338966:PPRO RS11870
gene id: 338966:PPRO_RS11870
uniprot id: A1ARN5
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

338966:PPRO RS12985
gene id: 338966:PPRO_RS12985
uniprot id: A1ASB8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS17570
gene id: 338966:PPRO_RS17570
uniprot id: A1AUV3
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS02370
gene id: 338966:PPRO_RS02370
uniprot id: A1AL96
names: Similarity
messages: Belongs to the P(II) protein family.

338966:PPRO RS00085
gene id: 338966:PPRO_RS00085
uniprot id: A1AJY9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

338966:PPRO RS14735
gene id: 338966:PPRO_RS14735
uniprot id: A1AT96
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

338966:PPRO RS02935
gene id: 338966:PPRO_RS02935
uniprot id: A1ALL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

338966:PPRO RS16580
gene id: 338966:PPRO_RS16580
uniprot id: A1AUA0
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

338966:PPRO RS12895
gene id: 338966:PPRO_RS12895
uniprot id: A1AS97
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS11170
gene id: 338966:PPRO_RS11170
uniprot id: A1AR88
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

338966:PPRO RS03140
gene id: 338966:PPRO_RS03140
uniprot id: A1ALQ5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS13815
gene id: 338966:PPRO_RS13815
uniprot id: A1ASR7
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

338966:PPRO RS11880
gene id: 338966:PPRO_RS11880
uniprot id: A1ARN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

338966:PPRO RS02155
gene id: 338966:PPRO_RS02155
uniprot id: A1AL54
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS12110
gene id: 338966:PPRO_RS12110
uniprot id: A1ART2
names: Similarity
messages: Belongs to the YoeB family.

338966:PPRO RS02335
gene id: 338966:PPRO_RS02335
uniprot id: A1AL90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

338966:PPRO RS14885
gene id: 338966:PPRO_RS14885
uniprot id: A1ATC6
names: Similarity
messages: Belongs to the cytochrome c-552 family.

338966:PPRO RS11160
gene id: 338966:PPRO_RS11160
uniprot id: A1AR86
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

338966:PPRO RS06685
gene id: 338966:PPRO_RS06685
uniprot id: A1ANP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS16560
gene id: 338966:PPRO_RS16560
uniprot id: A1AU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338966:PPRO RS06045
gene id: 338966:PPRO_RS06045
uniprot id: A1ANC9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS03455
gene id: 338966:PPRO_RS03455
uniprot id: A1ALW7
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

338966:PPRO RS15345
gene id: 338966:PPRO_RS15345
uniprot id: A1ATL3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

338966:PPRO RS06380
gene id: 338966:PPRO_RS06380
uniprot id: A1ANI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

338966:PPRO RS06115
gene id: 338966:PPRO_RS06115
uniprot id: A1ANE2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

338966:PPRO RS01645
gene id: 338966:PPRO_RS01645
uniprot id: A1AKV3
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS16935
gene id: 338966:PPRO_RS16935
uniprot id: A1AUH6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

338966:PPRO RS09470
gene id: 338966:PPRO_RS09470
uniprot id: A1AQ99
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

338966:PPRO RS03470
gene id: 338966:PPRO_RS03470
uniprot id: A1ALX0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338966:PPRO RS11440
gene id: 338966:PPRO_RS11440
uniprot id: A1ARE6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

338966:PPRO RS15865
gene id: 338966:PPRO_RS15865
uniprot id: A1ALP4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338966:PPRO RS05560
gene id: 338966:PPRO_RS05560
uniprot id: A1AN37
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.
messages: Homodimer.

338966:PPRO RS06910
gene id: 338966:PPRO_RS06910
uniprot id: A1ANT5
names: Similarity
messages: Belongs to the peptidase C56 family.

338966:PPRO RS14385
gene id: 338966:PPRO_RS14385
uniprot id: A1AT28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

338966:PPRO RS13015
gene id: 338966:PPRO_RS13015
uniprot id: A1ASC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

338966:PPRO RS13905
gene id: 338966:PPRO_RS13905
uniprot id: A1AST5
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

338966:PPRO RS03325
gene id: 338966:PPRO_RS03325
uniprot id: A1ALT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

338966:PPRO RS04995
gene id: 338966:PPRO_RS04995
uniprot id: A1AMS8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

338966:PPRO RS00345
gene id: 338966:PPRO_RS00345
uniprot id: A1AK40
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS19135
gene id: 338966:PPRO_RS19135
uniprot id: A0R855
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS11995
gene id: 338966:PPRO_RS11995
uniprot id: A1ARQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

338966:PPRO RS16290
gene id: 338966:PPRO_RS16290
uniprot id: A1AU43
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

338966:PPRO RS06305
gene id: 338966:PPRO_RS06305
uniprot id: A1ANH9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

338966:PPRO RS06025
gene id: 338966:PPRO_RS06025
uniprot id: A1ANC5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12855
gene id: 338966:PPRO_RS12855
uniprot id: A1AS89
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338966:PPRO RS02990
gene id: 338966:PPRO_RS02990
uniprot id: A1ALM6
names: Similarity
messages: Belongs to the CapA family.

338966:PPRO RS17090
gene id: 338966:PPRO_RS17090
uniprot id: A1AUK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

338966:PPRO RS15855
gene id: 338966:PPRO_RS15855
uniprot id: A1ALP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

338966:PPRO RS03330
gene id: 338966:PPRO_RS03330
uniprot id: A1ALT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

338966:PPRO RS03775
gene id: 338966:PPRO_RS03775
uniprot id: A1AM32
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS11850
gene id: 338966:PPRO_RS11850
uniprot id: A1ARN1
names: Similarity
messages: Belongs to the threonine synthase family.

338966:PPRO RS16475
gene id: 338966:PPRO_RS16475
uniprot id: A1AU79
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

338966:PPRO RS03350
gene id: 338966:PPRO_RS03350
uniprot id: A1ALU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

338966:PPRO RS15870
gene id: 338966:PPRO_RS15870
uniprot id: A1ALP3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338966:PPRO RS09740
gene id: 338966:PPRO_RS09740
uniprot id: A1AQF2
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338966:PPRO RS17745
gene id: 338966:PPRO_RS17745
uniprot id: A1AUY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

338966:PPRO RS19375
gene id: 338966:PPRO_RS19375
uniprot id: A1AN66
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS13210
gene id: 338966:PPRO_RS13210
uniprot id: A1ASF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

338966:PPRO RS08310
gene id: 338966:PPRO_RS08310
uniprot id: A1APL5
names: Similarity
messages: Belongs to the leucine-binding protein family.

338966:PPRO RS02220
gene id: 338966:PPRO_RS02220
uniprot id: A1AL66
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338966:PPRO RS12485
gene id: 338966:PPRO_RS12485
uniprot id: A1AS11
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

338966:PPRO RS16045
gene id: 338966:PPRO_RS16045
uniprot id: A1ATZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS13605
gene id: 338966:PPRO_RS13605
uniprot id: A1ASM5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

338966:PPRO RS16830
gene id: 338966:PPRO_RS16830
uniprot id: A1AUF2
names: Similarity
messages: Belongs to the thioredoxin family.

338966:PPRO RS02425
gene id: 338966:PPRO_RS02425
uniprot id: A1ALA7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS03780
gene id: 338966:PPRO_RS03780
uniprot id: A1AM33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

338966:PPRO RS07860
gene id: 338966:PPRO_RS07860
uniprot id: A1APC3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

338966:PPRO RS05520
gene id: 338966:PPRO_RS05520
uniprot id: A1AN29
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS15545
gene id: 338966:PPRO_RS15545
uniprot id: A1ATP9
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

338966:PPRO RS10220
gene id: 338966:PPRO_RS10220
uniprot id: A1AQP8
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

338966:PPRO RS12875
gene id: 338966:PPRO_RS12875
uniprot id: A1AS93
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS07230
gene id: 338966:PPRO_RS07230
uniprot id: A1ANZ9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338966:PPRO RS08595
gene id: 338966:PPRO_RS08595
uniprot id: A1APR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS13370
gene id: 338966:PPRO_RS13370
uniprot id: A1ASI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS09395
gene id: 338966:PPRO_RS09395
uniprot id: A1AQ80
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS15830
gene id: 338966:PPRO_RS15830
uniprot id: A1ALQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

338966:PPRO RS18425
gene id: 338966:PPRO_RS18425
uniprot id: A0R7Y6
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

338966:PPRO RS03235
gene id: 338966:PPRO_RS03235
uniprot id: A1ALS4
names: Similarity
messages: Belongs to the Nth/MutY family.

338966:PPRO RS05280
gene id: 338966:PPRO_RS05280
uniprot id: A1AMY4
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

338966:PPRO RS06675
gene id: 338966:PPRO_RS06675
uniprot id: A1ANP5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

338966:PPRO RS15815
gene id: 338966:PPRO_RS15815
uniprot id: A1ATV1
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS14380
gene id: 338966:PPRO_RS14380
uniprot id: A1AT27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338966:PPRO RS14820
gene id: 338966:PPRO_RS14820
uniprot id: A1ATB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

338966:PPRO RS08510
gene id: 338966:PPRO_RS08510
uniprot id: A1APP8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS17505
gene id: 338966:PPRO_RS17505
uniprot id: A1AUU0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338966:PPRO RS12535
gene id: 338966:PPRO_RS12535
uniprot id: A1AS21
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

338966:PPRO RS10655
gene id: 338966:PPRO_RS10655
uniprot id: A1AQY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

338966:PPRO RS03435
gene id: 338966:PPRO_RS03435
uniprot id: A1ALW3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

338966:PPRO RS11430
gene id: 338966:PPRO_RS11430
uniprot id: A1ARE5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS07340
gene id: 338966:PPRO_RS07340
uniprot id: A1AP20
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338966:PPRO RS10650
gene id: 338966:PPRO_RS10650
uniprot id: A1AQY3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

338966:PPRO RS03040
gene id: 338966:PPRO_RS03040
uniprot id: A1ALN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

338966:PPRO RS17150
gene id: 338966:PPRO_RS17150
uniprot id: A1AUM0
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

338966:PPRO RS06500
gene id: 338966:PPRO_RS06500
uniprot id: A1ANL2
names: Function
names: Similarity
messages: Belongs to the CowN family.
messages: Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.

338966:PPRO RS18390
gene id: 338966:PPRO_RS18390
uniprot id: A0R7Z4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338966:PPRO RS00620
gene id: 338966:PPRO_RS00620
uniprot id: A1AK94
names: Similarity
messages: Belongs to the CFA/CMAS family.

338966:PPRO RS07830
gene id: 338966:PPRO_RS07830
uniprot id: A1APB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

338966:PPRO RS17115
gene id: 338966:PPRO_RS17115
uniprot id: A1AUL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

338966:PPRO RS01130
gene id: 338966:PPRO_RS01130
uniprot id: A1AKK2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

338966:PPRO RS03645
gene id: 338966:PPRO_RS03645
uniprot id: A1AM04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

338966:PPRO RS15825
gene id: 338966:PPRO_RS15825
uniprot id: A1ATV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS09560
gene id: 338966:PPRO_RS09560
uniprot id: A1ALN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

338966:PPRO RS16280
gene id: 338966:PPRO_RS16280
uniprot id: A1AU41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

338966:PPRO RS03385
gene id: 338966:PPRO_RS03385
uniprot id: A1ALV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

338966:PPRO RS02930
gene id: 338966:PPRO_RS02930
uniprot id: A1ALL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

338966:PPRO RS17165
gene id: 338966:PPRO_RS17165
uniprot id: A1AUM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

338966:PPRO RS11885
gene id: 338966:PPRO_RS11885
uniprot id: A1ARN8
names: Similarity
messages: Belongs to the YicC/YloC family.

338966:PPRO RS03985
gene id: 338966:PPRO_RS03985
uniprot id: A1AM74
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS02870
gene id: 338966:PPRO_RS02870
uniprot id: A1ALK2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS02635
gene id: 338966:PPRO_RS02635
uniprot id: A1ALE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

338966:PPRO RS14660
gene id: 338966:PPRO_RS14660
uniprot id: A1AT81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS05925
gene id: 338966:PPRO_RS05925
uniprot id: A1ANA4
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338966:PPRO RS04085
gene id: 338966:PPRO_RS04085
uniprot id: A1AM93
names: Similarity
messages: Belongs to the UPF0166 family.

338966:PPRO RS17135
gene id: 338966:PPRO_RS17135
uniprot id: A1AUL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

338966:PPRO RS06980
gene id: 338966:PPRO_RS06980
uniprot id: A1ANV0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

338966:PPRO RS14865
gene id: 338966:PPRO_RS14865
uniprot id: A1ATC2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS13565
gene id: 338966:PPRO_RS13565
uniprot id: A1ASL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

338966:PPRO RS05030
gene id: 338966:PPRO_RS05030
uniprot id: A1AMT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

338966:PPRO RS12685
gene id: 338966:PPRO_RS12685
uniprot id: A1AS53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

338966:PPRO RS08885
gene id: 338966:PPRO_RS08885
uniprot id: A1APX6
names: Similarity
messages: Belongs to the creatininase superfamily.

338966:PPRO RS01515
gene id: 338966:PPRO_RS01515
uniprot id: A1AKS8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338966:PPRO RS10615
gene id: 338966:PPRO_RS10615
uniprot id: A1AQX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS10085
gene id: 338966:PPRO_RS10085
uniprot id: A1AQM0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338966:PPRO RS02100
gene id: 338966:PPRO_RS02100
uniprot id: A1AL43
names: Similarity
messages: Belongs to the DEAD box helicase family.

338966:PPRO RS19050
gene id: 338966:PPRO_RS19050
uniprot id: A0R854
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15160
gene id: 338966:PPRO_RS15160
uniprot id: A1ATH8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

338966:PPRO RS07465
gene id: 338966:PPRO_RS07465
uniprot id: A1AP46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

338966:PPRO RS11875
gene id: 338966:PPRO_RS11875
uniprot id: A1ARN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338966:PPRO RS02765
gene id: 338966:PPRO_RS02765
uniprot id: A1ALH7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

338966:PPRO RS06035
gene id: 338966:PPRO_RS06035
uniprot id: A1ANC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiM family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

338966:PPRO RS15335
gene id: 338966:PPRO_RS15335
uniprot id: A1ATL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

338966:PPRO RS02280
gene id: 338966:PPRO_RS02280
uniprot id: A1AL79
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

338966:PPRO RS17510
gene id: 338966:PPRO_RS17510
uniprot id: A1AUU1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

338966:PPRO RS14310
gene id: 338966:PPRO_RS14310
uniprot id: A1AT13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338966:PPRO RS17965
gene id: 338966:PPRO_RS17965
uniprot id: A1AV33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

338966:PPRO RS08115
gene id: 338966:PPRO_RS08115
uniprot id: A1ALP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

338966:PPRO RS12770
gene id: 338966:PPRO_RS12770
uniprot id: A1AS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Membrane

338966:PPRO RS21310
gene id: 338966:PPRO_RS21310
uniprot id: A1AU58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

338966:PPRO RS16245
gene id: 338966:PPRO_RS16245
uniprot id: A1AU34
names: Similarity
messages: Belongs to the DapB family.

338966:PPRO RS17170
gene id: 338966:PPRO_RS17170
uniprot id: A1AUM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

338966:PPRO RS12620
gene id: 338966:PPRO_RS12620
uniprot id: A1AS39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

338966:PPRO RS04135
gene id: 338966:PPRO_RS04135
uniprot id: A1AMA3
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338966:PPRO RS06235
gene id: 338966:PPRO_RS06235
uniprot id: A1ANG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338966:PPRO RS01445
gene id: 338966:PPRO_RS01445
uniprot id: A1AKR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

338966:PPRO RS04370
gene id: 338966:PPRO_RS04370
uniprot id: A1AMF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338966:PPRO RS04025
gene id: 338966:PPRO_RS04025
uniprot id: A1AM82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

338966:PPRO RS06410
gene id: 338966:PPRO_RS06410
uniprot id: A1ANJ4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

338966:PPRO RS18395
gene id: 338966:PPRO_RS18395
uniprot id: A0R7Z5
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS04005
gene id: 338966:PPRO_RS04005
uniprot id: A1AM78
names: Similarity
messages: Belongs to the bacterial secretin family.

