR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

349521:HCH RS08840
gene id: 349521:HCH_RS08840
uniprot id: Q2SKP1
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

349521:HCH RS13990
gene id: 349521:HCH_RS13990
uniprot id: Q2SHK1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS07985
gene id: 349521:HCH_RS07985
uniprot id: Q2SL66
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

349521:HCH RS16800
gene id: 349521:HCH_RS16800
uniprot id: Q2SFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

349521:HCH RS02210
gene id: 349521:HCH_RS02210
uniprot id: Q2SPN4
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

349521:HCH RS13155
gene id: 349521:HCH_RS13155
uniprot id: Q2SI34
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS16775
gene id: 349521:HCH_RS16775
uniprot id: Q2SFU4
names: Similarity
messages: Belongs to the UPF0386 family.

349521:HCH RS08900
gene id: 349521:HCH_RS08900
uniprot id: Q2SKM8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS15660
gene id: 349521:HCH_RS15660
uniprot id: Q2SGJ3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS15205
gene id: 349521:HCH_RS15205
uniprot id: Q2SGT6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NosZ family.
messages: Binds 2 calcium ions per subunit.
messages: Binds 6 Cu cations per subunit. Each subunit contains 2 copper centers; Cu(A) (binuclear) and Cu(Z) (tetranuclear). Cu(Z) is thought to be the site of nitrous oxide reduction.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

349521:HCH RS09725
gene id: 349521:HCH_RS09725
uniprot id: Q2SK54
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

349521:HCH RS03135
gene id: 349521:HCH_RS03135
uniprot id: Q2SP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

349521:HCH RS03860
gene id: 349521:HCH_RS03860
uniprot id: Q2SNN1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Binds 2 potassium ions per subunit.
messages: Dimer of dimers.
messages: Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS28650
gene id: 349521:HCH_RS28650
uniprot id: Q2S8M6
names: Similarity
messages: Belongs to the GSP E family.

349521:HCH RS11275
gene id: 349521:HCH_RS11275
uniprot id: Q2SJ80
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS11830
gene id: 349521:HCH_RS11830
uniprot id: Q2SIX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

349521:HCH RS14930
gene id: 349521:HCH_RS14930
uniprot id: Q2SGZ6
names: Similarity
messages: Belongs to the GST superfamily.

349521:HCH RS25710
gene id: 349521:HCH_RS25710
uniprot id: Q2SAE0
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS19750
gene id: 349521:HCH_RS19750
uniprot id: Q2SDZ8
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

349521:HCH RS02000
gene id: 349521:HCH_RS02000
uniprot id: Q2SPS5
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

349521:HCH RS22005
gene id: 349521:HCH_RS22005
uniprot id: Q2SCM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

349521:HCH RS06465
gene id: 349521:HCH_RS06465
uniprot id: Q2SM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

349521:HCH RS28475
gene id: 349521:HCH_RS28475
uniprot id: Q2S8R4
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

349521:HCH RS14225
gene id: 349521:HCH_RS14225
uniprot id: Q2SHE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

349521:HCH RS11080
gene id: 349521:HCH_RS11080
uniprot id: Q2SJC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

349521:HCH RS14670
gene id: 349521:HCH_RS14670
uniprot id: Q2SH51
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

349521:HCH RS12890
gene id: 349521:HCH_RS12890
uniprot id: Q2SI92
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

349521:HCH RS11200
gene id: 349521:HCH_RS11200
uniprot id: Q2SJ96
names: Similarity
messages: Belongs to the FGGY kinase family.

349521:HCH RS15460
gene id: 349521:HCH_RS15460
uniprot id: Q2SGN6
names: Similarity
messages: Belongs to the thioesterase family.

349521:HCH RS26460
gene id: 349521:HCH_RS26460
uniprot id: Q2S9Y0
names: Similarity
messages: Belongs to the UPF0102 family.

349521:HCH RS26260
gene id: 349521:HCH_RS26260
uniprot id: Q2SA20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

349521:HCH RS23295
gene id: 349521:HCH_RS23295
uniprot id: Q2SBV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

349521:HCH RS00030
gene id: 349521:HCH_RS00030
uniprot id: Q2SQZ3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

349521:HCH RS21495
gene id: 349521:HCH_RS21495
uniprot id: Q2SCY9
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

349521:HCH RS11445
gene id: 349521:HCH_RS11445
uniprot id: Q2SJ44
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

349521:HCH RS10665
gene id: 349521:HCH_RS10665
uniprot id: Q2SJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

349521:HCH RS20105
gene id: 349521:HCH_RS20105
uniprot id: Q2SDS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS17225
gene id: 349521:HCH_RS17225
uniprot id: Q2SFJ8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS12720
gene id: 349521:HCH_RS12720
uniprot id: Q2SIC9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

349521:HCH RS16555
gene id: 349521:HCH_RS16555
uniprot id: Q2SFZ2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

349521:HCH RS27455
gene id: 349521:HCH_RS27455
uniprot id: Q2S9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

349521:HCH RS34375
gene id: 349521:HCH_RS34375
uniprot id: Q2SQT0
names: Similarity
messages: Belongs to the HypD family.

349521:HCH RS26340
gene id: 349521:HCH_RS26340
uniprot id: Q2SA04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

349521:HCH RS04910
gene id: 349521:HCH_RS04910
uniprot id: Q2SN06
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

349521:HCH RS15890
gene id: 349521:HCH_RS15890
uniprot id: Q2SGE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS16020
gene id: 349521:HCH_RS16020
uniprot id: Q2SGA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS03510
gene id: 349521:HCH_RS03510
uniprot id: Q2SNV2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

349521:HCH RS29000
gene id: 349521:HCH_RS29000
uniprot id: Q2S8F7
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

349521:HCH RS21295
gene id: 349521:HCH_RS21295
uniprot id: Q2SD30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS28245
gene id: 349521:HCH_RS28245
uniprot id: Q2S8W2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

349521:HCH RS26765
gene id: 349521:HCH_RS26765
uniprot id: Q2S9S1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

349521:HCH RS21130
gene id: 349521:HCH_RS21130
uniprot id: Q2SD62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

349521:HCH RS20715
gene id: 349521:HCH_RS20715
uniprot id: Q2SDF4
names: Similarity
messages: Belongs to the UPF0234 family.

349521:HCH RS17690
gene id: 349521:HCH_RS17690
uniprot id: Q2SF97
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

349521:HCH RS06755
gene id: 349521:HCH_RS06755
uniprot id: Q2SLW9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS18210
gene id: 349521:HCH_RS18210
uniprot id: Q2SEY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

349521:HCH RS22420
gene id: 349521:HCH_RS22420
uniprot id: Q2SCE5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

349521:HCH RS04590
gene id: 349521:HCH_RS04590
uniprot id: Q2SN73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

349521:HCH RS05290
gene id: 349521:HCH_RS05290
uniprot id: Q2SAN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

349521:HCH RS23890
gene id: 349521:HCH_RS23890
uniprot id: Q2SBI2
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

349521:HCH RS08770
gene id: 349521:HCH_RS08770
uniprot id: Q2SKQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349521:HCH RS01290
gene id: 349521:HCH_RS01290
uniprot id: Q2SQ77
names: Similarity
messages: Belongs to the thioredoxin family.

349521:HCH RS18065
gene id: 349521:HCH_RS18065
uniprot id: Q2SF14
names: Similarity
messages: Belongs to the YkuD family.

349521:HCH RS03385
gene id: 349521:HCH_RS03385
uniprot id: Q2SNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS21970
gene id: 349521:HCH_RS21970
uniprot id: Q2SCN4
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

349521:HCH RS05485
gene id: 349521:HCH_RS05485
uniprot id: Q2SMN0
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

349521:HCH RS22820
gene id: 349521:HCH_RS22820
uniprot id: Q2SC63
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS11350
gene id: 349521:HCH_RS11350
uniprot id: Q2SJ65
names: Similarity
messages: Belongs to the heat shock protein 70 family.

349521:HCH RS12325
gene id: 349521:HCH_RS12325
uniprot id: Q2SIL2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS00975
gene id: 349521:HCH_RS00975
uniprot id: Q2SQE6
names: Similarity
messages: Belongs to the NodU/CmcH family.

349521:HCH RS13705
gene id: 349521:HCH_RS13705
uniprot id: Q2SHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

349521:HCH RS01625
gene id: 349521:HCH_RS01625
uniprot id: Q2SQ03
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS05635
gene id: 349521:HCH_RS05635
uniprot id: Q2SMK0
names: Similarity
messages: Belongs to the leucine-binding protein family.

349521:HCH RS24255
gene id: 349521:HCH_RS24255
uniprot id: Q2SBA5
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

349521:HCH RS28000
gene id: 349521:HCH_RS28000
uniprot id: Q2S904
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

349521:HCH RS06130
gene id: 349521:HCH_RS06130
uniprot id: Q2SM98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS01245
gene id: 349521:HCH_RS01245
uniprot id: Q2SQ86
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349521:HCH RS06635
gene id: 349521:HCH_RS06635
uniprot id: Q2SLZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS29595
gene id: 349521:HCH_RS29595
uniprot id: Q2S826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS14075
gene id: 349521:HCH_RS14075
uniprot id: Q2SHI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS00985
gene id: 349521:HCH_RS00985
uniprot id: Q2SQE3
names: Similarity
messages: Belongs to the pirin family.

349521:HCH RS27885
gene id: 349521:HCH_RS27885
uniprot id: Q2S927
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

349521:HCH RS03620
gene id: 349521:HCH_RS03620
uniprot id: Q2SNS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

349521:HCH RS31545
gene id: 349521:HCH_RS31545
uniprot id: Q2S6W7
names: Similarity
messages: Belongs to the NAPRTase family.

349521:HCH RS20520
gene id: 349521:HCH_RS20520
uniprot id: Q2SDI9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS24110
gene id: 349521:HCH_RS24110
uniprot id: Q2SBD5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

349521:HCH RS12255
gene id: 349521:HCH_RS12255
uniprot id: Q2SIM7
names: Similarity
messages: Belongs to the citrate synthase family.

349521:HCH RS07705
gene id: 349521:HCH_RS07705
uniprot id: Q2SLC1
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

349521:HCH RS03520
gene id: 349521:HCH_RS03520
uniprot id: Q2SNV0
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

349521:HCH RS22665
gene id: 349521:HCH_RS22665
uniprot id: Q2SC97
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS11370
gene id: 349521:HCH_RS11370
uniprot id: Q2SJ61
names: Similarity
messages: Belongs to the universal stress protein A family.

349521:HCH RS10470
gene id: 349521:HCH_RS10470
uniprot id: Q2SJQ2
names: Similarity
messages: Belongs to the class-A beta-lactamase family.

349521:HCH RS26275
gene id: 349521:HCH_RS26275
uniprot id: Q2SA17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS04975
gene id: 349521:HCH_RS04975
uniprot id: Q2SMZ2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS09900
gene id: 349521:HCH_RS09900
uniprot id: Q2SK22
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

349521:HCH RS13590
gene id: 349521:HCH_RS13590
uniprot id: Q2SHT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

349521:HCH RS11145
gene id: 349521:HCH_RS11145
uniprot id: Q2SJA9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS20920
gene id: 349521:HCH_RS20920
uniprot id: Q2SDB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

349521:HCH RS26530
gene id: 349521:HCH_RS26530
uniprot id: Q2S9W6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

349521:HCH RS08220
gene id: 349521:HCH_RS08220
uniprot id: Q2SL19
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

349521:HCH RS31915
gene id: 349521:HCH_RS31915
uniprot id: Q2S6N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

349521:HCH RS26710
gene id: 349521:HCH_RS26710
uniprot id: Q2S9T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

349521:HCH RS27760
gene id: 349521:HCH_RS27760
uniprot id: Q2S955
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS11925
gene id: 349521:HCH_RS11925
uniprot id: Q2SIV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

349521:HCH RS15390
gene id: 349521:HCH_RS15390
uniprot id: Q2SGQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS04600
gene id: 349521:HCH_RS04600
uniprot id: Q2SN71
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

349521:HCH RS06385
gene id: 349521:HCH_RS06385
uniprot id: Q2SM41
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

349521:HCH RS09000
gene id: 349521:HCH_RS09000
uniprot id: Q2SKK5
names: Similarity
messages: Belongs to the UPF0145 family.

349521:HCH RS20050
gene id: 349521:HCH_RS20050
uniprot id: Q2SDT7
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

349521:HCH RS09350
gene id: 349521:HCH_RS09350
uniprot id: Q2SKD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

349521:HCH RS05040
gene id: 349521:HCH_RS05040
uniprot id: Q2SMX8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS14650
gene id: 349521:HCH_RS14650
uniprot id: Q2SH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

349521:HCH RS05640
gene id: 349521:HCH_RS05640
uniprot id: Q2SMJ9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

349521:HCH RS02370
gene id: 349521:HCH_RS02370
uniprot id: Q2SPJ9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS29095
gene id: 349521:HCH_RS29095
uniprot id: Q2S8D3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

349521:HCH RS19815
gene id: 349521:HCH_RS19815
uniprot id: Q2SDY3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS26285
gene id: 349521:HCH_RS26285
uniprot id: Q2SA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS25085
gene id: 349521:HCH_RS25085
uniprot id: Q2SAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

349521:HCH RS04660
gene id: 349521:HCH_RS04660
uniprot id: Q2SN59
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

349521:HCH RS27605
gene id: 349521:HCH_RS27605
uniprot id: Q2S988
names: Similarity
messages: Belongs to the phosphoribulokinase family.

349521:HCH RS26375
gene id: 349521:HCH_RS26375
uniprot id: Q2S9Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

349521:HCH RS11535
gene id: 349521:HCH_RS11535
uniprot id: Q2SJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

349521:HCH RS07825
gene id: 349521:HCH_RS07825
uniprot id: Q2SLA0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

349521:HCH RS26350
gene id: 349521:HCH_RS26350
uniprot id: Q2SA02
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

349521:HCH RS06860
gene id: 349521:HCH_RS06860
uniprot id: Q2SLU7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

349521:HCH RS07890
gene id: 349521:HCH_RS07890
uniprot id: Q2SL86
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

349521:HCH RS23420
gene id: 349521:HCH_RS23420
uniprot id: Q2SBT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

349521:HCH RS30255
gene id: 349521:HCH_RS30255
uniprot id: Q2S7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS02090
gene id: 349521:HCH_RS02090
uniprot id: Q2SPQ6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS27035
gene id: 349521:HCH_RS27035
uniprot id: Q2S9L5
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

349521:HCH RS12665
gene id: 349521:HCH_RS12665
uniprot id: Q2SIE2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS17650
gene id: 349521:HCH_RS17650
uniprot id: Q2SFA7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

349521:HCH RS08145
gene id: 349521:HCH_RS08145
uniprot id: Q2SL34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

349521:HCH RS04850
gene id: 349521:HCH_RS04850
uniprot id: Q2SN18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

349521:HCH RS14685
gene id: 349521:HCH_RS14685
uniprot id: Q2SH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

349521:HCH RS17890
gene id: 349521:HCH_RS17890
uniprot id: Q2SF49
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS23960
gene id: 349521:HCH_RS23960
uniprot id: Q2SBG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

349521:HCH RS15100
gene id: 349521:HCH_RS15100
uniprot id: Q2SGV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

349521:HCH RS20640
gene id: 349521:HCH_RS20640
uniprot id: Q2SDG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

349521:HCH RS17110
gene id: 349521:HCH_RS17110
uniprot id: Q2SFM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Fes family.
messages: Cytoplasm

349521:HCH RS30820
gene id: 349521:HCH_RS30820
uniprot id: Q2S7C6
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

349521:HCH RS25960
gene id: 349521:HCH_RS25960
uniprot id: Q2SA84
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS31950
gene id: 349521:HCH_RS31950
uniprot id: Q2S6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

349521:HCH RS30660
gene id: 349521:HCH_RS30660
uniprot id: Q2S7F9
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

349521:HCH RS29215
gene id: 349521:HCH_RS29215
uniprot id: Q2S8A9
names: Similarity
messages: Belongs to the CobH/CbiC family.

349521:HCH RS11230
gene id: 349521:HCH_RS11230
uniprot id: Q2SJ89
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

349521:HCH RS10165
gene id: 349521:HCH_RS10165
uniprot id: Q2SJW8
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
messages: Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS05140
gene id: 349521:HCH_RS05140
uniprot id: Q2SMV8
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

349521:HCH RS26795
gene id: 349521:HCH_RS26795
uniprot id: Q2S9R5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

349521:HCH RS31400
gene id: 349521:HCH_RS31400
uniprot id: Q2S6Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

349521:HCH RS02005
gene id: 349521:HCH_RS02005
uniprot id: Q2SPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

349521:HCH RS20550
gene id: 349521:HCH_RS20550
uniprot id: Q2SDI3
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS31445
gene id: 349521:HCH_RS31445
uniprot id: Q2S6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS27905
gene id: 349521:HCH_RS27905
uniprot id: Q2S923
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

349521:HCH RS28010
gene id: 349521:HCH_RS28010
uniprot id: Q2S902
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

349521:HCH RS20035
gene id: 349521:HCH_RS20035
uniprot id: Q2SDU0
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

349521:HCH RS27020
gene id: 349521:HCH_RS27020
uniprot id: Q2S9L8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

349521:HCH RS21635
gene id: 349521:HCH_RS21635
uniprot id: Q2SCV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

349521:HCH RS02570
gene id: 349521:HCH_RS02570
uniprot id: Q2SPF7
names: Similarity
messages: Belongs to the HSP15 family.

349521:HCH RS24645
gene id: 349521:HCH_RS24645
uniprot id: Q2SB23
names: Similarity
messages: Belongs to the carbamate kinase family.

349521:HCH RS09950
gene id: 349521:HCH_RS09950
uniprot id: Q2SK10
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349521:HCH RS05555
gene id: 349521:HCH_RS05555
uniprot id: Q2SML6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

349521:HCH RS05240
gene id: 349521:HCH_RS05240
uniprot id: Q2SMT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
messages: Cell inner membrane
messages: Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.

349521:HCH RS21190
gene id: 349521:HCH_RS21190
uniprot id: Q2SD50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

349521:HCH RS26315
gene id: 349521:HCH_RS26315
uniprot id: Q2SA09
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

349521:HCH RS31935
gene id: 349521:HCH_RS31935
uniprot id: Q2S6N4
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS23085
gene id: 349521:HCH_RS23085
uniprot id: Q2SC02
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS16525
gene id: 349521:HCH_RS16525
uniprot id: Q2SFZ8
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

349521:HCH RS06290
gene id: 349521:HCH_RS06290
uniprot id: Q2SM62
names: Similarity
messages: Belongs to the TPP enzyme family.

349521:HCH RS24095
gene id: 349521:HCH_RS24095
uniprot id: Q2SBD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS21100
gene id: 349521:HCH_RS21100
uniprot id: Q2SD69
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS29840
gene id: 349521:HCH_RS29840
uniprot id: Q2S7X4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS22160
gene id: 349521:HCH_RS22160
uniprot id: Q2SCJ7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

349521:HCH RS09965
gene id: 349521:HCH_RS09965
uniprot id: Q2SK07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

349521:HCH RS22375
gene id: 349521:HCH_RS22375
uniprot id: Q2SCF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349521:HCH RS21220
gene id: 349521:HCH_RS21220
uniprot id: Q2SD45
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

349521:HCH RS03500
gene id: 349521:HCH_RS03500
uniprot id: Q2SNV4
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

349521:HCH RS11015
gene id: 349521:HCH_RS11015
uniprot id: Q2SJD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

349521:HCH RS31165
gene id: 349521:HCH_RS31165
uniprot id: Q2S749
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

349521:HCH RS27700
gene id: 349521:HCH_RS27700
uniprot id: Q2S969
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

349521:HCH RS31530
gene id: 349521:HCH_RS31530
uniprot id: Q2S6X2
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

349521:HCH RS04695
gene id: 349521:HCH_RS04695
uniprot id: Q2SN51
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

349521:HCH RS10825
gene id: 349521:HCH_RS10825
uniprot id: Q2SJH6
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS23305
gene id: 349521:HCH_RS23305
uniprot id: Q2SBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

349521:HCH RS10845
gene id: 349521:HCH_RS10845
uniprot id: Q2SJH2
names: Similarity
messages: Belongs to the NodU/CmcH family.

349521:HCH RS26465
gene id: 349521:HCH_RS26465
uniprot id: Q2S9X9
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

349521:HCH RS10050
gene id: 349521:HCH_RS10050
uniprot id: Q2SJZ2
names: Function
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: Endopeptidase that degrades small peptides of less than 7 kDa, such as glucagon and insulin.

349521:HCH RS26335
gene id: 349521:HCH_RS26335
uniprot id: Q2SA05
names: Similarity
messages: Belongs to the MoaD family.

