345632:GPICK RS08095
gene id: 345632:GPICK_RS08095
uniprot id: A0A0B5BDU1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS15180
gene id: 345632:GPICK_RS15180
uniprot id: A0A0B5BCR6
names: Similarity
messages: Belongs to the peptidase A31 family.

345632:GPICK RS13895
gene id: 345632:GPICK_RS13895
uniprot id: A0A0B5BCS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS00160
gene id: 345632:GPICK_RS00160
uniprot id: A0A0B5BAL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

345632:GPICK RS07105
gene id: 345632:GPICK_RS07105
uniprot id: A0A0B5B9C4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

345632:GPICK RS06075
gene id: 345632:GPICK_RS06075
uniprot id: A0A0B5BD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

345632:GPICK RS05290
gene id: 345632:GPICK_RS05290
uniprot id: A0A0B5B8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

345632:GPICK RS08200
gene id: 345632:GPICK_RS08200
uniprot id: A0A0B5BDT8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

345632:GPICK RS13490
gene id: 345632:GPICK_RS13490
uniprot id: A0A0B5BGD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

345632:GPICK RS06525
gene id: 345632:GPICK_RS06525
uniprot id: A0A0B5BG88
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

345632:GPICK RS05635
gene id: 345632:GPICK_RS05635
uniprot id: A0A0B5B8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

345632:GPICK RS11115
gene id: 345632:GPICK_RS11115
uniprot id: A0A0B5BBB7
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

345632:GPICK RS14445
gene id: 345632:GPICK_RS14445
uniprot id: A0A0B5BGX2
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

345632:GPICK RS10315
gene id: 345632:GPICK_RS10315
uniprot id: A0A0B5BGP6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

345632:GPICK RS07055
gene id: 345632:GPICK_RS07055
uniprot id: A0A0B5B9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

345632:GPICK RS06535
gene id: 345632:GPICK_RS06535
uniprot id: A0A0B5B942
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

345632:GPICK RS12560
gene id: 345632:GPICK_RS12560
uniprot id: A0A0B5BHX3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

345632:GPICK RS12970
gene id: 345632:GPICK_RS12970
uniprot id: A0A0B5BCA3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

345632:GPICK RS00505
gene id: 345632:GPICK_RS00505
uniprot id: A0A0B5B691
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS16085
gene id: 345632:GPICK_RS16085
uniprot id: A0A0B5BKT8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

345632:GPICK RS06545
gene id: 345632:GPICK_RS06545
uniprot id: A0A0B5BD85
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

345632:GPICK RS02365
gene id: 345632:GPICK_RS02365
uniprot id: A0A0B5BBM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

345632:GPICK RS13555
gene id: 345632:GPICK_RS13555
uniprot id: A0A0B5BCL6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

345632:GPICK RS00625
gene id: 345632:GPICK_RS00625
uniprot id: A0A0B5BAU3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS11220
gene id: 345632:GPICK_RS11220
uniprot id: A0A0B5BBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

345632:GPICK RS11470
gene id: 345632:GPICK_RS11470
uniprot id: A0A0B5BAV9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

345632:GPICK RS00550
gene id: 345632:GPICK_RS00550
uniprot id: A0A0B5BBY2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS13720
gene id: 345632:GPICK_RS13720
uniprot id: A0A0B5BJK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

345632:GPICK RS03900
gene id: 345632:GPICK_RS03900
uniprot id: A0A0B5BEY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

345632:GPICK RS09250
gene id: 345632:GPICK_RS09250
uniprot id: A0A0B5BG66
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

345632:GPICK RS13160
gene id: 345632:GPICK_RS13160
uniprot id: A0A0B5BCD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

345632:GPICK RS08215
gene id: 345632:GPICK_RS08215
uniprot id: A0A0B5BDZ3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01420
gene id: 345632:GPICK_RS01420
uniprot id: A0A0B5BCB1
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS00380
gene id: 345632:GPICK_RS00380
uniprot id: A0A0B5BBU4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

345632:GPICK RS08145
gene id: 345632:GPICK_RS08145
uniprot id: A0A0B5B9F4
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

345632:GPICK RS08990
gene id: 345632:GPICK_RS08990
uniprot id: A0A0B5BK81
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS08315
gene id: 345632:GPICK_RS08315
uniprot id: A0A0B5BH57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

345632:GPICK RS10310
gene id: 345632:GPICK_RS10310
uniprot id: A0A0B5BEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

345632:GPICK RS03660
gene id: 345632:GPICK_RS03660
uniprot id: A0A0B5BEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

345632:GPICK RS13515
gene id: 345632:GPICK_RS13515
uniprot id: A0A0B5BGE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

345632:GPICK RS09855
gene id: 345632:GPICK_RS09855
uniprot id: A0A0B5BGH8
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

345632:GPICK RS04415
gene id: 345632:GPICK_RS04415
uniprot id: A0A0B5B7Z8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

345632:GPICK RS16335
gene id: 345632:GPICK_RS16335
uniprot id: A0A0B5BJQ4
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

345632:GPICK RS00770
gene id: 345632:GPICK_RS00770
uniprot id: A0A0B5BAX2
names: Similarity
messages: Belongs to the HypE family.

345632:GPICK RS12790
gene id: 345632:GPICK_RS12790
uniprot id: A0A0B5BJ77
names: Similarity
messages: Belongs to the hemerythrin family.

345632:GPICK RS16220
gene id: 345632:GPICK_RS16220
uniprot id: A0A0B5BE00
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

345632:GPICK RS06030
gene id: 345632:GPICK_RS06030
uniprot id: A0A0B5BEM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

345632:GPICK RS03795
gene id: 345632:GPICK_RS03795
uniprot id: A0A0B5BC45
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

345632:GPICK RS11755
gene id: 345632:GPICK_RS11755
uniprot id: A0A0B5BBN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

345632:GPICK RS15785
gene id: 345632:GPICK_RS15785
uniprot id: A0A0B5BJG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

345632:GPICK RS02625
gene id: 345632:GPICK_RS02625
uniprot id: A0A0B5B795
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

345632:GPICK RS05555
gene id: 345632:GPICK_RS05555
uniprot id: A0A0B5BFT1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

345632:GPICK RS02835
gene id: 345632:GPICK_RS02835
uniprot id: A0A0B5B7C5
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15290
gene id: 345632:GPICK_RS15290
uniprot id: A0A0B5BIH0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

345632:GPICK RS07075
gene id: 345632:GPICK_RS07075
uniprot id: A0A0B5BGI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

345632:GPICK RS07845
gene id: 345632:GPICK_RS07845
uniprot id: A0A0B5B961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

345632:GPICK RS00330
gene id: 345632:GPICK_RS00330
uniprot id: A0A0B5BBT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

345632:GPICK RS00395
gene id: 345632:GPICK_RS00395
uniprot id: A0A0B5B690
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Heterodimer of a large and a small subunit.

345632:GPICK RS10365
gene id: 345632:GPICK_RS10365
uniprot id: A0A0B5BGQ6
names: Similarity
messages: Belongs to the YicC/YloC family.

345632:GPICK RS05550
gene id: 345632:GPICK_RS05550
uniprot id: A0A0B5BEE9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS07835
gene id: 345632:GPICK_RS07835
uniprot id: A0A0B5BGU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS14155
gene id: 345632:GPICK_RS14155
uniprot id: A0A0B5BIP8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

345632:GPICK RS10900
gene id: 345632:GPICK_RS10900
uniprot id: A0A0B5BAN2
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

345632:GPICK RS11570
gene id: 345632:GPICK_RS11570
uniprot id: A0A0B5BFJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

345632:GPICK RS15305
gene id: 345632:GPICK_RS15305
uniprot id: A0A0B5BKF8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS03275
gene id: 345632:GPICK_RS03275
uniprot id: A0A0B5B7I0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

345632:GPICK RS09395
gene id: 345632:GPICK_RS09395
uniprot id: A0A0B5B9Y8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

345632:GPICK RS06025
gene id: 345632:GPICK_RS06025
uniprot id: A0A0B5BD15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

345632:GPICK RS12000
gene id: 345632:GPICK_RS12000
uniprot id: A0A0B5BHM6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

345632:GPICK RS00250
gene id: 345632:GPICK_RS00250
uniprot id: A0A0B5BBS0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS03945
gene id: 345632:GPICK_RS03945
uniprot id: A0A0B5BC64
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

345632:GPICK RS00370
gene id: 345632:GPICK_RS00370
uniprot id: A0A0B5B687
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

345632:GPICK RS15020
gene id: 345632:GPICK_RS15020
uniprot id: A0A0B5BKE8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

345632:GPICK RS15230
gene id: 345632:GPICK_RS15230
uniprot id: A0A0B5BCS4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

345632:GPICK RS03460
gene id: 345632:GPICK_RS03460
uniprot id: A0A0B5B7Q2
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

345632:GPICK RS08665
gene id: 345632:GPICK_RS08665
uniprot id: A0A0B5BA10
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08230
gene id: 345632:GPICK_RS08230
uniprot id: A0A0B5B9U4
names: Similarity
messages: Belongs to the leucine-binding protein family.

345632:GPICK RS14905
gene id: 345632:GPICK_RS14905
uniprot id: A0A0B5BDD1
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

345632:GPICK RS11940
gene id: 345632:GPICK_RS11940
uniprot id: A0A0B5BDX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

345632:GPICK RS07955
gene id: 345632:GPICK_RS07955
uniprot id: A0A0B5BDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS10655
gene id: 345632:GPICK_RS10655
uniprot id: A0A0B5BI79
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS11565
gene id: 345632:GPICK_RS11565
uniprot id: A0A0B5BAX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

345632:GPICK RS00195
gene id: 345632:GPICK_RS00195
uniprot id: A0A0B5BD25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS07940
gene id: 345632:GPICK_RS07940
uniprot id: A0A0B5BGX1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

345632:GPICK RS12605
gene id: 345632:GPICK_RS12605
uniprot id: A0A0B5BC30
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS10040
gene id: 345632:GPICK_RS10040
uniprot id: A0A0B5BHW9
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

345632:GPICK RS09410
gene id: 345632:GPICK_RS09410
uniprot id: A0A0B5BHM9
names: Similarity
messages: Belongs to the HdrA family.

345632:GPICK RS01310
gene id: 345632:GPICK_RS01310
uniprot id: A0A0B5BDN9
names: Subcellular Location Annotation
messages: Nucleus

345632:GPICK RS12420
gene id: 345632:GPICK_RS12420
uniprot id: A0A0B5BHU7
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

345632:GPICK RS15220
gene id: 345632:GPICK_RS15220
uniprot id: A0A0B5BKE2
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

345632:GPICK RS12365
gene id: 345632:GPICK_RS12365
uniprot id: A0A0B5BJ15
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

345632:GPICK RS14350
gene id: 345632:GPICK_RS14350
uniprot id: A0A0B5BD30
names: Similarity
messages: Belongs to the UPF0758 family.

345632:GPICK RS05800
gene id: 345632:GPICK_RS05800
uniprot id: A0A0B5B8R5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

345632:GPICK RS08465
gene id: 345632:GPICK_RS08465
uniprot id: A0A0B5B9K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

345632:GPICK RS02865
gene id: 345632:GPICK_RS02865
uniprot id: A0A0B5B7F9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

345632:GPICK RS08265
gene id: 345632:GPICK_RS08265
uniprot id: A0A0B5BE02
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

345632:GPICK RS14190
gene id: 345632:GPICK_RS14190
uniprot id: A0A0B5BD04
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

345632:GPICK RS00850
gene id: 345632:GPICK_RS00850
uniprot id: A0A0B5BAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

345632:GPICK RS06235
gene id: 345632:GPICK_RS06235
uniprot id: A0A0B5B8K4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

345632:GPICK RS05570
gene id: 345632:GPICK_RS05570
uniprot id: A0A0B5B8C6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

345632:GPICK RS06825
gene id: 345632:GPICK_RS06825
uniprot id: A0A0B5B8T4
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

345632:GPICK RS11990
gene id: 345632:GPICK_RS11990
uniprot id: A0A0B5BB35
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

345632:GPICK RS15515
gene id: 345632:GPICK_RS15515
uniprot id: A0A0B5BDN8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

345632:GPICK RS08295
gene id: 345632:GPICK_RS08295
uniprot id: A0A0B5BIA3
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

345632:GPICK RS00820
gene id: 345632:GPICK_RS00820
uniprot id: A0A0B5B6F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS00360
gene id: 345632:GPICK_RS00360
uniprot id: A0A0B5BD64
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

345632:GPICK RS07425
gene id: 345632:GPICK_RS07425
uniprot id: A0A0B5BF99
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

345632:GPICK RS05360
gene id: 345632:GPICK_RS05360
uniprot id: A0A0B5BCR4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

345632:GPICK RS14520
gene id: 345632:GPICK_RS14520
uniprot id: A0A0B5BK16
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS08005
gene id: 345632:GPICK_RS08005
uniprot id: A0A0B5BI97
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

345632:GPICK RS10685
gene id: 345632:GPICK_RS10685
uniprot id: A0A0B5BI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS12680
gene id: 345632:GPICK_RS12680
uniprot id: A0A0B5BJ62
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

345632:GPICK RS13810
gene id: 345632:GPICK_RS13810
uniprot id: A0A0B5BJL8
names: Similarity
messages: Belongs to the UPF0166 family.

345632:GPICK RS14205
gene id: 345632:GPICK_RS14205
uniprot id: A0A0B5BIR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS03410
gene id: 345632:GPICK_RS03410
uniprot id: A0A0B5B7P1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

345632:GPICK RS07025
gene id: 345632:GPICK_RS07025
uniprot id: A0A0B5B9A6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

345632:GPICK RS01890
gene id: 345632:GPICK_RS01890
uniprot id: A0A0B5B6Z3
names: Similarity
messages: Belongs to the cytochrome c-552 family.

345632:GPICK RS03515
gene id: 345632:GPICK_RS03515
uniprot id: A0A0B5B7L5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

345632:GPICK RS15465
gene id: 345632:GPICK_RS15465
uniprot id: A0A0B5BDM8
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

345632:GPICK RS08425
gene id: 345632:GPICK_RS08425
uniprot id: A0A0B5B9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

345632:GPICK RS14505
gene id: 345632:GPICK_RS14505
uniprot id: A0A0B5BCH9
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

345632:GPICK RS08150
gene id: 345632:GPICK_RS08150
uniprot id: A0A0B5BDY0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS13120
gene id: 345632:GPICK_RS13120
uniprot id: A0A0B5BJC1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS10690
gene id: 345632:GPICK_RS10690
uniprot id: A0A0B5BB23
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

345632:GPICK RS07260
gene id: 345632:GPICK_RS07260
uniprot id: A0A0B5BGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

345632:GPICK RS00175
gene id: 345632:GPICK_RS00175
uniprot id: A0A0B5B620
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

345632:GPICK RS11740
gene id: 345632:GPICK_RS11740
uniprot id: A0A0B5BFM2
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

345632:GPICK RS01155
gene id: 345632:GPICK_RS01155
uniprot id: A0A0B5B6K1
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS15600
gene id: 345632:GPICK_RS15600
uniprot id: A0A0B5BDQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

345632:GPICK RS13130
gene id: 345632:GPICK_RS13130
uniprot id: A0A0B5BBM2
names: Similarity
messages: Belongs to the UPF0102 family.

345632:GPICK RS15120
gene id: 345632:GPICK_RS15120
uniprot id: A0A0B5BDG4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

345632:GPICK RS01170
gene id: 345632:GPICK_RS01170
uniprot id: A0A0B5BC87
names: Similarity
messages: Belongs to the UPF0751 family.

345632:GPICK RS16230
gene id: 345632:GPICK_RS16230
uniprot id: A0A0B5BHR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

345632:GPICK RS15520
gene id: 345632:GPICK_RS15520
uniprot id: A0A0B5BCY4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

345632:GPICK RS05150
gene id: 345632:GPICK_RS05150
uniprot id: A0A0B5BFL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

345632:GPICK RS11615
gene id: 345632:GPICK_RS11615
uniprot id: A0A0B5BHG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

345632:GPICK RS12245
gene id: 345632:GPICK_RS12245
uniprot id: A0A0B5BHR8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

345632:GPICK RS03695
gene id: 345632:GPICK_RS03695
uniprot id: A0A0B5BDL6
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS16140
gene id: 345632:GPICK_RS16140
uniprot id: A0A0B5BDY7
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS13015
gene id: 345632:GPICK_RS13015
uniprot id: A0A0B5BJB0
names: Similarity
messages: Belongs to the NifX/NifY family.

345632:GPICK RS13935
gene id: 345632:GPICK_RS13935
uniprot id: A0A0B5BGK0
names: Similarity
messages: Belongs to the DEAD box helicase family.

345632:GPICK RS11795
gene id: 345632:GPICK_RS11795
uniprot id: A0A0B5BFM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

345632:GPICK RS13745
gene id: 345632:GPICK_RS13745
uniprot id: A0A0B5BGG6
names: Similarity
messages: Belongs to the PilY1 family.

345632:GPICK RS13880
gene id: 345632:GPICK_RS13880
uniprot id: A0A0B5BGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

345632:GPICK RS00545
gene id: 345632:GPICK_RS00545
uniprot id: A0A0B5BAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS08830
gene id: 345632:GPICK_RS08830
uniprot id: A0A0B5B9Q2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS15930
gene id: 345632:GPICK_RS15930
uniprot id: A0A0B5BJI1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS10345
gene id: 345632:GPICK_RS10345
uniprot id: A0A0B5BI26
names: Similarity
messages: Belongs to the RutC family.

