349161:DRED RS10640
gene id: 349161:DRED_RS10640
uniprot id: A4J610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

349161:DRED RS10245
gene id: 349161:DRED_RS10245
uniprot id: A4J5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

349161:DRED RS12805
gene id: 349161:DRED_RS12805
uniprot id: A4J765
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

349161:DRED RS00730
gene id: 349161:DRED_RS00730
uniprot id: A4J0T3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

349161:DRED RS13355
gene id: 349161:DRED_RS13355
uniprot id: A4J7G7
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS00270
gene id: 349161:DRED_RS00270
uniprot id: A4J0J1
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

349161:DRED RS09085
gene id: 349161:DRED_RS09085
uniprot id: A4J568
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS12990
gene id: 349161:DRED_RS12990
uniprot id: A4J799
names: Similarity
messages: Belongs to the MotB family.

349161:DRED RS12785
gene id: 349161:DRED_RS12785
uniprot id: A4J761
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

349161:DRED RS16990
gene id: 349161:DRED_RS16990
uniprot id: A4J9E4
names: Similarity
messages: Belongs to the SleB family.

349161:DRED RS14430
gene id: 349161:DRED_RS14430
uniprot id: A4J805
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

349161:DRED RS08800
gene id: 349161:DRED_RS08800
uniprot id: A4J514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS05755
gene id: 349161:DRED_RS05755
uniprot id: A4J3E7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

349161:DRED RS15975
gene id: 349161:DRED_RS15975
uniprot id: A4J8U7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

349161:DRED RS14715
gene id: 349161:DRED_RS14715
uniprot id: A4J861
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349161:DRED RS01880
gene id: 349161:DRED_RS01880
uniprot id: A4J1E9
names: Similarity
messages: Belongs to the MotB family.

349161:DRED RS16310
gene id: 349161:DRED_RS16310
uniprot id: A4J912
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS08610
gene id: 349161:DRED_RS08610
uniprot id: A4J4X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS01025
gene id: 349161:DRED_RS01025
uniprot id: A4J0Y5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349161:DRED RS00365
gene id: 349161:DRED_RS00365
uniprot id: A4J0L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

349161:DRED RS11140
gene id: 349161:DRED_RS11140
uniprot id: A4J6A8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

349161:DRED RS03615
gene id: 349161:DRED_RS03615
uniprot id: A4J2A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane

349161:DRED RS05520
gene id: 349161:DRED_RS05520
uniprot id: A4J3A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

349161:DRED RS12450
gene id: 349161:DRED_RS12450
uniprot id: A4J6Z4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

349161:DRED RS02220
gene id: 349161:DRED_RS02220
uniprot id: A4J1K9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

349161:DRED RS08705
gene id: 349161:DRED_RS08705
uniprot id: A4J4Z5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349161:DRED RS13540
gene id: 349161:DRED_RS13540
uniprot id: A4J7K2
names: Similarity
messages: Belongs to the transpeptidase family.

349161:DRED RS11925
gene id: 349161:DRED_RS11925
uniprot id: A4J6P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS06940
gene id: 349161:DRED_RS06940
uniprot id: A4J412
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS08910
gene id: 349161:DRED_RS08910
uniprot id: A4J535
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

349161:DRED RS08580
gene id: 349161:DRED_RS08580
uniprot id: A4J4X1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

349161:DRED RS08415
gene id: 349161:DRED_RS08415
uniprot id: A4J4T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS10895
gene id: 349161:DRED_RS10895
uniprot id: A4J659
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS06110
gene id: 349161:DRED_RS06110
uniprot id: A4J3L4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

349161:DRED RS13485
gene id: 349161:DRED_RS13485
uniprot id: A4J7J1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

349161:DRED RS10620
gene id: 349161:DRED_RS10620
uniprot id: A4J606
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

349161:DRED RS02290
gene id: 349161:DRED_RS02290
uniprot id: A4J1M3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

349161:DRED RS07080
gene id: 349161:DRED_RS07080
uniprot id: A4J438
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS15305
gene id: 349161:DRED_RS15305
uniprot id: A4J8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

349161:DRED RS13155
gene id: 349161:DRED_RS13155
uniprot id: A4J7C7
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

349161:DRED RS04140
gene id: 349161:DRED_RS04140
uniprot id: A4J2L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

349161:DRED RS11740
gene id: 349161:DRED_RS11740
uniprot id: A4J6K9
names: Similarity
messages: Belongs to the UbiD family.

349161:DRED RS16695
gene id: 349161:DRED_RS16695
uniprot id: A4J987
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS02245
gene id: 349161:DRED_RS02245
uniprot id: A4J1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

349161:DRED RS01530
gene id: 349161:DRED_RS01530
uniprot id: A4J181
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS15290
gene id: 349161:DRED_RS15290
uniprot id: A4J8H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS15590
gene id: 349161:DRED_RS15590
uniprot id: A4J8M6
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS14485
gene id: 349161:DRED_RS14485
uniprot id: A4J816
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

349161:DRED RS03030
gene id: 349161:DRED_RS03030
uniprot id: A4J201
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

349161:DRED RS10260
gene id: 349161:DRED_RS10260
uniprot id: A4J5U1
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

349161:DRED RS03510
gene id: 349161:DRED_RS03510
uniprot id: A4J287
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS03445
gene id: 349161:DRED_RS03445
uniprot id: A4J275
names: Similarity
messages: Belongs to the HdrA family.

349161:DRED RS01370
gene id: 349161:DRED_RS01370
uniprot id: A4J149
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

349161:DRED RS02250
gene id: 349161:DRED_RS02250
uniprot id: A4J1L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

349161:DRED RS05790
gene id: 349161:DRED_RS05790
uniprot id: A4J3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

349161:DRED RS09715
gene id: 349161:DRED_RS09715
uniprot id: A4J5I7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

349161:DRED RS05680
gene id: 349161:DRED_RS05680
uniprot id: A4J3D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

349161:DRED RS09590
gene id: 349161:DRED_RS09590
uniprot id: A4J5G4
names: Similarity
messages: Belongs to the Tlp family.

349161:DRED RS14760
gene id: 349161:DRED_RS14760
uniprot id: A4J870
names: Similarity
messages: Belongs to the BMP lipoprotein family.

349161:DRED RS01255
gene id: 349161:DRED_RS01255
uniprot id: A4J126
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

349161:DRED RS11525
gene id: 349161:DRED_RS11525
uniprot id: A4J6H2
names: Similarity
messages: Belongs to the Ahb/Nir family.

349161:DRED RS03575
gene id: 349161:DRED_RS03575
uniprot id: A4J2A0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS14260
gene id: 349161:DRED_RS14260
uniprot id: A4J7X5
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS12125
gene id: 349161:DRED_RS12125
uniprot id: A4J6T1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS12870
gene id: 349161:DRED_RS12870
uniprot id: A4J778
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Has an FMN-binding N-terminal domain (NTD), an FAD-binding C-terminal domain (CTD), and a 4Fe-4S cluster between the two domains. CTD is the main contributor to the iron-reduction activity, and NTD and the 4Fe-4S cluster are not directly involved in such activity.
messages: Homotetramer.
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
messages: Metal reductase able to reduce Fe(III)-chelates to Fe(II)-chelates, as well as soluble Cr(VI) and U(VI), using NADH as electron donor. Cannot use NADPH as an electron donor. Is unable to reduce riboflavin and FMN with NADH as electron donor. May have an in vivo role in metal reduction in D.reducens, which is an organism capable of reducing contaminant heavy metals and radionuclides.

349161:DRED RS11110
gene id: 349161:DRED_RS11110
uniprot id: A4J6A2
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

349161:DRED RS00430
gene id: 349161:DRED_RS00430
uniprot id: A4J0M3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

349161:DRED RS13625
gene id: 349161:DRED_RS13625
uniprot id: A4J7L8
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

349161:DRED RS10090
gene id: 349161:DRED_RS10090
uniprot id: A4J5Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS16690
gene id: 349161:DRED_RS16690
uniprot id: A4J986
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

349161:DRED RS13615
gene id: 349161:DRED_RS13615
uniprot id: A4J7L6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

349161:DRED RS07650
gene id: 349161:DRED_RS07650
uniprot id: A4J4E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

349161:DRED RS04665
gene id: 349161:DRED_RS04665
uniprot id: A4J2U9
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

349161:DRED RS03675
gene id: 349161:DRED_RS03675
uniprot id: A4J2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

349161:DRED RS15840
gene id: 349161:DRED_RS15840
uniprot id: A4J8S4
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS09045
gene id: 349161:DRED_RS09045
uniprot id: A4J560
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits (By similarity). However, the metal reductase complex seems to be composed of a heterooctamer of 4 PyrK and 4 PyrD subunits (PubMed:25389064).
messages: Together with PyrK, also forms a metal reductase complex able to reduce Fe(III)-chelates to Fe(II)-chelates, as well as soluble Cr(VI) and U(VI), using NADH as electron donor. To a lesser extent, can also use NADPH as an electron donor. Is unable to reduce riboflavin and FMN with NADH as electron donor. May have an in vivo role in metal reduction in D.reducens, which is an organism capable of reducing contaminant heavy metals and radionuclides.

349161:DRED RS06205
gene id: 349161:DRED_RS06205
uniprot id: A4J3N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

349161:DRED RS03825
gene id: 349161:DRED_RS03825
uniprot id: A4J2E8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

349161:DRED RS09285
gene id: 349161:DRED_RS09285
uniprot id: A4J5A6
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

349161:DRED RS17570
gene id: 349161:DRED_RS17570
uniprot id: A4J9Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

349161:DRED RS10145
gene id: 349161:DRED_RS10145
uniprot id: A4J5R9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

349161:DRED RS14415
gene id: 349161:DRED_RS14415
uniprot id: A4J802
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

349161:DRED RS05465
gene id: 349161:DRED_RS05465
uniprot id: A4J389
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

349161:DRED RS03665
gene id: 349161:DRED_RS03665
uniprot id: A4J2B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sbp family.
messages: Cell membrane

349161:DRED RS12720
gene id: 349161:DRED_RS12720
uniprot id: A4J748
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

349161:DRED RS07975
gene id: 349161:DRED_RS07975
uniprot id: A4J4K8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

349161:DRED RS13190
gene id: 349161:DRED_RS13190
uniprot id: A4J7D4
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS11210
gene id: 349161:DRED_RS11210
uniprot id: A4J6C1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

349161:DRED RS12615
gene id: 349161:DRED_RS12615
uniprot id: A4J727
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

349161:DRED RS03345
gene id: 349161:DRED_RS03345
uniprot id: A4J254
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

349161:DRED RS05330
gene id: 349161:DRED_RS05330
uniprot id: A4J362
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS07915
gene id: 349161:DRED_RS07915
uniprot id: A4J4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS01305
gene id: 349161:DRED_RS01305
uniprot id: A4J136
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

349161:DRED RS03360
gene id: 349161:DRED_RS03360
uniprot id: A4J258
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

349161:DRED RS01375
gene id: 349161:DRED_RS01375
uniprot id: A4J150
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

349161:DRED RS01205
gene id: 349161:DRED_RS01205
uniprot id: A4J116
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

349161:DRED RS17430
gene id: 349161:DRED_RS17430
uniprot id: A4J9M8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

349161:DRED RS10600
gene id: 349161:DRED_RS10600
uniprot id: A4J602
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

349161:DRED RS09655
gene id: 349161:DRED_RS09655
uniprot id: A4J5H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

349161:DRED RS10425
gene id: 349161:DRED_RS10425
uniprot id: A4J5W8
names: Similarity
messages: Belongs to the ribF family.

349161:DRED RS13680
gene id: 349161:DRED_RS13680
uniprot id: A4J7M4
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS05890
gene id: 349161:DRED_RS05890
uniprot id: A4J3H3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS14530
gene id: 349161:DRED_RS14530
uniprot id: A4J824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

349161:DRED RS11115
gene id: 349161:DRED_RS11115
uniprot id: A4J6A3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

349161:DRED RS02405
gene id: 349161:DRED_RS02405
uniprot id: A4J1P6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349161:DRED RS07545
gene id: 349161:DRED_RS07545
uniprot id: A4J4C2
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

349161:DRED RS01265
gene id: 349161:DRED_RS01265
uniprot id: A4J128
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

349161:DRED RS10860
gene id: 349161:DRED_RS10860
uniprot id: A4J652
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
messages: Membrane

349161:DRED RS15805
gene id: 349161:DRED_RS15805
uniprot id: A4J8R7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

349161:DRED RS16905
gene id: 349161:DRED_RS16905
uniprot id: A4J9C7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS14625
gene id: 349161:DRED_RS14625
uniprot id: A4J843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

349161:DRED RS11555
gene id: 349161:DRED_RS11555
uniprot id: A4J6H8
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

349161:DRED RS02070
gene id: 349161:DRED_RS02070
uniprot id: A4J1I1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

349161:DRED RS01335
gene id: 349161:DRED_RS01335
uniprot id: A4J142
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

349161:DRED RS10855
gene id: 349161:DRED_RS10855
uniprot id: A4J651
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

349161:DRED RS14250
gene id: 349161:DRED_RS14250
uniprot id: A4J7X3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

349161:DRED RS02370
gene id: 349161:DRED_RS02370
uniprot id: A4J1N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

349161:DRED RS01380
gene id: 349161:DRED_RS01380
uniprot id: A4J151
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

349161:DRED RS02380
gene id: 349161:DRED_RS02380
uniprot id: A4J1P1
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

349161:DRED RS12340
gene id: 349161:DRED_RS12340
uniprot id: A4J6X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

349161:DRED RS14815
gene id: 349161:DRED_RS14815
uniprot id: A4J881
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS13165
gene id: 349161:DRED_RS13165
uniprot id: A4J7C9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349161:DRED RS09220
gene id: 349161:DRED_RS09220
uniprot id: A4J595
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS11635
gene id: 349161:DRED_RS11635
uniprot id: A4J6J2
names: Subcellular Location Annotation
messages: Cytoplasm

349161:DRED RS09215
gene id: 349161:DRED_RS09215
uniprot id: A4J594
names: Similarity
messages: Belongs to the leucine-binding protein family.

349161:DRED RS12800
gene id: 349161:DRED_RS12800
uniprot id: A4J764
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

349161:DRED RS01125
gene id: 349161:DRED_RS01125
uniprot id: A4J100
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

349161:DRED RS10195
gene id: 349161:DRED_RS10195
uniprot id: A4J5S8
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

349161:DRED RS14355
gene id: 349161:DRED_RS14355
uniprot id: A4J7Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmE subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

349161:DRED RS02145
gene id: 349161:DRED_RS02145
uniprot id: A4J1J6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349161:DRED RS17475
gene id: 349161:DRED_RS17475
uniprot id: A4J9N8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

349161:DRED RS11135
gene id: 349161:DRED_RS11135
uniprot id: A4J6A7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

349161:DRED RS12470
gene id: 349161:DRED_RS12470
uniprot id: A4J6Z8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

349161:DRED RS11090
gene id: 349161:DRED_RS11090
uniprot id: A4J698
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

349161:DRED RS02215
gene id: 349161:DRED_RS02215
uniprot id: A4J1K8
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

349161:DRED RS06835
gene id: 349161:DRED_RS06835
uniprot id: A4J3Z2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

349161:DRED RS01785
gene id: 349161:DRED_RS01785
uniprot id: A4J1D1
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

349161:DRED RS14480
gene id: 349161:DRED_RS14480
uniprot id: A4J815
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

349161:DRED RS07135
gene id: 349161:DRED_RS07135
uniprot id: A4J447
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS00550
gene id: 349161:DRED_RS00550
uniprot id: A4J0P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

349161:DRED RS10065
gene id: 349161:DRED_RS10065
uniprot id: A4J5Q3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

349161:DRED RS15170
gene id: 349161:DRED_RS15170
uniprot id: A4J8E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

349161:DRED RS12580
gene id: 349161:DRED_RS12580
uniprot id: A4J720
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

349161:DRED RS07555
gene id: 349161:DRED_RS07555
uniprot id: A4J4C4
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

349161:DRED RS04205
gene id: 349161:DRED_RS04205
uniprot id: A4J2M3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS05775
gene id: 349161:DRED_RS05775
uniprot id: A4J3F1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

349161:DRED RS14675
gene id: 349161:DRED_RS14675
uniprot id: A4J853
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

349161:DRED RS12300
gene id: 349161:DRED_RS12300
uniprot id: A4J6W5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS04055
gene id: 349161:DRED_RS04055
uniprot id: A4J2J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS03835
gene id: 349161:DRED_RS03835
uniprot id: A4J2F0
names: Similarity
messages: Belongs to the YggT family.