349521:HCH RS11395
gene id: 349521:HCH_RS11395
uniprot id: Q2SJ55
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

349521:HCH RS30415
gene id: 349521:HCH_RS30415
uniprot id: Q2S7K7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

349521:HCH RS02250
gene id: 349521:HCH_RS02250
uniprot id: Q2SPM6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

349521:HCH RS34280
gene id: 349521:HCH_RS34280
uniprot id: Q2SFV7
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

349521:HCH RS06625
gene id: 349521:HCH_RS06625
uniprot id: Q2SLZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

349521:HCH RS28695
gene id: 349521:HCH_RS28695
uniprot id: Q2S8L7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

349521:HCH RS17605
gene id: 349521:HCH_RS17605
uniprot id: Q2SFB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

349521:HCH RS04325
gene id: 349521:HCH_RS04325
uniprot id: Q2SND1
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

349521:HCH RS05575
gene id: 349521:HCH_RS05575
uniprot id: Q2SML3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

349521:HCH RS06365
gene id: 349521:HCH_RS06365
uniprot id: Q2SM46
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

349521:HCH RS30745
gene id: 349521:HCH_RS30745
uniprot id: Q2S7E2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS29645
gene id: 349521:HCH_RS29645
uniprot id: Q2S815
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS26845
gene id: 349521:HCH_RS26845
uniprot id: Q2S9Q5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS05455
gene id: 349521:HCH_RS05455
uniprot id: Q2SMN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

349521:HCH RS26585
gene id: 349521:HCH_RS26585
uniprot id: Q2S9V9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

349521:HCH RS28925
gene id: 349521:HCH_RS28925
uniprot id: Q2S8H3
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

349521:HCH RS12380
gene id: 349521:HCH_RS12380
uniprot id: Q2SIK1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

349521:HCH RS17855
gene id: 349521:HCH_RS17855
uniprot id: Q2SF57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

349521:HCH RS08310
gene id: 349521:HCH_RS08310
uniprot id: Q2SL01
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

349521:HCH RS05505
gene id: 349521:HCH_RS05505
uniprot id: Q2SMM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

349521:HCH RS02470
gene id: 349521:HCH_RS02470
uniprot id: Q2SPH8
names: Caution
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS35065
gene id: 349521:HCH_RS35065
uniprot id: Q2SAB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

349521:HCH RS26890
gene id: 349521:HCH_RS26890
uniprot id: Q2S9P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

349521:HCH RS31475
gene id: 349521:HCH_RS31475
uniprot id: Q2S6Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

349521:HCH RS10370
gene id: 349521:HCH_RS10370
uniprot id: Q2SJS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CcoP / FixP family.
messages: Binds 2 heme C groups per subunit.
messages: C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
messages: Cell inner membrane
messages: Component of the cbb3-type cytochrome c oxidase.

349521:HCH RS02405
gene id: 349521:HCH_RS02405
uniprot id: Q2SPJ2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

349521:HCH RS08355
gene id: 349521:HCH_RS08355
uniprot id: Q2SKZ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

349521:HCH RS07860
gene id: 349521:HCH_RS07860
uniprot id: Q2SL92
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

349521:HCH RS26885
gene id: 349521:HCH_RS26885
uniprot id: Q2S9P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

349521:HCH RS06920
gene id: 349521:HCH_RS06920
uniprot id: Q2SLT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

349521:HCH RS17370
gene id: 349521:HCH_RS17370
uniprot id: Q2SFG6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

349521:HCH RS03400
gene id: 349521:HCH_RS03400
uniprot id: Q2SNX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

349521:HCH RS08170
gene id: 349521:HCH_RS08170
uniprot id: Q2SL29
names: Subcellular Location Annotation
messages: Cell inner membrane

349521:HCH RS23735
gene id: 349521:HCH_RS23735
uniprot id: Q2SBL6
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

349521:HCH RS08605
gene id: 349521:HCH_RS08605
uniprot id: Q2SKU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

349521:HCH RS11105
gene id: 349521:HCH_RS11105
uniprot id: Q2SJB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

349521:HCH RS22035
gene id: 349521:HCH_RS22035
uniprot id: Q2SCM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

349521:HCH RS04925
gene id: 349521:HCH_RS04925
uniprot id: Q2SN03
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

349521:HCH RS00500
gene id: 349521:HCH_RS00500
uniprot id: Q2SQP6
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.

349521:HCH RS29240
gene id: 349521:HCH_RS29240
uniprot id: Q2S8A4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

349521:HCH RS24030
gene id: 349521:HCH_RS24030
uniprot id: Q2SBF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

349521:HCH RS20475
gene id: 349521:HCH_RS20475
uniprot id: Q2SDJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

349521:HCH RS28165
gene id: 349521:HCH_RS28165
uniprot id: Q2S8X9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS03420
gene id: 349521:HCH_RS03420
uniprot id: Q2SNX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

349521:HCH RS26370
gene id: 349521:HCH_RS26370
uniprot id: Q2S9Z8
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

349521:HCH RS00990
gene id: 349521:HCH_RS00990
uniprot id: Q2SQE2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS26725
gene id: 349521:HCH_RS26725
uniprot id: Q2S9T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

349521:HCH RS00250
gene id: 349521:HCH_RS00250
uniprot id: Q2SQU8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

349521:HCH RS10170
gene id: 349521:HCH_RS10170
uniprot id: Q2SJW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS02230
gene id: 349521:HCH_RS02230
uniprot id: Q2SPN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS02915
gene id: 349521:HCH_RS02915
uniprot id: Q2SP83
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS13410
gene id: 349521:HCH_RS13410
uniprot id: Q2SHX7
names: Similarity
messages: Belongs to the serine/threonine dehydratase family. DsdA subfamily.

349521:HCH RS29040
gene id: 349521:HCH_RS29040
uniprot id: Q2S8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS11225
gene id: 349521:HCH_RS11225
uniprot id: Q2SJ90
names: Similarity
messages: Belongs to the peptidase M4 family.

349521:HCH RS22320
gene id: 349521:HCH_RS22320
uniprot id: Q2SCG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS27460
gene id: 349521:HCH_RS27460
uniprot id: Q2S9B9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS03985
gene id: 349521:HCH_RS03985
uniprot id: Q2SNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

349521:HCH RS04005
gene id: 349521:HCH_RS04005
uniprot id: Q2SNJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

349521:HCH RS12020
gene id: 349521:HCH_RS12020
uniprot id: Q2SIS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS20905
gene id: 349521:HCH_RS20905
uniprot id: Q2SDB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349521:HCH RS28660
gene id: 349521:HCH_RS28660
uniprot id: Q2S8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

349521:HCH RS08020
gene id: 349521:HCH_RS08020
uniprot id: Q2SL59
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

349521:HCH RS11000
gene id: 349521:HCH_RS11000
uniprot id: Q2SJE1
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS22805
gene id: 349521:HCH_RS22805
uniprot id: Q2SC66
names: Similarity
messages: Belongs to the fatty acyl-CoA reductase family.

349521:HCH RS12470
gene id: 349521:HCH_RS12470
uniprot id: Q2SII2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

349521:HCH RS23930
gene id: 349521:HCH_RS23930
uniprot id: Q2SBH4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

349521:HCH RS24655
gene id: 349521:HCH_RS24655
uniprot id: Q2SB21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

349521:HCH RS05975
gene id: 349521:HCH_RS05975
uniprot id: Q2SMC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

349521:HCH RS09635
gene id: 349521:HCH_RS09635
uniprot id: Q2SK74
names: Similarity
messages: Belongs to the peptidase M16 family.

349521:HCH RS01325
gene id: 349521:HCH_RS01325
uniprot id: Q2SQ70
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

349521:HCH RS23590
gene id: 349521:HCH_RS23590
uniprot id: Q2SBP7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

349521:HCH RS04620
gene id: 349521:HCH_RS04620
uniprot id: Q2SN67
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

349521:HCH RS09870
gene id: 349521:HCH_RS09870
uniprot id: Q2SK28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS23545
gene id: 349521:HCH_RS23545
uniprot id: Q2SBQ7
names: Similarity
messages: Belongs to the Skp family.

349521:HCH RS05615
gene id: 349521:HCH_RS05615
uniprot id: Q2SMK4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

349521:HCH RS03230
gene id: 349521:HCH_RS03230
uniprot id: Q2SP12
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS06715
gene id: 349521:HCH_RS06715
uniprot id: Q2SLX7
names: Similarity
messages: Belongs to the 2-oxoadipate dioxygenase/decarboxylase family.

349521:HCH RS20580
gene id: 349521:HCH_RS20580
uniprot id: Q2SDH7
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

349521:HCH RS27350
gene id: 349521:HCH_RS27350
uniprot id: Q2S9E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS09780
gene id: 349521:HCH_RS09780
uniprot id: Q2SK43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

349521:HCH RS26120
gene id: 349521:HCH_RS26120
uniprot id: Q2SA48
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

349521:HCH RS09325
gene id: 349521:HCH_RS09325
uniprot id: Q2SKD5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS02580
gene id: 349521:HCH_RS02580
uniprot id: Q2SPF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

349521:HCH RS30015
gene id: 349521:HCH_RS30015
uniprot id: Q2S7T8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

349521:HCH RS26590
gene id: 349521:HCH_RS26590
uniprot id: Q2S9V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

349521:HCH RS05715
gene id: 349521:HCH_RS05715
uniprot id: Q2SMI4
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

349521:HCH RS12010
gene id: 349521:HCH_RS12010
uniprot id: Q2SIT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the helicase family. DinG subfamily. Type 1 sub-subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA-dependent ATPase and 5'-3' DNA helicase.

349521:HCH RS12170
gene id: 349521:HCH_RS12170
uniprot id: Q2SIP5
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

349521:HCH RS00005
gene id: 349521:HCH_RS00005
uniprot id: Q2SQZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

349521:HCH RS23040
gene id: 349521:HCH_RS23040
uniprot id: Q2SC13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial secretin family. T3SS SctC subfamily.
messages: Cell outer membrane
messages: Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane.
messages: Membrane
messages: The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex.

349521:HCH RS26280
gene id: 349521:HCH_RS26280
uniprot id: Q2SA16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

349521:HCH RS13840
gene id: 349521:HCH_RS13840
uniprot id: Q2SHN3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

349521:HCH RS34370
gene id: 349521:HCH_RS34370
uniprot id: Q2SQT1
names: Similarity
messages: Belongs to the HypE family.

349521:HCH RS29065
gene id: 349521:HCH_RS29065
uniprot id: Q2S8E0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

349521:HCH RS01090
gene id: 349521:HCH_RS01090
uniprot id: Q2SQC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

349521:HCH RS26970
gene id: 349521:HCH_RS26970
uniprot id: Q2S9N0
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

349521:HCH RS22480
gene id: 349521:HCH_RS22480
uniprot id: Q2SCD3
names: Similarity
messages: Belongs to the BolA/IbaG family.

349521:HCH RS08595
gene id: 349521:HCH_RS08595
uniprot id: Q2SKU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

349521:HCH RS31975
gene id: 349521:HCH_RS31975
uniprot id: Q2S6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

349521:HCH RS27410
gene id: 349521:HCH_RS27410
uniprot id: Q2S9D0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

349521:HCH RS30935
gene id: 349521:HCH_RS30935
uniprot id: Q2S7A1
names: Similarity
messages: Belongs to the universal stress protein A family.

349521:HCH RS28115
gene id: 349521:HCH_RS28115
uniprot id: Q2S8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS22825
gene id: 349521:HCH_RS22825
uniprot id: Q2SC62
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

349521:HCH RS02595
gene id: 349521:HCH_RS02595
uniprot id: Q2SPF2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS22060
gene id: 349521:HCH_RS22060
uniprot id: Q2SCL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

349521:HCH RS24210
gene id: 349521:HCH_RS24210
uniprot id: Q2SBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

349521:HCH RS05580
gene id: 349521:HCH_RS05580
uniprot id: Q2SML2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

349521:HCH RS15490
gene id: 349521:HCH_RS15490
uniprot id: Q2SGN0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS05590
gene id: 349521:HCH_RS05590
uniprot id: Q2SML0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

349521:HCH RS04585
gene id: 349521:HCH_RS04585
uniprot id: Q2SN74
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

349521:HCH RS20240
gene id: 349521:HCH_RS20240
uniprot id: Q2SDP4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.

349521:HCH RS24380
gene id: 349521:HCH_RS24380
uniprot id: Q2SB79
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS05340
gene id: 349521:HCH_RS05340
uniprot id: Q2SMQ9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS23190
gene id: 349521:HCH_RS23190
uniprot id: Q2SBX8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

349521:HCH RS06940
gene id: 349521:HCH_RS06940
uniprot id: Q2SLT0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349521:HCH RS22360
gene id: 349521:HCH_RS22360
uniprot id: Q2SCF7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

349521:HCH RS28200
gene id: 349521:HCH_RS28200
uniprot id: Q2S8X2
names: Similarity
messages: Belongs to the SfsA family.

349521:HCH RS09100
gene id: 349521:HCH_RS09100
uniprot id: Q2SKI3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS22980
gene id: 349521:HCH_RS22980
uniprot id: Q2SC29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Membrane

349521:HCH RS10570
gene id: 349521:HCH_RS10570
uniprot id: Q2SJM8
names: Cofactor
messages: Can also use Mn(2+) ion.

349521:HCH RS34215
gene id: 349521:HCH_RS34215
uniprot id: Q2SIZ4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS21245
gene id: 349521:HCH_RS21245
uniprot id: Q2SD40
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

349521:HCH RS15535
gene id: 349521:HCH_RS15535
uniprot id: Q2SGM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS27595
gene id: 349521:HCH_RS27595
uniprot id: Q2S990
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

349521:HCH RS11555
gene id: 349521:HCH_RS11555
uniprot id: Q2SJ22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS28160
gene id: 349521:HCH_RS28160
uniprot id: Q2S8Y0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

349521:HCH RS07645
gene id: 349521:HCH_RS07645
uniprot id: Q2SLD2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS16610
gene id: 349521:HCH_RS16610
uniprot id: Q2SFY2
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

349521:HCH RS26170
gene id: 349521:HCH_RS26170
uniprot id: Q2SA38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

349521:HCH RS11195
gene id: 349521:HCH_RS11195
uniprot id: Q2SJ97
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

349521:HCH RS10660
gene id: 349521:HCH_RS10660
uniprot id: Q2SJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

349521:HCH RS22850
gene id: 349521:HCH_RS22850
uniprot id: Q2SC57
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell inner membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

349521:HCH RS28020
gene id: 349521:HCH_RS28020
uniprot id: Q2S900
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

349521:HCH RS26225
gene id: 349521:HCH_RS26225
uniprot id: Q2SA27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

349521:HCH RS31145
gene id: 349521:HCH_RS31145
uniprot id: Q2S753
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS18570
gene id: 349521:HCH_RS18570
uniprot id: Q2SEQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS31170
gene id: 349521:HCH_RS31170
uniprot id: Q2S748
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS17280
gene id: 349521:HCH_RS17280
uniprot id: Q2SFI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS25790
gene id: 349521:HCH_RS25790
uniprot id: Q2SAC2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS07895
gene id: 349521:HCH_RS07895
uniprot id: Q2SL85
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

349521:HCH RS06120
gene id: 349521:HCH_RS06120
uniprot id: Q2SMA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

349521:HCH RS10935
gene id: 349521:HCH_RS10935
uniprot id: Q2SJF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

349521:HCH RS27875
gene id: 349521:HCH_RS27875
uniprot id: Q2S929
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

349521:HCH RS15675
gene id: 349521:HCH_RS15675
uniprot id: Q2SGJ0
names: Similarity
messages: Belongs to the fabD family.

349521:HCH RS26425
gene id: 349521:HCH_RS26425
uniprot id: Q2S9Y7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS08905
gene id: 349521:HCH_RS08905
uniprot id: Q2SKM7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

349521:HCH RS22085
gene id: 349521:HCH_RS22085
uniprot id: Q2SCL3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

349521:HCH RS06785
gene id: 349521:HCH_RS06785
uniprot id: Q2SLW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

349521:HCH RS17285
gene id: 349521:HCH_RS17285
uniprot id: Q2SFI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349521:HCH RS22265
gene id: 349521:HCH_RS22265
uniprot id: Q2SCH7
names: Similarity
messages: Belongs to the peptidase M18 family.

349521:HCH RS26390
gene id: 349521:HCH_RS26390
uniprot id: Q2S9Z4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

349521:HCH RS28505
gene id: 349521:HCH_RS28505
uniprot id: Q2S8Q8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

349521:HCH RS31115
gene id: 349521:HCH_RS31115
uniprot id: Q2S760
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS20485
gene id: 349521:HCH_RS20485
uniprot id: Q2SDJ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349521:HCH RS04950
gene id: 349521:HCH_RS04950
uniprot id: Q2SMZ8
names: Subunit
messages: Homotetramer.

349521:HCH RS16235
gene id: 349521:HCH_RS16235
uniprot id: Q2SG65
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS20635
gene id: 349521:HCH_RS20635
uniprot id: Q2SDH0
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

349521:HCH RS23560
gene id: 349521:HCH_RS23560
uniprot id: Q2SBQ3
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

349521:HCH RS19680
gene id: 349521:HCH_RS19680
uniprot id: Q2SE13
names: Subcellular Location Annotation
messages: Cell inner membrane

349521:HCH RS06045
gene id: 349521:HCH_RS06045
uniprot id: Q2SMB7
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

349521:HCH RS19510
gene id: 349521:HCH_RS19510
uniprot id: Q2SE52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

349521:HCH RS07745
gene id: 349521:HCH_RS07745
uniprot id: Q2SLB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

349521:HCH RS22680
gene id: 349521:HCH_RS22680
uniprot id: Q2SC94
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS10990
gene id: 349521:HCH_RS10990
uniprot id: Q2SJE3
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS07805
gene id: 349521:HCH_RS07805
uniprot id: Q2SLA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

349521:HCH RS23340
gene id: 349521:HCH_RS23340
uniprot id: Q2SBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

349521:HCH RS29605
gene id: 349521:HCH_RS29605
uniprot id: Q2S823
names: Similarity
messages: Belongs to the isochorismate synthase family.

349521:HCH RS26500
gene id: 349521:HCH_RS26500
uniprot id: Q2S9X2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

349521:HCH RS18165
gene id: 349521:HCH_RS18165
uniprot id: Q2SEZ2
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

349521:HCH RS24075
gene id: 349521:HCH_RS24075
uniprot id: Q2SBE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS21805
gene id: 349521:HCH_RS21805
uniprot id: Q2SCS5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

349521:HCH RS27925
gene id: 349521:HCH_RS27925
uniprot id: Q2S919
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

349521:HCH RS08105
gene id: 349521:HCH_RS08105
uniprot id: Q2SL42
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

349521:HCH RS27565
gene id: 349521:HCH_RS27565
uniprot id: Q2S998
names: Similarity
messages: Belongs to the TrpC family.

349521:HCH RS04690
gene id: 349521:HCH_RS04690
uniprot id: Q2SN53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS26190
gene id: 349521:HCH_RS26190
uniprot id: Q2SA34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

349521:HCH RS21650
gene id: 349521:HCH_RS21650
uniprot id: Q2SCV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

349521:HCH RS04185
gene id: 349521:HCH_RS04185
uniprot id: Q2SNG1
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

349521:HCH RS26415
gene id: 349521:HCH_RS26415
uniprot id: Q2S9Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

349521:HCH RS17270
gene id: 349521:HCH_RS17270
uniprot id: Q2SFI9
names: Similarity
messages: Belongs to the GcvT family.

349521:HCH RS15560
gene id: 349521:HCH_RS15560
uniprot id: Q2SGL5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS28575
gene id: 349521:HCH_RS28575
uniprot id: Q2S8P2
names: Similarity
messages: Belongs to the YicC/YloC family.

349521:HCH RS23585
gene id: 349521:HCH_RS23585
uniprot id: Q2SBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

349521:HCH RS07740
gene id: 349521:HCH_RS07740
uniprot id: Q2SLB5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

349521:HCH RS20880
gene id: 349521:HCH_RS20880
uniprot id: Q2SDC2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349521:HCH RS04945
gene id: 349521:HCH_RS04945
uniprot id: Q2SMZ9
names: Similarity
messages: Belongs to the allantoicase family.

349521:HCH RS15650
gene id: 349521:HCH_RS15650
uniprot id: Q2SGJ5
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS29190
gene id: 349521:HCH_RS29190
uniprot id: Q2S8B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

349521:HCH RS09715
gene id: 349521:HCH_RS09715
uniprot id: Q2SK57
names: Similarity
messages: Belongs to the peptidase S49 family.

349521:HCH RS31175
gene id: 349521:HCH_RS31175
uniprot id: Q2S747
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS10415
gene id: 349521:HCH_RS10415
uniprot id: Q2SJR7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

349521:HCH RS24205
gene id: 349521:HCH_RS24205
uniprot id: Q2SBB5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349521:HCH RS17595
gene id: 349521:HCH_RS17595
uniprot id: Q2SFC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS17295
gene id: 349521:HCH_RS17295
uniprot id: Q2SFI4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS01960
gene id: 349521:HCH_RS01960
uniprot id: Q2SPT3
names: Similarity
messages: Belongs to the pyruvate kinase family.

349521:HCH RS29195
gene id: 349521:HCH_RS29195
uniprot id: Q2S8B3
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.

349521:HCH RS28920
gene id: 349521:HCH_RS28920
uniprot id: Q2S8H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

349521:HCH RS26050
gene id: 349521:HCH_RS26050
uniprot id: Q2SA64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

349521:HCH RS31285
gene id: 349521:HCH_RS31285
uniprot id: Q2S724
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

349521:HCH RS32055
gene id: 349521:HCH_RS32055
uniprot id: Q2SPK5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS11530
gene id: 349521:HCH_RS11530
uniprot id: Q2SJ26
names: Similarity
messages: Belongs to the DsrF/TusC family.

349521:HCH RS29715
gene id: 349521:HCH_RS29715
uniprot id: Q2S7Z9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS10030
gene id: 349521:HCH_RS10030
uniprot id: Q2SJZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

349521:HCH RS09630
gene id: 349521:HCH_RS09630
uniprot id: Q2SK75
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

349521:HCH RS14655
gene id: 349521:HCH_RS14655
uniprot id: Q2SH54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

349521:HCH RS26345
gene id: 349521:HCH_RS26345
uniprot id: Q2SA03
names: Similarity
messages: Belongs to the Nudix hydrolase family.

349521:HCH RS27530
gene id: 349521:HCH_RS27530
uniprot id: Q2S9A5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS29030
gene id: 349521:HCH_RS29030
uniprot id: Q2S8E8
names: Similarity
messages: Belongs to the oxoprolinase family.

349521:HCH RS21980
gene id: 349521:HCH_RS21980
uniprot id: Q2SCN2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

349521:HCH RS19675
gene id: 349521:HCH_RS19675
uniprot id: Q2SE14
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS02075
gene id: 349521:HCH_RS02075
uniprot id: Q2SPQ9
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

349521:HCH RS02105
gene id: 349521:HCH_RS02105
uniprot id: Q2SPQ3
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

349521:HCH RS19455
gene id: 349521:HCH_RS19455
uniprot id: Q2SE63
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

349521:HCH RS28220
gene id: 349521:HCH_RS28220
uniprot id: Q2S8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349521:HCH RS13010
gene id: 349521:HCH_RS13010
uniprot id: Q2SI63
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

349521:HCH RS16820
gene id: 349521:HCH_RS16820
uniprot id: Q2SFT3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS06945
gene id: 349521:HCH_RS06945
uniprot id: Q2SLS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS09915
gene id: 349521:HCH_RS09915
uniprot id: Q2SK18
names: Similarity
messages: Belongs to the TPP enzyme family.