345632:GPICK RS09375
gene id: 345632:GPICK_RS09375
uniprot id: A0A0B5BEE7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

345632:GPICK RS02445
gene id: 345632:GPICK_RS02445
uniprot id: A0A0B5BCX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

345632:GPICK RS09525
gene id: 345632:GPICK_RS09525
uniprot id: A0A0B5BGC0
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

345632:GPICK RS13390
gene id: 345632:GPICK_RS13390
uniprot id: A0A0B5BJF9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

345632:GPICK RS11235
gene id: 345632:GPICK_RS11235
uniprot id: A0A0B5BHA4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

345632:GPICK RS13040
gene id: 345632:GPICK_RS13040
uniprot id: A0A0B5BJB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

345632:GPICK RS08025
gene id: 345632:GPICK_RS08025
uniprot id: A0A0B5BGZ0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS11790
gene id: 345632:GPICK_RS11790
uniprot id: A0A0B5BLI2
names: Similarity
messages: Belongs to the TrpF family.

345632:GPICK RS00535
gene id: 345632:GPICK_RS00535
uniprot id: A0A0B5B6A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS11270
gene id: 345632:GPICK_RS11270
uniprot id: A0A0B5BIK6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

345632:GPICK RS03390
gene id: 345632:GPICK_RS03390
uniprot id: A0A0B5BDC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

345632:GPICK RS09350
gene id: 345632:GPICK_RS09350
uniprot id: A0A0B5BEE3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

345632:GPICK RS09675
gene id: 345632:GPICK_RS09675
uniprot id: A0A0B5BEJ7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

345632:GPICK RS03250
gene id: 345632:GPICK_RS03250
uniprot id: A0A0B5B7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

345632:GPICK RS00020
gene id: 345632:GPICK_RS00020
uniprot id: A0A0B5B654
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

345632:GPICK RS05120
gene id: 345632:GPICK_RS05120
uniprot id: A0A0B5BE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

345632:GPICK RS01720
gene id: 345632:GPICK_RS01720
uniprot id: A0A0B5B6W4
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the nitrate reductase NapAB complex composed of NapA and NapB.
messages: Heterodimer of a large and a small subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.
messages: Secreted

345632:GPICK RS00665
gene id: 345632:GPICK_RS00665
uniprot id: A0A0B5BDC4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

345632:GPICK RS05875
gene id: 345632:GPICK_RS05875
uniprot id: A0A0B5B8F8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS06060
gene id: 345632:GPICK_RS06060
uniprot id: A0A0B5BFZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

345632:GPICK RS02615
gene id: 345632:GPICK_RS02615
uniprot id: A0A0B5BCY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

345632:GPICK RS06010
gene id: 345632:GPICK_RS06010
uniprot id: A0A0B5BFY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

345632:GPICK RS11895
gene id: 345632:GPICK_RS11895
uniprot id: A0A0B5BBS6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

345632:GPICK RS13550
gene id: 345632:GPICK_RS13550
uniprot id: A0A0B5BJI0
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

345632:GPICK RS11185
gene id: 345632:GPICK_RS11185
uniprot id: A0A0B5BH94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

345632:GPICK RS15660
gene id: 345632:GPICK_RS15660
uniprot id: A0A0B5BD13
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

345632:GPICK RS02390
gene id: 345632:GPICK_RS02390
uniprot id: A0A0B5BBN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

345632:GPICK RS12495
gene id: 345632:GPICK_RS12495
uniprot id: A0A0B5BC11
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS12200
gene id: 345632:GPICK_RS12200
uniprot id: A0A0B5BIY8
names: Similarity
messages: Belongs to the peptidase M16 family.

345632:GPICK RS03400
gene id: 345632:GPICK_RS03400
uniprot id: A0A0B5B7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

345632:GPICK RS01835
gene id: 345632:GPICK_RS01835
uniprot id: A0A0B5B6W1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

345632:GPICK RS11785
gene id: 345632:GPICK_RS11785
uniprot id: A0A0B5BB03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

345632:GPICK RS13670
gene id: 345632:GPICK_RS13670
uniprot id: A0A0B5BBZ4
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

345632:GPICK RS05020
gene id: 345632:GPICK_RS05020
uniprot id: A0A0B5BFG5
names: Similarity
messages: Belongs to the UPF0225 family.

345632:GPICK RS15905
gene id: 345632:GPICK_RS15905
uniprot id: A0A0B5BJH7
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03380
gene id: 345632:GPICK_RS03380
uniprot id: A0A0B5B7N6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

345632:GPICK RS00440
gene id: 345632:GPICK_RS00440
uniprot id: A0A0B5BD82
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

345632:GPICK RS02840
gene id: 345632:GPICK_RS02840
uniprot id: A0A0B5B7F4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

345632:GPICK RS13020
gene id: 345632:GPICK_RS13020
uniprot id: A0A0B5BCB2
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

345632:GPICK RS14935
gene id: 345632:GPICK_RS14935
uniprot id: A0A0B5BCN3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

345632:GPICK RS00730
gene id: 345632:GPICK_RS00730
uniprot id: A0A0B5B6D1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS04790
gene id: 345632:GPICK_RS04790
uniprot id: A0A0B5BE15
names: Similarity
messages: Belongs to the peptidase A31 family.

345632:GPICK RS10005
gene id: 345632:GPICK_RS10005
uniprot id: A0A0B5BGJ9
names: Similarity
messages: Belongs to the histone deacetylase family.

345632:GPICK RS03300
gene id: 345632:GPICK_RS03300
uniprot id: A0A0B5B7I4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

345632:GPICK RS01370
gene id: 345632:GPICK_RS01370
uniprot id: A0A0B5B6N2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS06405
gene id: 345632:GPICK_RS06405
uniprot id: A0A0B5BET8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

345632:GPICK RS03480
gene id: 345632:GPICK_RS03480
uniprot id: A0A0B5B7K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS02295
gene id: 345632:GPICK_RS02295
uniprot id: A0A0B5BDJ6
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

345632:GPICK RS04595
gene id: 345632:GPICK_RS04595
uniprot id: A0A0B5B862
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

345632:GPICK RS00620
gene id: 345632:GPICK_RS00620
uniprot id: A0A0B5B6C2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

345632:GPICK RS15330
gene id: 345632:GPICK_RS15330
uniprot id: A0A0B5BKG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

345632:GPICK RS11495
gene id: 345632:GPICK_RS11495
uniprot id: A0A0B5BHE2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

345632:GPICK RS16385
gene id: 345632:GPICK_RS16385
uniprot id: A0A0B5BJR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

345632:GPICK RS07920
gene id: 345632:GPICK_RS07920
uniprot id: A0A0B5B9M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

345632:GPICK RS06960
gene id: 345632:GPICK_RS06960
uniprot id: A0A0B5BDD9
names: Similarity
messages: Belongs to the CFA/CMAS family.

345632:GPICK RS10400
gene id: 345632:GPICK_RS10400
uniprot id: A0A0B5BAW2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

345632:GPICK RS14835
gene id: 345632:GPICK_RS14835
uniprot id: A0A0B5BH22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

345632:GPICK RS16485
gene id: 345632:GPICK_RS16485
uniprot id: A0A0B5BL14
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

345632:GPICK RS16120
gene id: 345632:GPICK_RS16120
uniprot id: A0A0B5BD91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

345632:GPICK RS03855
gene id: 345632:GPICK_RS03855
uniprot id: A0A0B5B7R5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

345632:GPICK RS12395
gene id: 345632:GPICK_RS12395
uniprot id: A0A0B5BJ19
names: Similarity
messages: Belongs to the SfsA family.

345632:GPICK RS10545
gene id: 345632:GPICK_RS10545
uniprot id: A0A0B5BI62
names: Similarity
messages: Belongs to the peptidase C40 family.

345632:GPICK RS09830
gene id: 345632:GPICK_RS09830
uniprot id: A0A0B5BGH2
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS11260
gene id: 345632:GPICK_RS11260
uniprot id: A0A0B5BFF9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

345632:GPICK RS11760
gene id: 345632:GPICK_RS11760
uniprot id: A0A0B5BAZ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

345632:GPICK RS01980
gene id: 345632:GPICK_RS01980
uniprot id: A0A0B5BCK6
names: Similarity
messages: Belongs to the threonine aldolase family.

345632:GPICK RS09865
gene id: 345632:GPICK_RS09865
uniprot id: A0A0B5BAL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

345632:GPICK RS02740
gene id: 345632:GPICK_RS02740
uniprot id: A0A0B5B7E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS05880
gene id: 345632:GPICK_RS05880
uniprot id: A0A0B5BCZ0
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS06050
gene id: 345632:GPICK_RS06050
uniprot id: A0A0B5BD20
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS15735
gene id: 345632:GPICK_RS15735
uniprot id: A0A0B5BKN3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

345632:GPICK RS10945
gene id: 345632:GPICK_RS10945
uniprot id: A0A0B5BB76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

345632:GPICK RS14815
gene id: 345632:GPICK_RS14815
uniprot id: A0A0B5BJ17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

345632:GPICK RS05430
gene id: 345632:GPICK_RS05430
uniprot id: A0A0B5B8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

345632:GPICK RS06035
gene id: 345632:GPICK_RS06035
uniprot id: A0A0B5BFZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS07930
gene id: 345632:GPICK_RS07930
uniprot id: A0A0B5BDQ9
names: Similarity
messages: Belongs to the fabD family.

345632:GPICK RS08395
gene id: 345632:GPICK_RS08395
uniprot id: A0A0B5BH68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

345632:GPICK RS03450
gene id: 345632:GPICK_RS03450
uniprot id: A0A0B5BER7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

345632:GPICK RS09825
gene id: 345632:GPICK_RS09825
uniprot id: A0A0B5BEM4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

345632:GPICK RS09180
gene id: 345632:GPICK_RS09180
uniprot id: A0A0B5B9U7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS03950
gene id: 345632:GPICK_RS03950
uniprot id: A0A0B5BDM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

345632:GPICK RS00260
gene id: 345632:GPICK_RS00260
uniprot id: A0A0B5BJT8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

345632:GPICK RS03880
gene id: 345632:GPICK_RS03880
uniprot id: A0A0B5B7S1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS11750
gene id: 345632:GPICK_RS11750
uniprot id: A0A0B5BIQ9
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

345632:GPICK RS06460
gene id: 345632:GPICK_RS06460
uniprot id: A0A0B5BG78
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

345632:GPICK RS13280
gene id: 345632:GPICK_RS13280
uniprot id: A0A0B5BCG0
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

345632:GPICK RS13475
gene id: 345632:GPICK_RS13475
uniprot id: A0A0B5BJG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS02230
gene id: 345632:GPICK_RS02230
uniprot id: A0A0B5BE75
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

345632:GPICK RS14145
gene id: 345632:GPICK_RS14145
uniprot id: A0A0B5BCD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

345632:GPICK RS00765
gene id: 345632:GPICK_RS00765
uniprot id: A0A0B5B6E9
names: Similarity
messages: Belongs to the HypD family.

345632:GPICK RS13565
gene id: 345632:GPICK_RS13565
uniprot id: A0A0B5BLK4
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

345632:GPICK RS02640
gene id: 345632:GPICK_RS02640
uniprot id: A0A0B5BBQ0
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15880
gene id: 345632:GPICK_RS15880
uniprot id: A0A0B5BDV3
names: Function
names: Similarity
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.

345632:GPICK RS05785
gene id: 345632:GPICK_RS05785
uniprot id: A0A0B5BCX6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS05165
gene id: 345632:GPICK_RS05165
uniprot id: A0A0B5BCN9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

345632:GPICK RS07615
gene id: 345632:GPICK_RS07615
uniprot id: A0A0B5BDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

345632:GPICK RS15525
gene id: 345632:GPICK_RS15525
uniprot id: A0A0B5BHC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS14110
gene id: 345632:GPICK_RS14110
uniprot id: A0A0B5BCZ2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS02180
gene id: 345632:GPICK_RS02180
uniprot id: A0A0B5BE68
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

345632:GPICK RS14020
gene id: 345632:GPICK_RS14020
uniprot id: A0A0B5BCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS15270
gene id: 345632:GPICK_RS15270
uniprot id: A0A0B5BKF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS14250
gene id: 345632:GPICK_RS14250
uniprot id: A0A0B5BCE9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS00880
gene id: 345632:GPICK_RS00880
uniprot id: A0A0B5BAZ7
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS05890
gene id: 345632:GPICK_RS05890
uniprot id: A0A0B5BEJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

345632:GPICK RS00035
gene id: 345632:GPICK_RS00035
uniprot id: A0A0B5BD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

345632:GPICK RS08220
gene id: 345632:GPICK_RS08220
uniprot id: A0A0B5BFQ5
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS07065
gene id: 345632:GPICK_RS07065
uniprot id: A0A0B5BDF2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

345632:GPICK RS07735
gene id: 345632:GPICK_RS07735
uniprot id: A0A0B5BFE4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

345632:GPICK RS06655
gene id: 345632:GPICK_RS06655
uniprot id: A0A0B5BDA1
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

345632:GPICK RS07490
gene id: 345632:GPICK_RS07490
uniprot id: A0A0B5BFA9
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

345632:GPICK RS07390
gene id: 345632:GPICK_RS07390
uniprot id: A0A0B5B902
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01275
gene id: 345632:GPICK_RS01275
uniprot id: A0A0B5BDN4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

345632:GPICK RS10995
gene id: 345632:GPICK_RS10995
uniprot id: A0A0B5BKA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS05995
gene id: 345632:GPICK_RS05995
uniprot id: A0A0B5BD10
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS06455
gene id: 345632:GPICK_RS06455
uniprot id: A0A0B5BEU8
names: Similarity
messages: Belongs to the P(II) protein family.

345632:GPICK RS02280
gene id: 345632:GPICK_RS02280
uniprot id: A0A0B5BCV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS03425
gene id: 345632:GPICK_RS03425
uniprot id: A0A0B5BER4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS16355
gene id: 345632:GPICK_RS16355
uniprot id: A0A0B5BHT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

345632:GPICK RS08610
gene id: 345632:GPICK_RS08610
uniprot id: A0A0B5BA01
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS00650
gene id: 345632:GPICK_RS00650
uniprot id: A0A0B5B6C7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

345632:GPICK RS13380
gene id: 345632:GPICK_RS13380
uniprot id: A0A0B5BI76
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

345632:GPICK RS10670
gene id: 345632:GPICK_RS10670
uniprot id: A0A0B5BAJ0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS00525
gene id: 345632:GPICK_RS00525
uniprot id: A0A0B5BD98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

345632:GPICK RS11855
gene id: 345632:GPICK_RS11855
uniprot id: A0A0B5BHK4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

345632:GPICK RS02535
gene id: 345632:GPICK_RS02535
uniprot id: A0A0B5BBP3
names: Similarity
messages: Belongs to the MotB family.

345632:GPICK RS03325
gene id: 345632:GPICK_RS03325
uniprot id: A0A0B5B7I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

345632:GPICK RS14650
gene id: 345632:GPICK_RS14650
uniprot id: A0A0B5BCK3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

345632:GPICK RS06195
gene id: 345632:GPICK_RS06195
uniprot id: A0A0B5BG26
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS04495
gene id: 345632:GPICK_RS04495
uniprot id: A0A0B5BCC5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

345632:GPICK RS16430
gene id: 345632:GPICK_RS16430
uniprot id: A0A0B5BDF5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

345632:GPICK RS09325
gene id: 345632:GPICK_RS09325
uniprot id: A0A0B5BED9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

345632:GPICK RS03415
gene id: 345632:GPICK_RS03415
uniprot id: A0A0B5BBZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

345632:GPICK RS06425
gene id: 345632:GPICK_RS06425
uniprot id: A0A0B5BD70
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00980
gene id: 345632:GPICK_RS00980
uniprot id: A0A0B5B6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

345632:GPICK RS02245
gene id: 345632:GPICK_RS02245
uniprot id: A0A0B5BBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

345632:GPICK RS10225
gene id: 345632:GPICK_RS10225
uniprot id: A0A0B5BDW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

345632:GPICK RS08905
gene id: 345632:GPICK_RS08905
uniprot id: A0A0B5BG08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

345632:GPICK RS05925
gene id: 345632:GPICK_RS05925
uniprot id: A0A0B5B8T1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

345632:GPICK RS07400
gene id: 345632:GPICK_RS07400
uniprot id: A0A0B5BF94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS05590
gene id: 345632:GPICK_RS05590
uniprot id: A0A0B5B8P2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

345632:GPICK RS05310
gene id: 345632:GPICK_RS05310
uniprot id: A0A0B5BEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

345632:GPICK RS07405
gene id: 345632:GPICK_RS07405
uniprot id: A0A0B5BGN0
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

345632:GPICK RS02095
gene id: 345632:GPICK_RS02095
uniprot id: A0A0B5BE53
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

345632:GPICK RS02705
gene id: 345632:GPICK_RS02705
uniprot id: A0A0B5B7A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Membrane

345632:GPICK RS05840
gene id: 345632:GPICK_RS05840
uniprot id: A0A0B5BDR1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS11055
gene id: 345632:GPICK_RS11055
uniprot id: A0A0B5BIE9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS16165
gene id: 345632:GPICK_RS16165
uniprot id: A0A0B5BDY9
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

345632:GPICK RS04030
gene id: 345632:GPICK_RS04030
uniprot id: A0A0B5B7V0
names: Similarity
messages: Belongs to the UPF0751 family.

345632:GPICK RS11300
gene id: 345632:GPICK_RS11300
uniprot id: A0A0B5BBF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

345632:GPICK RS06875
gene id: 345632:GPICK_RS06875
uniprot id: A0A0B5BGF8
names: Similarity
messages: Belongs to the Lgt family.

345632:GPICK RS09780
gene id: 345632:GPICK_RS09780
uniprot id: A0A0B5BHS8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS02500
gene id: 345632:GPICK_RS02500
uniprot id: A0A0B5BBP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

345632:GPICK RS08940
gene id: 345632:GPICK_RS08940
uniprot id: A0A0B5BHF3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

345632:GPICK RS03160
gene id: 345632:GPICK_RS03160
uniprot id: A0A0B5B7K6
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS11170
gene id: 345632:GPICK_RS11170
uniprot id: A0A0B5BAS8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS06390
gene id: 345632:GPICK_RS06390
uniprot id: A0A0B5B8L9
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

345632:GPICK RS16370
gene id: 345632:GPICK_RS16370
uniprot id: A0A0B5BE33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

345632:GPICK RS15640
gene id: 345632:GPICK_RS15640
uniprot id: A0A0B5BHF1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03305
gene id: 345632:GPICK_RS03305
uniprot id: A0A0B5B7M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

345632:GPICK RS08415
gene id: 345632:GPICK_RS08415
uniprot id: A0A0B5BFT4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

345632:GPICK RS08030
gene id: 345632:GPICK_RS08030
uniprot id: A0A0B5B9Q3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

345632:GPICK RS08130
gene id: 345632:GPICK_RS08130
uniprot id: A0A0B5BH37
names: Similarity
messages: Belongs to the Skp family.

