338963:PCAR RS13865
gene id: 338963:PCAR_RS13865
uniprot id: Q3A1H6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

338963:PCAR RS01605
gene id: 338963:PCAR_RS01605
uniprot id: Q3A830
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS08440
gene id: 338963:PCAR_RS08440
uniprot id: Q3A4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338963:PCAR RS16170
gene id: 338963:PCAR_RS16170
uniprot id: Q3A079
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

338963:PCAR RS12735
gene id: 338963:PCAR_RS12735
uniprot id: Q3A234
names: Similarity
messages: Belongs to the FBPase class 2 family.

338963:PCAR RS07540
gene id: 338963:PCAR_RS07540
uniprot id: Q3A4X0
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

338963:PCAR RS13725
gene id: 338963:PCAR_RS13725
uniprot id: Q3A1K3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

338963:PCAR RS15925
gene id: 338963:PCAR_RS15925
uniprot id: Q3A0C8
names: Similarity
messages: Belongs to the glutamate synthase family.

338963:PCAR RS16940
gene id: 338963:PCAR_RS16940
uniprot id: Q39ZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338963:PCAR RS08465
gene id: 338963:PCAR_RS08465
uniprot id: Q3A4F1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

338963:PCAR RS13910
gene id: 338963:PCAR_RS13910
uniprot id: Q3A1G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

338963:PCAR RS04350
gene id: 338963:PCAR_RS04350
uniprot id: Q3A6N3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

338963:PCAR RS04970
gene id: 338963:PCAR_RS04970
uniprot id: Q3A6B8
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

338963:PCAR RS14315
gene id: 338963:PCAR_RS14315
uniprot id: Q3A191
names: Similarity
messages: Belongs to the glutamate synthase family.

338963:PCAR RS04305
gene id: 338963:PCAR_RS04305
uniprot id: Q3A6P3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

338963:PCAR RS04080
gene id: 338963:PCAR_RS04080
uniprot id: Q3A6T3
names: Similarity
messages: Belongs to the AOR/FOR family.

338963:PCAR RS08395
gene id: 338963:PCAR_RS08395
uniprot id: Q3A4G5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338963:PCAR RS07395
gene id: 338963:PCAR_RS07395
uniprot id: Q3A4Z6
names: Subcellular Location Annotation
messages: Nucleus

338963:PCAR RS10855
gene id: 338963:PCAR_RS10855
uniprot id: Q3A347
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

338963:PCAR RS01730
gene id: 338963:PCAR_RS01730
uniprot id: Q3A812
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338963:PCAR RS01120
gene id: 338963:PCAR_RS01120
uniprot id: Q3A8C0
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

338963:PCAR RS13210
gene id: 338963:PCAR_RS13210
uniprot id: Q3A1V1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

338963:PCAR RS11945
gene id: 338963:PCAR_RS11945
uniprot id: Q3A2I8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

338963:PCAR RS08610
gene id: 338963:PCAR_RS08610
uniprot id: Q3A4C3
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10860
gene id: 338963:PCAR_RS10860
uniprot id: Q3A346
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS05825
gene id: 338963:PCAR_RS05825
uniprot id: Q3A5V5
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

338963:PCAR RS14590
gene id: 338963:PCAR_RS14590
uniprot id: Q3A140
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07110
gene id: 338963:PCAR_RS07110
uniprot id: Q3A553
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

338963:PCAR RS11060
gene id: 338963:PCAR_RS11060
uniprot id: Q3A309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

338963:PCAR RS12865
gene id: 338963:PCAR_RS12865
uniprot id: Q3A218
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

338963:PCAR RS06375
gene id: 338963:PCAR_RS06375
uniprot id: Q3A5J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

338963:PCAR RS03770
gene id: 338963:PCAR_RS03770
uniprot id: Q3A6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

338963:PCAR RS17860
gene id: 338963:PCAR_RS17860
uniprot id: Q3A3Q5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS00700
gene id: 338963:PCAR_RS00700
uniprot id: Q3A8K1
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

338963:PCAR RS12650
gene id: 338963:PCAR_RS12650
uniprot id: Q3A251
names: Similarity
messages: Belongs to the ros/MucR family.

338963:PCAR RS06010
gene id: 338963:PCAR_RS06010
uniprot id: Q3A5S0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

338963:PCAR RS06330
gene id: 338963:PCAR_RS06330
uniprot id: Q3A5K5
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

338963:PCAR RS08700
gene id: 338963:PCAR_RS08700
uniprot id: Q3A4A5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

338963:PCAR RS14585
gene id: 338963:PCAR_RS14585
uniprot id: Q3A141
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

338963:PCAR RS03935
gene id: 338963:PCAR_RS03935
uniprot id: Q3A6W1
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS04155
gene id: 338963:PCAR_RS04155
uniprot id: Q3A6R8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS01000
gene id: 338963:PCAR_RS01000
uniprot id: Q3A8E3
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS06750
gene id: 338963:PCAR_RS06750
uniprot id: Q3A5C3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

338963:PCAR RS10895
gene id: 338963:PCAR_RS10895
uniprot id: Q3A339
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS11000
gene id: 338963:PCAR_RS11000
uniprot id: Q3A320
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

338963:PCAR RS04980
gene id: 338963:PCAR_RS04980
uniprot id: Q3A6B7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338963:PCAR RS02070
gene id: 338963:PCAR_RS02070
uniprot id: Q3A7U7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS15195
gene id: 338963:PCAR_RS15195
uniprot id: Q3A0S0
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

338963:PCAR RS13350
gene id: 338963:PCAR_RS13350
uniprot id: Q3A1S3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

338963:PCAR RS03965
gene id: 338963:PCAR_RS03965
uniprot id: Q3A6V5
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

338963:PCAR RS07140
gene id: 338963:PCAR_RS07140
uniprot id: Q3A547
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

338963:PCAR RS09725
gene id: 338963:PCAR_RS09725
uniprot id: Q3A3R7
names: Similarity
messages: Belongs to the bacterial secretin family.

338963:PCAR RS10220
gene id: 338963:PCAR_RS10220
uniprot id: Q3A3H2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338963:PCAR RS16890
gene id: 338963:PCAR_RS16890
uniprot id: Q39ZU7
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

338963:PCAR RS05835
gene id: 338963:PCAR_RS05835
uniprot id: Q3A5V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

338963:PCAR RS10965
gene id: 338963:PCAR_RS10965
uniprot id: Q3A327
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338963:PCAR RS05395
gene id: 338963:PCAR_RS05395
uniprot id: Q3A639
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338963:PCAR RS09490
gene id: 338963:PCAR_RS09490
uniprot id: Q3A3W3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338963:PCAR RS02900
gene id: 338963:PCAR_RS02900
uniprot id: Q3A7E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

338963:PCAR RS07490
gene id: 338963:PCAR_RS07490
uniprot id: Q3A4Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

338963:PCAR RS04580
gene id: 338963:PCAR_RS04580
uniprot id: Q3A6I7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

338963:PCAR RS12785
gene id: 338963:PCAR_RS12785
uniprot id: Q3A224
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338963:PCAR RS16720
gene id: 338963:PCAR_RS16720
uniprot id: Q39ZX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS13490
gene id: 338963:PCAR_RS13490
uniprot id: Q3A1P6
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS11180
gene id: 338963:PCAR_RS11180
uniprot id: Q3A2Y6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

338963:PCAR RS16345
gene id: 338963:PCAR_RS16345
uniprot id: Q3A045
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS06635
gene id: 338963:PCAR_RS06635
uniprot id: Q3A5E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

338963:PCAR RS09280
gene id: 338963:PCAR_RS09280
uniprot id: Q3A3Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BioW family.
messages: Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
messages: Homodimer.

338963:PCAR RS01110
gene id: 338963:PCAR_RS01110
uniprot id: Q3A8C2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

338963:PCAR RS07075
gene id: 338963:PCAR_RS07075
uniprot id: Q3A560
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS06310
gene id: 338963:PCAR_RS06310
uniprot id: Q3A5K9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS11415
gene id: 338963:PCAR_RS11415
uniprot id: Q3A2U0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338963:PCAR RS16835
gene id: 338963:PCAR_RS16835
uniprot id: Q39ZV7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

338963:PCAR RS11710
gene id: 338963:PCAR_RS11710
uniprot id: Q3A2N5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

338963:PCAR RS12695
gene id: 338963:PCAR_RS12695
uniprot id: Q3A242
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

338963:PCAR RS02495
gene id: 338963:PCAR_RS02495
uniprot id: Q3A7M0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338963:PCAR RS15975
gene id: 338963:PCAR_RS15975
uniprot id: Q3A0B8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

338963:PCAR RS04680
gene id: 338963:PCAR_RS04680
uniprot id: Q3A6H0
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS12170
gene id: 338963:PCAR_RS12170
uniprot id: Q3A2E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

338963:PCAR RS07100
gene id: 338963:PCAR_RS07100
uniprot id: Q3A555
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

338963:PCAR RS12330
gene id: 338963:PCAR_RS12330
uniprot id: Q3A2B3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

338963:PCAR RS10515
gene id: 338963:PCAR_RS10515
uniprot id: Q3A3B4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS03230
gene id: 338963:PCAR_RS03230
uniprot id: Q3A776
names: Similarity
messages: Belongs to the hemerythrin family.

338963:PCAR RS16970
gene id: 338963:PCAR_RS16970
uniprot id: Q39ZT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

338963:PCAR RS01665
gene id: 338963:PCAR_RS01665
uniprot id: Q3A822
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

338963:PCAR RS06950
gene id: 338963:PCAR_RS06950
uniprot id: Q3A584
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RlpA family.
messages: Cell membrane
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

338963:PCAR RS06930
gene id: 338963:PCAR_RS06930
uniprot id: Q3A587
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

338963:PCAR RS10790
gene id: 338963:PCAR_RS10790
uniprot id: Q3A360
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS09755
gene id: 338963:PCAR_RS09755
uniprot id: Q3A3R1
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07530
gene id: 338963:PCAR_RS07530
uniprot id: Q3A4X2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS05850
gene id: 338963:PCAR_RS05850
uniprot id: Q3A5V0
names: Similarity
messages: Belongs to the aspartokinase family.

338963:PCAR RS08915
gene id: 338963:PCAR_RS08915
uniprot id: Q3A464
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS12195
gene id: 338963:PCAR_RS12195
uniprot id: Q3A2E0
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08175
gene id: 338963:PCAR_RS08175
uniprot id: Q3A4K6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338963:PCAR RS08230
gene id: 338963:PCAR_RS08230
uniprot id: Q3A4J5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

338963:PCAR RS09700
gene id: 338963:PCAR_RS09700
uniprot id: Q3A3S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

338963:PCAR RS04175
gene id: 338963:PCAR_RS04175
uniprot id: Q3A6R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

338963:PCAR RS13360
gene id: 338963:PCAR_RS13360
uniprot id: Q3A1S1
names: Function
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family. Butyryl-CoA CoA-transferase subfamily.
messages: Coenzyme A-transferase that converts butyryl-CoA to butyrate.

338963:PCAR RS04335
gene id: 338963:PCAR_RS04335
uniprot id: Q3A6N7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

338963:PCAR RS01870
gene id: 338963:PCAR_RS01870
uniprot id: Q3A7Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

338963:PCAR RS05090
gene id: 338963:PCAR_RS05090
uniprot id: Q3A696
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338963:PCAR RS10650
gene id: 338963:PCAR_RS10650
uniprot id: Q3A387
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

338963:PCAR RS12350
gene id: 338963:PCAR_RS12350
uniprot id: Q3A2A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

338963:PCAR RS01530
gene id: 338963:PCAR_RS01530
uniprot id: Q3A844
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10350
gene id: 338963:PCAR_RS10350
uniprot id: Q3A3E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS15040
gene id: 338963:PCAR_RS15040
uniprot id: Q3A0V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

338963:PCAR RS12435
gene id: 338963:PCAR_RS12435
uniprot id: Q3A292
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

338963:PCAR RS10405
gene id: 338963:PCAR_RS10405
uniprot id: Q3A3D6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338963:PCAR RS15370
gene id: 338963:PCAR_RS15370
uniprot id: Q3A0N5
names: Similarity
messages: Belongs to the band 7/mec-2 family.

338963:PCAR RS06915
gene id: 338963:PCAR_RS06915
uniprot id: Q3A590
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

338963:PCAR RS07830
gene id: 338963:PCAR_RS07830
uniprot id: Q3A4S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

338963:PCAR RS16060
gene id: 338963:PCAR_RS16060
uniprot id: Q3A0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS13275
gene id: 338963:PCAR_RS13275
uniprot id: Q3A1T8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338963:PCAR RS16050
gene id: 338963:PCAR_RS16050
uniprot id: Q3A0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

338963:PCAR RS01650
gene id: 338963:PCAR_RS01650
uniprot id: Q3A825
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the complex I 49 kDa subunit family.
messages: In the N-terminal section; belongs to the complex I 20 kDa subunit family.
messages: In the central section; belongs to the complex I 30 kDa subunit family.
messages: NDH-1 is composed of about 13 different subunits. Subunits NuoBCD, E, F, and G constitute the peripheral sector of the complex (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338963:PCAR RS06190
gene id: 338963:PCAR_RS06190
uniprot id: Q3A5N4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS15580
gene id: 338963:PCAR_RS15580
uniprot id: Q3A0J6
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS06785
gene id: 338963:PCAR_RS06785
uniprot id: Q3A5B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

338963:PCAR RS07360
gene id: 338963:PCAR_RS07360
uniprot id: Q3A503
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

338963:PCAR RS01670
gene id: 338963:PCAR_RS01670
uniprot id: Q3A821
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

338963:PCAR RS02780
gene id: 338963:PCAR_RS02780
uniprot id: Q3A7G5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

338963:PCAR RS08455
gene id: 338963:PCAR_RS08455
uniprot id: Q3A4F3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS15710
gene id: 338963:PCAR_RS15710
uniprot id: Q3A0G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

338963:PCAR RS10470
gene id: 338963:PCAR_RS10470
uniprot id: Q3A3C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

338963:PCAR RS06985
gene id: 338963:PCAR_RS06985
uniprot id: Q3A578
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

338963:PCAR RS03520
gene id: 338963:PCAR_RS03520
uniprot id: Q3A730
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

338963:PCAR RS07580
gene id: 338963:PCAR_RS07580
uniprot id: Q3A4W3
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08335
gene id: 338963:PCAR_RS08335
uniprot id: Q3A4H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

338963:PCAR RS02410
gene id: 338963:PCAR_RS02410
uniprot id: Q3A7N7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

338963:PCAR RS14620
gene id: 338963:PCAR_RS14620
uniprot id: Q3A134
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

338963:PCAR RS16585
gene id: 338963:PCAR_RS16585
uniprot id: Q3A004
names: Similarity
messages: Belongs to the thioredoxin family.

338963:PCAR RS09120
gene id: 338963:PCAR_RS09120
uniprot id: Q3A425
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

338963:PCAR RS08475
gene id: 338963:PCAR_RS08475
uniprot id: Q3A4E9
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

338963:PCAR RS02905
gene id: 338963:PCAR_RS02905
uniprot id: Q3A7E0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

338963:PCAR RS14805
gene id: 338963:PCAR_RS14805
uniprot id: Q3A0Z7
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

338963:PCAR RS16625
gene id: 338963:PCAR_RS16625
uniprot id: Q39ZZ6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

338963:PCAR RS06580
gene id: 338963:PCAR_RS06580
uniprot id: Q3A5F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

338963:PCAR RS06640
gene id: 338963:PCAR_RS06640
uniprot id: Q3A5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

338963:PCAR RS02175
gene id: 338963:PCAR_RS02175
uniprot id: Q3A7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338963:PCAR RS10440
gene id: 338963:PCAR_RS10440
uniprot id: Q3A3C9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

338963:PCAR RS04650
gene id: 338963:PCAR_RS04650
uniprot id: Q3A6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

338963:PCAR RS02400
gene id: 338963:PCAR_RS02400
uniprot id: Q3A7N9
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

338963:PCAR RS08900
gene id: 338963:PCAR_RS08900
uniprot id: Q3A467
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338963:PCAR RS07250
gene id: 338963:PCAR_RS07250
uniprot id: Q3A525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

338963:PCAR RS00640
gene id: 338963:PCAR_RS00640
uniprot id: Q3A8L3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

338963:PCAR RS08585
gene id: 338963:PCAR_RS08585
uniprot id: Q3A4C8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338963:PCAR RS01525
gene id: 338963:PCAR_RS01525
uniprot id: Q3A845
names: Similarity
messages: Belongs to the AdoMet synthetase 2 family.