349521:HCH RS00155
gene id: 349521:HCH_RS00155
uniprot id: Q2SQW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

349521:HCH RS12180
gene id: 349521:HCH_RS12180
uniprot id: Q2SIP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
messages: Cytoplasm

349521:HCH RS21395
gene id: 349521:HCH_RS21395
uniprot id: Q2SD11
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

349521:HCH RS07400
gene id: 349521:HCH_RS07400
uniprot id: Q2SLI5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS12260
gene id: 349521:HCH_RS12260
uniprot id: Q2SIM6
names: Similarity
messages: Belongs to the PrpD family.

349521:HCH RS23840
gene id: 349521:HCH_RS23840
uniprot id: Q2SBJ2
names: Similarity
messages: Belongs to the BolA/IbaG family.

349521:HCH RS04935
gene id: 349521:HCH_RS04935
uniprot id: Q2SN01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

349521:HCH RS23875
gene id: 349521:HCH_RS23875
uniprot id: Q2SBI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

349521:HCH RS06810
gene id: 349521:HCH_RS06810
uniprot id: Q2SLV8
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

349521:HCH RS21615
gene id: 349521:HCH_RS21615
uniprot id: Q2SCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

349521:HCH RS22915
gene id: 349521:HCH_RS22915
uniprot id: Q2SC42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS05355
gene id: 349521:HCH_RS05355
uniprot id: Q2SMQ6
names: Similarity
messages: Belongs to the pirin family.

349521:HCH RS01590
gene id: 349521:HCH_RS01590
uniprot id: Q2SQ13
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

349521:HCH RS03455
gene id: 349521:HCH_RS03455
uniprot id: Q2SNW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

349521:HCH RS03515
gene id: 349521:HCH_RS03515
uniprot id: Q2SNV1
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

349521:HCH RS32570
gene id: 349521:HCH_RS32570
uniprot id: Q2SE93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS05530
gene id: 349521:HCH_RS05530
uniprot id: Q2SMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

349521:HCH RS31070
gene id: 349521:HCH_RS31070
uniprot id: Q2S770
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS08785
gene id: 349521:HCH_RS08785
uniprot id: Q2SKQ3
names: Similarity
messages: Belongs to the peptidase C56 family.

349521:HCH RS11470
gene id: 349521:HCH_RS11470
uniprot id: Q2SJ39
names: Similarity
messages: Belongs to the peptidase S49 family.

349521:HCH RS02220
gene id: 349521:HCH_RS02220
uniprot id: Q2SPN2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS08980
gene id: 349521:HCH_RS08980
uniprot id: Q2SKL0
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

349521:HCH RS24050
gene id: 349521:HCH_RS24050
uniprot id: Q2SBE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

349521:HCH RS22780
gene id: 349521:HCH_RS22780
uniprot id: Q2SC71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349521:HCH RS14055
gene id: 349521:HCH_RS14055
uniprot id: Q2SHI8
names: Similarity
messages: Belongs to the peptidase M24B family.

349521:HCH RS11840
gene id: 349521:HCH_RS11840
uniprot id: Q2SIW9
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

349521:HCH RS24145
gene id: 349521:HCH_RS24145
uniprot id: Q2SBC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

349521:HCH RS13150
gene id: 349521:HCH_RS13150
uniprot id: Q2SI35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS17585
gene id: 349521:HCH_RS17585
uniprot id: Q2SFC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS00490
gene id: 349521:HCH_RS00490
uniprot id: Q2SQP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

349521:HCH RS28915
gene id: 349521:HCH_RS28915
uniprot id: Q2S8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

349521:HCH RS22965
gene id: 349521:HCH_RS22965
uniprot id: Q2SC32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

349521:HCH RS21090
gene id: 349521:HCH_RS21090
uniprot id: Q2SD71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

349521:HCH RS22075
gene id: 349521:HCH_RS22075
uniprot id: Q2SCL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

349521:HCH RS06125
gene id: 349521:HCH_RS06125
uniprot id: Q2SM99
names: Similarity
messages: Belongs to the ABC transporter superfamily.

349521:HCH RS17220
gene id: 349521:HCH_RS17220
uniprot id: Q2SFJ9
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

349521:HCH RS29865
gene id: 349521:HCH_RS29865
uniprot id: Q2S7W9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS09785
gene id: 349521:HCH_RS09785
uniprot id: Q2SK42
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

349521:HCH RS00870
gene id: 349521:HCH_RS00870
uniprot id: Q2SQG7
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS28015
gene id: 349521:HCH_RS28015
uniprot id: Q2S901
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

349521:HCH RS07815
gene id: 349521:HCH_RS07815
uniprot id: Q2SLA1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

349521:HCH RS26950
gene id: 349521:HCH_RS26950
uniprot id: Q2S9N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349521:HCH RS04680
gene id: 349521:HCH_RS04680
uniprot id: Q2SN55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS26805
gene id: 349521:HCH_RS26805
uniprot id: Q2S9R3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

349521:HCH RS17960
gene id: 349521:HCH_RS17960
uniprot id: Q2SF35
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS03665
gene id: 349521:HCH_RS03665
uniprot id: Q2SNS0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

349521:HCH RS11185
gene id: 349521:HCH_RS11185
uniprot id: Q2SJ99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system.
messages: The complex is composed of an ATP-binding protein (RbsA), two transmembrane proteins (RbsC) and a solute-binding protein (RbsB).

349521:HCH RS27815
gene id: 349521:HCH_RS27815
uniprot id: Q2S942
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

349521:HCH RS19885
gene id: 349521:HCH_RS19885
uniprot id: Q2SDW9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

349521:HCH RS08490
gene id: 349521:HCH_RS08490
uniprot id: Q2SKW6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

349521:HCH RS26090
gene id: 349521:HCH_RS26090
uniprot id: Q2SA55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

349521:HCH RS21955
gene id: 349521:HCH_RS21955
uniprot id: Q2SCN6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

349521:HCH RS02440
gene id: 349521:HCH_RS02440
uniprot id: Q2SPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

349521:HCH RS03865
gene id: 349521:HCH_RS03865
uniprot id: Q2SNN0
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

349521:HCH RS00195
gene id: 349521:HCH_RS00195
uniprot id: Q2SQV9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

349521:HCH RS15825
gene id: 349521:HCH_RS15825
uniprot id: Q2SGF6
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS06500
gene id: 349521:HCH_RS06500
uniprot id: Q2SM18
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

349521:HCH RS21595
gene id: 349521:HCH_RS21595
uniprot id: Q2SCW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

349521:HCH RS23370
gene id: 349521:HCH_RS23370
uniprot id: Q2SBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

349521:HCH RS06850
gene id: 349521:HCH_RS06850
uniprot id: Q2SLU9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

349521:HCH RS03175
gene id: 349521:HCH_RS03175
uniprot id: Q2SP23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS04870
gene id: 349521:HCH_RS04870
uniprot id: Q2SN14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.

349521:HCH RS03570
gene id: 349521:HCH_RS03570
uniprot id: Q2SNU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

349521:HCH RS20670
gene id: 349521:HCH_RS20670
uniprot id: Q2SDG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS04800
gene id: 349521:HCH_RS04800
uniprot id: Q2SN30
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

349521:HCH RS32670
gene id: 349521:HCH_RS32670
uniprot id: Q2SCB3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

349521:HCH RS19970
gene id: 349521:HCH_RS19970
uniprot id: Q2SDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS22975
gene id: 349521:HCH_RS22975
uniprot id: Q2SC30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

349521:HCH RS11520
gene id: 349521:HCH_RS11520
uniprot id: Q2SJ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

349521:HCH RS20915
gene id: 349521:HCH_RS20915
uniprot id: Q2SDB4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

349521:HCH RS06110
gene id: 349521:HCH_RS06110
uniprot id: Q2SMA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

349521:HCH RS09110
gene id: 349521:HCH_RS09110
uniprot id: Q2SKI0
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

349521:HCH RS28630
gene id: 349521:HCH_RS28630
uniprot id: Q2S8N0
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

349521:HCH RS10700
gene id: 349521:HCH_RS10700
uniprot id: Q2SJK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

349521:HCH RS19685
gene id: 349521:HCH_RS19685
uniprot id: Q2SE12
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

349521:HCH RS11130
gene id: 349521:HCH_RS11130
uniprot id: Q2SJB3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

349521:HCH RS29750
gene id: 349521:HCH_RS29750
uniprot id: Q2S7Z2
names: Similarity
messages: Belongs to the PspA/IM30 family.

349521:HCH RS15190
gene id: 349521:HCH_RS15190
uniprot id: Q2SGT9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS27430
gene id: 349521:HCH_RS27430
uniprot id: Q2S9C5
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

349521:HCH RS28005
gene id: 349521:HCH_RS28005
uniprot id: Q2S903
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

349521:HCH RS22800
gene id: 349521:HCH_RS22800
uniprot id: Q2SC67
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

349521:HCH RS31885
gene id: 349521:HCH_RS31885
uniprot id: Q2S6P4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS11855
gene id: 349521:HCH_RS11855
uniprot id: Q2SIW6
names: Similarity
messages: Belongs to the UPF0260 family.

349521:HCH RS26595
gene id: 349521:HCH_RS26595
uniprot id: Q2S9V7
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

349521:HCH RS00120
gene id: 349521:HCH_RS00120
uniprot id: Q2SQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS16655
gene id: 349521:HCH_RS16655
uniprot id: Q2SFX1
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

349521:HCH RS17215
gene id: 349521:HCH_RS17215
uniprot id: Q2SFK0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

349521:HCH RS09740
gene id: 349521:HCH_RS09740
uniprot id: Q2SK51
names: Similarity
messages: Belongs to the fabD family.

349521:HCH RS19465
gene id: 349521:HCH_RS19465
uniprot id: Q2SE61
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

349521:HCH RS06845
gene id: 349521:HCH_RS06845
uniprot id: Q2SLV0
names: Similarity
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

349521:HCH RS12680
gene id: 349521:HCH_RS12680
uniprot id: Q2SID8
names: Similarity
messages: Belongs to the NodU/CmcH family.

349521:HCH RS07870
gene id: 349521:HCH_RS07870
uniprot id: Q2SL90
names: Similarity
messages: Belongs to the PhoH family.

349521:HCH RS17000
gene id: 349521:HCH_RS17000
uniprot id: Q2SFP5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS08285
gene id: 349521:HCH_RS08285
uniprot id: Q2SL06
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS05520
gene id: 349521:HCH_RS05520
uniprot id: Q2SMM3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

349521:HCH RS18215
gene id: 349521:HCH_RS18215
uniprot id: Q2SEY2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

349521:HCH RS02590
gene id: 349521:HCH_RS02590
uniprot id: Q2SPF3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

349521:HCH RS18435
gene id: 349521:HCH_RS18435
uniprot id: Q2SET2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS23985
gene id: 349521:HCH_RS23985
uniprot id: Q2SBG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

349521:HCH RS03750
gene id: 349521:HCH_RS03750
uniprot id: Q2SNQ3
names: Similarity
messages: Belongs to the peptidase M4 family.

349521:HCH RS18820
gene id: 349521:HCH_RS18820
uniprot id: Q2SEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS08755
gene id: 349521:HCH_RS08755
uniprot id: Q2SKR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

349521:HCH RS21285
gene id: 349521:HCH_RS21285
uniprot id: Q2SD32
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

349521:HCH RS07600
gene id: 349521:HCH_RS07600
uniprot id: Q2SLE2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

349521:HCH RS23285
gene id: 349521:HCH_RS23285
uniprot id: Q2SBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

349521:HCH RS27650
gene id: 349521:HCH_RS27650
uniprot id: Q2S979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

349521:HCH RS24450
gene id: 349521:HCH_RS24450
uniprot id: Q2SB64
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS01545
gene id: 349521:HCH_RS01545
uniprot id: Q2SQ23
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS26705
gene id: 349521:HCH_RS26705
uniprot id: Q2S9T5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

349521:HCH RS15785
gene id: 349521:HCH_RS15785
uniprot id: Q2SGG5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS04365
gene id: 349521:HCH_RS04365
uniprot id: Q2SNC4
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

349521:HCH RS23375
gene id: 349521:HCH_RS23375
uniprot id: Q2SBU0
names: Similarity
messages: Belongs to the aspartokinase family.

349521:HCH RS17880
gene id: 349521:HCH_RS17880
uniprot id: Q2SF51
names: Similarity
messages: Belongs to the MQO family.

349521:HCH RS15515
gene id: 349521:HCH_RS15515
uniprot id: Q2SGM5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS19995
gene id: 349521:HCH_RS19995
uniprot id: Q2SDU8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

349521:HCH RS10785
gene id: 349521:HCH_RS10785
uniprot id: Q2SJI5
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS19945
gene id: 349521:HCH_RS19945
uniprot id: Q2SDV7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

349521:HCH RS23220
gene id: 349521:HCH_RS23220
uniprot id: Q2SBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

349521:HCH RS28845
gene id: 349521:HCH_RS28845
uniprot id: Q2S8I5
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

349521:HCH RS26175
gene id: 349521:HCH_RS26175
uniprot id: Q2SA37
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

349521:HCH RS23595
gene id: 349521:HCH_RS23595
uniprot id: Q2SBP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

349521:HCH RS22055
gene id: 349521:HCH_RS22055
uniprot id: Q2SCL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

349521:HCH RS23175
gene id: 349521:HCH_RS23175
uniprot id: Q2SBY1
names: Similarity
messages: Belongs to the MotB family.

349521:HCH RS18580
gene id: 349521:HCH_RS18580
uniprot id: Q2SEP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

349521:HCH RS17640
gene id: 349521:HCH_RS17640
uniprot id: Q2SFA9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS30190
gene id: 349521:HCH_RS30190
uniprot id: Q2S7Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349521:HCH RS12265
gene id: 349521:HCH_RS12265
uniprot id: Q2SIM5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

349521:HCH RS01025
gene id: 349521:HCH_RS01025
uniprot id: Q2SQD3
names: Similarity
messages: Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family.

349521:HCH RS02445
gene id: 349521:HCH_RS02445
uniprot id: Q2SPI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).

349521:HCH RS32235
gene id: 349521:HCH_RS32235
uniprot id: Q2SK17
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS00865
gene id: 349521:HCH_RS00865
uniprot id: Q2SQG8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

349521:HCH RS27960
gene id: 349521:HCH_RS27960
uniprot id: Q2S912
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

349521:HCH RS30035
gene id: 349521:HCH_RS30035
uniprot id: Q2S7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS00045
gene id: 349521:HCH_RS00045
uniprot id: Q2SQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS05820
gene id: 349521:HCH_RS05820
uniprot id: Q2SMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS00510
gene id: 349521:HCH_RS00510
uniprot id: Q2SQP4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

349521:HCH RS31655
gene id: 349521:HCH_RS31655
uniprot id: Q2S6U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
messages: Binds 2 manganese ions per subunit.
messages: Splits dipeptides with a prolyl residue in the C-terminal position.

349521:HCH RS05095
gene id: 349521:HCH_RS05095
uniprot id: Q2SMW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS30785
gene id: 349521:HCH_RS30785
uniprot id: Q2S7D4
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

349521:HCH RS14740
gene id: 349521:HCH_RS14740
uniprot id: Q2SH38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctE/SipB/YopB family.
messages: Host membrane

349521:HCH RS19610
gene id: 349521:HCH_RS19610
uniprot id: Q2SE30
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS12250
gene id: 349521:HCH_RS12250
uniprot id: Q2SIM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

349521:HCH RS01470
gene id: 349521:HCH_RS01470
uniprot id: Q2SQ39
names: Similarity
messages: Belongs to the YkuD family.

349521:HCH RS32635
gene id: 349521:HCH_RS32635
uniprot id: Q2SD46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

349521:HCH RS18705
gene id: 349521:HCH_RS18705
uniprot id: Q2SEM4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

349521:HCH RS02515
gene id: 349521:HCH_RS02515
uniprot id: Q2SPG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

349521:HCH RS00720
gene id: 349521:HCH_RS00720
uniprot id: Q2SQJ7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

349521:HCH RS07650
gene id: 349521:HCH_RS07650
uniprot id: Q2SLD1
names: Similarity
messages: Belongs to the peptidase S8 family.

349521:HCH RS30950
gene id: 349521:HCH_RS30950
uniprot id: Q2S798
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

349521:HCH RS08135
gene id: 349521:HCH_RS08135
uniprot id: Q2SL36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.
messages: Periplasm

349521:HCH RS19965
gene id: 349521:HCH_RS19965
uniprot id: Q2SDV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

349521:HCH RS24240
gene id: 349521:HCH_RS24240
uniprot id: Q2SBA8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

349521:HCH RS19930
gene id: 349521:HCH_RS19930
uniprot id: Q2SDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

349521:HCH RS22365
gene id: 349521:HCH_RS22365
uniprot id: Q2SCF6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

349521:HCH RS04565
gene id: 349521:HCH_RS04565
uniprot id: Q2SN79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

349521:HCH RS04370
gene id: 349521:HCH_RS04370
uniprot id: Q2SNC3
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

349521:HCH RS27560
gene id: 349521:HCH_RS27560
uniprot id: Q2S999
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

349521:HCH RS16600
gene id: 349521:HCH_RS16600
uniprot id: Q2SFY4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

349521:HCH RS27385
gene id: 349521:HCH_RS27385
uniprot id: Q2S9D8
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

349521:HCH RS18050
gene id: 349521:HCH_RS18050
uniprot id: Q2SF17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

349521:HCH RS15655
gene id: 349521:HCH_RS15655
uniprot id: Q2SGJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS00655
gene id: 349521:HCH_RS00655
uniprot id: Q2SQL2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

349521:HCH RS27945
gene id: 349521:HCH_RS27945
uniprot id: Q2S915
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

349521:HCH RS22165
gene id: 349521:HCH_RS22165
uniprot id: Q2SCJ6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

349521:HCH RS10085
gene id: 349521:HCH_RS10085
uniprot id: Q2SJY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiV subfamily.
messages: Forms an heterodimer with UbiU.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

349521:HCH RS31535
gene id: 349521:HCH_RS31535
uniprot id: Q2S6X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

349521:HCH RS17665
gene id: 349521:HCH_RS17665
uniprot id: Q2SFA4
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

349521:HCH RS08165
gene id: 349521:HCH_RS08165
uniprot id: Q2SL30
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

349521:HCH RS01855
gene id: 349521:HCH_RS01855
uniprot id: Q2SPV4
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

349521:HCH RS10160
gene id: 349521:HCH_RS10160
uniprot id: Q2SJW9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS08300
gene id: 349521:HCH_RS08300
uniprot id: Q2SL03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS28240
gene id: 349521:HCH_RS28240
uniprot id: Q2S8W3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

349521:HCH RS11125
gene id: 349521:HCH_RS11125
uniprot id: Q2SJB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

349521:HCH RS05890
gene id: 349521:HCH_RS05890
uniprot id: Q2SME7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS03490
gene id: 349521:HCH_RS03490
uniprot id: Q2SNV6
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

349521:HCH RS09555
gene id: 349521:HCH_RS09555
uniprot id: Q2SK90
names: Function
names: Similarity
messages: Belongs to the peptidase C56 family.
messages: Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate.

349521:HCH RS21310
gene id: 349521:HCH_RS21310
uniprot id: Q2SD27
names: Similarity
messages: Belongs to the citrate synthase family.

349521:HCH RS05680
gene id: 349521:HCH_RS05680
uniprot id: Q2SMJ1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS08080
gene id: 349521:HCH_RS08080
uniprot id: Q2SL47
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS22335
gene id: 349521:HCH_RS22335
uniprot id: Q2SCG2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS20225
gene id: 349521:HCH_RS20225
uniprot id: Q2SDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

349521:HCH RS23255
gene id: 349521:HCH_RS23255
uniprot id: Q2SBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

349521:HCH RS13380
gene id: 349521:HCH_RS13380
uniprot id: Q2SHY5
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS28585
gene id: 349521:HCH_RS28585
uniprot id: Q2S8P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

349521:HCH RS29990
gene id: 349521:HCH_RS29990
uniprot id: Q2S7U3
names: Similarity
messages: Belongs to the asparaginase 1 family.

349521:HCH RS31900
gene id: 349521:HCH_RS31900
uniprot id: Q2S6P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

349521:HCH RS09705
gene id: 349521:HCH_RS09705
uniprot id: Q2SK59
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

349521:HCH RS27880
gene id: 349521:HCH_RS27880
uniprot id: Q2S928
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

349521:HCH RS12135
gene id: 349521:HCH_RS12135
uniprot id: Q2SIQ2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349521:HCH RS02335
gene id: 349521:HCH_RS02335
uniprot id: Q2SPK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS14045
gene id: 349521:HCH_RS14045
uniprot id: Q2SHJ0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS23250
gene id: 349521:HCH_RS23250
uniprot id: Q2SBW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

349521:HCH RS32425
gene id: 349521:HCH_RS32425
uniprot id: Q2SGG3
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

349521:HCH RS27845
gene id: 349521:HCH_RS27845
uniprot id: Q2S936
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

349521:HCH RS13570
gene id: 349521:HCH_RS13570
uniprot id: Q2SHU1
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit.

349521:HCH RS11845
gene id: 349521:HCH_RS11845
uniprot id: Q2SIW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

349521:HCH RS19500
gene id: 349521:HCH_RS19500
uniprot id: Q2SE54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS06720
gene id: 349521:HCH_RS06720
uniprot id: Q2SLX6
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

349521:HCH RS15690
gene id: 349521:HCH_RS15690
uniprot id: Q2SGI7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS08590
gene id: 349521:HCH_RS08590
uniprot id: Q2SKU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

349521:HCH RS03295
gene id: 349521:HCH_RS03295
uniprot id: Q2SNZ5
names: Similarity
messages: Belongs to the glutamine synthetase family.

