33037:I6H45 RS02550
gene id: 33037:I6H45_RS02550
uniprot id: A0A7T4F1V5
names: Cofactor
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

33037:I6H45 RS04550
gene id: 33037:I6H45_RS04550
uniprot id: A0A7T4F2I9
names: Similarity
messages: Belongs to the UPF0473 family.

33037:I6H45 RS05740
gene id: 33037:I6H45_RS05740
uniprot id: A0A7T4EZT1
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05570
gene id: 33037:I6H45_RS05570
uniprot id: A0A7T4EZN4
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

33037:I6H45 RS00365
gene id: 33037:I6H45_RS00365
uniprot id: A0A7T4F1C8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

33037:I6H45 RS06770
gene id: 33037:I6H45_RS06770
uniprot id: A0A6N2UKP5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

33037:I6H45 RS08790
gene id: 33037:I6H45_RS08790
uniprot id: A0A7T4K579
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS01485
gene id: 33037:I6H45_RS01485
uniprot id: A0A6N2RGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

33037:I6H45 RS04445
gene id: 33037:I6H45_RS04445
uniprot id: A0A7T4F2G7
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

33037:I6H45 RS06025
gene id: 33037:I6H45_RS06025
uniprot id: A0A7T4F0A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS01570
gene id: 33037:I6H45_RS01570
uniprot id: A0A7T4F1G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

33037:I6H45 RS05050
gene id: 33037:I6H45_RS05050
uniprot id: A0A7T4K4P6
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

33037:I6H45 RS02245
gene id: 33037:I6H45_RS02245
uniprot id: A0A7T4F1M4
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS01430
gene id: 33037:I6H45_RS01430
uniprot id: A0A6N2RDZ0
names: Similarity
messages: Belongs to the asp23 family.

33037:I6H45 RS03105
gene id: 33037:I6H45_RS03105
uniprot id: A0A7T4F2C5
names: Similarity
messages: Belongs to the type IA topoisomerase family.

33037:I6H45 RS02760
gene id: 33037:I6H45_RS02760
uniprot id: A0A7T4F1U2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS04460
gene id: 33037:I6H45_RS04460
uniprot id: A0A7T4F2H9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

33037:I6H45 RS07535
gene id: 33037:I6H45_RS07535
uniprot id: A0A7T4K4Y9
names: Similarity
messages: Belongs to the DapA family.

33037:I6H45 RS01190
gene id: 33037:I6H45_RS01190
uniprot id: A0A7T4F189
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).
messages: Belongs to the FGGY kinase family.
messages: Homotetramer and homodimer (in equilibrium).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

33037:I6H45 RS01805
gene id: 33037:I6H45_RS01805
uniprot id: A0A6N2R806
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

33037:I6H45 RS06760
gene id: 33037:I6H45_RS06760
uniprot id: A0A7T4F0H5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

33037:I6H45 RS02265
gene id: 33037:I6H45_RS02265
uniprot id: A0A7T4K5J1
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

33037:I6H45 RS08410
gene id: 33037:I6H45_RS08410
uniprot id: A0A7T4K554
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS02120
gene id: 33037:I6H45_RS02120
uniprot id: A0A7T4F1M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

33037:I6H45 RS04680
gene id: 33037:I6H45_RS04680
uniprot id: A0A7T4K4P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS07030
gene id: 33037:I6H45_RS07030
uniprot id: A0A6N2UDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS07700
gene id: 33037:I6H45_RS07700
uniprot id: A0A7T4K4Z9
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

33037:I6H45 RS06780
gene id: 33037:I6H45_RS06780
uniprot id: A0A6N2UGX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

33037:I6H45 RS02605
gene id: 33037:I6H45_RS02605
uniprot id: A0A7T4F283
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

33037:I6H45 RS05880
gene id: 33037:I6H45_RS05880
uniprot id: A0A7T4EZR7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

33037:I6H45 RS03685
gene id: 33037:I6H45_RS03685
uniprot id: A0A7T4K5T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

33037:I6H45 RS05995
gene id: 33037:I6H45_RS05995
uniprot id: A0A7T4K4Q8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

33037:I6H45 RS06735
gene id: 33037:I6H45_RS06735
uniprot id: A0A7T4K4S3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

33037:I6H45 RS03725
gene id: 33037:I6H45_RS03725
uniprot id: A0A7T4F259
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

33037:I6H45 RS02600
gene id: 33037:I6H45_RS02600
uniprot id: A0A7T4F1U0
names: Similarity
messages: Belongs to the GSP E family.