338963:PCAR RS11605
gene id: 338963:PCAR_RS11605
uniprot id: Q3A2Q2
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

338963:PCAR RS01700
gene id: 338963:PCAR_RS01700
uniprot id: Q3A815
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338963:PCAR RS11570
gene id: 338963:PCAR_RS11570
uniprot id: Q3A2Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

338963:PCAR RS10460
gene id: 338963:PCAR_RS10460
uniprot id: Q3A3C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

338963:PCAR RS12370
gene id: 338963:PCAR_RS12370
uniprot id: Q3A2A5
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

338963:PCAR RS06320
gene id: 338963:PCAR_RS06320
uniprot id: Q3A5K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338963:PCAR RS05275
gene id: 338963:PCAR_RS05275
uniprot id: Q3A661
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS04365
gene id: 338963:PCAR_RS04365
uniprot id: Q3A6N0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

338963:PCAR RS06800
gene id: 338963:PCAR_RS06800
uniprot id: Q3A5B3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

338963:PCAR RS08330
gene id: 338963:PCAR_RS08330
uniprot id: Q3A4H5
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

338963:PCAR RS10195
gene id: 338963:PCAR_RS10195
uniprot id: Q3A3H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

338963:PCAR RS09620
gene id: 338963:PCAR_RS09620
uniprot id: Q3A3T7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

338963:PCAR RS04065
gene id: 338963:PCAR_RS04065
uniprot id: Q3A6T6
names: Similarity
messages: Belongs to the ModE family.

338963:PCAR RS13065
gene id: 338963:PCAR_RS13065
uniprot id: Q3A1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

338963:PCAR RS12610
gene id: 338963:PCAR_RS12610
uniprot id: Q3A258
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

338963:PCAR RS10510
gene id: 338963:PCAR_RS10510
uniprot id: Q3A3B5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

338963:PCAR RS08885
gene id: 338963:PCAR_RS08885
uniprot id: Q3A470
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

338963:PCAR RS07515
gene id: 338963:PCAR_RS07515
uniprot id: Q3A4X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338963:PCAR RS05560
gene id: 338963:PCAR_RS05560
uniprot id: Q39ZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338963:PCAR RS04255
gene id: 338963:PCAR_RS04255
uniprot id: Q3A6Q3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338963:PCAR RS01690
gene id: 338963:PCAR_RS01690
uniprot id: Q3A817
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS01135
gene id: 338963:PCAR_RS01135
uniprot id: Q3A8B7
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

338963:PCAR RS13590
gene id: 338963:PCAR_RS13590
uniprot id: Q3A1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS14095
gene id: 338963:PCAR_RS14095
uniprot id: Q3A1D1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS06650
gene id: 338963:PCAR_RS06650
uniprot id: Q3A5E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

338963:PCAR RS04320
gene id: 338963:PCAR_RS04320
uniprot id: Q3A6P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

338963:PCAR RS14190
gene id: 338963:PCAR_RS14190
uniprot id: Q3A1B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS11785
gene id: 338963:PCAR_RS11785
uniprot id: Q3A2M0
names: Similarity
messages: Belongs to the GSP E family.

338963:PCAR RS02970
gene id: 338963:PCAR_RS02970
uniprot id: Q3A7C8
names: Similarity
messages: Belongs to the AOR/FOR family.

338963:PCAR RS14005
gene id: 338963:PCAR_RS14005
uniprot id: Q3A1E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

338963:PCAR RS11105
gene id: 338963:PCAR_RS11105
uniprot id: Q3A300
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

338963:PCAR RS10495
gene id: 338963:PCAR_RS10495
uniprot id: Q3A3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

338963:PCAR RS04900
gene id: 338963:PCAR_RS04900
uniprot id: Q3A6D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

338963:PCAR RS14650
gene id: 338963:PCAR_RS14650
uniprot id: Q3A128
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

338963:PCAR RS08520
gene id: 338963:PCAR_RS08520
uniprot id: Q3A4E0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

338963:PCAR RS07995
gene id: 338963:PCAR_RS07995
uniprot id: Q3A4P1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

338963:PCAR RS04045
gene id: 338963:PCAR_RS04045
uniprot id: Q3A6U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

338963:PCAR RS10665
gene id: 338963:PCAR_RS10665
uniprot id: Q3A384
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS01835
gene id: 338963:PCAR_RS01835
uniprot id: Q3A7Z1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

338963:PCAR RS16645
gene id: 338963:PCAR_RS16645
uniprot id: Q39ZZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

338963:PCAR RS11670
gene id: 338963:PCAR_RS11670
uniprot id: Q3A2P3
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

338963:PCAR RS04500
gene id: 338963:PCAR_RS04500
uniprot id: Q3A6K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

338963:PCAR RS08300
gene id: 338963:PCAR_RS08300
uniprot id: Q3A4I1
names: Similarity
messages: Belongs to the SUI1 family.

338963:PCAR RS07230
gene id: 338963:PCAR_RS07230
uniprot id: Q3A529
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

338963:PCAR RS17650
gene id: 338963:PCAR_RS17650
uniprot id: Q3A8N7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

338963:PCAR RS06150
gene id: 338963:PCAR_RS06150
uniprot id: Q3A5P2
names: Similarity
messages: Belongs to the UPF0047 family.

338963:PCAR RS16095
gene id: 338963:PCAR_RS16095
uniprot id: Q3A095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338963:PCAR RS09405
gene id: 338963:PCAR_RS09405
uniprot id: Q3A3X8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338963:PCAR RS08140
gene id: 338963:PCAR_RS08140
uniprot id: Q3A4L3
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

338963:PCAR RS11020
gene id: 338963:PCAR_RS11020
uniprot id: Q3A316
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

338963:PCAR RS11115
gene id: 338963:PCAR_RS11115
uniprot id: Q3A2Z8
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

338963:PCAR RS10500
gene id: 338963:PCAR_RS10500
uniprot id: Q3A3B7
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

338963:PCAR RS10015
gene id: 338963:PCAR_RS10015
uniprot id: Q3A3K9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

338963:PCAR RS03270
gene id: 338963:PCAR_RS03270
uniprot id: Q3A768
names: Similarity
messages: Belongs to the YjdM family.

338963:PCAR RS12990
gene id: 338963:PCAR_RS12990
uniprot id: Q3A1Z4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS16140
gene id: 338963:PCAR_RS16140
uniprot id: Q3A085
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

338963:PCAR RS00585
gene id: 338963:PCAR_RS00585
uniprot id: Q3A8M4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

338963:PCAR RS12470
gene id: 338963:PCAR_RS12470
uniprot id: Q3A285
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

338963:PCAR RS06170
gene id: 338963:PCAR_RS06170
uniprot id: Q3A5N8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

338963:PCAR RS08995
gene id: 338963:PCAR_RS08995
uniprot id: Q3A448
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

338963:PCAR RS09865
gene id: 338963:PCAR_RS09865
uniprot id: Q3A3N9
names: Similarity
messages: Belongs to the MlaA family.

338963:PCAR RS06740
gene id: 338963:PCAR_RS06740
uniprot id: Q3A5C5
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

338963:PCAR RS11170
gene id: 338963:PCAR_RS11170
uniprot id: Q3A2Y8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

338963:PCAR RS02155
gene id: 338963:PCAR_RS02155
uniprot id: Q3A7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

338963:PCAR RS09330
gene id: 338963:PCAR_RS09330
uniprot id: Q3A3Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

338963:PCAR RS03225
gene id: 338963:PCAR_RS03225
uniprot id: Q3A777
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS16260
gene id: 338963:PCAR_RS16260
uniprot id: Q3A061
names: Function
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

338963:PCAR RS03820
gene id: 338963:PCAR_RS03820
uniprot id: Q3A6Y4
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

338963:PCAR RS15555
gene id: 338963:PCAR_RS15555
uniprot id: Q3A0K1
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338963:PCAR RS05075
gene id: 338963:PCAR_RS05075
uniprot id: Q3A699
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS07620
gene id: 338963:PCAR_RS07620
uniprot id: Q3A4V6
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07950
gene id: 338963:PCAR_RS07950
uniprot id: Q3A4P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

338963:PCAR RS16615
gene id: 338963:PCAR_RS16615
uniprot id: Q39ZZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS06575
gene id: 338963:PCAR_RS06575
uniprot id: Q3A5F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

338963:PCAR RS12325
gene id: 338963:PCAR_RS12325
uniprot id: Q3A2B4
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338963:PCAR RS13370
gene id: 338963:PCAR_RS13370
uniprot id: Q3A1R9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS06015
gene id: 338963:PCAR_RS06015
uniprot id: Q3A5R9
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

338963:PCAR RS07990
gene id: 338963:PCAR_RS07990
uniprot id: Q3A4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

338963:PCAR RS05535
gene id: 338963:PCAR_RS05535
uniprot id: Q3A611
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

338963:PCAR RS04355
gene id: 338963:PCAR_RS04355
uniprot id: Q3A6N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

338963:PCAR RS11530
gene id: 338963:PCAR_RS11530
uniprot id: Q3A2R7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Binds 1 [8Fe-7S] cluster per heterodimer.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

338963:PCAR RS04960
gene id: 338963:PCAR_RS04960
uniprot id: Q3A6B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338963:PCAR RS03095
gene id: 338963:PCAR_RS03095
uniprot id: Q3A7A3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the CobB/CbiA family.
messages: Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.
messages: Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.
messages: The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.

338963:PCAR RS16180
gene id: 338963:PCAR_RS16180
uniprot id: Q3A077
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338963:PCAR RS11395
gene id: 338963:PCAR_RS11395
uniprot id: Q3A2U4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08025
gene id: 338963:PCAR_RS08025
uniprot id: Q3A4N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

338963:PCAR RS10135
gene id: 338963:PCAR_RS10135
uniprot id: Q3A3I8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

338963:PCAR RS12090
gene id: 338963:PCAR_RS12090
uniprot id: Q3A2G1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS08740
gene id: 338963:PCAR_RS08740
uniprot id: Q3A497
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338963:PCAR RS01025
gene id: 338963:PCAR_RS01025
uniprot id: Q3A8D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

338963:PCAR RS12215
gene id: 338963:PCAR_RS12215
uniprot id: Q3A2D6
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

338963:PCAR RS11680
gene id: 338963:PCAR_RS11680
uniprot id: Q3A2P1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338963:PCAR RS13535
gene id: 338963:PCAR_RS13535
uniprot id: Q3A1N7
names: Similarity
messages: Belongs to the IMPACT family.

338963:PCAR RS02500
gene id: 338963:PCAR_RS02500
uniprot id: Q3A7L9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS16150
gene id: 338963:PCAR_RS16150
uniprot id: Q3A083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338963:PCAR RS03450
gene id: 338963:PCAR_RS03450
uniprot id: Q3A743
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

338963:PCAR RS02470
gene id: 338963:PCAR_RS02470
uniprot id: Q3A7M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

338963:PCAR RS13815
gene id: 338963:PCAR_RS13815
uniprot id: Q3A1I5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

338963:PCAR RS11535
gene id: 338963:PCAR_RS11535
uniprot id: Q3A2R6
names: Similarity
messages: Belongs to the NifX/NifY family.

338963:PCAR RS03125
gene id: 338963:PCAR_RS03125
uniprot id: Q3A797
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

338963:PCAR RS14565
gene id: 338963:PCAR_RS14565
uniprot id: Q3A144
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

338963:PCAR RS03485
gene id: 338963:PCAR_RS03485
uniprot id: Q3A737
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

338963:PCAR RS01630
gene id: 338963:PCAR_RS01630
uniprot id: Q3A827
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

338963:PCAR RS16700
gene id: 338963:PCAR_RS16700
uniprot id: Q39ZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

338963:PCAR RS07130
gene id: 338963:PCAR_RS07130
uniprot id: Q3A549
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS13545
gene id: 338963:PCAR_RS13545
uniprot id: Q3A1N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS11795
gene id: 338963:PCAR_RS11795
uniprot id: Q3A2L8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS03105
gene id: 338963:PCAR_RS03105
uniprot id: Q3A7A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338963:PCAR RS05580
gene id: 338963:PCAR_RS05580
uniprot id: Q3A602
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

338963:PCAR RS01960
gene id: 338963:PCAR_RS01960
uniprot id: Q3A7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

338963:PCAR RS04145
gene id: 338963:PCAR_RS04145
uniprot id: Q3A6S0
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

338963:PCAR RS00695
gene id: 338963:PCAR_RS00695
uniprot id: Q3A8K2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338963:PCAR RS07480
gene id: 338963:PCAR_RS07480
uniprot id: Q3A4Y2
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

338963:PCAR RS09175
gene id: 338963:PCAR_RS09175
uniprot id: Q3A415
names: Similarity
messages: Belongs to the histone deacetylase family.

338963:PCAR RS02025
gene id: 338963:PCAR_RS02025
uniprot id: Q3A7V6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

338963:PCAR RS04230
gene id: 338963:PCAR_RS04230
uniprot id: Q3A6Q8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

338963:PCAR RS01905
gene id: 338963:PCAR_RS01905
uniprot id: Q3A7X7
names: Similarity
messages: Belongs to the AOR/FOR family.

338963:PCAR RS04315
gene id: 338963:PCAR_RS04315
uniprot id: Q3A6P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

338963:PCAR RS16115
gene id: 338963:PCAR_RS16115
uniprot id: Q3A091
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

338963:PCAR RS07245
gene id: 338963:PCAR_RS07245
uniprot id: Q3A526
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

338963:PCAR RS04435
gene id: 338963:PCAR_RS04435
uniprot id: Q3A6L5
names: Similarity
messages: Belongs to the TrpC family.

338963:PCAR RS15955
gene id: 338963:PCAR_RS15955
uniprot id: Q3A0C2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

338963:PCAR RS04480
gene id: 338963:PCAR_RS04480
uniprot id: Q3A6K6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS07460
gene id: 338963:PCAR_RS07460
uniprot id: Q3A4Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

338963:PCAR RS14985
gene id: 338963:PCAR_RS14985
uniprot id: Q3A0W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

338963:PCAR RS08805
gene id: 338963:PCAR_RS08805
uniprot id: Q3A485
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Membrane

338963:PCAR RS12075
gene id: 338963:PCAR_RS12075
uniprot id: Q3A2G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

338963:PCAR RS16885
gene id: 338963:PCAR_RS16885
uniprot id: Q39ZU8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

338963:PCAR RS08110
gene id: 338963:PCAR_RS08110
uniprot id: Q3A4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS18990
gene id: 338963:PCAR_RS18990
uniprot id: Q3A707
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS04460
gene id: 338963:PCAR_RS04460
uniprot id: Q3A6L0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

338963:PCAR RS04165
gene id: 338963:PCAR_RS04165
uniprot id: Q3A6R6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS02405
gene id: 338963:PCAR_RS02405
uniprot id: Q57390
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

338963:PCAR RS16355
gene id: 338963:PCAR_RS16355
uniprot id: Q3A043
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS05935
gene id: 338963:PCAR_RS05935
uniprot id: Q3A5T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS02675
gene id: 338963:PCAR_RS02675
uniprot id: Q3A7I4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS04000
gene id: 338963:PCAR_RS04000
uniprot id: Q3A6U8
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

338963:PCAR RS01070
gene id: 338963:PCAR_RS01070
uniprot id: Q3A8D0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

338963:PCAR RS14290
gene id: 338963:PCAR_RS14290
uniprot id: Q3A195
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338963:PCAR RS02440
gene id: 338963:PCAR_RS02440
uniprot id: Q3A7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS16300
gene id: 338963:PCAR_RS16300
uniprot id: Q3A054
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07905
gene id: 338963:PCAR_RS07905
uniprot id: Q3A4Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

338963:PCAR RS10310
gene id: 338963:PCAR_RS10310
uniprot id: Q3A3F4
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

338963:PCAR RS04120
gene id: 338963:PCAR_RS04120
uniprot id: Q3A6S5
names: Similarity
messages: Belongs to the peptidase M16 family.