338966:PPRO RS07870
gene id: 338966:PPRO_RS07870
uniprot id: A1APC5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

338966:PPRO RS15150
gene id: 338966:PPRO_RS15150
uniprot id: A1ATH5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

338966:PPRO RS03035
gene id: 338966:PPRO_RS03035
uniprot id: A1ALN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

338966:PPRO RS12840
gene id: 338966:PPRO_RS12840
uniprot id: A1AS86
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

338966:PPRO RS03050
gene id: 338966:PPRO_RS03050
uniprot id: A1ALN7
names: Similarity
messages: Belongs to the LarC family.

338966:PPRO RS11975
gene id: 338966:PPRO_RS11975
uniprot id: A1ARQ5
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS16155
gene id: 338966:PPRO_RS16155
uniprot id: A1AU17
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

338966:PPRO RS17095
gene id: 338966:PPRO_RS17095
uniprot id: A1AUK9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

338966:PPRO RS07500
gene id: 338966:PPRO_RS07500
uniprot id: A1AP53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

338966:PPRO RS16870
gene id: 338966:PPRO_RS16870
uniprot id: A1AUG0
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

338966:PPRO RS17250
gene id: 338966:PPRO_RS17250
uniprot id: A1AUN9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the NifH/BchL/ChlL family.
messages: Binds 1 [4Fe-4S] cluster per dimer.
messages: Homodimer.
messages: The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
messages: The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.
messages: The reversible ADP-ribosylation of Arg-99 inactivates the nitrogenase reductase and regulates nitrogenase activity.

338966:PPRO RS10080
gene id: 338966:PPRO_RS10080
uniprot id: A1AQL9
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS12410
gene id: 338966:PPRO_RS12410
uniprot id: A1ARZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338966:PPRO RS04935
gene id: 338966:PPRO_RS04935
uniprot id: A0R7X9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

338966:PPRO RS06460
gene id: 338966:PPRO_RS06460
uniprot id: A1ANK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338966:PPRO RS15100
gene id: 338966:PPRO_RS15100
uniprot id: A1ATH0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

338966:PPRO RS16335
gene id: 338966:PPRO_RS16335
uniprot id: A1AU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

338966:PPRO RS02275
gene id: 338966:PPRO_RS02275
uniprot id: A1AL78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

338966:PPRO RS00010
gene id: 338966:PPRO_RS00010
uniprot id: A1AJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

338966:PPRO RS10635
gene id: 338966:PPRO_RS10635
uniprot id: A1AQY0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

338966:PPRO RS13065
gene id: 338966:PPRO_RS13065
uniprot id: A1ASD4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

338966:PPRO RS06225
gene id: 338966:PPRO_RS06225
uniprot id: A1ANG3
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

338966:PPRO RS14985
gene id: 338966:PPRO_RS14985
uniprot id: A1ATE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

338966:PPRO RS19775
gene id: 338966:PPRO_RS19775
uniprot id: A1ATZ0
names: Similarity
messages: Belongs to the FlgM family.

338966:PPRO RS14325
gene id: 338966:PPRO_RS14325
uniprot id: A1AT16
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338966:PPRO RS16400
gene id: 338966:PPRO_RS16400
uniprot id: A1AU65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

338966:PPRO RS16215
gene id: 338966:PPRO_RS16215
uniprot id: A1AU29
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

338966:PPRO RS07295
gene id: 338966:PPRO_RS07295
uniprot id: A1AP11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338966:PPRO RS15330
gene id: 338966:PPRO_RS15330
uniprot id: A1ATL0
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

338966:PPRO RS08655
gene id: 338966:PPRO_RS08655
uniprot id: A1APS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

338966:PPRO RS02160
gene id: 338966:PPRO_RS02160
uniprot id: A1AL55
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

338966:PPRO RS07725
gene id: 338966:PPRO_RS07725
uniprot id: A1AP96
names: Similarity
messages: Belongs to the xanthine dehydrogenase family.

338966:PPRO RS14765
gene id: 338966:PPRO_RS14765
uniprot id: A1ATA2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

338966:PPRO RS13135
gene id: 338966:PPRO_RS13135
uniprot id: A1ASE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338966:PPRO RS01630
gene id: 338966:PPRO_RS01630
uniprot id: A1AKV0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS18420
gene id: 338966:PPRO_RS18420
uniprot id: A0R7Y5
names: Similarity
messages: Belongs to the cytochrome c-552 family.

338966:PPRO RS08220
gene id: 338966:PPRO_RS08220
uniprot id: A1APJ5
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

338966:PPRO RS09810
gene id: 338966:PPRO_RS09810
uniprot id: A1AQG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS18470
gene id: 338966:PPRO_RS18470
uniprot id: A0R7X9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

338966:PPRO RS16375
gene id: 338966:PPRO_RS16375
uniprot id: A1AU60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

338966:PPRO RS12280
gene id: 338966:PPRO_RS12280
uniprot id: A1ARW9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

338966:PPRO RS10390
gene id: 338966:PPRO_RS10390
uniprot id: A1AQT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

338966:PPRO RS21305
gene id: 338966:PPRO_RS21305
uniprot id: A1AU57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

338966:PPRO RS17865
gene id: 338966:PPRO_RS17865
uniprot id: A1AV12
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

338966:PPRO RS03335
gene id: 338966:PPRO_RS03335
uniprot id: A1ALS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

338966:PPRO RS17590
gene id: 338966:PPRO_RS17590
uniprot id: A1AUV7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

338966:PPRO RS02510
gene id: 338966:PPRO_RS02510
uniprot id: A1ALC4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

338966:PPRO RS02890
gene id: 338966:PPRO_RS02890
uniprot id: A1ALK6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

338966:PPRO RS08605
gene id: 338966:PPRO_RS08605
uniprot id: A1APR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS00015
gene id: 338966:PPRO_RS00015
uniprot id: A1AJX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

338966:PPRO RS17470
gene id: 338966:PPRO_RS17470
uniprot id: A1AUT3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

338966:PPRO RS04815
gene id: 338966:PPRO_RS04815
uniprot id: A1AMP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm

338966:PPRO RS12635
gene id: 338966:PPRO_RS12635
uniprot id: A1AS42
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

338966:PPRO RS19115
gene id: 338966:PPRO_RS19115
uniprot id: A0R851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338966:PPRO RS06705
gene id: 338966:PPRO_RS06705
uniprot id: A1ANQ1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS04260
gene id: 338966:PPRO_RS04260
uniprot id: A1AMC8
names: Function
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

338966:PPRO RS07560
gene id: 338966:PPRO_RS07560
uniprot id: A1AP65
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

338966:PPRO RS12300
gene id: 338966:PPRO_RS12300
uniprot id: A1ARX3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

338966:PPRO RS08455
gene id: 338966:PPRO_RS08455
uniprot id: A1APN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338966:PPRO RS17900
gene id: 338966:PPRO_RS17900
uniprot id: A1AV19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

338966:PPRO RS17155
gene id: 338966:PPRO_RS17155
uniprot id: A1AUM1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

338966:PPRO RS00205
gene id: 338966:PPRO_RS00205
uniprot id: A1AK12
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS05625
gene id: 338966:PPRO_RS05625
uniprot id: A1AN51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

338966:PPRO RS17365
gene id: 338966:PPRO_RS17365
uniprot id: A1AUR1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

338966:PPRO RS02625
gene id: 338966:PPRO_RS02625
uniprot id: A1ALE6
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS08920
gene id: 338966:PPRO_RS08920
uniprot id: A1APY3
names: Similarity
messages: Belongs to the YjdM family.

338966:PPRO RS06100
gene id: 338966:PPRO_RS06100
uniprot id: A1AND9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338966:PPRO RS12590
gene id: 338966:PPRO_RS12590
uniprot id: A1AS33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

338966:PPRO RS14435
gene id: 338966:PPRO_RS14435
uniprot id: A1AT38
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338966:PPRO RS14710
gene id: 338966:PPRO_RS14710
uniprot id: A1AT91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

338966:PPRO RS00540
gene id: 338966:PPRO_RS00540
uniprot id: A0R7X9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

338966:PPRO RS16020
gene id: 338966:PPRO_RS16020
uniprot id: A1ATZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338966:PPRO RS03650
gene id: 338966:PPRO_RS03650
uniprot id: A1AM05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

338966:PPRO RS16940
gene id: 338966:PPRO_RS16940
uniprot id: A1AUH7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS03830
gene id: 338966:PPRO_RS03830
uniprot id: A1AM43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

338966:PPRO RS11195
gene id: 338966:PPRO_RS11195
uniprot id: A1AR93
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

338966:PPRO RS02000
gene id: 338966:PPRO_RS02000
uniprot id: A1AL25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS02730
gene id: 338966:PPRO_RS02730
uniprot id: A1ALH0
names: Similarity
messages: Belongs to the MlaA family.

338966:PPRO RS16140
gene id: 338966:PPRO_RS16140
uniprot id: A1AU14
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

338966:PPRO RS03670
gene id: 338966:PPRO_RS03670
uniprot id: A1AM09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

338966:PPRO RS00875
gene id: 338966:PPRO_RS00875
uniprot id: A1AKE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

338966:PPRO RS16455
gene id: 338966:PPRO_RS16455
uniprot id: A1AU75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

338966:PPRO RS03085
gene id: 338966:PPRO_RS03085
uniprot id: A1ALP4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338966:PPRO RS08335
gene id: 338966:PPRO_RS08335
uniprot id: A1APM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

338966:PPRO RS03115
gene id: 338966:PPRO_RS03115
uniprot id: A1ALQ0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14470
gene id: 338966:PPRO_RS14470
uniprot id: A1AT45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS16540
gene id: 338966:PPRO_RS16540
uniprot id: A1AU93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS01085
gene id: 338966:PPRO_RS01085
uniprot id: A1AKJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

338966:PPRO RS15170
gene id: 338966:PPRO_RS15170
uniprot id: A1ATI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

338966:PPRO RS03315
gene id: 338966:PPRO_RS03315
uniprot id: A1ALT5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338966:PPRO RS18050
gene id: 338966:PPRO_RS18050
uniprot id: A0R7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

338966:PPRO RS14330
gene id: 338966:PPRO_RS14330
uniprot id: A1AT17
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

338966:PPRO RS04145
gene id: 338966:PPRO_RS04145
uniprot id: A1AMA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

338966:PPRO RS03120
gene id: 338966:PPRO_RS03120
uniprot id: A1ALQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

338966:PPRO RS08070
gene id: 338966:PPRO_RS08070
uniprot id: A1APG6
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12900
gene id: 338966:PPRO_RS12900
uniprot id: A1AS98
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12315
gene id: 338966:PPRO_RS12315
uniprot id: A1ARX6
names: Similarity
messages: Belongs to the ros/MucR family.

338966:PPRO RS06885
gene id: 338966:PPRO_RS06885
uniprot id: A1ANT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS01590
gene id: 338966:PPRO_RS01590
uniprot id: A1AKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338966:PPRO RS14150
gene id: 338966:PPRO_RS14150
uniprot id: A0R7X9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

338966:PPRO RS00640
gene id: 338966:PPRO_RS00640
uniprot id: A1AK98
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS06630
gene id: 338966:PPRO_RS06630
uniprot id: A1ANN6
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

338966:PPRO RS01855
gene id: 338966:PPRO_RS01855
uniprot id: A1AKZ4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

338966:PPRO RS08630
gene id: 338966:PPRO_RS08630
uniprot id: A1APS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

338966:PPRO RS03410
gene id: 338966:PPRO_RS03410
uniprot id: A1ALV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

338966:PPRO RS12495
gene id: 338966:PPRO_RS12495
uniprot id: A1AS13
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

338966:PPRO RS10730
gene id: 338966:PPRO_RS10730
uniprot id: A1AQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

338966:PPRO RS08320
gene id: 338966:PPRO_RS08320
uniprot id: A1APL7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08745
gene id: 338966:PPRO_RS08745
uniprot id: A1APU8
names: Similarity
messages: Belongs to the plasmid replication initiation factor family.

338966:PPRO RS04275
gene id: 338966:PPRO_RS04275
uniprot id: A1AMD1
names: Similarity
messages: Belongs to the transglycosylase Slt family.

338966:PPRO RS17025
gene id: 338966:PPRO_RS17025
uniprot id: A1AUJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

338966:PPRO RS08540
gene id: 338966:PPRO_RS08540
uniprot id: A1APQ5
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

338966:PPRO RS00035
gene id: 338966:PPRO_RS00035
uniprot id: A1AJX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

338966:PPRO RS13240
gene id: 338966:PPRO_RS13240
uniprot id: A1ASG0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS05760
gene id: 338966:PPRO_RS05760
uniprot id: A1AN78
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS11890
gene id: 338966:PPRO_RS11890
uniprot id: A1ARN9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

338966:PPRO RS19365
gene id: 338966:PPRO_RS19365
uniprot id: A1AN42
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS06540
gene id: 338966:PPRO_RS06540
uniprot id: A0R7X9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

338966:PPRO RS18810
gene id: 338966:PPRO_RS18810
uniprot id: A0R7R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm

338966:PPRO RS08680
gene id: 338966:PPRO_RS08680
uniprot id: A1APT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

338966:PPRO RS02945
gene id: 338966:PPRO_RS02945
uniprot id: A1ALL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338966:PPRO RS14925
gene id: 338966:PPRO_RS14925
uniprot id: A1ATD4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

338966:PPRO RS11225
gene id: 338966:PPRO_RS11225
uniprot id: A1AR99
names: Similarity
messages: Belongs to the aspartokinase family.

338966:PPRO RS12320
gene id: 338966:PPRO_RS12320
uniprot id: A1ARX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

338966:PPRO RS08185
gene id: 338966:PPRO_RS08185
uniprot id: A1API8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS08870
gene id: 338966:PPRO_RS08870
uniprot id: A1APX3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS03365
gene id: 338966:PPRO_RS03365
uniprot id: A1ALU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

338966:PPRO RS00130
gene id: 338966:PPRO_RS00130
uniprot id: A1AJZ6
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS11070
gene id: 338966:PPRO_RS11070
uniprot id: A1AR69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

338966:PPRO RS06425
gene id: 338966:PPRO_RS06425
uniprot id: A1ANJ7
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

338966:PPRO RS00930
gene id: 338966:PPRO_RS00930
uniprot id: A1AKF5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

338966:PPRO RS13070
gene id: 338966:PPRO_RS13070
uniprot id: A1ASD5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS12060
gene id: 338966:PPRO_RS12060
uniprot id: A1ARS2
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

338966:PPRO RS15720
gene id: 338966:PPRO_RS15720
uniprot id: A1ATT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

338966:PPRO RS10835
gene id: 338966:PPRO_RS10835
uniprot id: A1AR20
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS08775
gene id: 338966:PPRO_RS08775
uniprot id: A1APV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

338966:PPRO RS00945
gene id: 338966:PPRO_RS00945
uniprot id: A1AKF8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

338966:PPRO RS03190
gene id: 338966:PPRO_RS03190
uniprot id: A1ALR5
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS18315
gene id: 338966:PPRO_RS18315
uniprot id: A0R806
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

338966:PPRO RS16165
gene id: 338966:PPRO_RS16165
uniprot id: A1AU19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338966:PPRO RS02850
gene id: 338966:PPRO_RS02850
uniprot id: A1ALJ8
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS10170
gene id: 338966:PPRO_RS10170
uniprot id: A1AQN8
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

338966:PPRO RS03990
gene id: 338966:PPRO_RS03990
uniprot id: A1AM75
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS00455
gene id: 338966:PPRO_RS00455
uniprot id: A1AK60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

338966:PPRO RS06265
gene id: 338966:PPRO_RS06265
uniprot id: A1ANH1
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

338966:PPRO RS06915
gene id: 338966:PPRO_RS06915
uniprot id: A1ANT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

338966:PPRO RS09975
gene id: 338966:PPRO_RS09975
uniprot id: A1AQJ8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

338966:PPRO RS12965
gene id: 338966:PPRO_RS12965
uniprot id: A1ASB4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

338966:PPRO RS12565
gene id: 338966:PPRO_RS12565
uniprot id: A1AS28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

338966:PPRO RS18440
gene id: 338966:PPRO_RS18440
uniprot id: A0R7Z0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338966:PPRO RS14070
gene id: 338966:PPRO_RS14070
uniprot id: A1ASW7
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

338966:PPRO RS10625
gene id: 338966:PPRO_RS10625
uniprot id: A1AQX7
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

338966:PPRO RS17465
gene id: 338966:PPRO_RS17465
uniprot id: A1AUT1
names: Cofactor
messages: Binds 4 heme c groups covalently per monomer.