349161:DRED RS07325
gene id: 349161:DRED_RS07325
uniprot id: A4J483
names: Similarity
messages: Belongs to the FBPase class 2 family.

349161:DRED RS03610
gene id: 349161:DRED_RS03610
uniprot id: A4J2A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

349161:DRED RS01155
gene id: 349161:DRED_RS01155
uniprot id: A4J106
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

349161:DRED RS14585
gene id: 349161:DRED_RS14585
uniprot id: A4J835
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

349161:DRED RS08140
gene id: 349161:DRED_RS08140
uniprot id: A4J4N7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS03655
gene id: 349161:DRED_RS03655
uniprot id: A4J2B6
names: Similarity
messages: Belongs to the UPF0749 family.

349161:DRED RS13560
gene id: 349161:DRED_RS13560
uniprot id: A4J7K6
names: Similarity
messages: Belongs to the UPF0758 family.

349161:DRED RS01385
gene id: 349161:DRED_RS01385
uniprot id: A4J152
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

349161:DRED RS13550
gene id: 349161:DRED_RS13550
uniprot id: A4J7K4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

349161:DRED RS11515
gene id: 349161:DRED_RS11515
uniprot id: A4J6H0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS15350
gene id: 349161:DRED_RS15350
uniprot id: A4J8I3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

349161:DRED RS01315
gene id: 349161:DRED_RS01315
uniprot id: A4J138
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

349161:DRED RS01760
gene id: 349161:DRED_RS01760
uniprot id: A4J1C6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

349161:DRED RS11810
gene id: 349161:DRED_RS11810
uniprot id: A4J6M2
names: Caution
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS09980
gene id: 349161:DRED_RS09980
uniprot id: A4J5N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

349161:DRED RS00850
gene id: 349161:DRED_RS00850
uniprot id: A4J0V7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

349161:DRED RS04660
gene id: 349161:DRED_RS04660
uniprot id: A4J2U8
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS04845
gene id: 349161:DRED_RS04845
uniprot id: A4J2X6
names: Similarity
messages: Belongs to the ParB family.

349161:DRED RS03580
gene id: 349161:DRED_RS03580
uniprot id: A4J2A1
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

349161:DRED RS11705
gene id: 349161:DRED_RS11705
uniprot id: A4J6K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

349161:DRED RS14175
gene id: 349161:DRED_RS14175
uniprot id: A4J7V8
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

349161:DRED RS12465
gene id: 349161:DRED_RS12465
uniprot id: A4J6Z7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

349161:DRED RS09420
gene id: 349161:DRED_RS09420
uniprot id: A4J5D2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

349161:DRED RS12610
gene id: 349161:DRED_RS12610
uniprot id: A4J726
names: Similarity
messages: Belongs to the SAICAR synthetase family.

349161:DRED RS07015
gene id: 349161:DRED_RS07015
uniprot id: A4J425
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS12495
gene id: 349161:DRED_RS12495
uniprot id: A4J703
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

349161:DRED RS16965
gene id: 349161:DRED_RS16965
uniprot id: A4J9D9
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

349161:DRED RS01015
gene id: 349161:DRED_RS01015
uniprot id: A4J0Y3
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

349161:DRED RS05675
gene id: 349161:DRED_RS05675
uniprot id: A4J3D1
names: Similarity
messages: Belongs to the peptidase U62 family.

349161:DRED RS05965
gene id: 349161:DRED_RS05965
uniprot id: A4J3I7
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

349161:DRED RS07850
gene id: 349161:DRED_RS07850
uniprot id: A4J4I3
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

349161:DRED RS01415
gene id: 349161:DRED_RS01415
uniprot id: A4J158
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

349161:DRED RS15480
gene id: 349161:DRED_RS15480
uniprot id: A4J8L0
names: Similarity
messages: Belongs to the manganese catalase family.

349161:DRED RS08740
gene id: 349161:DRED_RS08740
uniprot id: A4J502
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

349161:DRED RS02350
gene id: 349161:DRED_RS02350
uniprot id: A4J1N5
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS08215
gene id: 349161:DRED_RS08215
uniprot id: A4J4Q0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS09915
gene id: 349161:DRED_RS09915
uniprot id: A4J5M4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

349161:DRED RS03230
gene id: 349161:DRED_RS03230
uniprot id: A4J233
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

349161:DRED RS11730
gene id: 349161:DRED_RS11730
uniprot id: A4J6K7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

349161:DRED RS01920
gene id: 349161:DRED_RS01920
uniprot id: A4J1F7
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS16325
gene id: 349161:DRED_RS16325
uniprot id: A4J915
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

349161:DRED RS01715
gene id: 349161:DRED_RS01715
uniprot id: A4J1B8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS15310
gene id: 349161:DRED_RS15310
uniprot id: A4J8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

349161:DRED RS03630
gene id: 349161:DRED_RS03630
uniprot id: A4J2B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

349161:DRED RS09395
gene id: 349161:DRED_RS09395
uniprot id: A4J5C7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
messages: Homodimer.

349161:DRED RS12975
gene id: 349161:DRED_RS12975
uniprot id: A4J796
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

349161:DRED RS04735
gene id: 349161:DRED_RS04735
uniprot id: A4J2W1
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

349161:DRED RS17680
gene id: 349161:DRED_RS17680
uniprot id: A4J9S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

349161:DRED RS08815
gene id: 349161:DRED_RS08815
uniprot id: A4J517
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS15110
gene id: 349161:DRED_RS15110
uniprot id: A4J8D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349161:DRED RS17105
gene id: 349161:DRED_RS17105
uniprot id: A4J9G6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

349161:DRED RS07140
gene id: 349161:DRED_RS07140
uniprot id: A4J448
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

349161:DRED RS09195
gene id: 349161:DRED_RS09195
uniprot id: A4J590
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

349161:DRED RS12220
gene id: 349161:DRED_RS12220
uniprot id: A4J6U9
names: Similarity
messages: Belongs to the DEAD box helicase family.

349161:DRED RS12425
gene id: 349161:DRED_RS12425
uniprot id: A4J6Y9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS13135
gene id: 349161:DRED_RS13135
uniprot id: A4J7C3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

349161:DRED RS00995
gene id: 349161:DRED_RS00995
uniprot id: A4J0X9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation.

349161:DRED RS17650
gene id: 349161:DRED_RS17650
uniprot id: A4J9R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

349161:DRED RS09000
gene id: 349161:DRED_RS09000
uniprot id: A4J551
names: Similarity
messages: Belongs to the phosphosulfolactate synthase family.

349161:DRED RS12530
gene id: 349161:DRED_RS12530
uniprot id: A4J710
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

349161:DRED RS11875
gene id: 349161:DRED_RS11875
uniprot id: A4J6N4
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS03100
gene id: 349161:DRED_RS03100
uniprot id: A4J213
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

349161:DRED RS00980
gene id: 349161:DRED_RS00980
uniprot id: A4J0X6
names: Similarity
messages: Belongs to the ClpA/ClpB family.

349161:DRED RS04090
gene id: 349161:DRED_RS04090
uniprot id: A4J2J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

349161:DRED RS00405
gene id: 349161:DRED_RS00405
uniprot id: A4J0L8
names: Similarity
messages: Belongs to the ThiD family.

349161:DRED RS08465
gene id: 349161:DRED_RS08465
uniprot id: A4J4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

349161:DRED RS09540
gene id: 349161:DRED_RS09540
uniprot id: A4J5F4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349161:DRED RS16865
gene id: 349161:DRED_RS16865
uniprot id: A4J9C1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

349161:DRED RS12155
gene id: 349161:DRED_RS12155
uniprot id: A4J6T7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

349161:DRED RS01295
gene id: 349161:DRED_RS01295
uniprot id: A4J134
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

349161:DRED RS07040
gene id: 349161:DRED_RS07040
uniprot id: A4J430
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

349161:DRED RS15755
gene id: 349161:DRED_RS15755
uniprot id: A4J8Q7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS01705
gene id: 349161:DRED_RS01705
uniprot id: A4J1B6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

349161:DRED RS15260
gene id: 349161:DRED_RS15260
uniprot id: A4J8G5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS08805
gene id: 349161:DRED_RS08805
uniprot id: A4J515
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

349161:DRED RS09435
gene id: 349161:DRED_RS09435
uniprot id: A4J5D4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

349161:DRED RS12625
gene id: 349161:DRED_RS12625
uniprot id: A4J729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

349161:DRED RS05535
gene id: 349161:DRED_RS05535
uniprot id: A4J3A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

349161:DRED RS04460
gene id: 349161:DRED_RS04460
uniprot id: A4J2R4
names: Similarity
messages: Belongs to the peptidase A24 family.

349161:DRED RS09055
gene id: 349161:DRED_RS09055
uniprot id: A4J562
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

349161:DRED RS02435
gene id: 349161:DRED_RS02435
uniprot id: A4J1Q0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS11575
gene id: 349161:DRED_RS11575
uniprot id: A4J6I2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

349161:DRED RS02085
gene id: 349161:DRED_RS02085
uniprot id: A4J1I4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

349161:DRED RS02355
gene id: 349161:DRED_RS02355
uniprot id: A4J1N6
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

349161:DRED RS02210
gene id: 349161:DRED_RS02210
uniprot id: A4J1K7
names: Similarity
messages: Belongs to the RutC family.

349161:DRED RS11915
gene id: 349161:DRED_RS11915
uniprot id: A4J6P2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS10580
gene id: 349161:DRED_RS10580
uniprot id: A4J5Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

349161:DRED RS11905
gene id: 349161:DRED_RS11905
uniprot id: A4J6P0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS06695
gene id: 349161:DRED_RS06695
uniprot id: A4J3W7
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS15630
gene id: 349161:DRED_RS15630
uniprot id: A4J8N4
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS07855
gene id: 349161:DRED_RS07855
uniprot id: A4J4I4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

349161:DRED RS17370
gene id: 349161:DRED_RS17370
uniprot id: A4J9L6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

349161:DRED RS15135
gene id: 349161:DRED_RS15135
uniprot id: A4J8E0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS05605
gene id: 349161:DRED_RS05605
uniprot id: A4J3B7
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS15960
gene id: 349161:DRED_RS15960
uniprot id: A4J8U4
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

349161:DRED RS00755
gene id: 349161:DRED_RS00755
uniprot id: A4J0T7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

349161:DRED RS04690
gene id: 349161:DRED_RS04690
uniprot id: A4J2V3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349161:DRED RS15445
gene id: 349161:DRED_RS15445
uniprot id: A4J8K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

349161:DRED RS01345
gene id: 349161:DRED_RS01345
uniprot id: A4J144
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

349161:DRED RS01165
gene id: 349161:DRED_RS01165
uniprot id: A4J108
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

349161:DRED RS15120
gene id: 349161:DRED_RS15120
uniprot id: A4J8D7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349161:DRED RS03970
gene id: 349161:DRED_RS03970
uniprot id: A4J2H6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

349161:DRED RS13045
gene id: 349161:DRED_RS13045
uniprot id: A4J7B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS09820
gene id: 349161:DRED_RS09820
uniprot id: A4J5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS06095
gene id: 349161:DRED_RS06095
uniprot id: A4J3L1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

349161:DRED RS08835
gene id: 349161:DRED_RS08835
uniprot id: A4J521
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

349161:DRED RS08925
gene id: 349161:DRED_RS08925
uniprot id: A4J538
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

349161:DRED RS08325
gene id: 349161:DRED_RS08325
uniprot id: A4J4S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

349161:DRED RS17350
gene id: 349161:DRED_RS17350
uniprot id: A4J9L2
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

349161:DRED RS13280
gene id: 349161:DRED_RS13280
uniprot id: A4J7F2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

349161:DRED RS12185
gene id: 349161:DRED_RS12185
uniprot id: A4J6U3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

349161:DRED RS16395
gene id: 349161:DRED_RS16395
uniprot id: A4J927
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

349161:DRED RS08810
gene id: 349161:DRED_RS08810
uniprot id: A4J516
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS05860
gene id: 349161:DRED_RS05860
uniprot id: A4J3G8
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS09525
gene id: 349161:DRED_RS09525
uniprot id: A4J5F1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

349161:DRED RS08155
gene id: 349161:DRED_RS08155
uniprot id: A4J4N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS06935
gene id: 349161:DRED_RS06935
uniprot id: A4J411
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

349161:DRED RS01200
gene id: 349161:DRED_RS01200
uniprot id: A4J115
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

349161:DRED RS06365
gene id: 349161:DRED_RS06365
uniprot id: A4J3R3
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS10070
gene id: 349161:DRED_RS10070
uniprot id: A4J5Q4
names: Similarity
messages: Belongs to the histone deacetylase family.

349161:DRED RS05825
gene id: 349161:DRED_RS05825
uniprot id: A4J3G1
names: Similarity
messages: Belongs to the TlyA family.

349161:DRED RS08590
gene id: 349161:DRED_RS08590
uniprot id: A4J4X3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

349161:DRED RS06815
gene id: 349161:DRED_RS06815
uniprot id: A4J3Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

349161:DRED RS09555
gene id: 349161:DRED_RS09555
uniprot id: A4J5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

349161:DRED RS03310
gene id: 349161:DRED_RS03310
uniprot id: A4J247
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

349161:DRED RS13635
gene id: 349161:DRED_RS13635
uniprot id: A4J7M0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

349161:DRED RS10390
gene id: 349161:DRED_RS10390
uniprot id: A4J5W3
names: Similarity
messages: Belongs to the peptidase M16 family.

349161:DRED RS03870
gene id: 349161:DRED_RS03870
uniprot id: A4J2F6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349161:DRED RS09675
gene id: 349161:DRED_RS09675
uniprot id: A4J5H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

349161:DRED RS15270
gene id: 349161:DRED_RS15270
uniprot id: A4J8G7
names: Similarity
messages: Belongs to the AlaDH/PNT family.

349161:DRED RS01055
gene id: 349161:DRED_RS01055
uniprot id: A4J0Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS07930
gene id: 349161:DRED_RS07930
uniprot id: A4J4J9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

349161:DRED RS09095
gene id: 349161:DRED_RS09095
uniprot id: A4J570
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349161:DRED RS15125
gene id: 349161:DRED_RS15125
uniprot id: A4J8D8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

349161:DRED RS03590
gene id: 349161:DRED_RS03590
uniprot id: A4J2A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

349161:DRED RS06270
gene id: 349161:DRED_RS06270
uniprot id: A4J3P5
names: Similarity
messages: Belongs to the UPF0735 family.

349161:DRED RS17360
gene id: 349161:DRED_RS17360
uniprot id: A4J9L4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

349161:DRED RS02605
gene id: 349161:DRED_RS02605
uniprot id: A4J1T0
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

349161:DRED RS08340
gene id: 349161:DRED_RS08340
uniprot id: A4J4S3
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

349161:DRED RS17670
gene id: 349161:DRED_RS17670
uniprot id: A4J9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

349161:DRED RS14750
gene id: 349161:DRED_RS14750
uniprot id: A4J868
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS01355
gene id: 349161:DRED_RS01355
uniprot id: A4J146
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

349161:DRED RS08795
gene id: 349161:DRED_RS08795
uniprot id: A4J513
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

349161:DRED RS06805
gene id: 349161:DRED_RS06805
uniprot id: A4J3Y8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

349161:DRED RS14365
gene id: 349161:DRED_RS14365
uniprot id: A4J7Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate mutase GlmS subunit family.
messages: Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
messages: Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.

349161:DRED RS00915
gene id: 349161:DRED_RS00915
uniprot id: A4J0X0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

349161:DRED RS00260
gene id: 349161:DRED_RS00260
uniprot id: A4J0I9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

349161:DRED RS16155
gene id: 349161:DRED_RS16155
uniprot id: A4J8Y3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

349161:DRED RS07330
gene id: 349161:DRED_RS07330
uniprot id: A4J484
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

349161:DRED RS06710
gene id: 349161:DRED_RS06710
uniprot id: A4J3X0
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

349161:DRED RS11745
gene id: 349161:DRED_RS11745
uniprot id: A4J6L0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

349161:DRED RS01575
gene id: 349161:DRED_RS01575
uniprot id: A4J190
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

349161:DRED RS08750
gene id: 349161:DRED_RS08750
uniprot id: A4J504
names: Similarity
messages: Belongs to the CRISPR-associated Csm3 family.

349161:DRED RS04050
gene id: 349161:DRED_RS04050
uniprot id: A4J2J1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS16580
gene id: 349161:DRED_RS16580
uniprot id: A4J964
names: Function
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.