345632:GPICK RS01840
gene id: 345632:GPICK_RS01840
uniprot id: A0A0B5B6Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS09650
gene id: 345632:GPICK_RS09650
uniprot id: A0A0B5BHR1
names: Similarity
messages: Belongs to the heat shock protein 70 family.

345632:GPICK RS06290
gene id: 345632:GPICK_RS06290
uniprot id: A0A0B5BD55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

345632:GPICK RS06510
gene id: 345632:GPICK_RS06510
uniprot id: A0A0B5BD81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

345632:GPICK RS03530
gene id: 345632:GPICK_RS03530
uniprot id: A0A0B5BDF4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

345632:GPICK RS04525
gene id: 345632:GPICK_RS04525
uniprot id: A0A0B5BCC9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

345632:GPICK RS13630
gene id: 345632:GPICK_RS13630
uniprot id: A0A0B5BJI9
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

345632:GPICK RS01505
gene id: 345632:GPICK_RS01505
uniprot id: A0A0B5B6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

345632:GPICK RS00270
gene id: 345632:GPICK_RS00270
uniprot id: A0A0B5B676
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS14555
gene id: 345632:GPICK_RS14555
uniprot id: A0A0B5BCI8
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS14150
gene id: 345632:GPICK_RS14150
uniprot id: A0A0B5BGS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

345632:GPICK RS07745
gene id: 345632:GPICK_RS07745
uniprot id: A0A0B5B9K2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01570
gene id: 345632:GPICK_RS01570
uniprot id: A0A0B5BBA3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS16345
gene id: 345632:GPICK_RS16345
uniprot id: A0A0B5BE27
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

345632:GPICK RS03940
gene id: 345632:GPICK_RS03940
uniprot id: A0A0B5B7V2
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

345632:GPICK RS02135
gene id: 345632:GPICK_RS02135
uniprot id: A0A0B5B751
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

345632:GPICK RS07350
gene id: 345632:GPICK_RS07350
uniprot id: A0A0B5BF85
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS05395
gene id: 345632:GPICK_RS05395
uniprot id: A0A0B5BFP7
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

345632:GPICK RS04775
gene id: 345632:GPICK_RS04775
uniprot id: A0A0B5B891
names: Cofactor
names: Subunit
messages: Binds 4 [4Fe-4S] clusters per subunit.
messages: Heterodimer of a large and a small subunit.

345632:GPICK RS00155
gene id: 345632:GPICK_RS00155
uniprot id: A0A0B5B664
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15910
gene id: 345632:GPICK_RS15910
uniprot id: A0A0B5BKR2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08390
gene id: 345632:GPICK_RS08390
uniprot id: A0A0B5BFT0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

345632:GPICK RS13960
gene id: 345632:GPICK_RS13960
uniprot id: A0A0B5BGK6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

345632:GPICK RS16060
gene id: 345632:GPICK_RS16060
uniprot id: A0A0B5BKT5
names: Similarity
messages: Belongs to the pirin family.

345632:GPICK RS16470
gene id: 345632:GPICK_RS16470
uniprot id: A0A0B5BHV6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS01750
gene id: 345632:GPICK_RS01750
uniprot id: A0A0B5B6U4
names: Similarity
messages: Belongs to the UPF0178 family.

345632:GPICK RS04890
gene id: 345632:GPICK_RS04890
uniprot id: A0A0B5B8A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

345632:GPICK RS14060
gene id: 345632:GPICK_RS14060
uniprot id: A0A0B5BC82
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

345632:GPICK RS07885
gene id: 345632:GPICK_RS07885
uniprot id: A0A0B5BFH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

345632:GPICK RS14455
gene id: 345632:GPICK_RS14455
uniprot id: A0A0B5BLL4
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

345632:GPICK RS02080
gene id: 345632:GPICK_RS02080
uniprot id: A0A0B5BBI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

345632:GPICK RS02205
gene id: 345632:GPICK_RS02205
uniprot id: A0A0B5BE72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS09515
gene id: 345632:GPICK_RS09515
uniprot id: A0A0B5BA11
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

345632:GPICK RS07895
gene id: 345632:GPICK_RS07895
uniprot id: A0A0B5B9M3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

345632:GPICK RS02465
gene id: 345632:GPICK_RS02465
uniprot id: A0A0B5B7A1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

345632:GPICK RS08135
gene id: 345632:GPICK_RS08135
uniprot id: A0A0B5B9T5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

345632:GPICK RS03320
gene id: 345632:GPICK_RS03320
uniprot id: A0A0B5B7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

345632:GPICK RS13070
gene id: 345632:GPICK_RS13070
uniprot id: A0A0B5BCC2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS11905
gene id: 345632:GPICK_RS11905
uniprot id: A0A0B5BFP3
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS10555
gene id: 345632:GPICK_RS10555
uniprot id: A0A0B5BAZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

345632:GPICK RS11805
gene id: 345632:GPICK_RS11805
uniprot id: A0A0B5BIS1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS05390
gene id: 345632:GPICK_RS05390
uniprot id: A0A0B5BEC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS07310
gene id: 345632:GPICK_RS07310
uniprot id: A0A0B5B8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

345632:GPICK RS13625
gene id: 345632:GPICK_RS13625
uniprot id: A0A0B5BIA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

345632:GPICK RS12240
gene id: 345632:GPICK_RS12240
uniprot id: A0A0B5BFV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

345632:GPICK RS04235
gene id: 345632:GPICK_RS04235
uniprot id: A0A0B5B7Z3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08935
gene id: 345632:GPICK_RS08935
uniprot id: A0A0B5BG13
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS07275
gene id: 345632:GPICK_RS07275
uniprot id: A0A0B5BDH8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

345632:GPICK RS14670
gene id: 345632:GPICK_RS14670
uniprot id: A0A0B5BD90
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

345632:GPICK RS02680
gene id: 345632:GPICK_RS02680
uniprot id: A0A0B5B7A3
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

345632:GPICK RS06295
gene id: 345632:GPICK_RS06295
uniprot id: A0A0B5BES4
names: Similarity
messages: Belongs to the ros/MucR family.

345632:GPICK RS10780
gene id: 345632:GPICK_RS10780
uniprot id: A0A0B5BIA1
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS03440
gene id: 345632:GPICK_RS03440
uniprot id: A0A0B5BBZ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

345632:GPICK RS00845
gene id: 345632:GPICK_RS00845
uniprot id: A0A0B5B6G3
names: Similarity
messages: Belongs to the GSP L family.

345632:GPICK RS14500
gene id: 345632:GPICK_RS14500
uniprot id: A0A0B5BD58
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

345632:GPICK RS15035
gene id: 345632:GPICK_RS15035
uniprot id: A0A0B5BJ54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

345632:GPICK RS04560
gene id: 345632:GPICK_RS04560
uniprot id: A0A0B5BF87
names: Similarity
messages: Belongs to the AOR/FOR family.

345632:GPICK RS02185
gene id: 345632:GPICK_RS02185
uniprot id: A0A0B5B741
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

345632:GPICK RS08930
gene id: 345632:GPICK_RS08930
uniprot id: A0A0B5BE83
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS05130
gene id: 345632:GPICK_RS05130
uniprot id: A0A0B5B8F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

345632:GPICK RS13985
gene id: 345632:GPICK_RS13985
uniprot id: A0A0B5BJQ7
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03220
gene id: 345632:GPICK_RS03220
uniprot id: A0A0B5B7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

345632:GPICK RS02725
gene id: 345632:GPICK_RS02725
uniprot id: A0A0B5BD03
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS00875
gene id: 345632:GPICK_RS00875
uniprot id: A0A0B5B6G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Cell membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

345632:GPICK RS07135
gene id: 345632:GPICK_RS07135
uniprot id: A0A0B5BDG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

345632:GPICK RS00335
gene id: 345632:GPICK_RS00335
uniprot id: A0A0B5BD56
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

345632:GPICK RS07875
gene id: 345632:GPICK_RS07875
uniprot id: A0A0B5B968
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

345632:GPICK RS07890
gene id: 345632:GPICK_RS07890
uniprot id: A0A0B5BGV8
names: Similarity
messages: Belongs to the peptidase M16 family.

345632:GPICK RS16400
gene id: 345632:GPICK_RS16400
uniprot id: A0A0B5BE38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

345632:GPICK RS15285
gene id: 345632:GPICK_RS15285
uniprot id: A0A0B5BH83
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

345632:GPICK RS14645
gene id: 345632:GPICK_RS14645
uniprot id: A0A0B5BD84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

345632:GPICK RS17885
gene id: 345632:GPICK_RS17885
uniprot id: A0A0B5BCG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

345632:GPICK RS06800
gene id: 345632:GPICK_RS06800
uniprot id: A0A0B5B6I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

345632:GPICK RS07305
gene id: 345632:GPICK_RS07305
uniprot id: A0A0B5B9E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

345632:GPICK RS16425
gene id: 345632:GPICK_RS16425
uniprot id: A0A0B5BE44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

345632:GPICK RS03310
gene id: 345632:GPICK_RS03310
uniprot id: A0A0B5BBX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

345632:GPICK RS04710
gene id: 345632:GPICK_RS04710
uniprot id: A0A0B5B823
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

345632:GPICK RS15360
gene id: 345632:GPICK_RS15360
uniprot id: A0A0B5BDK6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS12320
gene id: 345632:GPICK_RS12320
uniprot id: A0A0B5BB83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

345632:GPICK RS10660
gene id: 345632:GPICK_RS10660
uniprot id: A0A0B5BB18
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

345632:GPICK RS11515
gene id: 345632:GPICK_RS11515
uniprot id: A0A0B5BFI9
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

345632:GPICK RS10460
gene id: 345632:GPICK_RS10460
uniprot id: A0A0B5BI45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

345632:GPICK RS02345
gene id: 345632:GPICK_RS02345
uniprot id: A0A0B5BCV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

345632:GPICK RS13940
gene id: 345632:GPICK_RS13940
uniprot id: A0A0B5BIH2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

345632:GPICK RS09910
gene id: 345632:GPICK_RS09910
uniprot id: A0A0B5BGI8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS06485
gene id: 345632:GPICK_RS06485
uniprot id: A0A0B5BD77
names: Similarity
messages: Belongs to the MEMO1 family.

345632:GPICK RS01715
gene id: 345632:GPICK_RS01715
uniprot id: A0A0B5B6T8
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS09465
gene id: 345632:GPICK_RS09465
uniprot id: A0A0B5BEG0
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

345632:GPICK RS11285
gene id: 345632:GPICK_RS11285
uniprot id: A0A0B5BFG3
names: Similarity
messages: Belongs to the acylphosphatase family.

345632:GPICK RS02195
gene id: 345632:GPICK_RS02195
uniprot id: A0A0B5BBL2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

345632:GPICK RS10020
gene id: 345632:GPICK_RS10020
uniprot id: A0A0B5BAA8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

345632:GPICK RS10330
gene id: 345632:GPICK_RS10330
uniprot id: A0A0B5BAF0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS03360
gene id: 345632:GPICK_RS03360
uniprot id: A0A0B5BBX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

345632:GPICK RS08340
gene id: 345632:GPICK_RS08340
uniprot id: A0A0B5BH61
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

345632:GPICK RS15470
gene id: 345632:GPICK_RS15470
uniprot id: A0A0B5BCX2
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

345632:GPICK RS06150
gene id: 345632:GPICK_RS06150
uniprot id: A0A0B5B8W8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

345632:GPICK RS06005
gene id: 345632:GPICK_RS06005
uniprot id: A0A0B5BEL6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

345632:GPICK RS10300
gene id: 345632:GPICK_RS10300
uniprot id: A0A0B5BAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS03495
gene id: 345632:GPICK_RS03495
uniprot id: A0A0B5BC09
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS12030
gene id: 345632:GPICK_RS12030
uniprot id: A0A0B5BHN1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS02265
gene id: 345632:GPICK_RS02265
uniprot id: A0A0B5B749
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

345632:GPICK RS13900
gene id: 345632:GPICK_RS13900
uniprot id: A0A0B5BC47
names: Similarity
messages: Belongs to the DEAD box helicase family.

345632:GPICK RS17285
gene id: 345632:GPICK_RS17285
uniprot id: A0A0B5B8Z0
names: Similarity
messages: Belongs to the intimin/invasin family.

345632:GPICK RS14770
gene id: 345632:GPICK_RS14770
uniprot id: A0A0B5BK62
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

345632:GPICK RS00760
gene id: 345632:GPICK_RS00760
uniprot id: A0A0B5B6D5
names: Similarity
messages: Belongs to the HupF/HypC family.

345632:GPICK RS13150
gene id: 345632:GPICK_RS13150
uniprot id: A0A0B5BI46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

345632:GPICK RS06000
gene id: 345632:GPICK_RS06000
uniprot id: A0A0B5BEG7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

345632:GPICK RS04835
gene id: 345632:GPICK_RS04835
uniprot id: A0A0B5B834
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

345632:GPICK RS15195
gene id: 345632:GPICK_RS15195
uniprot id: A0A0B5BKD8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.
messages: Periplasm

345632:GPICK RS14365
gene id: 345632:GPICK_RS14365
uniprot id: A0A0B5BIT9
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

345632:GPICK RS12090
gene id: 345632:GPICK_RS12090
uniprot id: A0A0B5BBU3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

345632:GPICK RS06135
gene id: 345632:GPICK_RS06135
uniprot id: A0A0B5BEP2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS12565
gene id: 345632:GPICK_RS12565
uniprot id: A0A0B5BEP8
names: Similarity
messages: Belongs to the DprA/Smf family.

345632:GPICK RS02655
gene id: 345632:GPICK_RS02655
uniprot id: A0A0B5B799
names: Similarity
messages: Belongs to the CobH/CbiC family.

345632:GPICK RS13170
gene id: 345632:GPICK_RS13170
uniprot id: A0A0B5BGA6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

345632:GPICK RS07085
gene id: 345632:GPICK_RS07085
uniprot id: A0A0B5B8X1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

345632:GPICK RS08080
gene id: 345632:GPICK_RS08080
uniprot id: A0A0B5BH05
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

345632:GPICK RS08285
gene id: 345632:GPICK_RS08285
uniprot id: A0A0B5B9V2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

345632:GPICK RS05275
gene id: 345632:GPICK_RS05275
uniprot id: A0A0B5BCQ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

345632:GPICK RS14525
gene id: 345632:GPICK_RS14525
uniprot id: A0A0B5BD63
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

345632:GPICK RS15365
gene id: 345632:GPICK_RS15365
uniprot id: A0A0B5BCV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS03960
gene id: 345632:GPICK_RS03960
uniprot id: A0A0B5B7T7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

345632:GPICK RS03840
gene id: 345632:GPICK_RS03840
uniprot id: A0A0B5BC49
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

345632:GPICK RS14740
gene id: 345632:GPICK_RS14740
uniprot id: A0A0B5BJ01
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

345632:GPICK RS12710
gene id: 345632:GPICK_RS12710
uniprot id: A0A0B5BC56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

345632:GPICK RS05955
gene id: 345632:GPICK_RS05955
uniprot id: A0A0B5BFX8
names: Similarity
messages: Belongs to the disproportionating enzyme family.

345632:GPICK RS08410
gene id: 345632:GPICK_RS08410
uniprot id: A0A0B5BE21
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS07965
gene id: 345632:GPICK_RS07965
uniprot id: A0A0B5BGX7
names: Similarity
messages: Belongs to the Nth/MutY family.

345632:GPICK RS01860
gene id: 345632:GPICK_RS01860
uniprot id: A0A0B5B6W8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

345632:GPICK RS05155
gene id: 345632:GPICK_RS05155
uniprot id: A0A0B5B8G3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

345632:GPICK RS01045
gene id: 345632:GPICK_RS01045
uniprot id: A0A0B5B6I6
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

345632:GPICK RS01365
gene id: 345632:GPICK_RS01365
uniprot id: A0A0B5BDP9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

345632:GPICK RS00015
gene id: 345632:GPICK_RS00015
uniprot id: A0A0B5BE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

345632:GPICK RS07265
gene id: 345632:GPICK_RS07265
uniprot id: A0A0B5B9E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

345632:GPICK RS13360
gene id: 345632:GPICK_RS13360
uniprot id: A0A0B5BCH8
names: Similarity
messages: Belongs to the GARS family.