338966:PPRO RS09285
gene id: 338966:PPRO_RS09285
uniprot id: A1AQ57
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

338966:PPRO RS09495
gene id: 338966:PPRO_RS09495
uniprot id: A0R850
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS06890
gene id: 338966:PPRO_RS06890
uniprot id: A1ANT1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

338966:PPRO RS10305
gene id: 338966:PPRO_RS10305
uniprot id: A1AQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS02060
gene id: 338966:PPRO_RS02060
uniprot id: A1AL36
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

338966:PPRO RS19175
gene id: 338966:PPRO_RS19175
uniprot id: A1AK25
names: Similarity
messages: Belongs to the Fmt family.

338966:PPRO RS04800
gene id: 338966:PPRO_RS04800
uniprot id: A1AMP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

338966:PPRO RS10855
gene id: 338966:PPRO_RS10855
uniprot id: A1AR24
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS19130
gene id: 338966:PPRO_RS19130
uniprot id: A0R854
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS01385
gene id: 338966:PPRO_RS01385
uniprot id: A1AKQ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS19505
gene id: 338966:PPRO_RS19505
uniprot id: A1AQG0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17830
gene id: 338966:PPRO_RS17830
uniprot id: A1AV05
names: Similarity
messages: Belongs to the UPF0111 family.

338966:PPRO RS11500
gene id: 338966:PPRO_RS11500
uniprot id: A1ARF8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

338966:PPRO RS06625
gene id: 338966:PPRO_RS06625
uniprot id: A1ANN5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

338966:PPRO RS10415
gene id: 338966:PPRO_RS10415
uniprot id: A1AQT6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

338966:PPRO RS04635
gene id: 338966:PPRO_RS04635
uniprot id: A1AMK6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

338966:PPRO RS06900
gene id: 338966:PPRO_RS06900
uniprot id: A1ANT3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

338966:PPRO RS12645
gene id: 338966:PPRO_RS12645
uniprot id: A1AS44
names: Similarity
messages: Belongs to the TPP enzyme family.

338966:PPRO RS02495
gene id: 338966:PPRO_RS02495
uniprot id: A1ALC1
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

338966:PPRO RS07675
gene id: 338966:PPRO_RS07675
uniprot id: A1AP86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS08080
gene id: 338966:PPRO_RS08080
uniprot id: A1ALN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

338966:PPRO RS01520
gene id: 338966:PPRO_RS01520
uniprot id: A1AKS9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338966:PPRO RS14205
gene id: 338966:PPRO_RS14205
uniprot id: A1ASZ2
names: Similarity
messages: Belongs to the FemABX family.

338966:PPRO RS14520
gene id: 338966:PPRO_RS14520
uniprot id: A1AT55
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS11165
gene id: 338966:PPRO_RS11165
uniprot id: A1AR87
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS01895
gene id: 338966:PPRO_RS01895
uniprot id: A1AL03
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

338966:PPRO RS17820
gene id: 338966:PPRO_RS17820
uniprot id: A1AV03
names: Similarity
messages: Belongs to the UPF0758 family.

338966:PPRO RS14650
gene id: 338966:PPRO_RS14650
uniprot id: A1AT79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338966:PPRO RS08960
gene id: 338966:PPRO_RS08960
uniprot id: A1APZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

338966:PPRO RS12640
gene id: 338966:PPRO_RS12640
uniprot id: A1AS43
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

338966:PPRO RS09445
gene id: 338966:PPRO_RS09445
uniprot id: A1AQ94
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

338966:PPRO RS16285
gene id: 338966:PPRO_RS16285
uniprot id: A1AU42
names: Function
names: Similarity
messages: Belongs to the trehalose phosphatase family.
messages: Removes the phosphate from trehalose 6-phosphate to produce free trehalose.

338966:PPRO RS16600
gene id: 338966:PPRO_RS16600
uniprot id: A1AUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

338966:PPRO RS03615
gene id: 338966:PPRO_RS03615
uniprot id: A1ALZ9
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

338966:PPRO RS02950
gene id: 338966:PPRO_RS02950
uniprot id: A1ALL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

338966:PPRO RS09730
gene id: 338966:PPRO_RS09730
uniprot id: A1AQF0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS11155
gene id: 338966:PPRO_RS11155
uniprot id: A1AR85
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

338966:PPRO RS13800
gene id: 338966:PPRO_RS13800
uniprot id: A1ASR4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS05850
gene id: 338966:PPRO_RS05850
uniprot id: A1AN93
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

338966:PPRO RS07930
gene id: 338966:PPRO_RS07930
uniprot id: A1APD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

338966:PPRO RS03320
gene id: 338966:PPRO_RS03320
uniprot id: A1ALT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

338966:PPRO RS02055
gene id: 338966:PPRO_RS02055
uniprot id: A1AL35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

338966:PPRO RS16315
gene id: 338966:PPRO_RS16315
uniprot id: A1AU48
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

338966:PPRO RS18460
gene id: 338966:PPRO_RS18460
uniprot id: A0R7X7
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS17825
gene id: 338966:PPRO_RS17825
uniprot id: A1AV04
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

338966:PPRO RS02585
gene id: 338966:PPRO_RS02585
uniprot id: A1ALD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

338966:PPRO RS10110
gene id: 338966:PPRO_RS10110
uniprot id: A1AQM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS03065
gene id: 338966:PPRO_RS03065
uniprot id: A1ALP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

338966:PPRO RS07300
gene id: 338966:PPRO_RS07300
uniprot id: A1AP12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338966:PPRO RS06420
gene id: 338966:PPRO_RS06420
uniprot id: A1ANJ6
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

338966:PPRO RS00155
gene id: 338966:PPRO_RS00155
uniprot id: A1AK01
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS10155
gene id: 338966:PPRO_RS10155
uniprot id: A1AQN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

338966:PPRO RS02995
gene id: 338966:PPRO_RS02995
uniprot id: A1ALM7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

338966:PPRO RS07025
gene id: 338966:PPRO_RS07025
uniprot id: A1ANV9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

338966:PPRO RS15835
gene id: 338966:PPRO_RS15835
uniprot id: A1ALQ0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS06860
gene id: 338966:PPRO_RS06860
uniprot id: A1ANS5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS03370
gene id: 338966:PPRO_RS03370
uniprot id: A1ALU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

338966:PPRO RS05305
gene id: 338966:PPRO_RS05305
uniprot id: A1AMY9
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS12550
gene id: 338966:PPRO_RS12550
uniprot id: A1AS25
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

338966:PPRO RS03285
gene id: 338966:PPRO_RS03285
uniprot id: A1ALS9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

338966:PPRO RS08295
gene id: 338966:PPRO_RS08295
uniprot id: A1APL2
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

338966:PPRO RS03375
gene id: 338966:PPRO_RS03375
uniprot id: A1ALU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

338966:PPRO RS16500
gene id: 338966:PPRO_RS16500
uniprot id: A1AU84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

338966:PPRO RS08995
gene id: 338966:PPRO_RS08995
uniprot id: A1APZ8
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS02360
gene id: 338966:PPRO_RS02360
uniprot id: A1AL94
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

338966:PPRO RS12815
gene id: 338966:PPRO_RS12815
uniprot id: A1AS80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

338966:PPRO RS15960
gene id: 338966:PPRO_RS15960
uniprot id: A1ATY0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338966:PPRO RS04760
gene id: 338966:PPRO_RS04760
uniprot id: A1AMN2
names: Similarity
messages: Belongs to the sigma-54 factor family.

338966:PPRO RS09995
gene id: 338966:PPRO_RS09995
uniprot id: A1AQK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS16210
gene id: 338966:PPRO_RS16210
uniprot id: A1AU28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

338966:PPRO RS17645
gene id: 338966:PPRO_RS17645
uniprot id: A1AUW9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS04210
gene id: 338966:PPRO_RS04210
uniprot id: A1AMB8
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS06325
gene id: 338966:PPRO_RS06325
uniprot id: A1ANI3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

338966:PPRO RS01510
gene id: 338966:PPRO_RS01510
uniprot id: A1AKS7
names: Similarity
messages: Belongs to the UPF0047 family.

338966:PPRO RS00025
gene id: 338966:PPRO_RS00025
uniprot id: A1AJX6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

338966:PPRO RS02845
gene id: 338966:PPRO_RS02845
uniprot id: A1ALJ5
names: Similarity
messages: Belongs to the ParB family.

338966:PPRO RS16670
gene id: 338966:PPRO_RS16670
uniprot id: A1AUB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

338966:PPRO RS03310
gene id: 338966:PPRO_RS03310
uniprot id: A1ALT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338966:PPRO RS07185
gene id: 338966:PPRO_RS07185
uniprot id: A1ANY9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS11905
gene id: 338966:PPRO_RS11905
uniprot id: A1ARP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

338966:PPRO RS08365
gene id: 338966:PPRO_RS08365
uniprot id: A1APM6
names: Similarity
messages: Belongs to the glutamine synthetase family.

338966:PPRO RS02270
gene id: 338966:PPRO_RS02270
uniprot id: A1AL77
names: Similarity
messages: Belongs to the AOR/FOR family.

338966:PPRO RS02910
gene id: 338966:PPRO_RS02910
uniprot id: A1ALL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

338966:PPRO RS18375
gene id: 338966:PPRO_RS18375
uniprot id: A0R804
names: Similarity
messages: Belongs to the transposase 7 family.

338966:PPRO RS15240
gene id: 338966:PPRO_RS15240
uniprot id: A1ATJ1
names: Similarity
messages: Belongs to the SAICAR synthetase family.

338966:PPRO RS16355
gene id: 338966:PPRO_RS16355
uniprot id: A1AU56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

338966:PPRO RS06400
gene id: 338966:PPRO_RS06400
uniprot id: A1ANJ2
names: Similarity
messages: Belongs to the TrpF family.

338966:PPRO RS04500
gene id: 338966:PPRO_RS04500
uniprot id: A1AMH6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338966:PPRO RS02450
gene id: 338966:PPRO_RS02450
uniprot id: A1ALB2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

338966:PPRO RS08040
gene id: 338966:PPRO_RS08040
uniprot id: A1APF9
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

338966:PPRO RS16925
gene id: 338966:PPRO_RS16925
uniprot id: A1AUH4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15985
gene id: 338966:PPRO_RS15985
uniprot id: A1ATY5
names: Subcellular Location Annotation
messages: Nucleus

338966:PPRO RS12810
gene id: 338966:PPRO_RS12810
uniprot id: A1AS79
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

338966:PPRO RS15440
gene id: 338966:PPRO_RS15440
uniprot id: A1ATN0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS12625
gene id: 338966:PPRO_RS12625
uniprot id: A1AS40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

338966:PPRO RS17430
gene id: 338966:PPRO_RS17430
uniprot id: A1AUS4
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338966:PPRO RS17420
gene id: 338966:PPRO_RS17420
uniprot id: A1AUS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

338966:PPRO RS14085
gene id: 338966:PPRO_RS14085
uniprot id: A1ASX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

338966:PPRO RS08485
gene id: 338966:PPRO_RS08485
uniprot id: A1APP4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

338966:PPRO RS14015
gene id: 338966:PPRO_RS14015
uniprot id: A1ASV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

338966:PPRO RS00885
gene id: 338966:PPRO_RS00885
uniprot id: A1AKE6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS08445
gene id: 338966:PPRO_RS08445
uniprot id: A1APN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS14625
gene id: 338966:PPRO_RS14625
uniprot id: A1AT74
names: Similarity
messages: Belongs to the HepT RNase toxin family.

338966:PPRO RS11980
gene id: 338966:PPRO_RS11980
uniprot id: A1ARQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS03485
gene id: 338966:PPRO_RS03485
uniprot id: A1ALX3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

338966:PPRO RS14965
gene id: 338966:PPRO_RS14965
uniprot id: A1ATE2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS05380
gene id: 338966:PPRO_RS05380
uniprot id: A1AN04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

338966:PPRO RS06875
gene id: 338966:PPRO_RS06875
uniprot id: A1ANS8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

338966:PPRO RS08470
gene id: 338966:PPRO_RS08470
uniprot id: A1APP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

338966:PPRO RS09225
gene id: 338966:PPRO_RS09225
uniprot id: A1AQ46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

338966:PPRO RS17555
gene id: 338966:PPRO_RS17555
uniprot id: A1AUV0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS18905
gene id: 338966:PPRO_RS18905
uniprot id: A0R7T5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS02590
gene id: 338966:PPRO_RS02590
uniprot id: A1ALD9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

338966:PPRO RS18245
gene id: 338966:PPRO_RS18245
uniprot id: A0R822
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

338966:PPRO RS17995
gene id: 338966:PPRO_RS17995
uniprot id: A1AV39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

338966:PPRO RS08145
gene id: 338966:PPRO_RS08145
uniprot id: A1API1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS13180
gene id: 338966:PPRO_RS13180
uniprot id: A1ASE9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS13625
gene id: 338966:PPRO_RS13625
uniprot id: A1ASM9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS13295
gene id: 338966:PPRO_RS13295
uniprot id: A1ASG9
names: Similarity
messages: Belongs to the Lgt family.

338966:PPRO RS08935
gene id: 338966:PPRO_RS08935
uniprot id: A1APY6
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS07470
gene id: 338966:PPRO_RS07470
uniprot id: A1AP47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

338966:PPRO RS02860
gene id: 338966:PPRO_RS02860
uniprot id: A1ALK0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12365
gene id: 338966:PPRO_RS12365
uniprot id: A1ARY7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS04765
gene id: 338966:PPRO_RS04765
uniprot id: A1AMN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

338966:PPRO RS19450
gene id: 338966:PPRO_RS19450
uniprot id: A1ALP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS08660
gene id: 338966:PPRO_RS08660
uniprot id: A1APS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

338966:PPRO RS06105
gene id: 338966:PPRO_RS06105
uniprot id: A1ANE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338966:PPRO RS16840
gene id: 338966:PPRO_RS16840
uniprot id: A1AUF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

338966:PPRO RS16460
gene id: 338966:PPRO_RS16460
uniprot id: A1AU76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

338966:PPRO RS12525
gene id: 338966:PPRO_RS12525
uniprot id: A1AS19
names: Similarity
messages: Belongs to the DEAD box helicase family.

338966:PPRO RS10380
gene id: 338966:PPRO_RS10380
uniprot id: A1AQS9
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

338966:PPRO RS16480
gene id: 338966:PPRO_RS16480
uniprot id: A1AU80
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS11185
gene id: 338966:PPRO_RS11185
uniprot id: A1AR91
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

338966:PPRO RS10145
gene id: 338966:PPRO_RS10145
uniprot id: A1AQN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

338966:PPRO RS15340
gene id: 338966:PPRO_RS15340
uniprot id: A1ATL2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

338966:PPRO RS03665
gene id: 338966:PPRO_RS03665
uniprot id: A1AM08
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

338966:PPRO RS04325
gene id: 338966:PPRO_RS04325
uniprot id: A1AME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

338966:PPRO RS17110
gene id: 338966:PPRO_RS17110
uniprot id: A1AUL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

338966:PPRO RS19155
gene id: 338966:PPRO_RS19155
uniprot id: A0R876
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

338966:PPRO RS08835
gene id: 338966:PPRO_RS08835
uniprot id: A1APW6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

338966:PPRO RS07460
gene id: 338966:PPRO_RS07460
uniprot id: A1AP45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

338966:PPRO RS14880
gene id: 338966:PPRO_RS14880
uniprot id: A1ATC5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS01410
gene id: 338966:PPRO_RS01410
uniprot id: A1AKQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

338966:PPRO RS00050
gene id: 338966:PPRO_RS00050
uniprot id: A1AJY2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

338966:PPRO RS00415
gene id: 338966:PPRO_RS00415
uniprot id: A1AK52
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

338966:PPRO RS16255
gene id: 338966:PPRO_RS16255
uniprot id: A1AU36
names: Similarity
messages: Belongs to the disproportionating enzyme family.

338966:PPRO RS03640
gene id: 338966:PPRO_RS03640
uniprot id: A1AM03
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

338966:PPRO RS16160
gene id: 338966:PPRO_RS16160
uniprot id: A1AU18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

338966:PPRO RS07840
gene id: 338966:PPRO_RS07840
uniprot id: A1APB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

338966:PPRO RS06405
gene id: 338966:PPRO_RS06405
uniprot id: A1ANJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

338966:PPRO RS02345
gene id: 338966:PPRO_RS02345
uniprot id: A1AL91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

338966:PPRO RS19400
gene id: 338966:PPRO_RS19400
uniprot id: A1ANP2
names: Subcellular Location Annotation
messages: Cell inner membrane

338966:PPRO RS00880
gene id: 338966:PPRO_RS00880
uniprot id: A1AKE5
names: Similarity
messages: Belongs to the XseB family.