349521:HCH RS03475
gene id: 349521:HCH_RS03475
uniprot id: Q2SNV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

349521:HCH RS28480
gene id: 349521:HCH_RS28480
uniprot id: Q2S8R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

349521:HCH RS06925
gene id: 349521:HCH_RS06925
uniprot id: Q2SLT3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

349521:HCH RS18075
gene id: 349521:HCH_RS18075
uniprot id: Q2SF12
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

349521:HCH RS23720
gene id: 349521:HCH_RS23720
uniprot id: Q2SBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

349521:HCH RS12495
gene id: 349521:HCH_RS12495
uniprot id: Q2SIH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

349521:HCH RS23880
gene id: 349521:HCH_RS23880
uniprot id: Q2SBI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.

349521:HCH RS24115
gene id: 349521:HCH_RS24115
uniprot id: Q2SBD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

349521:HCH RS03120
gene id: 349521:HCH_RS03120
uniprot id: Q2SP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS10070
gene id: 349521:HCH_RS10070
uniprot id: Q2SJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS21995
gene id: 349521:HCH_RS21995
uniprot id: Q2SCM9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

349521:HCH RS02565
gene id: 349521:HCH_RS02565
uniprot id: Q2SPF8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

349521:HCH RS11005
gene id: 349521:HCH_RS11005
uniprot id: Q2SJE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS08085
gene id: 349521:HCH_RS08085
uniprot id: Q2SL46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

349521:HCH RS31710
gene id: 349521:HCH_RS31710
uniprot id: Q2S6T0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

349521:HCH RS03485
gene id: 349521:HCH_RS03485
uniprot id: Q2SNV7
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

349521:HCH RS22540
gene id: 349521:HCH_RS22540
uniprot id: Q2SCC2
names: Similarity
messages: Belongs to the GSP E family.

349521:HCH RS06095
gene id: 349521:HCH_RS06095
uniprot id: Q2SMA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

349521:HCH RS08445
gene id: 349521:HCH_RS08445
uniprot id: Q2SKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

349521:HCH RS23300
gene id: 349521:HCH_RS23300
uniprot id: Q2SBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

349521:HCH RS29945
gene id: 349521:HCH_RS29945
uniprot id: Q2S7V2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS05720
gene id: 349521:HCH_RS05720
uniprot id: Q2SMI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

349521:HCH RS24570
gene id: 349521:HCH_RS24570
uniprot id: Q2SB38
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS01975
gene id: 349521:HCH_RS01975
uniprot id: Q2SPT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

349521:HCH RS24040
gene id: 349521:HCH_RS24040
uniprot id: Q2SBF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS10140
gene id: 349521:HCH_RS10140
uniprot id: Q2SJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

349521:HCH RS08885
gene id: 349521:HCH_RS08885
uniprot id: Q2SKN2
names: Subunit
messages: Homodimer.

349521:HCH RS04540
gene id: 349521:HCH_RS04540
uniprot id: Q2SN85
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

349521:HCH RS11990
gene id: 349521:HCH_RS11990
uniprot id: Q2SIT5
names: Similarity
messages: Belongs to the MlaA family.

349521:HCH RS27045
gene id: 349521:HCH_RS27045
uniprot id: Q2S9L3
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

349521:HCH RS02670
gene id: 349521:HCH_RS02670
uniprot id: Q2SPD6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

349521:HCH RS02450
gene id: 349521:HCH_RS02450
uniprot id: Q2SPI2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS28375
gene id: 349521:HCH_RS28375
uniprot id: Q2S8T4
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS06935
gene id: 349521:HCH_RS06935
uniprot id: Q2SLT1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

349521:HCH RS12145
gene id: 349521:HCH_RS12145
uniprot id: Q2SIQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

349521:HCH RS18985
gene id: 349521:HCH_RS18985
uniprot id: Q2SEG1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS24220
gene id: 349521:HCH_RS24220
uniprot id: Q2SBB2
names: Similarity
messages: Belongs to the MotB family.

349521:HCH RS16780
gene id: 349521:HCH_RS16780
uniprot id: Q2SFU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349521:HCH RS10075
gene id: 349521:HCH_RS10075
uniprot id: Q2SJY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

349521:HCH RS34550
gene id: 349521:HCH_RS34550
uniprot id: Q2SN15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS01340
gene id: 349521:HCH_RS01340
uniprot id: Q2SQ67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

349521:HCH RS07685
gene id: 349521:HCH_RS07685
uniprot id: Q2SLC6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS32340
gene id: 349521:HCH_RS32340
uniprot id: Q2SHZ0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS04380
gene id: 349521:HCH_RS04380
uniprot id: Q2SNC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

349521:HCH RS20060
gene id: 349521:HCH_RS20060
uniprot id: Q2SDT3
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS31045
gene id: 349521:HCH_RS31045
uniprot id: Q2S777
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

349521:HCH RS13710
gene id: 349521:HCH_RS13710
uniprot id: Q2SHR3
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

349521:HCH RS23945
gene id: 349521:HCH_RS23945
uniprot id: Q2SBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

349521:HCH RS02625
gene id: 349521:HCH_RS02625
uniprot id: Q2SPE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

349521:HCH RS08495
gene id: 349521:HCH_RS08495
uniprot id: Q2SKW5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

349521:HCH RS01785
gene id: 349521:HCH_RS01785
uniprot id: Q2SPW6
names: Similarity
messages: Belongs to the phage portal family. PBSX subfamily.

349521:HCH RS11915
gene id: 349521:HCH_RS11915
uniprot id: Q2SIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

349521:HCH RS23710
gene id: 349521:HCH_RS23710
uniprot id: Q2SBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS25135
gene id: 349521:HCH_RS25135
uniprot id: Q2SAR4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS20065
gene id: 349521:HCH_RS20065
uniprot id: Q2SDT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS11540
gene id: 349521:HCH_RS11540
uniprot id: Q2SJ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

349521:HCH RS27420
gene id: 349521:HCH_RS27420
uniprot id: Q2S9C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

349521:HCH RS11055
gene id: 349521:HCH_RS11055
uniprot id: Q2SJC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

349521:HCH RS28485
gene id: 349521:HCH_RS28485
uniprot id: Q2S8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

349521:HCH RS06345
gene id: 349521:HCH_RS06345
uniprot id: Q2SM51
names: Similarity
messages: Belongs to the HesB/IscA family.

349521:HCH RS09750
gene id: 349521:HCH_RS09750
uniprot id: Q2SK49
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

349521:HCH RS22770
gene id: 349521:HCH_RS22770
uniprot id: Q2SC73
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

349521:HCH RS08025
gene id: 349521:HCH_RS08025
uniprot id: Q2SL58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

349521:HCH RS00175
gene id: 349521:HCH_RS00175
uniprot id: Q2SQW3
names: Similarity
messages: Belongs to the MotB family.

349521:HCH RS32770
gene id: 349521:HCH_RS32770
uniprot id: Q2S9U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS24825
gene id: 349521:HCH_RS24825
uniprot id: Q2SAY4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

349521:HCH RS32890
gene id: 349521:HCH_RS32890
uniprot id: Q2S6Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

349521:HCH RS26675
gene id: 349521:HCH_RS26675
uniprot id: Q2S9U2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

349521:HCH RS22180
gene id: 349521:HCH_RS22180
uniprot id: Q2SCJ3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

349521:HCH RS02540
gene id: 349521:HCH_RS02540
uniprot id: Q2SPG4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

349521:HCH RS21205
gene id: 349521:HCH_RS21205
uniprot id: Q2SD47
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

349521:HCH RS28135
gene id: 349521:HCH_RS28135
uniprot id: Q2S8Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

349521:HCH RS29450
gene id: 349521:HCH_RS29450
uniprot id: Q2S856
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS21270
gene id: 349521:HCH_RS21270
uniprot id: Q2SD35
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

349521:HCH RS09975
gene id: 349521:HCH_RS09975
uniprot id: Q2SK05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

349521:HCH RS26045
gene id: 349521:HCH_RS26045
uniprot id: Q2SA65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

349521:HCH RS00600
gene id: 349521:HCH_RS00600
uniprot id: Q2SQM5
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase.

349521:HCH RS14925
gene id: 349521:HCH_RS14925
uniprot id: Q2SGZ7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS28890
gene id: 349521:HCH_RS28890
uniprot id: Q2S8I0
names: Similarity
messages: Belongs to the P(II) protein family.

349521:HCH RS01510
gene id: 349521:HCH_RS01510
uniprot id: Q2SQ31
names: Similarity
messages: Belongs to the glutamate synthase family.

349521:HCH RS02640
gene id: 349521:HCH_RS02640
uniprot id: Q2SPE3
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

349521:HCH RS03635
gene id: 349521:HCH_RS03635
uniprot id: Q2SNS6
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS05540
gene id: 349521:HCH_RS05540
uniprot id: Q2SML9
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

349521:HCH RS19550
gene id: 349521:HCH_RS19550
uniprot id: Q2SE43
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

349521:HCH RS00935
gene id: 349521:HCH_RS00935
uniprot id: Q2SQF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS31930
gene id: 349521:HCH_RS31930
uniprot id: Q2S6N5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

349521:HCH RS11725
gene id: 349521:HCH_RS11725
uniprot id: Q2SIZ2
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

349521:HCH RS06325
gene id: 349521:HCH_RS06325
uniprot id: Q2SM55
names: Similarity
messages: Belongs to the DinB family.

349521:HCH RS23235
gene id: 349521:HCH_RS23235
uniprot id: Q2SBW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

349521:HCH RS31910
gene id: 349521:HCH_RS31910
uniprot id: Q2S6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

349521:HCH RS06950
gene id: 349521:HCH_RS06950
uniprot id: Q2SLS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

349521:HCH RS00150
gene id: 349521:HCH_RS00150
uniprot id: Q2SQW9
names: Similarity
messages: Belongs to the DprA/Smf family.

349521:HCH RS11075
gene id: 349521:HCH_RS11075
uniprot id: Q2SJC5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS20215
gene id: 349521:HCH_RS20215
uniprot id: Q2SDQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

349521:HCH RS08255
gene id: 349521:HCH_RS08255
uniprot id: Q2SL12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS31275
gene id: 349521:HCH_RS31275
uniprot id: Q2S726
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

349521:HCH RS23810
gene id: 349521:HCH_RS23810
uniprot id: Q2SBJ9
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

349521:HCH RS32705
gene id: 349521:HCH_RS32705
uniprot id: Q2SB99
names: Similarity
messages: Belongs to the transglycosylase Slt family.

349521:HCH RS07115
gene id: 349521:HCH_RS07115
uniprot id: Q2SLP3
names: Similarity
messages: Belongs to the peptidase M28 family. M28A subfamily.

349521:HCH RS22185
gene id: 349521:HCH_RS22185
uniprot id: Q2SCJ2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

349521:HCH RS02510
gene id: 349521:HCH_RS02510
uniprot id: Q2SPH0
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

349521:HCH RS26925
gene id: 349521:HCH_RS26925
uniprot id: Q2S9N9
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

349521:HCH RS17515
gene id: 349521:HCH_RS17515
uniprot id: Q2SFD8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

349521:HCH RS12025
gene id: 349521:HCH_RS12025
uniprot id: Q2SIS8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS07800
gene id: 349521:HCH_RS07800
uniprot id: Q2SLA4
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

349521:HCH RS09755
gene id: 349521:HCH_RS09755
uniprot id: Q2SK48
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

349521:HCH RS23475
gene id: 349521:HCH_RS23475
uniprot id: Q2SBS0
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

349521:HCH RS23185
gene id: 349521:HCH_RS23185
uniprot id: Q2SBX9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

349521:HCH RS11995
gene id: 349521:HCH_RS11995
uniprot id: Q2SIT4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS26690
gene id: 349521:HCH_RS26690
uniprot id: Q2S9T9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

349521:HCH RS26215
gene id: 349521:HCH_RS26215
uniprot id: Q2SA29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

349521:HCH RS03555
gene id: 349521:HCH_RS03555
uniprot id: Q2SNU3
names: Subcellular Location Annotation
messages: Nucleus

349521:HCH RS15110
gene id: 349521:HCH_RS15110
uniprot id: Q2SGV6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

349521:HCH RS10540
gene id: 349521:HCH_RS10540
uniprot id: Q2SJN8
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

349521:HCH RS26815
gene id: 349521:HCH_RS26815
uniprot id: Q2S9R1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

349521:HCH RS27820
gene id: 349521:HCH_RS27820
uniprot id: Q2S941
names: Function
names: Subunit
messages: Homotetramer.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

349521:HCH RS26715
gene id: 349521:HCH_RS26715
uniprot id: Q2S9T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS29545
gene id: 349521:HCH_RS29545
uniprot id: Q2S836
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS27090
gene id: 349521:HCH_RS27090
uniprot id: Q2S9K4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

349521:HCH RS28985
gene id: 349521:HCH_RS28985
uniprot id: Q2S8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

349521:HCH RS07940
gene id: 349521:HCH_RS07940
uniprot id: Q2SL75
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

349521:HCH RS18590
gene id: 349521:HCH_RS18590
uniprot id: Q2SEP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm

349521:HCH RS09970
gene id: 349521:HCH_RS09970
uniprot id: Q2SK06
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

349521:HCH RS17275
gene id: 349521:HCH_RS17275
uniprot id: Q2SFI8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

349521:HCH RS05625
gene id: 349521:HCH_RS05625
uniprot id: Q2SMK2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS23405
gene id: 349521:HCH_RS23405
uniprot id: Q2SBT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

349521:HCH RS27440
gene id: 349521:HCH_RS27440
uniprot id: Q2S9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

349521:HCH RS15400
gene id: 349521:HCH_RS15400
uniprot id: Q2SGP9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS19360
gene id: 349521:HCH_RS19360
uniprot id: Q2SE86
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS07190
gene id: 349521:HCH_RS07190
uniprot id: Q2SLN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

349521:HCH RS10550
gene id: 349521:HCH_RS10550
uniprot id: Q2SJN6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

349521:HCH RS01450
gene id: 349521:HCH_RS01450
uniprot id: Q2SQ43
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

349521:HCH RS00210
gene id: 349521:HCH_RS00210
uniprot id: Q2SQV6
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS25095
gene id: 349521:HCH_RS25095
uniprot id: Q2SAS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS00075
gene id: 349521:HCH_RS00075
uniprot id: Q2SQY3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS22545
gene id: 349521:HCH_RS22545
uniprot id: Q2SCC1
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

349521:HCH RS08065
gene id: 349521:HCH_RS08065
uniprot id: Q2SL50
names: Similarity
messages: Belongs to the threonine synthase family.

349521:HCH RS23505
gene id: 349521:HCH_RS23505
uniprot id: Q2SBR5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

349521:HCH RS27485
gene id: 349521:HCH_RS27485
uniprot id: Q2S9B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

349521:HCH RS18225
gene id: 349521:HCH_RS18225
uniprot id: Q2SEY0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

349521:HCH RS26720
gene id: 349521:HCH_RS26720
uniprot id: Q2S9T2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

349521:HCH RS22945
gene id: 349521:HCH_RS22945
uniprot id: Q2SC36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cytoplasm

349521:HCH RS30860
gene id: 349521:HCH_RS30860
uniprot id: Q2S7B7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS20610
gene id: 349521:HCH_RS20610
uniprot id: Q2SDH5
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

349521:HCH RS06375
gene id: 349521:HCH_RS06375
uniprot id: Q2SM44
names: Similarity
messages: Belongs to the UPF0438 family.

349521:HCH RS23870
gene id: 349521:HCH_RS23870
uniprot id: Q2SBI6
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

349521:HCH RS25020
gene id: 349521:HCH_RS25020
uniprot id: Q2SAU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

349521:HCH RS07360
gene id: 349521:HCH_RS07360
uniprot id: Q2SLJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS26960
gene id: 349521:HCH_RS26960
uniprot id: Q2S9N2
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

349521:HCH RS31410
gene id: 349521:HCH_RS31410
uniprot id: Q2S6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

349521:HCH RS28710
gene id: 349521:HCH_RS28710
uniprot id: Q2S8L4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

349521:HCH RS28410
gene id: 349521:HCH_RS28410
uniprot id: Q2S8S7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS20130
gene id: 349521:HCH_RS20130
uniprot id: Q2SDR9
names: Subcellular Location Annotation
messages: Cell inner membrane

349521:HCH RS26205
gene id: 349521:HCH_RS26205
uniprot id: Q2SA31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

349521:HCH RS24620
gene id: 349521:HCH_RS24620
uniprot id: Q2SB28
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS10405
gene id: 349521:HCH_RS10405
uniprot id: Q2SJR9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

349521:HCH RS28275
gene id: 349521:HCH_RS28275
uniprot id: Q2S8V6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

349521:HCH RS07310
gene id: 349521:HCH_RS07310
uniprot id: Q2SLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS19980
gene id: 349521:HCH_RS19980
uniprot id: Q2SDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

349521:HCH RS02270
gene id: 349521:HCH_RS02270
uniprot id: Q2SPM2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

349521:HCH RS17600
gene id: 349521:HCH_RS17600
uniprot id: Q2SFB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS01355
gene id: 349521:HCH_RS01355
uniprot id: Q2SQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS17545
gene id: 349521:HCH_RS17545
uniprot id: Q2SFD1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

349521:HCH RS07750
gene id: 349521:HCH_RS07750
uniprot id: Q2SLB3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

349521:HCH RS09680
gene id: 349521:HCH_RS09680
uniprot id: Q2SK65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

349521:HCH RS00930
gene id: 349521:HCH_RS00930
uniprot id: Q2SQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS13770
gene id: 349521:HCH_RS13770
uniprot id: Q2SHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

349521:HCH RS17905
gene id: 349521:HCH_RS17905
uniprot id: Q2SF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Cell membrane
messages: Membrane

349521:HCH RS21680
gene id: 349521:HCH_RS21680
uniprot id: Q2SCU9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS08570
gene id: 349521:HCH_RS08570
uniprot id: Q2SKU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

349521:HCH RS05570
gene id: 349521:HCH_RS05570
uniprot id: Q2SML4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

349521:HCH RS24290
gene id: 349521:HCH_RS24290
uniprot id: Q2SB98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

349521:HCH RS13890
gene id: 349521:HCH_RS13890
uniprot id: Q2SHM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

349521:HCH RS30185
gene id: 349521:HCH_RS30185
uniprot id: Q2S7Q3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

349521:HCH RS22750
gene id: 349521:HCH_RS22750
uniprot id: Q2SC80
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

349521:HCH RS05270
gene id: 349521:HCH_RS05270
uniprot id: Q2SMS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

349521:HCH RS31590
gene id: 349521:HCH_RS31590
uniprot id: Q2S6V8
names: Similarity
messages: Belongs to the thioesterase family.

349521:HCH RS21330
gene id: 349521:HCH_RS21330
uniprot id: Q2SD23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
messages: Cytoplasm
messages: Heterotetramer of two alpha chains (FadB) and two beta chains (FadA).

349521:HCH RS21820
gene id: 349521:HCH_RS21820
uniprot id: Q2SCS1
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

349521:HCH RS00700
gene id: 349521:HCH_RS00700
uniprot id: Q2SQK3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

349521:HCH RS10090
gene id: 349521:HCH_RS10090
uniprot id: Q2SJY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase U32 family. UbiU subfamily.
messages: Forms an heterodimer with UbiV.
messages: Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway.

349521:HCH RS05130
gene id: 349521:HCH_RS05130
uniprot id: Q2SMW0
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

349521:HCH RS05595
gene id: 349521:HCH_RS05595
uniprot id: Q2SMK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

349521:HCH RS19960
gene id: 349521:HCH_RS19960
uniprot id: Q2SDV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

349521:HCH RS19495
gene id: 349521:HCH_RS19495
uniprot id: Q2SE55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

349521:HCH RS24650
gene id: 349521:HCH_RS24650
uniprot id: Q2SB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

349521:HCH RS07290
gene id: 349521:HCH_RS07290
uniprot id: Q2SLL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

349521:HCH RS05670
gene id: 349521:HCH_RS05670
uniprot id: Q2SMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

349521:HCH RS01970
gene id: 349521:HCH_RS01970
uniprot id: Q2SPT1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.

349521:HCH RS28230
gene id: 349521:HCH_RS28230
uniprot id: Q2S8W5
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

349521:HCH RS10210
gene id: 349521:HCH_RS10210
uniprot id: Q2SJV9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS01525
gene id: 349521:HCH_RS01525
uniprot id: Q2SQ27
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS27985
gene id: 349521:HCH_RS27985
uniprot id: Q2S907
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

349521:HCH RS07990
gene id: 349521:HCH_RS07990
uniprot id: Q2SL65
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

349521:HCH RS05495
gene id: 349521:HCH_RS05495
uniprot id: Q2SMM8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

349521:HCH RS08765
gene id: 349521:HCH_RS08765
uniprot id: Q2SKQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

349521:HCH RS08050
gene id: 349521:HCH_RS08050
uniprot id: Q2SL53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

349521:HCH RS14595
gene id: 349521:HCH_RS14595
uniprot id: Q2SH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

349521:HCH RS30870
gene id: 349521:HCH_RS30870
uniprot id: Q2S7B5
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS12645
gene id: 349521:HCH_RS12645
uniprot id: Q2SIE6
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

349521:HCH RS30430
gene id: 349521:HCH_RS30430
uniprot id: Q2S7K4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS27970
gene id: 349521:HCH_RS27970
uniprot id: Q2S8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

349521:HCH RS31240
gene id: 349521:HCH_RS31240
uniprot id: Q2S733
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS11100
gene id: 349521:HCH_RS11100
uniprot id: Q2SJB9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

349521:HCH RS27965
gene id: 349521:HCH_RS27965
uniprot id: Q2S911
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

349521:HCH RS27995
gene id: 349521:HCH_RS27995
uniprot id: Q2S905
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

349521:HCH RS02015
gene id: 349521:HCH_RS02015
uniprot id: Q2SPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS06915
gene id: 349521:HCH_RS06915
uniprot id: Q2SLT5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

349521:HCH RS02500
gene id: 349521:HCH_RS02500
uniprot id: Q2SPH2
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

349521:HCH RS26980
gene id: 349521:HCH_RS26980
uniprot id: Q2S9M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

349521:HCH RS09260
gene id: 349521:HCH_RS09260
uniprot id: Q2SKE8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS11920
gene id: 349521:HCH_RS11920
uniprot id: Q2SIV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

349521:HCH RS03285
gene id: 349521:HCH_RS03285
uniprot id: Q2SNZ7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

349521:HCH RS23885
gene id: 349521:HCH_RS23885
uniprot id: Q2SBI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

349521:HCH RS22875
gene id: 349521:HCH_RS22875
uniprot id: Q2SC51
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS25800
gene id: 349521:HCH_RS25800
uniprot id: Q2SAC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS04035
gene id: 349521:HCH_RS04035
uniprot id: Q2SNJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

349521:HCH RS16580
gene id: 349521:HCH_RS16580
uniprot id: Q2SFY8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS16995
gene id: 349521:HCH_RS16995
uniprot id: Q2SFP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

349521:HCH RS10895
gene id: 349521:HCH_RS10895
uniprot id: Q2SJG2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS07315
gene id: 349521:HCH_RS07315
uniprot id: Q2SLK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

349521:HCH RS31050
gene id: 349521:HCH_RS31050
uniprot id: Q2S776
names: Similarity
messages: Belongs to the IMPACT family.