345632:GPICK RS08825
gene id: 345632:GPICK_RS08825
uniprot id: A0A0B5BA33
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

345632:GPICK RS03925
gene id: 345632:GPICK_RS03925
uniprot id: A0A0B5BDL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

345632:GPICK RS07640
gene id: 345632:GPICK_RS07640
uniprot id: A0A0B5BGR3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS03280
gene id: 345632:GPICK_RS03280
uniprot id: A0A0B5B7L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

345632:GPICK RS05850
gene id: 345632:GPICK_RS05850
uniprot id: A0A0B5BCY5
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

345632:GPICK RS07335
gene id: 345632:GPICK_RS07335
uniprot id: A0A0B5B9E8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

345632:GPICK RS12055
gene id: 345632:GPICK_RS12055
uniprot id: A0A0B5BHN6
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

345632:GPICK RS08125
gene id: 345632:GPICK_RS08125
uniprot id: A0A0B5BFL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

345632:GPICK RS09595
gene id: 345632:GPICK_RS09595
uniprot id: A0A0B5BA27
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

345632:GPICK RS10180
gene id: 345632:GPICK_RS10180
uniprot id: A0A0B5BHZ4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

345632:GPICK RS01105
gene id: 345632:GPICK_RS01105
uniprot id: A0A0B5BB38
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

345632:GPICK RS14375
gene id: 345632:GPICK_RS14375
uniprot id: A0A0B5BD36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

345632:GPICK RS13255
gene id: 345632:GPICK_RS13255
uniprot id: A0A0B5BCF3
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

345632:GPICK RS15455
gene id: 345632:GPICK_RS15455
uniprot id: A0A0B5BJA2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03315
gene id: 345632:GPICK_RS03315
uniprot id: A0A0B5BDB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

345632:GPICK RS16315
gene id: 345632:GPICK_RS16315
uniprot id: A0A0B5BE20
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

345632:GPICK RS10600
gene id: 345632:GPICK_RS10600
uniprot id: A0A0B5BI70
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

345632:GPICK RS13055
gene id: 345632:GPICK_RS13055
uniprot id: A0A0B5BG96
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS06200
gene id: 345632:GPICK_RS06200
uniprot id: A0A0B5B8X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

345632:GPICK RS06555
gene id: 345632:GPICK_RS06555
uniprot id: A0A0B5BG94
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

345632:GPICK RS10880
gene id: 345632:GPICK_RS10880
uniprot id: A0A0B5BF63
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

345632:GPICK RS10520
gene id: 345632:GPICK_RS10520
uniprot id: A0A0B5BAY6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS03610
gene id: 345632:GPICK_RS03610
uniprot id: A0A0B5B7S7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS01445
gene id: 345632:GPICK_RS01445
uniprot id: A0A0B5BCB5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

345632:GPICK RS08350
gene id: 345632:GPICK_RS08350
uniprot id: A0A0B5B9W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

345632:GPICK RS00775
gene id: 345632:GPICK_RS00775
uniprot id: A0A0B5BC27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS06410
gene id: 345632:GPICK_RS06410
uniprot id: A0A0B5BG67
names: Similarity
messages: Belongs to the polysaccharide synthase family.

345632:GPICK RS16260
gene id: 345632:GPICK_RS16260
uniprot id: A0A0B5BHR6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS00455
gene id: 345632:GPICK_RS00455
uniprot id: A0A0B5BAR3
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

345632:GPICK RS02175
gene id: 345632:GPICK_RS02175
uniprot id: A0A0B5BCS8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS03675
gene id: 345632:GPICK_RS03675
uniprot id: A0A0B5BC35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

345632:GPICK RS15060
gene id: 345632:GPICK_RS15060
uniprot id: A0A0B5BH49
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

345632:GPICK RS10865
gene id: 345632:GPICK_RS10865
uniprot id: A0A0B5BIB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

345632:GPICK RS16340
gene id: 345632:GPICK_RS16340
uniprot id: A0A0B5BKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

345632:GPICK RS00450
gene id: 345632:GPICK_RS00450
uniprot id: A0A0B5B697
names: Similarity
messages: Belongs to the glutamate synthase family.

345632:GPICK RS14065
gene id: 345632:GPICK_RS14065
uniprot id: A0A0B5BGM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

345632:GPICK RS01470
gene id: 345632:GPICK_RS01470
uniprot id: A0A0B5BCB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

345632:GPICK RS04735
gene id: 345632:GPICK_RS04735
uniprot id: A0A0B5BFB5
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

345632:GPICK RS04145
gene id: 345632:GPICK_RS04145
uniprot id: A0A0B5BDQ5
names: Similarity
messages: Belongs to the LOG family.

345632:GPICK RS00365
gene id: 345632:GPICK_RS00365
uniprot id: A0A0B5B663
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

345632:GPICK RS14220
gene id: 345632:GPICK_RS14220
uniprot id: A0A0B5BCE4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

345632:GPICK RS12085
gene id: 345632:GPICK_RS12085
uniprot id: A0A0B5BIW4
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03255
gene id: 345632:GPICK_RS03255
uniprot id: A0A0B5BBW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

345632:GPICK RS08765
gene id: 345632:GPICK_RS08765
uniprot id: A0A0B5B9P2
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

345632:GPICK RS04690
gene id: 345632:GPICK_RS04690
uniprot id: A0A0B5BCF7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

345632:GPICK RS14675
gene id: 345632:GPICK_RS14675
uniprot id: A0A0B5BCK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

345632:GPICK RS00595
gene id: 345632:GPICK_RS00595
uniprot id: A0A0B5B6B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

345632:GPICK RS06760
gene id: 345632:GPICK_RS06760
uniprot id: A0A0B5B966
names: Similarity
messages: Belongs to the HdrA family.

345632:GPICK RS07140
gene id: 345632:GPICK_RS07140
uniprot id: A0A0B5BF54
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

345632:GPICK RS01005
gene id: 345632:GPICK_RS01005
uniprot id: A0A0B5B6I0
names: Similarity
names: Subunit
messages: Belongs to the CmpA/NrtA family.
messages: Heterodimer of a large and a small subunit.

345632:GPICK RS00990
gene id: 345632:GPICK_RS00990
uniprot id: A0A0B5BGE6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

345632:GPICK RS12550
gene id: 345632:GPICK_RS12550
uniprot id: A0A0B5BBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

345632:GPICK RS10355
gene id: 345632:GPICK_RS10355
uniprot id: A0A0B5BAF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

345632:GPICK RS02220
gene id: 345632:GPICK_RS02220
uniprot id: A0A0B5BBL7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

345632:GPICK RS08970
gene id: 345632:GPICK_RS08970
uniprot id: A0A0B5BG18
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

345632:GPICK RS03420
gene id: 345632:GPICK_RS03420
uniprot id: A0A0B5BDD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

345632:GPICK RS10870
gene id: 345632:GPICK_RS10870
uniprot id: A0A0B5BB58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

345632:GPICK RS01480
gene id: 345632:GPICK_RS01480
uniprot id: A0A0B5B6P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

345632:GPICK RS08430
gene id: 345632:GPICK_RS08430
uniprot id: A0A0B5B9K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

345632:GPICK RS00225
gene id: 345632:GPICK_RS00225
uniprot id: A0A0B5BD32
names: Similarity
messages: Belongs to the peptidase M16 family.

345632:GPICK RS05320
gene id: 345632:GPICK_RS05320
uniprot id: A0A0B5B8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

345632:GPICK RS12330
gene id: 345632:GPICK_RS12330
uniprot id: A0A0B5BIE3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

345632:GPICK RS06450
gene id: 345632:GPICK_RS06450
uniprot id: A0A0B5BD73
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

345632:GPICK RS13905
gene id: 345632:GPICK_RS13905
uniprot id: A0A0B5BGJ4
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS16320
gene id: 345632:GPICK_RS16320
uniprot id: A0A0B5BDD3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

345632:GPICK RS10710
gene id: 345632:GPICK_RS10710
uniprot id: A0A0B5BGX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

345632:GPICK RS01830
gene id: 345632:GPICK_RS01830
uniprot id: A0A0B5BDY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

345632:GPICK RS13710
gene id: 345632:GPICK_RS13710
uniprot id: A0A0B5BGG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS09470
gene id: 345632:GPICK_RS09470
uniprot id: A0A0B5BAW2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

345632:GPICK RS10485
gene id: 345632:GPICK_RS10485
uniprot id: A0A0B5BI49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

345632:GPICK RS04980
gene id: 345632:GPICK_RS04980
uniprot id: A0A0B5BCJ6
names: Similarity
messages: Belongs to the FemABX family.

345632:GPICK RS03295
gene id: 345632:GPICK_RS03295
uniprot id: A0A0B5BEN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

345632:GPICK RS14140
gene id: 345632:GPICK_RS14140
uniprot id: A0A0B5BCZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

345632:GPICK RS04045
gene id: 345632:GPICK_RS04045
uniprot id: A0A0B5BDP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

345632:GPICK RS09485
gene id: 345632:GPICK_RS09485
uniprot id: A0A0B5BA03
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS10455
gene id: 345632:GPICK_RS10455
uniprot id: A0A0B5BGR9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

345632:GPICK RS13035
gene id: 345632:GPICK_RS13035
uniprot id: A0A0B5BI33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

345632:GPICK RS06095
gene id: 345632:GPICK_RS06095
uniprot id: A0A0B5B8I3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

345632:GPICK RS15250
gene id: 345632:GPICK_RS15250
uniprot id: A0A0B5BDI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

345632:GPICK RS11950
gene id: 345632:GPICK_RS11950
uniprot id: A0A0B5BBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

345632:GPICK RS10770
gene id: 345632:GPICK_RS10770
uniprot id: A0A0B5BF42
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

345632:GPICK RS07650
gene id: 345632:GPICK_RS07650
uniprot id: A0A0B5B930
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

345632:GPICK RS14955
gene id: 345632:GPICK_RS14955
uniprot id: A0A0B5BDE2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

345632:GPICK RS13790
gene id: 345632:GPICK_RS13790
uniprot id: A0A0B5BCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS04205
gene id: 345632:GPICK_RS04205
uniprot id: A0A0B5BF27
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS15225
gene id: 345632:GPICK_RS15225
uniprot id: A0A0B5BDI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

345632:GPICK RS14635
gene id: 345632:GPICK_RS14635
uniprot id: A0A0B5BIY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

345632:GPICK RS08605
gene id: 345632:GPICK_RS08605
uniprot id: A0A0B5BHA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

345632:GPICK RS08050
gene id: 345632:GPICK_RS08050
uniprot id: A0A0B5BGZ6
names: Similarity
messages: Belongs to the threonine synthase family.

345632:GPICK RS00815
gene id: 345632:GPICK_RS00815
uniprot id: A0A0B5B6E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS02605
gene id: 345632:GPICK_RS02605
uniprot id: A0A0B5B7C0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

345632:GPICK RS07225
gene id: 345632:GPICK_RS07225
uniprot id: A0A0B5BF64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane

345632:GPICK RS00300
gene id: 345632:GPICK_RS00300
uniprot id: A0A0B5BAN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

345632:GPICK RS10495
gene id: 345632:GPICK_RS10495
uniprot id: A0A0B5BAG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

345632:GPICK RS08680
gene id: 345632:GPICK_RS08680
uniprot id: A0A0B5BFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

345632:GPICK RS04505
gene id: 345632:GPICK_RS04505
uniprot id: A0A0B5BF77
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

345632:GPICK RS14760
gene id: 345632:GPICK_RS14760
uniprot id: A0A0B5BH14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

345632:GPICK RS14845
gene id: 345632:GPICK_RS14845
uniprot id: A0A0B5BK77
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

345632:GPICK RS02610
gene id: 345632:GPICK_RS02610
uniprot id: A0A0B5BBP8
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

345632:GPICK RS07360
gene id: 345632:GPICK_RS07360
uniprot id: A0A0B5B9F3
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS02270
gene id: 345632:GPICK_RS02270
uniprot id: A0A0B5B769
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

345632:GPICK RS08010
gene id: 345632:GPICK_RS08010
uniprot id: A0A0B5BDS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

345632:GPICK RS06970
gene id: 345632:GPICK_RS06970
uniprot id: A0A0B5BF31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS02215
gene id: 345632:GPICK_RS02215
uniprot id: A0A0B5B763
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

345632:GPICK RS06380
gene id: 345632:GPICK_RS06380
uniprot id: A0A0B5BG62
names: Similarity
messages: Belongs to the polysaccharide synthase family.

345632:GPICK RS08500
gene id: 345632:GPICK_RS08500
uniprot id: A0A0B5BE31
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

345632:GPICK RS15495
gene id: 345632:GPICK_RS15495
uniprot id: A0A0B5BCX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

345632:GPICK RS10500
gene id: 345632:GPICK_RS10500
uniprot id: A0A0B5BF02
names: Similarity
messages: Belongs to the Skp family.

345632:GPICK RS10515
gene id: 345632:GPICK_RS10515
uniprot id: A0A0B5BI54
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08595
gene id: 345632:GPICK_RS08595
uniprot id: A0A0B5BE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

345632:GPICK RS05325
gene id: 345632:GPICK_RS05325
uniprot id: A0A0B5B889
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

345632:GPICK RS14040
gene id: 345632:GPICK_RS14040
uniprot id: A0A0B5BIJ4
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

345632:GPICK RS10650
gene id: 345632:GPICK_RS10650
uniprot id: A0A0B5BGW1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS10850
gene id: 345632:GPICK_RS10850
uniprot id: A0A0B5BAM0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

345632:GPICK RS11080
gene id: 345632:GPICK_RS11080
uniprot id: A0A0B5BIF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

345632:GPICK RS02425
gene id: 345632:GPICK_RS02425
uniprot id: A0A0B5BEA7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

345632:GPICK RS14550
gene id: 345632:GPICK_RS14550
uniprot id: A0A0B5BD68
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

345632:GPICK RS03735
gene id: 345632:GPICK_RS03735
uniprot id: A0A0B5BEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

345632:GPICK RS14840
gene id: 345632:GPICK_RS14840
uniprot id: A0A0B5BJ22
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

345632:GPICK RS02325
gene id: 345632:GPICK_RS02325
uniprot id: A0A0B5BE89
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15295
gene id: 345632:GPICK_RS15295
uniprot id: A0A0B5BJ81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS06180
gene id: 345632:GPICK_RS06180
uniprot id: A0A0B5B8J5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

345632:GPICK RS01430
gene id: 345632:GPICK_RS01430
uniprot id: A0A0B5B6N9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

345632:GPICK RS15680
gene id: 345632:GPICK_RS15680
uniprot id: A0A0B5BKM4
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS11010
gene id: 345632:GPICK_RS11010
uniprot id: A0A0B5BLH2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

345632:GPICK RS14170
gene id: 345632:GPICK_RS14170
uniprot id: A0A0B5BCD7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

345632:GPICK RS08170
gene id: 345632:GPICK_RS08170
uniprot id: A0A0B5B9T6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS09320
gene id: 345632:GPICK_RS09320
uniprot id: A0A0B5B9X1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

345632:GPICK RS08380
gene id: 345632:GPICK_RS08380
uniprot id: A0A0B5B9J2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

345632:GPICK RS13260
gene id: 345632:GPICK_RS13260
uniprot id: A0A0B5BBQ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

345632:GPICK RS03930
gene id: 345632:GPICK_RS03930
uniprot id: A0A0B5BEY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

345632:GPICK RS13365
gene id: 345632:GPICK_RS13365
uniprot id: A0A0B5BBS9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

345632:GPICK RS04805
gene id: 345632:GPICK_RS04805
uniprot id: A0A0B5B832
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS16205
gene id: 345632:GPICK_RS16205
uniprot id: A0A0B5BHQ6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

345632:GPICK RS11655
gene id: 345632:GPICK_RS11655
uniprot id: A0A0B5BAY1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

345632:GPICK RS01520
gene id: 345632:GPICK_RS01520
uniprot id: A0A0B5BCC6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

345632:GPICK RS00495
gene id: 345632:GPICK_RS00495
uniprot id: A0A0B5BD92
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

345632:GPICK RS08485
gene id: 345632:GPICK_RS08485
uniprot id: A0A0B5BH82
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

345632:GPICK RS15460
gene id: 345632:GPICK_RS15460
uniprot id: A0A0B5BKI5
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

345632:GPICK RS08735
gene id: 345632:GPICK_RS08735
uniprot id: A0A0B5BE59
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

345632:GPICK RS10405
gene id: 345632:GPICK_RS10405
uniprot id: A0A0B5BAF9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS05810
gene id: 345632:GPICK_RS05810
uniprot id: A0A0B5B8F4
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

345632:GPICK RS02150
gene id: 345632:GPICK_RS02150
uniprot id: A0A0B5BE64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

345632:GPICK RS16045
gene id: 345632:GPICK_RS16045
uniprot id: A0A0B5BHM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

345632:GPICK RS02340
gene id: 345632:GPICK_RS02340
uniprot id: A0A0B5BBM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

345632:GPICK RS05180
gene id: 345632:GPICK_RS05180
uniprot id: A0A0B5B8G9
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

345632:GPICK RS04685
gene id: 345632:GPICK_RS04685
uniprot id: A0A0B5B822
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

345632:GPICK RS15265
gene id: 345632:GPICK_RS15265
uniprot id: A0A0B5BJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS05040
gene id: 345632:GPICK_RS05040
uniprot id: A0A0B5BCK5
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

345632:GPICK RS14825
gene id: 345632:GPICK_RS14825
uniprot id: A0A0B5BDB9
names: Similarity
messages: Belongs to the thioredoxin family.

345632:GPICK RS06465
gene id: 345632:GPICK_RS06465
uniprot id: A0A0B5B929
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS13355
gene id: 345632:GPICK_RS13355
uniprot id: A0A0B5BJF5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

345632:GPICK RS12275
gene id: 345632:GPICK_RS12275
uniprot id: A0A0B5BFV8
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

345632:GPICK RS11110
gene id: 345632:GPICK_RS11110
uniprot id: A0A0B5BII0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

345632:GPICK RS02955
gene id: 345632:GPICK_RS02955
uniprot id: A0A0B5B7E3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15870
gene id: 345632:GPICK_RS15870
uniprot id: A0A0B5BJH3
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

345632:GPICK RS09400
gene id: 345632:GPICK_RS09400
uniprot id: A0A0B5BEF3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

345632:GPICK RS00100
gene id: 345632:GPICK_RS00100
uniprot id: A0A0B5BAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

345632:GPICK RS13915
gene id: 345632:GPICK_RS13915
uniprot id: A0A0B5BJP3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS08155
gene id: 345632:GPICK_RS08155
uniprot id: A0A0B5BFP2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

345632:GPICK RS01735
gene id: 345632:GPICK_RS01735
uniprot id: A0A0B5BCG8
names: Similarity
messages: Belongs to the cytochrome c-552 family.

345632:GPICK RS15830
gene id: 345632:GPICK_RS15830
uniprot id: A0A0B5BD43
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS13855
gene id: 345632:GPICK_RS13855
uniprot id: A0A0B5BGI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

345632:GPICK RS01350
gene id: 345632:GPICK_RS01350
uniprot id: A0A0B5B6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

345632:GPICK RS11250
gene id: 345632:GPICK_RS11250
uniprot id: A0A0B5BBE7
names: Similarity
messages: Belongs to the peptidase U62 family.