338966:PPRO RS00985
gene id: 338966:PPRO_RS00985
uniprot id: A1AKG6
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS03080
gene id: 338966:PPRO_RS03080
uniprot id: A1ALP3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338966:PPRO RS15255
gene id: 338966:PPRO_RS15255
uniprot id: A1ATJ4
names: Similarity
messages: Belongs to the peptidase S16 family.

338966:PPRO RS06510
gene id: 338966:PPRO_RS06510
uniprot id: A1ANL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

338966:PPRO RS03305
gene id: 338966:PPRO_RS03305
uniprot id: A1ALT3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

338966:PPRO RS07515
gene id: 338966:PPRO_RS07515
uniprot id: A1AP56
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS09520
gene id: 338966:PPRO_RS09520
uniprot id: A0R855
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS14510
gene id: 338966:PPRO_RS14510
uniprot id: A1AT53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

338966:PPRO RS05605
gene id: 338966:PPRO_RS05605
uniprot id: A1AN46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

338966:PPRO RS04265
gene id: 338966:PPRO_RS04265
uniprot id: A1AMC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.

338966:PPRO RS07480
gene id: 338966:PPRO_RS07480
uniprot id: A1ALL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

338966:PPRO RS00935
gene id: 338966:PPRO_RS00935
uniprot id: A1AKF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

338966:PPRO RS16380
gene id: 338966:PPRO_RS16380
uniprot id: A1AU61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

338966:PPRO RS08060
gene id: 338966:PPRO_RS08060
uniprot id: A1APG3
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

338966:PPRO RS07080
gene id: 338966:PPRO_RS07080
uniprot id: A1ANX0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS09000
gene id: 338966:PPRO_RS09000
uniprot id: A1APZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

338966:PPRO RS17275
gene id: 338966:PPRO_RS17275
uniprot id: A1AUP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

338966:PPRO RS11210
gene id: 338966:PPRO_RS11210
uniprot id: A1AR96
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.

338966:PPRO RS07330
gene id: 338966:PPRO_RS07330
uniprot id: A1AP18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS00220
gene id: 338966:PPRO_RS00220
uniprot id: A1AK15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS12325
gene id: 338966:PPRO_RS12325
uniprot id: A1ARX8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

338966:PPRO RS11445
gene id: 338966:PPRO_RS11445
uniprot id: A1ARE7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

338966:PPRO RS17535
gene id: 338966:PPRO_RS17535
uniprot id: A1AUU6
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

338966:PPRO RS05185
gene id: 338966:PPRO_RS05185
uniprot id: A1AMW5
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS16725
gene id: 338966:PPRO_RS16725
uniprot id: A1AUD1
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338966:PPRO RS09805
gene id: 338966:PPRO_RS09805
uniprot id: A1AQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS05370
gene id: 338966:PPRO_RS05370
uniprot id: A1AN02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

338966:PPRO RS03295
gene id: 338966:PPRO_RS03295
uniprot id: A1ALT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

338966:PPRO RS15890
gene id: 338966:PPRO_RS15890
uniprot id: A1ALN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

338966:PPRO RS17245
gene id: 338966:PPRO_RS17245
uniprot id: A1AUN8
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.
messages: This protein is a Fe-Mo-cofactor biosynthetic component.

338966:PPRO RS10375
gene id: 338966:PPRO_RS10375
uniprot id: A1AQS8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

338966:PPRO RS16305
gene id: 338966:PPRO_RS16305
uniprot id: A1AU46
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

338966:PPRO RS04100
gene id: 338966:PPRO_RS04100
uniprot id: A1AM96
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS04545
gene id: 338966:PPRO_RS04545
uniprot id: A1AMI5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338966:PPRO RS07495
gene id: 338966:PPRO_RS07495
uniprot id: A1AP52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338966:PPRO RS05660
gene id: 338966:PPRO_RS05660
uniprot id: A1AN57
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS14555
gene id: 338966:PPRO_RS14555
uniprot id: A1AT62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

338966:PPRO RS16425
gene id: 338966:PPRO_RS16425
uniprot id: A1AU70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

338966:PPRO RS10270
gene id: 338966:PPRO_RS10270
uniprot id: A1AQQ8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

338966:PPRO RS10740
gene id: 338966:PPRO_RS10740
uniprot id: A1AQZ8
names: Similarity
messages: Belongs to the glutamate synthase family.

338966:PPRO RS03820
gene id: 338966:PPRO_RS03820
uniprot id: A1AM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

338966:PPRO RS07880
gene id: 338966:PPRO_RS07880
uniprot id: A1APC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

338966:PPRO RS05205
gene id: 338966:PPRO_RS05205
uniprot id: A1AMW9
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

338966:PPRO RS15415
gene id: 338966:PPRO_RS15415
uniprot id: A1ATM5
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

338966:PPRO RS07595
gene id: 338966:PPRO_RS07595
uniprot id: A1AP72
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS10980
gene id: 338966:PPRO_RS10980
uniprot id: A1AR49
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

338966:PPRO RS18325
gene id: 338966:PPRO_RS18325
uniprot id: A0R808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338966:PPRO RS00580
gene id: 338966:PPRO_RS00580
uniprot id: A1AK85
names: Similarity
messages: Belongs to the glutathione peroxidase family.

338966:PPRO RS07900
gene id: 338966:PPRO_RS07900
uniprot id: A1APD2
names: Similarity
messages: Belongs to the GcvT family.

338966:PPRO RS18020
gene id: 338966:PPRO_RS18020
uniprot id: A1AV44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

338966:PPRO RS19055
gene id: 338966:PPRO_RS19055
uniprot id: A0R855
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS17035
gene id: 338966:PPRO_RS17035
uniprot id: A1AUJ7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

338966:PPRO RS03860
gene id: 338966:PPRO_RS03860
uniprot id: A1AM49
names: Similarity
messages: Belongs to the UPF0751 family.

338966:PPRO RS08695
gene id: 338966:PPRO_RS08695
uniprot id: A1APT7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

338966:PPRO RS03655
gene id: 338966:PPRO_RS03655
uniprot id: A1AM06
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

338966:PPRO RS04095
gene id: 338966:PPRO_RS04095
uniprot id: A1AM95
names: Similarity
messages: Belongs to the UPF0166 family.

338966:PPRO RS05720
gene id: 338966:PPRO_RS05720
uniprot id: A1AN69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

338966:PPRO RS19545
gene id: 338966:PPRO_RS19545
uniprot id: A1AR59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

338966:PPRO RS15190
gene id: 338966:PPRO_RS15190
uniprot id: A1ATI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338966:PPRO RS03440
gene id: 338966:PPRO_RS03440
uniprot id: A1ALW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

338966:PPRO RS08150
gene id: 338966:PPRO_RS08150
uniprot id: A1API2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

338966:PPRO RS07825
gene id: 338966:PPRO_RS07825
uniprot id: A1APB6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

338966:PPRO RS05895
gene id: 338966:PPRO_RS05895
uniprot id: A1AN98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS08735
gene id: 338966:PPRO_RS08735
uniprot id: A1APU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS06330
gene id: 338966:PPRO_RS06330
uniprot id: A1ANI4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

338966:PPRO RS03145
gene id: 338966:PPRO_RS03145
uniprot id: A1ALQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS08515
gene id: 338966:PPRO_RS08515
uniprot id: A1APP9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

338966:PPRO RS00445
gene id: 338966:PPRO_RS00445
uniprot id: A1AK58
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS03240
gene id: 338966:PPRO_RS03240
uniprot id: A1ALS5
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

338966:PPRO RS19110
gene id: 338966:PPRO_RS19110
uniprot id: A0R850
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS03220
gene id: 338966:PPRO_RS03220
uniprot id: A1ALS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).
messages: Membrane

338966:PPRO RS03415
gene id: 338966:PPRO_RS03415
uniprot id: A1ALV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

338966:PPRO RS03700
gene id: 338966:PPRO_RS03700
uniprot id: A1AM15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

338966:PPRO RS17545
gene id: 338966:PPRO_RS17545
uniprot id: A1AUU8
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

338966:PPRO RS17775
gene id: 338966:PPRO_RS17775
uniprot id: A1AUZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

338966:PPRO RS18155
gene id: 338966:PPRO_RS18155
uniprot id: A0R7N0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338966:PPRO RS09125
gene id: 338966:PPRO_RS09125
uniprot id: A1AQ24
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338966:PPRO RS09845
gene id: 338966:PPRO_RS09845
uniprot id: A1AQH3
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12080
gene id: 338966:PPRO_RS12080
uniprot id: A1ARS6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

338966:PPRO RS01695
gene id: 338966:PPRO_RS01695
uniprot id: A1AKW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

338966:PPRO RS10500
gene id: 338966:PPRO_RS10500
uniprot id: A1AQV4
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

338966:PPRO RS03290
gene id: 338966:PPRO_RS03290
uniprot id: A1ALT0
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

338966:PPRO RS09850
gene id: 338966:PPRO_RS09850
uniprot id: A1AQH4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS10335
gene id: 338966:PPRO_RS10335
uniprot id: A1AQS1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

338966:PPRO RS10775
gene id: 338966:PPRO_RS10775
uniprot id: A1AR07
names: Similarity
messages: Belongs to the FemABX family.

338966:PPRO RS00565
gene id: 338966:PPRO_RS00565
uniprot id: A1AK82
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

338966:PPRO RS13980
gene id: 338966:PPRO_RS13980
uniprot id: A1ASU9
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338966:PPRO RS07475
gene id: 338966:PPRO_RS07475
uniprot id: A1ALL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338966:PPRO RS11895
gene id: 338966:PPRO_RS11895
uniprot id: A1ARP0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

338966:PPRO RS03500
gene id: 338966:PPRO_RS03500
uniprot id: A1ALX6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

338966:PPRO RS06160
gene id: 338966:PPRO_RS06160
uniprot id: A1ANF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338966:PPRO RS17030
gene id: 338966:PPRO_RS17030
uniprot id: A1AUJ6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

338966:PPRO RS05260
gene id: 338966:PPRO_RS05260
uniprot id: A1AMY0
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

338966:PPRO RS10040
gene id: 338966:PPRO_RS10040
uniprot id: A1AQL1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338966:PPRO RS04735
gene id: 338966:PPRO_RS04735
uniprot id: A1AMM7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

338966:PPRO RS13770
gene id: 338966:PPRO_RS13770
uniprot id: A1ASQ8
names: Similarity
messages: Belongs to the HupF/HypC family.

338966:PPRO RS18915
gene id: 338966:PPRO_RS18915
uniprot id: A0R7K2
names: Similarity
messages: Belongs to the ros/MucR family.

338966:PPRO RS02595
gene id: 338966:PPRO_RS02595
uniprot id: A1ALE0
names: Similarity
messages: Belongs to the DprA/Smf family.

338966:PPRO RS04730
gene id: 338966:PPRO_RS04730
uniprot id: A1AMM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

338966:PPRO RS07645
gene id: 338966:PPRO_RS07645
uniprot id: A1AP80
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17240
gene id: 338966:PPRO_RS17240
uniprot id: A1AUN7
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS03880
gene id: 338966:PPRO_RS03880
uniprot id: A1AM53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

338966:PPRO RS12615
gene id: 338966:PPRO_RS12615
uniprot id: A1AS38
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

338966:PPRO RS17300
gene id: 338966:PPRO_RS17300
uniprot id: A1AUP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS17000
gene id: 338966:PPRO_RS17000
uniprot id: A1AUJ0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338966:PPRO RS06825
gene id: 338966:PPRO_RS06825
uniprot id: A1ANR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

338966:PPRO RS02965
gene id: 338966:PPRO_RS02965
uniprot id: A1ALM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

338966:PPRO RS04705
gene id: 338966:PPRO_RS04705
uniprot id: A1AMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

338966:PPRO RS13840
gene id: 338966:PPRO_RS13840
uniprot id: A1ASR4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12980
gene id: 338966:PPRO_RS12980
uniprot id: A1ASB7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338966:PPRO RS05365
gene id: 338966:PPRO_RS05365
uniprot id: A1AN01
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

338966:PPRO RS06690
gene id: 338966:PPRO_RS06690
uniprot id: A1ANP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

338966:PPRO RS19475
gene id: 338966:PPRO_RS19475
uniprot id: A1AQ19
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

338966:PPRO RS04075
gene id: 338966:PPRO_RS04075
uniprot id: A1AM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338966:PPRO RS11115
gene id: 338966:PPRO_RS11115
uniprot id: A1AR77
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

338966:PPRO RS01975
gene id: 338966:PPRO_RS01975
uniprot id: A1AL20
names: Similarity
messages: Belongs to the glycosyl hydrolase 63 family.

338966:PPRO RS05710
gene id: 338966:PPRO_RS05710
uniprot id: A1AN67
names: Similarity
messages: Belongs to the LEA type 2 family.

338966:PPRO RS02715
gene id: 338966:PPRO_RS02715
uniprot id: A1ALG7
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338966:PPRO RS06155
gene id: 338966:PPRO_RS06155
uniprot id: A1ANE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338966:PPRO RS12600
gene id: 338966:PPRO_RS12600
uniprot id: A1AS35
names: Similarity
messages: Belongs to the peptidase S49 family.

338966:PPRO RS05035
gene id: 338966:PPRO_RS05035
uniprot id: A1AMT6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

338966:PPRO RS01250
gene id: 338966:PPRO_RS01250
uniprot id: A1AKM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm

338966:PPRO RS08725
gene id: 338966:PPRO_RS08725
uniprot id: A1APU3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

338966:PPRO RS03355
gene id: 338966:PPRO_RS03355
uniprot id: A1ALU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

338966:PPRO RS09260
gene id: 338966:PPRO_RS09260
uniprot id: A1AQ52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

338966:PPRO RS13760
gene id: 338966:PPRO_RS13760
uniprot id: A1ASQ6
names: Similarity
messages: Belongs to the HypE family.

338966:PPRO RS08950
gene id: 338966:PPRO_RS08950
uniprot id: A1APY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

338966:PPRO RS09300
gene id: 338966:PPRO_RS09300
uniprot id: A1AQ60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

338966:PPRO RS03400
gene id: 338966:PPRO_RS03400
uniprot id: A1ALV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

338966:PPRO RS10035
gene id: 338966:PPRO_RS10035
uniprot id: A1AQL0
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338966:PPRO RS04315
gene id: 338966:PPRO_RS04315
uniprot id: A1AMD9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

338966:PPRO RS00705
gene id: 338966:PPRO_RS00705
uniprot id: A1AKB1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS08955
gene id: 338966:PPRO_RS08955
uniprot id: A1APZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

338966:PPRO RS11135
gene id: 338966:PPRO_RS11135
uniprot id: A1AR81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

338966:PPRO RS02920
gene id: 338966:PPRO_RS02920
uniprot id: A1ALL2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

338966:PPRO RS09490
gene id: 338966:PPRO_RS09490
uniprot id: A0R849
names: Similarity
messages: Belongs to the transposase 7 family.

338966:PPRO RS11530
gene id: 338966:PPRO_RS11530
uniprot id: A1ARG4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

338966:PPRO RS17945
gene id: 338966:PPRO_RS17945
uniprot id: A1AV29
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

338966:PPRO RS04165
gene id: 338966:PPRO_RS04165
uniprot id: A1AMA9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

338966:PPRO RS14630
gene id: 338966:PPRO_RS14630
uniprot id: A1AT75
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS12455
gene id: 338966:PPRO_RS12455
uniprot id: A1AS05
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

338966:PPRO RS07665
gene id: 338966:PPRO_RS07665
uniprot id: A1AP84
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08520
gene id: 338966:PPRO_RS08520
uniprot id: A1APQ0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

338966:PPRO RS11655
gene id: 338966:PPRO_RS11655
uniprot id: A1ARI9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338966:PPRO RS03130
gene id: 338966:PPRO_RS03130
uniprot id: A1ALQ3
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

338966:PPRO RS06020
gene id: 338966:PPRO_RS06020
uniprot id: A1ANC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Part of an ABC transporter complex. Responsible for energy coupling to the transport system.