349521:HCH RS02620
gene id: 349521:HCH_RS02620
uniprot id: Q2SPE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

349521:HCH RS19005
gene id: 349521:HCH_RS19005
uniprot id: Q2SEF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase chaperone family.
messages: Cell inner membrane
messages: May be involved in the folding of the extracellular lipase during its passage through the periplasm.

349521:HCH RS16160
gene id: 349521:HCH_RS16160
uniprot id: Q2SG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

349521:HCH RS08175
gene id: 349521:HCH_RS08175
uniprot id: Q2SL28
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

349521:HCH RS23440
gene id: 349521:HCH_RS23440
uniprot id: Q2SBS7
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

349521:HCH RS16250
gene id: 349521:HCH_RS16250
uniprot id: Q2SG62
names: Similarity
messages: Belongs to the arginase family.

349521:HCH RS24080
gene id: 349521:HCH_RS24080
uniprot id: Q2SBE1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS10205
gene id: 349521:HCH_RS10205
uniprot id: Q2SJW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

349521:HCH RS27940
gene id: 349521:HCH_RS27940
uniprot id: Q2S916
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

349521:HCH RS00970
gene id: 349521:HCH_RS00970
uniprot id: Q2SQE7
names: Similarity
messages: Belongs to the elongation factor P family.

349521:HCH RS04780
gene id: 349521:HCH_RS04780
uniprot id: Q2SN34
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

349521:HCH RS02235
gene id: 349521:HCH_RS02235
uniprot id: Q2SPM9
names: Similarity
messages: Belongs to the UPF0325 family.

349521:HCH RS10960
gene id: 349521:HCH_RS10960
uniprot id: Q2SJE9
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

349521:HCH RS25115
gene id: 349521:HCH_RS25115
uniprot id: Q2SAR8
names: Similarity
messages: Belongs to the YciI family.

349521:HCH RS23540
gene id: 349521:HCH_RS23540
uniprot id: Q2SBQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

349521:HCH RS11405
gene id: 349521:HCH_RS11405
uniprot id: Q2SJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS11040
gene id: 349521:HCH_RS11040
uniprot id: Q2SJD2
names: Similarity
messages: Belongs to the TrpF family.

349521:HCH RS26405
gene id: 349521:HCH_RS26405
uniprot id: Q2S9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that is essential for cell division.

349521:HCH RS04900
gene id: 349521:HCH_RS04900
uniprot id: Q2SN08
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

349521:HCH RS14245
gene id: 349521:HCH_RS14245
uniprot id: Q2SHE4
names: Similarity
messages: Belongs to the proline racemase family.

349521:HCH RS22330
gene id: 349521:HCH_RS22330
uniprot id: Q2SCG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

349521:HCH RS25275
gene id: 349521:HCH_RS25275
uniprot id: Q2SAN0
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

349521:HCH RS01990
gene id: 349521:HCH_RS01990
uniprot id: Q2SPS7
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

349521:HCH RS21300
gene id: 349521:HCH_RS21300
uniprot id: Q2SD29
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

349521:HCH RS14400
gene id: 349521:HCH_RS14400
uniprot id: Q2SHA9
names: Similarity
messages: Belongs to the AHA1 family.

349521:HCH RS22300
gene id: 349521:HCH_RS22300
uniprot id: Q2SCG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

349521:HCH RS28510
gene id: 349521:HCH_RS28510
uniprot id: Q2S8Q7
names: Similarity
messages: Belongs to the glutamine synthetase family.

349521:HCH RS07760
gene id: 349521:HCH_RS07760
uniprot id: Q2SLB1
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

349521:HCH RS24505
gene id: 349521:HCH_RS24505
uniprot id: Q2SB52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS03640
gene id: 349521:HCH_RS03640
uniprot id: Q2SNS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS30890
gene id: 349521:HCH_RS30890
uniprot id: Q2S7B1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

349521:HCH RS06145
gene id: 349521:HCH_RS06145
uniprot id: Q2SM94
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

349521:HCH RS25025
gene id: 349521:HCH_RS25025
uniprot id: Q2SAU0
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

349521:HCH RS26240
gene id: 349521:HCH_RS26240
uniprot id: Q2SA24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

349521:HCH RS29565
gene id: 349521:HCH_RS29565
uniprot id: Q2S832
names: Similarity
messages: Belongs to the thioredoxin family.

349521:HCH RS30230
gene id: 349521:HCH_RS30230
uniprot id: Q2S7P4
names: Function
names: Similarity
messages: A cysteine desulfhydrase that generates hydrogen sulfide, H(2)S. The H(2)S produced by this enzyme may modulate central metabolism.
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family. Cds1 subfamily.

349521:HCH RS02110
gene id: 349521:HCH_RS02110
uniprot id: Q2SPQ2
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

349521:HCH RS07700
gene id: 349521:HCH_RS07700
uniprot id: Q2SLC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS10355
gene id: 349521:HCH_RS10355
uniprot id: Q2SJS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

349521:HCH RS15470
gene id: 349521:HCH_RS15470
uniprot id: Q2SGN4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS00135
gene id: 349521:HCH_RS00135
uniprot id: Q2SQX2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

349521:HCH RS04170
gene id: 349521:HCH_RS04170
uniprot id: Q2SNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

349521:HCH RS09290
gene id: 349521:HCH_RS09290
uniprot id: Q2SKE2
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

349521:HCH RS15315
gene id: 349521:HCH_RS15315
uniprot id: Q2SGR6
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS10440
gene id: 349521:HCH_RS10440
uniprot id: Q2SJQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
messages: Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS29890
gene id: 349521:HCH_RS29890
uniprot id: Q2S7W3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS04160
gene id: 349521:HCH_RS04160
uniprot id: Q2SNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

349521:HCH RS10485
gene id: 349521:HCH_RS10485
uniprot id: Q2SJP9
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

349521:HCH RS16290
gene id: 349521:HCH_RS16290
uniprot id: Q2SG53
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

349521:HCH RS08960
gene id: 349521:HCH_RS08960
uniprot id: Q2SKL4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS04115
gene id: 349521:HCH_RS04115
uniprot id: Q2SNH6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS31895
gene id: 349521:HCH_RS31895
uniprot id: Q2S6P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

349521:HCH RS12405
gene id: 349521:HCH_RS12405
uniprot id: Q2SIJ6
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS23725
gene id: 349521:HCH_RS23725
uniprot id: Q2SBL8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

349521:HCH RS18180
gene id: 349521:HCH_RS18180
uniprot id: Q2SEY9
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

349521:HCH RS24440
gene id: 349521:HCH_RS24440
uniprot id: Q2SB66
names: Similarity
messages: Belongs to the PspA/IM30 family.

349521:HCH RS21335
gene id: 349521:HCH_RS21335
uniprot id: Q2SD22
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS11205
gene id: 349521:HCH_RS11205
uniprot id: Q2SJ95
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

349521:HCH RS00095
gene id: 349521:HCH_RS00095
uniprot id: Q2SQY0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349521:HCH RS32800
gene id: 349521:HCH_RS32800
uniprot id: Q2S886
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS20685
gene id: 349521:HCH_RS20685
uniprot id: Q2SDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

349521:HCH RS19710
gene id: 349521:HCH_RS19710
uniprot id: Q2SE06
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

349521:HCH RS14230
gene id: 349521:HCH_RS14230
uniprot id: Q2SHE8
names: Function
names: Similarity
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

349521:HCH RS02010
gene id: 349521:HCH_RS02010
uniprot id: Q2SPS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

349521:HCH RS24200
gene id: 349521:HCH_RS24200
uniprot id: Q2SBB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

349521:HCH RS09670
gene id: 349521:HCH_RS09670
uniprot id: Q2SK67
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS19515
gene id: 349521:HCH_RS19515
uniprot id: Q2SE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

349521:HCH RS25015
gene id: 349521:HCH_RS25015
uniprot id: Q2SAU3
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS22710
gene id: 349521:HCH_RS22710
uniprot id: Q2SC88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

349521:HCH RS07365
gene id: 349521:HCH_RS07365
uniprot id: Q2SLJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS00400
gene id: 349521:HCH_RS00400
uniprot id: Q2SQR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

349521:HCH RS08405
gene id: 349521:HCH_RS08405
uniprot id: Q2SKY0
names: Similarity
messages: Belongs to the WrbA family.

349521:HCH RS06510
gene id: 349521:HCH_RS06510
uniprot id: Q2SM16
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS27010
gene id: 349521:HCH_RS27010
uniprot id: Q2S9M0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

349521:HCH RS28250
gene id: 349521:HCH_RS28250
uniprot id: Q2S8W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

349521:HCH RS16795
gene id: 349521:HCH_RS16795
uniprot id: Q2SFT9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

349521:HCH RS24845
gene id: 349521:HCH_RS24845
uniprot id: Q2SAY1
names: Similarity
messages: Belongs to the PhzF family.

349521:HCH RS22440
gene id: 349521:HCH_RS22440
uniprot id: Q2SCE1
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

349521:HCH RS04785
gene id: 349521:HCH_RS04785
uniprot id: Q2SN33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

349521:HCH RS23795
gene id: 349521:HCH_RS23795
uniprot id: Q2SBK2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349521:HCH RS10620
gene id: 349521:HCH_RS10620
uniprot id: Q2SJL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

349521:HCH RS10625
gene id: 349521:HCH_RS10625
uniprot id: Q2SJL7
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

349521:HCH RS28595
gene id: 349521:HCH_RS28595
uniprot id: Q2S8N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

349521:HCH RS28700
gene id: 349521:HCH_RS28700
uniprot id: Q2S8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

349521:HCH RS09125
gene id: 349521:HCH_RS09125
uniprot id: Q2SKH7
names: Similarity
messages: Belongs to the FPG family.

349521:HCH RS04550
gene id: 349521:HCH_RS04550
uniprot id: Q2SN83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

349521:HCH RS09645
gene id: 349521:HCH_RS09645
uniprot id: Q2SK72
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

349521:HCH RS12165
gene id: 349521:HCH_RS12165
uniprot id: Q2SIP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

349521:HCH RS14710
gene id: 349521:HCH_RS14710
uniprot id: Q2SH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS20210
gene id: 349521:HCH_RS20210
uniprot id: Q2SDQ1
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

349521:HCH RS13370
gene id: 349521:HCH_RS13370
uniprot id: Q2SHY8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS26180
gene id: 349521:HCH_RS26180
uniprot id: Q2SA36
names: Similarity
messages: Belongs to the UPF0250 family.

349521:HCH RS19080
gene id: 349521:HCH_RS19080
uniprot id: Q2SEE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS03625
gene id: 349521:HCH_RS03625
uniprot id: Q2SNS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

349521:HCH RS29940
gene id: 349521:HCH_RS29940
uniprot id: Q2S7V3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS05865
gene id: 349521:HCH_RS05865
uniprot id: Q2SMF3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS18235
gene id: 349521:HCH_RS18235
uniprot id: Q2SEX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

349521:HCH RS22790
gene id: 349521:HCH_RS22790
uniprot id: Q2SC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349521:HCH RS27540
gene id: 349521:HCH_RS27540
uniprot id: Q2S9A3
names: Function
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

349521:HCH RS03855
gene id: 349521:HCH_RS03855
uniprot id: Q2SNN2
names: Function
messages: Repressor involved in choline regulation of the bet genes.
messages: Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine.

349521:HCH RS11095
gene id: 349521:HCH_RS11095
uniprot id: Q2SJC0
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

349521:HCH RS18515
gene id: 349521:HCH_RS18515
uniprot id: Q2SER3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

349521:HCH RS22245
gene id: 349521:HCH_RS22245
uniprot id: Q2SCI0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS10795
gene id: 349521:HCH_RS10795
uniprot id: Q2SJI3
names: Similarity
messages: Belongs to the peptidase S14 family.

349521:HCH RS23400
gene id: 349521:HCH_RS23400
uniprot id: Q2SBT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS01310
gene id: 349521:HCH_RS01310
uniprot id: Q2SQ73
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

349521:HCH RS19250
gene id: 349521:HCH_RS19250
uniprot id: Q2SEA7
names: Similarity
names: Subunit
messages: Belongs to the glutaredoxin family.
messages: Monomer.

349521:HCH RS22990
gene id: 349521:HCH_RS22990
uniprot id: Q2SC27
names: Similarity
messages: Belongs to the histone deacetylase family.

349521:HCH RS19075
gene id: 349521:HCH_RS19075
uniprot id: Q2SEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS18250
gene id: 349521:HCH_RS18250
uniprot id: Q2SEX5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

349521:HCH RS32865
gene id: 349521:HCH_RS32865
uniprot id: Q2S7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N-Me-Phe pilin family.
messages: Membrane

349521:HCH RS07900
gene id: 349521:HCH_RS07900
uniprot id: Q2SL84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

349521:HCH RS02605
gene id: 349521:HCH_RS02605
uniprot id: Q2SPF0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

349521:HCH RS01540
gene id: 349521:HCH_RS01540
uniprot id: Q2SQ24
names: Similarity
messages: Belongs to the CFA/CMAS family.

349521:HCH RS00245
gene id: 349521:HCH_RS00245
uniprot id: Q2SQU9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS05545
gene id: 349521:HCH_RS05545
uniprot id: Q2SML8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

349521:HCH RS26435
gene id: 349521:HCH_RS26435
uniprot id: Q2S9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

349521:HCH RS26750
gene id: 349521:HCH_RS26750
uniprot id: Q2S9S6
names: Similarity
messages: Belongs to the UPF0319 family.

349521:HCH RS28490
gene id: 349521:HCH_RS28490
uniprot id: Q2S8R1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS09795
gene id: 349521:HCH_RS09795
uniprot id: Q2SK40
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS04930
gene id: 349521:HCH_RS04930
uniprot id: Q2SN02
names: Subunit
messages: Homodimer.

349521:HCH RS22155
gene id: 349521:HCH_RS22155
uniprot id: Q2SCJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS05630
gene id: 349521:HCH_RS05630
uniprot id: Q2SMK1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS27295
gene id: 349521:HCH_RS27295
uniprot id: Q2S9F6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS08210
gene id: 349521:HCH_RS08210
uniprot id: Q2SL21
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS05275
gene id: 349521:HCH_RS05275
uniprot id: Q2SMS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

349521:HCH RS24265
gene id: 349521:HCH_RS24265
uniprot id: Q2SBA3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS09790
gene id: 349521:HCH_RS09790
uniprot id: Q2SK41
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349521:HCH RS28905
gene id: 349521:HCH_RS28905
uniprot id: Q2S8H7
names: Similarity
messages: Belongs to the YkuD family.

349521:HCH RS22430
gene id: 349521:HCH_RS22430
uniprot id: Q2SCE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

349521:HCH RS07830
gene id: 349521:HCH_RS07830
uniprot id: Q2SL99
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.

349521:HCH RS23510
gene id: 349521:HCH_RS23510
uniprot id: Q2SBR4
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

349521:HCH RS29460
gene id: 349521:HCH_RS29460
uniprot id: Q2S854
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

349521:HCH RS01010
gene id: 349521:HCH_RS01010
uniprot id: Q2SQD6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

349521:HCH RS00345
gene id: 349521:HCH_RS00345
uniprot id: Q2SQS9
names: Similarity
messages: Belongs to the HupF/HypC family.

349521:HCH RS20005
gene id: 349521:HCH_RS20005
uniprot id: Q2SDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

349521:HCH RS06880
gene id: 349521:HCH_RS06880
uniprot id: Q2SLU2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS03595
gene id: 349521:HCH_RS03595
uniprot id: Q2SNT5
names: Subcellular Location Annotation
messages: Cell inner membrane

349521:HCH RS11165
gene id: 349521:HCH_RS11165
uniprot id: Q2SJA3
names: Similarity
messages: Belongs to the glycosyl hydrolase 9 (cellulase E) family.

349521:HCH RS09910
gene id: 349521:HCH_RS09910
uniprot id: Q2SK19
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

349521:HCH RS10670
gene id: 349521:HCH_RS10670
uniprot id: Q2SJK7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

349521:HCH RS16625
gene id: 349521:HCH_RS16625
uniprot id: Q2SFX8
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

349521:HCH RS26905
gene id: 349521:HCH_RS26905
uniprot id: Q2S9P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

349521:HCH RS08140
gene id: 349521:HCH_RS08140
uniprot id: Q2SL35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

349521:HCH RS17940
gene id: 349521:HCH_RS17940
uniprot id: Q2SF39
names: Similarity
messages: Belongs to the SCO1/2 family.

349521:HCH RS05585
gene id: 349521:HCH_RS05585
uniprot id: Q2SML1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

349521:HCH RS27795
gene id: 349521:HCH_RS27795
uniprot id: Q2S948
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

349521:HCH RS19695
gene id: 349521:HCH_RS19695
uniprot id: Q2SE10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

349521:HCH RS06070
gene id: 349521:HCH_RS06070
uniprot id: Q2SMB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

349521:HCH RS14745
gene id: 349521:HCH_RS14745
uniprot id: Q2SH37
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

349521:HCH RS32750
gene id: 349521:HCH_RS32750
uniprot id: Q2SA98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS08410
gene id: 349521:HCH_RS08410
uniprot id: Q2SKX9
names: Similarity
messages: Belongs to the ArsC family.

349521:HCH RS03190
gene id: 349521:HCH_RS03190
uniprot id: Q2SP20
names: Similarity
messages: Belongs to the group II decarboxylase family.

349521:HCH RS00780
gene id: 349521:HCH_RS00780
uniprot id: Q2SQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS11620
gene id: 349521:HCH_RS11620
uniprot id: Q2SJ09
names: Similarity
messages: Belongs to the TPP enzyme family.

349521:HCH RS27955
gene id: 349521:HCH_RS27955
uniprot id: Q2S913
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

349521:HCH RS28210
gene id: 349521:HCH_RS28210
uniprot id: Q2S8X0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS22190
gene id: 349521:HCH_RS22190
uniprot id: Q2SCJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

349521:HCH RS11060
gene id: 349521:HCH_RS11060
uniprot id: Q2SJC8
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

349521:HCH RS18480
gene id: 349521:HCH_RS18480
uniprot id: Q2SES2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS03375
gene id: 349521:HCH_RS03375
uniprot id: Q2SNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

349521:HCH RS01260
gene id: 349521:HCH_RS01260
uniprot id: Q2SQ83
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

349521:HCH RS16155
gene id: 349521:HCH_RS16155
uniprot id: Q2SG81
names: Similarity
messages: Belongs to the NodU/CmcH family.

349521:HCH RS22450
gene id: 349521:HCH_RS22450
uniprot id: Q2SCD9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS22435
gene id: 349521:HCH_RS22435
uniprot id: Q2SCE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

349521:HCH RS10495
gene id: 349521:HCH_RS10495
uniprot id: Q2SJP7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

349521:HCH RS08185
gene id: 349521:HCH_RS08185
uniprot id: Q2SL26
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

349521:HCH RS08215
gene id: 349521:HCH_RS08215
uniprot id: Q2SL20
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

349521:HCH RS08395
gene id: 349521:HCH_RS08395
uniprot id: Q2SKY2
names: Similarity
messages: Belongs to the GSP E family.

349521:HCH RS04685
gene id: 349521:HCH_RS04685
uniprot id: Q2SN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

349521:HCH RS10155
gene id: 349521:HCH_RS10155
uniprot id: Q2SJX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

349521:HCH RS27050
gene id: 349521:HCH_RS27050
uniprot id: Q2S9L2
names: Similarity
messages: Belongs to the GARS family.

349521:HCH RS00405
gene id: 349521:HCH_RS00405
uniprot id: Q2SQR7
names: Similarity
messages: Belongs to the glycosyl hydrolase family 6.

349521:HCH RS23060
gene id: 349521:HCH_RS23060
uniprot id: Q2SC08
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

349521:HCH RS17035
gene id: 349521:HCH_RS17035
uniprot id: Q2SFN7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349521:HCH RS10705
gene id: 349521:HCH_RS10705
uniprot id: Q2SJK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

349521:HCH RS31675
gene id: 349521:HCH_RS31675
uniprot id: Q2S6T7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS23535
gene id: 349521:HCH_RS23535
uniprot id: Q2SBQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

349521:HCH RS15680
gene id: 349521:HCH_RS15680
uniprot id: Q2SGI9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

349521:HCH RS13585
gene id: 349521:HCH_RS13585
uniprot id: Q2SHT8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS21235
gene id: 349521:HCH_RS21235
uniprot id: Q2SD42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS14365
gene id: 349521:HCH_RS14365
uniprot id: Q2SHB8
names: Similarity
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.