345632:GPICK RS13155
gene id: 345632:GPICK_RS13155
uniprot id: A0A0B5BJC6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

345632:GPICK RS14400
gene id: 345632:GPICK_RS14400
uniprot id: A0A0B5BD41
names: Similarity
messages: Belongs to the GcvT family.

345632:GPICK RS10950
gene id: 345632:GPICK_RS10950
uniprot id: A0A0B5BAP3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

345632:GPICK RS03290
gene id: 345632:GPICK_RS03290
uniprot id: A0A0B5BDA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

345632:GPICK RS02335
gene id: 345632:GPICK_RS02335
uniprot id: A0A0B5B778
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS13520
gene id: 345632:GPICK_RS13520
uniprot id: A0A0B5BI94
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS05585
gene id: 345632:GPICK_RS05585
uniprot id: A0A0B5BFT5
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

345632:GPICK RS02645
gene id: 345632:GPICK_RS02645
uniprot id: A0A0B5BCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

345632:GPICK RS01855
gene id: 345632:GPICK_RS01855
uniprot id: A0A0B5BDY3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

345632:GPICK RS06205
gene id: 345632:GPICK_RS06205
uniprot id: A0A0B5B8J9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

345632:GPICK RS05285
gene id: 345632:GPICK_RS05285
uniprot id: A0A0B5BFN3
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

345632:GPICK RS04795
gene id: 345632:GPICK_RS04795
uniprot id: A0A0B5BFC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

345632:GPICK RS14230
gene id: 345632:GPICK_RS14230
uniprot id: A0A0B5BGU0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

345632:GPICK RS03810
gene id: 345632:GPICK_RS03810
uniprot id: A0A0B5B7Q9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS05385
gene id: 345632:GPICK_RS05385
uniprot id: A0A0B5BCR8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

345632:GPICK RS04535
gene id: 345632:GPICK_RS04535
uniprot id: A0A0B5BF82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

345632:GPICK RS15730
gene id: 345632:GPICK_RS15730
uniprot id: A0A0B5BJE9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

345632:GPICK RS02375
gene id: 345632:GPICK_RS02375
uniprot id: A0A0B5BE97
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

345632:GPICK RS03470
gene id: 345632:GPICK_RS03470
uniprot id: A0A0B5BDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS08640
gene id: 345632:GPICK_RS08640
uniprot id: A0A0B5B9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

345632:GPICK RS04430
gene id: 345632:GPICK_RS04430
uniprot id: A0A0B5BL79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

345632:GPICK RS00520
gene id: 345632:GPICK_RS00520
uniprot id: A0A0B5BBX8
names: Similarity
messages: Belongs to the YjdM family.

345632:GPICK RS04780
gene id: 345632:GPICK_RS04780
uniprot id: A0A0B5B828
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

345632:GPICK RS05700
gene id: 345632:GPICK_RS05700
uniprot id: A0A0B5B8E4
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS04620
gene id: 345632:GPICK_RS04620
uniprot id: A0A0B5BF95
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

345632:GPICK RS14270
gene id: 345632:GPICK_RS14270
uniprot id: A0A0B5BD18
names: Similarity
messages: Belongs to the hemerythrin family.

345632:GPICK RS02225
gene id: 345632:GPICK_RS02225
uniprot id: A0A0B5BCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

345632:GPICK RS05770
gene id: 345632:GPICK_RS05770
uniprot id: A0A0B5B8R3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS09520
gene id: 345632:GPICK_RS09520
uniprot id: A0A0B5BEH0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

345632:GPICK RS05615
gene id: 345632:GPICK_RS05615
uniprot id: A0A0B5BEF8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

345632:GPICK RS15550
gene id: 345632:GPICK_RS15550
uniprot id: A0A0B5BCY9
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS10815
gene id: 345632:GPICK_RS10815
uniprot id: A0A0B5BIA7
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS09300
gene id: 345632:GPICK_RS09300
uniprot id: A0A0B5BED6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

345632:GPICK RS08630
gene id: 345632:GPICK_RS08630
uniprot id: A0A0B5BHA5
names: Similarity
messages: Belongs to the ribF family.

345632:GPICK RS10475
gene id: 345632:GPICK_RS10475
uniprot id: A0A0B5BEZ7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

345632:GPICK RS05985
gene id: 345632:GPICK_RS05985
uniprot id: A0A0B5B8T9
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

345632:GPICK RS08655
gene id: 345632:GPICK_RS08655
uniprot id: A0A0B5BFW8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

345632:GPICK RS03395
gene id: 345632:GPICK_RS03395
uniprot id: A0A0B5BEQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

345632:GPICK RS16450
gene id: 345632:GPICK_RS16450
uniprot id: A0A0B5BL05
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

345632:GPICK RS05620
gene id: 345632:GPICK_RS05620
uniprot id: A0A0B5BFT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

345632:GPICK RS15235
gene id: 345632:GPICK_RS15235
uniprot id: A0A0B5BH75
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

345632:GPICK RS14695
gene id: 345632:GPICK_RS14695
uniprot id: A0A0B5BK45
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

345632:GPICK RS12380
gene id: 345632:GPICK_RS12380
uniprot id: A0A0B5BB91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

345632:GPICK RS13930
gene id: 345632:GPICK_RS13930
uniprot id: A0A0B5BC54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

345632:GPICK RS14890
gene id: 345632:GPICK_RS14890
uniprot id: A0A0B5BH29
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

345632:GPICK RS03435
gene id: 345632:GPICK_RS03435
uniprot id: A0A0B5B7P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

345632:GPICK RS09890
gene id: 345632:GPICK_RS09890
uniprot id: A0A0B5BHU6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

345632:GPICK RS14160
gene id: 345632:GPICK_RS14160
uniprot id: A0A0B5BJX2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

345632:GPICK RS08400
gene id: 345632:GPICK_RS08400
uniprot id: A0A0B5B9W9
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

345632:GPICK RS05170
gene id: 345632:GPICK_RS05170
uniprot id: A0A0B5BE90
names: Similarity
messages: Belongs to the DnaA family.

345632:GPICK RS15430
gene id: 345632:GPICK_RS15430
uniprot id: A0A0B5BKI0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

345632:GPICK RS10610
gene id: 345632:GPICK_RS10610
uniprot id: A0A0B5BAI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS15835
gene id: 345632:GPICK_RS15835
uniprot id: A0A0B5BHI8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

345632:GPICK RS04350
gene id: 345632:GPICK_RS04350
uniprot id: A0A0B5BF50
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

345632:GPICK RS12610
gene id: 345632:GPICK_RS12610
uniprot id: A0A0B5BBC5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

345632:GPICK RS11725
gene id: 345632:GPICK_RS11725
uniprot id: A0A0B5BIQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

345632:GPICK RS09380
gene id: 345632:GPICK_RS09380
uniprot id: A0A0B5BG91
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

345632:GPICK RS05335
gene id: 345632:GPICK_RS05335
uniprot id: A0A0B5BEB8
names: Similarity
messages: Belongs to the peptidase S8 family.

345632:GPICK RS12280
gene id: 345632:GPICK_RS12280
uniprot id: A0A0B5BHS3
names: Similarity
messages: Belongs to the AAE transporter (TC 2.A.81) family.

345632:GPICK RS10170
gene id: 345632:GPICK_RS10170
uniprot id: A0A0B5BET5
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

345632:GPICK RS14750
gene id: 345632:GPICK_RS14750
uniprot id: A0A0B5BDA5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

345632:GPICK RS05255
gene id: 345632:GPICK_RS05255
uniprot id: A0A0B5BEA6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

345632:GPICK RS09555
gene id: 345632:GPICK_RS09555
uniprot id: A0A0B5BHP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

345632:GPICK RS07355
gene id: 345632:GPICK_RS07355
uniprot id: A0A0B5BGL8
names: Similarity
messages: Belongs to the Rieske iron-sulfur protein family.

345632:GPICK RS09560
gene id: 345632:GPICK_RS09560
uniprot id: A0A0B5BAG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

345632:GPICK RS03935
gene id: 345632:GPICK_RS03935
uniprot id: A0A0B5B7T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

345632:GPICK RS03215
gene id: 345632:GPICK_RS03215
uniprot id: A0A0B5BEM8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

345632:GPICK RS13680
gene id: 345632:GPICK_RS13680
uniprot id: A0A0B5BIC1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

345632:GPICK RS13545
gene id: 345632:GPICK_RS13545
uniprot id: A0A0B5BI99
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS02380
gene id: 345632:GPICK_RS02380
uniprot id: A0A0B5B762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell membrane
messages: Essential cell division protein.

345632:GPICK RS14700
gene id: 345632:GPICK_RS14700
uniprot id: A0A0B5BD95
names: Similarity
messages: Belongs to the UPF0234 family.

345632:GPICK RS16475
gene id: 345632:GPICK_RS16475
uniprot id: A0A0B5BJT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

345632:GPICK RS14470
gene id: 345632:GPICK_RS14470
uniprot id: A0A0B5BCH7
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

345632:GPICK RS02350
gene id: 345632:GPICK_RS02350
uniprot id: A0A0B5BE94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

345632:GPICK RS12870
gene id: 345632:GPICK_RS12870
uniprot id: A0A0B5BBH2
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

345632:GPICK RS11830
gene id: 345632:GPICK_RS11830
uniprot id: A0A0B5BHJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

345632:GPICK RS07235
gene id: 345632:GPICK_RS07235
uniprot id: A0A0B5B9D6
names: Similarity
messages: Belongs to the peptidase S41A family.

345632:GPICK RS12510
gene id: 345632:GPICK_RS12510
uniprot id: A0A0B5BHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

345632:GPICK RS09295
gene id: 345632:GPICK_RS09295
uniprot id: A0A0B5B9W6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS05375
gene id: 345632:GPICK_RS05375
uniprot id: A0A0B5B8K2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS05580
gene id: 345632:GPICK_RS05580
uniprot id: A0A0B5BEF4
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

345632:GPICK RS09565
gene id: 345632:GPICK_RS09565
uniprot id: A0A0B5BA21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

345632:GPICK RS08225
gene id: 345632:GPICK_RS08225
uniprot id: A0A0B5BH47
names: Similarity
messages: Belongs to the leucine-binding protein family.

345632:GPICK RS04680
gene id: 345632:GPICK_RS04680
uniprot id: A0A0B5B877
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

345632:GPICK RS12950
gene id: 345632:GPICK_RS12950
uniprot id: A0A0B5BBJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

345632:GPICK RS05540
gene id: 345632:GPICK_RS05540
uniprot id: A0A0B5B8C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

345632:GPICK RS03665
gene id: 345632:GPICK_RS03665
uniprot id: A0A0B5B7N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

345632:GPICK RS08835
gene id: 345632:GPICK_RS08835
uniprot id: A0A0B5BE71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

345632:GPICK RS02355
gene id: 345632:GPICK_RS02355
uniprot id: A0A0B5B759
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS12405
gene id: 345632:GPICK_RS12405
uniprot id: A0A0B5BBZ6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

345632:GPICK RS02320
gene id: 345632:GPICK_RS02320
uniprot id: A0A0B5BCV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

345632:GPICK RS03625
gene id: 345632:GPICK_RS03625
uniprot id: A0A0B5BL62
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

345632:GPICK RS16050
gene id: 345632:GPICK_RS16050
uniprot id: A0A0B5BJJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

345632:GPICK RS07015
gene id: 345632:GPICK_RS07015
uniprot id: A0A0B5BF35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS15965
gene id: 345632:GPICK_RS15965
uniprot id: A0A0B5BHK6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS08355
gene id: 345632:GPICK_RS08355
uniprot id: A0A0B5B9I7
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

345632:GPICK RS12105
gene id: 345632:GPICK_RS12105
uniprot id: A0A0B5BFT2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

345632:GPICK RS10090
gene id: 345632:GPICK_RS10090
uniprot id: A0A0B5BAC1
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

345632:GPICK RS14030
gene id: 345632:GPICK_RS14030
uniprot id: A0A0B5BC77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

345632:GPICK RS00320
gene id: 345632:GPICK_RS00320
uniprot id: A0A0B5B682
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00740
gene id: 345632:GPICK_RS00740
uniprot id: A0A0B5BAW5
names: Similarity
messages: Belongs to the pyruvate kinase family.

345632:GPICK RS01440
gene id: 345632:GPICK_RS01440
uniprot id: A0A0B5BB81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

345632:GPICK RS14565
gene id: 345632:GPICK_RS14565
uniprot id: A0A0B5BGY7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

345632:GPICK RS11540
gene id: 345632:GPICK_RS11540
uniprot id: A0A0B5BFJ3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

345632:GPICK RS09365
gene id: 345632:GPICK_RS09365
uniprot id: A0A0B5BAC2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

345632:GPICK RS09425
gene id: 345632:GPICK_RS09425
uniprot id: A0A0B5BEF6
names: Similarity
messages: Belongs to the AOR/FOR family.

345632:GPICK RS02675
gene id: 345632:GPICK_RS02675
uniprot id: A0A0B5BEE1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

345632:GPICK RS03330
gene id: 345632:GPICK_RS03330
uniprot id: A0A0B5B7M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

345632:GPICK RS01190
gene id: 345632:GPICK_RS01190
uniprot id: A0A0B5B6L0
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.

345632:GPICK RS02495
gene id: 345632:GPICK_RS02495
uniprot id: A0A0B5B7A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

345632:GPICK RS10535
gene id: 345632:GPICK_RS10535
uniprot id: A0A0B5BF07
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

345632:GPICK RS01415
gene id: 345632:GPICK_RS01415
uniprot id: A0A0B5BB77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

345632:GPICK RS13540
gene id: 345632:GPICK_RS13540
uniprot id: A0A0B5BGE5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS06540
gene id: 345632:GPICK_RS06540
uniprot id: A0A0B5B8P0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

345632:GPICK RS14530
gene id: 345632:GPICK_RS14530
uniprot id: A0A0B5BCI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

345632:GPICK RS01460
gene id: 345632:GPICK_RS01460
uniprot id: A0A0B5B6Q0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

345632:GPICK RS08040
gene id: 345632:GPICK_RS08040
uniprot id: A0A0B5BDS8
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

345632:GPICK RS04255
gene id: 345632:GPICK_RS04255
uniprot id: A0A0B5BF36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

345632:GPICK RS07840
gene id: 345632:GPICK_RS07840
uniprot id: A0A0B5B9L2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS02710
gene id: 345632:GPICK_RS02710
uniprot id: A0A0B5B7D5
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

345632:GPICK RS02315
gene id: 345632:GPICK_RS02315
uniprot id: A0A0B5BBM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

345632:GPICK RS02155
gene id: 345632:GPICK_RS02155
uniprot id: A0A0B5B739
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

345632:GPICK RS10570
gene id: 345632:GPICK_RS10570
uniprot id: A0A0B5BGU3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

345632:GPICK RS07950
gene id: 345632:GPICK_RS07950
uniprot id: A0A0B5B987
names: Similarity
messages: Belongs to the LacAB/RpiB family.

345632:GPICK RS05960
gene id: 345632:GPICK_RS05960
uniprot id: A0A0B5B8T5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

345632:GPICK RS15575
gene id: 345632:GPICK_RS15575
uniprot id: A0A0B5BDP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

345632:GPICK RS02875
gene id: 345632:GPICK_RS02875
uniprot id: A0A0B5BD33
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

345632:GPICK RS11965
gene id: 345632:GPICK_RS11965
uniprot id: A0A0B5BHM1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01450
gene id: 345632:GPICK_RS01450
uniprot id: A0A0B5BDR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

345632:GPICK RS04365
gene id: 345632:GPICK_RS04365
uniprot id: A0A0B5BCB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

345632:GPICK RS09195
gene id: 345632:GPICK_RS09195
uniprot id: A0A0B5BG55
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

345632:GPICK RS06500
gene id: 345632:GPICK_RS06500
uniprot id: A0A0B5B935
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

345632:GPICK RS09290
gene id: 345632:GPICK_RS09290
uniprot id: A0A0B5BAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

345632:GPICK RS09355
gene id: 345632:GPICK_RS09355
uniprot id: A0A0B5BG86
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

345632:GPICK RS07220
gene id: 345632:GPICK_RS07220
uniprot id: A0A0B5BDG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

345632:GPICK RS04500
gene id: 345632:GPICK_RS04500
uniprot id: A0A0B5BDV9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

345632:GPICK RS11845
gene id: 345632:GPICK_RS11845
uniprot id: A0A0B5BB11
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

345632:GPICK RS01910
gene id: 345632:GPICK_RS01910
uniprot id: A0A0B5B6Y0
names: Similarity
messages: Belongs to the VgrG protein family.

345632:GPICK RS09835
gene id: 345632:GPICK_RS09835
uniprot id: A0A0B5BHT6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

345632:GPICK RS11025
gene id: 345632:GPICK_RS11025
uniprot id: A0A0B5BH28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

345632:GPICK RS03340
gene id: 345632:GPICK_RS03340
uniprot id: A0A0B5BDB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

345632:GPICK RS10370
gene id: 345632:GPICK_RS10370
uniprot id: A0A0B5BI31
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

345632:GPICK RS15845
gene id: 345632:GPICK_RS15845
uniprot id: A0A0B5BKQ2
names: Similarity
messages: Belongs to the leucine-binding protein family.

345632:GPICK RS13945
gene id: 345632:GPICK_RS13945
uniprot id: A0A0B5BJP9
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS10920
gene id: 345632:GPICK_RS10920
uniprot id: A0A0B5BB70
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS09850
gene id: 345632:GPICK_RS09850
uniprot id: A0A0B5BEN0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

345632:GPICK RS01850
gene id: 345632:GPICK_RS01850
uniprot id: A0A0B5BCJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

345632:GPICK RS04170
gene id: 345632:GPICK_RS04170
uniprot id: A0A0B5BDR0
names: Similarity
messages: Belongs to the UPF0145 family.