338966:PPRO RS03405
gene id: 338966:PPRO_RS03405
uniprot id: A1ALV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

338966:PPRO RS07950
gene id: 338966:PPRO_RS07950
uniprot id: A1APE1
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

338966:PPRO RS00005
gene id: 338966:PPRO_RS00005
uniprot id: A1AJX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

338966:PPRO RS16855
gene id: 338966:PPRO_RS16855
uniprot id: A1AUF7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

338966:PPRO RS03185
gene id: 338966:PPRO_RS03185
uniprot id: A1ALR4
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

338966:PPRO RS13595
gene id: 338966:PPRO_RS13595
uniprot id: A1ASM3
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS09980
gene id: 338966:PPRO_RS09980
uniprot id: A1AQJ9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

338966:PPRO RS16570
gene id: 338966:PPRO_RS16570
uniprot id: A1AU99
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

338966:PPRO RS02440
gene id: 338966:PPRO_RS02440
uniprot id: A1ALB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

338966:PPRO RS06395
gene id: 338966:PPRO_RS06395
uniprot id: A1ANJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

338966:PPRO RS19020
gene id: 338966:PPRO_RS19020
uniprot id: A0R848
names: Similarity
messages: Belongs to the MobA/MobL family.

338966:PPRO RS06200
gene id: 338966:PPRO_RS06200
uniprot id: A1ANF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

338966:PPRO RS17490
gene id: 338966:PPRO_RS17490
uniprot id: A1AUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

338966:PPRO RS04330
gene id: 338966:PPRO_RS04330
uniprot id: A1AME2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS01875
gene id: 338966:PPRO_RS01875
uniprot id: A1AKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

338966:PPRO RS08135
gene id: 338966:PPRO_RS08135
uniprot id: A1ALQ0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14050
gene id: 338966:PPRO_RS14050
uniprot id: A1ASW3
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

338966:PPRO RS07590
gene id: 338966:PPRO_RS07590
uniprot id: A1AP71
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

338966:PPRO RS04775
gene id: 338966:PPRO_RS04775
uniprot id: A1AMN5
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

338966:PPRO RS01465
gene id: 338966:PPRO_RS01465
uniprot id: A1AKR8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

338966:PPRO RS12835
gene id: 338966:PPRO_RS12835
uniprot id: A1AS85
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

338966:PPRO RS15765
gene id: 338966:PPRO_RS15765
uniprot id: A1ATU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

338966:PPRO RS06695
gene id: 338966:PPRO_RS06695
uniprot id: A1ANP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

338966:PPRO RS09120
gene id: 338966:PPRO_RS09120
uniprot id: A1AQ23
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338966:PPRO RS10750
gene id: 338966:PPRO_RS10750
uniprot id: A1AR02
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

338966:PPRO RS04570
gene id: 338966:PPRO_RS04570
uniprot id: A1AMJ0
names: Similarity
messages: Belongs to the group II decarboxylase family.

338966:PPRO RS13910
gene id: 338966:PPRO_RS13910
uniprot id: A1AST6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

338966:PPRO RS06220
gene id: 338966:PPRO_RS06220
uniprot id: A1ANG2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

338966:PPRO RS12580
gene id: 338966:PPRO_RS12580
uniprot id: A1AS31
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

338966:PPRO RS08410
gene id: 338966:PPRO_RS08410
uniprot id: A1APN0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

338966:PPRO RS13765
gene id: 338966:PPRO_RS13765
uniprot id: A1ASQ7
names: Similarity
messages: Belongs to the HypD family.

338966:PPRO RS15655
gene id: 338966:PPRO_RS15655
uniprot id: A1ATS0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS00515
gene id: 338966:PPRO_RS00515
uniprot id: A1AK73
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

338966:PPRO RS15250
gene id: 338966:PPRO_RS15250
uniprot id: A1ATJ3
names: Similarity
messages: Belongs to the hemerythrin family.

338966:PPRO RS03125
gene id: 338966:PPRO_RS03125
uniprot id: A1ALQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS08545
gene id: 338966:PPRO_RS08545
uniprot id: A1APQ6
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338966:PPRO RS07015
gene id: 338966:PPRO_RS07015
uniprot id: A1ANV7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

338966:PPRO RS08140
gene id: 338966:PPRO_RS08140
uniprot id: A1API0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

338966:PPRO RS15030
gene id: 338966:PPRO_RS15030
uniprot id: A1ATF5
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

338966:PPRO RS06415
gene id: 338966:PPRO_RS06415
uniprot id: A1ANJ5
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

338966:PPRO RS11020
gene id: 338966:PPRO_RS11020
uniprot id: A1AR57
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS09500
gene id: 338966:PPRO_RS09500
uniprot id: A0R851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338966:PPRO RS02515
gene id: 338966:PPRO_RS02515
uniprot id: A1ALC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

338966:PPRO RS14295
gene id: 338966:PPRO_RS14295
uniprot id: A1AT10
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

338966:PPRO RS17060
gene id: 338966:PPRO_RS17060
uniprot id: A1AUK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS03390
gene id: 338966:PPRO_RS03390
uniprot id: A1ALV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

338966:PPRO RS05765
gene id: 338966:PPRO_RS05765
uniprot id: A1AN79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS15840
gene id: 338966:PPRO_RS15840
uniprot id: A1ALP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS16385
gene id: 338966:PPRO_RS16385
uniprot id: A1AU62
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15780
gene id: 338966:PPRO_RS15780
uniprot id: A1ATU4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

338966:PPRO RS08100
gene id: 338966:PPRO_RS08100
uniprot id: A1ALP3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338966:PPRO RS07490
gene id: 338966:PPRO_RS07490
uniprot id: A1AP51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338966:PPRO RS08825
gene id: 338966:PPRO_RS08825
uniprot id: A1APW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

338966:PPRO RS16980
gene id: 338966:PPRO_RS16980
uniprot id: A1AUI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS05805
gene id: 338966:PPRO_RS05805
uniprot id: A1AN85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

338966:PPRO RS09755
gene id: 338966:PPRO_RS09755
uniprot id: A1AQF5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS03075
gene id: 338966:PPRO_RS03075
uniprot id: A1ALP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS19035
gene id: 338966:PPRO_RS19035
uniprot id: A0R851
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338966:PPRO RS17375
gene id: 338966:PPRO_RS17375
uniprot id: A1AUR3
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

338966:PPRO RS08355
gene id: 338966:PPRO_RS08355
uniprot id: A1APM4
names: Similarity
messages: Belongs to the P(II) protein family.

338966:PPRO RS02915
gene id: 338966:PPRO_RS02915
uniprot id: A1ALL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

338966:PPRO RS15285
gene id: 338966:PPRO_RS15285
uniprot id: A1ATK1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338966:PPRO RS02350
gene id: 338966:PPRO_RS02350
uniprot id: A1AL92
names: Similarity
messages: Belongs to the UDPGP type 2 family.

338966:PPRO RS05165
gene id: 338966:PPRO_RS05165
uniprot id: A1AMW2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

338966:PPRO RS09900
gene id: 338966:PPRO_RS09900
uniprot id: A1AQI3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

338966:PPRO RS17895
gene id: 338966:PPRO_RS17895
uniprot id: A1AV18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

338966:PPRO RS08225
gene id: 338966:PPRO_RS08225
uniprot id: A1APJ6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS05320
gene id: 338966:PPRO_RS05320
uniprot id: A1AMZ2
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS00350
gene id: 338966:PPRO_RS00350
uniprot id: A1AK41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

338966:PPRO RS03340
gene id: 338966:PPRO_RS03340
uniprot id: A1ALU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

338966:PPRO RS06095
gene id: 338966:PPRO_RS06095
uniprot id: A1AND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS08890
gene id: 338966:PPRO_RS08890
uniprot id: A1APX7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS10030
gene id: 338966:PPRO_RS10030
uniprot id: A1AQK9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

338966:PPRO RS12115
gene id: 338966:PPRO_RS12115
uniprot id: A1ART3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

338966:PPRO RS02940
gene id: 338966:PPRO_RS02940
uniprot id: A1ALL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338966:PPRO RS14640
gene id: 338966:PPRO_RS14640
uniprot id: A1AT77
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.

338966:PPRO RS12480
gene id: 338966:PPRO_RS12480
uniprot id: A1AS10
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338966:PPRO RS18100
gene id: 338966:PPRO_RS18100
uniprot id: A0R7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338966:PPRO RS03595
gene id: 338966:PPRO_RS03595
uniprot id: A1ALZ5
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

338966:PPRO RS12515
gene id: 338966:PPRO_RS12515
uniprot id: A1AS17
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

338966:PPRO RS08805
gene id: 338966:PPRO_RS08805
uniprot id: A1APW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

338966:PPRO RS16815
gene id: 338966:PPRO_RS16815
uniprot id: A1AUE9
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

338966:PPRO RS01015
gene id: 338966:PPRO_RS01015
uniprot id: A1AKH3
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

338966:PPRO RS08405
gene id: 338966:PPRO_RS08405
uniprot id: A1APM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS08025
gene id: 338966:PPRO_RS08025
uniprot id: A1APF6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

338966:PPRO RS12335
gene id: 338966:PPRO_RS12335
uniprot id: A1ARY0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

338966:PPRO RS00135
gene id: 338966:PPRO_RS00135
uniprot id: A1AJZ7
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

338966:PPRO RS16115
gene id: 338966:PPRO_RS16115
uniprot id: A1AU09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-ACP thioesterase family.
messages: chloroplast

338966:PPRO RS13885
gene id: 338966:PPRO_RS13885
uniprot id: A1AST1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

338966:PPRO RS19030
gene id: 338966:PPRO_RS19030
uniprot id: A0R850
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS05615
gene id: 338966:PPRO_RS05615
uniprot id: A1AN49
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

338966:PPRO RS03420
gene id: 338966:PPRO_RS03420
uniprot id: A1ALV8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

338966:PPRO RS03450
gene id: 338966:PPRO_RS03450
uniprot id: A1ALW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

338966:PPRO RS12210
gene id: 338966:PPRO_RS12210
uniprot id: A1ARV4
names: Similarity
messages: Belongs to the FemABX family.

338966:PPRO RS06635
gene id: 338966:PPRO_RS06635
uniprot id: A1ANN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338966:PPRO RS08925
gene id: 338966:PPRO_RS08925
uniprot id: A1APY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

338966:PPRO RS06390
gene id: 338966:PPRO_RS06390
uniprot id: A1ANJ0
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

338966:PPRO RS05325
gene id: 338966:PPRO_RS05325
uniprot id: A1AMZ3
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

338966:PPRO RS11705
gene id: 338966:PPRO_RS11705
uniprot id: A1ARJ9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

338966:PPRO RS09960
gene id: 338966:PPRO_RS09960
uniprot id: A1AQJ5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

338966:PPRO RS13560
gene id: 338966:PPRO_RS13560
uniprot id: A1ASL7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

338966:PPRO RS05565
gene id: 338966:PPRO_RS05565
uniprot id: A1AN38
names: Similarity
messages: Belongs to the citrate synthase family.

338966:PPRO RS07170
gene id: 338966:PPRO_RS07170
uniprot id: A1ANY6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338966:PPRO RS10710
gene id: 338966:PPRO_RS10710
uniprot id: A1AQZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS11555
gene id: 338966:PPRO_RS11555
uniprot id: A1ARG9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15305
gene id: 338966:PPRO_RS15305
uniprot id: A1ATK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

338966:PPRO RS04740
gene id: 338966:PPRO_RS04740
uniprot id: A1AMM8
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

338966:PPRO RS12610
gene id: 338966:PPRO_RS12610
uniprot id: A1AS37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

338966:PPRO RS18490
gene id: 338966:PPRO_RS18490
uniprot id: A0R7W8
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS17835
gene id: 338966:PPRO_RS17835
uniprot id: A1AV06
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS01970
gene id: 338966:PPRO_RS01970
uniprot id: A1AL19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

338966:PPRO RS04790
gene id: 338966:PPRO_RS04790
uniprot id: A1AMN8
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS01820
gene id: 338966:PPRO_RS01820
uniprot id: A1AKY7
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

338966:PPRO RS15005
gene id: 338966:PPRO_RS15005
uniprot id: A1ATF0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338966:PPRO RS12470
gene id: 338966:PPRO_RS12470
uniprot id: A1AS08
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS08780
gene id: 338966:PPRO_RS08780
uniprot id: A1APV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

338966:PPRO RS13900
gene id: 338966:PPRO_RS13900
uniprot id: A1AST4
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

338966:PPRO RS02630
gene id: 338966:PPRO_RS02630
uniprot id: A1ALE7
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS16325
gene id: 338966:PPRO_RS16325
uniprot id: A1AU50
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS10190
gene id: 338966:PPRO_RS10190
uniprot id: A1AQP2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

338966:PPRO RS05695
gene id: 338966:PPRO_RS05695
uniprot id: A1AN64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

338966:PPRO RS14980
gene id: 338966:PPRO_RS14980
uniprot id: A1ATE5
names: Similarity
messages: Belongs to the Skp family.

338966:PPRO RS05655
gene id: 338966:PPRO_RS05655
uniprot id: A1AN56
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

338966:PPRO RS09595
gene id: 338966:PPRO_RS09595
uniprot id: A1AQC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

338966:PPRO RS06670
gene id: 338966:PPRO_RS06670
uniprot id: A1ANP4
names: Similarity
messages: Belongs to the UPF0047 family.

338966:PPRO RS00075
gene id: 338966:PPRO_RS00075
uniprot id: A1AJY7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

338966:PPRO RS05915
gene id: 338966:PPRO_RS05915
uniprot id: A1ANA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

338966:PPRO RS15965
gene id: 338966:PPRO_RS15965
uniprot id: A1ATY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

338966:PPRO RS09625
gene id: 338966:PPRO_RS09625
uniprot id: A1AQC9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS05820
gene id: 338966:PPRO_RS05820
uniprot id: A1AN87
names: Similarity
messages: Belongs to the SUI1 family.

338966:PPRO RS04355
gene id: 338966:PPRO_RS04355
uniprot id: A1AME7
names: Similarity
messages: Belongs to the AOR/FOR family.

338966:PPRO RS06030
gene id: 338966:PPRO_RS06030
uniprot id: A1ANC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

338966:PPRO RS02855
gene id: 338966:PPRO_RS02855
uniprot id: A1ALJ9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14905
gene id: 338966:PPRO_RS14905
uniprot id: A1ATD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

338966:PPRO RS09015
gene id: 338966:PPRO_RS09015
uniprot id: A1AQ02
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338966:PPRO RS04690
gene id: 338966:PPRO_RS04690
uniprot id: A1AML8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

338966:PPRO RS08360
gene id: 338966:PPRO_RS08360
uniprot id: A1APM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

338966:PPRO RS05800
gene id: 338966:PPRO_RS05800
uniprot id: A1AN84
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

338966:PPRO RS17495
gene id: 338966:PPRO_RS17495
uniprot id: A1AUT8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338966:PPRO RS14560
gene id: 338966:PPRO_RS14560
uniprot id: A1AT63
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

338966:PPRO RS08940
gene id: 338966:PPRO_RS08940
uniprot id: A1APY7
names: Similarity
messages: Belongs to the RecJ family.

338966:PPRO RS05580
gene id: 338966:PPRO_RS05580
uniprot id: A1AN41
names: Similarity
messages: Belongs to the thioesterase PaaI family.

338966:PPRO RS11730
gene id: 338966:PPRO_RS11730
uniprot id: A1ARK4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS15105
gene id: 338966:PPRO_RS15105
uniprot id: A1ATH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS15165
gene id: 338966:PPRO_RS15165
uniprot id: A1ATH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

338966:PPRO RS14665
gene id: 338966:PPRO_RS14665
uniprot id: A1AT82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

338966:PPRO RS02020
gene id: 338966:PPRO_RS02020
uniprot id: A1AL29
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

338966:PPRO RS17960
gene id: 338966:PPRO_RS17960
uniprot id: A1AV32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

338966:PPRO RS03300
gene id: 338966:PPRO_RS03300
uniprot id: A1ALT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

338966:PPRO RS12265
gene id: 338966:PPRO_RS12265
uniprot id: A1ARW6
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

338966:PPRO RS10960
gene id: 338966:PPRO_RS10960
uniprot id: A1AR45
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS04065
gene id: 338966:PPRO_RS04065
uniprot id: A1AM89
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15715
gene id: 338966:PPRO_RS15715
uniprot id: A1ATT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338966:PPRO RS00615
gene id: 338966:PPRO_RS00615
uniprot id: A1AK93
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

338966:PPRO RS01430
gene id: 338966:PPRO_RS01430
uniprot id: A1AKR2
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

338966:PPRO RS00710
gene id: 338966:PPRO_RS00710
uniprot id: A1AKB2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17515
gene id: 338966:PPRO_RS17515
uniprot id: A1AUU2
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

338966:PPRO RS03790
gene id: 338966:PPRO_RS03790
uniprot id: A1AM36
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

338966:PPRO RS14020
gene id: 338966:PPRO_RS14020
uniprot id: A1ASV7
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

338966:PPRO RS13050
gene id: 338966:PPRO_RS13050
uniprot id: A1ASD1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

338966:PPRO RS14280
gene id: 338966:PPRO_RS14280
uniprot id: A1AT07
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS18010
gene id: 338966:PPRO_RS18010
uniprot id: A1AV42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

338966:PPRO RS04450
gene id: 338966:PPRO_RS04450
uniprot id: A1AMG6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338966:PPRO RS13010
gene id: 338966:PPRO_RS13010
uniprot id: A1ASC3
names: Similarity
messages: Belongs to the peptidase C40 family.