349521:HCH RS03630
gene id: 349521:HCH_RS03630
uniprot id: Q2SNS7
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS26880
gene id: 349521:HCH_RS26880
uniprot id: Q2S9P8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

349521:HCH RS13450
gene id: 349521:HCH_RS13450
uniprot id: Q2SHW9
names: Similarity
messages: Belongs to the GST superfamily.

349521:HCH RS24010
gene id: 349521:HCH_RS24010
uniprot id: Q2SBF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

349521:HCH RS01850
gene id: 349521:HCH_RS01850
uniprot id: Q2SPV5
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

349521:HCH RS26730
gene id: 349521:HCH_RS26730
uniprot id: Q2S9T0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

349521:HCH RS05435
gene id: 349521:HCH_RS05435
uniprot id: Q2SMP0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS27980
gene id: 349521:HCH_RS27980
uniprot id: Q2S908
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

349521:HCH RS17825
gene id: 349521:HCH_RS17825
uniprot id: Q2SF65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS26400
gene id: 349521:HCH_RS26400
uniprot id: Q2S9Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

349521:HCH RS20495
gene id: 349521:HCH_RS20495
uniprot id: Q2SDJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

349521:HCH RS27895
gene id: 349521:HCH_RS27895
uniprot id: Q2S925
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

349521:HCH RS21945
gene id: 349521:HCH_RS21945
uniprot id: Q2SCN8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

349521:HCH RS29225
gene id: 349521:HCH_RS29225
uniprot id: Q2S8A7
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

349521:HCH RS26735
gene id: 349521:HCH_RS26735
uniprot id: Q2S9S9
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

349521:HCH RS23915
gene id: 349521:HCH_RS23915
uniprot id: Q2SBH7
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS25905
gene id: 349521:HCH_RS25905
uniprot id: Q2SA96
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS27450
gene id: 349521:HCH_RS27450
uniprot id: Q2S9C1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

349521:HCH RS23550
gene id: 349521:HCH_RS23550
uniprot id: Q2SBQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

349521:HCH RS04310
gene id: 349521:HCH_RS04310
uniprot id: Q2SND4
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

349521:HCH RS11600
gene id: 349521:HCH_RS11600
uniprot id: Q2SJ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS31525
gene id: 349521:HCH_RS31525
uniprot id: Q2S6X3
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

349521:HCH RS08350
gene id: 349521:HCH_RS08350
uniprot id: Q2SKZ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

349521:HCH RS06105
gene id: 349521:HCH_RS06105
uniprot id: Q2SMA5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

349521:HCH RS20690
gene id: 349521:HCH_RS20690
uniprot id: Q2SDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

349521:HCH RS26485
gene id: 349521:HCH_RS26485
uniprot id: Q2S9X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

349521:HCH RS28335
gene id: 349521:HCH_RS28335
uniprot id: Q2S8U3
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

349521:HCH RS05665
gene id: 349521:HCH_RS05665
uniprot id: Q2SMJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

349521:HCH RS16955
gene id: 349521:HCH_RS16955
uniprot id: Q2SFQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS08420
gene id: 349521:HCH_RS08420
uniprot id: Q2SKX6
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS04610
gene id: 349521:HCH_RS04610
uniprot id: Q2SN69
names: Similarity
messages: Belongs to the UPF0758 family.

349521:HCH RS08030
gene id: 349521:HCH_RS08030
uniprot id: Q2SL57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

349521:HCH RS17560
gene id: 349521:HCH_RS17560
uniprot id: Q2SFC8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

349521:HCH RS15105
gene id: 349521:HCH_RS15105
uniprot id: Q2SGV7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

349521:HCH RS07690
gene id: 349521:HCH_RS07690
uniprot id: Q2SLC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS10615
gene id: 349521:HCH_RS10615
uniprot id: Q2SJL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

349521:HCH RS27915
gene id: 349521:HCH_RS27915
uniprot id: Q2S921
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

349521:HCH RS27550
gene id: 349521:HCH_RS27550
uniprot id: Q2S9A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

349521:HCH RS26575
gene id: 349521:HCH_RS26575
uniprot id: Q2S9W1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

349521:HCH RS09655
gene id: 349521:HCH_RS09655
uniprot id: Q2SK70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class II aldolase/RraA-like family.
messages: Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
messages: Divalent metal cation.
messages: Homotrimer.

349521:HCH RS06630
gene id: 349521:HCH_RS06630
uniprot id: Q2SLZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS26920
gene id: 349521:HCH_RS26920
uniprot id: Q2S9P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

349521:HCH RS28615
gene id: 349521:HCH_RS28615
uniprot id: Q2S8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

349521:HCH RS07500
gene id: 349521:HCH_RS07500
uniprot id: Q2SLG5
names: Similarity
messages: Belongs to the asparagine synthetase family.

349521:HCH RS08695
gene id: 349521:HCH_RS08695
uniprot id: Q2SKS2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

349521:HCH RS16320
gene id: 349521:HCH_RS16320
uniprot id: Q2SG43
names: Similarity
messages: Belongs to the diaminopimelate epimerase family.

349521:HCH RS11450
gene id: 349521:HCH_RS11450
uniprot id: Q2SJ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

349521:HCH RS10925
gene id: 349521:HCH_RS10925
uniprot id: Q2SJF6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

349521:HCH RS25900
gene id: 349521:HCH_RS25900
uniprot id: Q2SA97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS28035
gene id: 349521:HCH_RS28035
uniprot id: Q2S8Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

349521:HCH RS27160
gene id: 349521:HCH_RS27160
uniprot id: Q2S9I7
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS01005
gene id: 349521:HCH_RS01005
uniprot id: Q2SQD7
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

349521:HCH RS04605
gene id: 349521:HCH_RS04605
uniprot id: Q2SN70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

349521:HCH RS14530
gene id: 349521:HCH_RS14530
uniprot id: Q2SH79
names: Similarity
messages: Belongs to the YciI family.

349521:HCH RS16495
gene id: 349521:HCH_RS16495
uniprot id: Q2SG04
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS29200
gene id: 349521:HCH_RS29200
uniprot id: Q2S8B2
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

349521:HCH RS29355
gene id: 349521:HCH_RS29355
uniprot id: Q2S877
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS24840
gene id: 349521:HCH_RS24840
uniprot id: Q2SAY2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS14410
gene id: 349521:HCH_RS14410
uniprot id: Q2SHA6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

349521:HCH RS00515
gene id: 349521:HCH_RS00515
uniprot id: Q2SQP3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

349521:HCH RS21920
gene id: 349521:HCH_RS21920
uniprot id: Q2SCP5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

349521:HCH RS12105
gene id: 349521:HCH_RS12105
uniprot id: Q2SIQ8
names: Similarity
messages: Belongs to the YkuD family.

349521:HCH RS18700
gene id: 349521:HCH_RS18700
uniprot id: Q2SEM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS24780
gene id: 349521:HCH_RS24780
uniprot id: Q2SAZ6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

349521:HCH RS27655
gene id: 349521:HCH_RS27655
uniprot id: Q2S978
names: Similarity
messages: Belongs to the GSP E family.

349521:HCH RS01890
gene id: 349521:HCH_RS01890
uniprot id: Q2SPU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS06265
gene id: 349521:HCH_RS06265
uniprot id: Q2SM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS03360
gene id: 349521:HCH_RS03360
uniprot id: Q2SNY1
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

349521:HCH RS01895
gene id: 349521:HCH_RS01895
uniprot id: Q2SPU6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
messages: Membrane

349521:HCH RS28970
gene id: 349521:HCH_RS28970
uniprot id: Q2S8G4
names: Similarity
messages: Belongs to the GST superfamily.

349521:HCH RS26830
gene id: 349521:HCH_RS26830
uniprot id: Q2S9Q8
names: Similarity
messages: Belongs to the glutamate synthase family.

349521:HCH RS21555
gene id: 349521:HCH_RS21555
uniprot id: Q2SCX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

349521:HCH RS31515
gene id: 349521:HCH_RS31515
uniprot id: Q2S6X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.

349521:HCH RS25990
gene id: 349521:HCH_RS25990
uniprot id: Q2SA77
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS27490
gene id: 349521:HCH_RS27490
uniprot id: Q2S9B3
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

349521:HCH RS01045
gene id: 349521:HCH_RS01045
uniprot id: Q2SQC8
names: Similarity
messages: Belongs to the GSP E family.

349521:HCH RS19505
gene id: 349521:HCH_RS19505
uniprot id: Q2SE53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

349521:HCH RS05015
gene id: 349521:HCH_RS05015
uniprot id: Q2SMY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

349521:HCH RS29035
gene id: 349521:HCH_RS29035
uniprot id: Q2S8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS20025
gene id: 349521:HCH_RS20025
uniprot id: Q2SDU2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

349521:HCH RS02380
gene id: 349521:HCH_RS02380
uniprot id: Q2SPJ7
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

349521:HCH RS28655
gene id: 349521:HCH_RS28655
uniprot id: Q2S8M5
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

349521:HCH RS19460
gene id: 349521:HCH_RS19460
uniprot id: Q2SE62
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS01885
gene id: 349521:HCH_RS01885
uniprot id: Q2SPU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS34545
gene id: 349521:HCH_RS34545
uniprot id: Q2SN16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

349521:HCH RS12230
gene id: 349521:HCH_RS12230
uniprot id: Q2SIN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

349521:HCH RS02525
gene id: 349521:HCH_RS02525
uniprot id: Q2SPG7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

349521:HCH RS27330
gene id: 349521:HCH_RS27330
uniprot id: Q2S9E9
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

349521:HCH RS22390
gene id: 349521:HCH_RS22390
uniprot id: Q2SCF1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

349521:HCH RS08575
gene id: 349521:HCH_RS08575
uniprot id: Q2SKU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

349521:HCH RS09835
gene id: 349521:HCH_RS09835
uniprot id: Q2SK35
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

349521:HCH RS28885
gene id: 349521:HCH_RS28885
uniprot id: Q2S8I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

349521:HCH RS27835
gene id: 349521:HCH_RS27835
uniprot id: Q2S938
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

349521:HCH RS08155
gene id: 349521:HCH_RS08155
uniprot id: Q2SL32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

349521:HCH RS29165
gene id: 349521:HCH_RS29165
uniprot id: Q2S8B9
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

349521:HCH RS10710
gene id: 349521:HCH_RS10710
uniprot id: Q2SJJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

349521:HCH RS17375
gene id: 349521:HCH_RS17375
uniprot id: Q2SFG5
names: Similarity
messages: Belongs to the AHA1 family.

349521:HCH RS06790
gene id: 349521:HCH_RS06790
uniprot id: Q2SLW2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

349521:HCH RS00140
gene id: 349521:HCH_RS00140
uniprot id: Q2SQX1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

349521:HCH RS24060
gene id: 349521:HCH_RS24060
uniprot id: Q2SBE5
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

349521:HCH RS24395
gene id: 349521:HCH_RS24395
uniprot id: Q2SB76
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS20480
gene id: 349521:HCH_RS20480
uniprot id: Q2SDJ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349521:HCH RS09930
gene id: 349521:HCH_RS09930
uniprot id: Q2SK14
names: Similarity
messages: Belongs to the VgrG protein family.

349521:HCH RS23835
gene id: 349521:HCH_RS23835
uniprot id: Q2SBJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

349521:HCH RS18070
gene id: 349521:HCH_RS18070
uniprot id: Q2SF13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

349521:HCH RS10535
gene id: 349521:HCH_RS10535
uniprot id: Q2SJN9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS27600
gene id: 349521:HCH_RS27600
uniprot id: Q2S989
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS21605
gene id: 349521:HCH_RS21605
uniprot id: Q2SCW4
names: Similarity
messages: Belongs to the histone deacetylase family.

349521:HCH RS14210
gene id: 349521:HCH_RS14210
uniprot id: Q2SHF2
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS20990
gene id: 349521:HCH_RS20990
uniprot id: Q2SD96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS26320
gene id: 349521:HCH_RS26320
uniprot id: Q2SA08
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

349521:HCH RS02610
gene id: 349521:HCH_RS02610
uniprot id: Q2SPE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

349521:HCH RS01965
gene id: 349521:HCH_RS01965
uniprot id: Q2SPT2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349521:HCH RS27230
gene id: 349521:HCH_RS27230
uniprot id: Q2S9H0
names: Similarity
messages: Belongs to the asparagine synthetase family.

349521:HCH RS23260
gene id: 349521:HCH_RS23260
uniprot id: Q2SBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

349521:HCH RS23410
gene id: 349521:HCH_RS23410
uniprot id: Q2SBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

349521:HCH RS04290
gene id: 349521:HCH_RS04290
uniprot id: Q2SND8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS00185
gene id: 349521:HCH_RS00185
uniprot id: Q2SQW1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

349521:HCH RS04810
gene id: 349521:HCH_RS04810
uniprot id: Q2SN28
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

349521:HCH RS31330
gene id: 349521:HCH_RS31330
uniprot id: Q2S716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS07850
gene id: 349521:HCH_RS07850
uniprot id: Q2SL94
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

349521:HCH RS15990
gene id: 349521:HCH_RS15990
uniprot id: Q2SGB9
names: Similarity
messages: Belongs to the aerolysin family.

349521:HCH RS05440
gene id: 349521:HCH_RS05440
uniprot id: Q2SMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
messages: Cell inner membrane
messages: Homodimer. Part of the tripartite efflux system MacAB-TolC, which is composed of an inner membrane transporter, MacB, a periplasmic membrane fusion protein, MacA, and an outer membrane component, TolC. The complex forms a large protein conduit and can translocate molecules across both the inner and outer membranes. Interacts with MacA.
messages: Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.

349521:HCH RS20200
gene id: 349521:HCH_RS20200
uniprot id: Q2SDQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

349521:HCH RS12750
gene id: 349521:HCH_RS12750
uniprot id: Q2SIB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

349521:HCH RS24820
gene id: 349521:HCH_RS24820
uniprot id: Q2SAY5
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: host cytosol

349521:HCH RS26490
gene id: 349521:HCH_RS26490
uniprot id: Q2S9X4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

349521:HCH RS08895
gene id: 349521:HCH_RS08895
uniprot id: Q2SKM9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS24755
gene id: 349521:HCH_RS24755
uniprot id: Q2SB02
names: Similarity
messages: Belongs to the pirin family.

349521:HCH RS32360
gene id: 349521:HCH_RS32360
uniprot id: Q2SHN6
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

349521:HCH RS02480
gene id: 349521:HCH_RS02480
uniprot id: Q2SPH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349521:HCH RS03725
gene id: 349521:HCH_RS03725
uniprot id: Q2SNQ8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

349521:HCH RS27950
gene id: 349521:HCH_RS27950
uniprot id: Q2S914
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

349521:HCH RS08040
gene id: 349521:HCH_RS08040
uniprot id: Q2SL55
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

349521:HCH RS06505
gene id: 349521:HCH_RS06505
uniprot id: Q2SM17
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

349521:HCH RS09700
gene id: 349521:HCH_RS09700
uniprot id: Q2SK60
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

349521:HCH RS26325
gene id: 349521:HCH_RS26325
uniprot id: Q2SA07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

349521:HCH RS07695
gene id: 349521:HCH_RS07695
uniprot id: Q2SLC3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

349521:HCH RS27390
gene id: 349521:HCH_RS27390
uniprot id: Q2S9D5
names: Similarity
messages: Belongs to the UPF0502 family.

349521:HCH RS22970
gene id: 349521:HCH_RS22970
uniprot id: Q2SC31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane

349521:HCH RS23195
gene id: 349521:HCH_RS23195
uniprot id: Q2SBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CheZ family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).

349521:HCH RS19245
gene id: 349521:HCH_RS19245
uniprot id: Q2SEA8
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

349521:HCH RS03645
gene id: 349521:HCH_RS03645
uniprot id: Q2SNS4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

349521:HCH RS21710
gene id: 349521:HCH_RS21710
uniprot id: Q2SCU3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

349521:HCH RS02905
gene id: 349521:HCH_RS02905
uniprot id: Q2SP85
names: Similarity
messages: Belongs to the HIBADH-related family.

349521:HCH RS11425
gene id: 349521:HCH_RS11425
uniprot id: Q2SJ48
names: Similarity
messages: Belongs to the transglycosylase Slt family.

349521:HCH RS03950
gene id: 349521:HCH_RS03950
uniprot id: Q2SNL2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

349521:HCH RS08825
gene id: 349521:HCH_RS08825
uniprot id: Q2SKP4
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

349521:HCH RS14425
gene id: 349521:HCH_RS14425
uniprot id: Q2SHA1
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

349521:HCH RS29290
gene id: 349521:HCH_RS29290
uniprot id: Q2S890
names: Similarity
messages: Belongs to the prespore-cell-inducing factor family.

349521:HCH RS12120
gene id: 349521:HCH_RS12120
uniprot id: Q2SIQ5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS27890
gene id: 349521:HCH_RS27890
uniprot id: Q2S926
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

349521:HCH RS26745
gene id: 349521:HCH_RS26745
uniprot id: Q2S9S7
names: Similarity
messages: Belongs to the MEMO1 family.

349521:HCH RS11875
gene id: 349521:HCH_RS11875
uniprot id: Q2SIW2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

349521:HCH RS07510
gene id: 349521:HCH_RS07510
uniprot id: Q2SLG3
names: Similarity
messages: Belongs to the peptidase M42 family.

349521:HCH RS31905
gene id: 349521:HCH_RS31905
uniprot id: Q2S6P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

349521:HCH RS23530
gene id: 349521:HCH_RS23530
uniprot id: Q2SBR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

349521:HCH RS26770
gene id: 349521:HCH_RS26770
uniprot id: Q2S9S0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

349521:HCH RS27860
gene id: 349521:HCH_RS27860
uniprot id: Q2S932
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

349521:HCH RS12140
gene id: 349521:HCH_RS12140
uniprot id: Q2SIQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

349521:HCH RS00485
gene id: 349521:HCH_RS00485
uniprot id: Q2SQP9
names: Similarity
messages: Belongs to the peptidase A31 family.

349521:HCH RS13230
gene id: 349521:HCH_RS13230
uniprot id: Q2SI17
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS13425
gene id: 349521:HCH_RS13425
uniprot id: Q2SHX4
names: Similarity
messages: Belongs to the peptidase S8 family.

349521:HCH RS12030
gene id: 349521:HCH_RS12030
uniprot id: Q2SIS7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

349521:HCH RS31965
gene id: 349521:HCH_RS31965
uniprot id: Q2S6M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS04675
gene id: 349521:HCH_RS04675
uniprot id: Q2SN56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

349521:HCH RS04795
gene id: 349521:HCH_RS04795
uniprot id: Q2SN31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

349521:HCH RS13255
gene id: 349521:HCH_RS13255
uniprot id: Q2SI12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ZnuC), two transmembrane proteins (ZnuB) and a solute-binding protein (ZnuA).

349521:HCH RS29855
gene id: 349521:HCH_RS29855
uniprot id: Q2S7X1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS19545
gene id: 349521:HCH_RS19545
uniprot id: Q2SE45
names: Similarity
messages: Belongs to the Dps family.

349521:HCH RS00020
gene id: 349521:HCH_RS00020
uniprot id: Q2SQZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS24055
gene id: 349521:HCH_RS24055
uniprot id: Q2SBE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

349521:HCH RS04570
gene id: 349521:HCH_RS04570
uniprot id: Q2SN78
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

349521:HCH RS04180
gene id: 349521:HCH_RS04180
uniprot id: Q2SNG2
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS16400
gene id: 349521:HCH_RS16400
uniprot id: Q2SG27
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

349521:HCH RS28285
gene id: 349521:HCH_RS28285
uniprot id: Q2S8V4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

349521:HCH RS20660
gene id: 349521:HCH_RS20660
uniprot id: Q2SDG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

349521:HCH RS04165
gene id: 349521:HCH_RS04165
uniprot id: Q2SNG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

349521:HCH RS12155
gene id: 349521:HCH_RS12155
uniprot id: Q2SIP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

349521:HCH RS24215
gene id: 349521:HCH_RS24215
uniprot id: Q2SBB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

349521:HCH RS27425
gene id: 349521:HCH_RS27425
uniprot id: Q2S9C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

349521:HCH RS18270
gene id: 349521:HCH_RS18270
uniprot id: Q2SEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

349521:HCH RS22100
gene id: 349521:HCH_RS22100
uniprot id: Q2SCK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

349521:HCH RS03765
gene id: 349521:HCH_RS03765
uniprot id: Q2SNQ0
names: Similarity
messages: Belongs to the polysaccharide lyase 3 family.

349521:HCH RS08565
gene id: 349521:HCH_RS08565
uniprot id: Q2SKV0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

349521:HCH RS05480
gene id: 349521:HCH_RS05480
uniprot id: Q2SMN1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS08500
gene id: 349521:HCH_RS08500
uniprot id: Q2SKW4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

349521:HCH RS07270
gene id: 349521:HCH_RS07270
uniprot id: Q2SLL3
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

349521:HCH RS02085
gene id: 349521:HCH_RS02085
uniprot id: Q2SPQ7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS03350
gene id: 349521:HCH_RS03350
uniprot id: Q2SNY3
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

349521:HCH RS29145
gene id: 349521:HCH_RS29145
uniprot id: Q2S8C3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

349521:HCH RS22380
gene id: 349521:HCH_RS22380
uniprot id: Q2SCF3
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

349521:HCH RS26570
gene id: 349521:HCH_RS26570
uniprot id: Q2S9W2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MsrQ family.
messages: Binds 1 FMN per subunit.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Cell inner membrane
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Membrane
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.