33037:I6H45 RS02345
gene id: 33037:I6H45_RS02345
uniprot id: A0A7T4K5W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

33037:I6H45 RS06280
gene id: 33037:I6H45_RS06280
uniprot id: A0A7T4F048
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

33037:I6H45 RS04065
gene id: 33037:I6H45_RS04065
uniprot id: A0A7T4K603
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07810
gene id: 33037:I6H45_RS07810
uniprot id: A0A7T4F0N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS01700
gene id: 33037:I6H45_RS01700
uniprot id: A0A6N2R9J0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

33037:I6H45 RS03170
gene id: 33037:I6H45_RS03170
uniprot id: A0A6N2SV63
names: Similarity
messages: Belongs to the DtxR/MntR family.

33037:I6H45 RS05220
gene id: 33037:I6H45_RS05220
uniprot id: A0A7T4K4K1
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

33037:I6H45 RS05585
gene id: 33037:I6H45_RS05585
uniprot id: A0A7T4EZR3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

33037:I6H45 RS08935
gene id: 33037:I6H45_RS08935
uniprot id: A0A7T4K569
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

33037:I6H45 RS02555
gene id: 33037:I6H45_RS02555
uniprot id: A0A7T4F1Z8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07140
gene id: 33037:I6H45_RS07140
uniprot id: A0A7T4K4W6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

33037:I6H45 RS00815
gene id: 33037:I6H45_RS00815
uniprot id: A0A7T4F166
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02755
gene id: 33037:I6H45_RS02755
uniprot id: A0A6N2TTI6
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

33037:I6H45 RS01125
gene id: 33037:I6H45_RS01125
uniprot id: A0A7T4F1C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

33037:I6H45 RS05310
gene id: 33037:I6H45_RS05310
uniprot id: A0A7T4F013
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

33037:I6H45 RS06740
gene id: 33037:I6H45_RS06740
uniprot id: A0A7T4K531
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

33037:I6H45 RS08220
gene id: 33037:I6H45_RS08220
uniprot id: A0A7T4F0U0
names: Similarity
messages: Belongs to the peptidase C1 family.

33037:I6H45 RS08420
gene id: 33037:I6H45_RS08420
uniprot id: A0A6N2TFE8
names: Similarity
messages: Belongs to the phD/YefM antitoxin family.

33037:I6H45 RS01955
gene id: 33037:I6H45_RS01955
uniprot id: A0A7T4K5T8
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.
messages: May be involved in the biosynthesis of molybdopterin.

33037:I6H45 RS06145
gene id: 33037:I6H45_RS06145
uniprot id: A0A6N2QYW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

33037:I6H45 RS01690
gene id: 33037:I6H45_RS01690
uniprot id: A0A6N2RAB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

33037:I6H45 RS00710
gene id: 33037:I6H45_RS00710
uniprot id: A0A7T4K5D3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS00460
gene id: 33037:I6H45_RS00460
uniprot id: A0A6N2T276
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS00635
gene id: 33037:I6H45_RS00635
uniprot id: A0A7T4F1E6
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05380
gene id: 33037:I6H45_RS05380
uniprot id: A0A7T4EZQ2
names: Similarity
messages: Belongs to the asp23 family.

33037:I6H45 RS01005
gene id: 33037:I6H45_RS01005
uniprot id: A0A6N2S4T3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

33037:I6H45 RS08045
gene id: 33037:I6H45_RS08045
uniprot id: A0A7T4F0I7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS00120
gene id: 33037:I6H45_RS00120
uniprot id: A0A7T4F120
names: Similarity
messages: Belongs to the disproportionating enzyme family.