345632:GPICK RS02825
gene id: 345632:GPICK_RS02825
uniprot id: A0A0B5BD22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

345632:GPICK RS00060
gene id: 345632:GPICK_RS00060
uniprot id: A0A0B5B656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS14390
gene id: 345632:GPICK_RS14390
uniprot id: A0A0B5BIU4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

345632:GPICK RS15245
gene id: 345632:GPICK_RS15245
uniprot id: A0A0B5BKE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS13560
gene id: 345632:GPICK_RS13560
uniprot id: A0A0B5BBX4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

345632:GPICK RS02130
gene id: 345632:GPICK_RS02130
uniprot id: A0A0B5B737
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

345632:GPICK RS05435
gene id: 345632:GPICK_RS05435
uniprot id: A0A0B5BCS7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

345632:GPICK RS10350
gene id: 345632:GPICK_RS10350
uniprot id: A0A0B5BAU8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

345632:GPICK RS11120
gene id: 345632:GPICK_RS11120
uniprot id: A0A0B5BAS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

345632:GPICK RS16160
gene id: 345632:GPICK_RS16160
uniprot id: A0A0B5BKV1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

345632:GPICK RS03690
gene id: 345632:GPICK_RS03690
uniprot id: A0A0B5B7P2
names: Similarity
messages: Belongs to the RecJ family.

345632:GPICK RS06110
gene id: 345632:GPICK_RS06110
uniprot id: A0A0B5BEN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

345632:GPICK RS03745
gene id: 345632:GPICK_RS03745
uniprot id: A0A0B5B7T5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

345632:GPICK RS10925
gene id: 345632:GPICK_RS10925
uniprot id: A0A0B5BAN8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01260
gene id: 345632:GPICK_RS01260
uniprot id: A0A0B5BB63
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

345632:GPICK RS14425
gene id: 345632:GPICK_RS14425
uniprot id: A0A0B5BK03
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08360
gene id: 345632:GPICK_RS08360
uniprot id: A0A0B5BE11
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

345632:GPICK RS14340
gene id: 345632:GPICK_RS14340
uniprot id: A0A0B5BIT4
names: Similarity
messages: Belongs to the UPF0111 family.

345632:GPICK RS15260
gene id: 345632:GPICK_RS15260
uniprot id: A0A0B5BH79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS15585
gene id: 345632:GPICK_RS15585
uniprot id: A0A0B5BHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

345632:GPICK RS16235
gene id: 345632:GPICK_RS16235
uniprot id: A0A0B5BJN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

345632:GPICK RS06285
gene id: 345632:GPICK_RS06285
uniprot id: A0A0B5B8L0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

345632:GPICK RS04140
gene id: 345632:GPICK_RS04140
uniprot id: A0A0B5BC85
names: Similarity
messages: Belongs to the SUI1 family.

345632:GPICK RS07100
gene id: 345632:GPICK_RS07100
uniprot id: A0A0B5BGI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

345632:GPICK RS06270
gene id: 345632:GPICK_RS06270
uniprot id: A0A0B5BER8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

345632:GPICK RS11005
gene id: 345632:GPICK_RS11005
uniprot id: A0A0B5BB82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

345632:GPICK RS05705
gene id: 345632:GPICK_RS05705
uniprot id: A0A0B5BI59
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08925
gene id: 345632:GPICK_RS08925
uniprot id: A0A0B5B9R9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

345632:GPICK RS13890
gene id: 345632:GPICK_RS13890
uniprot id: A0A0B5BJN7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

345632:GPICK RS10680
gene id: 345632:GPICK_RS10680
uniprot id: A0A0B5BGW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS01710
gene id: 345632:GPICK_RS01710
uniprot id: A0A0B5BDW1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

345632:GPICK RS04515
gene id: 345632:GPICK_RS04515
uniprot id: A0A0B5B849
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

345632:GPICK RS11935
gene id: 345632:GPICK_RS11935
uniprot id: A0A0B5BHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

345632:GPICK RS03550
gene id: 345632:GPICK_RS03550
uniprot id: A0A0B5B7R7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

345632:GPICK RS08320
gene id: 345632:GPICK_RS08320
uniprot id: A0A0B5B9V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

345632:GPICK RS12700
gene id: 345632:GPICK_RS12700
uniprot id: A0A0B5BHZ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

345632:GPICK RS11735
gene id: 345632:GPICK_RS11735
uniprot id: A0A0B5BAZ4
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

345632:GPICK RS08510
gene id: 345632:GPICK_RS08510
uniprot id: A0A0B5BH86
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS02240
gene id: 345632:GPICK_RS02240
uniprot id: A0A0B5B766
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

345632:GPICK RS00025
gene id: 345632:GPICK_RS00025
uniprot id: A0A0B5BAJ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

345632:GPICK RS14275
gene id: 345632:GPICK_RS14275
uniprot id: A0A0B5BCF1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS06250
gene id: 345632:GPICK_RS06250
uniprot id: A0A0B5BG42
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

345632:GPICK RS14095
gene id: 345632:GPICK_RS14095
uniprot id: A0A0B5BGQ2
names: Subcellular Location Annotation
messages: Mitochondrion

345632:GPICK RS11900
gene id: 345632:GPICK_RS11900
uniprot id: A0A0B5BB20
names: Similarity
messages: Belongs to the YggT family.

345632:GPICK RS10010
gene id: 345632:GPICK_RS10010
uniprot id: A0A0B5BHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

345632:GPICK RS14320
gene id: 345632:GPICK_RS14320
uniprot id: A0A0B5BJY8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS14415
gene id: 345632:GPICK_RS14415
uniprot id: A0A0B5BGW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

345632:GPICK RS11675
gene id: 345632:GPICK_RS11675
uniprot id: A0A0B5BIP6
names: Similarity
messages: Belongs to the AlaDH/PNT family.

345632:GPICK RS13340
gene id: 345632:GPICK_RS13340
uniprot id: A0A0B5BBS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

345632:GPICK RS08600
gene id: 345632:GPICK_RS08600
uniprot id: A0A0B5BFV9
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS12595
gene id: 345632:GPICK_RS12595
uniprot id: A0A0B5BHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Membrane

345632:GPICK RS15865
gene id: 345632:GPICK_RS15865
uniprot id: A0A0B5BHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS15275
gene id: 345632:GPICK_RS15275
uniprot id: A0A0B5BDJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

345632:GPICK RS15115
gene id: 345632:GPICK_RS15115
uniprot id: A0A0B5BKC5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

345632:GPICK RS04625
gene id: 345632:GPICK_RS04625
uniprot id: A0A0B5B868
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

345632:GPICK RS00900
gene id: 345632:GPICK_RS00900
uniprot id: A0A0B5B6H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

345632:GPICK RS07030
gene id: 345632:GPICK_RS07030
uniprot id: A0A0B5B8W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

345632:GPICK RS09340
gene id: 345632:GPICK_RS09340
uniprot id: A0A0B5BAB8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

345632:GPICK RS10295
gene id: 345632:GPICK_RS10295
uniprot id: A0A0B5BI14
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

345632:GPICK RS11705
gene id: 345632:GPICK_RS11705
uniprot id: A0A0B5BBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

345632:GPICK RS10490
gene id: 345632:GPICK_RS10490
uniprot id: A0A0B5BAY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

345632:GPICK RS00285
gene id: 345632:GPICK_RS00285
uniprot id: A0A0B5BD44
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS14235
gene id: 345632:GPICK_RS14235
uniprot id: A0A0B5BIR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

345632:GPICK RS09810
gene id: 345632:GPICK_RS09810
uniprot id: A0A0B5BHT1
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

345632:GPICK RS10580
gene id: 345632:GPICK_RS10580
uniprot id: A0A0B5BB00
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

345632:GPICK RS03285
gene id: 345632:GPICK_RS03285
uniprot id: A0A0B5BBW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

345632:GPICK RS03375
gene id: 345632:GPICK_RS03375
uniprot id: A0A0B5B7J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

345632:GPICK RS03455
gene id: 345632:GPICK_RS03455
uniprot id: A0A0B5B7K3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

345632:GPICK RS09955
gene id: 345632:GPICK_RS09955
uniprot id: A0A0B5BK88
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

345632:GPICK RS09240
gene id: 345632:GPICK_RS09240
uniprot id: A0A0B5B9V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

345632:GPICK RS03730
gene id: 345632:GPICK_RS03730
uniprot id: A0A0B5BJY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS12535
gene id: 345632:GPICK_RS12535
uniprot id: A0A0B5BHW8
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

345632:GPICK RS07270
gene id: 345632:GPICK_RS07270
uniprot id: A0A0B5B8Y8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

345632:GPICK RS15065
gene id: 345632:GPICK_RS15065
uniprot id: A0A0B5BJ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

345632:GPICK RS00485
gene id: 345632:GPICK_RS00485
uniprot id: A0A0B5BAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family. PetJ subfamily.
messages: Cellular thylakoid lumen

345632:GPICK RS07040
gene id: 345632:GPICK_RS07040
uniprot id: A0A0B5BDE8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

345632:GPICK RS07900
gene id: 345632:GPICK_RS07900
uniprot id: A0A0B5B974
names: Similarity
messages: Belongs to the peptidase M29 family.

345632:GPICK RS14585
gene id: 345632:GPICK_RS14585
uniprot id: A0A0B5BE09
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

345632:GPICK RS07080
gene id: 345632:GPICK_RS07080
uniprot id: A0A0B5B9B7
names: Similarity
messages: Belongs to the aspartokinase family.

345632:GPICK RS08490
gene id: 345632:GPICK_RS08490
uniprot id: A0A0B5B9Y3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

345632:GPICK RS09925
gene id: 345632:GPICK_RS09925
uniprot id: A0A0B5BA84
names: Similarity
messages: Belongs to the glutamate synthase family.

345632:GPICK RS01010
gene id: 345632:GPICK_RS01010
uniprot id: A0A0B5B6J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

345632:GPICK RS09950
gene id: 345632:GPICK_RS09950
uniprot id: A0A0B5BA92
names: Similarity
messages: Belongs to the peptidase S49 family.

345632:GPICK RS03750
gene id: 345632:GPICK_RS03750
uniprot id: A0A0B5BC42
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

345632:GPICK RS11885
gene id: 345632:GPICK_RS11885
uniprot id: A0A0B5BHK9
names: Similarity
messages: Belongs to the peptidase C40 family.

345632:GPICK RS10465
gene id: 345632:GPICK_RS10465
uniprot id: A0A0B5BAX3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS05265
gene id: 345632:GPICK_RS05265
uniprot id: A0A0B5B8I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

345632:GPICK RS15725
gene id: 345632:GPICK_RS15725
uniprot id: A0A0B5BHG8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS04990
gene id: 345632:GPICK_RS04990
uniprot id: A0A0B5BFF8
names: Similarity
messages: Belongs to the FemABX family.

345632:GPICK RS10360
gene id: 345632:GPICK_RS10360
uniprot id: A0A0B5BEX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

345632:GPICK RS06015
gene id: 345632:GPICK_RS06015
uniprot id: A0A0B5B8U4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS08880
gene id: 345632:GPICK_RS08880
uniprot id: A0A0B5BHE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

345632:GPICK RS14875
gene id: 345632:GPICK_RS14875
uniprot id: A0A0B5BK82
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

345632:GPICK RS04580
gene id: 345632:GPICK_RS04580
uniprot id: A0A0B5BDX3
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

345632:GPICK RS12885
gene id: 345632:GPICK_RS12885
uniprot id: A0A0B5BJ89
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

345632:GPICK RS13225
gene id: 345632:GPICK_RS13225
uniprot id: A0A0B5BCE6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS00005
gene id: 345632:GPICK_RS00005
uniprot id: A0A0B5BCZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

345632:GPICK RS14000
gene id: 345632:GPICK_RS14000
uniprot id: A0A0B5BGL0
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

345632:GPICK RS14395
gene id: 345632:GPICK_RS14395
uniprot id: A0A0B5BJZ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

345632:GPICK RS15605
gene id: 345632:GPICK_RS15605
uniprot id: A0A0B5BD02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

345632:GPICK RS10725
gene id: 345632:GPICK_RS10725
uniprot id: A0A0B5BAJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

345632:GPICK RS11765
gene id: 345632:GPICK_RS11765
uniprot id: A0A0B5BFM6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS13805
gene id: 345632:GPICK_RS13805
uniprot id: A0A0B5BIE5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

345632:GPICK RS06470
gene id: 345632:GPICK_RS06470
uniprot id: A0A0B5B8N0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

345632:GPICK RS08495
gene id: 345632:GPICK_RS08495
uniprot id: A0A0B5B9L1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

345632:GPICK RS05075
gene id: 345632:GPICK_RS05075
uniprot id: A0A0B5BCL0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

345632:GPICK RS07860
gene id: 345632:GPICK_RS07860
uniprot id: A0A0B5BDT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

345632:GPICK RS08635
gene id: 345632:GPICK_RS08635
uniprot id: A0A0B5BA05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

345632:GPICK RS11530
gene id: 345632:GPICK_RS11530
uniprot id: A0A0B5BBI6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

345632:GPICK RS01675
gene id: 345632:GPICK_RS01675
uniprot id: A0A0B5BBB8
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS10135
gene id: 345632:GPICK_RS10135
uniprot id: A0A0B5BES8
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

345632:GPICK RS07175
gene id: 345632:GPICK_RS07175
uniprot id: A0A0B5B9C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

345632:GPICK RS02200
gene id: 345632:GPICK_RS02200
uniprot id: A0A0B5BCT3
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

345632:GPICK RS08015
gene id: 345632:GPICK_RS08015
uniprot id: A0A0B5BK69
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

345632:GPICK RS07865
gene id: 345632:GPICK_RS07865
uniprot id: A0A0B5BGV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

345632:GPICK RS13385
gene id: 345632:GPICK_RS13385
uniprot id: A0A0B5BIF4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

345632:GPICK RS04615
gene id: 345632:GPICK_RS04615
uniprot id: A0A0B5BDX9
names: Similarity
messages: Belongs to the citrate synthase family.

345632:GPICK RS10825
gene id: 345632:GPICK_RS10825
uniprot id: A0A0B5BAL4
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00750
gene id: 345632:GPICK_RS00750
uniprot id: A0A0B5BDE1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

345632:GPICK RS11720
gene id: 345632:GPICK_RS11720
uniprot id: A0A0B5BHI1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS04125
gene id: 345632:GPICK_RS04125
uniprot id: A0A0B5B7W8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00810
gene id: 345632:GPICK_RS00810
uniprot id: A0A0B5BDF1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS15590
gene id: 345632:GPICK_RS15590
uniprot id: A0A0B5BJC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

345632:GPICK RS14850
gene id: 345632:GPICK_RS14850
uniprot id: A0A0B5BDC2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

345632:GPICK RS06080
gene id: 345632:GPICK_RS06080
uniprot id: A0A0B5BEN2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

345632:GPICK RS06225
gene id: 345632:GPICK_RS06225
uniprot id: A0A0B5B8Y5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

345632:GPICK RS03350
gene id: 345632:GPICK_RS03350
uniprot id: A0A0B5B7J0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

345632:GPICK RS03870
gene id: 345632:GPICK_RS03870
uniprot id: A0A0B5BDL0
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS14385
gene id: 345632:GPICK_RS14385
uniprot id: A0A0B5BGW5
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

345632:GPICK RS09120
gene id: 345632:GPICK_RS09120
uniprot id: A0A0B5BA75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

345632:GPICK RS10210
gene id: 345632:GPICK_RS10210
uniprot id: A0A0B5BHZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

345632:GPICK RS07960
gene id: 345632:GPICK_RS07960
uniprot id: A0A0B5BFI8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

345632:GPICK RS03270
gene id: 345632:GPICK_RS03270
uniprot id: A0A0B5BEN3
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

345632:GPICK RS01395
gene id: 345632:GPICK_RS01395
uniprot id: A0A0B5BDQ3
names: Similarity
messages: Belongs to the LarC family.

345632:GPICK RS13075
gene id: 345632:GPICK_RS13075
uniprot id: A0A0B5BBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS14325
gene id: 345632:GPICK_RS14325
uniprot id: A0A0B5BD27
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

345632:GPICK RS08035
gene id: 345632:GPICK_RS08035
uniprot id: A0A0B5B9A8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

345632:GPICK RS06795
gene id: 345632:GPICK_RS06795
uniprot id: A0A0B5B6H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

345632:GPICK RS15325
gene id: 345632:GPICK_RS15325
uniprot id: A0A0B5BJ85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

345632:GPICK RS13285
gene id: 345632:GPICK_RS13285
uniprot id: A0A0B5BBR1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS14780
gene id: 345632:GPICK_RS14780
uniprot id: A0A0B5BCM1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS13825
gene id: 345632:GPICK_RS13825
uniprot id: A0A0B5BGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

345632:GPICK RS16325
gene id: 345632:GPICK_RS16325
uniprot id: A0A0B5BHS6
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

345632:GPICK RS14715
gene id: 345632:GPICK_RS14715
uniprot id: A0A0B5BIZ5
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

345632:GPICK RS10245
gene id: 345632:GPICK_RS10245
uniprot id: A0A0B5BAS0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

345632:GPICK RS07850
gene id: 345632:GPICK_RS07850
uniprot id: A0A0B5BDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

345632:GPICK RS05060
gene id: 345632:GPICK_RS05060
uniprot id: A0A0B5BFH0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

345632:GPICK RS02435
gene id: 345632:GPICK_RS02435
uniprot id: A0A0B5B797
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

345632:GPICK RS07410
gene id: 345632:GPICK_RS07410
uniprot id: A0A0B5B9G8
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

345632:GPICK RS06055
gene id: 345632:GPICK_RS06055
uniprot id: A0A0B5BEM6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

345632:GPICK RS13175
gene id: 345632:GPICK_RS13175
uniprot id: A0A0B5BLK0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

345632:GPICK RS14045
gene id: 345632:GPICK_RS14045
uniprot id: A0A0B5BJR9
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS06335
gene id: 345632:GPICK_RS06335
uniprot id: A0A0B5BES9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

345632:GPICK RS06845
gene id: 345632:GPICK_RS06845
uniprot id: A0A0B5B979
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

345632:GPICK RS16465
gene id: 345632:GPICK_RS16465
uniprot id: A0A0B5BDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

345632:GPICK RS04520
gene id: 345632:GPICK_RS04520
uniprot id: A0A0B5B807
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

345632:GPICK RS09815
gene id: 345632:GPICK_RS09815
uniprot id: A0A0B5BAK4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

345632:GPICK RS05685
gene id: 345632:GPICK_RS05685
uniprot id: A0A0B5BEG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

345632:GPICK RS09495
gene id: 345632:GPICK_RS09495
uniprot id: A0A0B5BGB3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS14655
gene id: 345632:GPICK_RS14655
uniprot id: A0A0B5BH00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS12130
gene id: 345632:GPICK_RS12130
uniprot id: A0A0B5BB54
names: Similarity
messages: Belongs to the P(II) protein family.