349521:HCH RS08060
gene id: 349521:HCH_RS08060
uniprot id: Q2SL51
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

349521:HCH RS18635
gene id: 349521:HCH_RS18635
uniprot id: Q2SEN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349521:HCH RS35060
gene id: 349521:HCH_RS35060
uniprot id: Q2SBN7
names: Subcellular Location Annotation
messages: Cytoplasm

349521:HCH RS06815
gene id: 349521:HCH_RS06815
uniprot id: Q2SLV7
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

349521:HCH RS26780
gene id: 349521:HCH_RS26780
uniprot id: Q2S9R8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

349521:HCH RS04040
gene id: 349521:HCH_RS04040
uniprot id: Q2SNJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS23310
gene id: 349521:HCH_RS23310
uniprot id: Q2SBV2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

349521:HCH RS15120
gene id: 349521:HCH_RS15120
uniprot id: Q2SGV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349521:HCH RS03140
gene id: 349521:HCH_RS03140
uniprot id: Q2SP32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS12220
gene id: 349521:HCH_RS12220
uniprot id: Q2SIN4
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

349521:HCH RS04790
gene id: 349521:HCH_RS04790
uniprot id: Q2SN32
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS23805
gene id: 349521:HCH_RS23805
uniprot id: Q2SBK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZapG family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS08760
gene id: 349521:HCH_RS08760
uniprot id: Q2SKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

349521:HCH RS29010
gene id: 349521:HCH_RS29010
uniprot id: Q2S8F5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS09945
gene id: 349521:HCH_RS09945
uniprot id: Q2SK11
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS00575
gene id: 349521:HCH_RS00575
uniprot id: Q2SQN0
names: Similarity
messages: Belongs to the EndA/NucM nuclease family.

349521:HCH RS27830
gene id: 349521:HCH_RS27830
uniprot id: Q2S939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

349521:HCH RS31365
gene id: 349521:HCH_RS31365
uniprot id: Q2S707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS24100
gene id: 349521:HCH_RS24100
uniprot id: Q2SBD7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

349521:HCH RS21350
gene id: 349521:HCH_RS21350
uniprot id: Q2SD19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

349521:HCH RS12150
gene id: 349521:HCH_RS12150
uniprot id: Q2SIP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
messages: The residue potentially involved in the covalent binding of FMN is a Ser instead of a Thr.

349521:HCH RS12725
gene id: 349521:HCH_RS12725
uniprot id: Q2SIC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

349521:HCH RS16140
gene id: 349521:HCH_RS16140
uniprot id: Q2SG84
names: Similarity
messages: Belongs to the cytochrome P450 family.

349521:HCH RS28670
gene id: 349521:HCH_RS28670
uniprot id: Q2S8M2
names: Similarity
messages: Belongs to the UPF0235 family.

349521:HCH RS01095
gene id: 349521:HCH_RS01095
uniprot id: Q2SQB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SelU family.
messages: Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
messages: Monomer.

349521:HCH RS17925
gene id: 349521:HCH_RS17925
uniprot id: Q2SF42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

349521:HCH RS10000
gene id: 349521:HCH_RS10000
uniprot id: Q2SJZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

349521:HCH RS23860
gene id: 349521:HCH_RS23860
uniprot id: Q2SBI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

349521:HCH RS23520
gene id: 349521:HCH_RS23520
uniprot id: Q2SBR2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

349521:HCH RS08865
gene id: 349521:HCH_RS08865
uniprot id: Q2SKN6
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
messages: Protects the bacterial cell from host peptidases.

349521:HCH RS04320
gene id: 349521:HCH_RS04320
uniprot id: Q2SND2
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

349521:HCH RS21810
gene id: 349521:HCH_RS21810
uniprot id: Q2SCS4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS25660
gene id: 349521:HCH_RS25660
uniprot id: Q2SAF0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

349521:HCH RS00650
gene id: 349521:HCH_RS00650
uniprot id: Q2SQL4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

349521:HCH RS31325
gene id: 349521:HCH_RS31325
uniprot id: Q2S717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

349521:HCH RS23910
gene id: 349521:HCH_RS23910
uniprot id: Q2SBH8
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

349521:HCH RS03195
gene id: 349521:HCH_RS03195
uniprot id: Q2SP19
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS21610
gene id: 349521:HCH_RS21610
uniprot id: Q2SCW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

349521:HCH RS21065
gene id: 349521:HCH_RS21065
uniprot id: Q2SD78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS10110
gene id: 349521:HCH_RS10110
uniprot id: Q2SJX9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS07675
gene id: 349521:HCH_RS07675
uniprot id: Q2SLC8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS11430
gene id: 349521:HCH_RS11430
uniprot id: Q2SJ47
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

349521:HCH RS07085
gene id: 349521:HCH_RS07085
uniprot id: Q2SLQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

349521:HCH RS08180
gene id: 349521:HCH_RS08180
uniprot id: Q2SL27
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

349521:HCH RS31740
gene id: 349521:HCH_RS31740
uniprot id: Q2S6S3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349521:HCH RS24890
gene id: 349521:HCH_RS24890
uniprot id: Q2SAX1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

349521:HCH RS08580
gene id: 349521:HCH_RS08580
uniprot id: Q2SKU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

349521:HCH RS02560
gene id: 349521:HCH_RS02560
uniprot id: Q2SPF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

349521:HCH RS22020
gene id: 349521:HCH_RS22020
uniprot id: Q2SCM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

349521:HCH RS01905
gene id: 349521:HCH_RS01905
uniprot id: Q2SPU4
names: Similarity
messages: Belongs to the peptidase C40 family.

349521:HCH RS22400
gene id: 349521:HCH_RS22400
uniprot id: Q2SCE9
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

349521:HCH RS27975
gene id: 349521:HCH_RS27975
uniprot id: Q2S909
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

349521:HCH RS09255
gene id: 349521:HCH_RS09255
uniprot id: Q2SKE9
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS23800
gene id: 349521:HCH_RS23800
uniprot id: Q2SBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AFG1 ATPase family. ZapE subfamily.
messages: Cytoplasm
messages: Interacts with FtsZ.
messages: Reduces the stability of FtsZ polymers in the presence of ATP.

349521:HCH RS30385
gene id: 349521:HCH_RS30385
uniprot id: Q2S7L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

349521:HCH RS22095
gene id: 349521:HCH_RS22095
uniprot id: Q2SCL1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

349521:HCH RS00100
gene id: 349521:HCH_RS00100
uniprot id: Q2SQX9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349521:HCH RS28265
gene id: 349521:HCH_RS28265
uniprot id: Q2S8V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

349521:HCH RS07845
gene id: 349521:HCH_RS07845
uniprot id: Q2SL95
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

349521:HCH RS22345
gene id: 349521:HCH_RS22345
uniprot id: Q2SCG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

349521:HCH RS23620
gene id: 349521:HCH_RS23620
uniprot id: Q2SBP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

349521:HCH RS15310
gene id: 349521:HCH_RS15310
uniprot id: Q2SGR7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349521:HCH RS07480
gene id: 349521:HCH_RS07480
uniprot id: Q2SLG9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS21535
gene id: 349521:HCH_RS21535
uniprot id: Q2SCX8
names: Similarity
messages: Belongs to the UPF0246 family.

349521:HCH RS10530
gene id: 349521:HCH_RS10530
uniprot id: Q2SJP0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS26775
gene id: 349521:HCH_RS26775
uniprot id: Q2S9R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

349521:HCH RS31420
gene id: 349521:HCH_RS31420
uniprot id: Q2S6Z5
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

349521:HCH RS28935
gene id: 349521:HCH_RS28935
uniprot id: Q2S8H1
names: Similarity
messages: Belongs to the Dps family.

349521:HCH RS29625
gene id: 349521:HCH_RS29625
uniprot id: Q2S819
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS13415
gene id: 349521:HCH_RS13415
uniprot id: Q2SHX6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS03390
gene id: 349521:HCH_RS03390
uniprot id: Q2SNX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS13460
gene id: 349521:HCH_RS13460
uniprot id: Q2SHW7
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

349521:HCH RS14805
gene id: 349521:HCH_RS14805
uniprot id: Q2SH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS04275
gene id: 349521:HCH_RS04275
uniprot id: Q2SNE1
names: Similarity
messages: Belongs to the PspA/IM30 family.

349521:HCH RS28470
gene id: 349521:HCH_RS28470
uniprot id: Q2S8R5
names: Similarity
messages: Belongs to the RutC family.

349521:HCH RS19605
gene id: 349521:HCH_RS19605
uniprot id: Q2SE31
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

349521:HCH RS22030
gene id: 349521:HCH_RS22030
uniprot id: Q2SCM2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48 family. BepA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
messages: Periplasm

349521:HCH RS17945
gene id: 349521:HCH_RS17945
uniprot id: Q2SF38
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS18245
gene id: 349521:HCH_RS18245
uniprot id: Q2SEX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

349521:HCH RS31500
gene id: 349521:HCH_RS31500
uniprot id: Q2S6X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS30180
gene id: 349521:HCH_RS30180
uniprot id: Q2S7Q4
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS19900
gene id: 349521:HCH_RS19900
uniprot id: Q2SDW6
names: Similarity
messages: Belongs to the YfgM family.

349521:HCH RS01505
gene id: 349521:HCH_RS01505
uniprot id: Q2SQ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

349521:HCH RS09320
gene id: 349521:HCH_RS09320
uniprot id: Q2SKD6
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS24160
gene id: 349521:HCH_RS24160
uniprot id: Q2SBC5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

349521:HCH RS17935
gene id: 349521:HCH_RS17935
uniprot id: Q2SF40
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349521:HCH RS04190
gene id: 349521:HCH_RS04190
uniprot id: Q2SNG0
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS22350
gene id: 349521:HCH_RS22350
uniprot id: Q2SCF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

349521:HCH RS06750
gene id: 349521:HCH_RS06750
uniprot id: Q2SLX0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

349521:HCH RS12095
gene id: 349521:HCH_RS12095
uniprot id: Q2SIR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

349521:HCH RS26200
gene id: 349521:HCH_RS26200
uniprot id: Q2SA32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

349521:HCH RS11020
gene id: 349521:HCH_RS11020
uniprot id: Q2SJD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS20535
gene id: 349521:HCH_RS20535
uniprot id: Q2SDI6
names: Similarity
messages: Belongs to the peptidase M1 family.

349521:HCH RS07755
gene id: 349521:HCH_RS07755
uniprot id: Q2SLB2
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

349521:HCH RS28860
gene id: 349521:HCH_RS28860
uniprot id: Q2S8I4
names: Similarity
messages: Belongs to the DprA/Smf family.

349521:HCH RS20930
gene id: 349521:HCH_RS20930
uniprot id: Q2SDB0
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS09195
gene id: 349521:HCH_RS09195
uniprot id: Q2SKG3
names: Similarity
messages: Belongs to the thioesterase family.

349521:HCH RS20010
gene id: 349521:HCH_RS20010
uniprot id: Q2SDU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

349521:HCH RS00025
gene id: 349521:HCH_RS00025
uniprot id: Q2SQZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

349521:HCH RS06590
gene id: 349521:HCH_RS06590
uniprot id: Q2SM01
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS27735
gene id: 349521:HCH_RS27735
uniprot id: Q2S962
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

349521:HCH RS23830
gene id: 349521:HCH_RS23830
uniprot id: Q2SBJ5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

349521:HCH RS07615
gene id: 349521:HCH_RS07615
uniprot id: Q2SLD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

349521:HCH RS27855
gene id: 349521:HCH_RS27855
uniprot id: Q2S934
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

349521:HCH RS25045
gene id: 349521:HCH_RS25045
uniprot id: Q2SAT5
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

349521:HCH RS14965
gene id: 349521:HCH_RS14965
uniprot id: Q2SGY8
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS01365
gene id: 349521:HCH_RS01365
uniprot id: Q2SQ62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

349521:HCH RS11935
gene id: 349521:HCH_RS11935
uniprot id: Q2SIV0
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

349521:HCH RS28990
gene id: 349521:HCH_RS28990
uniprot id: Q2S8F9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

349521:HCH RS10520
gene id: 349521:HCH_RS10520
uniprot id: Q2SJP2
names: Similarity
messages: Belongs to the BMP lipoprotein family.

349521:HCH RS31970
gene id: 349521:HCH_RS31970
uniprot id: Q2S6M6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

349521:HCH RS27910
gene id: 349521:HCH_RS27910
uniprot id: Q2S922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

349521:HCH RS10340
gene id: 349521:HCH_RS10340
uniprot id: Q2SJT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS29795
gene id: 349521:HCH_RS29795
uniprot id: Q2S7Y3
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

349521:HCH RS05795
gene id: 349521:HCH_RS05795
uniprot id: Q2SMG7
names: Similarity
messages: Belongs to the peptidase S11 family.

349521:HCH RS31660
gene id: 349521:HCH_RS31660
uniprot id: Q2S6U1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

349521:HCH RS04715
gene id: 349521:HCH_RS04715
uniprot id: Q2SN47
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

349521:HCH RS08845
gene id: 349521:HCH_RS08845
uniprot id: Q2SKP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

349521:HCH RS24165
gene id: 349521:HCH_RS24165
uniprot id: Q2SBC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

349521:HCH RS25685
gene id: 349521:HCH_RS25685
uniprot id: Q2SAE6
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

349521:HCH RS27785
gene id: 349521:HCH_RS27785
uniprot id: Q2S950
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS10060
gene id: 349521:HCH_RS10060
uniprot id: Q2SJZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

349521:HCH RS12035
gene id: 349521:HCH_RS12035
uniprot id: Q2SIS4
names: Cofactor
messages: Binds 1 Mg(2+) ion per subunit.

349521:HCH RS29705
gene id: 349521:HCH_RS29705
uniprot id: Q2S802
names: Similarity
messages: Belongs to the PspA/IM30 family.

349521:HCH RS02455
gene id: 349521:HCH_RS02455
uniprot id: Q2SPI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

349521:HCH RS19890
gene id: 349521:HCH_RS19890
uniprot id: Q2SDW8
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

349521:HCH RS14585
gene id: 349521:HCH_RS14585
uniprot id: Q2SH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS26800
gene id: 349521:HCH_RS26800
uniprot id: Q2S9R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS30010
gene id: 349521:HCH_RS30010
uniprot id: Q2S7T9
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

349521:HCH RS20220
gene id: 349521:HCH_RS20220
uniprot id: Q2SDP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

349521:HCH RS26480
gene id: 349521:HCH_RS26480
uniprot id: Q2S9X6
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

349521:HCH RS19740
gene id: 349521:HCH_RS19740
uniprot id: Q2SE00
names: Similarity
names: Subunit
messages: Belongs to the Ahb/Nir family.
messages: Probably forms a complex composed of NirD, NirL, NirG and NirH. All proteins are required for the total conversion of siroheme to didecarboxysiroheme.

349521:HCH RS01295
gene id: 349521:HCH_RS01295
uniprot id: Q2SQ76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.

349521:HCH RS21360
gene id: 349521:HCH_RS21360
uniprot id: Q2SD17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

349521:HCH RS21265
gene id: 349521:HCH_RS21265
uniprot id: Q2SD36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

349521:HCH RS17910
gene id: 349521:HCH_RS17910
uniprot id: Q2SF45
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS10385
gene id: 349521:HCH_RS10385
uniprot id: Q2SJS3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

349521:HCH RS04710
gene id: 349521:HCH_RS04710
uniprot id: Q2SN48
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

349521:HCH RS04330
gene id: 349521:HCH_RS04330
uniprot id: Q2SND0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

349521:HCH RS09095
gene id: 349521:HCH_RS09095
uniprot id: Q2SKI4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

349521:HCH RS04350
gene id: 349521:HCH_RS04350
uniprot id: Q2SNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS23580
gene id: 349521:HCH_RS23580
uniprot id: Q2SBP9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

349521:HCH RS05900
gene id: 349521:HCH_RS05900
uniprot id: Q2SME4
names: Similarity
messages: Belongs to the thioredoxin family.

349521:HCH RS24185
gene id: 349521:HCH_RS24185
uniprot id: Q2SBC0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

349521:HCH RS07980
gene id: 349521:HCH_RS07980
uniprot id: Q2SL67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

349521:HCH RS22465
gene id: 349521:HCH_RS22465
uniprot id: Q2SCD6
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

349521:HCH RS26380
gene id: 349521:HCH_RS26380
uniprot id: Q2S9Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

349521:HCH RS16325
gene id: 349521:HCH_RS16325
uniprot id: Q2SG42
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS24300
gene id: 349521:HCH_RS24300
uniprot id: Q2SB96
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

349521:HCH RS00460
gene id: 349521:HCH_RS00460
uniprot id: Q2SQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

349521:HCH RS06255
gene id: 349521:HCH_RS06255
uniprot id: Q2SM69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

349521:HCH RS11090
gene id: 349521:HCH_RS11090
uniprot id: Q2SJC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

349521:HCH RS21935
gene id: 349521:HCH_RS21935
uniprot id: Q2SCP1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

349521:HCH RS19525
gene id: 349521:HCH_RS19525
uniprot id: Q2SE49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

349521:HCH RS00295
gene id: 349521:HCH_RS00295
uniprot id: Q2SQT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

349521:HCH RS12205
gene id: 349521:HCH_RS12205
uniprot id: Q2SIN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

349521:HCH RS20505
gene id: 349521:HCH_RS20505
uniprot id: Q2SDJ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS28290
gene id: 349521:HCH_RS28290
uniprot id: Q2S8V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

349521:HCH RS12225
gene id: 349521:HCH_RS12225
uniprot id: Q2SIN3
names: Similarity
messages: Belongs to the UPF0434 family.

349521:HCH RS29790
gene id: 349521:HCH_RS29790
uniprot id: Q2S7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS27990
gene id: 349521:HCH_RS27990
uniprot id: Q2S906
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

349521:HCH RS29615
gene id: 349521:HCH_RS29615
uniprot id: Q2S821
names: Cofactor
messages: Binds 1 phosphopantetheine covalently.

349521:HCH RS28270
gene id: 349521:HCH_RS28270
uniprot id: Q2S8V7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

349521:HCH RS06055
gene id: 349521:HCH_RS06055
uniprot id: Q2SMB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

349521:HCH RS27505
gene id: 349521:HCH_RS27505
uniprot id: Q2S9B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

349521:HCH RS09580
gene id: 349521:HCH_RS09580
uniprot id: Q2SK84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

349521:HCH RS09745
gene id: 349521:HCH_RS09745
uniprot id: Q2SK50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

349521:HCH RS00235
gene id: 349521:HCH_RS00235
uniprot id: Q2SQV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

349521:HCH RS01015
gene id: 349521:HCH_RS01015
uniprot id: Q2SQD5
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

349521:HCH RS00160
gene id: 349521:HCH_RS00160
uniprot id: Q2SQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

349521:HCH RS32275
gene id: 349521:HCH_RS32275
uniprot id: Q2SJ74
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS20650
gene id: 349521:HCH_RS20650
uniprot id: Q2SDG7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

349521:HCH RS29805
gene id: 349521:HCH_RS29805
uniprot id: Q2S7Y1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

349521:HCH RS29380
gene id: 349521:HCH_RS29380
uniprot id: Q2S871
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

349521:HCH RS03265
gene id: 349521:HCH_RS03265
uniprot id: Q2SP02
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

349521:HCH RS28235
gene id: 349521:HCH_RS28235
uniprot id: Q2S8W4
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

349521:HCH RS21290
gene id: 349521:HCH_RS21290
uniprot id: Q2SD31
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

349521:HCH RS21025
gene id: 349521:HCH_RS21025
uniprot id: Q2SD90
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS24665
gene id: 349521:HCH_RS24665
uniprot id: Q2SB19
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

349521:HCH RS06040
gene id: 349521:HCH_RS06040
uniprot id: Q2SMB8
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

349521:HCH RS28900
gene id: 349521:HCH_RS28900
uniprot id: Q2S8H8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS20030
gene id: 349521:HCH_RS20030
uniprot id: Q2SDU1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

349521:HCH RS27920
gene id: 349521:HCH_RS27920
uniprot id: Q2S920
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

349521:HCH RS10455
gene id: 349521:HCH_RS10455
uniprot id: Q2SJQ5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

349521:HCH RS08520
gene id: 349521:HCH_RS08520
uniprot id: Q2SKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoS subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.

349521:HCH RS22840
gene id: 349521:HCH_RS22840
uniprot id: Q2SC59
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS11835
gene id: 349521:HCH_RS11835
uniprot id: Q2SIX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

349521:HCH RS18365
gene id: 349521:HCH_RS18365
uniprot id: Q2SEU7
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

349521:HCH RS08880
gene id: 349521:HCH_RS08880
uniprot id: Q2SKN3
names: Subunit
messages: Homodimer.

349521:HCH RS02995
gene id: 349521:HCH_RS02995
uniprot id: Q2SP65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

349521:HCH RS10630
gene id: 349521:HCH_RS10630
uniprot id: Q2SJL6
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

349521:HCH RS10125
gene id: 349521:HCH_RS10125
uniprot id: Q2SJX7
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS14035
gene id: 349521:HCH_RS14035
uniprot id: Q2SHJ2
names: Similarity
messages: Belongs to the UPF0175 family.

349521:HCH RS26440
gene id: 349521:HCH_RS26440
uniprot id: Q2S9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

349521:HCH RS25860
gene id: 349521:HCH_RS25860
uniprot id: Q2SAA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS24530
gene id: 349521:HCH_RS24530
uniprot id: Q2SB47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (HmuV), two transmembrane proteins (HmuU) and a solute-binding protein (HmuT).

349521:HCH RS12270
gene id: 349521:HCH_RS12270
uniprot id: Q2SIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

349521:HCH RS01145
gene id: 349521:HCH_RS01145
uniprot id: Q2SQA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

349521:HCH RS05090
gene id: 349521:HCH_RS05090
uniprot id: Q2SMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS06285
gene id: 349521:HCH_RS06285
uniprot id: Q2SM63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS01280
gene id: 349521:HCH_RS01280
uniprot id: Q2SQ79
names: Similarity
messages: Belongs to the leucine-binding protein family.

349521:HCH RS17575
gene id: 349521:HCH_RS17575
uniprot id: Q2SFC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

349521:HCH RS26430
gene id: 349521:HCH_RS26430
uniprot id: Q2S9Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

349521:HCH RS14995
gene id: 349521:HCH_RS14995
uniprot id: Q2SGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

349521:HCH RS28460
gene id: 349521:HCH_RS28460
uniprot id: Q2S8R7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS04825
gene id: 349521:HCH_RS04825
uniprot id: Q2SN23
names: Similarity
messages: Belongs to the peptidase M24B family.