338966:PPRO RS08900
gene id: 338966:PPRO_RS08900
uniprot id: A1APX9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338966:PPRO RS10150
gene id: 338966:PPRO_RS10150
uniprot id: A1AQN4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

338966:PPRO RS17045
gene id: 338966:PPRO_RS17045
uniprot id: A1AUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

338966:PPRO RS06665
gene id: 338966:PPRO_RS06665
uniprot id: A1ANP3
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

338966:PPRO RS16755
gene id: 338966:PPRO_RS16755
uniprot id: A1AUD7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08705
gene id: 338966:PPRO_RS08705
uniprot id: A1APT9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

338966:PPRO RS09215
gene id: 338966:PPRO_RS09215
uniprot id: A1AQ44
names: Similarity
messages: Belongs to the pyruvate kinase family.

338966:PPRO RS17890
gene id: 338966:PPRO_RS17890
uniprot id: A1AV17
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

338966:PPRO RS00055
gene id: 338966:PPRO_RS00055
uniprot id: A1AJY3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

338966:PPRO RS10165
gene id: 338966:PPRO_RS10165
uniprot id: A1AQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

338966:PPRO RS16790
gene id: 338966:PPRO_RS16790
uniprot id: A1AUE4
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

338966:PPRO RS08865
gene id: 338966:PPRO_RS08865
uniprot id: A1APX2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338966:PPRO RS03545
gene id: 338966:PPRO_RS03545
uniprot id: A1ALY5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS15900
gene id: 338966:PPRO_RS15900
uniprot id: A1ATW8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS13785
gene id: 338966:PPRO_RS13785
uniprot id: A1ASR1
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

338966:PPRO RS04270
gene id: 338966:PPRO_RS04270
uniprot id: A1AMD0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

338966:PPRO RS08450
gene id: 338966:PPRO_RS08450
uniprot id: A1APN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

338966:PPRO RS17075
gene id: 338966:PPRO_RS17075
uniprot id: A1AUK5
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

338966:PPRO RS07510
gene id: 338966:PPRO_RS07510
uniprot id: A1AP55
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS04710
gene id: 338966:PPRO_RS04710
uniprot id: A1AMM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

338966:PPRO RS14575
gene id: 338966:PPRO_RS14575
uniprot id: A1AT66
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

338966:PPRO RS17580
gene id: 338966:PPRO_RS17580
uniprot id: A1AUV5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

338966:PPRO RS10010
gene id: 338966:PPRO_RS10010
uniprot id: A1AQK5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338966:PPRO RS11175
gene id: 338966:PPRO_RS11175
uniprot id: A1AR89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

338966:PPRO RS08435
gene id: 338966:PPRO_RS08435
uniprot id: A1APN5
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

338966:PPRO RS08710
gene id: 338966:PPRO_RS08710
uniprot id: A1APU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS00295
gene id: 338966:PPRO_RS00295
uniprot id: A1AK30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS10140
gene id: 338966:PPRO_RS10140
uniprot id: A1AQN2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

338966:PPRO RS13440
gene id: 338966:PPRO_RS13440
uniprot id: A1ASJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

338966:PPRO RS06990
gene id: 338966:PPRO_RS06990
uniprot id: A1ANV2
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

338966:PPRO RS19275
gene id: 338966:PPRO_RS19275
uniprot id: A1ALP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS03430
gene id: 338966:PPRO_RS03430
uniprot id: A1ALW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

338966:PPRO RS07235
gene id: 338966:PPRO_RS07235
uniprot id: A1AP00
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338966:PPRO RS13525
gene id: 338966:PPRO_RS13525
uniprot id: A1ASL0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

338966:PPRO RS08230
gene id: 338966:PPRO_RS08230
uniprot id: A1APJ8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

338966:PPRO RS17270
gene id: 338966:PPRO_RS17270
uniprot id: A1AUP2
names: Similarity
messages: Belongs to the MotB family.

338966:PPRO RS10875
gene id: 338966:PPRO_RS10875
uniprot id: A1AR28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

338966:PPRO RS12630
gene id: 338966:PPRO_RS12630
uniprot id: A1AS41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

338966:PPRO RS12595
gene id: 338966:PPRO_RS12595
uniprot id: A1AS34
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

338966:PPRO RS15875
gene id: 338966:PPRO_RS15875
uniprot id: A1ALP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS01600
gene id: 338966:PPRO_RS01600
uniprot id: A1AKU5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS19025
gene id: 338966:PPRO_RS19025
uniprot id: A0R849
names: Similarity
messages: Belongs to the transposase 7 family.

338966:PPRO RS02005
gene id: 338966:PPRO_RS02005
uniprot id: A1AL26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338966:PPRO RS11920
gene id: 338966:PPRO_RS11920
uniprot id: A1ARP5
names: Similarity
messages: Belongs to the peptidase S41A family.

338966:PPRO RS03685
gene id: 338966:PPRO_RS03685
uniprot id: A1AM12
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS10005
gene id: 338966:PPRO_RS10005
uniprot id: A1AQK4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

338966:PPRO RS01665
gene id: 338966:PPRO_RS01665
uniprot id: A1AKV7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338966:PPRO RS10640
gene id: 338966:PPRO_RS10640
uniprot id: A1AQY1
names: Similarity
messages: Belongs to the archease family.

338966:PPRO RS06985
gene id: 338966:PPRO_RS06985
uniprot id: A1ANV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

338966:PPRO RS12415
gene id: 338966:PPRO_RS12415
uniprot id: A1ARZ7
names: Similarity
messages: Belongs to the GSP E family.

338966:PPRO RS05040
gene id: 338966:PPRO_RS05040
uniprot id: A1AMT7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

338966:PPRO RS17870
gene id: 338966:PPRO_RS17870
uniprot id: A1AV13
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

338966:PPRO RS12465
gene id: 338966:PPRO_RS12465
uniprot id: A1AS07
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

338966:PPRO RS11410
gene id: 338966:PPRO_RS11410
uniprot id: A1ARE1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338966:PPRO RS08700
gene id: 338966:PPRO_RS08700
uniprot id: A1APT8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

338966:PPRO RS11865
gene id: 338966:PPRO_RS11865
uniprot id: A1ARN4
names: Similarity
messages: Belongs to the RutC family.

338966:PPRO RS13020
gene id: 338966:PPRO_RS13020
uniprot id: A1ASC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

338966:PPRO RS17880
gene id: 338966:PPRO_RS17880
uniprot id: A1AV15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

338966:PPRO RS08160
gene id: 338966:PPRO_RS08160
uniprot id: A1API4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17530
gene id: 338966:PPRO_RS17530
uniprot id: A1AUU5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08475
gene id: 338966:PPRO_RS08475
uniprot id: A1APP2
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

338966:PPRO RS02975
gene id: 338966:PPRO_RS02975
uniprot id: A1ALM3
names: Similarity
messages: Belongs to the UPF0237 family.

338966:PPRO RS11550
gene id: 338966:PPRO_RS11550
uniprot id: A1ARG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

338966:PPRO RS14395
gene id: 338966:PPRO_RS14395
uniprot id: A1AT30
names: Similarity
messages: Belongs to the UPF0502 family.

338966:PPRO RS02215
gene id: 338966:PPRO_RS02215
uniprot id: A1AL65
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

338966:PPRO RS10950
gene id: 338966:PPRO_RS10950
uniprot id: A1AR43
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS03725
gene id: 338966:PPRO_RS03725
uniprot id: A1AM21
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

338966:PPRO RS03425
gene id: 338966:PPRO_RS03425
uniprot id: A1ALW0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

338966:PPRO RS15095
gene id: 338966:PPRO_RS15095
uniprot id: A1ATG9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

338966:PPRO RS13195
gene id: 338966:PPRO_RS13195
uniprot id: A1ASF2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

338966:PPRO RS07420
gene id: 338966:PPRO_RS07420
uniprot id: A1AP35
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338966:PPRO RS13810
gene id: 338966:PPRO_RS13810
uniprot id: A1ASR6
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS12675
gene id: 338966:PPRO_RS12675
uniprot id: A1AS51
names: Similarity
messages: Belongs to the UPF0270 family.

338966:PPRO RS02880
gene id: 338966:PPRO_RS02880
uniprot id: A1ALK4
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

338966:PPRO RS11200
gene id: 338966:PPRO_RS11200
uniprot id: A1AR94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

338966:PPRO RS02085
gene id: 338966:PPRO_RS02085
uniprot id: A1AL40
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

338966:PPRO RS09115
gene id: 338966:PPRO_RS09115
uniprot id: A1AQ22
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338966:PPRO RS04455
gene id: 338966:PPRO_RS04455
uniprot id: A1AMG7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

338966:PPRO RS17190
gene id: 338966:PPRO_RS17190
uniprot id: A1AUM8
names: Similarity
messages: Belongs to the bacterial flagellin family.

338966:PPRO RS02615
gene id: 338966:PPRO_RS02615
uniprot id: A1ALE4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15350
gene id: 338966:PPRO_RS15350
uniprot id: A1ATL4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

338966:PPRO RS16110
gene id: 338966:PPRO_RS16110
uniprot id: A1AU08
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS11670
gene id: 338966:PPRO_RS11670
uniprot id: A1ARJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

338966:PPRO RS06430
gene id: 338966:PPRO_RS06430
uniprot id: A1ANJ8
names: Similarity
messages: Belongs to the CobH/CbiC family.

338966:PPRO RS08610
gene id: 338966:PPRO_RS08610
uniprot id: A1APR9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

338966:PPRO RS01580
gene id: 338966:PPRO_RS01580
uniprot id: A1AKU1
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17560
gene id: 338966:PPRO_RS17560
uniprot id: A1AUV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS09990
gene id: 338966:PPRO_RS09990
uniprot id: A1AQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS11015
gene id: 338966:PPRO_RS11015
uniprot id: A1AR56
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS02540
gene id: 338966:PPRO_RS02540
uniprot id: A1ALC9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

338966:PPRO RS13380
gene id: 338966:PPRO_RS13380
uniprot id: A1ASI5
names: Similarity
messages: Belongs to the bacterial secretin family.

338966:PPRO RS16565
gene id: 338966:PPRO_RS16565
uniprot id: A1AU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338966:PPRO RS05360
gene id: 338966:PPRO_RS05360
uniprot id: A1AN00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

338966:PPRO RS12780
gene id: 338966:PPRO_RS12780
uniprot id: A1AS73
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

338966:PPRO RS08690
gene id: 338966:PPRO_RS08690
uniprot id: A1APT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

338966:PPRO RS14705
gene id: 338966:PPRO_RS14705
uniprot id: A1AT90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

338966:PPRO RS01595
gene id: 338966:PPRO_RS01595
uniprot id: A1AKU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS13850
gene id: 338966:PPRO_RS13850
uniprot id: A1ASR6
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS18445
gene id: 338966:PPRO_RS18445
uniprot id: A0R7X4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS05745
gene id: 338966:PPRO_RS05745
uniprot id: A1AN74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

338966:PPRO RS08675
gene id: 338966:PPRO_RS08675
uniprot id: A1APT2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

338966:PPRO RS13590
gene id: 338966:PPRO_RS13590
uniprot id: A1ASM2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS09295
gene id: 338966:PPRO_RS09295
uniprot id: A1AQ59
names: Similarity
messages: Belongs to the XseB family.

338966:PPRO RS00385
gene id: 338966:PPRO_RS00385
uniprot id: A1AK46
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS04680
gene id: 338966:PPRO_RS04680
uniprot id: A1AML6
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338966:PPRO RS11900
gene id: 338966:PPRO_RS11900
uniprot id: A1ARP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

338966:PPRO RS15290
gene id: 338966:PPRO_RS15290
uniprot id: A1ATK2
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

338966:PPRO RS06245
gene id: 338966:PPRO_RS06245
uniprot id: A1ANG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS02325
gene id: 338966:PPRO_RS02325
uniprot id: A1AL88
names: Similarity
messages: Belongs to the Skp family.

338966:PPRO RS03825
gene id: 338966:PPRO_RS03825
uniprot id: A1AM42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338966:PPRO RS17340
gene id: 338966:PPRO_RS17340
uniprot id: A1AUQ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS01640
gene id: 338966:PPRO_RS01640
uniprot id: A1AKV2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08105
gene id: 338966:PPRO_RS08105
uniprot id: A1ALP4
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338966:PPRO RS15370
gene id: 338966:PPRO_RS15370
uniprot id: A1ATL8
names: Similarity
messages: Belongs to the UPF0234 family.

338966:PPRO RS10465
gene id: 338966:PPRO_RS10465
uniprot id: A1AQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS08300
gene id: 338966:PPRO_RS08300
uniprot id: A1APL3
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

338966:PPRO RS10260
gene id: 338966:PPRO_RS10260
uniprot id: A1AQQ6
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS11400
gene id: 338966:PPRO_RS11400
uniprot id: A1ARD9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS18015
gene id: 338966:PPRO_RS18015
uniprot id: A1AV43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

338966:PPRO RS05690
gene id: 338966:PPRO_RS05690
uniprot id: A1AN63
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

338966:PPRO RS19485
gene id: 338966:PPRO_RS19485
uniprot id: A1AQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

338966:PPRO RS10870
gene id: 338966:PPRO_RS10870
uniprot id: A1AR27
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338966:PPRO RS15070
gene id: 338966:PPRO_RS15070
uniprot id: A1ATG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

338966:PPRO RS08155
gene id: 338966:PPRO_RS08155
uniprot id: A1API3
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS12370
gene id: 338966:PPRO_RS12370
uniprot id: A1ARY8
names: Similarity
messages: Belongs to the ArsC family.

338966:PPRO RS11695
gene id: 338966:PPRO_RS11695
uniprot id: A1ARJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

338966:PPRO RS18530
gene id: 338966:PPRO_RS18530
uniprot id: A0R7W3
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

338966:PPRO RS15730
gene id: 338966:PPRO_RS15730
uniprot id: A1ATT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

338966:PPRO RS13360
gene id: 338966:PPRO_RS13360
uniprot id: A1ASI1
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15735
gene id: 338966:PPRO_RS15735
uniprot id: A1ATT5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

338966:PPRO RS13175
gene id: 338966:PPRO_RS13175
uniprot id: A1ASE8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS00020
gene id: 338966:PPRO_RS00020
uniprot id: A1AJX5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

338966:PPRO RS00300
gene id: 338966:PPRO_RS00300
uniprot id: A1AK31
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS16800
gene id: 338966:PPRO_RS16800
uniprot id: A1AUE6
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338966:PPRO RS15850
gene id: 338966:PPRO_RS15850
uniprot id: A1ALP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS16445
gene id: 338966:PPRO_RS16445
uniprot id: A1AU74
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

338966:PPRO RS17295
gene id: 338966:PPRO_RS17295
uniprot id: A1AUP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

338966:PPRO RS14760
gene id: 338966:PPRO_RS14760
uniprot id: A1ATA1
names: Function
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.

338966:PPRO RS07320
gene id: 338966:PPRO_RS07320
uniprot id: A1AP16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS12795
gene id: 338966:PPRO_RS12795
uniprot id: A1AS76
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

338966:PPRO RS14300
gene id: 338966:PPRO_RS14300
uniprot id: A1AT11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

338966:PPRO RS21565
gene id: 338966:PPRO_RS21565
uniprot id: A1AUQ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

338966:PPRO RS10160
gene id: 338966:PPRO_RS10160
uniprot id: A1AQN6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

338966:PPRO RS07850
gene id: 338966:PPRO_RS07850
uniprot id: A1APC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

338966:PPRO RS06060
gene id: 338966:PPRO_RS06060
uniprot id: A1AND2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS01620
gene id: 338966:PPRO_RS01620
uniprot id: A1AKU8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

338966:PPRO RS10900
gene id: 338966:PPRO_RS10900
uniprot id: A1AR32
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

338966:PPRO RS06840
gene id: 338966:PPRO_RS06840
uniprot id: A1ANS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

338966:PPRO RS16810
gene id: 338966:PPRO_RS16810
uniprot id: A1AUE8
names: Similarity
messages: Belongs to the SfsA family.