349161:DRED RS10705
gene id: 349161:DRED_RS10705
uniprot id: A4J623
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

349161:DRED RS08920
gene id: 349161:DRED_RS08920
uniprot id: A4J537
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

349161:DRED RS08015
gene id: 349161:DRED_RS08015
uniprot id: A4J4L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

349161:DRED RS03940
gene id: 349161:DRED_RS03940
uniprot id: A4J2H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS12670
gene id: 349161:DRED_RS12670
uniprot id: A4J738
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

349161:DRED RS09610
gene id: 349161:DRED_RS09610
uniprot id: A4J2V6
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS03850
gene id: 349161:DRED_RS03850
uniprot id: A4J2F3
names: Similarity
messages: Belongs to the UPF0235 family.

349161:DRED RS01475
gene id: 349161:DRED_RS01475
uniprot id: A4J170
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

349161:DRED RS12075
gene id: 349161:DRED_RS12075
uniprot id: A4J6S1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349161:DRED RS12570
gene id: 349161:DRED_RS12570
uniprot id: A4J718
names: Similarity
messages: Belongs to the GARS family.

349161:DRED RS11680
gene id: 349161:DRED_RS11680
uniprot id: A4J6J7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

349161:DRED RS05545
gene id: 349161:DRED_RS05545
uniprot id: A4J3A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

349161:DRED RS05690
gene id: 349161:DRED_RS05690
uniprot id: A4J3D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

349161:DRED RS03500
gene id: 349161:DRED_RS03500
uniprot id: A4J285
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

349161:DRED RS10790
gene id: 349161:DRED_RS10790
uniprot id: A4J637
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

349161:DRED RS15435
gene id: 349161:DRED_RS15435
uniprot id: A4J8K1
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS12505
gene id: 349161:DRED_RS12505
uniprot id: A4J705
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

349161:DRED RS06215
gene id: 349161:DRED_RS06215
uniprot id: A4J3N5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

349161:DRED RS19405
gene id: 349161:DRED_RS19405
uniprot id: A4J823
names: Similarity
messages: Belongs to the UPF0751 family.

349161:DRED RS02415
gene id: 349161:DRED_RS02415
uniprot id: A4J1P8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS15335
gene id: 349161:DRED_RS15335
uniprot id: A4J8I0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

349161:DRED RS01245
gene id: 349161:DRED_RS01245
uniprot id: A4J124
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

349161:DRED RS12840
gene id: 349161:DRED_RS12840
uniprot id: A4J772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

349161:DRED RS06265
gene id: 349161:DRED_RS06265
uniprot id: A4J3P4
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

349161:DRED RS14555
gene id: 349161:DRED_RS14555
uniprot id: A4J829
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

349161:DRED RS01465
gene id: 349161:DRED_RS01465
uniprot id: A4J168
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

349161:DRED RS01490
gene id: 349161:DRED_RS01490
uniprot id: A4J173
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

349161:DRED RS16320
gene id: 349161:DRED_RS16320
uniprot id: A4J914
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

349161:DRED RS16165
gene id: 349161:DRED_RS16165
uniprot id: A4J8Y4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

349161:DRED RS06295
gene id: 349161:DRED_RS06295
uniprot id: A4J3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

349161:DRED RS10950
gene id: 349161:DRED_RS10950
uniprot id: A4J670
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

349161:DRED RS14220
gene id: 349161:DRED_RS14220
uniprot id: A4J7W7
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

349161:DRED RS00035
gene id: 349161:DRED_RS00035
uniprot id: A4J0F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

349161:DRED RS16890
gene id: 349161:DRED_RS16890
uniprot id: A4J9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

349161:DRED RS17660
gene id: 349161:DRED_RS17660
uniprot id: A4J9S1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

349161:DRED RS11885
gene id: 349161:DRED_RS11885
uniprot id: A4J6N6
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS01280
gene id: 349161:DRED_RS01280
uniprot id: A4J131
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

349161:DRED RS09375
gene id: 349161:DRED_RS09375
uniprot id: A4J5C3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

349161:DRED RS11255
gene id: 349161:DRED_RS11255
uniprot id: A4J6D0
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS10360
gene id: 349161:DRED_RS10360
uniprot id: A4J5V7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS10405
gene id: 349161:DRED_RS10405
uniprot id: A4J5W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

349161:DRED RS11430
gene id: 349161:DRED_RS11430
uniprot id: A4J6F9
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS12065
gene id: 349161:DRED_RS12065
uniprot id: A4J6R9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

349161:DRED RS10875
gene id: 349161:DRED_RS10875
uniprot id: A4J655
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS17190
gene id: 349161:DRED_RS17190
uniprot id: A4J9I3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

349161:DRED RS09320
gene id: 349161:DRED_RS09320
uniprot id: A4J5B3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

349161:DRED RS03930
gene id: 349161:DRED_RS03930
uniprot id: A4J2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS05420
gene id: 349161:DRED_RS05420
uniprot id: A4J380
names: Subcellular Location Annotation
messages: Secreted

349161:DRED RS16710
gene id: 349161:DRED_RS16710
uniprot id: A4J990
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

349161:DRED RS17245
gene id: 349161:DRED_RS17245
uniprot id: A4J9J4
names: Subcellular Location Annotation
messages: Cytoplasm

349161:DRED RS05850
gene id: 349161:DRED_RS05850
uniprot id: A4J3G6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

349161:DRED RS11035
gene id: 349161:DRED_RS11035
uniprot id: A4J687
names: Similarity
messages: Belongs to the fabD family.

349161:DRED RS15365
gene id: 349161:DRED_RS15365
uniprot id: A4J8I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

349161:DRED RS11910
gene id: 349161:DRED_RS11910
uniprot id: A4J6P1
names: Similarity
messages: Belongs to the ArsC family.

349161:DRED RS09125
gene id: 349161:DRED_RS09125
uniprot id: A4J576
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS14570
gene id: 349161:DRED_RS14570
uniprot id: A4J832
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

349161:DRED RS03080
gene id: 349161:DRED_RS03080
uniprot id: A4J209
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349161:DRED RS16170
gene id: 349161:DRED_RS16170
uniprot id: A4J8Y5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

349161:DRED RS02800
gene id: 349161:DRED_RS02800
uniprot id: A4J1V6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349161:DRED RS10585
gene id: 349161:DRED_RS10585
uniprot id: A4J5Z9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

349161:DRED RS08295
gene id: 349161:DRED_RS08295
uniprot id: A4J4R4
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

349161:DRED RS03495
gene id: 349161:DRED_RS03495
uniprot id: A4J284
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

349161:DRED RS13410
gene id: 349161:DRED_RS13410
uniprot id: A4J7H8
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS01520
gene id: 349161:DRED_RS01520
uniprot id: A4J179
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

349161:DRED RS02255
gene id: 349161:DRED_RS02255
uniprot id: A4J1L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS07830
gene id: 349161:DRED_RS07830
uniprot id: A4J4H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

349161:DRED RS12390
gene id: 349161:DRED_RS12390
uniprot id: A4J6Y2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

349161:DRED RS08680
gene id: 349161:DRED_RS08680
uniprot id: A4J4Z0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

349161:DRED RS15395
gene id: 349161:DRED_RS15395
uniprot id: A4J8J2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS14240
gene id: 349161:DRED_RS14240
uniprot id: A4J7X1
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS16635
gene id: 349161:DRED_RS16635
uniprot id: A4J975
names: Similarity
messages: Belongs to the phosphohexose mutase family.

349161:DRED RS01120
gene id: 349161:DRED_RS01120
uniprot id: A4J0Z9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

349161:DRED RS02960
gene id: 349161:DRED_RS02960
uniprot id: A4J1Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS13040
gene id: 349161:DRED_RS13040
uniprot id: A4J7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS02925
gene id: 349161:DRED_RS02925
uniprot id: A4J1Y2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

349161:DRED RS17330
gene id: 349161:DRED_RS17330
uniprot id: A4J9K9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS13610
gene id: 349161:DRED_RS13610
uniprot id: A4J7L5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

349161:DRED RS16815
gene id: 349161:DRED_RS16815
uniprot id: A4J9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS07900
gene id: 349161:DRED_RS07900
uniprot id: A4J4J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS06480
gene id: 349161:DRED_RS06480
uniprot id: A4J3T1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS16995
gene id: 349161:DRED_RS16995
uniprot id: A4J9E5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

349161:DRED RS13070
gene id: 349161:DRED_RS13070
uniprot id: A4J7B4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

349161:DRED RS00870
gene id: 349161:DRED_RS00870
uniprot id: A4J0W1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

349161:DRED RS08675
gene id: 349161:DRED_RS08675
uniprot id: A4J4Y9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

349161:DRED RS17540
gene id: 349161:DRED_RS17540
uniprot id: A4J9P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

349161:DRED RS06850
gene id: 349161:DRED_RS06850
uniprot id: A4J3Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS14830
gene id: 349161:DRED_RS14830
uniprot id: A4J884
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS00020
gene id: 349161:DRED_RS00020
uniprot id: A4J0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

349161:DRED RS05760
gene id: 349161:DRED_RS05760
uniprot id: A4J3E8
names: Similarity
messages: Belongs to the asp23 family.

349161:DRED RS01435
gene id: 349161:DRED_RS01435
uniprot id: A4J162
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

349161:DRED RS16780
gene id: 349161:DRED_RS16780
uniprot id: A4J9A4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

349161:DRED RS09060
gene id: 349161:DRED_RS09060
uniprot id: A4J563
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

349161:DRED RS09035
gene id: 349161:DRED_RS09035
uniprot id: A4J558
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS09150
gene id: 349161:DRED_RS09150
uniprot id: A4J581
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

349161:DRED RS12825
gene id: 349161:DRED_RS12825
uniprot id: A4J769
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

349161:DRED RS11400
gene id: 349161:DRED_RS11400
uniprot id: A4J6F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

349161:DRED RS09490
gene id: 349161:DRED_RS09490
uniprot id: A4J5E5
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

349161:DRED RS17640
gene id: 349161:DRED_RS17640
uniprot id: A4J9R7
names: Similarity
messages: Belongs to the ParB family.

349161:DRED RS09720
gene id: 349161:DRED_RS09720
uniprot id: A4J5I8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

349161:DRED RS07700
gene id: 349161:DRED_RS07700
uniprot id: A4J4F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS15390
gene id: 349161:DRED_RS15390
uniprot id: A4J8J1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

349161:DRED RS03365
gene id: 349161:DRED_RS03365
uniprot id: A4J259
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

349161:DRED RS11030
gene id: 349161:DRED_RS11030
uniprot id: A4J686
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

349161:DRED RS16360
gene id: 349161:DRED_RS16360
uniprot id: A4J921
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

349161:DRED RS15295
gene id: 349161:DRED_RS15295
uniprot id: A4J8H2
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

349161:DRED RS05240
gene id: 349161:DRED_RS05240
uniprot id: A4J345
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

349161:DRED RS16745
gene id: 349161:DRED_RS16745
uniprot id: A4J997
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS07300
gene id: 349161:DRED_RS07300
uniprot id: A4J479
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

349161:DRED RS04780
gene id: 349161:DRED_RS04780
uniprot id: A4J2V6
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS15105
gene id: 349161:DRED_RS15105
uniprot id: A4J8D4
names: Similarity
messages: Belongs to the OsmC/Ohr family.

349161:DRED RS17090
gene id: 349161:DRED_RS17090
uniprot id: A4J9G3
names: Similarity
messages: Belongs to the peptidase M29 family.

349161:DRED RS03905
gene id: 349161:DRED_RS03905
uniprot id: A4J2G3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

349161:DRED RS13250
gene id: 349161:DRED_RS13250
uniprot id: A4J7E6
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS10005
gene id: 349161:DRED_RS10005
uniprot id: A4J5P2
names: Similarity
messages: Belongs to the class-I fumarase family.

349161:DRED RS02150
gene id: 349161:DRED_RS02150
uniprot id: A4J1J7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349161:DRED RS10460
gene id: 349161:DRED_RS10460
uniprot id: A4J5X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

349161:DRED RS01935
gene id: 349161:DRED_RS01935
uniprot id: A4J1G0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

349161:DRED RS04060
gene id: 349161:DRED_RS04060
uniprot id: A4J2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

349161:DRED RS15225
gene id: 349161:DRED_RS15225
uniprot id: A4J8F8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349161:DRED RS12695
gene id: 349161:DRED_RS12695
uniprot id: A4J743
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

349161:DRED RS16365
gene id: 349161:DRED_RS16365
uniprot id: A4J922
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

349161:DRED RS13580
gene id: 349161:DRED_RS13580
uniprot id: A4J7K9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

349161:DRED RS07000
gene id: 349161:DRED_RS07000
uniprot id: A4J422
names: Similarity
messages: Belongs to the EutP/PduV family.

349161:DRED RS07560
gene id: 349161:DRED_RS07560
uniprot id: A4J4C5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

349161:DRED RS18055
gene id: 349161:DRED_RS18055
uniprot id: A4J9S5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

349161:DRED RS12620
gene id: 349161:DRED_RS12620
uniprot id: A4J728
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

349161:DRED RS10890
gene id: 349161:DRED_RS10890
uniprot id: A4J658
names: Function
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

349161:DRED RS05805
gene id: 349161:DRED_RS05805
uniprot id: A4J3F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

349161:DRED RS07375
gene id: 349161:DRED_RS07375
uniprot id: A4J491
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

349161:DRED RS17465
gene id: 349161:DRED_RS17465
uniprot id: A4J9N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS11750
gene id: 349161:DRED_RS11750
uniprot id: A4J6L1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

349161:DRED RS10940
gene id: 349161:DRED_RS10940
uniprot id: A4J668
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

349161:DRED RS02465
gene id: 349161:DRED_RS02465
uniprot id: A4J1Q5
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

349161:DRED RS11815
gene id: 349161:DRED_RS11815
uniprot id: A4J6M3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS04925
gene id: 349161:DRED_RS04925
uniprot id: A4J2Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

349161:DRED RS15360
gene id: 349161:DRED_RS15360
uniprot id: A4J8I5
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

349161:DRED RS01180
gene id: 349161:DRED_RS01180
uniprot id: A4J111
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

349161:DRED RS07430
gene id: 349161:DRED_RS07430
uniprot id: A4J499
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

349161:DRED RS09140
gene id: 349161:DRED_RS09140
uniprot id: A4J579
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

349161:DRED RS03830
gene id: 349161:DRED_RS03830
uniprot id: A4J2E9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

349161:DRED RS17305
gene id: 349161:DRED_RS17305
uniprot id: A4J9K3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

349161:DRED RS08885
gene id: 349161:DRED_RS08885
uniprot id: A4J530
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

349161:DRED RS12520
gene id: 349161:DRED_RS12520
uniprot id: A4J708
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

349161:DRED RS12475
gene id: 349161:DRED_RS12475
uniprot id: A4J6Z9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

349161:DRED RS00435
gene id: 349161:DRED_RS00435
uniprot id: A4J0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

349161:DRED RS09475
gene id: 349161:DRED_RS09475
uniprot id: A4J5E2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

349161:DRED RS02275
gene id: 349161:DRED_RS02275
uniprot id: A4J1M0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

349161:DRED RS03285
gene id: 349161:DRED_RS03285
uniprot id: A4J242
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349161:DRED RS13380
gene id: 349161:DRED_RS13380
uniprot id: A4J7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

349161:DRED RS01515
gene id: 349161:DRED_RS01515
uniprot id: A4J178
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

349161:DRED RS03300
gene id: 349161:DRED_RS03300
uniprot id: A4J245
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

349161:DRED RS11205
gene id: 349161:DRED_RS11205
uniprot id: A4J6C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PstS family.
messages: Cell membrane
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

349161:DRED RS03680
gene id: 349161:DRED_RS03680
uniprot id: A4J2C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

349161:DRED RS14440
gene id: 349161:DRED_RS14440
uniprot id: A4J807
names: Similarity
messages: Belongs to the CobH/CbiC family.

349161:DRED RS13150
gene id: 349161:DRED_RS13150
uniprot id: A4J7C6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

349161:DRED RS10680
gene id: 349161:DRED_RS10680
uniprot id: A4J618
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

349161:DRED RS11230
gene id: 349161:DRED_RS11230
uniprot id: A4J6C5
names: Similarity
messages: Belongs to the peptidase A24 family.

349161:DRED RS14975
gene id: 349161:DRED_RS14975
uniprot id: A4J8A8
names: Similarity
messages: Belongs to the glutamine synthetase family.