33037:I6H45 RS06175
gene id: 33037:I6H45_RS06175
uniprot id: A0A7T4F060
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

33037:I6H45 RS01305
gene id: 33037:I6H45_RS01305
uniprot id: A0A6N2RCE1
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07380
gene id: 33037:I6H45_RS07380
uniprot id: A0A7T4F0J5
names: Similarity
messages: Belongs to the glutamine synthetase family.

33037:I6H45 RS02280
gene id: 33037:I6H45_RS02280
uniprot id: A0A7T4F1Y4
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

33037:I6H45 RS06100
gene id: 33037:I6H45_RS06100
uniprot id: A0A7T4F0B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

33037:I6H45 RS05225
gene id: 33037:I6H45_RS05225
uniprot id: A0A7T4EZT6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

33037:I6H45 RS05370
gene id: 33037:I6H45_RS05370
uniprot id: A0A7T4K4L3
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

33037:I6H45 RS06340
gene id: 33037:I6H45_RS06340
uniprot id: A0A7T4EZY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

33037:I6H45 RS06570
gene id: 33037:I6H45_RS06570
uniprot id: A0A6N2SW79
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

33037:I6H45 RS01785
gene id: 33037:I6H45_RS01785
uniprot id: A0A6N2R7L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

33037:I6H45 RS08870
gene id: 33037:I6H45_RS08870
uniprot id: A0A7T4K586
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS08850
gene id: 33037:I6H45_RS08850
uniprot id: A0A7T4K5E0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

33037:I6H45 RS02815
gene id: 33037:I6H45_RS02815
uniprot id: A0A7T4K5P0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07540
gene id: 33037:I6H45_RS07540
uniprot id: A0A7T4F0L5
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

33037:I6H45 RS01715
gene id: 33037:I6H45_RS01715
uniprot id: A0A6N2R9C4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

33037:I6H45 RS02090
gene id: 33037:I6H45_RS02090
uniprot id: A0A7T4K5R2
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

33037:I6H45 RS05175
gene id: 33037:I6H45_RS05175
uniprot id: A0A7T4EZI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

33037:I6H45 RS06005
gene id: 33037:I6H45_RS06005
uniprot id: A0A7T4K4Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

33037:I6H45 RS04740
gene id: 33037:I6H45_RS04740
uniprot id: A0A7T4K4M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm

33037:I6H45 RS08055
gene id: 33037:I6H45_RS08055
uniprot id: A0A7T4F0R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS06910
gene id: 33037:I6H45_RS06910
uniprot id: A0A7T4F0D6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

33037:I6H45 RS06520
gene id: 33037:I6H45_RS06520
uniprot id: A0A7T4F016
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

33037:I6H45 RS06575
gene id: 33037:I6H45_RS06575
uniprot id: A0A7T4F0A8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

33037:I6H45 RS05155
gene id: 33037:I6H45_RS05155
uniprot id: A0A6N2TYC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

33037:I6H45 RS06565
gene id: 33037:I6H45_RS06565
uniprot id: A0A7T4K527
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

33037:I6H45 RS04955
gene id: 33037:I6H45_RS04955
uniprot id: A0A6N2RQG2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

33037:I6H45 RS08090
gene id: 33037:I6H45_RS08090
uniprot id: A0A7T4K5B2
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS01870
gene id: 33037:I6H45_RS01870
uniprot id: A0A7T4K5G6
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

33037:I6H45 RS01310
gene id: 33037:I6H45_RS01310
uniprot id: A0A7T4K5H0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08485
gene id: 33037:I6H45_RS08485
uniprot id: A0A7T4K562
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS00485
gene id: 33037:I6H45_RS00485
uniprot id: A0A7T4F1G6
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06940
gene id: 33037:I6H45_RS06940
uniprot id: A0A7T4F0C1
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06850
gene id: 33037:I6H45_RS06850
uniprot id: A0A7T4F041
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

33037:I6H45 RS06475
gene id: 33037:I6H45_RS06475
uniprot id: A0A6N2QUW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