338966:PPRO RS11630
gene id: 338966:PPRO_RS11630
uniprot id: A1ARI4
names: Similarity
messages: Belongs to the peptidase S16 family.

338966:PPRO RS05755
gene id: 338966:PPRO_RS05755
uniprot id: A1AN77
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

338966:PPRO RS15790
gene id: 338966:PPRO_RS15790
uniprot id: A1ATU6
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

338966:PPRO RS15010
gene id: 338966:PPRO_RS15010
uniprot id: A1ATF1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

338966:PPRO RS17040
gene id: 338966:PPRO_RS17040
uniprot id: A1AUJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

338966:PPRO RS04155
gene id: 338966:PPRO_RS04155
uniprot id: A1AMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

338966:PPRO RS08970
gene id: 338966:PPRO_RS08970
uniprot id: A1APZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

338966:PPRO RS03445
gene id: 338966:PPRO_RS03445
uniprot id: A1ALW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

338966:PPRO RS12860
gene id: 338966:PPRO_RS12860
uniprot id: A1AS90
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

338966:PPRO RS05700
gene id: 338966:PPRO_RS05700
uniprot id: A1AN65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

338966:PPRO RS17350
gene id: 338966:PPRO_RS17350
uniprot id: A1AUQ8
names: Similarity
messages: Belongs to the Nth/MutY family.

338966:PPRO RS17460
gene id: 338966:PPRO_RS17460
uniprot id: A1AUT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

338966:PPRO RS12585
gene id: 338966:PPRO_RS12585
uniprot id: A1AS32
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

338966:PPRO RS03060
gene id: 338966:PPRO_RS03060
uniprot id: A1ALN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

338966:PPRO RS01345
gene id: 338966:PPRO_RS01345
uniprot id: A1AKP5
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

338966:PPRO RS06845
gene id: 338966:PPRO_RS06845
uniprot id: A1ANS2
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

338966:PPRO RS00310
gene id: 338966:PPRO_RS00310
uniprot id: A1AK33
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

338966:PPRO RS10495
gene id: 338966:PPRO_RS10495
uniprot id: A1AQV3
names: Similarity
messages: Belongs to the peptidase M29 family.

338966:PPRO RS08430
gene id: 338966:PPRO_RS08430
uniprot id: A1APN4
names: Similarity
messages: Belongs to the MEMO1 family.

338966:PPRO RS04200
gene id: 338966:PPRO_RS04200
uniprot id: A1AMB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS00600
gene id: 338966:PPRO_RS00600
uniprot id: A1AK90
names: Similarity
messages: Belongs to the glutathione peroxidase family.

338966:PPRO RS14655
gene id: 338966:PPRO_RS14655
uniprot id: A1AT80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

338966:PPRO RS02105
gene id: 338966:PPRO_RS02105
uniprot id: A1AL44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

338966:PPRO RS15085
gene id: 338966:PPRO_RS15085
uniprot id: A1ATG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

338966:PPRO RS11415
gene id: 338966:PPRO_RS11415
uniprot id: A1ARE2
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

338966:PPRO RS14995
gene id: 338966:PPRO_RS14995
uniprot id: A1ATE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

338966:PPRO RS06110
gene id: 338966:PPRO_RS06110
uniprot id: A1ANE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CbiN family.
messages: Cell inner membrane
messages: Forms an energy-coupling factor (ECF) transporter complex composed of an ATP-binding protein (A component, CbiO), a transmembrane protein (T component, CbiQ) and 2 possible substrate-capture proteins (S components, CbiM and CbiN) of unknown stoichimetry.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.

338966:PPRO RS00065
gene id: 338966:PPRO_RS00065
uniprot id: A1AJY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

338966:PPRO RS12575
gene id: 338966:PPRO_RS12575
uniprot id: A1AS30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

338966:PPRO RS02720
gene id: 338966:PPRO_RS02720
uniprot id: A1ALG8
names: Subcellular Location Annotation
messages: Cytoplasm

338966:PPRO RS16395
gene id: 338966:PPRO_RS16395
uniprot id: A1AU64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

338966:PPRO RS15805
gene id: 338966:PPRO_RS15805
uniprot id: A1ATU9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

338966:PPRO RS02620
gene id: 338966:PPRO_RS02620
uniprot id: A1ALE5
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

338966:PPRO RS14785
gene id: 338966:PPRO_RS14785
uniprot id: A1ATA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

338966:PPRO RS09150
gene id: 338966:PPRO_RS09150
uniprot id: A1AQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

338966:PPRO RS03195
gene id: 338966:PPRO_RS03195
uniprot id: A1ALR6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS16415
gene id: 338966:PPRO_RS16415
uniprot id: A1AU68
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17255
gene id: 338966:PPRO_RS17255
uniprot id: A1AUP0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

338966:PPRO RS08120
gene id: 338966:PPRO_RS08120
uniprot id: A1ALP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS04670
gene id: 338966:PPRO_RS04670
uniprot id: A1AML4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Membrane
messages: Monomer.

338966:PPRO RS17120
gene id: 338966:PPRO_RS17120
uniprot id: A1AUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

338966:PPRO RS03015
gene id: 338966:PPRO_RS03015
uniprot id: A1ALN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS10265
gene id: 338966:PPRO_RS10265
uniprot id: A1AQQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

338966:PPRO RS17480
gene id: 338966:PPRO_RS17480
uniprot id: A1AUT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

338966:PPRO RS10125
gene id: 338966:PPRO_RS10125
uniprot id: A1AQM9
names: Similarity
messages: Belongs to the peptidase C40 family.

338966:PPRO RS15920
gene id: 338966:PPRO_RS15920
uniprot id: A1ATX2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS16085
gene id: 338966:PPRO_RS16085
uniprot id: A1AU04
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338966:PPRO RS09555
gene id: 338966:PPRO_RS09555
uniprot id: A1ALN5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

338966:PPRO RS07255
gene id: 338966:PPRO_RS07255
uniprot id: A1AP04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

338966:PPRO RS10200
gene id: 338966:PPRO_RS10200
uniprot id: A1AQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS14100
gene id: 338966:PPRO_RS14100
uniprot id: A1ASX3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

338966:PPRO RS15225
gene id: 338966:PPRO_RS15225
uniprot id: A1ATI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

338966:PPRO RS14455
gene id: 338966:PPRO_RS14455
uniprot id: A1AT42
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

338966:PPRO RS17800
gene id: 338966:PPRO_RS17800
uniprot id: A1AUZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

338966:PPRO RS09380
gene id: 338966:PPRO_RS09380
uniprot id: A1AQ77
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

338966:PPRO RS16530
gene id: 338966:PPRO_RS16530
uniprot id: A1AU91
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

338966:PPRO RS13345
gene id: 338966:PPRO_RS13345
uniprot id: A1ASH8
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17370
gene id: 338966:PPRO_RS17370
uniprot id: A1AUR2
names: Similarity
messages: Belongs to the NifX/NifY family.

338966:PPRO RS03095
gene id: 338966:PPRO_RS03095
uniprot id: A1ALP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

338966:PPRO RS00140
gene id: 338966:PPRO_RS00140
uniprot id: A1AJZ8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338966:PPRO RS03395
gene id: 338966:PPRO_RS03395
uniprot id: A1ALV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

338966:PPRO RS04255
gene id: 338966:PPRO_RS04255
uniprot id: A1AMC7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS07085
gene id: 338966:PPRO_RS07085
uniprot id: A1ANX1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

338966:PPRO RS08095
gene id: 338966:PPRO_RS08095
uniprot id: A1ALP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS10510
gene id: 338966:PPRO_RS10510
uniprot id: A1AQV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

338966:PPRO RS15785
gene id: 338966:PPRO_RS15785
uniprot id: A1ATU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

338966:PPRO RS08880
gene id: 338966:PPRO_RS08880
uniprot id: A1APX5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

338966:PPRO RS11740
gene id: 338966:PPRO_RS11740
uniprot id: A1ARK6
names: Subcellular Location Annotation
messages: Secreted

338966:PPRO RS10410
gene id: 338966:PPRO_RS10410
uniprot id: A1AQT5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

338966:PPRO RS16100
gene id: 338966:PPRO_RS16100
uniprot id: A1AU06
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS06320
gene id: 338966:PPRO_RS06320
uniprot id: A1ANI2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

338966:PPRO RS15710
gene id: 338966:PPRO_RS15710
uniprot id: A1ATT0
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

338966:PPRO RS08420
gene id: 338966:PPRO_RS08420
uniprot id: A1APN2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

338966:PPRO RS08480
gene id: 338966:PPRO_RS08480
uniprot id: A1APP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

338966:PPRO RS02980
gene id: 338966:PPRO_RS02980
uniprot id: A1ALM4
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

338966:PPRO RS16675
gene id: 338966:PPRO_RS16675
uniprot id: A1AUC0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338966:PPRO RS14410
gene id: 338966:PPRO_RS14410
uniprot id: A1AT33
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17975
gene id: 338966:PPRO_RS17975
uniprot id: A1AV35
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

338966:PPRO RS00475
gene id: 338966:PPRO_RS00475
uniprot id: A1AK64
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

338966:PPRO RS02875
gene id: 338966:PPRO_RS02875
uniprot id: A1ALK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

338966:PPRO RS11420
gene id: 338966:PPRO_RS11420
uniprot id: A1ARE3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

338966:PPRO RS12990
gene id: 338966:PPRO_RS12990
uniprot id: A1ASB9
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS06640
gene id: 338966:PPRO_RS06640
uniprot id: A1ANN8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

338966:PPRO RS18665
gene id: 338966:PPRO_RS18665
uniprot id: A0R7V1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS08130
gene id: 338966:PPRO_RS08130
uniprot id: A1ALP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS17185
gene id: 338966:PPRO_RS17185
uniprot id: A1AUM7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

338966:PPRO RS02210
gene id: 338966:PPRO_RS02210
uniprot id: A1AL64
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

338966:PPRO RS18165
gene id: 338966:PPRO_RS18165
uniprot id: A0R7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

338966:PPRO RS03915
gene id: 338966:PPRO_RS03915
uniprot id: A1AM60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

338966:PPRO RS13860
gene id: 338966:PPRO_RS13860
uniprot id: A1ASR7
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

338966:PPRO RS07935
gene id: 338966:PPRO_RS07935
uniprot id: A1APD8
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

338966:PPRO RS17565
gene id: 338966:PPRO_RS17565
uniprot id: A1AUV2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14685
gene id: 338966:PPRO_RS14685
uniprot id: A1AT86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

338966:PPRO RS16845
gene id: 338966:PPRO_RS16845
uniprot id: A1AUF5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

338966:PPRO RS16490
gene id: 338966:PPRO_RS16490
uniprot id: A1AU82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS06870
gene id: 338966:PPRO_RS06870
uniprot id: A1ANS7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS03600
gene id: 338966:PPRO_RS03600
uniprot id: A1ALZ6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS16310
gene id: 338966:PPRO_RS16310
uniprot id: A1AU47
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

338966:PPRO RS08845
gene id: 338966:PPRO_RS08845
uniprot id: A1APW8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

338966:PPRO RS15885
gene id: 338966:PPRO_RS15885
uniprot id: A1ALP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

338966:PPRO RS15145
gene id: 338966:PPRO_RS15145
uniprot id: A1ATH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

338966:PPRO RS12540
gene id: 338966:PPRO_RS12540
uniprot id: A1AS22
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

338966:PPRO RS13355
gene id: 338966:PPRO_RS13355
uniprot id: A1ASI0
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08685
gene id: 338966:PPRO_RS08685
uniprot id: A1APT5
names: Similarity
messages: Belongs to the fabD family.

338966:PPRO RS10820
gene id: 338966:PPRO_RS10820
uniprot id: A1AR17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

338966:PPRO RS15265
gene id: 338966:PPRO_RS15265
uniprot id: A1ATJ6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

338966:PPRO RS08285
gene id: 338966:PPRO_RS08285
uniprot id: A1APL0
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

338966:PPRO RS01635
gene id: 338966:PPRO_RS01635
uniprot id: A1AKV1
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS01995
gene id: 338966:PPRO_RS01995
uniprot id: A1AL24
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS07925
gene id: 338966:PPRO_RS07925
uniprot id: A1APD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

338966:PPRO RS15025
gene id: 338966:PPRO_RS15025
uniprot id: A1ATF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

338966:PPRO RS08035
gene id: 338966:PPRO_RS08035
uniprot id: A1APF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

338966:PPRO RS12490
gene id: 338966:PPRO_RS12490
uniprot id: A1AS12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

338966:PPRO RS17085
gene id: 338966:PPRO_RS17085
uniprot id: A1AUK7
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

338966:PPRO RS08465
gene id: 338966:PPRO_RS08465
uniprot id: A1APP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

338966:PPRO RS03920
gene id: 338966:PPRO_RS03920
uniprot id: A1AM61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

338966:PPRO RS00200
gene id: 338966:PPRO_RS00200
uniprot id: A1AK11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

338966:PPRO RS08175
gene id: 338966:PPRO_RS08175
uniprot id: A1API7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS03710
gene id: 338966:PPRO_RS03710
uniprot id: A1AM18
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

338966:PPRO RS16150
gene id: 338966:PPRO_RS16150
uniprot id: A1AU16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS16300
gene id: 338966:PPRO_RS16300
uniprot id: A1AU45
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS16075
gene id: 338966:PPRO_RS16075
uniprot id: A1AU02
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

338966:PPRO RS20635
gene id: 338966:PPRO_RS20635
uniprot id: A1ATI7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

338966:PPRO RS09765
gene id: 338966:PPRO_RS09765
uniprot id: A1AQF7
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

338966:PPRO RS17200
gene id: 338966:PPRO_RS17200
uniprot id: A1AUN0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

338966:PPRO RS14700
gene id: 338966:PPRO_RS14700
uniprot id: A1AT89
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

338966:PPRO RS02895
gene id: 338966:PPRO_RS02895
uniprot id: A1ALK7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14810
gene id: 338966:PPRO_RS14810
uniprot id: A1ATB2
names: Similarity
messages: Belongs to the peptidase S49 family.

338966:PPRO RS01675
gene id: 338966:PPRO_RS01675
uniprot id: A1AKV9
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

338966:PPRO RS04090
gene id: 338966:PPRO_RS04090
uniprot id: A1AM94
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

338966:PPRO RS21595
gene id: 338966:PPRO_RS21595
uniprot id: A1AMD4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS07650
gene id: 338966:PPRO_RS07650
uniprot id: A1AP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrC/TusE family.
messages: Cytoplasm

338966:PPRO RS08665
gene id: 338966:PPRO_RS08665
uniprot id: A1APT0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

338966:PPRO RS05975
gene id: 338966:PPRO_RS05975
uniprot id: A1ANB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

338966:PPRO RS00225
gene id: 338966:PPRO_RS00225
uniprot id: A1AK16
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

338966:PPRO RS01370
gene id: 338966:PPRO_RS01370
uniprot id: A1AKQ0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

338966:PPRO RS10455
gene id: 338966:PPRO_RS10455
uniprot id: A1AQU5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

338966:PPRO RS07485
gene id: 338966:PPRO_RS07485
uniprot id: A1ALL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

338966:PPRO RS04695
gene id: 338966:PPRO_RS04695
uniprot id: A1AML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

338966:PPRO RS10825
gene id: 338966:PPRO_RS10825
uniprot id: A1AR18
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338966:PPRO RS11220
gene id: 338966:PPRO_RS11220
uniprot id: A1AR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

338966:PPRO RS11105
gene id: 338966:PPRO_RS11105
uniprot id: A1AR76
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

338966:PPRO RS05910
gene id: 338966:PPRO_RS05910
uniprot id: A1ANA1
names: Similarity
messages: Belongs to the cytochrome c-552 family.

338966:PPRO RS04120
gene id: 338966:PPRO_RS04120
uniprot id: A1AMA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS16390
gene id: 338966:PPRO_RS16390
uniprot id: A1AU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

338966:PPRO RS08990
gene id: 338966:PPRO_RS08990
uniprot id: A1APZ7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS15175
gene id: 338966:PPRO_RS15175
uniprot id: A1ATI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

338966:PPRO RS06700
gene id: 338966:PPRO_RS06700
uniprot id: A1ANQ0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

338966:PPRO RS05810
gene id: 338966:PPRO_RS05810
uniprot id: A1AN86
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

338966:PPRO RS09775
gene id: 338966:PPRO_RS09775
uniprot id: A1AQF9
names: Similarity
messages: Belongs to the leucine-binding protein family.