349161:DRED RS17665
gene id: 349161:DRED_RS17665
uniprot id: A4J9S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

349161:DRED RS12970
gene id: 349161:DRED_RS12970
uniprot id: A4J795
names: Similarity
messages: Belongs to the FlgM family.

349161:DRED RS12880
gene id: 349161:DRED_RS12880
uniprot id: A4J780
names: Similarity
messages: Belongs to the HepT RNase toxin family.

349161:DRED RS12665
gene id: 349161:DRED_RS12665
uniprot id: A4J737
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

349161:DRED RS08830
gene id: 349161:DRED_RS08830
uniprot id: A4J520
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS07690
gene id: 349161:DRED_RS07690
uniprot id: A4J4F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS11010
gene id: 349161:DRED_RS11010
uniprot id: A4J682
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

349161:DRED RS05345
gene id: 349161:DRED_RS05345
uniprot id: A4J365
names: Similarity
messages: Belongs to the UPF0758 family.

349161:DRED RS08745
gene id: 349161:DRED_RS08745
uniprot id: A4J503
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm2 family.
messages: This subunit may be involved in monitoring complementarity of crRNA and target RNA.

349161:DRED RS12180
gene id: 349161:DRED_RS12180
uniprot id: A4J6U2
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

349161:DRED RS00675
gene id: 349161:DRED_RS00675
uniprot id: A4J0S2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

349161:DRED RS12690
gene id: 349161:DRED_RS12690
uniprot id: A4J742
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

349161:DRED RS00075
gene id: 349161:DRED_RS00075
uniprot id: A4J0G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

349161:DRED RS00140
gene id: 349161:DRED_RS00140
uniprot id: A4J0G7
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS12850
gene id: 349161:DRED_RS12850
uniprot id: A4J774
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

349161:DRED RS04105
gene id: 349161:DRED_RS04105
uniprot id: A4J2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

349161:DRED RS12335
gene id: 349161:DRED_RS12335
uniprot id: A4J6X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

349161:DRED RS04025
gene id: 349161:DRED_RS04025
uniprot id: A4J2I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

349161:DRED RS11005
gene id: 349161:DRED_RS11005
uniprot id: A4J681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

349161:DRED RS15100
gene id: 349161:DRED_RS15100
uniprot id: A4J8D3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

349161:DRED RS07025
gene id: 349161:DRED_RS07025
uniprot id: A4J427
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutC family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

349161:DRED RS01540
gene id: 349161:DRED_RS01540
uniprot id: A4J183
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

349161:DRED RS07170
gene id: 349161:DRED_RS07170
uniprot id: A4J454
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

349161:DRED RS03880
gene id: 349161:DRED_RS03880
uniprot id: A4J2F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

349161:DRED RS06105
gene id: 349161:DRED_RS06105
uniprot id: A4J3L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

349161:DRED RS01410
gene id: 349161:DRED_RS01410
uniprot id: A4J157
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

349161:DRED RS07110
gene id: 349161:DRED_RS07110
uniprot id: A4J443
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS10240
gene id: 349161:DRED_RS10240
uniprot id: A4J5T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

349161:DRED RS01730
gene id: 349161:DRED_RS01730
uniprot id: A4J1C1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS16725
gene id: 349161:DRED_RS16725
uniprot id: A4J993
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS17450
gene id: 349161:DRED_RS17450
uniprot id: A4J9N3
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

349161:DRED RS01885
gene id: 349161:DRED_RS01885
uniprot id: A4J1F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

349161:DRED RS01020
gene id: 349161:DRED_RS01020
uniprot id: A4J0Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

349161:DRED RS06210
gene id: 349161:DRED_RS06210
uniprot id: A4J3N4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

349161:DRED RS03775
gene id: 349161:DRED_RS03775
uniprot id: A4J2D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

349161:DRED RS03605
gene id: 349161:DRED_RS03605
uniprot id: A4J2A6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS12560
gene id: 349161:DRED_RS12560
uniprot id: A4J716
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

349161:DRED RS01390
gene id: 349161:DRED_RS01390
uniprot id: A4J153
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

349161:DRED RS08595
gene id: 349161:DRED_RS08595
uniprot id: A4J4X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

349161:DRED RS03330
gene id: 349161:DRED_RS03330
uniprot id: A4J251
names: Similarity
messages: Belongs to the RutC family.

349161:DRED RS00815
gene id: 349161:DRED_RS00815
uniprot id: A4J0V0
names: Similarity
messages: Belongs to the DHPS family.

349161:DRED RS06420
gene id: 349161:DRED_RS06420
uniprot id: A4J3S2
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

349161:DRED RS03075
gene id: 349161:DRED_RS03075
uniprot id: A4J208
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS17265
gene id: 349161:DRED_RS17265
uniprot id: A4J9J6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

349161:DRED RS07865
gene id: 349161:DRED_RS07865
uniprot id: A4J4I6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

349161:DRED RS07305
gene id: 349161:DRED_RS07305
uniprot id: A4J480
names: Subcellular Location Annotation
messages: Cell membrane

349161:DRED RS13470
gene id: 349161:DRED_RS13470
uniprot id: A4J7I8
names: Similarity
messages: Belongs to the SfsA family.

349161:DRED RS11725
gene id: 349161:DRED_RS11725
uniprot id: A4J6K6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

349161:DRED RS13115
gene id: 349161:DRED_RS13115
uniprot id: A4J7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

349161:DRED RS02500
gene id: 349161:DRED_RS02500
uniprot id: A4J1R1
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

349161:DRED RS11755
gene id: 349161:DRED_RS11755
uniprot id: A4J6L2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

349161:DRED RS14125
gene id: 349161:DRED_RS14125
uniprot id: A4J7U8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

349161:DRED RS14590
gene id: 349161:DRED_RS14590
uniprot id: A4J836
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

349161:DRED RS16665
gene id: 349161:DRED_RS16665
uniprot id: A4J981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

349161:DRED RS08500
gene id: 349161:DRED_RS08500
uniprot id: A4J4V6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS00030
gene id: 349161:DRED_RS00030
uniprot id: A4J0F5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

349161:DRED RS10270
gene id: 349161:DRED_RS10270
uniprot id: A4J5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

349161:DRED RS12810
gene id: 349161:DRED_RS12810
uniprot id: A4J766
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

349161:DRED RS02295
gene id: 349161:DRED_RS02295
uniprot id: A4J1M4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS17725
gene id: 349161:DRED_RS17725
uniprot id: A4J1C9
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

349161:DRED RS16800
gene id: 349161:DRED_RS16800
uniprot id: A4J9A8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

349161:DRED RS12460
gene id: 349161:DRED_RS12460
uniprot id: A4J6Z6
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

349161:DRED RS11620
gene id: 349161:DRED_RS11620
uniprot id: A4J6I9
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS10575
gene id: 349161:DRED_RS10575
uniprot id: A4J5Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

349161:DRED RS12995
gene id: 349161:DRED_RS12995
uniprot id: A4J7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

349161:DRED RS09630
gene id: 349161:DRED_RS09630
uniprot id: A4J5H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS16495
gene id: 349161:DRED_RS16495
uniprot id: A4J947
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

349161:DRED RS09390
gene id: 349161:DRED_RS09390
uniprot id: A4J5C6
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

349161:DRED RS08665
gene id: 349161:DRED_RS08665
uniprot id: A4J4Y7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS09535
gene id: 349161:DRED_RS09535
uniprot id: A4J5F3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349161:DRED RS14995
gene id: 349161:DRED_RS14995
uniprot id: A4J8B2
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS10500
gene id: 349161:DRED_RS10500
uniprot id: A4J5Y3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

349161:DRED RS01190
gene id: 349161:DRED_RS01190
uniprot id: A4J113
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

349161:DRED RS14185
gene id: 349161:DRED_RS14185
uniprot id: A4J7W0
names: Similarity
messages: Belongs to the UPF0111 family.

349161:DRED RS07795
gene id: 349161:DRED_RS07795
uniprot id: A4J4H2
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS01160
gene id: 349161:DRED_RS01160
uniprot id: A4J107
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

349161:DRED RS11955
gene id: 349161:DRED_RS11955
uniprot id: A4J6Q0
names: Similarity
messages: Belongs to the leucine-binding protein family.

349161:DRED RS12525
gene id: 349161:DRED_RS12525
uniprot id: A4J709
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

349161:DRED RS12755
gene id: 349161:DRED_RS12755
uniprot id: A4J755
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

349161:DRED RS16500
gene id: 349161:DRED_RS16500
uniprot id: A4J948
names: Similarity
messages: Belongs to the peptidase S8 family.

349161:DRED RS07465
gene id: 349161:DRED_RS07465
uniprot id: A4J4A6
names: Similarity
messages: Belongs to the threonine synthase family.

349161:DRED RS17010
gene id: 349161:DRED_RS17010
uniprot id: A4J9E8
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS15025
gene id: 349161:DRED_RS15025
uniprot id: A4J8B8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

349161:DRED RS07925
gene id: 349161:DRED_RS07925
uniprot id: A4J4J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

349161:DRED RS00320
gene id: 349161:DRED_RS00320
uniprot id: A4J0K1
names: Similarity
messages: Belongs to the GerABKA family.

349161:DRED RS15890
gene id: 349161:DRED_RS15890
uniprot id: A4J8T1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS00920
gene id: 349161:DRED_RS00920
uniprot id: A4J0X1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS01910
gene id: 349161:DRED_RS01910
uniprot id: A4J1F5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349161:DRED RS12245
gene id: 349161:DRED_RS12245
uniprot id: A4J6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

349161:DRED RS03900
gene id: 349161:DRED_RS03900
uniprot id: A4J2G2
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS03340
gene id: 349161:DRED_RS03340
uniprot id: A4J253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

349161:DRED RS03555
gene id: 349161:DRED_RS03555
uniprot id: A4J296
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

349161:DRED RS15665
gene id: 349161:DRED_RS15665
uniprot id: A4J8P1
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

349161:DRED RS16920
gene id: 349161:DRED_RS16920
uniprot id: A4J9D0
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS01695
gene id: 349161:DRED_RS01695
uniprot id: A4J1B4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349161:DRED RS15330
gene id: 349161:DRED_RS15330
uniprot id: A4J8H9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

349161:DRED RS01745
gene id: 349161:DRED_RS01745
uniprot id: A4J1C3
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS08820
gene id: 349161:DRED_RS08820
uniprot id: A4J518
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

349161:DRED RS16660
gene id: 349161:DRED_RS16660
uniprot id: A4J980
names: Similarity
messages: Belongs to the ABC transporter superfamily.

349161:DRED RS00905
gene id: 349161:DRED_RS00905
uniprot id: A4J0W8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

349161:DRED RS09985
gene id: 349161:DRED_RS09985
uniprot id: A4J5N8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

349161:DRED RS13300
gene id: 349161:DRED_RS13300
uniprot id: A4J7F6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

349161:DRED RS08865
gene id: 349161:DRED_RS08865
uniprot id: A4J527
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

349161:DRED RS09330
gene id: 349161:DRED_RS09330
uniprot id: A4J5B5
names: Function
names: Similarity
messages: 3'-5' exonuclease.
messages: Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.

349161:DRED RS09560
gene id: 349161:DRED_RS09560
uniprot id: A4J5F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

349161:DRED RS06015
gene id: 349161:DRED_RS06015
uniprot id: A4J3J7
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

349161:DRED RS12815
gene id: 349161:DRED_RS12815
uniprot id: A4J767
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

349161:DRED RS17040
gene id: 349161:DRED_RS17040
uniprot id: A4J9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS01260
gene id: 349161:DRED_RS01260
uniprot id: A4J127
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

349161:DRED RS01045
gene id: 349161:DRED_RS01045
uniprot id: A4J0Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS14165
gene id: 349161:DRED_RS14165
uniprot id: A4J7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS14990
gene id: 349161:DRED_RS14990
uniprot id: A4J8B1
names: Similarity
messages: Belongs to the glutamine synthetase family.

349161:DRED RS15015
gene id: 349161:DRED_RS15015
uniprot id: A4J8B6
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

349161:DRED RS14640
gene id: 349161:DRED_RS14640
uniprot id: A4J846
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS07785
gene id: 349161:DRED_RS07785
uniprot id: A4J4H0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349161:DRED RS12275
gene id: 349161:DRED_RS12275
uniprot id: A4J6W0
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS00500
gene id: 349161:DRED_RS00500
uniprot id: A4J0N6
names: Similarity
messages: Belongs to the peptidase S8 family.

349161:DRED RS03660
gene id: 349161:DRED_RS03660
uniprot id: A4J2B7
names: Similarity
messages: Belongs to the UPF0749 family.

349161:DRED RS16830
gene id: 349161:DRED_RS16830
uniprot id: A4J9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

349161:DRED RS01135
gene id: 349161:DRED_RS01135
uniprot id: A4J102
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

349161:DRED RS10565
gene id: 349161:DRED_RS10565
uniprot id: A4J5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

349161:DRED RS09405
gene id: 349161:DRED_RS09405
uniprot id: A4J5C9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS14210
gene id: 349161:DRED_RS14210
uniprot id: A4J7W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

349161:DRED RS11200
gene id: 349161:DRED_RS11200
uniprot id: A4J6B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane

349161:DRED RS05895
gene id: 349161:DRED_RS05895
uniprot id: A4J3H4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

349161:DRED RS03645
gene id: 349161:DRED_RS03645
uniprot id: A4J2B4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS12510
gene id: 349161:DRED_RS12510
uniprot id: A4J706
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

349161:DRED RS12295
gene id: 349161:DRED_RS12295
uniprot id: A4J6W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

349161:DRED RS17970
gene id: 349161:DRED_RS17970
uniprot id: A4J7S4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS10540
gene id: 349161:DRED_RS10540
uniprot id: A4J5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

349161:DRED RS01300
gene id: 349161:DRED_RS01300
uniprot id: A4J135
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

349161:DRED RS15275
gene id: 349161:DRED_RS15275
uniprot id: A4J8G8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS01220
gene id: 349161:DRED_RS01220
uniprot id: A4J119
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

349161:DRED RS12575
gene id: 349161:DRED_RS12575
uniprot id: A4J719
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

349161:DRED RS10945
gene id: 349161:DRED_RS10945
uniprot id: A4J669
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

349161:DRED RS04130
gene id: 349161:DRED_RS04130
uniprot id: A4J2K8
names: Similarity
messages: Belongs to the UPF0297 family.

349161:DRED RS11250
gene id: 349161:DRED_RS11250
uniprot id: A4J6C9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS15250
gene id: 349161:DRED_RS15250
uniprot id: A4J8G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS10570
gene id: 349161:DRED_RS10570
uniprot id: A4J5Z6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

349161:DRED RS09760
gene id: 349161:DRED_RS09760
uniprot id: A4J5J6
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

349161:DRED RS14190
gene id: 349161:DRED_RS14190
uniprot id: A4J7W1
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS05305
gene id: 349161:DRED_RS05305
uniprot id: A4J358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

349161:DRED RS03505
gene id: 349161:DRED_RS03505
uniprot id: A4J286
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

349161:DRED RS03875
gene id: 349161:DRED_RS03875
uniprot id: A4J2F7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349161:DRED RS17115
gene id: 349161:DRED_RS17115
uniprot id: A4J9G8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

349161:DRED RS01765
gene id: 349161:DRED_RS01765
uniprot id: A4J1C7
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS16770
gene id: 349161:DRED_RS16770
uniprot id: A4J9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

349161:DRED RS11720
gene id: 349161:DRED_RS11720
uniprot id: A4J6K5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

349161:DRED RS02835
gene id: 349161:DRED_RS02835
uniprot id: A4J1W4
names: Similarity
messages: Belongs to the AAA ATPase family.

349161:DRED RS01275
gene id: 349161:DRED_RS01275
uniprot id: A4J130
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

349161:DRED RS10870
gene id: 349161:DRED_RS10870
uniprot id: A4J654
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS10430
gene id: 349161:DRED_RS10430
uniprot id: A4J5W9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

349161:DRED RS09855
gene id: 349161:DRED_RS09855
uniprot id: A4J5L3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS16505
gene id: 349161:DRED_RS16505
uniprot id: A4J949
names: Similarity
messages: Belongs to the phosphohexose mutase family.

349161:DRED RS11100
gene id: 349161:DRED_RS11100
uniprot id: A4J6A0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

349161:DRED RS11265
gene id: 349161:DRED_RS11265
uniprot id: A4J6D2
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS09550
gene id: 349161:DRED_RS09550
uniprot id: A4J5F6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349161:DRED RS07970
gene id: 349161:DRED_RS07970
uniprot id: A4J4K7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

349161:DRED RS01495
gene id: 349161:DRED_RS01495
uniprot id: A4J174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

349161:DRED RS12480
gene id: 349161:DRED_RS12480
uniprot id: A4J700
names: Similarity
messages: Belongs to the RutC family.