33037:I6H45 RS08925
gene id: 33037:I6H45_RS08925
uniprot id: A0A7T4F184
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

33037:I6H45 RS08810
gene id: 33037:I6H45_RS08810
uniprot id: A0A6N2S2P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

33037:I6H45 RS02070
gene id: 33037:I6H45_RS02070
uniprot id: A0A7T4F1P9
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08320
gene id: 33037:I6H45_RS08320
uniprot id: A0A7T4K525
names: Subcellular Location Annotation
messages: cell wall

33037:I6H45 RS02730
gene id: 33037:I6H45_RS02730
uniprot id: A0A7T4K5L9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

33037:I6H45 RS01815
gene id: 33037:I6H45_RS01815
uniprot id: A0A6N2R794
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

33037:I6H45 RS01330
gene id: 33037:I6H45_RS01330
uniprot id: A0A7T4K5F7
names: Similarity
messages: Belongs to the barstar family.

33037:I6H45 RS04375
gene id: 33037:I6H45_RS04375
uniprot id: A0A7T4F2H0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

33037:I6H45 RS01915
gene id: 33037:I6H45_RS01915
uniprot id: A0A7T4F1H7
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

33037:I6H45 RS07095
gene id: 33037:I6H45_RS07095
uniprot id: A0A7T4F072
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

33037:I6H45 RS01130
gene id: 33037:I6H45_RS01130
uniprot id: A0A7T4F1H1
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

33037:I6H45 RS02310
gene id: 33037:I6H45_RS02310
uniprot id: A0A7T4F1S8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS05085
gene id: 33037:I6H45_RS05085
uniprot id: A0A7T4EZX6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS08030
gene id: 33037:I6H45_RS08030
uniprot id: A0A7T4F0Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

33037:I6H45 RS06995
gene id: 33037:I6H45_RS06995
uniprot id: A0A6N2UG07
names: Similarity
messages: Belongs to the AlaDH/PNT family.

33037:I6H45 RS05135
gene id: 33037:I6H45_RS05135
uniprot id: A0A7T4K4I3
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

33037:I6H45 RS05400
gene id: 33037:I6H45_RS05400
uniprot id: A0A7T4EZL2
names: Similarity
messages: Belongs to the peptidase M24B family.

33037:I6H45 RS01940
gene id: 33037:I6H45_RS01940
uniprot id: A0A7T4K5Q3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

33037:I6H45 RS04800
gene id: 33037:I6H45_RS04800
uniprot id: A0A6N2UG46
names: Similarity
messages: Belongs to the UPF0297 family.

33037:I6H45 RS06545
gene id: 33037:I6H45_RS06545
uniprot id: A0A7T4F0E7
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS01810
gene id: 33037:I6H45_RS01810
uniprot id: A0A7T4F1T0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

33037:I6H45 RS00530
gene id: 33037:I6H45_RS00530
uniprot id: A0A7T4K5H2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

33037:I6H45 RS03335
gene id: 33037:I6H45_RS03335
uniprot id: A0A7T4F244
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08655
gene id: 33037:I6H45_RS08655
uniprot id: A0A7T4F0T3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

33037:I6H45 RS05890
gene id: 33037:I6H45_RS05890
uniprot id: A0A7T4F003
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

33037:I6H45 RS06030
gene id: 33037:I6H45_RS06030
uniprot id: A0A6N2QYG7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

33037:I6H45 RS02485
gene id: 33037:I6H45_RS02485
uniprot id: A0A7T4F1P7
names: Similarity
messages: Belongs to the UPF0246 family.