349521:HCH RS09765
gene id: 349521:HCH_RS09765
uniprot id: Q2SK46
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

349521:HCH RS26065
gene id: 349521:HCH_RS26065
uniprot id: Q2SA61
names: Similarity
messages: Belongs to the PhzF family.

349521:HCH RS00050
gene id: 349521:HCH_RS00050
uniprot id: Q2SQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS14915
gene id: 349521:HCH_RS14915
uniprot id: Q2SGZ9
names: Similarity
messages: Belongs to the Gfa family.

349521:HCH RS26640
gene id: 349521:HCH_RS26640
uniprot id: Q2S9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS16660
gene id: 349521:HCH_RS16660
uniprot id: Q2SFX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

349521:HCH RS21280
gene id: 349521:HCH_RS21280
uniprot id: Q2SD33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

349521:HCH RS26510
gene id: 349521:HCH_RS26510
uniprot id: Q2S9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

349521:HCH RS05815
gene id: 349521:HCH_RS05815
uniprot id: Q2SMG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS08430
gene id: 349521:HCH_RS08430
uniprot id: Q2SKX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

349521:HCH RS00225
gene id: 349521:HCH_RS00225
uniprot id: Q2SQV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

349521:HCH RS00765
gene id: 349521:HCH_RS00765
uniprot id: Q2SQI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

349521:HCH RS16970
gene id: 349521:HCH_RS16970
uniprot id: Q2SFQ1
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS03370
gene id: 349521:HCH_RS03370
uniprot id: Q2SNX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS31890
gene id: 349521:HCH_RS31890
uniprot id: Q2S6P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

349521:HCH RS27095
gene id: 349521:HCH_RS27095
uniprot id: Q2S9K3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS23525
gene id: 349521:HCH_RS23525
uniprot id: Q2SBR1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

349521:HCH RS00010
gene id: 349521:HCH_RS00010
uniprot id: Q2SQZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

349521:HCH RS23980
gene id: 349521:HCH_RS23980
uniprot id: Q2SBG4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

349521:HCH RS05785
gene id: 349521:HCH_RS05785
uniprot id: Q2SMG9
names: Similarity
messages: Belongs to the PhzF family.

349521:HCH RS05160
gene id: 349521:HCH_RS05160
uniprot id: Q2SMV2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS31335
gene id: 349521:HCH_RS31335
uniprot id: Q2S715
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS20205
gene id: 349521:HCH_RS20205
uniprot id: Q2SDQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

349521:HCH RS31395
gene id: 349521:HCH_RS31395
uniprot id: Q2S700
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

349521:HCH RS20260
gene id: 349521:HCH_RS20260
uniprot id: Q2SDN9
names: Similarity
messages: Belongs to the acylphosphatase family.

349521:HCH RS08125
gene id: 349521:HCH_RS08125
uniprot id: Q2SL38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

349521:HCH RS26300
gene id: 349521:HCH_RS26300
uniprot id: Q2SA12
names: Similarity
messages: Belongs to the MotB family.

349521:HCH RS12160
gene id: 349521:HCH_RS12160
uniprot id: Q2SIP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

349521:HCH RS28645
gene id: 349521:HCH_RS28645
uniprot id: Q2S8M7
names: Similarity
messages: Belongs to the GSP E family.

349521:HCH RS04985
gene id: 349521:HCH_RS04985
uniprot id: Q2SMZ0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

349521:HCH RS21165
gene id: 349521:HCH_RS21165
uniprot id: Q2SD55
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

349521:HCH RS05855
gene id: 349521:HCH_RS05855
uniprot id: Q2SMF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

349521:HCH RS20000
gene id: 349521:HCH_RS20000
uniprot id: Q2SDU7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

349521:HCH RS24170
gene id: 349521:HCH_RS24170
uniprot id: Q2SBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

349521:HCH RS06360
gene id: 349521:HCH_RS06360
uniprot id: Q2SM48
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

349521:HCH RS11120
gene id: 349521:HCH_RS11120
uniprot id: Q2SJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (ModC), two transmembrane proteins (ModB) and a solute-binding protein (ModA).

349521:HCH RS23555
gene id: 349521:HCH_RS23555
uniprot id: Q2SBQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

349521:HCH RS06140
gene id: 349521:HCH_RS06140
uniprot id: Q2SM95
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349521:HCH RS11010
gene id: 349521:HCH_RS11010
uniprot id: Q2SJD8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

349521:HCH RS16980
gene id: 349521:HCH_RS16980
uniprot id: Q2SFP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS06900
gene id: 349521:HCH_RS06900
uniprot id: Q2SLT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

349521:HCH RS00605
gene id: 349521:HCH_RS00605
uniprot id: Q2SQM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS31470
gene id: 349521:HCH_RS31470
uniprot id: Q2S6Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

349521:HCH RS01320
gene id: 349521:HCH_RS01320
uniprot id: Q2SQ71
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

349521:HCH RS22225
gene id: 349521:HCH_RS22225
uniprot id: Q2SCI4
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS06825
gene id: 349521:HCH_RS06825
uniprot id: Q2SLV5
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

349521:HCH RS19300
gene id: 349521:HCH_RS19300
uniprot id: Q2SE97
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS20570
gene id: 349521:HCH_RS20570
uniprot id: Q2SDH9
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

349521:HCH RS15530
gene id: 349521:HCH_RS15530
uniprot id: Q2SGM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS22385
gene id: 349521:HCH_RS22385
uniprot id: Q2SCF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS20970
gene id: 349521:HCH_RS20970
uniprot id: Q2SDA1
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

349521:HCH RS20860
gene id: 349521:HCH_RS20860
uniprot id: Q2SDC6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

349521:HCH RS28640
gene id: 349521:HCH_RS28640
uniprot id: Q2S8M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

349521:HCH RS12995
gene id: 349521:HCH_RS12995
uniprot id: Q2SI66
names: Similarity
messages: Belongs to the phage antitermination Q type 1 family.

349521:HCH RS04615
gene id: 349521:HCH_RS04615
uniprot id: Q2SN68
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS02555
gene id: 349521:HCH_RS02555
uniprot id: Q2SPG0
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

349521:HCH RS23820
gene id: 349521:HCH_RS23820
uniprot id: Q2SBJ7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

349521:HCH RS19935
gene id: 349521:HCH_RS19935
uniprot id: Q2SDV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

349521:HCH RS00290
gene id: 349521:HCH_RS00290
uniprot id: Q2SQU0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

349521:HCH RS04020
gene id: 349521:HCH_RS04020
uniprot id: Q2SNJ6
names: Similarity
messages: Belongs to the YjiK family.

349521:HCH RS22310
gene id: 349521:HCH_RS22310
uniprot id: Q2SCG7
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS00130
gene id: 349521:HCH_RS00130
uniprot id: Q2SQX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

349521:HCH RS08810
gene id: 349521:HCH_RS08810
uniprot id: Q2SKP7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS16455
gene id: 349521:HCH_RS16455
uniprot id: Q2SG16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

349521:HCH RS23995
gene id: 349521:HCH_RS23995
uniprot id: Q2SBG0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

349521:HCH RS23180
gene id: 349521:HCH_RS23180
uniprot id: Q2SBY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

349521:HCH RS23975
gene id: 349521:HCH_RS23975
uniprot id: Q2SBG5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

349521:HCH RS23380
gene id: 349521:HCH_RS23380
uniprot id: Q2SBT9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

349521:HCH RS03435
gene id: 349521:HCH_RS03435
uniprot id: Q2SNW7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

349521:HCH RS10120
gene id: 349521:HCH_RS10120
uniprot id: Q2SJX8
names: Subcellular Location Annotation
messages: Cell outer membrane

349521:HCH RS06065
gene id: 349521:HCH_RS06065
uniprot id: Q2SMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

349521:HCH RS21845
gene id: 349521:HCH_RS21845
uniprot id: Q2SCR4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase Z family.
messages: Binds 2 Zn(2+) ions.
messages: Homodimer.
messages: Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

349521:HCH RS20490
gene id: 349521:HCH_RS20490
uniprot id: Q2SDJ5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

349521:HCH RS10945
gene id: 349521:HCH_RS10945
uniprot id: Q2SJF2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

349521:HCH RS07930
gene id: 349521:HCH_RS07930
uniprot id: Q2SL78
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS21560
gene id: 349521:HCH_RS21560
uniprot id: Q2SCX3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

349521:HCH RS01585
gene id: 349521:HCH_RS01585
uniprot id: Q2SQ14
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

349521:HCH RS01875
gene id: 349521:HCH_RS01875
uniprot id: Q2SPV0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

349521:HCH RS24000
gene id: 349521:HCH_RS24000
uniprot id: Q2SBF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

349521:HCH RS10635
gene id: 349521:HCH_RS10635
uniprot id: Q2SJL5
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

349521:HCH RS00395
gene id: 349521:HCH_RS00395
uniprot id: Q2SQR9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349521:HCH RS14810
gene id: 349521:HCH_RS14810
uniprot id: Q2SH21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS04580
gene id: 349521:HCH_RS04580
uniprot id: Q2SN75
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

349521:HCH RS29385
gene id: 349521:HCH_RS29385
uniprot id: Q2S870
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS00410
gene id: 349521:HCH_RS00410
uniprot id: Q2SQR6
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

349521:HCH RS31025
gene id: 349521:HCH_RS31025
uniprot id: Q2S782
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

349521:HCH RS31925
gene id: 349521:HCH_RS31925
uniprot id: Q2S6N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

349521:HCH RS04980
gene id: 349521:HCH_RS04980
uniprot id: Q2SMZ1
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS08995
gene id: 349521:HCH_RS08995
uniprot id: Q2SKK6
names: Similarity
messages: Belongs to the UPF0145 family.

349521:HCH RS29935
gene id: 349521:HCH_RS29935
uniprot id: Q2S7V4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS09640
gene id: 349521:HCH_RS09640
uniprot id: Q2SK73
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.

349521:HCH RS17310
gene id: 349521:HCH_RS17310
uniprot id: Q2SFI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

349521:HCH RS29695
gene id: 349521:HCH_RS29695
uniprot id: Q2S804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

349521:HCH RS10985
gene id: 349521:HCH_RS10985
uniprot id: Q2SJE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

349521:HCH RS26000
gene id: 349521:HCH_RS26000
uniprot id: Q2SA75
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

349521:HCH RS29765
gene id: 349521:HCH_RS29765
uniprot id: Q2S7Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

349521:HCH RS21905
gene id: 349521:HCH_RS21905
uniprot id: Q2SCP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS14970
gene id: 349521:HCH_RS14970
uniprot id: Q2SGY7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

349521:HCH RS24175
gene id: 349521:HCH_RS24175
uniprot id: Q2SBC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

349521:HCH RS15755
gene id: 349521:HCH_RS15755
uniprot id: Q2SGH4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

349521:HCH RS32675
gene id: 349521:HCH_RS32675
uniprot id: Q2SC46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctE/SipB/YopB family.
messages: Host membrane

349521:HCH RS00755
gene id: 349521:HCH_RS00755
uniprot id: Q2SQJ1
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS10575
gene id: 349521:HCH_RS10575
uniprot id: Q2SJM7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS24225
gene id: 349521:HCH_RS24225
uniprot id: Q2SBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

349521:HCH RS00220
gene id: 349521:HCH_RS00220
uniprot id: Q2SQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

349521:HCH RS01070
gene id: 349521:HCH_RS01070
uniprot id: Q2SQC4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349521:HCH RS04840
gene id: 349521:HCH_RS04840
uniprot id: Q2SN20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

349521:HCH RS26150
gene id: 349521:HCH_RS26150
uniprot id: Q2SA42
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

349521:HCH RS27375
gene id: 349521:HCH_RS27375
uniprot id: Q2S9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

349521:HCH RS20045
gene id: 349521:HCH_RS20045
uniprot id: Q2SDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

349521:HCH RS04415
gene id: 349521:HCH_RS04415
uniprot id: Q2SNB3
names: Similarity
messages: Belongs to the AlaDH/PNT family.

349521:HCH RS11025
gene id: 349521:HCH_RS11025
uniprot id: Q2SJD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS17850
gene id: 349521:HCH_RS17850
uniprot id: Q2SF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

349521:HCH RS02635
gene id: 349521:HCH_RS02635
uniprot id: Q2SPE4
names: Similarity
messages: Belongs to the hyi family.

349521:HCH RS07720
gene id: 349521:HCH_RS07720
uniprot id: Q2SLB8
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS12240
gene id: 349521:HCH_RS12240
uniprot id: Q2SIN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

349521:HCH RS32200
gene id: 349521:HCH_RS32200
uniprot id: Q2SKR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Syd family.
messages: Cell inner membrane
messages: Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.

349521:HCH RS08305
gene id: 349521:HCH_RS08305
uniprot id: Q2SL02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349521:HCH RS09845
gene id: 349521:HCH_RS09845
uniprot id: Q2SK32
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

349521:HCH RS19925
gene id: 349521:HCH_RS19925
uniprot id: Q2SDW1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

349521:HCH RS28455
gene id: 349521:HCH_RS28455
uniprot id: Q2S8R8
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

349521:HCH RS18220
gene id: 349521:HCH_RS18220
uniprot id: Q2SEY1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

349521:HCH RS30425
gene id: 349521:HCH_RS30425
uniprot id: Q2S7K5
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS13845
gene id: 349521:HCH_RS13845
uniprot id: Q2SHN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

349521:HCH RS15550
gene id: 349521:HCH_RS15550
uniprot id: Q2SGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

349521:HCH RS26680
gene id: 349521:HCH_RS26680
uniprot id: Q2S9U1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

349521:HCH RS29965
gene id: 349521:HCH_RS29965
uniprot id: Q2S7U8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS21005
gene id: 349521:HCH_RS21005
uniprot id: Q2SD93
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

349521:HCH RS22615
gene id: 349521:HCH_RS22615
uniprot id: Q2SCA7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

349521:HCH RS07620
gene id: 349521:HCH_RS07620
uniprot id: Q2SLD7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS23950
gene id: 349521:HCH_RS23950
uniprot id: Q2SBH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

349521:HCH RS26605
gene id: 349521:HCH_RS26605
uniprot id: Q2S9V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

349521:HCH RS21410
gene id: 349521:HCH_RS21410
uniprot id: Q2SD07
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

349521:HCH RS10930
gene id: 349521:HCH_RS10930
uniprot id: Q2SJF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

349521:HCH RS18310
gene id: 349521:HCH_RS18310
uniprot id: Q2SEW2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

349521:HCH RS31955
gene id: 349521:HCH_RS31955
uniprot id: Q2S6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

349521:HCH RS23470
gene id: 349521:HCH_RS23470
uniprot id: Q2SBS1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

349521:HCH RS16805
gene id: 349521:HCH_RS16805
uniprot id: Q2SFT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

349521:HCH RS28980
gene id: 349521:HCH_RS28980
uniprot id: Q2S8G2
names: Similarity
messages: Belongs to the Rsd/AlgQ family.

349521:HCH RS09675
gene id: 349521:HCH_RS09675
uniprot id: Q2SK66
names: Similarity
messages: Belongs to the YciI family.

349521:HCH RS29650
gene id: 349521:HCH_RS29650
uniprot id: Q2S814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

349521:HCH RS26355
gene id: 349521:HCH_RS26355
uniprot id: Q2SA01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

349521:HCH RS13205
gene id: 349521:HCH_RS13205
uniprot id: Q2SI24
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS12080
gene id: 349521:HCH_RS12080
uniprot id: Q2SIR4
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS19910
gene id: 349521:HCH_RS19910
uniprot id: Q2SDW4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

349521:HCH RS27025
gene id: 349521:HCH_RS27025
uniprot id: Q2S9L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

349521:HCH RS04460
gene id: 349521:HCH_RS04460
uniprot id: Q2SNA1
names: Similarity
messages: Belongs to the PspA/IM30 family.

349521:HCH RS30675
gene id: 349521:HCH_RS30675
uniprot id: Q2S7F6
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

349521:HCH RS01350
gene id: 349521:HCH_RS01350
uniprot id: Q2SQ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

349521:HCH RS04855
gene id: 349521:HCH_RS04855
uniprot id: Q2SN17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

349521:HCH RS12705
gene id: 349521:HCH_RS12705
uniprot id: Q2SID2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

349521:HCH RS07550
gene id: 349521:HCH_RS07550
uniprot id: Q2SLF3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349521:HCH RS00165
gene id: 349521:HCH_RS00165
uniprot id: Q2SQW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

349521:HCH RS16960
gene id: 349521:HCH_RS16960
uniprot id: Q2SFQ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349521:HCH RS05760
gene id: 349521:HCH_RS05760
uniprot id: Q2SMH3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS17660
gene id: 349521:HCH_RS17660
uniprot id: Q2SFA5
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

349521:HCH RS21975
gene id: 349521:HCH_RS21975
uniprot id: Q2SCN3
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

349521:HCH RS03965
gene id: 349521:HCH_RS03965
uniprot id: Q2SNK9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

349521:HCH RS17630
gene id: 349521:HCH_RS17630
uniprot id: Q2SFB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS16670
gene id: 349521:HCH_RS16670
uniprot id: Q2SFW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC41A transporter family.
messages: Membrane

349521:HCH RS17505
gene id: 349521:HCH_RS17505
uniprot id: Q2SFE0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS09830
gene id: 349521:HCH_RS09830
uniprot id: Q2SK36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

349521:HCH RS23715
gene id: 349521:HCH_RS23715
uniprot id: Q2SBM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

349521:HCH RS21565
gene id: 349521:HCH_RS21565
uniprot id: Q2SCX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

349521:HCH RS09225
gene id: 349521:HCH_RS09225
uniprot id: Q2SKF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

349521:HCH RS10650
gene id: 349521:HCH_RS10650
uniprot id: Q2SJL2
names: Similarity
messages: Belongs to the ClpA/ClpB family.

349521:HCH RS23575
gene id: 349521:HCH_RS23575
uniprot id: Q2SBQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

349521:HCH RS12215
gene id: 349521:HCH_RS12215
uniprot id: Q2SIN5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

349521:HCH RS03895
gene id: 349521:HCH_RS03895
uniprot id: Q2SNM4
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

349521:HCH RS11505
gene id: 349521:HCH_RS11505
uniprot id: Q2SJ31
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

349521:HCH RS08635
gene id: 349521:HCH_RS08635
uniprot id: Q2SKT4
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

349521:HCH RS12835
gene id: 349521:HCH_RS12835
uniprot id: Q2SIA1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS29960
gene id: 349521:HCH_RS29960
uniprot id: Q2S7U9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

349521:HCH RS17145
gene id: 349521:HCH_RS17145
uniprot id: Q2SFL4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349521:HCH RS08680
gene id: 349521:HCH_RS08680
uniprot id: Q2SKS5
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

349521:HCH RS23000
gene id: 349521:HCH_RS23000
uniprot id: Q2SC24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SctL stator family.
messages: Cytoplasm

349521:HCH RS15895
gene id: 349521:HCH_RS15895
uniprot id: Q2SGE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

349521:HCH RS00725
gene id: 349521:HCH_RS00725
uniprot id: Q2SQJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

349521:HCH RS22865
gene id: 349521:HCH_RS22865
uniprot id: Q2SC53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

349521:HCH RS20560
gene id: 349521:HCH_RS20560
uniprot id: Q2SDI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

349521:HCH RS11270
gene id: 349521:HCH_RS11270
uniprot id: Q2SJ82
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349521:HCH RS26915
gene id: 349521:HCH_RS26915
uniprot id: Q2S9P1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS23495
gene id: 349521:HCH_RS23495
uniprot id: Q2SBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

349521:HCH RS27850
gene id: 349521:HCH_RS27850
uniprot id: Q2S935
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

349521:HCH RS28590
gene id: 349521:HCH_RS28590
uniprot id: Q2S8N9
names: Cofactor
messages: Probably binds two magnesium or manganese ions per subunit.

349521:HCH RS15115
gene id: 349521:HCH_RS15115
uniprot id: Q2SGV5
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

349521:HCH RS29015
gene id: 349521:HCH_RS29015
uniprot id: Q2S8F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

349521:HCH RS27900
gene id: 349521:HCH_RS27900
uniprot id: Q2S924
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

349521:HCH RS04070
gene id: 349521:HCH_RS04070
uniprot id: Q2SNI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

349521:HCH RS29560
gene id: 349521:HCH_RS29560
uniprot id: Q2S833
names: Similarity
messages: Belongs to the histone deacetylase family.

349521:HCH RS05515
gene id: 349521:HCH_RS05515
uniprot id: Q2SMM4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349521:HCH RS26220
gene id: 349521:HCH_RS26220
uniprot id: Q2SA28
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

349521:HCH RS01570
gene id: 349521:HCH_RS01570
uniprot id: Q2SQ17
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the porin LamB (TC 1.B.3) family.
messages: By maltose.
messages: Cell outer membrane
messages: Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.
messages: Involved in the transport of maltose and maltodextrins.

349521:HCH RS26210
gene id: 349521:HCH_RS26210
uniprot id: Q2SA30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

349521:HCH RS26270
gene id: 349521:HCH_RS26270
uniprot id: Q2SA18
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

349521:HCH RS05550
gene id: 349521:HCH_RS05550
uniprot id: Q2SML7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

349521:HCH RS21545
gene id: 349521:HCH_RS21545
uniprot id: Q2SCX6
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

349521:HCH RS16345
gene id: 349521:HCH_RS16345
uniprot id: Q2SG38
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS25785
gene id: 349521:HCH_RS25785
uniprot id: Q2SAC3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349521:HCH RS00550
gene id: 349521:HCH_RS00550
uniprot id: Q2SQN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

349521:HCH RS09730
gene id: 349521:HCH_RS09730
uniprot id: Q2SK53
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

349521:HCH RS03780
gene id: 349521:HCH_RS03780
uniprot id: Q2SNP7
names: Subcellular Location Annotation
messages: Membrane

349521:HCH RS07040
gene id: 349521:HCH_RS07040
uniprot id: Q2SLR0
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

349521:HCH RS24020
gene id: 349521:HCH_RS24020
uniprot id: Q2SBF4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.