338963:PCAR RS09580
gene id: 338963:PCAR_RS09580
uniprot id: Q3A3U5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338963:PCAR RS01535
gene id: 338963:PCAR_RS01535
uniprot id: Q3A843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Membrane

338963:PCAR RS10260
gene id: 338963:PCAR_RS10260
uniprot id: Q3A3G4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

338963:PCAR RS18985
gene id: 338963:PCAR_RS18985
uniprot id: Q3A742
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

338963:PCAR RS11935
gene id: 338963:PCAR_RS11935
uniprot id: Q3A2J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

338963:PCAR RS08680
gene id: 338963:PCAR_RS08680
uniprot id: Q3A4A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

338963:PCAR RS02700
gene id: 338963:PCAR_RS02700
uniprot id: Q3A7H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

338963:PCAR RS11685
gene id: 338963:PCAR_RS11685
uniprot id: Q3A2P0
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

338963:PCAR RS01845
gene id: 338963:PCAR_RS01845
uniprot id: Q3A7Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

338963:PCAR RS01290
gene id: 338963:PCAR_RS01290
uniprot id: Q3A888
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08415
gene id: 338963:PCAR_RS08415
uniprot id: Q3A4G1
names: Similarity
messages: Belongs to the P(II) protein family.

338963:PCAR RS09750
gene id: 338963:PCAR_RS09750
uniprot id: Q3A3R2
names: Similarity
messages: Belongs to the GSP E family.

338963:PCAR RS00655
gene id: 338963:PCAR_RS00655
uniprot id: Q3A8L0
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

338963:PCAR RS02250
gene id: 338963:PCAR_RS02250
uniprot id: Q3A7R3
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

338963:PCAR RS14280
gene id: 338963:PCAR_RS14280
uniprot id: Q3A197
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338963:PCAR RS12745
gene id: 338963:PCAR_RS12745
uniprot id: Q3A232
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

338963:PCAR RS14660
gene id: 338963:PCAR_RS14660
uniprot id: Q3A126
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS11790
gene id: 338963:PCAR_RS11790
uniprot id: Q3A2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP E family.
messages: Cytoplasm

338963:PCAR RS12365
gene id: 338963:PCAR_RS12365
uniprot id: Q3A2A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

338963:PCAR RS14130
gene id: 338963:PCAR_RS14130
uniprot id: Q3A1C5
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

338963:PCAR RS13755
gene id: 338963:PCAR_RS13755
uniprot id: Q3A1J7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
messages: Membrane

338963:PCAR RS10520
gene id: 338963:PCAR_RS10520
uniprot id: Q3A3B3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS16100
gene id: 338963:PCAR_RS16100
uniprot id: Q3A094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338963:PCAR RS10190
gene id: 338963:PCAR_RS10190
uniprot id: Q3A3H7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

338963:PCAR RS10375
gene id: 338963:PCAR_RS10375
uniprot id: Q3A3E2
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

338963:PCAR RS04005
gene id: 338963:PCAR_RS04005
uniprot id: Q3A6U7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

338963:PCAR RS15360
gene id: 338963:PCAR_RS15360
uniprot id: Q3A0N7
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

338963:PCAR RS09145
gene id: 338963:PCAR_RS09145
uniprot id: Q3A420
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

338963:PCAR RS10330
gene id: 338963:PCAR_RS10330
uniprot id: Q3A3F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

338963:PCAR RS15485
gene id: 338963:PCAR_RS15485
uniprot id: Q3A0L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS18610
gene id: 338963:PCAR_RS18610
uniprot id: Q3A510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS14285
gene id: 338963:PCAR_RS14285
uniprot id: Q3A196
names: Similarity
messages: Belongs to the universal stress protein A family.

338963:PCAR RS04345
gene id: 338963:PCAR_RS04345
uniprot id: Q3A6N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

338963:PCAR RS12080
gene id: 338963:PCAR_RS12080
uniprot id: Q3A2G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

338963:PCAR RS06555
gene id: 338963:PCAR_RS06555
uniprot id: Q3A5F9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

338963:PCAR RS07920
gene id: 338963:PCAR_RS07920
uniprot id: Q3A4Q5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

338963:PCAR RS00630
gene id: 338963:PCAR_RS00630
uniprot id: Q3A8L5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS03750
gene id: 338963:PCAR_RS03750
uniprot id: Q3A8N4
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

338963:PCAR RS11780
gene id: 338963:PCAR_RS11780
uniprot id: Q3A2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338963:PCAR RS04035
gene id: 338963:PCAR_RS04035
uniprot id: Q3A6U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338963:PCAR RS10200
gene id: 338963:PCAR_RS10200
uniprot id: Q3A3H5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS04890
gene id: 338963:PCAR_RS04890
uniprot id: Q3A6D3
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07370
gene id: 338963:PCAR_RS07370
uniprot id: Q3A501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

338963:PCAR RS09455
gene id: 338963:PCAR_RS09455
uniprot id: Q3A3X0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338963:PCAR RS08480
gene id: 338963:PCAR_RS08480
uniprot id: Q3A4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

338963:PCAR RS07320
gene id: 338963:PCAR_RS07320
uniprot id: Q3A511
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

338963:PCAR RS04030
gene id: 338963:PCAR_RS04030
uniprot id: Q3A6U3
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

338963:PCAR RS17630
gene id: 338963:PCAR_RS17630
uniprot id: Q3A795
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338963:PCAR RS09370
gene id: 338963:PCAR_RS09370
uniprot id: Q3A3Y0
names: Similarity
messages: Belongs to the GSP E family.

338963:PCAR RS09440
gene id: 338963:PCAR_RS09440
uniprot id: Q3A3X3
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

338963:PCAR RS10395
gene id: 338963:PCAR_RS10395
uniprot id: Q3A3D8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

338963:PCAR RS11920
gene id: 338963:PCAR_RS11920
uniprot id: Q3A2J3
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

338963:PCAR RS02555
gene id: 338963:PCAR_RS02555
uniprot id: Q3A7K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

338963:PCAR RS11390
gene id: 338963:PCAR_RS11390
uniprot id: Q3A2U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

338963:PCAR RS05440
gene id: 338963:PCAR_RS05440
uniprot id: Q3A630
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

338963:PCAR RS18265
gene id: 338963:PCAR_RS18265
uniprot id: Q3A6N4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

338963:PCAR RS15150
gene id: 338963:PCAR_RS15150
uniprot id: Q3A0S9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

338963:PCAR RS14065
gene id: 338963:PCAR_RS14065
uniprot id: Q3A1D7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

338963:PCAR RS12210
gene id: 338963:PCAR_RS12210
uniprot id: Q3A2D7
names: Similarity
messages: Belongs to the GARS family.

338963:PCAR RS10455
gene id: 338963:PCAR_RS10455
uniprot id: Q3A3C6
names: Similarity
messages: Belongs to the RecJ family.

338963:PCAR RS10695
gene id: 338963:PCAR_RS10695
uniprot id: Q3A378
names: Similarity
messages: Belongs to the sigma-54 factor family.

338963:PCAR RS14415
gene id: 338963:PCAR_RS14415
uniprot id: Q3A174
names: Similarity
messages: Belongs to the CvfB family.

338963:PCAR RS01570
gene id: 338963:PCAR_RS01570
uniprot id: Q3A836
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS08870
gene id: 338963:PCAR_RS08870
uniprot id: Q3A473
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

338963:PCAR RS07125
gene id: 338963:PCAR_RS07125
uniprot id: Q3A550
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

338963:PCAR RS04095
gene id: 338963:PCAR_RS04095
uniprot id: Q3A6T0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS08070
gene id: 338963:PCAR_RS08070
uniprot id: Q3A4M7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

338963:PCAR RS06050
gene id: 338963:PCAR_RS06050
uniprot id: Q3A5R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

338963:PCAR RS05435
gene id: 338963:PCAR_RS05435
uniprot id: Q3A631
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

338963:PCAR RS02220
gene id: 338963:PCAR_RS02220
uniprot id: Q3A7S0
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

338963:PCAR RS06090
gene id: 338963:PCAR_RS06090
uniprot id: Q3A5Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

338963:PCAR RS15015
gene id: 338963:PCAR_RS15015
uniprot id: Q3A0V6
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

338963:PCAR RS13855
gene id: 338963:PCAR_RS13855
uniprot id: Q3A1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

338963:PCAR RS04370
gene id: 338963:PCAR_RS04370
uniprot id: Q3A6M9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

338963:PCAR RS01005
gene id: 338963:PCAR_RS01005
uniprot id: Q3A8E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

338963:PCAR RS02125
gene id: 338963:PCAR_RS02125
uniprot id: Q3A7T7
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

338963:PCAR RS07860
gene id: 338963:PCAR_RS07860
uniprot id: Q3A4R5
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.

338963:PCAR RS13390
gene id: 338963:PCAR_RS13390
uniprot id: Q3A1R5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS12020
gene id: 338963:PCAR_RS12020
uniprot id: Q3A2H5
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

338963:PCAR RS16930
gene id: 338963:PCAR_RS16930
uniprot id: Q39ZT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

338963:PCAR RS17775
gene id: 338963:PCAR_RS17775
uniprot id: Q3A4W5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS04925
gene id: 338963:PCAR_RS04925
uniprot id: Q3A6C6
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

338963:PCAR RS10600
gene id: 338963:PCAR_RS10600
uniprot id: Q3A397
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

338963:PCAR RS10505
gene id: 338963:PCAR_RS10505
uniprot id: Q3A3B6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

338963:PCAR RS06540
gene id: 338963:PCAR_RS06540
uniprot id: Q3A5G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

338963:PCAR RS11035
gene id: 338963:PCAR_RS11035
uniprot id: Q3A313
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

338963:PCAR RS04380
gene id: 338963:PCAR_RS04380
uniprot id: Q3A6M7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

338963:PCAR RS08420
gene id: 338963:PCAR_RS08420
uniprot id: Q3A4G0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

338963:PCAR RS09675
gene id: 338963:PCAR_RS09675
uniprot id: Q3A3S6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338963:PCAR RS16560
gene id: 338963:PCAR_RS16560
uniprot id: Q3A009
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

338963:PCAR RS16640
gene id: 338963:PCAR_RS16640
uniprot id: Q39ZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

338963:PCAR RS10140
gene id: 338963:PCAR_RS10140
uniprot id: Q3A3I7
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

338963:PCAR RS03120
gene id: 338963:PCAR_RS03120
uniprot id: Q3A798
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

338963:PCAR RS09955
gene id: 338963:PCAR_RS09955
uniprot id: Q3A3M4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338963:PCAR RS11555
gene id: 338963:PCAR_RS11555
uniprot id: Q3A2R2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

338963:PCAR RS15075
gene id: 338963:PCAR_RS15075
uniprot id: Q3A0U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

338963:PCAR RS11820
gene id: 338963:PCAR_RS11820
uniprot id: Q3A2L3
names: Similarity
messages: Belongs to the PilY1 family.

338963:PCAR RS03955
gene id: 338963:PCAR_RS03955
uniprot id: Q3A6V7
names: Similarity
messages: Belongs to the LOG family.

338963:PCAR RS05960
gene id: 338963:PCAR_RS05960
uniprot id: Q3A5T0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

338963:PCAR RS14795
gene id: 338963:PCAR_RS14795
uniprot id: Q3A0Z9
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

338963:PCAR RS06825
gene id: 338963:PCAR_RS06825
uniprot id: Q3A5A8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

338963:PCAR RS18040
gene id: 338963:PCAR_RS18040
uniprot id: Q3A1G1
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS16815
gene id: 338963:PCAR_RS16815
uniprot id: Q39ZW0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

338963:PCAR RS02385
gene id: 338963:PCAR_RS02385
uniprot id: Q3A7P2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

338963:PCAR RS16205
gene id: 338963:PCAR_RS16205
uniprot id: Q3A072
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

338963:PCAR RS02690
gene id: 338963:PCAR_RS02690
uniprot id: Q3A7I1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

338963:PCAR RS16275
gene id: 338963:PCAR_RS16275
uniprot id: Q3A059
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS05565
gene id: 338963:PCAR_RS05565
uniprot id: Q3A605
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338963:PCAR RS02425
gene id: 338963:PCAR_RS02425
uniprot id: Q3A7N4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

338963:PCAR RS02075
gene id: 338963:PCAR_RS02075
uniprot id: Q3A7U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS00895
gene id: 338963:PCAR_RS00895
uniprot id: Q3A8G4
names: Similarity
messages: Belongs to the UPF0758 family.

338963:PCAR RS10465
gene id: 338963:PCAR_RS10465
uniprot id: Q3A3C4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

338963:PCAR RS10765
gene id: 338963:PCAR_RS10765
uniprot id: Q3A365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

338963:PCAR RS01425
gene id: 338963:PCAR_RS01425
uniprot id: Q3A864
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

338963:PCAR RS01450
gene id: 338963:PCAR_RS01450
uniprot id: Q3A859
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

338963:PCAR RS01805
gene id: 338963:PCAR_RS01805
uniprot id: Q3A7Z7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

338963:PCAR RS09560
gene id: 338963:PCAR_RS09560
uniprot id: Q3A3U9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS11630
gene id: 338963:PCAR_RS11630
uniprot id: Q3A2P8
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

338963:PCAR RS08555
gene id: 338963:PCAR_RS08555
uniprot id: Q3A4D3
names: Similarity
messages: Belongs to the FemABX family.

338963:PCAR RS17795
gene id: 338963:PCAR_RS17795
uniprot id: Q3A4I7
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS12955
gene id: 338963:PCAR_RS12955
uniprot id: Q3A201
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

338963:PCAR RS08160
gene id: 338963:PCAR_RS08160
uniprot id: Q3A4K9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS12115
gene id: 338963:PCAR_RS12115
uniprot id: Q3A2F6
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS01615
gene id: 338963:PCAR_RS01615
uniprot id: Q3A828
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

338963:PCAR RS13295
gene id: 338963:PCAR_RS13295
uniprot id: Q3A1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

338963:PCAR RS11140
gene id: 338963:PCAR_RS11140
uniprot id: Q3A2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

338963:PCAR RS03070
gene id: 338963:PCAR_RS03070
uniprot id: Q3A7A8
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338963:PCAR RS12700
gene id: 338963:PCAR_RS12700
uniprot id: Q3A241
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

338963:PCAR RS06910
gene id: 338963:PCAR_RS06910
uniprot id: Q3A591
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

338963:PCAR RS09010
gene id: 338963:PCAR_RS09010
uniprot id: Q3A445
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

338963:PCAR RS16845
gene id: 338963:PCAR_RS16845
uniprot id: Q39ZV5
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.
messages: Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).

338963:PCAR RS09295
gene id: 338963:PCAR_RS09295
uniprot id: Q3A3Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

338963:PCAR RS15900
gene id: 338963:PCAR_RS15900
uniprot id: Q3A0D3
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

338963:PCAR RS01875
gene id: 338963:PCAR_RS01875
uniprot id: Q3A7Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

338963:PCAR RS15095
gene id: 338963:PCAR_RS15095
uniprot id: Q3A0U0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338963:PCAR RS06830
gene id: 338963:PCAR_RS06830
uniprot id: Q3A5A7
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

338963:PCAR RS17940
gene id: 338963:PCAR_RS17940
uniprot id: Q3A2F9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS12140
gene id: 338963:PCAR_RS12140
uniprot id: Q3A2F1
names: Similarity
messages: Belongs to the UPF0102 family.

338963:PCAR RS10595
gene id: 338963:PCAR_RS10595
uniprot id: Q3A398
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

338963:PCAR RS05680
gene id: 338963:PCAR_RS05680
uniprot id: Q3A5X8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS06780
gene id: 338963:PCAR_RS06780
uniprot id: Q3A5B7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

338963:PCAR RS03760
gene id: 338963:PCAR_RS03760
uniprot id: Q3A8N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

338963:PCAR RS01055
gene id: 338963:PCAR_RS01055
uniprot id: Q3A8D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS11625
gene id: 338963:PCAR_RS11625
uniprot id: Q3A2P9
names: Similarity
messages: Belongs to the UPF0237 family.

338963:PCAR RS09425
gene id: 338963:PCAR_RS09425
uniprot id: Q3A3X4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

338963:PCAR RS15465
gene id: 338963:PCAR_RS15465
uniprot id: Q3A0L9
names: Similarity
messages: Belongs to the AOR/FOR family.