345632:GPICK RS10450
gene id: 345632:GPICK_RS10450
uniprot id: A0A0B5BEZ1
names: Similarity
messages: Belongs to the UPF0434 family.

345632:GPICK RS06560
gene id: 345632:GPICK_RS06560
uniprot id: A0A0B5B945
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

345632:GPICK RS16460
gene id: 345632:GPICK_RS16460
uniprot id: A0A0B5BE47
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

345632:GPICK RS06065
gene id: 345632:GPICK_RS06065
uniprot id: A0A0B5B8V2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS10585
gene id: 345632:GPICK_RS10585
uniprot id: A0A0B5BAH9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

345632:GPICK RS09305
gene id: 345632:GPICK_RS09305
uniprot id: A0A0B5BG75
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

345632:GPICK RS09175
gene id: 345632:GPICK_RS09175
uniprot id: A0A0B5BA82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

345632:GPICK RS16195
gene id: 345632:GPICK_RS16195
uniprot id: A0A0B5BDZ4
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

345632:GPICK RS14005
gene id: 345632:GPICK_RS14005
uniprot id: A0A0B5BII6
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS14035
gene id: 345632:GPICK_RS14035
uniprot id: A0A0B5BGL5
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

345632:GPICK RS03195
gene id: 345632:GPICK_RS03195
uniprot id: A0A0B5B7H5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS04345
gene id: 345632:GPICK_RS04345
uniprot id: A0A0B5BDT9
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Heterodimer of a large and a small subunit.

345632:GPICK RS12110
gene id: 345632:GPICK_RS12110
uniprot id: A0A0B5BHP5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

345632:GPICK RS00010
gene id: 345632:GPICK_RS00010
uniprot id: A0A0B5B5Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

345632:GPICK RS16150
gene id: 345632:GPICK_RS16150
uniprot id: A0A0B5BHP4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

345632:GPICK RS11800
gene id: 345632:GPICK_RS11800
uniprot id: A0A0B5BHJ4
names: Similarity
messages: Belongs to the TrpC family.

345632:GPICK RS05305
gene id: 345632:GPICK_RS05305
uniprot id: A0A0B5BEC2
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

345632:GPICK RS11815
gene id: 345632:GPICK_RS11815
uniprot id: A0A0B5BB07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

345632:GPICK RS08745
gene id: 345632:GPICK_RS08745
uniprot id: A0A0B5BHC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS15595
gene id: 345632:GPICK_RS15595
uniprot id: A0A0B5BKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

345632:GPICK RS01165
gene id: 345632:GPICK_RS01165
uniprot id: A0A0B5BB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS11200
gene id: 345632:GPICK_RS11200
uniprot id: A0A0B5BAS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

345632:GPICK RS18050
gene id: 345632:GPICK_RS18050
uniprot id: A0A0B5BDW2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS16350
gene id: 345632:GPICK_RS16350
uniprot id: A0A0B5BDE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

345632:GPICK RS11045
gene id: 345632:GPICK_RS11045
uniprot id: A0A0B5BF92
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

345632:GPICK RS12410
gene id: 345632:GPICK_RS12410
uniprot id: A0A0B5BB96
names: Subcellular Location Annotation
messages: Periplasm

345632:GPICK RS14345
gene id: 345632:GPICK_RS14345
uniprot id: A0A0B5BJZ1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

345632:GPICK RS09550
gene id: 345632:GPICK_RS09550
uniprot id: A0A0B5BGC5
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS07130
gene id: 345632:GPICK_RS07130
uniprot id: A0A0B5B8X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

345632:GPICK RS16210
gene id: 345632:GPICK_RS16210
uniprot id: A0A0B5BJM5
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

345632:GPICK RS01650
gene id: 345632:GPICK_RS01650
uniprot id: A0A0B5BDV0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS00295
gene id: 345632:GPICK_RS00295
uniprot id: A0A0B5B677
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

345632:GPICK RS14280
gene id: 345632:GPICK_RS14280
uniprot id: A0A0B5BGU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

345632:GPICK RS06130
gene id: 345632:GPICK_RS06130
uniprot id: A0A0B5BD35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

345632:GPICK RS02385
gene id: 345632:GPICK_RS02385
uniprot id: A0A0B5B788
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

345632:GPICK RS09235
gene id: 345632:GPICK_RS09235
uniprot id: A0A0B5BA91
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS10470
gene id: 345632:GPICK_RS10470
uniprot id: A0A0B5BAG6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

345632:GPICK RS09540
gene id: 345632:GPICK_RS09540
uniprot id: A0A0B5BA16
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15670
gene id: 345632:GPICK_RS15670
uniprot id: A0A0B5BJE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

345632:GPICK RS10340
gene id: 345632:GPICK_RS10340
uniprot id: A0A0B5BGQ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

345632:GPICK RS05160
gene id: 345632:GPICK_RS05160
uniprot id: A0A0B5B869
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

345632:GPICK RS00985
gene id: 345632:GPICK_RS00985
uniprot id: A0A0B5B6I7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

345632:GPICK RS06085
gene id: 345632:GPICK_RS06085
uniprot id: A0A0B5BG05
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS06780
gene id: 345632:GPICK_RS06780
uniprot id: A0A0B5BDS3
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

345632:GPICK RS08375
gene id: 345632:GPICK_RS08375
uniprot id: A0A0B5B9W4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS08240
gene id: 345632:GPICK_RS08240
uniprot id: A0A0B5BDZ8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

345632:GPICK RS10190
gene id: 345632:GPICK_RS10190
uniprot id: A0A0B5BAD3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS07060
gene id: 345632:GPICK_RS07060
uniprot id: A0A0B5B8W7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

345632:GPICK RS06650
gene id: 345632:GPICK_RS06650
uniprot id: A0A0B5BAW2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

345632:GPICK RS02600
gene id: 345632:GPICK_RS02600
uniprot id: A0A0B5B791
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

345632:GPICK RS08505
gene id: 345632:GPICK_RS08505
uniprot id: A0A0B5BFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

345632:GPICK RS12705
gene id: 345632:GPICK_RS12705
uniprot id: A0A0B5BJ65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

345632:GPICK RS11880
gene id: 345632:GPICK_RS11880
uniprot id: A0A0B5BFN9
names: Similarity
messages: Belongs to the Nudix hydrolase family.

345632:GPICK RS01335
gene id: 345632:GPICK_RS01335
uniprot id: A0A0B5BDP5
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03210
gene id: 345632:GPICK_RS03210
uniprot id: A0A0B5BD94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

345632:GPICK RS02455
gene id: 345632:GPICK_RS02455
uniprot id: A0A0B5BEB2
names: Similarity
messages: Belongs to the FlgM family.

345632:GPICK RS10155
gene id: 345632:GPICK_RS10155
uniprot id: A0A0B5BHY9
names: Similarity
messages: Belongs to the AOR/FOR family.

345632:GPICK RS06070
gene id: 345632:GPICK_RS06070
uniprot id: A0A0B5B8I0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

345632:GPICK RS07820
gene id: 345632:GPICK_RS07820
uniprot id: A0A0B5BDP4
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

345632:GPICK RS04180
gene id: 345632:GPICK_RS04180
uniprot id: A0A0B5BF22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

345632:GPICK RS04695
gene id: 345632:GPICK_RS04695
uniprot id: A0A0B5BDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

345632:GPICK RS16040
gene id: 345632:GPICK_RS16040
uniprot id: A0A0B5BD75
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

345632:GPICK RS03265
gene id: 345632:GPICK_RS03265
uniprot id: A0A0B5BD99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

345632:GPICK RS04335
gene id: 345632:GPICK_RS04335
uniprot id: A0A0B5B7Z1
names: Similarity
messages: Belongs to the peptidase C1 family.

345632:GPICK RS01670
gene id: 345632:GPICK_RS01670
uniprot id: A0A0B5B6U0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

345632:GPICK RS03385
gene id: 345632:GPICK_RS03385
uniprot id: A0A0B5BBY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

345632:GPICK RS08165
gene id: 345632:GPICK_RS08165
uniprot id: A0A0B5BH40
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS15415
gene id: 345632:GPICK_RS15415
uniprot id: A0A0B5BCW2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

345632:GPICK RS13345
gene id: 345632:GPICK_RS13345
uniprot id: A0A0B5BGC6
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS14430
gene id: 345632:GPICK_RS14430
uniprot id: A0A0B5BD47
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS13140
gene id: 345632:GPICK_RS13140
uniprot id: A0A0B5BGA3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

345632:GPICK RS13010
gene id: 345632:GPICK_RS13010
uniprot id: A0A0B5BI28
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

345632:GPICK RS14680
gene id: 345632:GPICK_RS14680
uniprot id: A0A0B5BH02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

345632:GPICK RS12115
gene id: 345632:GPICK_RS12115
uniprot id: A0A0B5BLI6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

345632:GPICK RS03895
gene id: 345632:GPICK_RS03895
uniprot id: A0A0B5BDL4
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS11460
gene id: 345632:GPICK_RS11460
uniprot id: A0A0B5BIM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family. PetJ subfamily.
messages: Cellular thylakoid lumen

345632:GPICK RS04090
gene id: 345632:GPICK_RS04090
uniprot id: A0A0B5B7W4
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00470
gene id: 345632:GPICK_RS00470
uniprot id: A0A0B5BD87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS06020
gene id: 345632:GPICK_RS06020
uniprot id: A0A0B5B8H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

345632:GPICK RS11775
gene id: 345632:GPICK_RS11775
uniprot id: A0A0B5BIR6
names: Similarity
messages: Belongs to the LEA type 2 family.

345632:GPICK RS01490
gene id: 345632:GPICK_RS01490
uniprot id: A0A0B5BB90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

345632:GPICK RS00095
gene id: 345632:GPICK_RS00095
uniprot id: A0A0B5B659
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

345632:GPICK RS14335
gene id: 345632:GPICK_RS14335
uniprot id: A0A0B5BGV6
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03875
gene id: 345632:GPICK_RS03875
uniprot id: A0A0B5BEX5
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03445
gene id: 345632:GPICK_RS03445
uniprot id: A0A0B5BDD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

345632:GPICK RS16365
gene id: 345632:GPICK_RS16365
uniprot id: A0A0B5BKY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TolB family.
messages: Periplasm

345632:GPICK RS12960
gene id: 345632:GPICK_RS12960
uniprot id: A0A0B5BI19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

345632:GPICK RS03335
gene id: 345632:GPICK_RS03335
uniprot id: A0A0B5BBX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

345632:GPICK RS00600
gene id: 345632:GPICK_RS00600
uniprot id: A0A0B5BAT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS13610
gene id: 345632:GPICK_RS13610
uniprot id: A0A0B5BGF1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

345632:GPICK RS08480
gene id: 345632:GPICK_RS08480
uniprot id: A0A0B5BFU3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

345632:GPICK RS01300
gene id: 345632:GPICK_RS01300
uniprot id: A0A0B5BB66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

345632:GPICK RS00290
gene id: 345632:GPICK_RS00290
uniprot id: A0A0B5B644
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS13045
gene id: 345632:GPICK_RS13045
uniprot id: A0A0B5BCB6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

345632:GPICK RS03670
gene id: 345632:GPICK_RS03670
uniprot id: A0A0B5B7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

345632:GPICK RS07145
gene id: 345632:GPICK_RS07145
uniprot id: A0A0B5BGI9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

345632:GPICK RS14660
gene id: 345632:GPICK_RS14660
uniprot id: A0A0B5BIY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

345632:GPICK RS11305
gene id: 345632:GPICK_RS11305
uniprot id: A0A0B5BAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

345632:GPICK RS04020
gene id: 345632:GPICK_RS04020
uniprot id: A0A0B5BDN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

345632:GPICK RS05005
gene id: 345632:GPICK_RS05005
uniprot id: A0A0B5BCK1
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01640
gene id: 345632:GPICK_RS01640
uniprot id: A0A0B5BBB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

345632:GPICK RS10175
gene id: 345632:GPICK_RS10175
uniprot id: A0A0B5BGM3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

345632:GPICK RS08455
gene id: 345632:GPICK_RS08455
uniprot id: A0A0B5BH78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS04785
gene id: 345632:GPICK_RS04785
uniprot id: A0A0B5BCH1
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

345632:GPICK RS16095
gene id: 345632:GPICK_RS16095
uniprot id: A0A0B5BD86
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS01765
gene id: 345632:GPICK_RS01765
uniprot id: A0A0B5BBD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

345632:GPICK RS01405
gene id: 345632:GPICK_RS01405
uniprot id: A0A0B5B6P0
names: Similarity
messages: Belongs to the CinA family.

345632:GPICK RS14960
gene id: 345632:GPICK_RS14960
uniprot id: A0A0B5BCN6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

345632:GPICK RS05545
gene id: 345632:GPICK_RS05545
uniprot id: A0A0B5BCU3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

345632:GPICK RS11930
gene id: 345632:GPICK_RS11930
uniprot id: A0A0B5BFP8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

345632:GPICK RS10070
gene id: 345632:GPICK_RS10070
uniprot id: A0A0B5BGK8
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

345632:GPICK RS03680
gene id: 345632:GPICK_RS03680
uniprot id: A0A0B5BDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

345632:GPICK RS05210
gene id: 345632:GPICK_RS05210
uniprot id: A0A0B5B875
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS05760
gene id: 345632:GPICK_RS05760
uniprot id: A0A0B5BEH6
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS02075
gene id: 345632:GPICK_RS02075
uniprot id: A0A0B5B725
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

345632:GPICK RS02360
gene id: 345632:GPICK_RS02360
uniprot id: A0A0B5B782
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS02700
gene id: 345632:GPICK_RS02700
uniprot id: A0A0B5BEE5
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

345632:GPICK RS09845
gene id: 345632:GPICK_RS09845
uniprot id: A0A0B5BA72
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS02250
gene id: 345632:GPICK_RS02250
uniprot id: A0A0B5BCU5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

345632:GPICK RS13350
gene id: 345632:GPICK_RS13350
uniprot id: A0A0B5BI73
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

345632:GPICK RS15665
gene id: 345632:GPICK_RS15665
uniprot id: A0A0B5BHF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

345632:GPICK RS02410
gene id: 345632:GPICK_RS02410
uniprot id: A0A0B5B792
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

345632:GPICK RS10595
gene id: 345632:GPICK_RS10595
uniprot id: A0A0B5BGU9
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

345632:GPICK RS10750
gene id: 345632:GPICK_RS10750
uniprot id: A0A0B5BB37
names: Similarity
messages: Belongs to the TlyA family.

345632:GPICK RS15185
gene id: 345632:GPICK_RS15185
uniprot id: A0A0B5BH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

345632:GPICK RS10605
gene id: 345632:GPICK_RS10605
uniprot id: A0A0B5BB06
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

345632:GPICK RS05595
gene id: 345632:GPICK_RS05595
uniprot id: A0A0B5B8D1
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

345632:GPICK RS02540
gene id: 345632:GPICK_RS02540
uniprot id: A0A0B5BCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

345632:GPICK RS05065
gene id: 345632:GPICK_RS05065
uniprot id: A0A0B5B8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

345632:GPICK RS03915
gene id: 345632:GPICK_RS03915
uniprot id: A0A0B5BC61
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

345632:GPICK RS07990
gene id: 345632:GPICK_RS07990
uniprot id: A0A0B5BGY3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

345632:GPICK RS12475
gene id: 345632:GPICK_RS12475
uniprot id: A0A0B5BBA2
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03200
gene id: 345632:GPICK_RS03200
uniprot id: A0A0B5B7L0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS15555
gene id: 345632:GPICK_RS15555
uniprot id: A0A0B5BHD4
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS03465
gene id: 345632:GPICK_RS03465
uniprot id: A0A0B5BC03
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08105
gene id: 345632:GPICK_RS08105
uniprot id: A0A0B5BH11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

345632:GPICK RS15190
gene id: 345632:GPICK_RS15190
uniprot id: A0A0B5BJ70
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

345632:GPICK RS06805
gene id: 345632:GPICK_RS06805
uniprot id: A0A0B5BGE6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

345632:GPICK RS15255
gene id: 345632:GPICK_RS15255
uniprot id: A0A0B5BCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

345632:GPICK RS08115
gene id: 345632:GPICK_RS08115
uniprot id: A0A0B5B9C6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

345632:GPICK RS16270
gene id: 345632:GPICK_RS16270
uniprot id: A0A0B5BKX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

345632:GPICK RS15500
gene id: 345632:GPICK_RS15500
uniprot id: A0A0B5BHC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

345632:GPICK RS06600
gene id: 345632:GPICK_RS06600
uniprot id: A0A0B5B8P9
names: Similarity
messages: Belongs to the AOR/FOR family.