349161:DRED RS16825
gene id: 349161:DRED_RS16825
uniprot id: A4J9B3
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

349161:DRED RS16125
gene id: 349161:DRED_RS16125
uniprot id: A4J8X7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

349161:DRED RS14135
gene id: 349161:DRED_RS14135
uniprot id: A4J7V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

349161:DRED RS16225
gene id: 349161:DRED_RS16225
uniprot id: A4J8Z6
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

349161:DRED RS07645
gene id: 349161:DRED_RS07645
uniprot id: A4J4E2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

349161:DRED RS13245
gene id: 349161:DRED_RS13245
uniprot id: A4J7E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

349161:DRED RS06725
gene id: 349161:DRED_RS06725
uniprot id: A4J3X3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

349161:DRED RS07845
gene id: 349161:DRED_RS07845
uniprot id: A4J4I2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

349161:DRED RS03585
gene id: 349161:DRED_RS03585
uniprot id: A4J2A2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

349161:DRED RS16400
gene id: 349161:DRED_RS16400
uniprot id: A4J928
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

349161:DRED RS16930
gene id: 349161:DRED_RS16930
uniprot id: A4J9D2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS06100
gene id: 349161:DRED_RS06100
uniprot id: A4J3L2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

349161:DRED RS06285
gene id: 349161:DRED_RS06285
uniprot id: A4J3P8
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

349161:DRED RS13180
gene id: 349161:DRED_RS13180
uniprot id: A4J7D2
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

349161:DRED RS01340
gene id: 349161:DRED_RS01340
uniprot id: A4J143
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS04065
gene id: 349161:DRED_RS04065
uniprot id: A4J2J4
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS01050
gene id: 349161:DRED_RS01050
uniprot id: A4J0Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

349161:DRED RS10925
gene id: 349161:DRED_RS10925
uniprot id: A4J665
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

349161:DRED RS01215
gene id: 349161:DRED_RS01215
uniprot id: A4J118
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

349161:DRED RS04905
gene id: 349161:DRED_RS04905
uniprot id: A4J2Y7
names: Similarity
messages: Belongs to the thioredoxin family.

349161:DRED RS10985
gene id: 349161:DRED_RS10985
uniprot id: A4J677
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

349161:DRED RS09315
gene id: 349161:DRED_RS09315
uniprot id: A4J5B2
names: Similarity
messages: Belongs to the UPF0173 family.

349161:DRED RS10955
gene id: 349161:DRED_RS10955
uniprot id: A4J671
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

349161:DRED RS17575
gene id: 349161:DRED_RS17575
uniprot id: A4J9Q4
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS08090
gene id: 349161:DRED_RS08090
uniprot id: A4J4M8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS16785
gene id: 349161:DRED_RS16785
uniprot id: A4J9A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

349161:DRED RS10490
gene id: 349161:DRED_RS10490
uniprot id: A4J5Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

349161:DRED RS09615
gene id: 349161:DRED_RS09615
uniprot id: A4J5G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

349161:DRED RS15680
gene id: 349161:DRED_RS15680
uniprot id: A4J8P4
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS10930
gene id: 349161:DRED_RS10930
uniprot id: A4J666
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

349161:DRED RS00245
gene id: 349161:DRED_RS00245
uniprot id: A4J0I7
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

349161:DRED RS03720
gene id: 349161:DRED_RS03720
uniprot id: A4J2C8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

349161:DRED RS15910
gene id: 349161:DRED_RS15910
uniprot id: A4J8T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

349161:DRED RS14170
gene id: 349161:DRED_RS14170
uniprot id: A4J7V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

349161:DRED RS07125
gene id: 349161:DRED_RS07125
uniprot id: A4J446
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

349161:DRED RS15670
gene id: 349161:DRED_RS15670
uniprot id: A4J8P2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

349161:DRED RS10350
gene id: 349161:DRED_RS10350
uniprot id: A4J5V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

349161:DRED RS15660
gene id: 349161:DRED_RS15660
uniprot id: A4J8P0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

349161:DRED RS09430
gene id: 349161:DRED_RS09430
uniprot id: A4J5D3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS03460
gene id: 349161:DRED_RS03460
uniprot id: A4J278
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

349161:DRED RS00345
gene id: 349161:DRED_RS00345
uniprot id: A4J0K6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

349161:DRED RS06275
gene id: 349161:DRED_RS06275
uniprot id: A4J3P6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

349161:DRED RS13270
gene id: 349161:DRED_RS13270
uniprot id: A4J7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

349161:DRED RS10320
gene id: 349161:DRED_RS10320
uniprot id: A4J5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

349161:DRED RS10465
gene id: 349161:DRED_RS10465
uniprot id: A4J5X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

349161:DRED RS08205
gene id: 349161:DRED_RS08205
uniprot id: A4J4P8
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS01950
gene id: 349161:DRED_RS01950
uniprot id: A4J1G3
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

349161:DRED RS17590
gene id: 349161:DRED_RS17590
uniprot id: A4J9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

349161:DRED RS16680
gene id: 349161:DRED_RS16680
uniprot id: A4J984
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS08220
gene id: 349161:DRED_RS08220
uniprot id: A4J4Q1
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS09740
gene id: 349161:DRED_RS09740
uniprot id: A4J5J2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS11550
gene id: 349161:DRED_RS11550
uniprot id: A4J6H7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

349161:DRED RS14655
gene id: 349161:DRED_RS14655
uniprot id: A4J849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS16750
gene id: 349161:DRED_RS16750
uniprot id: A4J998
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

349161:DRED RS14325
gene id: 349161:DRED_RS14325
uniprot id: A4J7Y7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

349161:DRED RS15925
gene id: 349161:DRED_RS15925
uniprot id: A4J8T7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

349161:DRED RS03475
gene id: 349161:DRED_RS03475
uniprot id: A4J280
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS12230
gene id: 349161:DRED_RS12230
uniprot id: A4J6V1
names: Similarity
messages: Belongs to the manganese catalase family.

349161:DRED RS16760
gene id: 349161:DRED_RS16760
uniprot id: A4J9A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

349161:DRED RS12700
gene id: 349161:DRED_RS12700
uniprot id: A4J744
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

349161:DRED RS11020
gene id: 349161:DRED_RS11020
uniprot id: A4J684
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

349161:DRED RS03885
gene id: 349161:DRED_RS03885
uniprot id: A4J2F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

349161:DRED RS03690
gene id: 349161:DRED_RS03690
uniprot id: A4J2C3
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

349161:DRED RS12270
gene id: 349161:DRED_RS12270
uniprot id: A4J6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

349161:DRED RS10515
gene id: 349161:DRED_RS10515
uniprot id: A4J5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

349161:DRED RS10410
gene id: 349161:DRED_RS10410
uniprot id: A4J5W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

349161:DRED RS09175
gene id: 349161:DRED_RS09175
uniprot id: A4J586
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS14685
gene id: 349161:DRED_RS14685
uniprot id: A4J187
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS13420
gene id: 349161:DRED_RS13420
uniprot id: A4J7I0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS16565
gene id: 349161:DRED_RS16565
uniprot id: A4J961
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

349161:DRED RS05795
gene id: 349161:DRED_RS05795
uniprot id: A4J3F5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

349161:DRED RS01925
gene id: 349161:DRED_RS01925
uniprot id: A4J1F8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

349161:DRED RS01170
gene id: 349161:DRED_RS01170
uniprot id: A4J0Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

349161:DRED RS03225
gene id: 349161:DRED_RS03225
uniprot id: A4J232
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

349161:DRED RS00605
gene id: 349161:DRED_RS00605
uniprot id: A4J0Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

349161:DRED RS14230
gene id: 349161:DRED_RS14230
uniprot id: A4J7W9
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

349161:DRED RS12305
gene id: 349161:DRED_RS12305
uniprot id: A4J6W6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

349161:DRED RS06355
gene id: 349161:DRED_RS06355
uniprot id: A4J3R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349161:DRED RS10105
gene id: 349161:DRED_RS10105
uniprot id: A4J5R1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349161:DRED RS05950
gene id: 349161:DRED_RS05950
uniprot id: A4J3I4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

349161:DRED RS15495
gene id: 349161:DRED_RS15495
uniprot id: A4J8L3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS05845
gene id: 349161:DRED_RS05845
uniprot id: A4J3G5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

349161:DRED RS10250
gene id: 349161:DRED_RS10250
uniprot id: A4J5T9
names: Similarity
messages: Belongs to the DEAD box helicase family.

349161:DRED RS05810
gene id: 349161:DRED_RS05810
uniprot id: A4J3F8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

349161:DRED RS03430
gene id: 349161:DRED_RS03430
uniprot id: A4J272
names: Similarity
messages: Belongs to the sulfate adenylyltransferase family.

349161:DRED RS08735
gene id: 349161:DRED_RS08735
uniprot id: A4J500
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

349161:DRED RS04960
gene id: 349161:DRED_RS04960
uniprot id: A4J2Z7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

349161:DRED RS15585
gene id: 349161:DRED_RS15585
uniprot id: A4J8M5
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS12845
gene id: 349161:DRED_RS12845
uniprot id: A4J773
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

349161:DRED RS05440
gene id: 349161:DRED_RS05440
uniprot id: A4J384
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

349161:DRED RS02090
gene id: 349161:DRED_RS02090
uniprot id: A4J1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS00865
gene id: 349161:DRED_RS00865
uniprot id: A4J0W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

349161:DRED RS02540
gene id: 349161:DRED_RS02540
uniprot id: A4J1R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS09090
gene id: 349161:DRED_RS09090
uniprot id: A4J569
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS13630
gene id: 349161:DRED_RS13630
uniprot id: A4J7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

349161:DRED RS08900
gene id: 349161:DRED_RS08900
uniprot id: A4J533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

349161:DRED RS00715
gene id: 349161:DRED_RS00715
uniprot id: A4J0T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349161:DRED RS09295
gene id: 349161:DRED_RS09295
uniprot id: A4J5A8
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

349161:DRED RS12750
gene id: 349161:DRED_RS12750
uniprot id: A4J754
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

349161:DRED RS17415
gene id: 349161:DRED_RS17415
uniprot id: A4J9M5
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-822 that is involved in catalysis.

349161:DRED RS01580
gene id: 349161:DRED_RS01580
uniprot id: A4J191
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS01330
gene id: 349161:DRED_RS01330
uniprot id: A4J141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

349161:DRED RS00305
gene id: 349161:DRED_RS00305
uniprot id: A4J0J8
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

349161:DRED RS16850
gene id: 349161:DRED_RS16850
uniprot id: A4J9B8
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

349161:DRED RS16895
gene id: 349161:DRED_RS16895
uniprot id: A4J9C5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

349161:DRED RS07250
gene id: 349161:DRED_RS07250
uniprot id: A4J470
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS13400
gene id: 349161:DRED_RS13400
uniprot id: A4J7H6
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

349161:DRED RS01175
gene id: 349161:DRED_RS01175
uniprot id: A4J110
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

349161:DRED RS00710
gene id: 349161:DRED_RS00710
uniprot id: A4J0S9
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349161:DRED RS11390
gene id: 349161:DRED_RS11390
uniprot id: A4J6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS15265
gene id: 349161:DRED_RS15265
uniprot id: A4J8G6
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

349161:DRED RS09575
gene id: 349161:DRED_RS09575
uniprot id: A4J5G1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

349161:DRED RS10755
gene id: 349161:DRED_RS10755
uniprot id: A4J632
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

349161:DRED RS10045
gene id: 349161:DRED_RS10045
uniprot id: A4J5P9
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

349161:DRED RS07165
gene id: 349161:DRED_RS07165
uniprot id: A4J453
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

349161:DRED RS08645
gene id: 349161:DRED_RS08645
uniprot id: A4J4Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS03935
gene id: 349161:DRED_RS03935
uniprot id: A4J2G9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

349161:DRED RS14425
gene id: 349161:DRED_RS14425
uniprot id: A4J804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.

349161:DRED RS01560
gene id: 349161:DRED_RS01560
uniprot id: A4J187
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS00720
gene id: 349161:DRED_RS00720
uniprot id: A4J0T1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

349161:DRED RS16595
gene id: 349161:DRED_RS16595
uniprot id: A4J967
names: Similarity
messages: Belongs to the HepT RNase toxin family.

349161:DRED RS11610
gene id: 349161:DRED_RS11610
uniprot id: A4J6I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS09050
gene id: 349161:DRED_RS09050
uniprot id: A4J561
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

349161:DRED RS10445
gene id: 349161:DRED_RS10445
uniprot id: A4J5X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

349161:DRED RS13290
gene id: 349161:DRED_RS13290
uniprot id: A4J7F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

349161:DRED RS00540
gene id: 349161:DRED_RS00540
uniprot id: A4J0P4
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

349161:DRED RS06300
gene id: 349161:DRED_RS06300
uniprot id: A4J3Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

349161:DRED RS03640
gene id: 349161:DRED_RS03640
uniprot id: A4J2B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

349161:DRED RS12740
gene id: 349161:DRED_RS12740
uniprot id: A4J752
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

349161:DRED RS10485
gene id: 349161:DRED_RS10485
uniprot id: A4J5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

349161:DRED RS17390
gene id: 349161:DRED_RS17390
uniprot id: A4J9M0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

349161:DRED RS09585
gene id: 349161:DRED_RS09585
uniprot id: A4J5G3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS09990
gene id: 349161:DRED_RS09990
uniprot id: A4J5N9
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

349161:DRED RS09020
gene id: 349161:DRED_RS09020
uniprot id: A4J555
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

349161:DRED RS01525
gene id: 349161:DRED_RS01525
uniprot id: A4J180
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

349161:DRED RS14560
gene id: 349161:DRED_RS14560
uniprot id: A4J830
names: Similarity
messages: Belongs to the IMPACT family.

349161:DRED RS09790
gene id: 349161:DRED_RS09790
uniprot id: A4J5K0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

349161:DRED RS16055
gene id: 349161:DRED_RS16055
uniprot id: A4J8W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS01600
gene id: 349161:DRED_RS01600
uniprot id: A4J195
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

349161:DRED RS05525
gene id: 349161:DRED_RS05525
uniprot id: A4J3A1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

349161:DRED RS12735
gene id: 349161:DRED_RS12735
uniprot id: A4J751
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

349161:DRED RS14695
gene id: 349161:DRED_RS14695
uniprot id: A4J857
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349161:DRED RS10505
gene id: 349161:DRED_RS10505
uniprot id: A4J5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

349161:DRED RS07255
gene id: 349161:DRED_RS07255
uniprot id: A4J471
names: Similarity
messages: Belongs to the UPF0251 family.

349161:DRED RS16200
gene id: 349161:DRED_RS16200
uniprot id: A4J8Z0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS17410
gene id: 349161:DRED_RS17410
uniprot id: A4J9M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

349161:DRED RS13555
gene id: 349161:DRED_RS13555
uniprot id: A4J7K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

349161:DRED RS06885
gene id: 349161:DRED_RS06885
uniprot id: A4J400
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS01470
gene id: 349161:DRED_RS01470
uniprot id: A4J169
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

349161:DRED RS03125
gene id: 349161:DRED_RS03125
uniprot id: A4J218
names: Similarity
messages: Belongs to the EamA transporter family.

349161:DRED RS01115
gene id: 349161:DRED_RS01115
uniprot id: A4J0Z8
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

349161:DRED RS12515
gene id: 349161:DRED_RS12515
uniprot id: A4J707
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

349161:DRED RS13065
gene id: 349161:DRED_RS13065
uniprot id: A4J7B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

349161:DRED RS09040
gene id: 349161:DRED_RS09040
uniprot id: A4J559
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits (By similarity). However, the metal reductase complex seems to be composed of a heterooctamer of 4 PyrK and 4 PyrD subunits (PubMed:25389064).
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
messages: Together with PyrD, also forms a metal reductase complex able to reduce Fe(III)-chelates to Fe(II)-chelates, as well as soluble Cr(VI) and U(VI), using NADH as electron donor. To a lesser extent, can also use NADPH as an electron donor. Is unable to reduce riboflavin and FMN with NADH as electron donor. May have an in vivo role in metal reduction in D.reducens, which is an organism capable of reducing contaminant heavy metals and radionuclides.