338963:PCAR RS10605
gene id: 338963:PCAR_RS10605
uniprot id: Q3A396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

338963:PCAR RS04940
gene id: 338963:PCAR_RS04940
uniprot id: Q3A6C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

338963:PCAR RS15290
gene id: 338963:PCAR_RS15290
uniprot id: Q3A0Q1
names: Similarity
messages: Belongs to the VgrG protein family.

338963:PCAR RS08155
gene id: 338963:PCAR_RS08155
uniprot id: Q3A4L0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

338963:PCAR RS04150
gene id: 338963:PCAR_RS04150
uniprot id: Q3A6R9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

338963:PCAR RS08195
gene id: 338963:PCAR_RS08195
uniprot id: Q3A4K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS07655
gene id: 338963:PCAR_RS07655
uniprot id: Q3A4U9
names: Similarity
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

338963:PCAR RS01840
gene id: 338963:PCAR_RS01840
uniprot id: Q3A7Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

338963:PCAR RS10680
gene id: 338963:PCAR_RS10680
uniprot id: Q3A381
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

338963:PCAR RS03505
gene id: 338963:PCAR_RS03505
uniprot id: Q3A733
names: Similarity
messages: Belongs to the disproportionating enzyme family.

338963:PCAR RS10865
gene id: 338963:PCAR_RS10865
uniprot id: Q3A345
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

338963:PCAR RS04420
gene id: 338963:PCAR_RS04420
uniprot id: Q3A6L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

338963:PCAR RS08105
gene id: 338963:PCAR_RS08105
uniprot id: Q3A4M0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

338963:PCAR RS08990
gene id: 338963:PCAR_RS08990
uniprot id: Q3A449
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

338963:PCAR RS08665
gene id: 338963:PCAR_RS08665
uniprot id: Q3A4B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS10185
gene id: 338963:PCAR_RS10185
uniprot id: Q3A3H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

338963:PCAR RS06790
gene id: 338963:PCAR_RS06790
uniprot id: Q3A5B5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

338963:PCAR RS01090
gene id: 338963:PCAR_RS01090
uniprot id: Q3A8C6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

338963:PCAR RS07015
gene id: 338963:PCAR_RS07015
uniprot id: Q3A572
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS14270
gene id: 338963:PCAR_RS14270
uniprot id: Q3A199
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS03500
gene id: 338963:PCAR_RS03500
uniprot id: Q3A734
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

338963:PCAR RS02000
gene id: 338963:PCAR_RS02000
uniprot id: Q3A7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

338963:PCAR RS18140
gene id: 338963:PCAR_RS18140
uniprot id: Q3A0E8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

338963:PCAR RS15480
gene id: 338963:PCAR_RS15480
uniprot id: Q3A0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS03475
gene id: 338963:PCAR_RS03475
uniprot id: Q3A739
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

338963:PCAR RS03665
gene id: 338963:PCAR_RS03665
uniprot id: Q3A709
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

338963:PCAR RS15995
gene id: 338963:PCAR_RS15995
uniprot id: Q3A0B4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338963:PCAR RS09555
gene id: 338963:PCAR_RS09555
uniprot id: Q3A3V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

338963:PCAR RS01485
gene id: 338963:PCAR_RS01485
uniprot id: Q3A852
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

338963:PCAR RS12750
gene id: 338963:PCAR_RS12750
uniprot id: Q3A231
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

338963:PCAR RS01645
gene id: 338963:PCAR_RS01645
uniprot id: Q3A826
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338963:PCAR RS08965
gene id: 338963:PCAR_RS08965
uniprot id: Q3A454
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

338963:PCAR RS14615
gene id: 338963:PCAR_RS14615
uniprot id: Q3A135
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

338963:PCAR RS06665
gene id: 338963:PCAR_RS06665
uniprot id: Q3A5D7
names: Similarity
messages: Belongs to the MotB family.

338963:PCAR RS03110
gene id: 338963:PCAR_RS03110
uniprot id: Q3A7A0
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
messages: Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

338963:PCAR RS14725
gene id: 338963:PCAR_RS14725
uniprot id: Q3A113
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338963:PCAR RS12780
gene id: 338963:PCAR_RS12780
uniprot id: Q3A225
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

338963:PCAR RS04110
gene id: 338963:PCAR_RS04110
uniprot id: Q3A6S7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

338963:PCAR RS14135
gene id: 338963:PCAR_RS14135
uniprot id: Q3A1C4
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

338963:PCAR RS12755
gene id: 338963:PCAR_RS12755
uniprot id: Q3A230
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

338963:PCAR RS11050
gene id: 338963:PCAR_RS11050
uniprot id: Q3A311
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

338963:PCAR RS12260
gene id: 338963:PCAR_RS12260
uniprot id: Q3A2C7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

338963:PCAR RS01865
gene id: 338963:PCAR_RS01865
uniprot id: Q3A7Y5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

338963:PCAR RS09035
gene id: 338963:PCAR_RS09035
uniprot id: Q3A441
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS06515
gene id: 338963:PCAR_RS06515
uniprot id: Q3A5G7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338963:PCAR RS07510
gene id: 338963:PCAR_RS07510
uniprot id: Q3A4X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

338963:PCAR RS03785
gene id: 338963:PCAR_RS03785
uniprot id: Q3A6Z1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS11440
gene id: 338963:PCAR_RS11440
uniprot id: Q3A2T5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS11515
gene id: 338963:PCAR_RS11515
uniprot id: Q3A2S0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS04665
gene id: 338963:PCAR_RS04665
uniprot id: Q3A6H3
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338963:PCAR RS06630
gene id: 338963:PCAR_RS06630
uniprot id: Q3A5E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

338963:PCAR RS05460
gene id: 338963:PCAR_RS05460
uniprot id: Q3A626
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

338963:PCAR RS14760
gene id: 338963:PCAR_RS14760
uniprot id: Q3A106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338963:PCAR RS00570
gene id: 338963:PCAR_RS00570
uniprot id: Q3A8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

338963:PCAR RS12255
gene id: 338963:PCAR_RS12255
uniprot id: Q3A2C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

338963:PCAR RS04260
gene id: 338963:PCAR_RS04260
uniprot id: Q3A6Q2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

338963:PCAR RS10620
gene id: 338963:PCAR_RS10620
uniprot id: Q3A393
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS04455
gene id: 338963:PCAR_RS04455
uniprot id: Q3A6L1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

338963:PCAR RS11350
gene id: 338963:PCAR_RS11350
uniprot id: Q3A2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

338963:PCAR RS11525
gene id: 338963:PCAR_RS11525
uniprot id: Q3A2R8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).
messages: This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.

338963:PCAR RS05845
gene id: 338963:PCAR_RS05845
uniprot id: Q3A5V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

338963:PCAR RS09630
gene id: 338963:PCAR_RS09630
uniprot id: Q3A3T5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

338963:PCAR RS10555
gene id: 338963:PCAR_RS10555
uniprot id: Q3A3A6
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

338963:PCAR RS12060
gene id: 338963:PCAR_RS12060
uniprot id: Q3A2G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

338963:PCAR RS15365
gene id: 338963:PCAR_RS15365
uniprot id: Q3A0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

338963:PCAR RS04670
gene id: 338963:PCAR_RS04670
uniprot id: Q3A6H2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

338963:PCAR RS06545
gene id: 338963:PCAR_RS06545
uniprot id: Q3A5G1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

338963:PCAR RS12055
gene id: 338963:PCAR_RS12055
uniprot id: Q3A2G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

338963:PCAR RS10230
gene id: 338963:PCAR_RS10230
uniprot id: Q3A3H0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338963:PCAR RS03710
gene id: 338963:PCAR_RS03710
uniprot id: Q3A700
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

338963:PCAR RS12635
gene id: 338963:PCAR_RS12635
uniprot id: Q3A253
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

338963:PCAR RS04050
gene id: 338963:PCAR_RS04050
uniprot id: Q3A6T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

338963:PCAR RS16125
gene id: 338963:PCAR_RS16125
uniprot id: Q3A089
names: Similarity
messages: Belongs to the pyruvate kinase family.

338963:PCAR RS14635
gene id: 338963:PCAR_RS14635
uniprot id: Q3A131
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

338963:PCAR RS15165
gene id: 338963:PCAR_RS15165
uniprot id: Q3A0S6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule.

338963:PCAR RS06945
gene id: 338963:PCAR_RS06945
uniprot id: Q3A585
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

338963:PCAR RS01540
gene id: 338963:PCAR_RS01540
uniprot id: Q3A842
names: Similarity
messages: Belongs to the TPP enzyme family.

338963:PCAR RS03705
gene id: 338963:PCAR_RS03705
uniprot id: Q3A701
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338963:PCAR RS04660
gene id: 338963:PCAR_RS04660
uniprot id: Q3A6H4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338963:PCAR RS10550
gene id: 338963:PCAR_RS10550
uniprot id: Q3A3A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

338963:PCAR RS12120
gene id: 338963:PCAR_RS12120
uniprot id: Q3A2F5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

338963:PCAR RS13795
gene id: 338963:PCAR_RS13795
uniprot id: Q3A1I9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS06025
gene id: 338963:PCAR_RS06025
uniprot id: Q3A5R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS14045
gene id: 338963:PCAR_RS14045
uniprot id: Q3A1E1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

338963:PCAR RS05235
gene id: 338963:PCAR_RS05235
uniprot id: Q3A668
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

338963:PCAR RS07295
gene id: 338963:PCAR_RS07295
uniprot id: Q3A516
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

338963:PCAR RS10870
gene id: 338963:PCAR_RS10870
uniprot id: Q3A344
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

338963:PCAR RS02665
gene id: 338963:PCAR_RS02665
uniprot id: Q3A7I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

338963:PCAR RS15870
gene id: 338963:PCAR_RS15870
uniprot id: Q3A0D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

338963:PCAR RS16085
gene id: 338963:PCAR_RS16085
uniprot id: Q3A097
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

338963:PCAR RS07475
gene id: 338963:PCAR_RS07475
uniprot id: Q3A4Y3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS14630
gene id: 338963:PCAR_RS14630
uniprot id: Q3A132
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

338963:PCAR RS11750
gene id: 338963:PCAR_RS11750
uniprot id: Q3A2M7
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07505
gene id: 338963:PCAR_RS07505
uniprot id: Q3A4X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS11080
gene id: 338963:PCAR_RS11080
uniprot id: Q3A305
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS06765
gene id: 338963:PCAR_RS06765
uniprot id: Q3A5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS10735
gene id: 338963:PCAR_RS10735
uniprot id: Q3A370
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

338963:PCAR RS04270
gene id: 338963:PCAR_RS04270
uniprot id: Q3A6Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

338963:PCAR RS09605
gene id: 338963:PCAR_RS09605
uniprot id: Q3A3U0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS03745
gene id: 338963:PCAR_RS03745
uniprot id: Q3A8N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338963:PCAR RS16745
gene id: 338963:PCAR_RS16745
uniprot id: Q39ZX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

338963:PCAR RS08115
gene id: 338963:PCAR_RS08115
uniprot id: Q3A4L8
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

338963:PCAR RS16695
gene id: 338963:PCAR_RS16695
uniprot id: Q39ZY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

338963:PCAR RS15120
gene id: 338963:PCAR_RS15120
uniprot id: Q3A0T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

338963:PCAR RS17805
gene id: 338963:PCAR_RS17805
uniprot id: Q3A4H2
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10840
gene id: 338963:PCAR_RS10840
uniprot id: Q3A350
names: Function
names: Similarity
messages: Belongs to the MoaB/Mog family.
messages: May be involved in the biosynthesis of molybdopterin.

338963:PCAR RS15920
gene id: 338963:PCAR_RS15920
uniprot id: Q3A0C9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

338963:PCAR RS11015
gene id: 338963:PCAR_RS11015
uniprot id: Q3A317
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

338963:PCAR RS09185
gene id: 338963:PCAR_RS09185
uniprot id: Q3A414
names: Similarity
messages: Belongs to the peptidase M1 family.

338963:PCAR RS05175
gene id: 338963:PCAR_RS05175
uniprot id: Q3A680
names: Similarity
messages: Belongs to the GSP E family.

338963:PCAR RS06060
gene id: 338963:PCAR_RS06060
uniprot id: Q3A5R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

338963:PCAR RS12355
gene id: 338963:PCAR_RS12355
uniprot id: Q3A2A8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

338963:PCAR RS12970
gene id: 338963:PCAR_RS12970
uniprot id: Q3A1Z8
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS10725
gene id: 338963:PCAR_RS10725
uniprot id: Q3A372
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

338963:PCAR RS15490
gene id: 338963:PCAR_RS15490
uniprot id: Q3A0L4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

338963:PCAR RS16555
gene id: 338963:PCAR_RS16555
uniprot id: Q3A010
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338963:PCAR RS15910
gene id: 338963:PCAR_RS15910
uniprot id: Q3A0D1
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

338963:PCAR RS13465
gene id: 338963:PCAR_RS13465
uniprot id: Q3A1Q1
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS01935
gene id: 338963:PCAR_RS01935
uniprot id: Q3A7X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

338963:PCAR RS10430
gene id: 338963:PCAR_RS10430
uniprot id: Q3A3D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS11890
gene id: 338963:PCAR_RS11890
uniprot id: Q3A2J9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

338963:PCAR RS06975
gene id: 338963:PCAR_RS06975
uniprot id: Q3A580
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

338963:PCAR RS13710
gene id: 338963:PCAR_RS13710
uniprot id: Q3A1K5
names: Similarity
messages: Belongs to the AOR/FOR family.

338963:PCAR RS01970
gene id: 338963:PCAR_RS01970
uniprot id: Q3A7W4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08760
gene id: 338963:PCAR_RS08760
uniprot id: Q3A493
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

338963:PCAR RS07120
gene id: 338963:PCAR_RS07120
uniprot id: Q3A551
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338963:PCAR RS13560
gene id: 338963:PCAR_RS13560
uniprot id: Q3A1N2
names: Similarity
messages: Belongs to the transglycosylase Slt family.

338963:PCAR RS16310
gene id: 338963:PCAR_RS16310
uniprot id: Q3A052
names: Similarity
messages: Belongs to the universal stress protein A family.

338963:PCAR RS11465
gene id: 338963:PCAR_RS11465
uniprot id: Q3A2T0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.

338963:PCAR RS11445
gene id: 338963:PCAR_RS11445
uniprot id: Q3A2T4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS04275
gene id: 338963:PCAR_RS04275
uniprot id: Q3A6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

338963:PCAR RS16330
gene id: 338963:PCAR_RS16330
uniprot id: Q3A048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS11245
gene id: 338963:PCAR_RS11245
uniprot id: Q3A2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

338963:PCAR RS05550
gene id: 338963:PCAR_RS05550
uniprot id: Q3A608
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

338963:PCAR RS00870
gene id: 338963:PCAR_RS00870
uniprot id: Q3A8G8
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS03945
gene id: 338963:PCAR_RS03945
uniprot id: Q3A6V9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS03830
gene id: 338963:PCAR_RS03830
uniprot id: Q3A6Y2
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS01945
gene id: 338963:PCAR_RS01945
uniprot id: Q3A7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

338963:PCAR RS12065
gene id: 338963:PCAR_RS12065
uniprot id: Q3A2G6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

338963:PCAR RS04575
gene id: 338963:PCAR_RS04575
uniprot id: Q3A6I8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

338963:PCAR RS07255
gene id: 338963:PCAR_RS07255
uniprot id: Q3A524
names: Similarity
messages: Belongs to the YicC/YloC family.

338963:PCAR RS07365
gene id: 338963:PCAR_RS07365
uniprot id: Q3A502
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

338963:PCAR RS02160
gene id: 338963:PCAR_RS02160
uniprot id: Q3A7T1
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

338963:PCAR RS09685
gene id: 338963:PCAR_RS09685
uniprot id: Q3A3S4
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

338963:PCAR RS09885
gene id: 338963:PCAR_RS09885
uniprot id: Q3A3N5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

338963:PCAR RS05985
gene id: 338963:PCAR_RS05985
uniprot id: Q3A5S5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10145
gene id: 338963:PCAR_RS10145
uniprot id: Q3A3I6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

338963:PCAR RS05390
gene id: 338963:PCAR_RS05390
uniprot id: Q3A640
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338963:PCAR RS08200
gene id: 338963:PCAR_RS08200
uniprot id: Q3A4K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS06670
gene id: 338963:PCAR_RS06670
uniprot id: Q3A5D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

338963:PCAR RS10560
gene id: 338963:PCAR_RS10560
uniprot id: Q3A3A5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

338963:PCAR RS03780
gene id: 338963:PCAR_RS03780
uniprot id: Q3A6Z2
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS09545
gene id: 338963:PCAR_RS09545
uniprot id: Q3A3V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

338963:PCAR RS13435
gene id: 338963:PCAR_RS13435
uniprot id: Q3A1Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

338963:PCAR RS03990
gene id: 338963:PCAR_RS03990
uniprot id: Q3A6V0
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS12070
gene id: 338963:PCAR_RS12070
uniprot id: Q3A2G5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS05050
gene id: 338963:PCAR_RS05050
uniprot id: Q3A6A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338963:PCAR RS15810
gene id: 338963:PCAR_RS15810
uniprot id: Q3A0E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

338963:PCAR RS18185
gene id: 338963:PCAR_RS18185
uniprot id: Q39ZZ4
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS14655
gene id: 338963:PCAR_RS14655
uniprot id: Q3A127
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

338963:PCAR RS07885
gene id: 338963:PCAR_RS07885
uniprot id: Q3A4R0
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

338963:PCAR RS07185
gene id: 338963:PCAR_RS07185
uniprot id: Q3A538
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

338963:PCAR RS02755
gene id: 338963:PCAR_RS02755
uniprot id: Q3A7G8
names: Similarity
messages: Belongs to the AlaDH/PNT family.

338963:PCAR RS07280
gene id: 338963:PCAR_RS07280
uniprot id: Q3A519
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

338963:PCAR RS06905
gene id: 338963:PCAR_RS06905
uniprot id: Q3A592
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

338963:PCAR RS02695
gene id: 338963:PCAR_RS02695
uniprot id: Q3A7I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

338963:PCAR RS13190
gene id: 338963:PCAR_RS13190
uniprot id: Q3A1V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

338963:PCAR RS10655
gene id: 338963:PCAR_RS10655
uniprot id: Q3A386
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS06080
gene id: 338963:PCAR_RS06080
uniprot id: Q3A5Q6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

338963:PCAR RS15460
gene id: 338963:PCAR_RS15460
uniprot id: Q3A0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

338963:PCAR RS13400
gene id: 338963:PCAR_RS13400
uniprot id: Q3A1R3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

338963:PCAR RS08135
gene id: 338963:PCAR_RS08135
uniprot id: Q3A4L4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS04390
gene id: 338963:PCAR_RS04390
uniprot id: Q3A6M5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

338963:PCAR RS10975
gene id: 338963:PCAR_RS10975
uniprot id: Q3A325
names: Similarity
messages: Belongs to the citrate synthase family.

338963:PCAR RS08710
gene id: 338963:PCAR_RS08710
uniprot id: Q3A4A3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

338963:PCAR RS15065
gene id: 338963:PCAR_RS15065
uniprot id: Q3A0U6
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS16015
gene id: 338963:PCAR_RS16015
uniprot id: Q3A0B1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

338963:PCAR RS02895
gene id: 338963:PCAR_RS02895
uniprot id: Q3A7E2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

338963:PCAR RS12925
gene id: 338963:PCAR_RS12925
uniprot id: Q3A206
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

338963:PCAR RS13315
gene id: 338963:PCAR_RS13315
uniprot id: Q3A1T0
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

338963:PCAR RS13805
gene id: 338963:PCAR_RS13805
uniprot id: Q3A1I7
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

338963:PCAR RS16215
gene id: 338963:PCAR_RS16215
uniprot id: Q3A070
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS16155
gene id: 338963:PCAR_RS16155
uniprot id: Q3A082
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

338963:PCAR RS04715
gene id: 338963:PCAR_RS04715
uniprot id: Q3A6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

338963:PCAR RS10540
gene id: 338963:PCAR_RS10540
uniprot id: Q3A3A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

338963:PCAR RS04325
gene id: 338963:PCAR_RS04325
uniprot id: Q3A6N9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

338963:PCAR RS08010
gene id: 338963:PCAR_RS08010
uniprot id: Q3A4N8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338963:PCAR RS05305
gene id: 338963:PCAR_RS05305
uniprot id: Q3A655
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

338963:PCAR RS11540
gene id: 338963:PCAR_RS11540
uniprot id: Q3A2R5
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

338963:PCAR RS01985
gene id: 338963:PCAR_RS01985
uniprot id: Q3A7W3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS08595
gene id: 338963:PCAR_RS08595
uniprot id: Q3A4C6
names: Similarity
messages: Belongs to the polysaccharide synthase family.

338963:PCAR RS11885
gene id: 338963:PCAR_RS11885
uniprot id: Q3A2K0
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

338963:PCAR RS03795
gene id: 338963:PCAR_RS03795
uniprot id: Q3A6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

338963:PCAR RS13825
gene id: 338963:PCAR_RS13825
uniprot id: Q3A1I3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

338963:PCAR RS16915
gene id: 338963:PCAR_RS16915
uniprot id: Q39ZU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

338963:PCAR RS11715
gene id: 338963:PCAR_RS11715
uniprot id: Q3A2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

338963:PCAR RS14525
gene id: 338963:PCAR_RS14525
uniprot id: Q3A152
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338963:PCAR RS12110
gene id: 338963:PCAR_RS12110
uniprot id: Q3A2F7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

338963:PCAR RS09415
gene id: 338963:PCAR_RS09415
uniprot id: Q3A3X6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

338963:PCAR RS17945
gene id: 338963:PCAR_RS17945
uniprot id: Q3A2E6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

338963:PCAR RS18940
gene id: 338963:PCAR_RS18940
uniprot id: Q3A8I6
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10290
gene id: 338963:PCAR_RS10290
uniprot id: Q3A3F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

338963:PCAR RS16545
gene id: 338963:PCAR_RS16545
uniprot id: Q3A011
names: Similarity
messages: Belongs to the ALAD family.

338963:PCAR RS17655
gene id: 338963:PCAR_RS17655
uniprot id: Q3A6Z3
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS00750
gene id: 338963:PCAR_RS00750
uniprot id: Q3A8J1
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS13015
gene id: 338963:PCAR_RS13015
uniprot id: Q3A1Y9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

338963:PCAR RS10410
gene id: 338963:PCAR_RS10410
uniprot id: Q3A3D5
names: Similarity
messages: Belongs to the peptidase S49 family.

338963:PCAR RS12465
gene id: 338963:PCAR_RS12465
uniprot id: Q3A286
names: Similarity
messages: Belongs to the SfsA family.

338963:PCAR RS13440
gene id: 338963:PCAR_RS13440
uniprot id: Q3A1Q6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338963:PCAR RS06595
gene id: 338963:PCAR_RS06595
uniprot id: Q3A5F1
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

338963:PCAR RS01820
gene id: 338963:PCAR_RS01820
uniprot id: Q3A7Z4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

338963:PCAR RS10270
gene id: 338963:PCAR_RS10270
uniprot id: Q3A3G2
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS05570
gene id: 338963:PCAR_RS05570
uniprot id: Q3A604
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

338963:PCAR RS04225
gene id: 338963:PCAR_RS04225
uniprot id: Q3A6Q9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

338963:PCAR RS11040
gene id: 338963:PCAR_RS11040
uniprot id: Q3A312
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

338963:PCAR RS08730
gene id: 338963:PCAR_RS08730
uniprot id: Q3A499
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

338963:PCAR RS03855
gene id: 338963:PCAR_RS03855
uniprot id: Q3A6X7
names: Similarity
messages: Belongs to the UPF0047 family.

338963:PCAR RS09830
gene id: 338963:PCAR_RS09830
uniprot id: Q3A3P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

338963:PCAR RS16080
gene id: 338963:PCAR_RS16080
uniprot id: Q3A098
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane

338963:PCAR RS16920
gene id: 338963:PCAR_RS16920
uniprot id: Q39ZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

338963:PCAR RS12895
gene id: 338963:PCAR_RS12895
uniprot id: Q3A212
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

338963:PCAR RS07975
gene id: 338963:PCAR_RS07975
uniprot id: Q3A4P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

338963:PCAR RS10800
gene id: 338963:PCAR_RS10800
uniprot id: Q3A358
names: Similarity
messages: Belongs to the band 7/mec-2 family.

338963:PCAR RS04865
gene id: 338963:PCAR_RS04865
uniprot id: Q3A6D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338963:PCAR RS02360
gene id: 338963:PCAR_RS02360
uniprot id: Q3A7P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

338963:PCAR RS07715
gene id: 338963:PCAR_RS07715
uniprot id: Q3A4T9
names: Similarity
messages: Belongs to the peptidase C40 family.

338963:PCAR RS08905
gene id: 338963:PCAR_RS08905
uniprot id: Q3A466
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338963:PCAR RS01300
gene id: 338963:PCAR_RS01300
uniprot id: Q3A886
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

338963:PCAR RS08750
gene id: 338963:PCAR_RS08750
uniprot id: Q3A495
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

338963:PCAR RS13260
gene id: 338963:PCAR_RS13260
uniprot id: Q3A1U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

338963:PCAR RS14050
gene id: 338963:PCAR_RS14050
uniprot id: Q3A1E0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

338963:PCAR RS12320
gene id: 338963:PCAR_RS12320
uniprot id: Q3A2B5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

338963:PCAR RS09100
gene id: 338963:PCAR_RS09100
uniprot id: Q3A3H2
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338963:PCAR RS10420
gene id: 338963:PCAR_RS10420
uniprot id: Q3A3D3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

338963:PCAR RS00575
gene id: 338963:PCAR_RS00575
uniprot id: Q3A8M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

338963:PCAR RS05555
gene id: 338963:PCAR_RS05555
uniprot id: Q39ZT9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

338963:PCAR RS06325
gene id: 338963:PCAR_RS06325
uniprot id: Q3A5K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Membrane

338963:PCAR RS05540
gene id: 338963:PCAR_RS05540
uniprot id: Q39ZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

338963:PCAR RS07225
gene id: 338963:PCAR_RS07225
uniprot id: Q3A530
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

338963:PCAR RS02830
gene id: 338963:PCAR_RS02830
uniprot id: Q3A7F5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

338963:PCAR RS13230
gene id: 338963:PCAR_RS13230
uniprot id: Q3A1U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

338963:PCAR RS07340
gene id: 338963:PCAR_RS07340
uniprot id: Q3A507
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

338963:PCAR RS01285
gene id: 338963:PCAR_RS01285
uniprot id: Q3A889
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

338963:PCAR RS00680
gene id: 338963:PCAR_RS00680
uniprot id: Q3A8K5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

338963:PCAR RS16535
gene id: 338963:PCAR_RS16535
uniprot id: Q3A013
names: Similarity
messages: Belongs to the peptidase M16 family.

338963:PCAR RS02550
gene id: 338963:PCAR_RS02550
uniprot id: Q3A7L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

338963:PCAR RS03005
gene id: 338963:PCAR_RS03005
uniprot id: Q3A7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

338963:PCAR RS06550
gene id: 338963:PCAR_RS06550
uniprot id: Q3A5G0
names: Similarity
messages: Belongs to the bacterial flagellin family.

338963:PCAR RS14240
gene id: 338963:PCAR_RS14240
uniprot id: Q3A1A4
names: Similarity
messages: Belongs to the MYG1 family.

338963:PCAR RS04280
gene id: 338963:PCAR_RS04280
uniprot id: Q3A6P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

338963:PCAR RS13955
gene id: 338963:PCAR_RS13955
uniprot id: Q3A1F9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338963:PCAR RS08720
gene id: 338963:PCAR_RS08720
uniprot id: Q3A4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

338963:PCAR RS02625
gene id: 338963:PCAR_RS02625
uniprot id: Q3A7J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

338963:PCAR RS09290
gene id: 338963:PCAR_RS09290
uniprot id: Q3A3Z5
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

338963:PCAR RS12105
gene id: 338963:PCAR_RS12105
uniprot id: Q3A2F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

338963:PCAR RS08795
gene id: 338963:PCAR_RS08795
uniprot id: Q3A487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS15675
gene id: 338963:PCAR_RS15675
uniprot id: Q3A0H6
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

338963:PCAR RS07310
gene id: 338963:PCAR_RS07310
uniprot id: Q3A513
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

338963:PCAR RS13225
gene id: 338963:PCAR_RS13225
uniprot id: Q3A1U8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

338963:PCAR RS13860
gene id: 338963:PCAR_RS13860
uniprot id: Q3A1H7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

338963:PCAR RS14430
gene id: 338963:PCAR_RS14430
uniprot id: Q3A171
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338963:PCAR RS06620
gene id: 338963:PCAR_RS06620
uniprot id: Q3A5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

338963:PCAR RS08090
gene id: 338963:PCAR_RS08090
uniprot id: Q3A4M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

338963:PCAR RS04690
gene id: 338963:PCAR_RS04690
uniprot id: Q3A6G9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.
messages: Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.
messages: Monomer and homodimer.

338963:PCAR RS16925
gene id: 338963:PCAR_RS16925
uniprot id: Q39ZU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338963:PCAR RS13790
gene id: 338963:PCAR_RS13790
uniprot id: Q3A1J0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

338963:PCAR RS17780
gene id: 338963:PCAR_RS17780
uniprot id: Q3A4V4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS13675
gene id: 338963:PCAR_RS13675
uniprot id: Q3A1L1
names: Similarity
messages: Belongs to the UPF0166 family.

338963:PCAR RS12625
gene id: 338963:PCAR_RS12625
uniprot id: Q3A255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

338963:PCAR RS02535
gene id: 338963:PCAR_RS02535
uniprot id: Q3A7L2
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS08145
gene id: 338963:PCAR_RS08145
uniprot id: Q3A4L2
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

338963:PCAR RS10940
gene id: 338963:PCAR_RS10940
uniprot id: Q3A331
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

338963:PCAR RS02560
gene id: 338963:PCAR_RS02560
uniprot id: Q3A7K8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

338963:PCAR RS08725
gene id: 338963:PCAR_RS08725
uniprot id: Q3A4A0
names: Similarity
messages: Belongs to the peptidase M16 family.

338963:PCAR RS13145
gene id: 338963:PCAR_RS13145
uniprot id: Q3A1W4
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

338963:PCAR RS10625
gene id: 338963:PCAR_RS10625
uniprot id: Q3A392
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

338963:PCAR RS12225
gene id: 338963:PCAR_RS12225
uniprot id: Q3A2D4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

338963:PCAR RS06195
gene id: 338963:PCAR_RS06195
uniprot id: Q3A5N3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

338963:PCAR RS14155
gene id: 338963:PCAR_RS14155
uniprot id: Q3A1C0
names: Similarity
messages: Belongs to the glutamate synthase family.

338963:PCAR RS08690
gene id: 338963:PCAR_RS08690
uniprot id: Q3A4A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

338963:PCAR RS04400
gene id: 338963:PCAR_RS04400
uniprot id: Q3A6M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

338963:PCAR RS08535
gene id: 338963:PCAR_RS08535
uniprot id: Q3A4D7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

338963:PCAR RS02185
gene id: 338963:PCAR_RS02185
uniprot id: Q3A7S6
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

338963:PCAR RS04405
gene id: 338963:PCAR_RS04405
uniprot id: Q3A6M1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

338963:PCAR RS10645
gene id: 338963:PCAR_RS10645
uniprot id: Q3A388
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

338963:PCAR RS18270
gene id: 338963:PCAR_RS18270
uniprot id: Q3A6M4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

338963:PCAR RS13140
gene id: 338963:PCAR_RS13140
uniprot id: Q3A1W5
names: Similarity
messages: Belongs to the CinA family.

338963:PCAR RS13410
gene id: 338963:PCAR_RS13410
uniprot id: Q3A1R2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

338963:PCAR RS01655
gene id: 338963:PCAR_RS01655
uniprot id: Q3A824
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338963:PCAR RS15100
gene id: 338963:PCAR_RS15100
uniprot id: Q3A0T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

338963:PCAR RS09235
gene id: 338963:PCAR_RS09235
uniprot id: Q3A405
names: Similarity
messages: Belongs to the peptidase S41A family.

338963:PCAR RS09575
gene id: 338963:PCAR_RS09575
uniprot id: Q3A3U6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

338963:PCAR RS12560
gene id: 338963:PCAR_RS12560
uniprot id: Q3A268
names: Similarity
messages: Belongs to the Lgt family.

338963:PCAR RS06180
gene id: 338963:PCAR_RS06180
uniprot id: Q3A5N6
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

338963:PCAR RS09345
gene id: 338963:PCAR_RS09345
uniprot id: Q3A3Y5
names: Similarity
messages: Belongs to the bacterial secretin family.

338963:PCAR RS04635
gene id: 338963:PCAR_RS04635
uniprot id: Q3A6H9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS08085
gene id: 338963:PCAR_RS08085
uniprot id: Q3A4M4
names: Similarity
messages: Belongs to the fabD family.

338963:PCAR RS12870
gene id: 338963:PCAR_RS12870
uniprot id: Q3A217
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

338963:PCAR RS04310
gene id: 338963:PCAR_RS04310
uniprot id: Q3A6P2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

338963:PCAR RS03115
gene id: 338963:PCAR_RS03115
uniprot id: Q3A799
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobS family.
messages: Cell inner membrane
messages: Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
messages: Membrane

338963:PCAR RS14510
gene id: 338963:PCAR_RS14510
uniprot id: Q3A155
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338963:PCAR RS11250
gene id: 338963:PCAR_RS11250
uniprot id: Q3A2X2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

338963:PCAR RS08165
gene id: 338963:PCAR_RS08165
uniprot id: Q3A4K8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

338963:PCAR RS02715
gene id: 338963:PCAR_RS02715
uniprot id: Q3A7H6
names: Similarity
messages: Belongs to the DprA/Smf family.

338963:PCAR RS08930
gene id: 338963:PCAR_RS08930
uniprot id: Q3A461
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

338963:PCAR RS09935
gene id: 338963:PCAR_RS09935
uniprot id: Q3A3M7
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

338963:PCAR RS06115
gene id: 338963:PCAR_RS06115
uniprot id: Q3A5P9
names: Similarity
messages: Belongs to the TlyA family.

338963:PCAR RS06980
gene id: 338963:PCAR_RS06980
uniprot id: Q3A579
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

338963:PCAR RS02565
gene id: 338963:PCAR_RS02565
uniprot id: Q3A7K7
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

338963:PCAR RS06660
gene id: 338963:PCAR_RS06660
uniprot id: Q3A5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

338963:PCAR RS06880
gene id: 338963:PCAR_RS06880
uniprot id: Q3A597
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS09135
gene id: 338963:PCAR_RS09135
uniprot id: Q3A422
names: Similarity
messages: Belongs to the creatininase superfamily.

338963:PCAR RS13215
gene id: 338963:PCAR_RS13215
uniprot id: Q3A1V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

338963:PCAR RS05220
gene id: 338963:PCAR_RS05220
uniprot id: Q3A670
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

338963:PCAR RS01785
gene id: 338963:PCAR_RS01785
uniprot id: Q3A801
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

338963:PCAR RS04790
gene id: 338963:PCAR_RS04790
uniprot id: Q3A6F3
names: Similarity
messages: Belongs to the DNA polymerase type-A family.

338963:PCAR RS13930
gene id: 338963:PCAR_RS13930
uniprot id: Q3A1G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

338963:PCAR RS08190
gene id: 338963:PCAR_RS08190
uniprot id: Q3A4K3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

338963:PCAR RS10250
gene id: 338963:PCAR_RS10250
uniprot id: Q3A3G6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

338963:PCAR RS15530
gene id: 338963:PCAR_RS15530
uniprot id: Q3A0K6
names: Similarity
messages: Belongs to the cytochrome c-552 family.

338963:PCAR RS10660
gene id: 338963:PCAR_RS10660
uniprot id: Q3A385
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS15960
gene id: 338963:PCAR_RS15960
uniprot id: Q3A0C1
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

338963:PCAR RS00565
gene id: 338963:PCAR_RS00565
uniprot id: Q3A8M8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

338963:PCAR RS02165
gene id: 338963:PCAR_RS02165
uniprot id: Q3A7T0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS10720
gene id: 338963:PCAR_RS10720
uniprot id: Q3A373
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

338963:PCAR RS04090
gene id: 338963:PCAR_RS04090
uniprot id: Q3A6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338963:PCAR RS05800
gene id: 338963:PCAR_RS05800
uniprot id: Q3A5W0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

338963:PCAR RS00810
gene id: 338963:PCAR_RS00810
uniprot id: Q3A8H9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
messages: Homodimer.

338963:PCAR RS08780
gene id: 338963:PCAR_RS08780
uniprot id: Q3A489
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

338963:PCAR RS14140
gene id: 338963:PCAR_RS14140
uniprot id: Q3A1C3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

338963:PCAR RS12985
gene id: 338963:PCAR_RS12985
uniprot id: Q3A1Z5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10525
gene id: 338963:PCAR_RS10525
uniprot id: Q3A3B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS08285
gene id: 338963:PCAR_RS08285
uniprot id: Q3A4I4
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

338963:PCAR RS10920
gene id: 338963:PCAR_RS10920
uniprot id: Q3A334
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338963:PCAR RS08220
gene id: 338963:PCAR_RS08220
uniprot id: Q3A4J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS17980
gene id: 338963:PCAR_RS17980
uniprot id: Q3A265
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS02710
gene id: 338963:PCAR_RS02710
uniprot id: Q3A7H7
names: Similarity
messages: Belongs to the Smg family.

338963:PCAR RS10000
gene id: 338963:PCAR_RS10000
uniprot id: Q3A3L2
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

338963:PCAR RS13600
gene id: 338963:PCAR_RS13600
uniprot id: Q3A1M4
names: Similarity
messages: Belongs to the UPF0166 family.

338963:PCAR RS12200
gene id: 338963:PCAR_RS12200
uniprot id: Q3A2D9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08715
gene id: 338963:PCAR_RS08715
uniprot id: Q3A4A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

338963:PCAR RS07080
gene id: 338963:PCAR_RS07080
uniprot id: Q3A559
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07135
gene id: 338963:PCAR_RS07135
uniprot id: Q3A548
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

338963:PCAR RS10905
gene id: 338963:PCAR_RS10905
uniprot id: Q3A337
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS01080
gene id: 338963:PCAR_RS01080
uniprot id: Q3A8C8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

338963:PCAR RS00670
gene id: 338963:PCAR_RS00670
uniprot id: Q3A8K7
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS14610
gene id: 338963:PCAR_RS14610
uniprot id: Q3A136
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

338963:PCAR RS12960
gene id: 338963:PCAR_RS12960
uniprot id: Q3A200
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

338963:PCAR RS00605
gene id: 338963:PCAR_RS00605
uniprot id: Q3A8M0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

338963:PCAR RS05805
gene id: 338963:PCAR_RS05805
uniprot id: Q3A5V9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

338963:PCAR RS05815
gene id: 338963:PCAR_RS05815
uniprot id: Q3A5V7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

338963:PCAR RS12680
gene id: 338963:PCAR_RS12680
uniprot id: Q3A245
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

338963:PCAR RS04730
gene id: 338963:PCAR_RS04730
uniprot id: Q3A6G2
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

338963:PCAR RS12000
gene id: 338963:PCAR_RS12000
uniprot id: Q3A2H9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS08225
gene id: 338963:PCAR_RS08225
uniprot id: Q3A4J6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

338963:PCAR RS10610
gene id: 338963:PCAR_RS10610
uniprot id: Q3A395
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

338963:PCAR RS10325
gene id: 338963:PCAR_RS10325
uniprot id: Q3A3F2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

338963:PCAR RS12085
gene id: 338963:PCAR_RS12085
uniprot id: Q3A2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

338963:PCAR RS04395
gene id: 338963:PCAR_RS04395
uniprot id: Q3A6M3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

338963:PCAR RS01685
gene id: 338963:PCAR_RS01685
uniprot id: Q3A818
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338963:PCAR RS07970
gene id: 338963:PCAR_RS07970
uniprot id: Q3A4P5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

338963:PCAR RS15175
gene id: 338963:PCAR_RS15175
uniprot id: Q3A0S4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

338963:PCAR RS14495
gene id: 338963:PCAR_RS14495
uniprot id: Q3A158
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

338963:PCAR RS01510
gene id: 338963:PCAR_RS01510
uniprot id: Q3A847
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS10480
gene id: 338963:PCAR_RS10480
uniprot id: Q3A3C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

338963:PCAR RS03740
gene id: 338963:PCAR_RS03740
uniprot id: Q3A8N6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

338963:PCAR RS12475
gene id: 338963:PCAR_RS12475
uniprot id: Q3A284
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338963:PCAR RS13155
gene id: 338963:PCAR_RS13155
uniprot id: Q3A1W2
names: Similarity
messages: Belongs to the GSP E family.

338963:PCAR RS06615
gene id: 338963:PCAR_RS06615
uniprot id: Q3A5E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

338963:PCAR RS12270
gene id: 338963:PCAR_RS12270
uniprot id: Q3A2C5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS16185
gene id: 338963:PCAR_RS16185
uniprot id: Q3A076
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

338963:PCAR RS03730
gene id: 338963:PCAR_RS03730
uniprot id: Q3A6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

338963:PCAR RS08370
gene id: 338963:PCAR_RS08370
uniprot id: Q3A4G9
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

338963:PCAR RS05545
gene id: 338963:PCAR_RS05545
uniprot id: Q39ZT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

338963:PCAR RS15520
gene id: 338963:PCAR_RS15520
uniprot id: Q3A0K8
names: Similarity
names: Subunit
messages: Belongs to the RNase H family.
messages: Monomer.

338963:PCAR RS12485
gene id: 338963:PCAR_RS12485
uniprot id: Q3A282
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

338963:PCAR RS08940
gene id: 338963:PCAR_RS08940
uniprot id: Q3A459
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338963:PCAR RS16710
gene id: 338963:PCAR_RS16710
uniprot id: Q39ZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338963:PCAR RS14185
gene id: 338963:PCAR_RS14185
uniprot id: Q3A1B5
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338963:PCAR RS00705
gene id: 338963:PCAR_RS00705
uniprot id: Q3A8K0
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS15740
gene id: 338963:PCAR_RS15740
uniprot id: Q3A0G3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS12145
gene id: 338963:PCAR_RS12145
uniprot id: Q3A2F0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

338963:PCAR RS07955
gene id: 338963:PCAR_RS07955
uniprot id: Q3A4P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

338963:PCAR RS01810
gene id: 338963:PCAR_RS01810
uniprot id: Q3A7Z6
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

338963:PCAR RS12855
gene id: 338963:PCAR_RS12855
uniprot id: Q3A220
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS12360
gene id: 338963:PCAR_RS12360
uniprot id: Q3A2A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

338963:PCAR RS11805
gene id: 338963:PCAR_RS11805
uniprot id: Q3A2L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

338963:PCAR RS02880
gene id: 338963:PCAR_RS02880
uniprot id: Q3A7E5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS08120
gene id: 338963:PCAR_RS08120
uniprot id: Q3A4L7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

338963:PCAR RS11870
gene id: 338963:PCAR_RS11870
uniprot id: Q3A2K3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

338963:PCAR RS16705
gene id: 338963:PCAR_RS16705
uniprot id: Q39ZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

338963:PCAR RS04205
gene id: 338963:PCAR_RS04205
uniprot id: Q3A6R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

338963:PCAR RS03865
gene id: 338963:PCAR_RS03865
uniprot id: Q3A6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

338963:PCAR RS14070
gene id: 338963:PCAR_RS14070
uniprot id: Q3A1D6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

338963:PCAR RS15985
gene id: 338963:PCAR_RS15985
uniprot id: Q3A0B6
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

338963:PCAR RS06885
gene id: 338963:PCAR_RS06885
uniprot id: Q3A596
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

338963:PCAR RS02840
gene id: 338963:PCAR_RS02840
uniprot id: Q3A7F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

338963:PCAR RS17745
gene id: 338963:PCAR_RS17745
uniprot id: Q3A5E1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

338963:PCAR RS13300
gene id: 338963:PCAR_RS13300
uniprot id: Q3A1T3
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

338963:PCAR RS05605
gene id: 338963:PCAR_RS05605
uniprot id: Q3A5Z8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

338963:PCAR RS11480
gene id: 338963:PCAR_RS11480
uniprot id: Q3A2S7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338963:PCAR RS03185
gene id: 338963:PCAR_RS03185
uniprot id: Q3A785
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS03980
gene id: 338963:PCAR_RS03980
uniprot id: Q3A6V2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

338963:PCAR RS08030
gene id: 338963:PCAR_RS08030
uniprot id: Q3A4N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

338963:PCAR RS11925
gene id: 338963:PCAR_RS11925
uniprot id: Q3A2J2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338963:PCAR RS11010
gene id: 338963:PCAR_RS11010
uniprot id: Q3A318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

338963:PCAR RS04295
gene id: 338963:PCAR_RS04295
uniprot id: Q3A6P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

338963:PCAR RS10005
gene id: 338963:PCAR_RS10005
uniprot id: Q3A3L1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS12175
gene id: 338963:PCAR_RS12175
uniprot id: Q3A2E4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

338963:PCAR RS01680
gene id: 338963:PCAR_RS01680
uniprot id: Q3A819
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338963:PCAR RS09810
gene id: 338963:PCAR_RS09810
uniprot id: Q3A3Q0
names: Similarity
messages: Belongs to the heat shock protein 90 family.

338963:PCAR RS03090
gene id: 338963:PCAR_RS03090
uniprot id: Q3A7A4
names: Similarity
messages: Belongs to the CobH/CbiC family.

338963:PCAR RS06270
gene id: 338963:PCAR_RS06270
uniprot id: Q3A5L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS09965
gene id: 338963:PCAR_RS09965
uniprot id: Q3A3M2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

338963:PCAR RS11175
gene id: 338963:PCAR_RS11175
uniprot id: Q3A2Y7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

338963:PCAR RS15585
gene id: 338963:PCAR_RS15585
uniprot id: Q3A0J5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS02515
gene id: 338963:PCAR_RS02515
uniprot id: Q3A7L6
names: Similarity
messages: Belongs to the DEAD box helicase family.

338963:PCAR RS07425
gene id: 338963:PCAR_RS07425
uniprot id: Q3A4Z0
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

338963:PCAR RS01580
gene id: 338963:PCAR_RS01580
uniprot id: Q3A834
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

338963:PCAR RS06185
gene id: 338963:PCAR_RS06185
uniprot id: Q3A5N5
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

338963:PCAR RS12015
gene id: 338963:PCAR_RS12015
uniprot id: Q3A2H6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS16120
gene id: 338963:PCAR_RS16120
uniprot id: Q3A090
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

338963:PCAR RS16175
gene id: 338963:PCAR_RS16175
uniprot id: Q3A078
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

338963:PCAR RS06585
gene id: 338963:PCAR_RS06585
uniprot id: Q3A5F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

338963:PCAR RS03540
gene id: 338963:PCAR_RS03540
uniprot id: Q3A726
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS10300
gene id: 338963:PCAR_RS10300
uniprot id: Q3A3F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

338963:PCAR RS09325
gene id: 338963:PCAR_RS09325
uniprot id: Q3A3Y8
names: Similarity
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.

338963:PCAR RS10580
gene id: 338963:PCAR_RS10580
uniprot id: Q3A3A1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS07665
gene id: 338963:PCAR_RS07665
uniprot id: Q0C6M9
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

338963:PCAR RS11800
gene id: 338963:PCAR_RS11800
uniprot id: Q3A2L7
names: Similarity
messages: Belongs to the ribF family.

338963:PCAR RS09645
gene id: 338963:PCAR_RS09645
uniprot id: Q3A3T2
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

338963:PCAR RS11740
gene id: 338963:PCAR_RS11740
uniprot id: Q3A2M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

338963:PCAR RS09265
gene id: 338963:PCAR_RS09265
uniprot id: Q3A400
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

338963:PCAR RS05705
gene id: 338963:PCAR_RS05705
uniprot id: Q3A5X3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

338963:PCAR RS04250
gene id: 338963:PCAR_RS04250
uniprot id: Q3A6Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338963:PCAR RS05710
gene id: 338963:PCAR_RS05710
uniprot id: Q3A5X2
names: Similarity
messages: Belongs to the UPF0166 family.

338963:PCAR RS13485
gene id: 338963:PCAR_RS13485
uniprot id: Q3A1P7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

338963:PCAR RS13395
gene id: 338963:PCAR_RS13395
uniprot id: Q3A1R4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

338963:PCAR RS05055
gene id: 338963:PCAR_RS05055
uniprot id: Q3A6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338963:PCAR RS12150
gene id: 338963:PCAR_RS12150
uniprot id: Q3A2E9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

338963:PCAR RS03480
gene id: 338963:PCAR_RS03480
uniprot id: Q3A738
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS17645
gene id: 338963:PCAR_RS17645
uniprot id: Q3A720
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS05180
gene id: 338963:PCAR_RS05180
uniprot id: Q3A679
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS00580
gene id: 338963:PCAR_RS00580
uniprot id: Q3A8M5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

338963:PCAR RS03495
gene id: 338963:PCAR_RS03495
uniprot id: Q3A735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

338963:PCAR RS02760
gene id: 338963:PCAR_RS02760
uniprot id: Q3A7G7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

338963:PCAR RS07500
gene id: 338963:PCAR_RS07500
uniprot id: Q3A4X7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

338963:PCAR RS01545
gene id: 338963:PCAR_RS01545
uniprot id: Q3A841
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS14580
gene id: 338963:PCAR_RS14580
uniprot id: Q3A142
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

338963:PCAR RS14860
gene id: 338963:PCAR_RS14860
uniprot id: Q3A0Y6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

338963:PCAR RS10475
gene id: 338963:PCAR_RS10475
uniprot id: Q3A3C2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

338963:PCAR RS04450
gene id: 338963:PCAR_RS04450
uniprot id: Q3A6L2
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

338963:PCAR RS03970
gene id: 338963:PCAR_RS03970
uniprot id: Q3A6V4
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

338963:PCAR RS02935
gene id: 338963:PCAR_RS02935
uniprot id: Q3A7D4
names: Similarity
messages: Belongs to the MlaA family.

338963:PCAR RS05990
gene id: 338963:PCAR_RS05990
uniprot id: Q3A5S4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

338963:PCAR RS14605
gene id: 338963:PCAR_RS14605
uniprot id: Q3A137
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

338963:PCAR RS15090
gene id: 338963:PCAR_RS15090
uniprot id: Q3A0U1
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS05995
gene id: 338963:PCAR_RS05995
uniprot id: Q3A5S3
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

338963:PCAR RS02235
gene id: 338963:PCAR_RS02235
uniprot id: Q3A7R6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS16600
gene id: 338963:PCAR_RS16600
uniprot id: Q3A001
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

338963:PCAR RS04240
gene id: 338963:PCAR_RS04240
uniprot id: Q3A6Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

338963:PCAR RS14055
gene id: 338963:PCAR_RS14055
uniprot id: Q3A1D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

338963:PCAR RS13110
gene id: 338963:PCAR_RS13110
uniprot id: Q3A1X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS09870
gene id: 338963:PCAR_RS09870
uniprot id: Q3A3N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shikimate kinase family.
messages: Cytoplasm

338963:PCAR RS02265
gene id: 338963:PCAR_RS02265
uniprot id: Q3A7R0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

338963:PCAR RS16595
gene id: 338963:PCAR_RS16595
uniprot id: Q3A002
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS00815
gene id: 338963:PCAR_RS00815
uniprot id: Q3A8H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.

338963:PCAR RS14275
gene id: 338963:PCAR_RS14275
uniprot id: Q3A198
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

338963:PCAR RS12740
gene id: 338963:PCAR_RS12740
uniprot id: Q3A233
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

338963:PCAR RS08425
gene id: 338963:PCAR_RS08425
uniprot id: Q3A4F9
names: Similarity
messages: Belongs to the threonine synthase family.

338963:PCAR RS13160
gene id: 338963:PCAR_RS13160
uniprot id: Q3A1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

338963:PCAR RS15510
gene id: 338963:PCAR_RS15510
uniprot id: Q3A0L0
names: Similarity
messages: Belongs to the UPF0270 family.

338963:PCAR RS01675
gene id: 338963:PCAR_RS01675
uniprot id: Q3A820
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

338963:PCAR RS03690
gene id: 338963:PCAR_RS03690
uniprot id: Q3A704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS12040
gene id: 338963:PCAR_RS12040
uniprot id: Q3A2H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

338963:PCAR RS00790
gene id: 338963:PCAR_RS00790
uniprot id: Q3A8I3
names: Similarity
messages: Belongs to the peptidase C1 family.

338963:PCAR RS04290
gene id: 338963:PCAR_RS04290
uniprot id: Q3A6P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

338963:PCAR RS09565
gene id: 338963:PCAR_RS09565
uniprot id: Q3A3U8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338963:PCAR RS11955
gene id: 338963:PCAR_RS11955
uniprot id: Q3A2I7
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS10795
gene id: 338963:PCAR_RS10795
uniprot id: Q3A359
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

338963:PCAR RS00900
gene id: 338963:PCAR_RS00900
uniprot id: Q3A8G3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS12800
gene id: 338963:PCAR_RS12800
uniprot id: Q3A221
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the desulfoferrodoxin family.
messages: Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via four histidines and one cysteine residue.
messages: Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via 4 cysteine residues.
messages: Catalysis occurs at center II. Fe(2+) ion of center II is the electron donor and is converted to the Fe(3+) form during the reaction (By similarity).
messages: Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity (By similarity).
messages: Homodimer.
messages: Is organized in two protein domains. The N-terminal domain has a fold similar to that of desulforedoxin and contains a mononuclear Fe(3+) ion, center I. The second domain contains a different mononuclear iron center, center II, with a Fe(2+) ion (By similarity).

338963:PCAR RS13240
gene id: 338963:PCAR_RS13240
uniprot id: Q3A1U5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
messages: Homodimer.
messages: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.

338963:PCAR RS02920
gene id: 338963:PCAR_RS02920
uniprot id: Q3A7D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

338963:PCAR RS09195
gene id: 338963:PCAR_RS09195
uniprot id: Q3A412
names: Similarity
messages: Belongs to the MEMO1 family.

338963:PCAR RS06420
gene id: 338963:PCAR_RS06420
uniprot id: Q3A5I7
names: Similarity
messages: Belongs to the TPP enzyme family.

338963:PCAR RS07270
gene id: 338963:PCAR_RS07270
uniprot id: Q3A521
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

338963:PCAR RS05730
gene id: 338963:PCAR_RS05730
uniprot id: Q3A5W9
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

338963:PCAR RS09140
gene id: 338963:PCAR_RS09140
uniprot id: Q3A421
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS00595
gene id: 338963:PCAR_RS00595
uniprot id: Q3A8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

338963:PCAR RS09005
gene id: 338963:PCAR_RS09005
uniprot id: Q3A446
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

338963:PCAR RS14125
gene id: 338963:PCAR_RS14125
uniprot id: Q3A1C6
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

338963:PCAR RS12910
gene id: 338963:PCAR_RS12910
uniprot id: Q3A209
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

338963:PCAR RS10805
gene id: 338963:PCAR_RS10805
uniprot id: Q3A357
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS06385
gene id: 338963:PCAR_RS06385
uniprot id: Q3A5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

338963:PCAR RS03835
gene id: 338963:PCAR_RS03835
uniprot id: Q3A6Y1
names: Similarity
messages: Belongs to the UPF0235 family.

338963:PCAR RS07535
gene id: 338963:PCAR_RS07535
uniprot id: Q3A4X1
names: Similarity
messages: Belongs to the UPF0751 family.

338963:PCAR RS10425
gene id: 338963:PCAR_RS10425
uniprot id: Q3A3D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

338963:PCAR RS01075
gene id: 338963:PCAR_RS01075
uniprot id: Q3A8C9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS02825
gene id: 338963:PCAR_RS02825
uniprot id: Q3A7F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS16980
gene id: 338963:PCAR_RS16980
uniprot id: Q39ZS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

338963:PCAR RS07435
gene id: 338963:PCAR_RS07435
uniprot id: Q3A4Y8
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

338963:PCAR RS13165
gene id: 338963:PCAR_RS13165
uniprot id: Q3A1W0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

338963:PCAR RS05165
gene id: 338963:PCAR_RS05165
uniprot id: Q3A682
names: Similarity
messages: Belongs to the bacterial secretin family.

338963:PCAR RS07845
gene id: 338963:PCAR_RS07845
uniprot id: Q3A4R8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

338963:PCAR RS08910
gene id: 338963:PCAR_RS08910
uniprot id: Q3A465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

338963:PCAR RS12235
gene id: 338963:PCAR_RS12235
uniprot id: Q3A2D2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

338963:PCAR RS13740
gene id: 338963:PCAR_RS13740
uniprot id: Q3A1K0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

338963:PCAR RS07685
gene id: 338963:PCAR_RS07685
uniprot id: J9UJL9
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS16935
gene id: 338963:PCAR_RS16935
uniprot id: Q39ZT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

338963:PCAR RS14500
gene id: 338963:PCAR_RS14500
uniprot id: Q3A157
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

338963:PCAR RS15215
gene id: 338963:PCAR_RS15215
uniprot id: Q3A0R6
names: Subcellular Location Annotation
messages: Cytoplasm

338963:PCAR RS04905
gene id: 338963:PCAR_RS04905
uniprot id: Q3A6D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS02685
gene id: 338963:PCAR_RS02685
uniprot id: Q3A7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

338963:PCAR RS04745
gene id: 338963:PCAR_RS04745
uniprot id: Q3A6F9
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

338963:PCAR RS01915
gene id: 338963:PCAR_RS01915
uniprot id: Q3A7X5
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

338963:PCAR RS12205
gene id: 338963:PCAR_RS12205
uniprot id: Q3A2D8
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

338963:PCAR RS09000
gene id: 338963:PCAR_RS09000
uniprot id: Q3A447
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

338963:PCAR RS08985
gene id: 338963:PCAR_RS08985
uniprot id: Q3A450
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

338963:PCAR RS13200
gene id: 338963:PCAR_RS13200
uniprot id: Q3A1V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

338963:PCAR RS09155
gene id: 338963:PCAR_RS09155
uniprot id: Q3A418
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

338963:PCAR RS03215
gene id: 338963:PCAR_RS03215
uniprot id: Q3A779
names: Similarity
messages: Belongs to the GSP E family.

338963:PCAR RS12460
gene id: 338963:PCAR_RS12460
uniprot id: Q3A287
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

338963:PCAR RS04300
gene id: 338963:PCAR_RS04300
uniprot id: Q3A6P4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

338963:PCAR RS10115
gene id: 338963:PCAR_RS10115
uniprot id: Q3A3J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

338963:PCAR RS01030
gene id: 338963:PCAR_RS01030
uniprot id: Q3A8D7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

338963:PCAR RS05445
gene id: 338963:PCAR_RS05445
uniprot id: Q3A629
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

338963:PCAR RS13380
gene id: 338963:PCAR_RS13380
uniprot id: Q3A1R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338963:PCAR RS08980
gene id: 338963:PCAR_RS08980
uniprot id: Q3A451
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS01660
gene id: 338963:PCAR_RS01660
uniprot id: Q3A823
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

338963:PCAR RS18010
gene id: 338963:PCAR_RS18010
uniprot id: Q3A1X3
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS11025
gene id: 338963:PCAR_RS11025
uniprot id: Q3A315
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

338963:PCAR RS08445
gene id: 338963:PCAR_RS08445
uniprot id: Q3A4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338963:PCAR RS06795
gene id: 338963:PCAR_RS06795
uniprot id: Q3A5B4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

338963:PCAR RS10730
gene id: 338963:PCAR_RS10730
uniprot id: Q3A371
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

338963:PCAR RS15865
gene id: 338963:PCAR_RS15865
uniprot id: Q3A0D9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS09840
gene id: 338963:PCAR_RS09840
uniprot id: Q3A3P4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

338963:PCAR RS00635
gene id: 338963:PCAR_RS00635
uniprot id: Q3A8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.

338963:PCAR RS06590
gene id: 338963:PCAR_RS06590
uniprot id: Q3A5F2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

338963:PCAR RS17690
gene id: 338963:PCAR_RS17690
uniprot id: Q3A6A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

338963:PCAR RS08975
gene id: 338963:PCAR_RS08975
uniprot id: Q3A452
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

338963:PCAR RS13780
gene id: 338963:PCAR_RS13780
uniprot id: Q3A1J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS07095
gene id: 338963:PCAR_RS07095
uniprot id: Q3A556
names: Similarity
messages: Belongs to the Skp family.

338963:PCAR RS12050
gene id: 338963:PCAR_RS12050
uniprot id: Q3A2G9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

338963:PCAR RS08460
gene id: 338963:PCAR_RS08460
uniprot id: Q3A4F2
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS13575
gene id: 338963:PCAR_RS13575
uniprot id: Q3A1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

338963:PCAR RS11895
gene id: 338963:PCAR_RS11895
uniprot id: Q3A2J8
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

338963:PCAR RS13075
gene id: 338963:PCAR_RS13075
uniprot id: Q3A1X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338963:PCAR RS16105
gene id: 338963:PCAR_RS16105
uniprot id: Q3A093
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

338963:PCAR RS08015
gene id: 338963:PCAR_RS08015
uniprot id: Q3A4N7
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

338963:PCAR RS11615
gene id: 338963:PCAR_RS11615
uniprot id: Q3A2Q0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.

338963:PCAR RS14265
gene id: 338963:PCAR_RS14265
uniprot id: Q3A1A0
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS04430
gene id: 338963:PCAR_RS04430
uniprot id: Q3A6L6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

338963:PCAR RS07275
gene id: 338963:PCAR_RS07275
uniprot id: Q3A520
names: Similarity
messages: Belongs to the RutC family.

338963:PCAR RS09760
gene id: 338963:PCAR_RS09760
uniprot id: Q3A3R0
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS02270
gene id: 338963:PCAR_RS02270
uniprot id: Q3A7Q9
names: Subunit
messages: Homodimer.

338963:PCAR RS15560
gene id: 338963:PCAR_RS15560
uniprot id: Q3A0K0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

338963:PCAR RS16565
gene id: 338963:PCAR_RS16565
uniprot id: Q3A008
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

338963:PCAR RS04875
gene id: 338963:PCAR_RS04875
uniprot id: Q3A6D6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338963:PCAR RS06965
gene id: 338963:PCAR_RS06965
uniprot id: Q3A582
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

338963:PCAR RS01950
gene id: 338963:PCAR_RS01950
uniprot id: Q3A7W8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

338963:PCAR RS15445
gene id: 338963:PCAR_RS15445
uniprot id: Q3A0M2
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

338963:PCAR RS14335
gene id: 338963:PCAR_RS14335
uniprot id: Q3A187
names: Similarity
messages: Belongs to the UPF0178 family.

338963:PCAR RS06315
gene id: 338963:PCAR_RS06315
uniprot id: Q3A5K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS00725
gene id: 338963:PCAR_RS00725
uniprot id: Q3A8J6
names: Similarity
messages: Belongs to the UPF0234 family.

338963:PCAR RS14815
gene id: 338963:PCAR_RS14815
uniprot id: Q3A0Z5
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

338963:PCAR RS03055
gene id: 338963:PCAR_RS03055
uniprot id: Q3A7B1
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

338963:PCAR RS13005
gene id: 338963:PCAR_RS13005
uniprot id: Q3A1Z1
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS16965
gene id: 338963:PCAR_RS16965
uniprot id: Q39ZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

338963:PCAR RS09130
gene id: 338963:PCAR_RS09130
uniprot id: Q3A423
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

338963:PCAR RS08675
gene id: 338963:PCAR_RS08675
uniprot id: Q3A4B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

338963:PCAR RS04445
gene id: 338963:PCAR_RS04445
uniprot id: Q3A6L3
names: Similarity
messages: Belongs to the DEAD box helicase family.

338963:PCAR RS13735
gene id: 338963:PCAR_RS13735
uniprot id: Q3A1K1
names: Caution
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS18055
gene id: 338963:PCAR_RS18055
uniprot id: Q3A1B2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

338963:PCAR RS02275
gene id: 338963:PCAR_RS02275
uniprot id: Q3A7Q8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

338963:PCAR RS06655
gene id: 338963:PCAR_RS06655
uniprot id: Q3A5D9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

338963:PCAR RS02490
gene id: 338963:PCAR_RS02490
uniprot id: Q3A7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

338963:PCAR RS12160
gene id: 338963:PCAR_RS12160
uniprot id: Q3A2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

338963:PCAR RS08310
gene id: 338963:PCAR_RS08310
uniprot id: Q3A4H9
names: Similarity
messages: Belongs to the glutamate synthase family.

338963:PCAR RS06105
gene id: 338963:PCAR_RS06105
uniprot id: Q3A5Q1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS01975
gene id: 338963:PCAR_RS01975
uniprot id: Q39ZS5
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS04220
gene id: 338963:PCAR_RS04220
uniprot id: Q3A6R0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

338963:PCAR RS08000
gene id: 338963:PCAR_RS08000
uniprot id: Q3A4P0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

338963:PCAR RS15035
gene id: 338963:PCAR_RS15035
uniprot id: Q3A0V2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

338963:PCAR RS11130
gene id: 338963:PCAR_RS11130
uniprot id: Q3A2Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

338963:PCAR RS01295
gene id: 338963:PCAR_RS01295
uniprot id: Q3A887
names: Similarity
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.

338963:PCAR RS02215
gene id: 338963:PCAR_RS02215
uniprot id: Q3A7S1
names: Function
names: Similarity
messages: Belongs to the NifD/NifK/NifE/NifN family.
messages: This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).

338963:PCAR RS16190
gene id: 338963:PCAR_RS16190
uniprot id: Q3A075
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

338963:PCAR RS09220
gene id: 338963:PCAR_RS09220
uniprot id: Q3A408
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

338963:PCAR RS15160
gene id: 338963:PCAR_RS15160
uniprot id: Q3A0S7
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

338963:PCAR RS09410
gene id: 338963:PCAR_RS09410
uniprot id: Q3A3X7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

338963:PCAR RS06065
gene id: 338963:PCAR_RS06065
uniprot id: Q3A5Q9
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

338963:PCAR RS04285
gene id: 338963:PCAR_RS04285
uniprot id: Q3A6P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

338963:PCAR RS04330
gene id: 338963:PCAR_RS04330
uniprot id: Q3A6N8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

338963:PCAR RS14035
gene id: 338963:PCAR_RS14035
uniprot id: Q3A1E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

338963:PCAR RS04265
gene id: 338963:PCAR_RS04265
uniprot id: Q3A6Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

338963:PCAR RS06070
gene id: 338963:PCAR_RS06070
uniprot id: Q3A5Q8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS07915
gene id: 338963:PCAR_RS07915
uniprot id: Q3A4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS12665
gene id: 338963:PCAR_RS12665
uniprot id: Q3A248
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphopentomutase family.
messages: Binds 1 or 2 manganese ions.
messages: Cytoplasm
messages: Phosphotransfer between the C1 and C5 carbon atoms of pentose.

338963:PCAR RS11995
gene id: 338963:PCAR_RS11995
uniprot id: Q3A2I0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.

338963:PCAR RS06565
gene id: 338963:PCAR_RS06565
uniprot id: Q3A5F7
names: Similarity
messages: Belongs to the FlgM family.

338963:PCAR RS11360
gene id: 338963:PCAR_RS11360
uniprot id: Q3A2V1
names: Similarity
messages: Belongs to the histone deacetylase family.

338963:PCAR RS05110
gene id: 338963:PCAR_RS05110
uniprot id: Q3A692
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

338963:PCAR RS08095
gene id: 338963:PCAR_RS08095
uniprot id: Q3A4M2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

338963:PCAR RS08100
gene id: 338963:PCAR_RS08100
uniprot id: Q3A4M1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

338963:PCAR RS10240
gene id: 338963:PCAR_RS10240
uniprot id: Q3A3G8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

338963:PCAR RS03065
gene id: 338963:PCAR_RS03065
uniprot id: Q3A7A9
names: Function
names: Similarity
messages: Belongs to the CbiD family.
messages: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.

338963:PCAR RS02305
gene id: 338963:PCAR_RS02305
uniprot id: Q3A7Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

338963:PCAR RS03985
gene id: 338963:PCAR_RS03985
uniprot id: Q3A6V1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

338963:PCAR RS04880
gene id: 338963:PCAR_RS04880
uniprot id: Q3A6D5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS10955
gene id: 338963:PCAR_RS10955
uniprot id: Q3A328
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

338963:PCAR RS04375
gene id: 338963:PCAR_RS04375
uniprot id: Q3A6M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

338963:PCAR RS03245
gene id: 338963:PCAR_RS03245
uniprot id: Q3A773
names: Similarity
messages: Belongs to the ArsC family.

338963:PCAR RS12125
gene id: 338963:PCAR_RS12125
uniprot id: Q3A2F4
names: Similarity
messages: Belongs to the acylphosphatase family.

338963:PCAR RS02465
gene id: 338963:PCAR_RS02465
uniprot id: Q3A7M6
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

338963:PCAR RS05780
gene id: 338963:PCAR_RS05780
uniprot id: Q3A5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

338963:PCAR RS11410
gene id: 338963:PCAR_RS11410
uniprot id: Q3A2U1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

338963:PCAR RS13885
gene id: 338963:PCAR_RS13885
uniprot id: Q3A1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

338963:PCAR RS08485
gene id: 338963:PCAR_RS08485
uniprot id: Q3A4E7
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

338963:PCAR RS04210
gene id: 338963:PCAR_RS04210
uniprot id: Q3A6R1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

338963:PCAR RS05000
gene id: 338963:PCAR_RS05000
uniprot id: Q3A6B3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

338963:PCAR RS14640
gene id: 338963:PCAR_RS14640
uniprot id: Q3A130
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

338963:PCAR RS13180
gene id: 338963:PCAR_RS13180
uniprot id: Q3A1V7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

338963:PCAR RS09680
gene id: 338963:PCAR_RS09680
uniprot id: Q3A3S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

338963:PCAR RS00970
gene id: 338963:PCAR_RS00970
uniprot id: Q3A8E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

338963:PCAR RS15135
gene id: 338963:PCAR_RS15135
uniprot id: Q3A0T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS03975
gene id: 338963:PCAR_RS03975
uniprot id: Q3A6V3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

338963:PCAR RS16840
gene id: 338963:PCAR_RS16840
uniprot id: Q39ZV6
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

338963:PCAR RS13150
gene id: 338963:PCAR_RS13150
uniprot id: Q3A1W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

338963:PCAR RS07265
gene id: 338963:PCAR_RS07265
uniprot id: Q3A522
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

338963:PCAR RS01380
gene id: 338963:PCAR_RS01380
uniprot id: Q3A870
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS00735
gene id: 338963:PCAR_RS00735
uniprot id: Q3A8J4
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

338963:PCAR RS09860
gene id: 338963:PCAR_RS09860
uniprot id: Q3A3P0
names: Similarity
messages: Belongs to the MlaA family.

338963:PCAR RS06625
gene id: 338963:PCAR_RS06625
uniprot id: Q3A5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

338963:PCAR RS04235
gene id: 338963:PCAR_RS04235
uniprot id: Q3A6Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

338963:PCAR RS00975
gene id: 338963:PCAR_RS00975
uniprot id: Q3A8E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

338963:PCAR RS09640
gene id: 338963:PCAR_RS09640
uniprot id: Q3A3T3
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

338963:PCAR RS06390
gene id: 338963:PCAR_RS06390
uniprot id: Q3A5J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

338963:PCAR RS13130
gene id: 338963:PCAR_RS13130
uniprot id: Q3A1W7
names: Similarity
messages: Belongs to the LarC family.

338963:PCAR RS13235
gene id: 338963:PCAR_RS13235
uniprot id: Q3A1U6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

338963:PCAR RS16955
gene id: 338963:PCAR_RS16955
uniprot id: Q39ZT4
names: Similarity
messages: Belongs to the ParB family.

338963:PCAR RS02080
gene id: 338963:PCAR_RS02080
uniprot id: Q3A7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

338963:PCAR RS02955
gene id: 338963:PCAR_RS02955
uniprot id: Q3A7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS02370
gene id: 338963:PCAR_RS02370
uniprot id: Q3A7P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

338963:PCAR RS02580
gene id: 338963:PCAR_RS02580
uniprot id: Q3A7K4
names: Subunit
messages: Heterodimer of a large and a small subunit.

338963:PCAR RS00805
gene id: 338963:PCAR_RS00805
uniprot id: Q3A8I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

338963:PCAR RS10690
gene id: 338963:PCAR_RS10690
uniprot id: Q3A379
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

338963:PCAR RS03895
gene id: 338963:PCAR_RS03895
uniprot id: Q3A6W9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

338963:PCAR RS07145
gene id: 338963:PCAR_RS07145
uniprot id: Q3A546
names: Similarity
messages: Belongs to the UPF0434 family.

338963:PCAR RS14995
gene id: 338963:PCAR_RS14995
uniprot id: Q3A0W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

338963:PCAR RS01465
gene id: 338963:PCAR_RS01465
uniprot id: Q3A856
names: Similarity
messages: Belongs to the peptidase S1C family.

338963:PCAR RS04540
gene id: 338963:PCAR_RS04540
uniprot id: Q3A6J5
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

338963:PCAR RS05930
gene id: 338963:PCAR_RS05930
uniprot id: Q3A5T6
names: Similarity
messages: Belongs to the P(II) protein family.

338963:PCAR RS02510
gene id: 338963:PCAR_RS02510
uniprot id: Q3A7L7
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS05925
gene id: 338963:PCAR_RS05925
uniprot id: Q3A5T7
names: Similarity
messages: Belongs to the peptidase S16 family.

338963:PCAR RS00765
gene id: 338963:PCAR_RS00765
uniprot id: Q3A8I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

338963:PCAR RS11705
gene id: 338963:PCAR_RS11705
uniprot id: Q3A2N6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

338963:PCAR RS13070
gene id: 338963:PCAR_RS13070
uniprot id: Q3A1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338963:PCAR RS10925
gene id: 338963:PCAR_RS10925
uniprot id: Q3A333
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

338963:PCAR RS06370
gene id: 338963:PCAR_RS06370
uniprot id: Q3A5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

338963:PCAR RS14085
gene id: 338963:PCAR_RS14085
uniprot id: Q3A1D3
names: Cofactor
names: Similarity
messages: Belongs to the PHP family.
messages: Binds 3 Zn(2+) ions per subunit.

338963:PCAR RS13185
gene id: 338963:PCAR_RS13185
uniprot id: Q3A1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

338963:PCAR RS14060
gene id: 338963:PCAR_RS14060
uniprot id: Q3A1D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS01595
gene id: 338963:PCAR_RS01595
uniprot id: Q3A831
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

338963:PCAR RS07260
gene id: 338963:PCAR_RS07260
uniprot id: Q3A523
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

338963:PCAR RS16945
gene id: 338963:PCAR_RS16945
uniprot id: Q39ZT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

338963:PCAR RS10830
gene id: 338963:PCAR_RS10830
uniprot id: Q3A352
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

338963:PCAR RS13195
gene id: 338963:PCAR_RS13195
uniprot id: Q3A1V4
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

338963:PCAR RS04560
gene id: 338963:PCAR_RS04560
uniprot id: Q3A6J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

338963:PCAR RS04040
gene id: 338963:PCAR_RS04040
uniprot id: Q3A6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

338963:PCAR RS04595
gene id: 338963:PCAR_RS04595
uniprot id: Q3A6I4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

338963:PCAR RS11880
gene id: 338963:PCAR_RS11880
uniprot id: Q3A2K1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

338963:PCAR RS16715
gene id: 338963:PCAR_RS16715
uniprot id: Q39ZX8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

338963:PCAR RS13040
gene id: 338963:PCAR_RS13040
uniprot id: Q3A1Y4
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

338963:PCAR RS04655
gene id: 338963:PCAR_RS04655
uniprot id: Q3A6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

338963:PCAR RS10415
gene id: 338963:PCAR_RS10415
uniprot id: Q3A3D4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.

338963:PCAR RS06700
gene id: 338963:PCAR_RS06700
uniprot id: Q3A5D3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.

338963:PCAR RS10615
gene id: 338963:PCAR_RS10615
uniprot id: Q3A394
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS16220
gene id: 338963:PCAR_RS16220
uniprot id: Q3A069
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

338963:PCAR RS16305
gene id: 338963:PCAR_RS16305
uniprot id: Q3A053
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

338963:PCAR RS05045
gene id: 338963:PCAR_RS05045
uniprot id: Q3A6A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

338963:PCAR RS09420
gene id: 338963:PCAR_RS09420
uniprot id: Q3A3X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

338963:PCAR RS05270
gene id: 338963:PCAR_RS05270
uniprot id: Q3A662
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS07105
gene id: 338963:PCAR_RS07105
uniprot id: Q3A554
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

338963:PCAR RS11145
gene id: 338963:PCAR_RS11145
uniprot id: Q3A2Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS11915
gene id: 338963:PCAR_RS11915
uniprot id: Q3A2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shikimate kinase family.
messages: Cytoplasm

338963:PCAR RS02795
gene id: 338963:PCAR_RS02795
uniprot id: Q3A7G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

338963:PCAR RS12045
gene id: 338963:PCAR_RS12045
uniprot id: Q3A2H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

338963:PCAR RS03470
gene id: 338963:PCAR_RS03470
uniprot id: Q3A740
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

338963:PCAR RS05010
gene id: 338963:PCAR_RS05010
uniprot id: Q3A6B2
names: Subcellular Location Annotation
messages: Membrane

338963:PCAR RS01965
gene id: 338963:PCAR_RS01965
uniprot id: Q3A7W5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

338963:PCAR RS13820
gene id: 338963:PCAR_RS13820
uniprot id: Q3A1I4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

338963:PCAR RS05855
gene id: 338963:PCAR_RS05855
uniprot id: Q3A5U9
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

338963:PCAR RS13475
gene id: 338963:PCAR_RS13475
uniprot id: Q3A1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

338963:PCAR RS04740
gene id: 338963:PCAR_RS04740
uniprot id: Q3A6G0
names: Similarity
messages: Belongs to the SecB family.

338963:PCAR RS04245
gene id: 338963:PCAR_RS04245
uniprot id: Q3A6Q5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

338963:PCAR RS10545
gene id: 338963:PCAR_RS10545
uniprot id: Q3A3A8
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

338963:PCAR RS10770
gene id: 338963:PCAR_RS10770
uniprot id: Q3A364
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

338963:PCAR RS07005
gene id: 338963:PCAR_RS07005
uniprot id: Q3A574
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

338963:PCAR RS10575
gene id: 338963:PCAR_RS10575
uniprot id: Q3A3A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

338963:PCAR RS08430
gene id: 338963:PCAR_RS08430
uniprot id: Q3A4F8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

338963:PCAR RS09190
gene id: 338963:PCAR_RS09190
uniprot id: Q3A413
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

338963:PCAR RS14040
gene id: 338963:PCAR_RS14040
uniprot id: Q3A1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

338963:PCAR RS01860
gene id: 338963:PCAR_RS01860
uniprot id: Q3A7Y6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

338963:PCAR RS07660
gene id: 338963:PCAR_RS07660
uniprot id: Q3A4U8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

338963:PCAR RS11380
gene id: 338963:PCAR_RS11380
uniprot id: Q3A2U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Probably functions as a manganese efflux pump.

338963:PCAR RS09275
gene id: 338963:PCAR_RS09275
uniprot id: Q3A3Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

338963:PCAR RS13610
gene id: 338963:PCAR_RS13610
uniprot id: Q3A1M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

338963:PCAR RS05830
gene id: 338963:PCAR_RS05830
uniprot id: Q3A5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

338963:PCAR RS16895
gene id: 338963:PCAR_RS16895
uniprot id: Q39ZU6
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

338963:PCAR RS09300
gene id: 338963:PCAR_RS09300
uniprot id: Q3A3Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

338963:PCAR RS07020
gene id: 338963:PCAR_RS07020
uniprot id: Q3A571
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.