345632:GPICK RS15485
gene id: 345632:GPICK_RS15485
uniprot id: A0A0B5BKJ2
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

345632:GPICK RS02210
gene id: 345632:GPICK_RS02210
uniprot id: A0A0B5B743
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

345632:GPICK RS01990
gene id: 345632:GPICK_RS01990
uniprot id: A0A0B5B6Z4
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

345632:GPICK RS01455
gene id: 345632:GPICK_RS01455
uniprot id: A0A0B5B6P5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

345632:GPICK RS06145
gene id: 345632:GPICK_RS06145
uniprot id: A0A0B5BG14
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

345632:GPICK RS03355
gene id: 345632:GPICK_RS03355
uniprot id: A0A0B5B7M9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

345632:GPICK RS01485
gene id: 345632:GPICK_RS01485
uniprot id: A0A0B5B6Q5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

345632:GPICK RS03365
gene id: 345632:GPICK_RS03365
uniprot id: A0A0B5BDC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

345632:GPICK RS08625
gene id: 345632:GPICK_RS08625
uniprot id: A0A0B5BFW3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS04960
gene id: 345632:GPICK_RS04960
uniprot id: A0A0B5BE32
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03865
gene id: 345632:GPICK_RS03865
uniprot id: A0A0B5BC53
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS02730
gene id: 345632:GPICK_RS02730
uniprot id: A0A0B5BEE8
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

345632:GPICK RS08730
gene id: 345632:GPICK_RS08730
uniprot id: A0A0B5B9N8
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

345632:GPICK RS12540
gene id: 345632:GPICK_RS12540
uniprot id: A0A0B5BJ38
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

345632:GPICK RS02275
gene id: 345632:GPICK_RS02275
uniprot id: A0A0B5BBM1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

345632:GPICK RS13165
gene id: 345632:GPICK_RS13165
uniprot id: A0A0B5BBN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

345632:GPICK RS14790
gene id: 345632:GPICK_RS14790
uniprot id: A0A0B5BJ10
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

345632:GPICK RS16145
gene id: 345632:GPICK_RS16145
uniprot id: A0A0B5BD96
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

345632:GPICK RS03205
gene id: 345632:GPICK_RS03205
uniprot id: A0A0B5BBW5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS07050
gene id: 345632:GPICK_RS07050
uniprot id: A0A0B5BGH9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

345632:GPICK RS03370
gene id: 345632:GPICK_RS03370
uniprot id: A0A0B5BEQ4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

345632:GPICK RS04860
gene id: 345632:GPICK_RS04860
uniprot id: A0A0B5B835
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

345632:GPICK RS02430
gene id: 345632:GPICK_RS02430
uniprot id: A0A0B5B770
names: Similarity
names: Subunit
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

345632:GPICK RS10715
gene id: 345632:GPICK_RS10715
uniprot id: A0A0B5BI91
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

345632:GPICK RS08420
gene id: 345632:GPICK_RS08420
uniprot id: A0A0B5BH72
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

345632:GPICK RS02885
gene id: 345632:GPICK_RS02885
uniprot id: A0A0B5B7D4
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

345632:GPICK RS04075
gene id: 345632:GPICK_RS04075
uniprot id: A0A0B5BDP6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

345632:GPICK RS07975
gene id: 345632:GPICK_RS07975
uniprot id: A0A0B5B992
names: Similarity
messages: Belongs to the archease family.

345632:GPICK RS16330
gene id: 345632:GPICK_RS16330
uniprot id: A0A0B5BKG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

345632:GPICK RS02470
gene id: 345632:GPICK_RS02470
uniprot id: A0A0B5BBN7
names: Similarity
messages: Belongs to the bacterial flagellin family.

345632:GPICK RS04260
gene id: 345632:GPICK_RS04260
uniprot id: A0A0B5B800
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

345632:GPICK RS11465
gene id: 345632:GPICK_RS11465
uniprot id: A0A0B5BBH7
names: Similarity
messages: Belongs to the peptidase S16 family.

345632:GPICK RS15320
gene id: 345632:GPICK_RS15320
uniprot id: A0A0B5BH87
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS01380
gene id: 345632:GPICK_RS01380
uniprot id: A0A0B5BB73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

345632:GPICK RS11175
gene id: 345632:GPICK_RS11175
uniprot id: A0A0B5BFE5
names: Similarity
messages: Belongs to the PstS family.

345632:GPICK RS11195
gene id: 345632:GPICK_RS11195
uniprot id: A0A0B5BBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

345632:GPICK RS15300
gene id: 345632:GPICK_RS15300
uniprot id: A0A0B5BKF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS03100
gene id: 345632:GPICK_RS03100
uniprot id: A0A0B5BBV8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS15695
gene id: 345632:GPICK_RS15695
uniprot id: A0A0B5B966
names: Similarity
messages: Belongs to the HdrA family.

345632:GPICK RS05680
gene id: 345632:GPICK_RS05680
uniprot id: A0A0B5BCW1
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

345632:GPICK RS02665
gene id: 345632:GPICK_RS02665
uniprot id: A0A0B5BBQ2
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

345632:GPICK RS01615
gene id: 345632:GPICK_RS01615
uniprot id: A0A0B5BBA8
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS09840
gene id: 345632:GPICK_RS09840
uniprot id: A0A0B5BAK9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

345632:GPICK RS12695
gene id: 345632:GPICK_RS12695
uniprot id: A0A0B5BG43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

345632:GPICK RS04865
gene id: 345632:GPICK_RS04865
uniprot id: A0A0B5BCI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

345632:GPICK RS07810
gene id: 345632:GPICK_RS07810
uniprot id: A0A0B5B9K8
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

345632:GPICK RS02235
gene id: 345632:GPICK_RS02235
uniprot id: A0A0B5B746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

345632:GPICK RS15655
gene id: 345632:GPICK_RS15655
uniprot id: A0A0B5BDR3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

345632:GPICK RS11910
gene id: 345632:GPICK_RS11910
uniprot id: A0A0B5BHL3
names: Similarity
messages: Belongs to the UPF0235 family.

345632:GPICK RS05645
gene id: 345632:GPICK_RS05645
uniprot id: A0A0B5BCV7
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

345632:GPICK RS05080
gene id: 345632:GPICK_RS05080
uniprot id: A0A0B5BE48
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

345632:GPICK RS16130
gene id: 345632:GPICK_RS16130
uniprot id: A0A0B5BJL1
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

345632:GPICK RS09070
gene id: 345632:GPICK_RS09070
uniprot id: A0A0B5BG36
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

345632:GPICK RS03740
gene id: 345632:GPICK_RS03740
uniprot id: A0A0B5B7P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

345632:GPICK RS12125
gene id: 345632:GPICK_RS12125
uniprot id: A0A0B5BBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS06140
gene id: 345632:GPICK_RS06140
uniprot id: A0A0B5BDR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

345632:GPICK RS11955
gene id: 345632:GPICK_RS11955
uniprot id: A0A0B5BB29
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS14600
gene id: 345632:GPICK_RS14600
uniprot id: A0A0B5BGZ2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

345632:GPICK RS16310
gene id: 345632:GPICK_RS16310
uniprot id: A0A0B5BKX5
names: Similarity
messages: Belongs to the CapA family.

345632:GPICK RS02765
gene id: 345632:GPICK_RS02765
uniprot id: A0A0B5B7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

345632:GPICK RS12490
gene id: 345632:GPICK_RS12490
uniprot id: A0A0B5BJ30
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

345632:GPICK RS02475
gene id: 345632:GPICK_RS02475
uniprot id: A0A0B5BCX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

345632:GPICK RS09205
gene id: 345632:GPICK_RS09205
uniprot id: A0A0B5BA86
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

345632:GPICK RS05915
gene id: 345632:GPICK_RS05915
uniprot id: A0A0B5BEK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

345632:GPICK RS14050
gene id: 345632:GPICK_RS14050
uniprot id: A0A0B5BCV5
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

345632:GPICK RS01240
gene id: 345632:GPICK_RS01240
uniprot id: A0A0B5BDM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

345632:GPICK RS02440
gene id: 345632:GPICK_RS02440
uniprot id: A0A0B5BBN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

345632:GPICK RS14240
gene id: 345632:GPICK_RS14240
uniprot id: A0A0B5BJY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

345632:GPICK RS06625
gene id: 345632:GPICK_RS06625
uniprot id: A0A0B5B8Q2
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

345632:GPICK RS15450
gene id: 345632:GPICK_RS15450
uniprot id: A0A0B5BHB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Membrane
messages: Monomer.

345632:GPICK RS00375
gene id: 345632:GPICK_RS00375
uniprot id: A0A0B5BAP9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

345632:GPICK RS04870
gene id: 345632:GPICK_RS04870
uniprot id: A0A0B5BE26
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

345632:GPICK RS13865
gene id: 345632:GPICK_RS13865
uniprot id: A0A0B5BJN0
names: Similarity
messages: Belongs to the universal stress protein A family.

345632:GPICK RS02820
gene id: 345632:GPICK_RS02820
uniprot id: A0A0B5BBR9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

345632:GPICK RS01070
gene id: 345632:GPICK_RS01070
uniprot id: A0A0B5BDJ9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-101 inactivates the nitrogenase reductase and regulates nitrogenase activity.

345632:GPICK RS10140
gene id: 345632:GPICK_RS10140
uniprot id: A0A0B5BLG6
names: Similarity
messages: Belongs to the FlgM family.

345632:GPICK RS12005
gene id: 345632:GPICK_RS12005
uniprot id: A0A0B5BIV1
names: Similarity
messages: Belongs to the peptidase S49 family.

345632:GPICK RS12140
gene id: 345632:GPICK_RS12140
uniprot id: A0A0B5BHQ1
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

345632:GPICK RS07830
gene id: 345632:GPICK_RS07830
uniprot id: A0A0B5BFG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS08175
gene id: 345632:GPICK_RS08175
uniprot id: A0A0B5B9G2
names: Similarity
messages: Belongs to the creatininase superfamily.

345632:GPICK RS03175
gene id: 345632:GPICK_RS03175
uniprot id: A0A0B5BD88
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08335
gene id: 345632:GPICK_RS08335
uniprot id: A0A0B5BFS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

345632:GPICK RS14175
gene id: 345632:GPICK_RS14175
uniprot id: A0A0B5BGT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

345632:GPICK RS00460
gene id: 345632:GPICK_RS00460
uniprot id: A0A0B5BBW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

345632:GPICK RS04250
gene id: 345632:GPICK_RS04250
uniprot id: A0A0B5BDS5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS00955
gene id: 345632:GPICK_RS00955
uniprot id: A0A0B5BAW2
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

345632:GPICK RS15105
gene id: 345632:GPICK_RS15105
uniprot id: A0A0B5BJ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

345632:GPICK RS11140
gene id: 345632:GPICK_RS11140
uniprot id: A0A0B5BBC9
names: Similarity
messages: Belongs to the citrate synthase family.

345632:GPICK RS07935
gene id: 345632:GPICK_RS07935
uniprot id: A0A0B5BFI4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

345632:GPICK RS08110
gene id: 345632:GPICK_RS08110
uniprot id: A0A0B5B9S3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

345632:GPICK RS07180
gene id: 345632:GPICK_RS07180
uniprot id: A0A0B5B8X8
names: Similarity
messages: Belongs to the GSP E family.

345632:GPICK RS02750
gene id: 345632:GPICK_RS02750
uniprot id: A0A0B5BD08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

345632:GPICK RS16305
gene id: 345632:GPICK_RS16305
uniprot id: A0A0B5BJP6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS13765
gene id: 345632:GPICK_RS13765
uniprot id: A0A0B5BCP8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS15580
gene id: 345632:GPICK_RS15580
uniprot id: A0A0B5BCZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

345632:GPICK RS18060
gene id: 345632:GPICK_RS18060
uniprot id: A0A0B5BHT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

345632:GPICK RS03190
gene id: 345632:GPICK_RS03190
uniprot id: A0A0B5BEM3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS10820
gene id: 345632:GPICK_RS10820
uniprot id: A0A0B5BB48
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00480
gene id: 345632:GPICK_RS00480
uniprot id: A0A0B5B6A0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

345632:GPICK RS15825
gene id: 345632:GPICK_RS15825
uniprot id: A0A0B5BDU3
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS05420
gene id: 345632:GPICK_RS05420
uniprot id: A0A0B5BFR0
names: Similarity
messages: Belongs to the peptidase U62 family.

345632:GPICK RS01685
gene id: 345632:GPICK_RS01685
uniprot id: A0A0B5BDV6
names: Similarity
messages: Belongs to the UPF0502 family.

345632:GPICK RS16190
gene id: 345632:GPICK_RS16190
uniprot id: A0A0B5BKV6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

345632:GPICK RS15315
gene id: 345632:GPICK_RS15315
uniprot id: A0A0B5BCU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS14665
gene id: 345632:GPICK_RS14665
uniprot id: A0A0B5BK37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

345632:GPICK RS03510
gene id: 345632:GPICK_RS03510
uniprot id: A0A0B5BES5
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

345632:GPICK RS05470
gene id: 345632:GPICK_RS05470
uniprot id: A0A0B5BED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

345632:GPICK RS15715
gene id: 345632:GPICK_RS15715
uniprot id: A0A0B5BDS3
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 [2Fe-2S] cluster per subunit.

345632:GPICK RS02490
gene id: 345632:GPICK_RS02490
uniprot id: A0A0B5B779
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

345632:GPICK RS02370
gene id: 345632:GPICK_RS02370
uniprot id: A0A0B5BCW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

345632:GPICK RS11575
gene id: 345632:GPICK_RS11575
uniprot id: A0A0B5BHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

345632:GPICK RS04660
gene id: 345632:GPICK_RS04660
uniprot id: A0A0B5B819
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS07505
gene id: 345632:GPICK_RS07505
uniprot id: A0A0B5B916
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

345632:GPICK RS14135
gene id: 345632:GPICK_RS14135
uniprot id: A0A0B5BJW5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

345632:GPICK RS05460
gene id: 345632:GPICK_RS05460
uniprot id: A0A0B5B8A8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

345632:GPICK RS00475
gene id: 345632:GPICK_RS00475
uniprot id: A0A0B5B686
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Belongs to the complex I 30 kDa subunit family.
messages: Belongs to the complex I 49 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: Cell membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 20 kDa subunit family.
messages: In the central section; belongs to the complex I 30 kDa subunit family.
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

345632:GPICK RS14420
gene id: 345632:GPICK_RS14420
uniprot id: A0A0B5BIU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

345632:GPICK RS08310
gene id: 345632:GPICK_RS08310
uniprot id: A0A0B5BFR8
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

345632:GPICK RS06040
gene id: 345632:GPICK_RS06040
uniprot id: A0A0B5B8U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

345632:GPICK RS14745
gene id: 345632:GPICK_RS14745
uniprot id: A0A0B5BK56
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

345632:GPICK RS05950
gene id: 345632:GPICK_RS05950
uniprot id: A0A0B5BEK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

345632:GPICK RS13820
gene id: 345632:GPICK_RS13820
uniprot id: A0A0B5BC26
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

345632:GPICK RS06170
gene id: 345632:GPICK_RS06170
uniprot id: A0A0B5BG20
names: Similarity
messages: Belongs to the sigma-54 factor family.

345632:GPICK RS05505
gene id: 345632:GPICK_RS05505
uniprot id: A0A0B5BFS3
names: Similarity
messages: Belongs to the PilY1 family.

345632:GPICK RS15610
gene id: 345632:GPICK_RS15610
uniprot id: A0A0B5BHE6
names: Similarity
messages: Belongs to the ParB family.

345632:GPICK RS03850
gene id: 345632:GPICK_RS03850
uniprot id: A0A0B5BEX0
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS08250
gene id: 345632:GPICK_RS08250
uniprot id: A0A0B5BH50
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

345632:GPICK RS01820
gene id: 345632:GPICK_RS01820
uniprot id: A0A0B5BBE4
names: Subcellular Location Annotation
messages: Cytoplasm

345632:GPICK RS14180
gene id: 345632:GPICK_RS14180
uniprot id: A0A0B5BIQ7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

345632:GPICK RS00185
gene id: 345632:GPICK_RS00185
uniprot id: A0A0B5BAL6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

345632:GPICK RS12880
gene id: 345632:GPICK_RS12880
uniprot id: A0A0B5BI05
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

345632:GPICK RS14165
gene id: 345632:GPICK_RS14165
uniprot id: A0A0B5BD00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

345632:GPICK RS04060
gene id: 345632:GPICK_RS04060
uniprot id: A0A0B5B7W1
names: Subunit
messages: Heterodimer of a large and a small subunit.

345632:GPICK RS06630
gene id: 345632:GPICK_RS06630
uniprot id: A0A0B5BD97
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

345632:GPICK RS13135
gene id: 345632:GPICK_RS13135
uniprot id: A0A0B5BIF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

345632:GPICK RS07945
gene id: 345632:GPICK_RS07945
uniprot id: A0A0B5B9N3
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

345632:GPICK RS00410
gene id: 345632:GPICK_RS00410
uniprot id: A0A0B5BBU9
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS00675
gene id: 345632:GPICK_RS00675
uniprot id: A0A0B5B6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

345632:GPICK RS11035
gene id: 345632:GPICK_RS11035
uniprot id: A0A0B5BB89
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

345632:GPICK RS06175
gene id: 345632:GPICK_RS06175
uniprot id: A0A0B5B8X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

345632:GPICK RS01815
gene id: 345632:GPICK_RS01815
uniprot id: A0A0B5B6Y3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

345632:GPICK RS00070
gene id: 345632:GPICK_RS00070
uniprot id: A0A0B5BBP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

345632:GPICK RS10775
gene id: 345632:GPICK_RS10775
uniprot id: A0A0B5BGY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

345632:GPICK RS06645
gene id: 345632:GPICK_RS06645
uniprot id: A0A0B5B955
names: Similarity
messages: Belongs to the Nudix hydrolase family.

345632:GPICK RS05865
gene id: 345632:GPICK_RS05865
uniprot id: A0A0B5BFW4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

345632:GPICK RS09905
gene id: 345632:GPICK_RS09905
uniprot id: A0A0B5BEP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

345632:GPICK RS05295
gene id: 345632:GPICK_RS05295
uniprot id: A0A0B5B885
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

345632:GPICK RS05830
gene id: 345632:GPICK_RS05830
uniprot id: A0A0B5BFW0
names: Subcellular Location Annotation
messages: Membrane

345632:GPICK RS03615
gene id: 345632:GPICK_RS03615
uniprot id: A0A0B5BC29
names: Subunit
messages: Homodimer.