349161:DRED RS11950
gene id: 349161:DRED_RS11950
uniprot id: A4J6P9
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS14965
gene id: 349161:DRED_RS14965
uniprot id: A4J8A6
names: Similarity
messages: Belongs to the glutamate synthase family.

349161:DRED RS10050
gene id: 349161:DRED_RS10050
uniprot id: A4J5Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

349161:DRED RS00855
gene id: 349161:DRED_RS00855
uniprot id: A4J0V8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

349161:DRED RS05295
gene id: 349161:DRED_RS05295
uniprot id: A4J356
names: Similarity
messages: Belongs to the type IA topoisomerase family.

349161:DRED RS02190
gene id: 349161:DRED_RS02190
uniprot id: A4J1K3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS11195
gene id: 349161:DRED_RS11195
uniprot id: A4J6B8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

349161:DRED RS05600
gene id: 349161:DRED_RS05600
uniprot id: A4J3B6
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS08385
gene id: 349161:DRED_RS08385
uniprot id: A4J4T2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349161:DRED RS13275
gene id: 349161:DRED_RS13275
uniprot id: A4J7F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

349161:DRED RS10345
gene id: 349161:DRED_RS10345
uniprot id: A4J5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

349161:DRED RS15800
gene id: 349161:DRED_RS15800
uniprot id: A4J8R6
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

349161:DRED RS17000
gene id: 349161:DRED_RS17000
uniprot id: A4J9E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

349161:DRED RS00010
gene id: 349161:DRED_RS00010
uniprot id: A4J0F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

349161:DRED RS01235
gene id: 349161:DRED_RS01235
uniprot id: A4J122
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

349161:DRED RS05955
gene id: 349161:DRED_RS05955
uniprot id: A4J3I5
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

349161:DRED RS14280
gene id: 349161:DRED_RS14280
uniprot id: A4J7X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

349161:DRED RS10355
gene id: 349161:DRED_RS10355
uniprot id: A4J5V6
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

349161:DRED RS10155
gene id: 349161:DRED_RS10155
uniprot id: A4J5S1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS17135
gene id: 349161:DRED_RS17135
uniprot id: A4J9H2
names: Caution
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

349161:DRED RS10495
gene id: 349161:DRED_RS10495
uniprot id: A4J5Y2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS01010
gene id: 349161:DRED_RS01010
uniprot id: A4J0Y2
names: Similarity
messages: Belongs to the ycf81 family.

349161:DRED RS17145
gene id: 349161:DRED_RS17145
uniprot id: A4J9H4
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS00805
gene id: 349161:DRED_RS00805
uniprot id: A4J0U8
names: Similarity
messages: Belongs to the thioesterase PaaI family.

349161:DRED RS10140
gene id: 349161:DRED_RS10140
uniprot id: A4J5R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

349161:DRED RS14770
gene id: 349161:DRED_RS14770
uniprot id: A4J872
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

349161:DRED RS15625
gene id: 349161:DRED_RS15625
uniprot id: A4J8N3
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS14600
gene id: 349161:DRED_RS14600
uniprot id: A4J838
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349161:DRED RS12730
gene id: 349161:DRED_RS12730
uniprot id: A4J750
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

349161:DRED RS00685
gene id: 349161:DRED_RS00685
uniprot id: A4J0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

349161:DRED RS09130
gene id: 349161:DRED_RS09130
uniprot id: A4J577
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

349161:DRED RS03910
gene id: 349161:DRED_RS03910
uniprot id: A4J2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS10910
gene id: 349161:DRED_RS10910
uniprot id: A4J662
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

349161:DRED RS14920
gene id: 349161:DRED_RS14920
uniprot id: A4J898
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.

349161:DRED RS12430
gene id: 349161:DRED_RS12430
uniprot id: A4J6Z0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

349161:DRED RS00265
gene id: 349161:DRED_RS00265
uniprot id: A4J0J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

349161:DRED RS00545
gene id: 349161:DRED_RS00545
uniprot id: A4J0P5
names: Function
names: Similarity
messages: Belongs to the SpoVG family.
messages: Could be involved in septation.

349161:DRED RS14345
gene id: 349161:DRED_RS14345
uniprot id: A4J7Z1
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

349161:DRED RS09940
gene id: 349161:DRED_RS09940
uniprot id: A4J5M9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

349161:DRED RS04885
gene id: 349161:DRED_RS04885
uniprot id: A4J2Y3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

349161:DRED RS01035
gene id: 349161:DRED_RS01035
uniprot id: A4J0Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

349161:DRED RS14290
gene id: 349161:DRED_RS14290
uniprot id: A4J7Y1
names: Similarity
messages: Belongs to the terpene synthase family.

349161:DRED RS07010
gene id: 349161:DRED_RS07010
uniprot id: A4J424
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS03765
gene id: 349161:DRED_RS03765
uniprot id: A4J2D7
names: Similarity
messages: Belongs to the cytochrome c-552 family.

349161:DRED RS02140
gene id: 349161:DRED_RS02140
uniprot id: A4J1J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349161:DRED RS08540
gene id: 349161:DRED_RS08540
uniprot id: A4J4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

349161:DRED RS02095
gene id: 349161:DRED_RS02095
uniprot id: A4J1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS09070
gene id: 349161:DRED_RS09070
uniprot id: A4J565
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

349161:DRED RS16910
gene id: 349161:DRED_RS16910
uniprot id: A4J9C8
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS09105
gene id: 349161:DRED_RS09105
uniprot id: A4J572
names: Similarity
messages: Belongs to the YicC/YloC family.

349161:DRED RS05935
gene id: 349161:DRED_RS05935
uniprot id: A4J3I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

349161:DRED RS04740
gene id: 349161:DRED_RS04740
uniprot id: A4J2W2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349161:DRED RS15750
gene id: 349161:DRED_RS15750
uniprot id: A4J8Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

349161:DRED RS03260
gene id: 349161:DRED_RS03260
uniprot id: A4J238
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS08600
gene id: 349161:DRED_RS08600
uniprot id: A4J4X5
names: Similarity
messages: Belongs to the peptidase S41A family.

349161:DRED RS08020
gene id: 349161:DRED_RS08020
uniprot id: A4J4L7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349161:DRED RS13530
gene id: 349161:DRED_RS13530
uniprot id: A4J7K0
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

349161:DRED RS12120
gene id: 349161:DRED_RS12120
uniprot id: A4J6T0
names: Similarity
messages: Belongs to the AOR/FOR family.

349161:DRED RS09410
gene id: 349161:DRED_RS09410
uniprot id: A4J5D0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homomer.

349161:DRED RS19375
gene id: 349161:DRED_RS19375
uniprot id: A4J757
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

349161:DRED RS13525
gene id: 349161:DRED_RS13525
uniprot id: A4J7J9
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

349161:DRED RS04550
gene id: 349161:DRED_RS04550
uniprot id: A4J2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

349161:DRED RS07835
gene id: 349161:DRED_RS07835
uniprot id: A4J4I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

349161:DRED RS13170
gene id: 349161:DRED_RS13170
uniprot id: A4J7D0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349161:DRED RS16180
gene id: 349161:DRED_RS16180
uniprot id: A4J8Y7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

349161:DRED RS05920
gene id: 349161:DRED_RS05920
uniprot id: A4J3H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

349161:DRED RS13200
gene id: 349161:DRED_RS13200
uniprot id: A4J7D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

349161:DRED RS01485
gene id: 349161:DRED_RS01485
uniprot id: A4J172
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

349161:DRED RS00225
gene id: 349161:DRED_RS00225
uniprot id: A4J0I3
names: Subcellular Location Annotation
messages: Cytoplasm

349161:DRED RS06875
gene id: 349161:DRED_RS06875
uniprot id: A4J3Z8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS12105
gene id: 349161:DRED_RS12105
uniprot id: A4J6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS04435
gene id: 349161:DRED_RS04435
uniprot id: A4J2R0
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS15745
gene id: 349161:DRED_RS15745
uniprot id: A4J8Q5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

349161:DRED RS07220
gene id: 349161:DRED_RS07220
uniprot id: A4J464
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349161:DRED RS14110
gene id: 349161:DRED_RS14110
uniprot id: A4J7U5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS02685
gene id: 349161:DRED_RS02685
uniprot id: A4J1T6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS02130
gene id: 349161:DRED_RS02130
uniprot id: A4J1J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

349161:DRED RS07980
gene id: 349161:DRED_RS07980
uniprot id: A4J4K9
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

349161:DRED RS00975
gene id: 349161:DRED_RS00975
uniprot id: A4J0X5
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

349161:DRED RS09580
gene id: 349161:DRED_RS09580
uniprot id: A4J5G2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

349161:DRED RS11425
gene id: 349161:DRED_RS11425
uniprot id: A4J6F8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

349161:DRED RS06775
gene id: 349161:DRED_RS06775
uniprot id: A4J3Y3
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

349161:DRED RS12165
gene id: 349161:DRED_RS12165
uniprot id: A4J6T9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349161:DRED RS07195
gene id: 349161:DRED_RS07195
uniprot id: A4J459
names: Similarity
messages: Belongs to the HdrA family.

349161:DRED RS03865
gene id: 349161:DRED_RS03865
uniprot id: A4J2F5
names: Function
names: Similarity
messages: Belongs to the alpha/beta-type SASP family.
messages: SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.

349161:DRED RS09570
gene id: 349161:DRED_RS09570
uniprot id: A4J5G0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

349161:DRED RS17580
gene id: 349161:DRED_RS17580
uniprot id: A4J9Q5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

349161:DRED RS09155
gene id: 349161:DRED_RS09155
uniprot id: A4J582
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

349161:DRED RS10210
gene id: 349161:DRED_RS10210
uniprot id: A4J5T1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349161:DRED RS08840
gene id: 349161:DRED_RS08840
uniprot id: A4J522
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS05945
gene id: 349161:DRED_RS05945
uniprot id: A4J3I3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

349161:DRED RS06245
gene id: 349161:DRED_RS06245
uniprot id: A4J3P1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

349161:DRED RS15930
gene id: 349161:DRED_RS15930
uniprot id: A4J8T8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

349161:DRED RS06925
gene id: 349161:DRED_RS06925
uniprot id: A4J409
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

349161:DRED RS12585
gene id: 349161:DRED_RS12585
uniprot id: A4J721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

349161:DRED RS17655
gene id: 349161:DRED_RS17655
uniprot id: A4J9S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

349161:DRED RS08375
gene id: 349161:DRED_RS08375
uniprot id: A4J4T0
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS08955
gene id: 349161:DRED_RS08955
uniprot id: A4J544
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

349161:DRED RS10170
gene id: 349161:DRED_RS10170
uniprot id: A4J5S4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

349161:DRED RS11260
gene id: 349161:DRED_RS11260
uniprot id: A4J6D1
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS12090
gene id: 349161:DRED_RS12090
uniprot id: A4J6S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

349161:DRED RS16570
gene id: 349161:DRED_RS16570
uniprot id: A4J962
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

349161:DRED RS10615
gene id: 349161:DRED_RS10615
uniprot id: A4J605
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

349161:DRED RS11510
gene id: 349161:DRED_RS11510
uniprot id: A4J6G9
names: Similarity
messages: Belongs to the UPF0145 family.

349161:DRED RS05460
gene id: 349161:DRED_RS05460
uniprot id: A4J388
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

349161:DRED RS03005
gene id: 349161:DRED_RS03005
uniprot id: A4J1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS05185
gene id: 349161:DRED_RS05185
uniprot id: A4J336
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS07435
gene id: 349161:DRED_RS07435
uniprot id: A4J4A0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS01145
gene id: 349161:DRED_RS01145
uniprot id: A4J104
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

349161:DRED RS17800
gene id: 349161:DRED_RS17800
uniprot id: A4J333
names: Similarity
messages: Belongs to the peptidase A24 family.

349161:DRED RS01865
gene id: 349161:DRED_RS01865
uniprot id: A4J1E6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

349161:DRED RS15160
gene id: 349161:DRED_RS15160
uniprot id: A4J8E5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Composed of a catalytic GlpA/B dimer and of membrane bound GlpC.
messages: Membrane

349161:DRED RS14465
gene id: 349161:DRED_RS14465
uniprot id: A4J812
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

349161:DRED RS06120
gene id: 349161:DRED_RS06120
uniprot id: A4J3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpB family.
messages: Cytoplasm
messages: Homodimer. Homodimerization may be required to stabilize the binding of ScpA to the Smc head domains. Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.

349161:DRED RS16385
gene id: 349161:DRED_RS16385
uniprot id: A4J925
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS12725
gene id: 349161:DRED_RS12725
uniprot id: A4J749
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

349161:DRED RS15940
gene id: 349161:DRED_RS15940
uniprot id: A4J8U0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349161:DRED RS05990
gene id: 349161:DRED_RS05990
uniprot id: A4J3J2
names: Similarity
messages: Belongs to the GerABKA family.

349161:DRED RS10975
gene id: 349161:DRED_RS10975
uniprot id: A4J675
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

349161:DRED RS12855
gene id: 349161:DRED_RS12855
uniprot id: A4J775
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

349161:DRED RS09955
gene id: 349161:DRED_RS09955
uniprot id: A4J5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

349161:DRED RS00900
gene id: 349161:DRED_RS00900
uniprot id: A4J0W7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS16765
gene id: 349161:DRED_RS16765
uniprot id: A4J9A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

349161:DRED RS01325
gene id: 349161:DRED_RS01325
uniprot id: A4J140
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

349161:DRED RS13475
gene id: 349161:DRED_RS13475
uniprot id: A4J7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS02460
gene id: 349161:DRED_RS02460
uniprot id: A4J1Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

349161:DRED RS02610
gene id: 349161:DRED_RS02610
uniprot id: A4J1T1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

349161:DRED RS08960
gene id: 349161:DRED_RS08960
uniprot id: A4J545
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

349161:DRED RS11785
gene id: 349161:DRED_RS11785
uniprot id: A4J6L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

349161:DRED RS12330
gene id: 349161:DRED_RS12330
uniprot id: A4J6X0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS17490
gene id: 349161:DRED_RS17490
uniprot id: A4J9P1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS00340
gene id: 349161:DRED_RS00340
uniprot id: A4J0K5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

349161:DRED RS04910
gene id: 349161:DRED_RS04910
uniprot id: A4J2Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

349161:DRED RS16755
gene id: 349161:DRED_RS16755
uniprot id: A4J999
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

349161:DRED RS15935
gene id: 349161:DRED_RS15935
uniprot id: A4J8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

349161:DRED RS16405
gene id: 349161:DRED_RS16405
uniprot id: A4J929
names: Subcellular Location Annotation
messages: Cytoplasm

349161:DRED RS00695
gene id: 349161:DRED_RS00695
uniprot id: A4J0S6
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

349161:DRED RS00095
gene id: 349161:DRED_RS00095
uniprot id: A4J0G4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

349161:DRED RS08995
gene id: 349161:DRED_RS08995
uniprot id: A4J550
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane

349161:DRED RS14575
gene id: 349161:DRED_RS14575
uniprot id: A4J833
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

349161:DRED RS10920
gene id: 349161:DRED_RS10920
uniprot id: A4J664
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

349161:DRED RS06320
gene id: 349161:DRED_RS06320
uniprot id: A4J3Q5
names: Function
names: Similarity
messages: Belongs to the BshC family.
messages: Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.

349161:DRED RS10285
gene id: 349161:DRED_RS10285
uniprot id: A4J5U6
names: Similarity
messages: Belongs to the DprA/Smf family.

349161:DRED RS06280
gene id: 349161:DRED_RS06280
uniprot id: A4J3P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

349161:DRED RS11120
gene id: 349161:DRED_RS11120
uniprot id: A4J6A4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

349161:DRED RS11715
gene id: 349161:DRED_RS11715
uniprot id: A4J6K4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

349161:DRED RS11215
gene id: 349161:DRED_RS11215
uniprot id: A4J6C2
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS13255
gene id: 349161:DRED_RS13255
uniprot id: A4J7E7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

349161:DRED RS05530
gene id: 349161:DRED_RS05530
uniprot id: A4J3A2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

349161:DRED RS14350
gene id: 349161:DRED_RS14350
uniprot id: A4J7Z2
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

349161:DRED RS01480
gene id: 349161:DRED_RS01480
uniprot id: A4J171
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS03845
gene id: 349161:DRED_RS03845
uniprot id: A4J2F2
names: Subcellular Location Annotation
messages: Cytoplasm

349161:DRED RS07275
gene id: 349161:DRED_RS07275
uniprot id: A4J474
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

349161:DRED RS08475
gene id: 349161:DRED_RS08475
uniprot id: A4J4V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS13080
gene id: 349161:DRED_RS13080
uniprot id: A4J7B6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

349161:DRED RS15045
gene id: 349161:DRED_RS15045
uniprot id: A4J8C2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity.

349161:DRED RS14040
gene id: 349161:DRED_RS14040
uniprot id: A4J7T2
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS01360
gene id: 349161:DRED_RS01360
uniprot id: A4J147
names: Similarity
messages: Belongs to the TrpC family.

349161:DRED RS08275
gene id: 349161:DRED_RS08275
uniprot id: A4J4R1
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS16915
gene id: 349161:DRED_RS16915
uniprot id: A4J9C9
names: Similarity
messages: Belongs to the peptidase S49 family.

349161:DRED RS05260
gene id: 349161:DRED_RS05260
uniprot id: A4J349
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS10850
gene id: 349161:DRED_RS10850
uniprot id: A4J650
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS16810
gene id: 349161:DRED_RS16810
uniprot id: A4J9B0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

349161:DRED RS16330
gene id: 349161:DRED_RS16330
uniprot id: A4J916
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

349161:DRED RS04155
gene id: 349161:DRED_RS04155
uniprot id: A4J2L3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

349161:DRED RS09805
gene id: 349161:DRED_RS09805
uniprot id: A4J5K3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

349161:DRED RS17400
gene id: 349161:DRED_RS17400
uniprot id: A4J9M2
names: Similarity
messages: Belongs to the EutP/PduV family.

349161:DRED RS00860
gene id: 349161:DRED_RS00860
uniprot id: A4J0V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

349161:DRED RS10750
gene id: 349161:DRED_RS10750
uniprot id: A4J631
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

349161:DRED RS09625
gene id: 349161:DRED_RS09625
uniprot id: A4J5G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

349161:DRED RS13125
gene id: 349161:DRED_RS13125
uniprot id: A4J7C1
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

349161:DRED RS13385
gene id: 349161:DRED_RS13385
uniprot id: A4J7H3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

349161:DRED RS01040
gene id: 349161:DRED_RS01040
uniprot id: A4J0Y8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

349161:DRED RS13295
gene id: 349161:DRED_RS13295
uniprot id: A4J7F5
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

349161:DRED RS14215
gene id: 349161:DRED_RS14215
uniprot id: A4J7W6
names: Similarity
messages: Belongs to the GerABKA family.

349161:DRED RS03625
gene id: 349161:DRED_RS03625
uniprot id: A4J2B0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS00965
gene id: 349161:DRED_RS00965
uniprot id: A4J0X3
names: Similarity
messages: Belongs to the CtsR family.

349161:DRED RS10900
gene id: 349161:DRED_RS10900
uniprot id: A4J660
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS08480
gene id: 349161:DRED_RS08480
uniprot id: A4J4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS12325
gene id: 349161:DRED_RS12325
uniprot id: A4J6W9
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

349161:DRED RS05665
gene id: 349161:DRED_RS05665
uniprot id: A4J3C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

349161:DRED RS13370
gene id: 349161:DRED_RS13370
uniprot id: A4J7H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS10885
gene id: 349161:DRED_RS10885
uniprot id: A4J657
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS13015
gene id: 349161:DRED_RS13015
uniprot id: A4J7A4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

349161:DRED RS04120
gene id: 349161:DRED_RS04120
uniprot id: A4J2K6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

349161:DRED RS00990
gene id: 349161:DRED_RS00990
uniprot id: A4J0X8
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

349161:DRED RS06900
gene id: 349161:DRED_RS06900
uniprot id: A4J403
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS09995
gene id: 349161:DRED_RS09995
uniprot id: A4J5P0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

349161:DRED RS00765
gene id: 349161:DRED_RS00765
uniprot id: A4J0T9
names: Similarity
messages: Belongs to the HdrA family.

349161:DRED RS12640
gene id: 349161:DRED_RS12640
uniprot id: A4J732
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

349161:DRED RS09810
gene id: 349161:DRED_RS09810
uniprot id: A4J5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

349161:DRED RS13735
gene id: 349161:DRED_RS13735
uniprot id: A4J7N4
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

349161:DRED RS11125
gene id: 349161:DRED_RS11125
uniprot id: A4J6A5
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

349161:DRED RS07460
gene id: 349161:DRED_RS07460
uniprot id: A4J4A5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

349161:DRED RS17045
gene id: 349161:DRED_RS17045
uniprot id: A4J9F5
names: Similarity
messages: Belongs to the UPF0045 family.

349161:DRED RS14660
gene id: 349161:DRED_RS14660
uniprot id: A4J187
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS01105
gene id: 349161:DRED_RS01105
uniprot id: A4J0Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

349161:DRED RS06430
gene id: 349161:DRED_RS06430
uniprot id: A4J3S4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

349161:DRED RS10880
gene id: 349161:DRED_RS10880
uniprot id: A4J656
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

349161:DRED RS06990
gene id: 349161:DRED_RS06990
uniprot id: A4J420
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS15245
gene id: 349161:DRED_RS15245
uniprot id: A4J8G2
names: Similarity
messages: Belongs to the P(II) protein family.

349161:DRED RS05540
gene id: 349161:DRED_RS05540
uniprot id: A4J3A4
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS11015
gene id: 349161:DRED_RS11015
uniprot id: A4J683
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

349161:DRED RS11025
gene id: 349161:DRED_RS11025
uniprot id: A4J685
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

349161:DRED RS03370
gene id: 349161:DRED_RS03370
uniprot id: A4J260
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS10995
gene id: 349161:DRED_RS10995
uniprot id: A4J679
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

349161:DRED RS01195
gene id: 349161:DRED_RS01195
uniprot id: A4J114
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

349161:DRED RS09005
gene id: 349161:DRED_RS09005
uniprot id: A4J552
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Cell membrane
messages: Membrane

349161:DRED RS12420
gene id: 349161:DRED_RS12420
uniprot id: A4J6Y8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

349161:DRED RS07155
gene id: 349161:DRED_RS07155
uniprot id: A4J451
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

349161:DRED RS13430
gene id: 349161:DRED_RS13430
uniprot id: A4J7I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

349161:DRED RS13670
gene id: 349161:DRED_RS13670
uniprot id: A4J7M2
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS17510
gene id: 349161:DRED_RS17510
uniprot id: A4J9P5
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

349161:DRED RS13330
gene id: 349161:DRED_RS13330
uniprot id: A4J7G2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

349161:DRED RS11945
gene id: 349161:DRED_RS11945
uniprot id: A4J6P8
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS14315
gene id: 349161:DRED_RS14315
uniprot id: A4J7Y5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

349161:DRED RS11600
gene id: 349161:DRED_RS11600
uniprot id: A4J6I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

349161:DRED RS16020
gene id: 349161:DRED_RS16020
uniprot id: A4J8V6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

349161:DRED RS14320
gene id: 349161:DRED_RS14320
uniprot id: A4J7Y6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

349161:DRED RS03860
gene id: 349161:DRED_RS03860
uniprot id: A4J2F4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

349161:DRED RS15420
gene id: 349161:DRED_RS15420
uniprot id: A4J8J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

349161:DRED RS01550
gene id: 349161:DRED_RS01550
uniprot id: A4J185
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

349161:DRED RS03740
gene id: 349161:DRED_RS03740
uniprot id: A4J2D2
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS13520
gene id: 349161:DRED_RS13520
uniprot id: A4J7J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

349161:DRED RS15320
gene id: 349161:DRED_RS15320
uniprot id: A4J8H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

349161:DRED RS05940
gene id: 349161:DRED_RS05940
uniprot id: A4J3I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

349161:DRED RS00235
gene id: 349161:DRED_RS00235
uniprot id: A4J0I5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

349161:DRED RS15610
gene id: 349161:DRED_RS15610
uniprot id: A4J8N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

349161:DRED RS06910
gene id: 349161:DRED_RS06910
uniprot id: A4J405
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

349161:DRED RS02060
gene id: 349161:DRED_RS02060
uniprot id: A4J1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

349161:DRED RS16855
gene id: 349161:DRED_RS16855
uniprot id: A4J9B9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

349161:DRED RS02180
gene id: 349161:DRED_RS02180
uniprot id: A4J1K1
names: Similarity
messages: Belongs to the ACC deaminase/D-cysteine desulfhydrase family.

349161:DRED RS06170
gene id: 349161:DRED_RS06170
uniprot id: A4J3M6
names: Function
names: Similarity
names: Subunit
messages: Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
messages: Belongs to the HutP family.
messages: Homohexamer.

349161:DRED RS03800
gene id: 349161:DRED_RS03800
uniprot id: A4J2E3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS02330
gene id: 349161:DRED_RS02330
uniprot id: A4J1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS08935
gene id: 349161:DRED_RS08935
uniprot id: A4J540
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

349161:DRED RS15410
gene id: 349161:DRED_RS15410
uniprot id: A4J8J5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

349161:DRED RS08700
gene id: 349161:DRED_RS08700
uniprot id: A4J4Z4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

349161:DRED RS04655
gene id: 349161:DRED_RS04655
uniprot id: A4J2U7
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS09115
gene id: 349161:DRED_RS09115
uniprot id: A4J574
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

349161:DRED RS09205
gene id: 349161:DRED_RS09205
uniprot id: A4J592
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS03980
gene id: 349161:DRED_RS03980
uniprot id: A4J2H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS17345
gene id: 349161:DRED_RS17345
uniprot id: A4J9L1
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

349161:DRED RS13215
gene id: 349161:DRED_RS13215
uniprot id: A4J7D9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

349161:DRED RS03685
gene id: 349161:DRED_RS03685
uniprot id: A4J2C2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

349161:DRED RS15315
gene id: 349161:DRED_RS15315
uniprot id: A4J8H6
names: Function
messages: May be involved in the biosynthesis of molybdopterin.

349161:DRED RS05590
gene id: 349161:DRED_RS05590
uniprot id: A4J3B4
names: Similarity
messages: Belongs to the peptidase U62 family.

349161:DRED RS06370
gene id: 349161:DRED_RS06370
uniprot id: A4J3R4
names: Similarity
messages: Belongs to the peptidase S24 family.

349161:DRED RS10555
gene id: 349161:DRED_RS10555
uniprot id: A4J5Z3
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

349161:DRED RS11565
gene id: 349161:DRED_RS11565
uniprot id: A4J6I0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

349161:DRED RS01285
gene id: 349161:DRED_RS01285
uniprot id: A4J132
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

349161:DRED RS08420
gene id: 349161:DRED_RS08420
uniprot id: A4J4T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS09875
gene id: 349161:DRED_RS09875
uniprot id: A4J5L7
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS12600
gene id: 349161:DRED_RS12600
uniprot id: A4J724
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

349161:DRED RS00415
gene id: 349161:DRED_RS00415
uniprot id: A4J0M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

349161:DRED RS02395
gene id: 349161:DRED_RS02395
uniprot id: A4J1P4
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS08025
gene id: 349161:DRED_RS08025
uniprot id: A4J4L8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349161:DRED RS14820
gene id: 349161:DRED_RS14820
uniprot id: A4J882
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

349161:DRED RS10375
gene id: 349161:DRED_RS10375
uniprot id: A4J5W0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

349161:DRED RS03305
gene id: 349161:DRED_RS03305
uniprot id: A4J246
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

349161:DRED RS08965
gene id: 349161:DRED_RS08965
uniprot id: A4J546
names: Similarity
messages: Belongs to the UPF0237 family.

349161:DRED RS08300
gene id: 349161:DRED_RS08300
uniprot id: A4J4R5
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

349161:DRED RS03890
gene id: 349161:DRED_RS03890
uniprot id: A4J2G0
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS00555
gene id: 349161:DRED_RS00555
uniprot id: A4J0P7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

349161:DRED RS09110
gene id: 349161:DRED_RS09110
uniprot id: A4J573
names: Similarity
messages: Belongs to the RemA family.

349161:DRED RS12370
gene id: 349161:DRED_RS12370
uniprot id: A4J6X8
names: Similarity
messages: Belongs to the peptidase C40 family.

349161:DRED RS03020
gene id: 349161:DRED_RS03020
uniprot id: A4J1Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS02615
gene id: 349161:DRED_RS02615
uniprot id: A4J1T2
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

349161:DRED RS01870
gene id: 349161:DRED_RS01870
uniprot id: A4J1E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

349161:DRED RS01460
gene id: 349161:DRED_RS01460
uniprot id: A4J167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

349161:DRED RS11840
gene id: 349161:DRED_RS11840
uniprot id: A4J6M8
names: Similarity
messages: Belongs to the UPF0251 family.

349161:DRED RS00590
gene id: 349161:DRED_RS00590
uniprot id: A4J0Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

349161:DRED RS01210
gene id: 349161:DRED_RS01210
uniprot id: A4J117
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

349161:DRED RS09030
gene id: 349161:DRED_RS09030
uniprot id: A4J557
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

349161:DRED RS00525
gene id: 349161:DRED_RS00525
uniprot id: A4J0P1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

349161:DRED RS19610
gene id: 349161:DRED_RS19610
uniprot id: A4J790
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

349161:DRED RS08630
gene id: 349161:DRED_RS08630
uniprot id: A4J4Y1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

349161:DRED RS10550
gene id: 349161:DRED_RS10550
uniprot id: A4J5Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

349161:DRED RS01425
gene id: 349161:DRED_RS01425
uniprot id: A4J160
names: Similarity
messages: Belongs to the RutC family.

349161:DRED RS09280
gene id: 349161:DRED_RS09280
uniprot id: A4J5A5
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

349161:DRED RS06115
gene id: 349161:DRED_RS06115
uniprot id: A4J3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

349161:DRED RS02895
gene id: 349161:DRED_RS02895
uniprot id: A4J1X6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

349161:DRED RS10845
gene id: 349161:DRED_RS10845
uniprot id: A4J649
names: Similarity
messages: Belongs to the UPF0102 family.

349161:DRED RS10865
gene id: 349161:DRED_RS10865
uniprot id: A4J653
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

349161:DRED RS06780
gene id: 349161:DRED_RS06780
uniprot id: A4J3Y4
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

349161:DRED RS10915
gene id: 349161:DRED_RS10915
uniprot id: A4J663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

349161:DRED RS12960
gene id: 349161:DRED_RS12960
uniprot id: A4J793
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

349161:DRED RS15030
gene id: 349161:DRED_RS15030
uniprot id: A4J8B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

349161:DRED RS08915
gene id: 349161:DRED_RS08915
uniprot id: A4J536
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

349161:DRED RS16230
gene id: 349161:DRED_RS16230
uniprot id: A4J8Z7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

349161:DRED RS03730
gene id: 349161:DRED_RS03730
uniprot id: A4J2D0
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

349161:DRED RS12675
gene id: 349161:DRED_RS12675
uniprot id: A4J739
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS10280
gene id: 349161:DRED_RS10280
uniprot id: A4J5U5
names: Similarity
messages: Belongs to the UPF0234 family.

349161:DRED RS06290
gene id: 349161:DRED_RS06290
uniprot id: A4J3P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

349161:DRED RS07020
gene id: 349161:DRED_RS07020
uniprot id: A4J426
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial microcompartment
messages: Belongs to the EutB family.
messages: Binds between the large and small subunits.
messages: Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
messages: The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.

349161:DRED RS08270
gene id: 349161:DRED_RS08270
uniprot id: A4J4R0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349161:DRED RS03405
gene id: 349161:DRED_RS03405
uniprot id: A4J267
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS13565
gene id: 349161:DRED_RS13565
uniprot id: A4J7K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

349161:DRED RS10545
gene id: 349161:DRED_RS10545
uniprot id: A4J5Z1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

349161:DRED RS11615
gene id: 349161:DRED_RS11615
uniprot id: A4J6I8
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS07115
gene id: 349161:DRED_RS07115
uniprot id: A4J444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

349161:DRED RS08940
gene id: 349161:DRED_RS08940
uniprot id: A4J541
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

349161:DRED RS02930
gene id: 349161:DRED_RS02930
uniprot id: A4J1Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

349161:DRED RS11060
gene id: 349161:DRED_RS11060
uniprot id: A4J692
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

349161:DRED RS07870
gene id: 349161:DRED_RS07870
uniprot id: A4J4I7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS14265
gene id: 349161:DRED_RS14265
uniprot id: A4J7X6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

349161:DRED RS01270
gene id: 349161:DRED_RS01270
uniprot id: A4J129
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

349161:DRED RS16685
gene id: 349161:DRED_RS16685
uniprot id: A4J985
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

349161:DRED RS13575
gene id: 349161:DRED_RS13575
uniprot id: A4J7K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

349161:DRED RS02530
gene id: 349161:DRED_RS02530
uniprot id: A4J1R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS13000
gene id: 349161:DRED_RS13000
uniprot id: A4J7A1
names: Similarity
messages: Belongs to the ComB family.