338966:PPRO RS07610
gene id: 338966:PPRO_RS07610
uniprot id: A1AP74
names: Similarity
messages: Belongs to the ModE family.

338966:PPRO RS05725
gene id: 338966:PPRO_RS05725
uniprot id: A1AN70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

338966:PPRO RS16000
gene id: 338966:PPRO_RS16000
uniprot id: A1ATY8
names: Similarity
messages: Belongs to the peptidase M16 family.

338966:PPRO RS03265
gene id: 338966:PPRO_RS03265
uniprot id: A1ALS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

338966:PPRO RS14460
gene id: 338966:PPRO_RS14460
uniprot id: A1AT43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

338966:PPRO RS03755
gene id: 338966:PPRO_RS03755
uniprot id: A1AM27
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS00690
gene id: 338966:PPRO_RS00690
uniprot id: A1AKA8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS10175
gene id: 338966:PPRO_RS10175
uniprot id: A1AQN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

338966:PPRO RS04140
gene id: 338966:PPRO_RS04140
uniprot id: A1AMA4
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

338966:PPRO RS06080
gene id: 338966:PPRO_RS06080
uniprot id: A1AND5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338966:PPRO RS13215
gene id: 338966:PPRO_RS13215
uniprot id: A1ASF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

338966:PPRO RS02375
gene id: 338966:PPRO_RS02375
uniprot id: A1AL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS03055
gene id: 338966:PPRO_RS03055
uniprot id: A1ALN8
names: Similarity
messages: Belongs to the CinA family.

338966:PPRO RS08555
gene id: 338966:PPRO_RS08555
uniprot id: A1APQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

338966:PPRO RS15195
gene id: 338966:PPRO_RS15195
uniprot id: A1ATI5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338966:PPRO RS09825
gene id: 338966:PPRO_RS09825
uniprot id: A1AQG9
names: Similarity
messages: Belongs to the YciI family.

338966:PPRO RS14615
gene id: 338966:PPRO_RS14615
uniprot id: A1AT72
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

338966:PPRO RS08855
gene id: 338966:PPRO_RS08855
uniprot id: A1APX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

338966:PPRO RS01730
gene id: 338966:PPRO_RS01730
uniprot id: A1AKW9
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

338966:PPRO RS05350
gene id: 338966:PPRO_RS05350
uniprot id: A1AMZ8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

338966:PPRO RS19105
gene id: 338966:PPRO_RS19105
uniprot id: A0R849
names: Similarity
messages: Belongs to the transposase 7 family.

338966:PPRO RS17130
gene id: 338966:PPRO_RS17130
uniprot id: A1AUL6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

338966:PPRO RS15795
gene id: 338966:PPRO_RS15795
uniprot id: A1ATU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

338966:PPRO RS07260
gene id: 338966:PPRO_RS07260
uniprot id: A1AP05
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338966:PPRO RS03715
gene id: 338966:PPRO_RS03715
uniprot id: A1AM19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

338966:PPRO RS16805
gene id: 338966:PPRO_RS16805
uniprot id: A1AUE7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

338966:PPRO RS14350
gene id: 338966:PPRO_RS14350
uniprot id: A1AT21
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

338966:PPRO RS18075
gene id: 338966:PPRO_RS18075
uniprot id: A0R7L6
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS06835
gene id: 338966:PPRO_RS06835
uniprot id: A1ANS0
names: Similarity
messages: Belongs to the DEAD box helicase family.

338966:PPRO RS16350
gene id: 338966:PPRO_RS16350
uniprot id: A1AU55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

338966:PPRO RS00110
gene id: 338966:PPRO_RS00110
uniprot id: A1AJZ3
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338966:PPRO RS08550
gene id: 338966:PPRO_RS08550
uniprot id: A1APQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

338966:PPRO RS01440
gene id: 338966:PPRO_RS01440
uniprot id: A1AKR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

338966:PPRO RS16040
gene id: 338966:PPRO_RS16040
uniprot id: A1ATZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS03100
gene id: 338966:PPRO_RS03100
uniprot id: A1ALP7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS01435
gene id: 338966:PPRO_RS01435
uniprot id: A1AKR3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

338966:PPRO RS05330
gene id: 338966:PPRO_RS05330
uniprot id: A1AMZ4
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

338966:PPRO RS12775
gene id: 338966:PPRO_RS12775
uniprot id: A1AS72
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14805
gene id: 338966:PPRO_RS14805
uniprot id: A1ATB1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

338966:PPRO RS09550
gene id: 338966:PPRO_RS09550
uniprot id: A1AQB4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338966:PPRO RS06715
gene id: 338966:PPRO_RS06715
uniprot id: A1ANQ2
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

338966:PPRO RS17750
gene id: 338966:PPRO_RS17750
uniprot id: A1AUZ0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS20630
gene id: 338966:PPRO_RS20630
uniprot id: A1ATI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

338966:PPRO RS09485
gene id: 338966:PPRO_RS09485
uniprot id: A1AQA1
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS02955
gene id: 338966:PPRO_RS02955
uniprot id: A1ALL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

338966:PPRO RS17520
gene id: 338966:PPRO_RS17520
uniprot id: A1AUU3
names: Similarity
messages: Belongs to the peptidase A31 family.

338966:PPRO RS08600
gene id: 338966:PPRO_RS08600
uniprot id: A1APR7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338966:PPRO RS13040
gene id: 338966:PPRO_RS13040
uniprot id: A1ASC9
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

338966:PPRO RS03570
gene id: 338966:PPRO_RS03570
uniprot id: A1ALZ0
names: Similarity
messages: Belongs to the glutamate synthase family.

338966:PPRO RS00480
gene id: 338966:PPRO_RS00480
uniprot id: A1AK65
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

338966:PPRO RS03480
gene id: 338966:PPRO_RS03480
uniprot id: A1ALX2
names: Similarity
messages: Belongs to the TrpC family.

338966:PPRO RS16470
gene id: 338966:PPRO_RS16470
uniprot id: A1AU78
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

338966:PPRO RS11690
gene id: 338966:PPRO_RS11690
uniprot id: A1ARJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

338966:PPRO RS09315
gene id: 338966:PPRO_RS09315
uniprot id: A1AQ63
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338966:PPRO RS16985
gene id: 338966:PPRO_RS16985
uniprot id: A1AUI7
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

338966:PPRO RS11205
gene id: 338966:PPRO_RS11205
uniprot id: A1AR95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

338966:PPRO RS02680
gene id: 338966:PPRO_RS02680
uniprot id: A1ALF7
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS10340
gene id: 338966:PPRO_RS10340
uniprot id: A1AQS2
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family.

338966:PPRO RS14680
gene id: 338966:PPRO_RS14680
uniprot id: A1AT85
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

338966:PPRO RS14010
gene id: 338966:PPRO_RS14010
uniprot id: A1ASV5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS14220
gene id: 338966:PPRO_RS14220
uniprot id: A1ASZ5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338966:PPRO RS09515
gene id: 338966:PPRO_RS09515
uniprot id: A0R854
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS02830
gene id: 338966:PPRO_RS02830
uniprot id: A1ALJ1
names: Similarity
messages: Belongs to the AOR/FOR family.

338966:PPRO RS15090
gene id: 338966:PPRO_RS15090
uniprot id: A1ATG8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

338966:PPRO RS04150
gene id: 338966:PPRO_RS04150
uniprot id: A1AMA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338966:PPRO RS15015
gene id: 338966:PPRO_RS15015
uniprot id: A1ATF2
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS17575
gene id: 338966:PPRO_RS17575
uniprot id: A1AUV4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS08050
gene id: 338966:PPRO_RS08050
uniprot id: A1APG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338966:PPRO RS13140
gene id: 338966:PPRO_RS13140
uniprot id: A1ASE3
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

338966:PPRO RS17260
gene id: 338966:PPRO_RS17260
uniprot id: A1AUP1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

338966:PPRO RS08895
gene id: 338966:PPRO_RS08895
uniprot id: A1APX8
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

338966:PPRO RS12790
gene id: 338966:PPRO_RS12790
uniprot id: A1AS75
names: Similarity
messages: Belongs to the GARS family.

338966:PPRO RS17920
gene id: 338966:PPRO_RS17920
uniprot id: A1AV24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.

338966:PPRO RS15185
gene id: 338966:PPRO_RS15185
uniprot id: A1ATI3
names: Similarity
messages: Belongs to the hemerythrin family.
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS12195
gene id: 338966:PPRO_RS12195
uniprot id: A1ARV1
names: Similarity
messages: Belongs to the asparagine synthetase family.

338966:PPRO RS02130
gene id: 338966:PPRO_RS02130
uniprot id: A1AL49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

338966:PPRO RS07960
gene id: 338966:PPRO_RS07960
uniprot id: A1APE3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

338966:PPRO RS12350
gene id: 338966:PPRO_RS12350
uniprot id: A1ARY3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

338966:PPRO RS16030
gene id: 338966:PPRO_RS16030
uniprot id: A1ATZ3
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS00315
gene id: 338966:PPRO_RS00315
uniprot id: A1AK34
names: Function
names: Similarity
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.

338966:PPRO RS05250
gene id: 338966:PPRO_RS05250
uniprot id: A1AMX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

338966:PPRO RS03270
gene id: 338966:PPRO_RS03270
uniprot id: A1ALS7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

338966:PPRO RS14245
gene id: 338966:PPRO_RS14245
uniprot id: A1AT00
names: Similarity
messages: Belongs to the FemABX family.

338966:PPRO RS19625
gene id: 338966:PPRO_RS19625
uniprot id: A1ASE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

338966:PPRO RS18450
gene id: 338966:PPRO_RS18450
uniprot id: A0R7X5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS03905
gene id: 338966:PPRO_RS03905
uniprot id: A1AM58
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

338966:PPRO RS18130
gene id: 338966:PPRO_RS18130
uniprot id: A0R7M5
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS06565
gene id: 338966:PPRO_RS06565
uniprot id: A1ANM5
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS06620
gene id: 338966:PPRO_RS06620
uniprot id: A1ANN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

338966:PPRO RS08010
gene id: 338966:PPRO_RS08010
uniprot id: A1APF3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338966:PPRO RS02560
gene id: 338966:PPRO_RS02560
uniprot id: A1ALD3
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

338966:PPRO RS13310
gene id: 338966:PPRO_RS13310
uniprot id: A1ASH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

338966:PPRO RS04245
gene id: 338966:PPRO_RS04245
uniprot id: A1AMC5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

338966:PPRO RS14915
gene id: 338966:PPRO_RS14915
uniprot id: A1ATD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

338966:PPRO RS11860
gene id: 338966:PPRO_RS11860
uniprot id: A1ARN3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

338966:PPRO RS12745
gene id: 338966:PPRO_RS12745
uniprot id: A1AS66
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

338966:PPRO RS02925
gene id: 338966:PPRO_RS02925
uniprot id: A1ALL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338966:PPRO RS11935
gene id: 338966:PPRO_RS11935
uniprot id: A1ARP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

338966:PPRO RS07955
gene id: 338966:PPRO_RS07955
uniprot id: A1APE2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

338966:PPRO RS00470
gene id: 338966:PPRO_RS00470
uniprot id: A1AK63
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

338966:PPRO RS03345
gene id: 338966:PPRO_RS03345
uniprot id: A1ALU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

338966:PPRO RS19770
gene id: 338966:PPRO_RS19770
uniprot id: A1ALP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS02040
gene id: 338966:PPRO_RS02040
uniprot id: A1AL33
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

338966:PPRO RS18160
gene id: 338966:PPRO_RS18160
uniprot id: A0R7N1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338966:PPRO RS03805
gene id: 338966:PPRO_RS03805
uniprot id: A1AM39
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338966:PPRO RS09430
gene id: 338966:PPRO_RS09430
uniprot id: A1AQ91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

338966:PPRO RS19420
gene id: 338966:PPRO_RS19420
uniprot id: A1AP13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

338966:PPRO RS14335
gene id: 338966:PPRO_RS14335
uniprot id: A1AT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

338966:PPRO RS10065
gene id: 338966:PPRO_RS10065
uniprot id: A1AQL6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

338966:PPRO RS12960
gene id: 338966:PPRO_RS12960
uniprot id: A1ASB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
messages: Cytoplasm
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.

338966:PPRO RS05825
gene id: 338966:PPRO_RS05825
uniprot id: A1AN88
names: Similarity
messages: Belongs to the UPF0102 family.

338966:PPRO RS04170
gene id: 338966:PPRO_RS04170
uniprot id: A1AMB0
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

338966:PPRO RS15820
gene id: 338966:PPRO_RS15820
uniprot id: A1ATV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

338966:PPRO RS08085
gene id: 338966:PPRO_RS08085
uniprot id: A1ALP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

338966:PPRO RS03110
gene id: 338966:PPRO_RS03110
uniprot id: A1ALP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338966:PPRO RS12310
gene id: 338966:PPRO_RS12310
uniprot id: A1ARX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

338966:PPRO RS16785
gene id: 338966:PPRO_RS16785
uniprot id: A1AUE3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

338966:PPRO RS13615
gene id: 338966:PPRO_RS13615
uniprot id: A1ASM7
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

338966:PPRO RS08045
gene id: 338966:PPRO_RS08045
uniprot id: A1APG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

338966:PPRO RS08280
gene id: 338966:PPRO_RS08280
uniprot id: A1APK9
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

338966:PPRO RS10060
gene id: 338966:PPRO_RS10060
uniprot id: A1AQL5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

338966:PPRO RS17640
gene id: 338966:PPRO_RS17640
uniprot id: A1AUW8
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS10000
gene id: 338966:PPRO_RS10000
uniprot id: A1AQK3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

338966:PPRO RS18985
gene id: 338966:PPRO_RS18985
uniprot id: A0R7U3
names: Similarity
messages: Belongs to the ParB family.

338966:PPRO RS16420
gene id: 338966:PPRO_RS16420
uniprot id: A1AU69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

338966:PPRO RS12440
gene id: 338966:PPRO_RS12440
uniprot id: A1AS02
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

338966:PPRO RS16330
gene id: 338966:PPRO_RS16330
uniprot id: A1AU51
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

338966:PPRO RS13890
gene id: 338966:PPRO_RS13890
uniprot id: A1AST2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

338966:PPRO RS17450
gene id: 338966:PPRO_RS17450
uniprot id: A1AUS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

338966:PPRO RS03995
gene id: 338966:PPRO_RS03995
uniprot id: A1AM76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

338966:PPRO RS03200
gene id: 338966:PPRO_RS03200
uniprot id: A1ALR7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

338966:PPRO RS07010
gene id: 338966:PPRO_RS07010
uniprot id: A1ANV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

338966:PPRO RS01505
gene id: 338966:PPRO_RS01505
uniprot id: A1AKS6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

338966:PPRO RS02195
gene id: 338966:PPRO_RS02195
uniprot id: A1AL61
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

338966:PPRO RS05375
gene id: 338966:PPRO_RS05375
uniprot id: A1AN03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

338966:PPRO RS11545
gene id: 338966:PPRO_RS11545
uniprot id: A1ARG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

338966:PPRO RS16025
gene id: 338966:PPRO_RS16025
uniprot id: A1ATZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338966:PPRO RS12435
gene id: 338966:PPRO_RS12435
uniprot id: A1AS01
names: Similarity
messages: Belongs to the ribF family.

338966:PPRO RS01690
gene id: 338966:PPRO_RS01690
uniprot id: A1AKW2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

338966:PPRO RS08965
gene id: 338966:PPRO_RS08965
uniprot id: A1APZ2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

338966:PPRO RS14645
gene id: 338966:PPRO_RS14645
uniprot id: A1AT78
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338966:PPRO RS12420
gene id: 338966:PPRO_RS12420
uniprot id: A1ARZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

338966:PPRO RS16035
gene id: 338966:PPRO_RS16035
uniprot id: A1ATZ4
names: Subcellular Location Annotation
messages: Membrane

338966:PPRO RS00760
gene id: 338966:PPRO_RS00760
uniprot id: A1AKC3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

338966:PPRO RS08830
gene id: 338966:PPRO_RS08830
uniprot id: A1APW5
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

338966:PPRO RS13205
gene id: 338966:PPRO_RS13205
uniprot id: A1ASF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

338966:PPRO RS14415
gene id: 338966:PPRO_RS14415
uniprot id: A1AT34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane