335541:SWOL RS07665
gene id: 335541:SWOL_RS07665
uniprot id: Q0AWX0
names: Similarity
messages: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.

335541:SWOL RS09440
gene id: 335541:SWOL_RS09440
uniprot id: Q0AVX9
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335541:SWOL RS10695
gene id: 335541:SWOL_RS10695
uniprot id: Q0AV93
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

335541:SWOL RS10070
gene id: 335541:SWOL_RS10070
uniprot id: Q0AVK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

335541:SWOL RS11990
gene id: 335541:SWOL_RS11990
uniprot id: Q0AUJ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

335541:SWOL RS11975
gene id: 335541:SWOL_RS11975
uniprot id: Q0AUK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

335541:SWOL RS02515
gene id: 335541:SWOL_RS02515
uniprot id: Q0AZM3
names: Similarity
messages: Belongs to the type IA topoisomerase family.

335541:SWOL RS09450
gene id: 335541:SWOL_RS09450
uniprot id: Q0AVX7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335541:SWOL RS03990
gene id: 335541:SWOL_RS03990
uniprot id: Q0AYU3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335541:SWOL RS12270
gene id: 335541:SWOL_RS12270
uniprot id: Q0AUE9
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

335541:SWOL RS08840
gene id: 335541:SWOL_RS08840
uniprot id: Q0AW95
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

335541:SWOL RS06350
gene id: 335541:SWOL_RS06350
uniprot id: Q0AXK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335541:SWOL RS01610
gene id: 335541:SWOL_RS01610
uniprot id: Q0B046
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS01580
gene id: 335541:SWOL_RS01580
uniprot id: Q0B052
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

335541:SWOL RS02840
gene id: 335541:SWOL_RS02840
uniprot id: Q0AZG1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

335541:SWOL RS11955
gene id: 335541:SWOL_RS11955
uniprot id: Q0AUK6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

335541:SWOL RS13240
gene id: 335541:SWOL_RS13240
uniprot id: Q0ATV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

335541:SWOL RS04475
gene id: 335541:SWOL_RS04475
uniprot id: Q0AYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

335541:SWOL RS05910
gene id: 335541:SWOL_RS05910
uniprot id: Q0AXU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

335541:SWOL RS01360
gene id: 335541:SWOL_RS01360
uniprot id: Q0B094
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

335541:SWOL RS04330
gene id: 335541:SWOL_RS04330
uniprot id: Q0AYM8
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

335541:SWOL RS09615
gene id: 335541:SWOL_RS09615
uniprot id: Q0AVU6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

335541:SWOL RS01255
gene id: 335541:SWOL_RS01255
uniprot id: Q0B0B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

335541:SWOL RS01310
gene id: 335541:SWOL_RS01310
uniprot id: Q0B0A2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

335541:SWOL RS09200
gene id: 335541:SWOL_RS09200
uniprot id: Q0AW29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

335541:SWOL RS12095
gene id: 335541:SWOL_RS12095
uniprot id: Q0AUH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

335541:SWOL RS09545
gene id: 335541:SWOL_RS09545
uniprot id: Q0AVW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

335541:SWOL RS03945
gene id: 335541:SWOL_RS03945
uniprot id: Q0AYV2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.

335541:SWOL RS10815
gene id: 335541:SWOL_RS10815
uniprot id: Q0AV72
names: Similarity
messages: Belongs to the UPF0251 family.

335541:SWOL RS10225
gene id: 335541:SWOL_RS10225
uniprot id: Q0AVI0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

335541:SWOL RS07485
gene id: 335541:SWOL_RS07485
uniprot id: Q0AWZ9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS08215
gene id: 335541:SWOL_RS08215
uniprot id: Q0AWL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

335541:SWOL RS08580
gene id: 335541:SWOL_RS08580
uniprot id: Q0AWE5
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

335541:SWOL RS04620
gene id: 335541:SWOL_RS04620
uniprot id: Q0AYH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

335541:SWOL RS10185
gene id: 335541:SWOL_RS10185
uniprot id: Q0AVI6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS03135
gene id: 335541:SWOL_RS03135
uniprot id: Q0AZA6
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

335541:SWOL RS12040
gene id: 335541:SWOL_RS12040
uniprot id: Q0AUI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

335541:SWOL RS12215
gene id: 335541:SWOL_RS12215
uniprot id: Q0AUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MrnC RNase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.

335541:SWOL RS00055
gene id: 335541:SWOL_RS00055
uniprot id: Q0B0Y6
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

335541:SWOL RS12035
gene id: 335541:SWOL_RS12035
uniprot id: Q0AUJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

335541:SWOL RS01835
gene id: 335541:SWOL_RS01835
uniprot id: Q0B006
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

335541:SWOL RS06880
gene id: 335541:SWOL_RS06880
uniprot id: Q0AXB7
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

335541:SWOL RS08980
gene id: 335541:SWOL_RS08980
uniprot id: Q0AW67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04355
gene id: 335541:SWOL_RS04355
uniprot id: Q0AYM3
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS06590
gene id: 335541:SWOL_RS06590
uniprot id: Q0AXG3
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS09030
gene id: 335541:SWOL_RS09030
uniprot id: Q0AW62
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335541:SWOL RS00555
gene id: 335541:SWOL_RS00555
uniprot id: Q0B0P9
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

335541:SWOL RS00965
gene id: 335541:SWOL_RS00965
uniprot id: Q0B0H0
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS05120
gene id: 335541:SWOL_RS05120
uniprot id: Q0AY82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

335541:SWOL RS06625
gene id: 335541:SWOL_RS06625
uniprot id: Q0AUU4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

335541:SWOL RS12225
gene id: 335541:SWOL_RS12225
uniprot id: Q0AUF8
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

335541:SWOL RS09990
gene id: 335541:SWOL_RS09990
uniprot id: Q0AVM4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Cytoplasm
messages: Highly expressed during syntrophic growth with butyrate (at protein level) (PubMed:19648244, PubMed:23468890). Seems to be constitutively expressed (PubMed:23468890).
messages: Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Catalyzes the oxidation of butanoyl-CoA to crotonyl-CoA. Probably passes the electrons released by this reaction on to electron-transfer flavoproteins (EtfAB) to finally generate hydrogen and/or formate.

335541:SWOL RS05925
gene id: 335541:SWOL_RS05925
uniprot id: Q0AXT8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

335541:SWOL RS09375
gene id: 335541:SWOL_RS09375
uniprot id: Q0AVZ3
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

335541:SWOL RS05645
gene id: 335541:SWOL_RS05645
uniprot id: Q0AXY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

335541:SWOL RS13380
gene id: 335541:SWOL_RS13380
uniprot id: Q0B0J0
names: Similarity
messages: Belongs to the peptidase S8 family.

335541:SWOL RS08535
gene id: 335541:SWOL_RS08535
uniprot id: Q0AWF4
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

335541:SWOL RS03355
gene id: 335541:SWOL_RS03355
uniprot id: Q0AZ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

335541:SWOL RS05760
gene id: 335541:SWOL_RS05760
uniprot id: Q0AXW9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

335541:SWOL RS04460
gene id: 335541:SWOL_RS04460
uniprot id: Q0AYK2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.

335541:SWOL RS04205
gene id: 335541:SWOL_RS04205
uniprot id: Q0AYQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

335541:SWOL RS03690
gene id: 335541:SWOL_RS03690
uniprot id: Q0AZ00
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS12395
gene id: 335541:SWOL_RS12395
uniprot id: Q0AUC4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

335541:SWOL RS12160
gene id: 335541:SWOL_RS12160
uniprot id: Q0AUG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

335541:SWOL RS09335
gene id: 335541:SWOL_RS09335
uniprot id: Q0AW01
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

335541:SWOL RS01285
gene id: 335541:SWOL_RS01285
uniprot id: Q0B0A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.

335541:SWOL RS04870
gene id: 335541:SWOL_RS04870
uniprot id: Q0AYD0
names: Similarity
messages: Belongs to the UPF0235 family.

335541:SWOL RS01370
gene id: 335541:SWOL_RS01370
uniprot id: Q0B092
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

335541:SWOL RS01930
gene id: 335541:SWOL_RS01930
uniprot id: Q0AZY7
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

335541:SWOL RS08435
gene id: 335541:SWOL_RS08435
uniprot id: Q0AWH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS12830
gene id: 335541:SWOL_RS12830
uniprot id: Q0AU38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS11935
gene id: 335541:SWOL_RS11935
uniprot id: Q0AUL0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

335541:SWOL RS10060
gene id: 335541:SWOL_RS10060
uniprot id: Q0AVL0
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS01365
gene id: 335541:SWOL_RS01365
uniprot id: Q0B093
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

335541:SWOL RS10620
gene id: 335541:SWOL_RS10620
uniprot id: Q0AVA8
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Cytoplasm
messages: Expressed during syntrophic growth with butyrate (at protein level) (PubMed:19648244, PubMed:23468890). Seems to be constitutively expressed (PubMed:23468890).
messages: Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Catalyzes the oxidation of butanoyl-CoA to crotonyl-CoA. Probably passes the electrons released by this reaction on to electron-transfer flavoproteins (EtfAB) to finally generate hydrogen and/or formate.

335541:SWOL RS03720
gene id: 335541:SWOL_RS03720
uniprot id: Q0AYZ5
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

335541:SWOL RS07685
gene id: 335541:SWOL_RS07685
uniprot id: Q0AWW7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS07365
gene id: 335541:SWOL_RS07365
uniprot id: Q0AX23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

335541:SWOL RS05140
gene id: 335541:SWOL_RS05140
uniprot id: Q0AY78
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

335541:SWOL RS10985
gene id: 335541:SWOL_RS10985
uniprot id: Q0AV38
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

335541:SWOL RS06215
gene id: 335541:SWOL_RS06215
uniprot id: Q0AXN6
names: Similarity
messages: Belongs to the SAICAR synthetase family.

335541:SWOL RS02100
gene id: 335541:SWOL_RS02100
uniprot id: Q0AZV4
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

335541:SWOL RS04280
gene id: 335541:SWOL_RS04280
uniprot id: Q0AYN7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

335541:SWOL RS06055
gene id: 335541:SWOL_RS06055
uniprot id: Q0AXR4
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

335541:SWOL RS09880
gene id: 335541:SWOL_RS09880
uniprot id: Q0AVP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

335541:SWOL RS10000
gene id: 335541:SWOL_RS10000
uniprot id: Q0AVM2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: Cytoplasm
messages: Highly expressed during syntrophic growth with butyrate (at protein level). Seems to be constitutively expressed.
messages: Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the oxidation of 3-hydroxybutyryl-CoA to acetoacetyl-CoA.

335541:SWOL RS00460
gene id: 335541:SWOL_RS00460
uniprot id: Q0B0R9
names: Similarity
messages: Belongs to the GerABKA family.

335541:SWOL RS06850
gene id: 335541:SWOL_RS06850
uniprot id: Q0AXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

335541:SWOL RS06335
gene id: 335541:SWOL_RS06335
uniprot id: Q0AXL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

335541:SWOL RS04600
gene id: 335541:SWOL_RS04600
uniprot id: Q0AYH5
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS11855
gene id: 335541:SWOL_RS11855
uniprot id: Q0AUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

335541:SWOL RS07690
gene id: 335541:SWOL_RS07690
uniprot id: Q0AWW6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335541:SWOL RS13290
gene id: 335541:SWOL_RS13290
uniprot id: Q0ATU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

335541:SWOL RS09235
gene id: 335541:SWOL_RS09235
uniprot id: Q0AW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

335541:SWOL RS07420
gene id: 335541:SWOL_RS07420
uniprot id: Q0AX12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

335541:SWOL RS11945
gene id: 335541:SWOL_RS11945
uniprot id: Q0AUK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

335541:SWOL RS04940
gene id: 335541:SWOL_RS04940
uniprot id: Q0AYB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS04350
gene id: 335541:SWOL_RS04350
uniprot id: Q0AYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

335541:SWOL RS00580
gene id: 335541:SWOL_RS00580
uniprot id: Q0B0P4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

335541:SWOL RS01885
gene id: 335541:SWOL_RS01885
uniprot id: Q0AZZ6
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

335541:SWOL RS01320
gene id: 335541:SWOL_RS01320
uniprot id: Q0B0A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

335541:SWOL RS05580
gene id: 335541:SWOL_RS05580
uniprot id: Q0AXZ9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335541:SWOL RS03920
gene id: 335541:SWOL_RS03920
uniprot id: Q0AYV7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

335541:SWOL RS08470
gene id: 335541:SWOL_RS08470
uniprot id: Q0AWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

335541:SWOL RS05115
gene id: 335541:SWOL_RS05115
uniprot id: Q0AY83
names: Similarity
messages: Belongs to the glutamine synthetase family.

335541:SWOL RS01140
gene id: 335541:SWOL_RS01140
uniprot id: Q0B0D6
names: Similarity
messages: Belongs to the HepT RNase toxin family.

335541:SWOL RS13585
gene id: 335541:SWOL_RS13585
uniprot id: Q0AX11
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS08955
gene id: 335541:SWOL_RS08955
uniprot id: Q0AW71
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335541:SWOL RS13435
gene id: 335541:SWOL_RS13435
uniprot id: Q0B010
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS02170
gene id: 335541:SWOL_RS02170
uniprot id: Q0AZU1
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS04640
gene id: 335541:SWOL_RS04640
uniprot id: Q0AYG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

335541:SWOL RS05210
gene id: 335541:SWOL_RS05210
uniprot id: Q0AY64
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335541:SWOL RS07855
gene id: 335541:SWOL_RS07855
uniprot id: Q0AWT6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335541:SWOL RS05170
gene id: 335541:SWOL_RS05170
uniprot id: Q0AY72
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335541:SWOL RS13170
gene id: 335541:SWOL_RS13170
uniprot id: Q0ATW9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS13320
gene id: 335541:SWOL_RS13320
uniprot id: Q0ATU1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

335541:SWOL RS13465
gene id: 335541:SWOL_RS13465
uniprot id: Q0AZC4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS12050
gene id: 335541:SWOL_RS12050
uniprot id: Q0AUI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

335541:SWOL RS05985
gene id: 335541:SWOL_RS05985
uniprot id: Q0AXS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Membrane

335541:SWOL RS08325
gene id: 335541:SWOL_RS08325
uniprot id: Q0AWJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS09875
gene id: 335541:SWOL_RS09875
uniprot id: Q0AVP5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

335541:SWOL RS06855
gene id: 335541:SWOL_RS06855
uniprot id: Q0AXC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

335541:SWOL RS08415
gene id: 335541:SWOL_RS08415
uniprot id: Q0AWH7
names: Similarity
messages: Belongs to the class-I fumarase family.

335541:SWOL RS10780
gene id: 335541:SWOL_RS10780
uniprot id: Q0AV79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04740
gene id: 335541:SWOL_RS04740
uniprot id: Q0AYF6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

335541:SWOL RS10830
gene id: 335541:SWOL_RS10830
uniprot id: Q0AV69
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

335541:SWOL RS05875
gene id: 335541:SWOL_RS05875
uniprot id: Q0AXU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

335541:SWOL RS13295
gene id: 335541:SWOL_RS13295
uniprot id: Q0ATU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

335541:SWOL RS03600
gene id: 335541:SWOL_RS03600
uniprot id: Q0AZ18
names: Similarity
messages: Belongs to the asparagine synthetase family.

335541:SWOL RS02880
gene id: 335541:SWOL_RS02880
uniprot id: Q0AZF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

335541:SWOL RS10445
gene id: 335541:SWOL_RS10445
uniprot id: Q0AVE0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

335541:SWOL RS12070
gene id: 335541:SWOL_RS12070
uniprot id: Q0AUI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

335541:SWOL RS02700
gene id: 335541:SWOL_RS02700
uniprot id: Q0AZI9
names: Similarity
messages: Belongs to the GSP E family.

335541:SWOL RS03870
gene id: 335541:SWOL_RS03870
uniprot id: Q0AYW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm

335541:SWOL RS04910
gene id: 335541:SWOL_RS04910
uniprot id: Q0AYC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

335541:SWOL RS02315
gene id: 335541:SWOL_RS02315
uniprot id: Q0AZR4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

335541:SWOL RS09995
gene id: 335541:SWOL_RS09995
uniprot id: Q0AVM3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Highly expressed during syntrophic growth with butyrate (at protein level). Seems to be constitutively expressed.
messages: Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the beta-keto thiolysis of acetoacetyl-CoA, leading to 2 acetyl-CoA molecules.

335541:SWOL RS07490
gene id: 335541:SWOL_RS07490
uniprot id: Q0AWZ8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

335541:SWOL RS04995
gene id: 335541:SWOL_RS04995
uniprot id: Q0AYA7
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

335541:SWOL RS02775
gene id: 335541:SWOL_RS02775
uniprot id: Q0AZH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

335541:SWOL RS03380
gene id: 335541:SWOL_RS03380
uniprot id: Q0AZ59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

335541:SWOL RS10235
gene id: 335541:SWOL_RS10235
uniprot id: Q0AVH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

335541:SWOL RS11015
gene id: 335541:SWOL_RS11015
uniprot id: Q0AV33
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS03290
gene id: 335541:SWOL_RS03290
uniprot id: Q0AZ77
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335541:SWOL RS04345
gene id: 335541:SWOL_RS04345
uniprot id: Q0AYM5
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

335541:SWOL RS02375
gene id: 335541:SWOL_RS02375
uniprot id: Q0AZQ1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

335541:SWOL RS12705
gene id: 335541:SWOL_RS12705
uniprot id: Q0AU62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

335541:SWOL RS02290
gene id: 335541:SWOL_RS02290
uniprot id: Q0AZR9
names: Caution
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

335541:SWOL RS12770
gene id: 335541:SWOL_RS12770
uniprot id: Q0AU49
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS09560
gene id: 335541:SWOL_RS09560
uniprot id: Q0AVV7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

335541:SWOL RS00410
gene id: 335541:SWOL_RS00410
uniprot id: Q0B0S9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

335541:SWOL RS02875
gene id: 335541:SWOL_RS02875
uniprot id: Q0AZF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

335541:SWOL RS10925
gene id: 335541:SWOL_RS10925
uniprot id: Q0AV50
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS00570
gene id: 335541:SWOL_RS00570
uniprot id: Q0B0P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

335541:SWOL RS04245
gene id: 335541:SWOL_RS04245
uniprot id: Q0AYP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

335541:SWOL RS01680
gene id: 335541:SWOL_RS01680
uniprot id: Q0B033
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS12060
gene id: 335541:SWOL_RS12060
uniprot id: Q0AUI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

335541:SWOL RS00835
gene id: 335541:SWOL_RS00835
uniprot id: Q0B0J5
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

335541:SWOL RS11925
gene id: 335541:SWOL_RS11925
uniprot id: Q0AUL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

335541:SWOL RS08485
gene id: 335541:SWOL_RS08485
uniprot id: Q0AWG3
names: Similarity
messages: Belongs to the UPF0758 family.

335541:SWOL RS09365
gene id: 335541:SWOL_RS09365
uniprot id: Q0AVZ5
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

335541:SWOL RS11860
gene id: 335541:SWOL_RS11860
uniprot id: Q0AUM5
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

335541:SWOL RS13160
gene id: 335541:SWOL_RS13160
uniprot id: Q0ATX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04200
gene id: 335541:SWOL_RS04200
uniprot id: Q0AYQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

335541:SWOL RS01755
gene id: 335541:SWOL_RS01755
uniprot id: Q0B017
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

335541:SWOL RS03400
gene id: 335541:SWOL_RS03400
uniprot id: Q0AZ55
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

335541:SWOL RS04800
gene id: 335541:SWOL_RS04800
uniprot id: Q0AYE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

335541:SWOL RS05250
gene id: 335541:SWOL_RS05250
uniprot id: Q0AY56
names: Similarity
messages: Belongs to the peptidase C40 family.

335541:SWOL RS09590
gene id: 335541:SWOL_RS09590
uniprot id: Q0AVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

335541:SWOL RS04100
gene id: 335541:SWOL_RS04100
uniprot id: Q0AYS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS01315
gene id: 335541:SWOL_RS01315
uniprot id: Q0B0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

335541:SWOL RS00550
gene id: 335541:SWOL_RS00550
uniprot id: Q0B0Q0
names: Similarity
messages: Belongs to the DHPS family.

335541:SWOL RS10050
gene id: 335541:SWOL_RS10050
uniprot id: Q0AVL2
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

335541:SWOL RS04905
gene id: 335541:SWOL_RS04905
uniprot id: Q0AYC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MurCDEF family. MurT subfamily.
messages: Forms a heterodimer with GatD.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue.

335541:SWOL RS03555
gene id: 335541:SWOL_RS03555
uniprot id: Q0AZ27
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335541:SWOL RS13100
gene id: 335541:SWOL_RS13100
uniprot id: Q0ATY1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

335541:SWOL RS11210
gene id: 335541:SWOL_RS11210
uniprot id: Q0AUZ4
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

335541:SWOL RS03485
gene id: 335541:SWOL_RS03485
uniprot id: Q0AZ40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

335541:SWOL RS11960
gene id: 335541:SWOL_RS11960
uniprot id: Q0AUK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

335541:SWOL RS03255
gene id: 335541:SWOL_RS03255
uniprot id: Q0AZ83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

335541:SWOL RS13650
gene id: 335541:SWOL_RS13650
uniprot id: Q0AW84
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS11120
gene id: 335541:SWOL_RS11120
uniprot id: Q0AV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

335541:SWOL RS02670
gene id: 335541:SWOL_RS02670
uniprot id: Q0AZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0316 family.
messages: Cell membrane

335541:SWOL RS01590
gene id: 335541:SWOL_RS01590
uniprot id: Q0B050
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

335541:SWOL RS09480
gene id: 335541:SWOL_RS09480
uniprot id: Q0AVX1
names: Similarity
messages: Belongs to the AOR/FOR family.

335541:SWOL RS02220
gene id: 335541:SWOL_RS02220
uniprot id: Q0AZT3
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS06330
gene id: 335541:SWOL_RS06330
uniprot id: Q0AXL3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

335541:SWOL RS11315
gene id: 335541:SWOL_RS11315
uniprot id: Q0AUX3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

335541:SWOL RS00100
gene id: 335541:SWOL_RS00100
uniprot id: Q0B0Y1
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

335541:SWOL RS12110
gene id: 335541:SWOL_RS12110
uniprot id: Q0AUH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

335541:SWOL RS06985
gene id: 335541:SWOL_RS06985
uniprot id: Q0AX96
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

335541:SWOL RS03125
gene id: 335541:SWOL_RS03125
uniprot id: Q0AZA8
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

335541:SWOL RS09925
gene id: 335541:SWOL_RS09925
uniprot id: Q0AVN6
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

335541:SWOL RS07430
gene id: 335541:SWOL_RS07430
uniprot id: Q0AX10
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
messages: Homodimer.

335541:SWOL RS13000
gene id: 335541:SWOL_RS13000
uniprot id: Q0AU00
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

335541:SWOL RS04925
gene id: 335541:SWOL_RS04925
uniprot id: Q0AYB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0291 family.
messages: Cytoplasm

335541:SWOL RS04260
gene id: 335541:SWOL_RS04260
uniprot id: Q0AYP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

335541:SWOL RS04875
gene id: 335541:SWOL_RS04875
uniprot id: Q0AYC9
names: Similarity
messages: Belongs to the EamA transporter family.

335541:SWOL RS02550
gene id: 335541:SWOL_RS02550
uniprot id: Q0AZL7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

335541:SWOL RS10840
gene id: 335541:SWOL_RS10840
uniprot id: Q0AV67
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

335541:SWOL RS06600
gene id: 335541:SWOL_RS06600
uniprot id: Q0AXG1
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

335541:SWOL RS01295
gene id: 335541:SWOL_RS01295
uniprot id: Q0B0A5
names: Similarity
messages: Belongs to the peptidase S41A family.

335541:SWOL RS06480
gene id: 335541:SWOL_RS06480
uniprot id: Q0AXI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

335541:SWOL RS09185
gene id: 335541:SWOL_RS09185
uniprot id: Q0AW32
names: Similarity
messages: Belongs to the GARS family.

335541:SWOL RS04470
gene id: 335541:SWOL_RS04470
uniprot id: Q0AYK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

335541:SWOL RS07470
gene id: 335541:SWOL_RS07470
uniprot id: Q0AX02
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

335541:SWOL RS10820
gene id: 335541:SWOL_RS10820
uniprot id: Q0AV71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS01025
gene id: 335541:SWOL_RS01025
uniprot id: Q0B0F9
names: Similarity
messages: Belongs to the bacterial flagellin family.

335541:SWOL RS02920
gene id: 335541:SWOL_RS02920
uniprot id: Q0AZE6
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS11870
gene id: 335541:SWOL_RS11870
uniprot id: Q0AUM3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

335541:SWOL RS06240
gene id: 335541:SWOL_RS06240
uniprot id: Q0AXN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

335541:SWOL RS11675
gene id: 335541:SWOL_RS11675
uniprot id: Q0AUQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

335541:SWOL RS04010
gene id: 335541:SWOL_RS04010
uniprot id: Q0AYT9
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

335541:SWOL RS06805
gene id: 335541:SWOL_RS06805
uniprot id: Q0AXD0
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

335541:SWOL RS07735
gene id: 335541:SWOL_RS07735
uniprot id: Q0AWV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

335541:SWOL RS08160
gene id: 335541:SWOL_RS08160
uniprot id: Q0AWM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

335541:SWOL RS01940
gene id: 335541:SWOL_RS01940
uniprot id: Q0AZY5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS00415
gene id: 335541:SWOL_RS00415
uniprot id: Q0B0S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

335541:SWOL RS06620
gene id: 335541:SWOL_RS06620
uniprot id: Q0AUU5
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

335541:SWOL RS06555
gene id: 335541:SWOL_RS06555
uniprot id: Q0AXH0
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

335541:SWOL RS10990
gene id: 335541:SWOL_RS10990
uniprot id: Q0AV37
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS09150
gene id: 335541:SWOL_RS09150
uniprot id: Q0AW39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

335541:SWOL RS12435
gene id: 335541:SWOL_RS12435
uniprot id: Q0AUB6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

335541:SWOL RS01405
gene id: 335541:SWOL_RS01405
uniprot id: Q0B085
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

335541:SWOL RS11000
gene id: 335541:SWOL_RS11000
uniprot id: Q0AV35
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

335541:SWOL RS12590
gene id: 335541:SWOL_RS12590
uniprot id: Q0AU85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
messages: Cell membrane
messages: Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).

335541:SWOL RS07660
gene id: 335541:SWOL_RS07660
uniprot id: Q0AWX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

335541:SWOL RS12280
gene id: 335541:SWOL_RS12280
uniprot id: Q0AUE7
names: Activity Regulation
names: Function
names: Similarity
messages: Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.

335541:SWOL RS08090
gene id: 335541:SWOL_RS08090
uniprot id: Q0AWN9
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

335541:SWOL RS08775
gene id: 335541:SWOL_RS08775
uniprot id: Q0AWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

335541:SWOL RS12090
gene id: 335541:SWOL_RS12090
uniprot id: Q0AUH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

335541:SWOL RS02055
gene id: 335541:SWOL_RS02055
uniprot id: Q0AZW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS10890
gene id: 335541:SWOL_RS10890
uniprot id: Q0AV57
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

335541:SWOL RS12535
gene id: 335541:SWOL_RS12535
uniprot id: Q0AU95
names: Similarity
messages: Belongs to the RpoE family.

335541:SWOL RS00975
gene id: 335541:SWOL_RS00975
uniprot id: Q0B0G8
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

335541:SWOL RS11920
gene id: 335541:SWOL_RS11920
uniprot id: Q0AUL3
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS01260
gene id: 335541:SWOL_RS01260
uniprot id: Q0B0B2
names: Similarity
messages: Belongs to the MotB family.

335541:SWOL RS00665
gene id: 335541:SWOL_RS00665
uniprot id: Q0B0M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

335541:SWOL RS02090
gene id: 335541:SWOL_RS02090
uniprot id: Q0AZV6
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

335541:SWOL RS04980
gene id: 335541:SWOL_RS04980
uniprot id: Q0AYA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

335541:SWOL RS04125
gene id: 335541:SWOL_RS04125
uniprot id: Q0AYR6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

335541:SWOL RS04795
gene id: 335541:SWOL_RS04795
uniprot id: Q0AYE5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. SigI subfamily.
messages: Cytoplasm
messages: Interacts with RsgI.
messages: Negatively regulated by the anti-sigma-I factor RsgI.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

335541:SWOL RS00035
gene id: 335541:SWOL_RS00035
uniprot id: Q0B0Z0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

335541:SWOL RS11100
gene id: 335541:SWOL_RS11100
uniprot id: Q0AV16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS11705
gene id: 335541:SWOL_RS11705
uniprot id: Q0AUQ1
names: Similarity
messages: Belongs to the UPF0758 family.

335541:SWOL RS02440
gene id: 335541:SWOL_RS02440
uniprot id: Q0AZN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

335541:SWOL RS03320
gene id: 335541:SWOL_RS03320
uniprot id: Q0AZ71
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335541:SWOL RS04745
gene id: 335541:SWOL_RS04745
uniprot id: Q0AYF5
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

335541:SWOL RS11730
gene id: 335541:SWOL_RS11730
uniprot id: Q0AUP6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

335541:SWOL RS10085
gene id: 335541:SWOL_RS10085
uniprot id: Q0AVK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

335541:SWOL RS01425
gene id: 335541:SWOL_RS01425
uniprot id: Q0B081
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

335541:SWOL RS10300
gene id: 335541:SWOL_RS10300
uniprot id: Q0AVG5
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

335541:SWOL RS08085
gene id: 335541:SWOL_RS08085
uniprot id: Q0AWP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS11065
gene id: 335541:SWOL_RS11065
uniprot id: Q0AV23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS09755
gene id: 335541:SWOL_RS09755
uniprot id: Q0AVR9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

335541:SWOL RS02980
gene id: 335541:SWOL_RS02980
uniprot id: Q0AZD7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

335541:SWOL RS11905
gene id: 335541:SWOL_RS11905
uniprot id: Q0AUL6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

335541:SWOL RS00310
gene id: 335541:SWOL_RS00310
uniprot id: Q0B0U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

335541:SWOL RS05690
gene id: 335541:SWOL_RS05690
uniprot id: Q0AXY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

335541:SWOL RS00420
gene id: 335541:SWOL_RS00420
uniprot id: Q0B0S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

335541:SWOL RS12995
gene id: 335541:SWOL_RS12995
uniprot id: Q0AU01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

335541:SWOL RS12685
gene id: 335541:SWOL_RS12685
uniprot id: Q0AU66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04960
gene id: 335541:SWOL_RS04960
uniprot id: Q0AYB3
names: Similarity
messages: Belongs to the histone deacetylase family.

335541:SWOL RS01575
gene id: 335541:SWOL_RS01575
uniprot id: Q0B053
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335541:SWOL RS12100
gene id: 335541:SWOL_RS12100
uniprot id: Q0AUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

335541:SWOL RS13285
gene id: 335541:SWOL_RS13285
uniprot id: Q0ATU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

335541:SWOL RS09160
gene id: 335541:SWOL_RS09160
uniprot id: Q0AW37
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

335541:SWOL RS04495
gene id: 335541:SWOL_RS04495
uniprot id: Q0AYJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

335541:SWOL RS09140
gene id: 335541:SWOL_RS09140
uniprot id: Q0AW41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

335541:SWOL RS13500
gene id: 335541:SWOL_RS13500
uniprot id: Q0AYN0
names: Similarity
messages: Belongs to the FlgD family.

335541:SWOL RS00140
gene id: 335541:SWOL_RS00140
uniprot id: Q0B0X4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

335541:SWOL RS00535
gene id: 335541:SWOL_RS00535
uniprot id: Q0B0Q3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

335541:SWOL RS04385
gene id: 335541:SWOL_RS04385
uniprot id: Q0AYL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

335541:SWOL RS09645
gene id: 335541:SWOL_RS09645
uniprot id: Q0AVT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm

335541:SWOL RS07335
gene id: 335541:SWOL_RS07335
uniprot id: Q0AX29
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ScpA family.
messages: Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.
messages: Cytoplasm
messages: Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.

335541:SWOL RS12510
gene id: 335541:SWOL_RS12510
uniprot id: Q0AUA0
names: Similarity
messages: Belongs to the peptidase S49 family.

335541:SWOL RS02475
gene id: 335541:SWOL_RS02475
uniprot id: Q0AZN1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS04590
gene id: 335541:SWOL_RS04590
uniprot id: Q0AYH7
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

335541:SWOL RS09985
gene id: 335541:SWOL_RS09985
uniprot id: Q0AVM5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA. Involved in the syntrophic growth of S.wolfei on butyrate in cooperation with methanogens or an appropriate hydrogen-scavenging bacterium, as part of the butyrate oxidation pathway.
messages: Cytoplasm
messages: Expressed during syntrophic growth with butyrate (at protein level). Seems to be constitutively expressed.

335541:SWOL RS01280
gene id: 335541:SWOL_RS01280
uniprot id: Q0B0A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

335541:SWOL RS00590
gene id: 335541:SWOL_RS00590
uniprot id: Q0B0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

335541:SWOL RS06845
gene id: 335541:SWOL_RS06845
uniprot id: Q0AXC4
names: Function
names: Subcellular Location Annotation
messages: ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
messages: Cytoplasm

335541:SWOL RS03535
gene id: 335541:SWOL_RS03535
uniprot id: Q0AZ30
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS06455
gene id: 335541:SWOL_RS06455
uniprot id: Q0AXI9
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

335541:SWOL RS06155
gene id: 335541:SWOL_RS06155
uniprot id: Q0AXP6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Homodimer or homotetramer.

335541:SWOL RS01035
gene id: 335541:SWOL_RS01035
uniprot id: Q0B0F7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

335541:SWOL RS05885
gene id: 335541:SWOL_RS05885
uniprot id: Q0AXU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS01905
gene id: 335541:SWOL_RS01905
uniprot id: Q0AZZ2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

335541:SWOL RS03715
gene id: 335541:SWOL_RS03715
uniprot id: Q0AYZ6
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

335541:SWOL RS13115
gene id: 335541:SWOL_RS13115
uniprot id: Q0ATX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

335541:SWOL RS04585
gene id: 335541:SWOL_RS04585
uniprot id: Q0AYH8
names: Similarity
messages: Belongs to the peptidase M16 family.

335541:SWOL RS13730
gene id: 335541:SWOL_RS13730
uniprot id: Q0AVA0
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS02385
gene id: 335541:SWOL_RS02385
uniprot id: Q0AZP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

335541:SWOL RS08285
gene id: 335541:SWOL_RS08285
uniprot id: Q0AWK2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

335541:SWOL RS04190
gene id: 335541:SWOL_RS04190
uniprot id: Q0AYQ4
names: Similarity
messages: Belongs to the UPF0749 family.

335541:SWOL RS10565
gene id: 335541:SWOL_RS10565
uniprot id: Q0AVB8
names: Similarity
names: Subunit
messages: Belongs to the MtrB family.
messages: Oligomer of 11 identical subunits arranged in doughnut-like structure.

335541:SWOL RS02180
gene id: 335541:SWOL_RS02180
uniprot id: Q0AZT9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

335541:SWOL RS11095
gene id: 335541:SWOL_RS11095
uniprot id: Q0AV17
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

335541:SWOL RS05150
gene id: 335541:SWOL_RS05150
uniprot id: Q0AY76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

335541:SWOL RS07845
gene id: 335541:SWOL_RS07845
uniprot id: Q0AWT8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

335541:SWOL RS00600
gene id: 335541:SWOL_RS00600
uniprot id: Q0B0P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

335541:SWOL RS11080
gene id: 335541:SWOL_RS11080
uniprot id: Q0AV20
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homodimer.

335541:SWOL RS04140
gene id: 335541:SWOL_RS04140
uniprot id: Q0AYR4
names: Similarity
messages: Belongs to the transpeptidase family.

335541:SWOL RS12730
gene id: 335541:SWOL_RS12730
uniprot id: Q0AU57
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS11285
gene id: 335541:SWOL_RS11285
uniprot id: Q0AUX9
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS09565
gene id: 335541:SWOL_RS09565
uniprot id: Q0AVV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

335541:SWOL RS09610
gene id: 335541:SWOL_RS09610
uniprot id: Q0AVU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

335541:SWOL RS08935
gene id: 335541:SWOL_RS08935
uniprot id: Q0AW75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

335541:SWOL RS02390
gene id: 335541:SWOL_RS02390
uniprot id: Q0AZP8
names: Similarity
messages: Belongs to the UPF0473 family.

335541:SWOL RS12105
gene id: 335541:SWOL_RS12105
uniprot id: Q0AUH6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

335541:SWOL RS03880
gene id: 335541:SWOL_RS03880
uniprot id: Q0AYW5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

335541:SWOL RS07860
gene id: 335541:SWOL_RS07860
uniprot id: Q0AWT5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335541:SWOL RS06070
gene id: 335541:SWOL_RS06070
uniprot id: Q0AXR2
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

335541:SWOL RS12065
gene id: 335541:SWOL_RS12065
uniprot id: Q0AUI4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

335541:SWOL RS04520
gene id: 335541:SWOL_RS04520
uniprot id: Q0AYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

335541:SWOL RS12550
gene id: 335541:SWOL_RS12550
uniprot id: Q0AU92
names: Cofactor
messages: Binds 1 zinc ion per subunit.

335541:SWOL RS08095
gene id: 335541:SWOL_RS08095
uniprot id: Q0AWN8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

335541:SWOL RS08940
gene id: 335541:SWOL_RS08940
uniprot id: Q0AW74
names: Similarity
messages: Belongs to the peptidase S41A family.

335541:SWOL RS12025
gene id: 335541:SWOL_RS12025
uniprot id: Q0AUJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

335541:SWOL RS05330
gene id: 335541:SWOL_RS05330
uniprot id: Q0AY41
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS11255
gene id: 335541:SWOL_RS11255
uniprot id: Q0AUY5
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS09780
gene id: 335541:SWOL_RS09780
uniprot id: Q0AVR4
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

335541:SWOL RS11125
gene id: 335541:SWOL_RS11125
uniprot id: Q0AV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

335541:SWOL RS01450
gene id: 335541:SWOL_RS01450
uniprot id: Q0B076
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

335541:SWOL RS03825
gene id: 335541:SWOL_RS03825
uniprot id: Q0AYX4
names: Similarity
messages: Belongs to the asp23 family.

335541:SWOL RS01925
gene id: 335541:SWOL_RS01925
uniprot id: Q0AZY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335541:SWOL RS03310
gene id: 335541:SWOL_RS03310
uniprot id: Q0AZ73
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS11525
gene id: 335541:SWOL_RS11525
uniprot id: Q0AUT3
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS08455
gene id: 335541:SWOL_RS08455
uniprot id: Q0AWG9
names: Function
names: Similarity
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.

335541:SWOL RS01385
gene id: 335541:SWOL_RS01385
uniprot id: Q0B089
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335541:SWOL RS01675
gene id: 335541:SWOL_RS01675
uniprot id: Q0B034
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

335541:SWOL RS04915
gene id: 335541:SWOL_RS04915
uniprot id: Q0AYC1
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

335541:SWOL RS10805
gene id: 335541:SWOL_RS10805
uniprot id: Q0AV74
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

335541:SWOL RS05650
gene id: 335541:SWOL_RS05650
uniprot id: Q0AXY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

335541:SWOL RS03980
gene id: 335541:SWOL_RS03980
uniprot id: Q0AYU5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS04615
gene id: 335541:SWOL_RS04615
uniprot id: Q0AYH2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

335541:SWOL RS00540
gene id: 335541:SWOL_RS00540
uniprot id: Q0B0Q2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS12125
gene id: 335541:SWOL_RS12125
uniprot id: Q0AUH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

335541:SWOL RS11980
gene id: 335541:SWOL_RS11980
uniprot id: Q0AUK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS11590
gene id: 335541:SWOL_RS11590
uniprot id: Q0AUS2
names: Similarity
messages: Belongs to the UPF0145 family.

335541:SWOL RS08505
gene id: 335541:SWOL_RS08505
uniprot id: Q0AWF9
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS05945
gene id: 335541:SWOL_RS05945
uniprot id: Q0AXT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

335541:SWOL RS10600
gene id: 335541:SWOL_RS10600
uniprot id: Q0AVB1
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS07390
gene id: 335541:SWOL_RS07390
uniprot id: Q0AX18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

335541:SWOL RS04150
gene id: 335541:SWOL_RS04150
uniprot id: Q0AYR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

335541:SWOL RS02455
gene id: 335541:SWOL_RS02455
uniprot id: Q0AUU4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

335541:SWOL RS01760
gene id: 335541:SWOL_RS01760
uniprot id: Q0B016
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

335541:SWOL RS05785
gene id: 335541:SWOL_RS05785
uniprot id: Q0AXW4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

335541:SWOL RS03985
gene id: 335541:SWOL_RS03985
uniprot id: Q0AYU4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335541:SWOL RS11220
gene id: 335541:SWOL_RS11220
uniprot id: Q0AUZ2
names: Similarity
messages: Belongs to the histone deacetylase family.

335541:SWOL RS08750
gene id: 335541:SWOL_RS08750
uniprot id: Q0AWB3
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

335541:SWOL RS06990
gene id: 335541:SWOL_RS06990
uniprot id: Q0AX95
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

335541:SWOL RS08475
gene id: 335541:SWOL_RS08475
uniprot id: Q0AWG5
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

335541:SWOL RS09210
gene id: 335541:SWOL_RS09210
uniprot id: Q0AW27
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

335541:SWOL RS10310
gene id: 335541:SWOL_RS10310
uniprot id: Q0AVG3
names: Subcellular Location Annotation
messages: Cell membrane

335541:SWOL RS09070
gene id: 335541:SWOL_RS09070
uniprot id: Q0AW54
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated Csm5 family.
messages: This subunit might be involved in maturation of a crRNA intermediate to its mature form.

335541:SWOL RS02190
gene id: 335541:SWOL_RS02190
uniprot id: Q0AZT7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

335541:SWOL RS12140
gene id: 335541:SWOL_RS12140
uniprot id: Q0AUG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

335541:SWOL RS10910
gene id: 335541:SWOL_RS10910
uniprot id: Q0AV53
names: Similarity
messages: Belongs to the EamA transporter family.

335541:SWOL RS11105
gene id: 335541:SWOL_RS11105
uniprot id: Q0AV15
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

335541:SWOL RS09655
gene id: 335541:SWOL_RS09655
uniprot id: Q0AVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

335541:SWOL RS05560
gene id: 335541:SWOL_RS05560
uniprot id: Q0AY03
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

335541:SWOL RS09165
gene id: 335541:SWOL_RS09165
uniprot id: Q0AW36
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

335541:SWOL RS01380
gene id: 335541:SWOL_RS01380
uniprot id: Q0B090
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

335541:SWOL RS01855
gene id: 335541:SWOL_RS01855
uniprot id: Q0B002
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

335541:SWOL RS11010
gene id: 335541:SWOL_RS11010
uniprot id: Q0AV34
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335541:SWOL RS06595
gene id: 335541:SWOL_RS06595
uniprot id: Q0AXG2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS00950
gene id: 335541:SWOL_RS00950
uniprot id: Q0B0H3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335541:SWOL RS05175
gene id: 335541:SWOL_RS05175
uniprot id: Q0AY71
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335541:SWOL RS13095
gene id: 335541:SWOL_RS13095
uniprot id: Q0ATY2
names: Similarity
messages: Belongs to the peptidase S16 family.

335541:SWOL RS11880
gene id: 335541:SWOL_RS11880
uniprot id: Q0AUM1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

335541:SWOL RS02860
gene id: 335541:SWOL_RS02860
uniprot id: Q0AZF7
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

335541:SWOL RS04510
gene id: 335541:SWOL_RS04510
uniprot id: Q0AYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

335541:SWOL RS13315
gene id: 335541:SWOL_RS13315
uniprot id: Q0ATU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

335541:SWOL RS12540
gene id: 335541:SWOL_RS12540
uniprot id: Q0AU94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS10680
gene id: 335541:SWOL_RS10680
uniprot id: Q0AV96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

335541:SWOL RS06545
gene id: 335541:SWOL_RS06545
uniprot id: Q0AXH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

335541:SWOL RS05575
gene id: 335541:SWOL_RS05575
uniprot id: Q0AY00
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

335541:SWOL RS06610
gene id: 335541:SWOL_RS06610
uniprot id: Q0AXF9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

335541:SWOL RS12165
gene id: 335541:SWOL_RS12165
uniprot id: Q0AUG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

335541:SWOL RS13280
gene id: 335541:SWOL_RS13280
uniprot id: Q0ATU8
names: Similarity
messages: Belongs to the ParB family.

335541:SWOL RS04465
gene id: 335541:SWOL_RS04465
uniprot id: Q0AYK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

335541:SWOL RS01040
gene id: 335541:SWOL_RS01040
uniprot id: Q0B0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

335541:SWOL RS02235
gene id: 335541:SWOL_RS02235
uniprot id: Q0AZT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

335541:SWOL RS03265
gene id: 335541:SWOL_RS03265
uniprot id: Q0AZ81
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

335541:SWOL RS10900
gene id: 335541:SWOL_RS10900
uniprot id: Q0AV55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS07955
gene id: 335541:SWOL_RS07955
uniprot id: Q0AWR6
names: Similarity
messages: Belongs to the DtxR/MntR family.

335541:SWOL RS03370
gene id: 335541:SWOL_RS03370
uniprot id: Q0AZ61
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335541:SWOL RS11930
gene id: 335541:SWOL_RS11930
uniprot id: Q0AUL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).

335541:SWOL RS03315
gene id: 335541:SWOL_RS03315
uniprot id: Q0AZ72
names: Similarity
messages: Belongs to the UPF0342 family.

335541:SWOL RS08560
gene id: 335541:SWOL_RS08560
uniprot id: Q0AWE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

335541:SWOL RS00635
gene id: 335541:SWOL_RS00635
uniprot id: Q0B0N3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS01920
gene id: 335541:SWOL_RS01920
uniprot id: Q0AZY9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335541:SWOL RS03375
gene id: 335541:SWOL_RS03375
uniprot id: Q0AZ60
names: Similarity
messages: Belongs to the pyruvoyl-dependent arginine decarboxylase family.

335541:SWOL RS12345
gene id: 335541:SWOL_RS12345
uniprot id: Q0AUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

335541:SWOL RS09830
gene id: 335541:SWOL_RS09830
uniprot id: Q0AVQ4
names: Subcellular Location Annotation
messages: Cell membrane

335541:SWOL RS06140
gene id: 335541:SWOL_RS06140
uniprot id: Q0AXP9
names: Cofactor
names: Function
names: Subunit
messages: Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.
messages: Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
messages: Heterodimer of the IorA and IorB subunits.

335541:SWOL RS09765
gene id: 335541:SWOL_RS09765
uniprot id: Q0AVR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS01750
gene id: 335541:SWOL_RS01750
uniprot id: Q0B018
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

335541:SWOL RS04975
gene id: 335541:SWOL_RS04975
uniprot id: Q0AYB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

335541:SWOL RS08195
gene id: 335541:SWOL_RS08195
uniprot id: Q0AWL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

335541:SWOL RS11655
gene id: 335541:SWOL_RS11655
uniprot id: Q0AUR1
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

335541:SWOL RS11875
gene id: 335541:SWOL_RS11875
uniprot id: Q0AUM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

335541:SWOL RS11505
gene id: 335541:SWOL_RS11505
uniprot id: Q0AUT7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

335541:SWOL RS08170
gene id: 335541:SWOL_RS08170
uniprot id: Q0AWM3
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

335541:SWOL RS03450
gene id: 335541:SWOL_RS03450
uniprot id: Q0AZ45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

335541:SWOL RS05995
gene id: 335541:SWOL_RS05995
uniprot id: Q0AXS4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

335541:SWOL RS12275
gene id: 335541:SWOL_RS12275
uniprot id: Q0AUE8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

335541:SWOL RS08145
gene id: 335541:SWOL_RS08145
uniprot id: Q0AWM8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

335541:SWOL RS05740
gene id: 335541:SWOL_RS05740
uniprot id: Q0AXX2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic Ku family.
messages: Homodimer. Interacts with LigD.
messages: With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.

335541:SWOL RS09215
gene id: 335541:SWOL_RS09215
uniprot id: Q0AW26
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

335541:SWOL RS12325
gene id: 335541:SWOL_RS12325
uniprot id: Q0AUD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS02990
gene id: 335541:SWOL_RS02990
uniprot id: Q0AZD5
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cytoplasm
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS05460
gene id: 335541:SWOL_RS05460
uniprot id: Q0AY20
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

335541:SWOL RS04160
gene id: 335541:SWOL_RS04160
uniprot id: Q0AYR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

335541:SWOL RS07410
gene id: 335541:SWOL_RS07410
uniprot id: Q0AX14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

335541:SWOL RS01220
gene id: 335541:SWOL_RS01220
uniprot id: Q0B0C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

335541:SWOL RS01250
gene id: 335541:SWOL_RS01250
uniprot id: Q0B0B4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

335541:SWOL RS07725
gene id: 335541:SWOL_RS07725
uniprot id: Q0AWV9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

335541:SWOL RS07290
gene id: 335541:SWOL_RS07290
uniprot id: Q0AX38
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

335541:SWOL RS00015
gene id: 335541:SWOL_RS00015
uniprot id: Q0B0Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

335541:SWOL RS06290
gene id: 335541:SWOL_RS06290
uniprot id: Q0AXM1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

335541:SWOL RS03420
gene id: 335541:SWOL_RS03420
uniprot id: Q0AZ51
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

335541:SWOL RS00435
gene id: 335541:SWOL_RS00435
uniprot id: Q0B0S3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

335541:SWOL RS07785
gene id: 335541:SWOL_RS07785
uniprot id: Q0AWU6
names: Similarity
messages: Belongs to the UPF0178 family.

335541:SWOL RS13205
gene id: 335541:SWOL_RS13205
uniprot id: Q0ATW3
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS06520
gene id: 335541:SWOL_RS06520
uniprot id: Q0AXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

335541:SWOL RS07295
gene id: 335541:SWOL_RS07295
uniprot id: Q0AX37
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS07345
gene id: 335541:SWOL_RS07345
uniprot id: Q0AX27
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

335541:SWOL RS04550
gene id: 335541:SWOL_RS04550
uniprot id: Q0AYI5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

335541:SWOL RS12080
gene id: 335541:SWOL_RS12080
uniprot id: Q0AUI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

335541:SWOL RS09555
gene id: 335541:SWOL_RS09555
uniprot id: Q0AVV8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

335541:SWOL RS02350
gene id: 335541:SWOL_RS02350
uniprot id: Q0AZQ7
names: Similarity
messages: Belongs to the thioredoxin family.

335541:SWOL RS09810
gene id: 335541:SWOL_RS09810
uniprot id: Q0AVQ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

335541:SWOL RS02120
gene id: 335541:SWOL_RS02120
uniprot id: Q0AZV1
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS03040
gene id: 335541:SWOL_RS03040
uniprot id: Q0AZC5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS04450
gene id: 335541:SWOL_RS04450
uniprot id: Q0AYK4
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

335541:SWOL RS07760
gene id: 335541:SWOL_RS07760
uniprot id: Q0AWV2
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

335541:SWOL RS00710
gene id: 335541:SWOL_RS00710
uniprot id: Q0B0L8
names: Similarity
messages: Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.

335541:SWOL RS11465
gene id: 335541:SWOL_RS11465
uniprot id: Q0AUU5
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

335541:SWOL RS09445
gene id: 335541:SWOL_RS09445
uniprot id: Q0AVX8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335541:SWOL RS09190
gene id: 335541:SWOL_RS09190
uniprot id: Q0AW31
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

335541:SWOL RS00485
gene id: 335541:SWOL_RS00485
uniprot id: Q0B0R4
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335541:SWOL RS04170
gene id: 335541:SWOL_RS04170
uniprot id: Q0AYQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

335541:SWOL RS11500
gene id: 335541:SWOL_RS11500
uniprot id: Q0AUT8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

335541:SWOL RS04305
gene id: 335541:SWOL_RS04305
uniprot id: Q0AYN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS10500
gene id: 335541:SWOL_RS10500
uniprot id: Q0AVC9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

335541:SWOL RS06120
gene id: 335541:SWOL_RS06120
uniprot id: Q0AXQ3
names: Similarity
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Spore germination protein (SGP) (TC 2.A.3.9) family.

335541:SWOL RS00585
gene id: 335541:SWOL_RS00585
uniprot id: Q0B0P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

335541:SWOL RS01205
gene id: 335541:SWOL_RS01205
uniprot id: Q0B0C3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335541:SWOL RS09520
gene id: 335541:SWOL_RS09520
uniprot id: Q0AVW5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS06345
gene id: 335541:SWOL_RS06345
uniprot id: Q0AXL0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS10790
gene id: 335541:SWOL_RS10790
uniprot id: Q0AV77
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

335541:SWOL RS06820
gene id: 335541:SWOL_RS06820
uniprot id: Q0AXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

335541:SWOL RS12250
gene id: 335541:SWOL_RS12250
uniprot id: Q0AUF3
names: Similarity
messages: Belongs to the ycf81 family.

335541:SWOL RS12795
gene id: 335541:SWOL_RS12795
uniprot id: Q0AU44
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

335541:SWOL RS08175
gene id: 335541:SWOL_RS08175
uniprot id: Q0AWM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

335541:SWOL RS04880
gene id: 335541:SWOL_RS04880
uniprot id: Q0AYC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

335541:SWOL RS07370
gene id: 335541:SWOL_RS07370
uniprot id: Q0AX22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

335541:SWOL RS04265
gene id: 335541:SWOL_RS04265
uniprot id: Q0AYP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CodY family.
messages: Cytoplasm
messages: DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.

335541:SWOL RS10615
gene id: 335541:SWOL_RS10615
uniprot id: Q0AVA9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335541:SWOL RS08100
gene id: 335541:SWOL_RS08100
uniprot id: Q0AWN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

335541:SWOL RS03500
gene id: 335541:SWOL_RS03500
uniprot id: Q0AZ37
names: Similarity
messages: Belongs to the Ahb/Nir family.

335541:SWOL RS12170
gene id: 335541:SWOL_RS12170
uniprot id: Q0AUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

335541:SWOL RS06955
gene id: 335541:SWOL_RS06955
uniprot id: Q0AXA2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

335541:SWOL RS09050
gene id: 335541:SWOL_RS09050
uniprot id: Q0AW58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

335541:SWOL RS04830
gene id: 335541:SWOL_RS04830
uniprot id: Q0AYD8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS08200
gene id: 335541:SWOL_RS08200
uniprot id: Q0AWL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

335541:SWOL RS06285
gene id: 335541:SWOL_RS06285
uniprot id: Q0AXM2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

335541:SWOL RS03820
gene id: 335541:SWOL_RS03820
uniprot id: Q0AYX5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

335541:SWOL RS11250
gene id: 335541:SWOL_RS11250
uniprot id: Q0AUY6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS01155
gene id: 335541:SWOL_RS01155
uniprot id: Q0B0D3
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

335541:SWOL RS04500
gene id: 335541:SWOL_RS04500
uniprot id: Q0AYJ4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS03860
gene id: 335541:SWOL_RS03860
uniprot id: Q0AYW8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS12245
gene id: 335541:SWOL_RS12245
uniprot id: Q0AUF4
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

335541:SWOL RS03240
gene id: 335541:SWOL_RS03240
uniprot id: Q0AZ86
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

335541:SWOL RS12700
gene id: 335541:SWOL_RS12700
uniprot id: Q0AU63
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

335541:SWOL RS02490
gene id: 335541:SWOL_RS02490
uniprot id: Q0AZM8
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

335541:SWOL RS13125
gene id: 335541:SWOL_RS13125
uniprot id: Q0ATX6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

335541:SWOL RS11165
gene id: 335541:SWOL_RS11165
uniprot id: Q0AV03
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

335541:SWOL RS12055
gene id: 335541:SWOL_RS12055
uniprot id: Q0AUI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

335541:SWOL RS13005
gene id: 335541:SWOL_RS13005
uniprot id: Q0ATZ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

335541:SWOL RS07340
gene id: 335541:SWOL_RS07340
uniprot id: Q0AX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04535
gene id: 335541:SWOL_RS04535
uniprot id: Q0AYI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

335541:SWOL RS03900
gene id: 335541:SWOL_RS03900
uniprot id: Q0AYW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

335541:SWOL RS05305
gene id: 335541:SWOL_RS05305
uniprot id: Q0AY46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

335541:SWOL RS08155
gene id: 335541:SWOL_RS08155
uniprot id: Q0AWM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

335541:SWOL RS00990
gene id: 335541:SWOL_RS00990
uniprot id: Q0B0G6
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS06280
gene id: 335541:SWOL_RS06280
uniprot id: Q0AXM3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

335541:SWOL RS04645
gene id: 335541:SWOL_RS04645
uniprot id: Q0AYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

335541:SWOL RS02660
gene id: 335541:SWOL_RS02660
uniprot id: Q0AZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

335541:SWOL RS09320
gene id: 335541:SWOL_RS09320
uniprot id: Q0AW04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

335541:SWOL RS10560
gene id: 335541:SWOL_RS10560
uniprot id: Q0AVB9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS10670
gene id: 335541:SWOL_RS10670
uniprot id: Q0AV98
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335541:SWOL RS03725
gene id: 335541:SWOL_RS03725
uniprot id: Q0AYZ4
names: Function
names: Similarity
messages: Belongs to the 'phage' integrase family.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.

335541:SWOL RS05775
gene id: 335541:SWOL_RS05775
uniprot id: Q0AXW6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

335541:SWOL RS06355
gene id: 335541:SWOL_RS06355
uniprot id: Q0AXK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

335541:SWOL RS09550
gene id: 335541:SWOL_RS09550
uniprot id: Q0AVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

335541:SWOL RS01660
gene id: 335541:SWOL_RS01660
uniprot id: Q0B038
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS08705
gene id: 335541:SWOL_RS08705
uniprot id: Q0AWC2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

335541:SWOL RS13235
gene id: 335541:SWOL_RS13235
uniprot id: Q0ATV7
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

335541:SWOL RS11070
gene id: 335541:SWOL_RS11070
uniprot id: Q0AV22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335541:SWOL RS02610
gene id: 335541:SWOL_RS02610
uniprot id: Q0AZK4
names: Similarity
messages: Belongs to the HsdR family.

335541:SWOL RS11530
gene id: 335541:SWOL_RS11530
uniprot id: Q0AUT2
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS12495
gene id: 335541:SWOL_RS12495
uniprot id: Q0AUA4
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

335541:SWOL RS11205
gene id: 335541:SWOL_RS11205
uniprot id: Q0AUZ5
names: Similarity
messages: Belongs to the hemerythrin family.

335541:SWOL RS03145
gene id: 335541:SWOL_RS03145
uniprot id: Q0AZA4
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

335541:SWOL RS02685
gene id: 335541:SWOL_RS02685
uniprot id: Q0AZJ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

335541:SWOL RS02910
gene id: 335541:SWOL_RS02910
uniprot id: Q0AZE8
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

335541:SWOL RS12425
gene id: 335541:SWOL_RS12425
uniprot id: Q0AUB8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

335541:SWOL RS12605
gene id: 335541:SWOL_RS12605
uniprot id: Q0AU82
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

335541:SWOL RS02680
gene id: 335541:SWOL_RS02680
uniprot id: Q0AZJ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335541:SWOL RS02460
gene id: 335541:SWOL_RS02460
uniprot id: Q0AUU5
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

335541:SWOL RS01375
gene id: 335541:SWOL_RS01375
uniprot id: Q0B091
names: Similarity
messages: Belongs to the sigma-54 factor family.

335541:SWOL RS02760
gene id: 335541:SWOL_RS02760
uniprot id: Q0AZH7
names: Similarity
messages: Belongs to the peptidase U62 family.

335541:SWOL RS12360
gene id: 335541:SWOL_RS12360
uniprot id: Q0AUD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

335541:SWOL RS05685
gene id: 335541:SWOL_RS05685
uniprot id: Q0AXY2
names: Similarity
messages: Belongs to the thymidine kinase family.

335541:SWOL RS08845
gene id: 335541:SWOL_RS08845
uniprot id: Q0AW94
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS00185
gene id: 335541:SWOL_RS00185
uniprot id: Q0B0W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

335541:SWOL RS05525
gene id: 335541:SWOL_RS05525
uniprot id: Q0AY08
names: Similarity
messages: Belongs to the peptidase S8 family.

335541:SWOL RS12015
gene id: 335541:SWOL_RS12015
uniprot id: Q0AUJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

335541:SWOL RS08070
gene id: 335541:SWOL_RS08070
uniprot id: Q0AWP3
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

335541:SWOL RS00340
gene id: 335541:SWOL_RS00340
uniprot id: Q0B0U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

335541:SWOL RS08400
gene id: 335541:SWOL_RS08400
uniprot id: Q0AWH9
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS09540
gene id: 335541:SWOL_RS09540
uniprot id: Q0AVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

335541:SWOL RS06435
gene id: 335541:SWOL_RS06435
uniprot id: Q0AVI1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

335541:SWOL RS00060
gene id: 335541:SWOL_RS00060
uniprot id: Q0B0Y5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

335541:SWOL RS11940
gene id: 335541:SWOL_RS11940
uniprot id: Q0AUK9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

335541:SWOL RS02305
gene id: 335541:SWOL_RS02305
uniprot id: Q0AZR6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

335541:SWOL RS06125
gene id: 335541:SWOL_RS06125
uniprot id: Q0AXQ2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

335541:SWOL RS04275
gene id: 335541:SWOL_RS04275
uniprot id: Q0AYN8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

335541:SWOL RS12485
gene id: 335541:SWOL_RS12485
uniprot id: Q0AUA6
names: Similarity
messages: Belongs to the FBPase class 2 family.

335541:SWOL RS13400
gene id: 335541:SWOL_RS13400
uniprot id: Q0B0G0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

335541:SWOL RS01955
gene id: 335541:SWOL_RS01955
uniprot id: Q0AZY2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS06130
gene id: 335541:SWOL_RS06130
uniprot id: Q0AXQ1
names: Similarity
messages: Belongs to the GerABKA family.

335541:SWOL RS03445
gene id: 335541:SWOL_RS03445
uniprot id: Q0AZ46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

335541:SWOL RS03525
gene id: 335541:SWOL_RS03525
uniprot id: Q0AZ32
names: Cofactor
names: Function
names: Induction
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Highly expressed during syntrophic growth with butyrate (at protein level) (PubMed:19648244, PubMed:23468890). Seems to be constitutively expressed (PubMed:23468890).
messages: Might constitute a membrane-associated complex with EtfA (Swol_0697), EtfB (Swol_0696), and the butyryl-CoA dehydrogenase Swol_1933 and/or Swol_2052.
messages: Oxidoreductase involved in syntrophic growth of S.wolfei with butyrate. Is presumed to link the electron flow from butyryl-CoA dehydrogenases to the membrane, in conjunction with the electron transfer flavoprotein EtfAB. May transfer electrons to the menaquinone pool of the membrane.

335541:SWOL RS04950
gene id: 335541:SWOL_RS04950
uniprot id: Q0AYB5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

335541:SWOL RS11085
gene id: 335541:SWOL_RS11085
uniprot id: Q0AV19
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH or NADH to yield (R)-2,3-dihydroxy-isovalerate.

335541:SWOL RS07405
gene id: 335541:SWOL_RS07405
uniprot id: Q0AX15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

335541:SWOL RS11915
gene id: 335541:SWOL_RS11915
uniprot id: Q0AUL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

335541:SWOL RS09055
gene id: 335541:SWOL_RS09055
uniprot id: Q0AW57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

335541:SWOL RS02400
gene id: 335541:SWOL_RS02400
uniprot id: Q0AZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

335541:SWOL RS08640
gene id: 335541:SWOL_RS08640
uniprot id: Q0AWD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.

335541:SWOL RS02415
gene id: 335541:SWOL_RS02415
uniprot id: Q0AZP3
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

335541:SWOL RS04965
gene id: 335541:SWOL_RS04965
uniprot id: Q0AYB2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

335541:SWOL RS04480
gene id: 335541:SWOL_RS04480
uniprot id: Q0AYJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

335541:SWOL RS11135
gene id: 335541:SWOL_RS11135
uniprot id: Q0AV09
names: Similarity
messages: Belongs to the phosphohexose mutase family.

335541:SWOL RS13210
gene id: 335541:SWOL_RS13210
uniprot id: Q0ATW2
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS07645
gene id: 335541:SWOL_RS07645
uniprot id: Q0AWX4
names: Similarity
messages: Belongs to the UPF0102 family.

335541:SWOL RS05550
gene id: 335541:SWOL_RS05550
uniprot id: Q0AY05
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS04215
gene id: 335541:SWOL_RS04215
uniprot id: Q0AYP9
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

335541:SWOL RS08465
gene id: 335541:SWOL_RS08465
uniprot id: Q0AWG7
names: Similarity
messages: Belongs to the transpeptidase family.

335541:SWOL RS12400
gene id: 335541:SWOL_RS12400
uniprot id: Q0AUC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS12150
gene id: 335541:SWOL_RS12150
uniprot id: Q0AUG7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

335541:SWOL RS03425
gene id: 335541:SWOL_RS03425
uniprot id: Q0AZ50
names: Similarity
messages: Belongs to the UbiD family.

335541:SWOL RS05870
gene id: 335541:SWOL_RS05870
uniprot id: Q0AXU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddA subfamily.
messages: Heterodimer of AddA and AddB/RexB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.

335541:SWOL RS01900
gene id: 335541:SWOL_RS01900
uniprot id: Q0AZZ3
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

335541:SWOL RS10865
gene id: 335541:SWOL_RS10865
uniprot id: Q0AV62
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

335541:SWOL RS00525
gene id: 335541:SWOL_RS00525
uniprot id: Q0B0Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

335541:SWOL RS01390
gene id: 335541:SWOL_RS01390
uniprot id: Q0B088
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

335541:SWOL RS07455
gene id: 335541:SWOL_RS07455
uniprot id: Q0AX05
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

335541:SWOL RS05845
gene id: 335541:SWOL_RS05845
uniprot id: Q0AXV2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. AddB/RexB type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Heterodimer of AddA and AddB.
messages: The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.

335541:SWOL RS02450
gene id: 335541:SWOL_RS02450
uniprot id: Q0AZN6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

335541:SWOL RS08190
gene id: 335541:SWOL_RS08190
uniprot id: Q0AWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

335541:SWOL RS12300
gene id: 335541:SWOL_RS12300
uniprot id: Q0AUE3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.
messages: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.

335541:SWOL RS10940
gene id: 335541:SWOL_RS10940
uniprot id: Q0AV47
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

335541:SWOL RS06460
gene id: 335541:SWOL_RS06460
uniprot id: Q0AXI8
names: Similarity
messages: Belongs to the CinA family.

335541:SWOL RS11885
gene id: 335541:SWOL_RS11885
uniprot id: Q0AUM0
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

335541:SWOL RS05890
gene id: 335541:SWOL_RS05890
uniprot id: Q0AXU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

335541:SWOL RS03565
gene id: 335541:SWOL_RS03565
uniprot id: Q0AZ25
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

335541:SWOL RS06500
gene id: 335541:SWOL_RS06500
uniprot id: Q0AXI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

335541:SWOL RS00040
gene id: 335541:SWOL_RS00040
uniprot id: Q0B0Y9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

335541:SWOL RS01600
gene id: 335541:SWOL_RS01600
uniprot id: Q0B048
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

335541:SWOL RS08335
gene id: 335541:SWOL_RS08335
uniprot id: Q0AWJ2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

335541:SWOL RS09135
gene id: 335541:SWOL_RS09135
uniprot id: Q0AW42
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

335541:SWOL RS01350
gene id: 335541:SWOL_RS01350
uniprot id: Q0B095
names: Similarity
messages: Belongs to the PGI/PMI family.

335541:SWOL RS05900
gene id: 335541:SWOL_RS05900
uniprot id: Q0AXU2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

335541:SWOL RS06525
gene id: 335541:SWOL_RS06525
uniprot id: Q0AXH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

335541:SWOL RS06870
gene id: 335541:SWOL_RS06870
uniprot id: Q0AXB9
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS13270
gene id: 335541:SWOL_RS13270
uniprot id: Q0ATV0
names: Similarity
messages: Belongs to the ParB family.

335541:SWOL RS01455
gene id: 335541:SWOL_RS01455
uniprot id: Q0B075
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

335541:SWOL RS02965
gene id: 335541:SWOL_RS02965
uniprot id: Q0AZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

335541:SWOL RS07640
gene id: 335541:SWOL_RS07640
uniprot id: Q0AWX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

335541:SWOL RS10430
gene id: 335541:SWOL_RS10430
uniprot id: Q0AVE3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

335541:SWOL RS05565
gene id: 335541:SWOL_RS05565
uniprot id: Q0AY02
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

335541:SWOL RS13430
gene id: 335541:SWOL_RS13430
uniprot id: Q0B019
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

335541:SWOL RS09265
gene id: 335541:SWOL_RS09265
uniprot id: Q0AW15
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

335541:SWOL RS08320
gene id: 335541:SWOL_RS08320
uniprot id: Q0AWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

335541:SWOL RS02485
gene id: 335541:SWOL_RS02485
uniprot id: Q0AZM9
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

335541:SWOL RS07395
gene id: 335541:SWOL_RS07395
uniprot id: Q0AX17
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

335541:SWOL RS11195
gene id: 335541:SWOL_RS11195
uniprot id: Q0AUZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArsB family.
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04030
gene id: 335541:SWOL_RS04030
uniprot id: Q0AYT5
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

335541:SWOL RS01910
gene id: 335541:SWOL_RS01910
uniprot id: Q0AZZ1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

335541:SWOL RS00050
gene id: 335541:SWOL_RS00050
uniprot id: Q0B0Y7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

335541:SWOL RS08635
gene id: 335541:SWOL_RS08635
uniprot id: Q0AWD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

335541:SWOL RS00195
gene id: 335541:SWOL_RS00195
uniprot id: Q0B0W3
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

335541:SWOL RS08255
gene id: 335541:SWOL_RS08255
uniprot id: Q0AWK7
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS03440
gene id: 335541:SWOL_RS03440
uniprot id: Q0AZ47
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

335541:SWOL RS00640
gene id: 335541:SWOL_RS00640
uniprot id: Q0B0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

335541:SWOL RS02310
gene id: 335541:SWOL_RS02310
uniprot id: Q0AZR5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

335541:SWOL RS08850
gene id: 335541:SWOL_RS08850
uniprot id: Q0AW93
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

335541:SWOL RS01435
gene id: 335541:SWOL_RS01435
uniprot id: Q0B079
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

335541:SWOL RS03915
gene id: 335541:SWOL_RS03915
uniprot id: Q0AYV8
names: Caution
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS08295
gene id: 335541:SWOL_RS08295
uniprot id: Q0AWK0
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

335541:SWOL RS04210
gene id: 335541:SWOL_RS04210
uniprot id: Q0AYQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U4 family.
messages: Cell membrane
messages: Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.

335541:SWOL RS09920
gene id: 335541:SWOL_RS09920
uniprot id: Q0AVN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

335541:SWOL RS08020
gene id: 335541:SWOL_RS08020
uniprot id: Q0AWQ3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

335541:SWOL RS08965
gene id: 335541:SWOL_RS08965
uniprot id: Q0AW69
names: Similarity
messages: Belongs to the ABC transporter superfamily.

335541:SWOL RS01935
gene id: 335541:SWOL_RS01935
uniprot id: Q0AZY6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

335541:SWOL RS12440
gene id: 335541:SWOL_RS12440
uniprot id: Q0AUB5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS10970
gene id: 335541:SWOL_RS10970
uniprot id: Q0AV41
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

335541:SWOL RS08790
gene id: 335541:SWOL_RS08790
uniprot id: Q0AWA5
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335541:SWOL RS08500
gene id: 335541:SWOL_RS08500
uniprot id: Q0AWG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

335541:SWOL RS01695
gene id: 335541:SWOL_RS01695
uniprot id: Q0B029
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS03230
gene id: 335541:SWOL_RS03230
uniprot id: Q0AZ88
names: Similarity
messages: Belongs to the ThiD family.

335541:SWOL RS11090
gene id: 335541:SWOL_RS11090
uniprot id: Q0AV18
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

335541:SWOL RS12010
gene id: 335541:SWOL_RS12010
uniprot id: Q0AUJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

335541:SWOL RS05320
gene id: 335541:SWOL_RS05320
uniprot id: Q0AY43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

335541:SWOL RS07745
gene id: 335541:SWOL_RS07745
uniprot id: Q0AWV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

335541:SWOL RS01890
gene id: 335541:SWOL_RS01890
uniprot id: Q0AZZ5
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

335541:SWOL RS04820
gene id: 335541:SWOL_RS04820
uniprot id: Q0AYE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

335541:SWOL RS02060
gene id: 335541:SWOL_RS02060
uniprot id: Q0AZW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS12030
gene id: 335541:SWOL_RS12030
uniprot id: Q0AUJ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

335541:SWOL RS01075
gene id: 335541:SWOL_RS01075
uniprot id: Q0B0E9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

335541:SWOL RS09090
gene id: 335541:SWOL_RS09090
uniprot id: Q0AW50
names: Similarity
messages: Belongs to the CRISPR-associated Cas10/Csm1 family.

335541:SWOL RS10555
gene id: 335541:SWOL_RS10555
uniprot id: Q0AVC0
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

335541:SWOL RS09930
gene id: 335541:SWOL_RS09930
uniprot id: Q0AVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

335541:SWOL RS12760
gene id: 335541:SWOL_RS12760
uniprot id: Q0AU51
names: Similarity
messages: Belongs to the UPF0145 family.

335541:SWOL RS13440
gene id: 335541:SWOL_RS13440
uniprot id: Q0AZZ9
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

335541:SWOL RS09730
gene id: 335541:SWOL_RS09730
uniprot id: Q0AVS4
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

335541:SWOL RS09325
gene id: 335541:SWOL_RS09325
uniprot id: Q0AW03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

335541:SWOL RS06860
gene id: 335541:SWOL_RS06860
uniprot id: Q0AXC1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

335541:SWOL RS03905
gene id: 335541:SWOL_RS03905
uniprot id: Q0AYW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

335541:SWOL RS03105
gene id: 335541:SWOL_RS03105
uniprot id: Q0AZB2
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.
messages: In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.

335541:SWOL RS06080
gene id: 335541:SWOL_RS06080
uniprot id: Q0AXR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

335541:SWOL RS08510
gene id: 335541:SWOL_RS08510
uniprot id: Q0AWF8
names: Similarity
messages: Belongs to the UPF0111 family.

335541:SWOL RS02435
gene id: 335541:SWOL_RS02435
uniprot id: Q0AZN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

335541:SWOL RS03975
gene id: 335541:SWOL_RS03975
uniprot id: Q0AYU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

335541:SWOL RS08855
gene id: 335541:SWOL_RS08855
uniprot id: Q0AW92
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS08555
gene id: 335541:SWOL_RS08555
uniprot id: Q0AWF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

335541:SWOL RS04235
gene id: 335541:SWOL_RS04235
uniprot id: Q0AYP6
names: Similarity
messages: Belongs to the DprA/Smf family.

335541:SWOL RS03895
gene id: 335541:SWOL_RS03895
uniprot id: Q0AYW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

335541:SWOL RS01640
gene id: 335541:SWOL_RS01640
uniprot id: Q0B041
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS12775
gene id: 335541:SWOL_RS12775
uniprot id: Q0AU48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

335541:SWOL RS12600
gene id: 335541:SWOL_RS12600
uniprot id: Q0AU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

335541:SWOL RS09155
gene id: 335541:SWOL_RS09155
uniprot id: Q0AW38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

335541:SWOL RS02370
gene id: 335541:SWOL_RS02370
uniprot id: Q0AZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

335541:SWOL RS08445
gene id: 335541:SWOL_RS08445
uniprot id: Q0AWH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

335541:SWOL RS08250
gene id: 335541:SWOL_RS08250
uniprot id: Q0AWK8
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

335541:SWOL RS03235
gene id: 335541:SWOL_RS03235
uniprot id: Q0AZ87
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

335541:SWOL RS11985
gene id: 335541:SWOL_RS11985
uniprot id: Q0AUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

335541:SWOL RS08345
gene id: 335541:SWOL_RS08345
uniprot id: Q0AWJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

335541:SWOL RS09290
gene id: 335541:SWOL_RS09290
uniprot id: Q0AW11
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

335541:SWOL RS03170
gene id: 335541:SWOL_RS03170
uniprot id: Q0AZ99
names: Subcellular Location Annotation
messages: Cell membrane

335541:SWOL RS08550
gene id: 335541:SWOL_RS08550
uniprot id: Q0AWF1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

335541:SWOL RS06710
gene id: 335541:SWOL_RS06710
uniprot id: Q0AXE5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

335541:SWOL RS06815
gene id: 335541:SWOL_RS06815
uniprot id: Q0AXC9
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.

335541:SWOL RS04180
gene id: 335541:SWOL_RS04180
uniprot id: Q0AYQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS09715
gene id: 335541:SWOL_RS09715
uniprot id: Q0AVS7
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

335541:SWOL RS13350
gene id: 335541:SWOL_RS13350
uniprot id: Q0B0M4
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

335541:SWOL RS02710
gene id: 335541:SWOL_RS02710
uniprot id: Q0AZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

335541:SWOL RS06485
gene id: 335541:SWOL_RS06485
uniprot id: Q0AXI3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

335541:SWOL RS13495
gene id: 335541:SWOL_RS13495
uniprot id: Q0AYP7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

335541:SWOL RS06570
gene id: 335541:SWOL_RS06570
uniprot id: Q0AXG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

335541:SWOL RS06505
gene id: 335541:SWOL_RS06505
uniprot id: Q0AXH9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane

335541:SWOL RS00960
gene id: 335541:SWOL_RS00960
uniprot id: Q0B0H1
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS07720
gene id: 335541:SWOL_RS07720
uniprot id: Q0AWW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

335541:SWOL RS06825
gene id: 335541:SWOL_RS06825
uniprot id: Q0AXC7
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

335541:SWOL RS06875
gene id: 335541:SWOL_RS06875
uniprot id: Q0AXB8
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS09785
gene id: 335541:SWOL_RS09785
uniprot id: Q0AVR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS04390
gene id: 335541:SWOL_RS04390
uniprot id: Q0AYL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

335541:SWOL RS08960
gene id: 335541:SWOL_RS08960
uniprot id: Q0AW70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS03325
gene id: 335541:SWOL_RS03325
uniprot id: Q0AZ70
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335541:SWOL RS07750
gene id: 335541:SWOL_RS07750
uniprot id: Q0AWV4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

335541:SWOL RS01410
gene id: 335541:SWOL_RS01410
uniprot id: Q0B084
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

335541:SWOL RS00160
gene id: 335541:SWOL_RS00160
uniprot id: Q0B0X0
names: Similarity
messages: Belongs to the thioesterase PaaI family.

335541:SWOL RS08515
gene id: 335541:SWOL_RS08515
uniprot id: Q0AWF7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

335541:SWOL RS02885
gene id: 335541:SWOL_RS02885
uniprot id: Q0AZF2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

335541:SWOL RS04375
gene id: 335541:SWOL_RS04375
uniprot id: Q0AYL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

335541:SWOL RS02630
gene id: 335541:SWOL_RS02630
uniprot id: Q0AZK1
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

335541:SWOL RS09145
gene id: 335541:SWOL_RS09145
uniprot id: Q0AW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

335541:SWOL RS08450
gene id: 335541:SWOL_RS08450
uniprot id: Q0AWH0
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

335541:SWOL RS11390
gene id: 335541:SWOL_RS11390
uniprot id: Q0AUU4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

335541:SWOL RS07880
gene id: 335541:SWOL_RS07880
uniprot id: Q0AWT0
names: Similarity
messages: Belongs to the cytochrome c-552 family.

335541:SWOL RS08690
gene id: 335541:SWOL_RS08690
uniprot id: Q0AWC5
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS11995
gene id: 335541:SWOL_RS11995
uniprot id: Q0AUJ8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

335541:SWOL RS10415
gene id: 335541:SWOL_RS10415
uniprot id: Q0AVE6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

335541:SWOL RS12310
gene id: 335541:SWOL_RS12310
uniprot id: Q0AUE1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS05205
gene id: 335541:SWOL_RS05205
uniprot id: Q0AY65
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335541:SWOL RS10215
gene id: 335541:SWOL_RS10215
uniprot id: Q0AVI1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

335541:SWOL RS10305
gene id: 335541:SWOL_RS10305
uniprot id: Q0AVG4
names: Similarity
messages: Belongs to the UPF0047 family.

335541:SWOL RS12355
gene id: 335541:SWOL_RS12355
uniprot id: Q0AUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

335541:SWOL RS04685
gene id: 335541:SWOL_RS04685
uniprot id: Q0AYF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS04370
gene id: 335541:SWOL_RS04370
uniprot id: Q0AYM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

335541:SWOL RS11470
gene id: 335541:SWOL_RS11470
uniprot id: Q0AUU4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

335541:SWOL RS12525
gene id: 335541:SWOL_RS12525
uniprot id: Q0AU97
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

335541:SWOL RS00705
gene id: 335541:SWOL_RS00705
uniprot id: Q0B0L9
names: Similarity
messages: Belongs to the peptidase S8 family.

335541:SWOL RS04540
gene id: 335541:SWOL_RS04540
uniprot id: Q0AYI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

335541:SWOL RS02380
gene id: 335541:SWOL_RS02380
uniprot id: Q0AZQ0
names: Similarity
messages: Belongs to the UPF0297 family.

335541:SWOL RS08275
gene id: 335541:SWOL_RS08275
uniprot id: Q0AWK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

335541:SWOL RS13120
gene id: 335541:SWOL_RS13120
uniprot id: Q0ATX7
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

335541:SWOL RS06715
gene id: 335541:SWOL_RS06715
uniprot id: Q0AXE4
names: Similarity
messages: Belongs to the threonine synthase family.

335541:SWOL RS10065
gene id: 335541:SWOL_RS10065
uniprot id: Q0AVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

335541:SWOL RS01840
gene id: 335541:SWOL_RS01840
uniprot id: Q0B005
names: Similarity
messages: Belongs to the TrpC family.

335541:SWOL RS11965
gene id: 335541:SWOL_RS11965
uniprot id: Q0AUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

335541:SWOL RS09700
gene id: 335541:SWOL_RS09700
uniprot id: Q0AVT0
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

335541:SWOL RS09195
gene id: 335541:SWOL_RS09195
uniprot id: Q0AW30
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

335541:SWOL RS04580
gene id: 335541:SWOL_RS04580
uniprot id: Q0AYH9
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

335541:SWOL RS03305
gene id: 335541:SWOL_RS03305
uniprot id: Q0AZ74
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

335541:SWOL RS04425
gene id: 335541:SWOL_RS04425
uniprot id: Q0AYK9
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

335541:SWOL RS09625
gene id: 335541:SWOL_RS09625
uniprot id: Q0AVU3
names: Similarity
messages: Belongs to the band 7/mec-2 family.

335541:SWOL RS12075
gene id: 335541:SWOL_RS12075
uniprot id: Q0AUI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

335541:SWOL RS12380
gene id: 335541:SWOL_RS12380
uniprot id: Q0AUC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

335541:SWOL RS04045
gene id: 335541:SWOL_RS04045
uniprot id: Q0AYT2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

335541:SWOL RS13685
gene id: 335541:SWOL_RS13685
uniprot id: Q0AVN8
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

335541:SWOL RS00690
gene id: 335541:SWOL_RS00690
uniprot id: Q0B0M2
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS12735
gene id: 335541:SWOL_RS12735
uniprot id: Q0AU56
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

335541:SWOL RS07815
gene id: 335541:SWOL_RS07815
uniprot id: Q0AWU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

335541:SWOL RS03415
gene id: 335541:SWOL_RS03415
uniprot id: Q0AZ52
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335541:SWOL RS00150
gene id: 335541:SWOL_RS00150
uniprot id: Q0AUU4
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

335541:SWOL RS07840
gene id: 335541:SWOL_RS07840
uniprot id: Q0AWT9
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

335541:SWOL RS03085
gene id: 335541:SWOL_RS03085
uniprot id: Q0AZB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

335541:SWOL RS02870
gene id: 335541:SWOL_RS02870
uniprot id: Q0AZF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

335541:SWOL RS02080
gene id: 335541:SWOL_RS02080
uniprot id: Q0AZV8
names: Similarity
messages: Belongs to the NifH/BchL/ChlL family.

335541:SWOL RS12240
gene id: 335541:SWOL_RS12240
uniprot id: Q0AUF5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

335541:SWOL RS03665
gene id: 335541:SWOL_RS03665
uniprot id: Q0AZ05
names: Similarity
messages: Belongs to the polysaccharide synthase family.

335541:SWOL RS08165
gene id: 335541:SWOL_RS08165
uniprot id: Q0AWM4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

335541:SWOL RS10005
gene id: 335541:SWOL_RS10005
uniprot id: Q0AVM1
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Cytoplasm
messages: Highly expressed during syntrophic growth with butyrate (at protein level). Seems to be constitutively expressed.
messages: Homotetramer.
messages: Involved in syntrophic growth of S.wolfei with butyrate, as part of the butyrate oxidation pathway. Probably catalyzes the hydration of crotonyl-CoA to 3-hydroxybutyryl-CoA.

335541:SWOL RS00425
gene id: 335541:SWOL_RS00425
uniprot id: Q0B0S6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

335541:SWOL RS08185
gene id: 335541:SWOL_RS08185
uniprot id: Q0AWM1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

335541:SWOL RS10975
gene id: 335541:SWOL_RS10975
uniprot id: Q0AV40
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

335541:SWOL RS11150
gene id: 335541:SWOL_RS11150
uniprot id: Q0AV06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

335541:SWOL RS06580
gene id: 335541:SWOL_RS06580
uniprot id: Q0AXG5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Heterotetramer of 2 PyrK and 2 PyrD type B subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).

335541:SWOL RS04555
gene id: 335541:SWOL_RS04555
uniprot id: Q0AYI4
names: Similarity
messages: Belongs to the ribF family.

335541:SWOL RS09570
gene id: 335541:SWOL_RS09570
uniprot id: Q0AVV5
names: Similarity
messages: Belongs to the fabD family.

335541:SWOL RS03875
gene id: 335541:SWOL_RS03875
uniprot id: Q0AYW6
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

335541:SWOL RS09130
gene id: 335541:SWOL_RS09130
uniprot id: Q0AW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

335541:SWOL RS04850
gene id: 335541:SWOL_RS04850
uniprot id: Q0AYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

335541:SWOL RS00475
gene id: 335541:SWOL_RS00475
uniprot id: Q0B0R6
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS01995
gene id: 335541:SWOL_RS01995
uniprot id: Q0AZX4
names: Similarity
messages: Belongs to the YoeB family.

335541:SWOL RS03520
gene id: 335541:SWOL_RS03520
uniprot id: Q0AZ33
names: Cofactor
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Heterodimer of an alpha and a beta subunit.
messages: Highly expressed during syntrophic growth with butyrate (at protein level) (PubMed:19648244, PubMed:23468890). Seems to be constitutively expressed (PubMed:23468890).
messages: Part of an electron transfer flavoprotein involved in syntrophic growth of S.wolfei with butyrate. Probably receives electrons from butyryl-CoA dehydrogenases, and transfers them to the membrane-bound quinone oxidoreductase Swol_0698.

335541:SWOL RS04095
gene id: 335541:SWOL_RS04095
uniprot id: Q0AYS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS10420
gene id: 335541:SWOL_RS10420
uniprot id: Q0AVE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

335541:SWOL RS06615
gene id: 335541:SWOL_RS06615
uniprot id: Q0AXF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

335541:SWOL RS00025
gene id: 335541:SWOL_RS00025
uniprot id: Q0B0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

335541:SWOL RS12020
gene id: 335541:SWOL_RS12020
uniprot id: Q0AUJ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

335541:SWOL RS04845
gene id: 335541:SWOL_RS04845
uniprot id: Q0AYD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

335541:SWOL RS02505
gene id: 335541:SWOL_RS02505
uniprot id: Q0AZM5
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

335541:SWOL RS05215
gene id: 335541:SWOL_RS05215
uniprot id: Q0AY63
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335541:SWOL RS03935
gene id: 335541:SWOL_RS03935
uniprot id: Q0AYV4
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

335541:SWOL RS06365
gene id: 335541:SWOL_RS06365
uniprot id: Q0AXK6
names: Similarity
messages: Belongs to the YicC/YloC family.

335541:SWOL RS02960
gene id: 335541:SWOL_RS02960
uniprot id: Q0AZE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

335541:SWOL RS08520
gene id: 335541:SWOL_RS08520
uniprot id: Q0AWF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

335541:SWOL RS05585
gene id: 335541:SWOL_RS05585
uniprot id: Q0AXZ8
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

335541:SWOL RS13010
gene id: 335541:SWOL_RS13010
uniprot id: Q0ATZ8
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

335541:SWOL RS12365
gene id: 335541:SWOL_RS12365
uniprot id: Q0AUD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

335541:SWOL RS02045
gene id: 335541:SWOL_RS02045
uniprot id: Q0AZW4
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

335541:SWOL RS04490
gene id: 335541:SWOL_RS04490
uniprot id: Q0AYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

335541:SWOL RS03505
gene id: 335541:SWOL_RS03505
uniprot id: Q0AZ36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS03840
gene id: 335541:SWOL_RS03840
uniprot id: Q0AYX1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination.
messages: Belongs to the peptidase A25 family.
messages: Homotetramer.
messages: Initiates the rapid degradation of small, acid-soluble proteins during spore germination.

335541:SWOL RS00105
gene id: 335541:SWOL_RS00105
uniprot id: Q0B0Y0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

335541:SWOL RS01725
gene id: 335541:SWOL_RS01725
uniprot id: Q0B023
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS08795
gene id: 335541:SWOL_RS08795
uniprot id: Q0AWA4
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

335541:SWOL RS03060
gene id: 335541:SWOL_RS03060
uniprot id: Q0AZC1
names: Similarity
messages: Belongs to the HepT RNase toxin family.

335541:SWOL RS13300
gene id: 335541:SWOL_RS13300
uniprot id: Q0ATU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

335541:SWOL RS03890
gene id: 335541:SWOL_RS03890
uniprot id: Q0AYW3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

335541:SWOL RS12135
gene id: 335541:SWOL_RS12135
uniprot id: Q0AUH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

335541:SWOL RS09630
gene id: 335541:SWOL_RS09630
uniprot id: Q0AVU2
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

335541:SWOL RS04865
gene id: 335541:SWOL_RS04865
uniprot id: Q0AYD1
names: Subcellular Location Annotation
messages: Cytoplasm

335541:SWOL RS07740
gene id: 335541:SWOL_RS07740
uniprot id: Q0AWV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

335541:SWOL RS09805
gene id: 335541:SWOL_RS09805
uniprot id: Q0AVQ9
names: Similarity
messages: Belongs to the DEAD box helicase family.

335541:SWOL RS06360
gene id: 335541:SWOL_RS06360
uniprot id: Q0AXK7
names: Similarity
messages: Belongs to the RemA family.

335541:SWOL RS04935
gene id: 335541:SWOL_RS04935
uniprot id: Q0AYB8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

335541:SWOL RS08315
gene id: 335541:SWOL_RS08315
uniprot id: Q0AWJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

335541:SWOL RS10810
gene id: 335541:SWOL_RS10810
uniprot id: Q0AV73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

335541:SWOL RS06585
gene id: 335541:SWOL_RS06585
uniprot id: Q0AXG4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS04505
gene id: 335541:SWOL_RS04505
uniprot id: Q0AYJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

335541:SWOL RS04750
gene id: 335541:SWOL_RS04750
uniprot id: Q0AYF4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335541:SWOL RS05200
gene id: 335541:SWOL_RS05200
uniprot id: Q0AY66
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335541:SWOL RS03250
gene id: 335541:SWOL_RS03250
uniprot id: Q0AZ84
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

335541:SWOL RS04255
gene id: 335541:SWOL_RS04255
uniprot id: Q0AYP2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

335541:SWOL RS03925
gene id: 335541:SWOL_RS03925
uniprot id: Q0AYV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

335541:SWOL RS12005
gene id: 335541:SWOL_RS12005
uniprot id: Q0AUJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

335541:SWOL RS04050
gene id: 335541:SWOL_RS04050
uniprot id: Q0AYT1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

335541:SWOL RS13090
gene id: 335541:SWOL_RS13090
uniprot id: Q0ATY3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

335541:SWOL RS04270
gene id: 335541:SWOL_RS04270
uniprot id: Q0AYN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

335541:SWOL RS10435
gene id: 335541:SWOL_RS10435
uniprot id: Q0AVE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

335541:SWOL RS03930
gene id: 335541:SWOL_RS03930
uniprot id: Q0AYV5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

335541:SWOL RS02955
gene id: 335541:SWOL_RS02955
uniprot id: Q0AZE1
names: Similarity
messages: Belongs to the TlyA family.

335541:SWOL RS05285
gene id: 335541:SWOL_RS05285
uniprot id: Q0AY50
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS03275
gene id: 335541:SWOL_RS03275
uniprot id: Q0AZ79
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

335541:SWOL RS05555
gene id: 335541:SWOL_RS05555
uniprot id: Q0AY04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

335541:SWOL RS04560
gene id: 335541:SWOL_RS04560
uniprot id: Q0AYI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

335541:SWOL RS12410
gene id: 335541:SWOL_RS12410
uniprot id: Q0AUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

335541:SWOL RS11910
gene id: 335541:SWOL_RS11910
uniprot id: Q0AUL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

335541:SWOL RS06110
gene id: 335541:SWOL_RS06110
uniprot id: Q0AXQ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

335541:SWOL RS13750
gene id: 335541:SWOL_RS13750
uniprot id: Q0AV56
names: Function
messages: May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.

335541:SWOL RS07385
gene id: 335541:SWOL_RS07385
uniprot id: Q0AX19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

335541:SWOL RS00445
gene id: 335541:SWOL_RS00445
uniprot id: Q0B0S2
names: Similarity
messages: Belongs to the GerABKC lipoprotein family.

335541:SWOL RS12505
gene id: 335541:SWOL_RS12505
uniprot id: Q0AUA2
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS02150
gene id: 335541:SWOL_RS02150
uniprot id: Q0AZU5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

335541:SWOL RS04885
gene id: 335541:SWOL_RS04885
uniprot id: Q0AYC7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

335541:SWOL RS08800
gene id: 335541:SWOL_RS08800
uniprot id: Q0AWA3
names: Similarity
messages: Belongs to the AOR/FOR family.

335541:SWOL RS02755
gene id: 335541:SWOL_RS02755
uniprot id: Q0AZH8
names: Similarity
messages: Belongs to the peptidase U62 family.

335541:SWOL RS01430
gene id: 335541:SWOL_RS01430
uniprot id: Q0B080
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

335541:SWOL RS10240
gene id: 335541:SWOL_RS10240
uniprot id: Q0AVH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

335541:SWOL RS04775
gene id: 335541:SWOL_RS04775
uniprot id: Q0AYE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the diaminopimelate dehydrogenase family.
messages: Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.
messages: Homodimer.

335541:SWOL RS08540
gene id: 335541:SWOL_RS08540
uniprot id: Q0AWF3
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

335541:SWOL RS06325
gene id: 335541:SWOL_RS06325
uniprot id: Q0AXL4
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

335541:SWOL RS00810
gene id: 335541:SWOL_RS00810
uniprot id: Q0B0K0
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

335541:SWOL RS05155
gene id: 335541:SWOL_RS05155
uniprot id: Q0AY75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

335541:SWOL RS01045
gene id: 335541:SWOL_RS01045
uniprot id: Q0B0F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

335541:SWOL RS07700
gene id: 335541:SWOL_RS07700
uniprot id: Q0AWW4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

335541:SWOL RS00605
gene id: 335541:SWOL_RS00605
uniprot id: Q0B0N9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS11680
gene id: 335541:SWOL_RS11680
uniprot id: Q0AUQ6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

335541:SWOL RS07435
gene id: 335541:SWOL_RS07435
uniprot id: Q0AX09
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

335541:SWOL RS06165
gene id: 335541:SWOL_RS06165
uniprot id: Q0AXP4
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

335541:SWOL RS11075
gene id: 335541:SWOL_RS11075
uniprot id: Q0AV21
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

335541:SWOL RS09075
gene id: 335541:SWOL_RS09075
uniprot id: Q0AW53
names: Similarity
messages: Belongs to the CRISPR-associated Csm4 family.

335541:SWOL RS06970
gene id: 335541:SWOL_RS06970
uniprot id: Q0AX99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

335541:SWOL RS03960
gene id: 335541:SWOL_RS03960
uniprot id: Q0AYU9
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

335541:SWOL RS05300
gene id: 335541:SWOL_RS05300
uniprot id: Q0AY47
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS12350
gene id: 335541:SWOL_RS12350
uniprot id: Q0AUD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

335541:SWOL RS08545
gene id: 335541:SWOL_RS08545
uniprot id: Q0AWF2
names: Similarity
messages: Belongs to the peptidase S16 family.

335541:SWOL RS04790
gene id: 335541:SWOL_RS04790
uniprot id: Q0AYE6
names: Subcellular Location Annotation
messages: Membrane

335541:SWOL RS07045
gene id: 335541:SWOL_RS07045
uniprot id: Q0AX85
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

335541:SWOL RS01845
gene id: 335541:SWOL_RS01845
uniprot id: Q0B004
names: Similarity
messages: Belongs to the TrpF family.

335541:SWOL RS03595
gene id: 335541:SWOL_RS03595
uniprot id: Q0AZ19
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

335541:SWOL RS09230
gene id: 335541:SWOL_RS09230
uniprot id: Q0AW22
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

335541:SWOL RS12490
gene id: 335541:SWOL_RS12490
uniprot id: Q0AUA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

335541:SWOL RS05260
gene id: 335541:SWOL_RS05260
uniprot id: Q0AVI1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

335541:SWOL RS00155
gene id: 335541:SWOL_RS00155
uniprot id: Q0AUU5
names: Similarity
messages: Belongs to the transposase IS21/IS408/IS1162 family.

335541:SWOL RS10570
gene id: 335541:SWOL_RS10570
uniprot id: Q0AVB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

335541:SWOL RS03015
gene id: 335541:SWOL_RS03015
uniprot id: Q0AZD0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

335541:SWOL RS01245
gene id: 335541:SWOL_RS01245
uniprot id: Q0B0B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

335541:SWOL RS03410
gene id: 335541:SWOL_RS03410
uniprot id: Q0AZ53
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

335541:SWOL RS03110
gene id: 335541:SWOL_RS03110
uniprot id: Q0AZB1
names: Function
names: Similarity
messages: Belongs to the anti-sigma-factor family.
messages: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.

335541:SWOL RS11950
gene id: 335541:SWOL_RS11950
uniprot id: Q0AUK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

335541:SWOL RS04405
gene id: 335541:SWOL_RS04405
uniprot id: Q0AYL3
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

335541:SWOL RS03150
gene id: 335541:SWOL_RS03150
uniprot id: Q0AZA3
names: Similarity
messages: Belongs to the glycosyltransferase 10 family.

335541:SWOL RS11225
gene id: 335541:SWOL_RS11225
uniprot id: Q0AUZ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

335541:SWOL RS12785
gene id: 335541:SWOL_RS12785
uniprot id: Q0AU46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS07755
gene id: 335541:SWOL_RS07755
uniprot id: Q0AWV3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

335541:SWOL RS01010
gene id: 335541:SWOL_RS01010
uniprot id: Q0B0G2
names: Similarity
messages: Belongs to the FlgM family.

335541:SWOL RS06465
gene id: 335541:SWOL_RS06465
uniprot id: Q0AXI7
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.

335541:SWOL RS07220
gene id: 335541:SWOL_RS07220
uniprot id: Q0AX53
names: Similarity
messages: Belongs to the UPF0047 family.

335541:SWOL RS06305
gene id: 335541:SWOL_RS06305
uniprot id: Q0AXL8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

335541:SWOL RS11175
gene id: 335541:SWOL_RS11175
uniprot id: Q0AV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

335541:SWOL RS12480
gene id: 335541:SWOL_RS12480
uniprot id: Q0AUA7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

335541:SWOL RS00045
gene id: 335541:SWOL_RS00045
uniprot id: Q0B0Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

335541:SWOL RS04340
gene id: 335541:SWOL_RS04340
uniprot id: Q0AYM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

335541:SWOL RS02215
gene id: 335541:SWOL_RS02215
uniprot id: Q0AZT4
names: Similarity
messages: Belongs to the YoeB family.

335541:SWOL RS03465
gene id: 335541:SWOL_RS03465
uniprot id: Q0AZ43
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

335541:SWOL RS04240
gene id: 335541:SWOL_RS04240
uniprot id: Q0AYP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

335541:SWOL RS04075
gene id: 335541:SWOL_RS04075
uniprot id: Q0AYS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

335541:SWOL RS12585
gene id: 335541:SWOL_RS12585
uniprot id: Q0AU86
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

335541:SWOL RS02950
gene id: 335541:SWOL_RS02950
uniprot id: Q0AZE2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

335541:SWOL RS05635
gene id: 335541:SWOL_RS05635
uniprot id: Q0AXY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

335541:SWOL RS03475
gene id: 335541:SWOL_RS03475
uniprot id: Q0AZ42
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

335541:SWOL RS07080
gene id: 335541:SWOL_RS07080
uniprot id: Q0AX78
names: Similarity
messages: Belongs to the GbsR family.

335541:SWOL RS00630
gene id: 335541:SWOL_RS00630
uniprot id: Q0B0N4
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

335541:SWOL RS05930
gene id: 335541:SWOL_RS05930
uniprot id: Q0AXT7
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

335541:SWOL RS04810
gene id: 335541:SWOL_RS04810
uniprot id: Q0AYE2
names: Similarity
messages: Belongs to the flagella basal body rod proteins family.

335541:SWOL RS09425
gene id: 335541:SWOL_RS09425
uniprot id: Q0AVY2
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

335541:SWOL RS06150
gene id: 335541:SWOL_RS06150
uniprot id: Q0AXP7
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

335541:SWOL RS07285
gene id: 335541:SWOL_RS07285
uniprot id: Q0AX39
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

335541:SWOL RS02295
gene id: 335541:SWOL_RS02295
uniprot id: Q0AZR8
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

335541:SWOL RS00575
gene id: 335541:SWOL_RS00575
uniprot id: Q0B0P5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.