349161:DRED RS08250
gene id: 349161:DRED_RS08250
uniprot id: A4J4Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS12500
gene id: 349161:DRED_RS12500
uniprot id: A4J704
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Amj family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.

349161:DRED RS12545
gene id: 349161:DRED_RS12545
uniprot id: A4J713
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

349161:DRED RS00070
gene id: 349161:DRED_RS00070
uniprot id: A4J0F9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

349161:DRED RS11685
gene id: 349161:DRED_RS11685
uniprot id: A4J6J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

349161:DRED RS13590
gene id: 349161:DRED_RS13590
uniprot id: A4J7L1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

349161:DRED RS04080
gene id: 349161:DRED_RS04080
uniprot id: A4J2J7
names: Similarity
messages: Belongs to the thioredoxin family.

349161:DRED RS16520
gene id: 349161:DRED_RS16520
uniprot id: A4J952
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

349161:DRED RS12605
gene id: 349161:DRED_RS12605
uniprot id: A4J725
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

349161:DRED RS11520
gene id: 349161:DRED_RS11520
uniprot id: A4J6H1
names: Similarity
messages: Belongs to the Ahb/Nir family.

349161:DRED RS14745
gene id: 349161:DRED_RS14745
uniprot id: A4J867
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS00735
gene id: 349161:DRED_RS00735
uniprot id: A4J0T4
names: Similarity
messages: Belongs to the HdrA family.

349161:DRED RS01320
gene id: 349161:DRED_RS01320
uniprot id: A4J139
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

349161:DRED RS04710
gene id: 349161:DRED_RS04710
uniprot id: A4J2V6
names: Similarity
messages: Belongs to the transposase 11 family.

349161:DRED RS16175
gene id: 349161:DRED_RS16175
uniprot id: A4J8Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

349161:DRED RS07390
gene id: 349161:DRED_RS07390
uniprot id: A4J493
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

349161:DRED RS08030
gene id: 349161:DRED_RS08030
uniprot id: A4J4L9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

349161:DRED RS07455
gene id: 349161:DRED_RS07455
uniprot id: A4J4A4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

349161:DRED RS01545
gene id: 349161:DRED_RS01545
uniprot id: A4J184
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

349161:DRED RS17290
gene id: 349161:DRED_RS17290
uniprot id: A4J9K1
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

349161:DRED RS00725
gene id: 349161:DRED_RS00725
uniprot id: A4J0T2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

349161:DRED RS15715
gene id: 349161:DRED_RS15715
uniprot id: A4J8P9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349161:DRED RS06255
gene id: 349161:DRED_RS06255
uniprot id: A4J3P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

349161:DRED RS08290
gene id: 349161:DRED_RS08290
uniprot id: A4J4R3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

349161:DRED RS17065
gene id: 349161:DRED_RS17065
uniprot id: A4J9F8
names: Similarity
messages: Belongs to the ABC transporter superfamily.

349161:DRED RS06350
gene id: 349161:DRED_RS06350
uniprot id: A4J3R1
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

349161:DRED RS09335
gene id: 349161:DRED_RS09335
uniprot id: A4J5B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

349161:DRED RS15920
gene id: 349161:DRED_RS15920
uniprot id: A4J8T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

349161:DRED RS15000
gene id: 349161:DRED_RS15000
uniprot id: A4J8B3
names: Similarity
messages: Belongs to the asparagine synthetase family.

349161:DRED RS00785
gene id: 349161:DRED_RS00785
uniprot id: A4J0T7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

349161:DRED RS05960
gene id: 349161:DRED_RS05960
uniprot id: A4J3I6
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

349161:DRED RS04295
gene id: 349161:DRED_RS04295
uniprot id: A4J2N8
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS16305
gene id: 349161:DRED_RS16305
uniprot id: A4J911
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS16000
gene id: 349161:DRED_RS16000
uniprot id: A4J8V2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

349161:DRED RS07190
gene id: 349161:DRED_RS07190
uniprot id: A4J458
names: Similarity
messages: Belongs to the HdrA family.

349161:DRED RS08970
gene id: 349161:DRED_RS08970
uniprot id: A4J547
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

349161:DRED RS08945
gene id: 349161:DRED_RS08945
uniprot id: A4J542
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

349161:DRED RS01185
gene id: 349161:DRED_RS01185
uniprot id: A4J112
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

349161:DRED RS02915
gene id: 349161:DRED_RS02915
uniprot id: A4J1Y0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

349161:DRED RS08780
gene id: 349161:DRED_RS08780
uniprot id: A4J510
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

349161:DRED RS13285
gene id: 349161:DRED_RS13285
uniprot id: A4J7F3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

349161:DRED RS04170
gene id: 349161:DRED_RS04170
uniprot id: A4J2L6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

349161:DRED RS11535
gene id: 349161:DRED_RS11535
uniprot id: A4J6H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

349161:DRED RS14120
gene id: 349161:DRED_RS14120
uniprot id: A4J7U7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

349161:DRED RS06020
gene id: 349161:DRED_RS06020
uniprot id: A4J3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

349161:DRED RS03815
gene id: 349161:DRED_RS03815
uniprot id: A4J2E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

349161:DRED RS15740
gene id: 349161:DRED_RS15740
uniprot id: A4J8Q4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

349161:DRED RS10440
gene id: 349161:DRED_RS10440
uniprot id: A4J5X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

349161:DRED RS08370
gene id: 349161:DRED_RS08370
uniprot id: A4J4S9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS13310
gene id: 349161:DRED_RS13310
uniprot id: A4J7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

349161:DRED RS13920
gene id: 349161:DRED_RS13920
uniprot id: A4J7R2
names: Similarity
messages: Belongs to the peptidase S14 family.

349161:DRED RS15945
gene id: 349161:DRED_RS15945
uniprot id: A4J8U1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

349161:DRED RS04180
gene id: 349161:DRED_RS04180
uniprot id: A4J2L8
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

349161:DRED RS17060
gene id: 349161:DRED_RS17060
uniprot id: A4J9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS02050
gene id: 349161:DRED_RS02050
uniprot id: A4J1H7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

349161:DRED RS05025
gene id: 349161:DRED_RS05025
uniprot id: A4J307
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

349161:DRED RS05130
gene id: 349161:DRED_RS05130
uniprot id: A4J326
names: Similarity
messages: Belongs to the GSP E family.

349161:DRED RS02045
gene id: 349161:DRED_RS02045
uniprot id: A4J1H6
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

349161:DRED RS02195
gene id: 349161:DRED_RS02195
uniprot id: A4J1K4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

349161:DRED RS10905
gene id: 349161:DRED_RS10905
uniprot id: A4J661
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

349161:DRED RS03595
gene id: 349161:DRED_RS03595
uniprot id: A4J2A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsL family.
messages: Cell membrane
messages: Essential cell division protein.
messages: Membrane

349161:DRED RS02240
gene id: 349161:DRED_RS02240
uniprot id: A4J1L4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

349161:DRED RS05445
gene id: 349161:DRED_RS05445
uniprot id: A4J385
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

349161:DRED RS06070
gene id: 349161:DRED_RS06070
uniprot id: A4J3K8
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

349161:DRED RS06030
gene id: 349161:DRED_RS06030
uniprot id: A4J3K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

349161:DRED RS17070
gene id: 349161:DRED_RS17070
uniprot id: A4J9F9
names: Similarity
messages: Belongs to the GbsR family.

349161:DRED RS01850
gene id: 349161:DRED_RS01850
uniprot id: A4J1E3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

349161:DRED RS10700
gene id: 349161:DRED_RS10700
uniprot id: A4J622
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

349161:DRED RS12590
gene id: 349161:DRED_RS12590
uniprot id: A4J722
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

349161:DRED RS07350
gene id: 349161:DRED_RS07350
uniprot id: A4J488
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS17555
gene id: 349161:DRED_RS17555
uniprot id: A4J9Q0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

349161:DRED RS05765
gene id: 349161:DRED_RS05765
uniprot id: A4J3E9
names: Similarity
messages: Belongs to the asp23 family.

349161:DRED RS01250
gene id: 349161:DRED_RS01250
uniprot id: A4J125
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

349161:DRED RS13665
gene id: 349161:DRED_RS13665
uniprot id: A4J7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

349161:DRED RS14985
gene id: 349161:DRED_RS14985
uniprot id: A4J8B0
names: Similarity
messages: Belongs to the glutamate synthase family.

349161:DRED RS15255
gene id: 349161:DRED_RS15255
uniprot id: A4J8G4
names: Similarity
messages: Belongs to the P(II) protein family.

349161:DRED RS12820
gene id: 349161:DRED_RS12820
uniprot id: A4J768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

349161:DRED RS03560
gene id: 349161:DRED_RS03560
uniprot id: A4J297
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

349161:DRED RS00595
gene id: 349161:DRED_RS00595
uniprot id: A4J0Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

349161:DRED RS03925
gene id: 349161:DRED_RS03925
uniprot id: A4J2G7
names: Similarity
messages: Belongs to the RecJ family.

349161:DRED RS09025
gene id: 349161:DRED_RS09025
uniprot id: A4J556
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

349161:DRED RS16510
gene id: 349161:DRED_RS16510
uniprot id: A4J950
names: Similarity
messages: Belongs to the UDPGP type 2 family.

349161:DRED RS04895
gene id: 349161:DRED_RS04895
uniprot id: A4J2Y5
names: Similarity
messages: Belongs to the transpeptidase family.

349161:DRED RS17920
gene id: 349161:DRED_RS17920
uniprot id: A4J4T1
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

349161:DRED RS09135
gene id: 349161:DRED_RS09135
uniprot id: A4J578
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

349161:DRED RS09690
gene id: 349161:DRED_RS09690
uniprot id: A4J5I2
names: Similarity
messages: Belongs to the hexokinase family.

349161:DRED RS05835
gene id: 349161:DRED_RS05835
uniprot id: A4J3G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

349161:DRED RS12350
gene id: 349161:DRED_RS12350
uniprot id: A4J6X4
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

349161:DRED RS08050
gene id: 349161:DRED_RS08050
uniprot id: A4J4M2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

349161:DRED RS12645
gene id: 349161:DRED_RS12645
uniprot id: A4J733
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

349161:DRED RS10560
gene id: 349161:DRED_RS10560
uniprot id: A4J5Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

349161:DRED RS00315
gene id: 349161:DRED_RS00315
uniprot id: A4J0K0
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

349161:DRED RS10605
gene id: 349161:DRED_RS10605
uniprot id: A4J603
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

349161:DRED RS03450
gene id: 349161:DRED_RS03450
uniprot id: A4J276
names: Similarity
messages: Belongs to the HdrA family.

349161:DRED RS12925
gene id: 349161:DRED_RS12925
uniprot id: A4J787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

349161:DRED RS03620
gene id: 349161:DRED_RS03620
uniprot id: A4J2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

349161:DRED RS08870
gene id: 349161:DRED_RS08870
uniprot id: A4J528
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

349161:DRED RS07790
gene id: 349161:DRED_RS07790
uniprot id: A4J4H1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

349161:DRED RS15525
gene id: 349161:DRED_RS15525
uniprot id: A4J8L9
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

349161:DRED RS17545
gene id: 349161:DRED_RS17545
uniprot id: A4J9P8
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

349161:DRED RS12095
gene id: 349161:DRED_RS12095
uniprot id: A4J6S5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

349161:DRED RS17175
gene id: 349161:DRED_RS17175
uniprot id: A4J9I0
names: Similarity
messages: Belongs to the OsmC/Ohr family.

349161:DRED RS11045
gene id: 349161:DRED_RS11045
uniprot id: A4J689
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

349161:DRED RS08575
gene id: 349161:DRED_RS08575
uniprot id: A4J4X0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

349161:DRED RS05610
gene id: 349161:DRED_RS05610
uniprot id: A4J3B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

349161:DRED RS09015
gene id: 349161:DRED_RS09015
uniprot id: A4J554
names: Function
names: Similarity
names: Subunit
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Homodimer and homohexamer; in equilibrium.
messages: Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes.

349161:DRED RS03600
gene id: 349161:DRED_RS03600
uniprot id: A4J2A5
names: Similarity
messages: Belongs to the transpeptidase family.

349161:DRED RS08975
gene id: 349161:DRED_RS08975
uniprot id: A4J548
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

349161:DRED RS17550
gene id: 349161:DRED_RS17550
uniprot id: A4J9P9
names: Similarity
messages: Belongs to the peptidase S16 family.

349161:DRED RS16485
gene id: 349161:DRED_RS16485
uniprot id: A4J945
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

349161:DRED RS01565
gene id: 349161:DRED_RS01565
uniprot id: A4J188
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

349161:DRED RS16970
gene id: 349161:DRED_RS16970
uniprot id: A4J9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

349161:DRED RS13305
gene id: 349161:DRED_RS13305
uniprot id: A4J7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

349161:DRED RS17150
gene id: 349161:DRED_RS17150
uniprot id: A4J9H5
names: Subcellular Location Annotation
messages: Membrane

349161:DRED RS04145
gene id: 349161:DRED_RS04145
uniprot id: A4J2L1
names: Similarity
messages: Belongs to the UPF0473 family.

349161:DRED RS00085
gene id: 349161:DRED_RS00085
uniprot id: A4J0G2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

349161:DRED RS12595
gene id: 349161:DRED_RS12595
uniprot id: A4J723
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

349161:DRED RS15380
gene id: 349161:DRED_RS15380
uniprot id: A4J8I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

349161:DRED RS08555
gene id: 349161:DRED_RS08555
uniprot id: A4J4W7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

349161:DRED RS00005
gene id: 349161:DRED_RS00005
uniprot id: A4J0F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

349161:DRED RS16835
gene id: 349161:DRED_RS16835
uniprot id: A4J9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

349161:DRED RS03960
gene id: 349161:DRED_RS03960
uniprot id: A4J2H4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

349161:DRED RS01230
gene id: 349161:DRED_RS01230
uniprot id: A4J121
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

349161:DRED RS03795
gene id: 349161:DRED_RS03795
uniprot id: A4J2E2
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

349161:DRED RS05780
gene id: 349161:DRED_RS05780
uniprot id: A4J3F2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

349161:DRED RS10015
gene id: 349161:DRED_RS10015
uniprot id: A4J5P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

349161:DRED RS09080
gene id: 349161:DRED_RS09080
uniprot id: A4J567
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

349161:DRED RS07450
gene id: 349161:DRED_RS07450
uniprot id: A4J4A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

349161:DRED RS11795
gene id: 349161:DRED_RS11795
uniprot id: A4J6L9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

349161:DRED RS01310
gene id: 349161:DRED_RS01310
uniprot id: A4J137
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

349161:DRED RS09275
gene id: 349161:DRED_RS09275
uniprot id: A4J5A4
names: Similarity
messages: Belongs to the GerABKA family.

349161:DRED RS01240
gene id: 349161:DRED_RS01240
uniprot id: A4J123
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

349161:DRED RS07965
gene id: 349161:DRED_RS07965
uniprot id: A4J4K6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

349161:DRED RS16975
gene id: 349161:DRED_RS16975
uniprot id: A4J9E1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

349161:DRED RS01790
gene id: 349161:DRED_RS01790
uniprot id: A4J1D2
names: Similarity
messages: Belongs to the CAPAB/TerDEXZ family.

349161:DRED RS00325
gene id: 349161:DRED_RS00325
uniprot id: A4J0K2
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

349161:DRED RS09190
gene id: 349161:DRED_RS09190
uniprot id: A4J589
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

349161:DRED RS14515
gene id: 349161:DRED_RS14515
uniprot id: A4J822
names: Similarity
messages: Belongs to the DtxR/MntR family.

349161:DRED RS10990
gene id: 349161:DRED_RS10990
uniprot id: A4J678
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

349161:DRED RS13120
gene id: 349161:DRED_RS13120
uniprot id: A4J7C0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

349161:DRED RS17885
gene id: 349161:DRED_RS17885
uniprot id: A4J3W5
names: Similarity
messages: Belongs to the peptidase S11 family.

349161:DRED RS17480
gene id: 349161:DRED_RS17480
uniprot id: A4J9N9
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

349161:DRED RS10275
gene id: 349161:DRED_RS10275
uniprot id: A4J5U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

349161:DRED RS13620
gene id: 349161:DRED_RS13620
uniprot id: A4J7L7
names: Similarity
messages: Belongs to the peptidase S16 family.