33037:I6H45 RS07200
gene id: 33037:I6H45_RS07200
uniprot id: A0A7T4F0L7
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

33037:I6H45 RS02625
gene id: 33037:I6H45_RS02625
uniprot id: A0A7T4F1W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

33037:I6H45 RS00345
gene id: 33037:I6H45_RS00345
uniprot id: A0A7T4F2I3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

33037:I6H45 RS04630
gene id: 33037:I6H45_RS04630
uniprot id: A0A7T4EZC4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

33037:I6H45 RS06110
gene id: 33037:I6H45_RS06110
uniprot id: A0A7T4EZU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

33037:I6H45 RS05195
gene id: 33037:I6H45_RS05195
uniprot id: A0A7T4EZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Could methylate the ribose at the nucleotide 34 wobble position in tRNA.
messages: Cytoplasm

33037:I6H45 RS08005
gene id: 33037:I6H45_RS08005
uniprot id: A0A7T4K505
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04360
gene id: 33037:I6H45_RS04360
uniprot id: A0A6N2U3T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

33037:I6H45 RS04920
gene id: 33037:I6H45_RS04920
uniprot id: A0A7T4K4I2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

33037:I6H45 RS05460
gene id: 33037:I6H45_RS05460
uniprot id: A0A7T4F032
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

33037:I6H45 RS08570
gene id: 33037:I6H45_RS08570
uniprot id: A0A6N2TGX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

33037:I6H45 RS05040
gene id: 33037:I6H45_RS05040
uniprot id: A0A7T4EZI9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

33037:I6H45 RS05780
gene id: 33037:I6H45_RS05780
uniprot id: A0A7T4EZV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS00170
gene id: 33037:I6H45_RS00170
uniprot id: A0A7T4F0Z6
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08085
gene id: 33037:I6H45_RS08085
uniprot id: A0A7T4K509
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

33037:I6H45 RS05425
gene id: 33037:I6H45_RS05425
uniprot id: A0A7T4K4S1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

33037:I6H45 RS03600
gene id: 33037:I6H45_RS03600
uniprot id: A0A7T4K5T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

33037:I6H45 RS01670
gene id: 33037:I6H45_RS01670
uniprot id: A0A6N2RCN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

33037:I6H45 RS07580
gene id: 33037:I6H45_RS07580
uniprot id: A0A7T4F0C8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08815
gene id: 33037:I6H45_RS08815
uniprot id: A0A6N2S0T5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

33037:I6H45 RS00830
gene id: 33037:I6H45_RS00830
uniprot id: A0A7T4F164
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

33037:I6H45 RS08545
gene id: 33037:I6H45_RS08545
uniprot id: A0A7T4K545
names: Similarity
names: Subunit
messages: Belongs to the methylthioribose kinase family.
messages: Homodimer.

33037:I6H45 RS03525
gene id: 33037:I6H45_RS03525
uniprot id: A0A7T4K5S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

33037:I6H45 RS02700
gene id: 33037:I6H45_RS02700
uniprot id: A0A7T4F1X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

33037:I6H45 RS06505
gene id: 33037:I6H45_RS06505
uniprot id: A0A7T4F031
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

33037:I6H45 RS06120
gene id: 33037:I6H45_RS06120
uniprot id: A0A7T4F030
names: Similarity
messages: Belongs to the IMPACT family.

33037:I6H45 RS01135
gene id: 33037:I6H45_RS01135
uniprot id: A0A7T4F182
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS01495
gene id: 33037:I6H45_RS01495
uniprot id: A0A7T4F1F5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

33037:I6H45 RS00445
gene id: 33037:I6H45_RS00445
uniprot id: A0A7T4K5G7
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.

33037:I6H45 RS00455
gene id: 33037:I6H45_RS00455
uniprot id: A0A7T4K585
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

33037:I6H45 RS07035
gene id: 33037:I6H45_RS07035
uniprot id: A0A7T4K517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05160
gene id: 33037:I6H45_RS05160
uniprot id: A0A7T4EZZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

33037:I6H45 RS07495
gene id: 33037:I6H45_RS07495
uniprot id: A0A7T4F0I3
names: Subcellular Location Annotation
messages: cell wall

33037:I6H45 RS01695
gene id: 33037:I6H45_RS01695
uniprot id: A0A6N2R8R4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

33037:I6H45 RS01020
gene id: 33037:I6H45_RS01020
uniprot id: A0A7T4F174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

33037:I6H45 RS01500
gene id: 33037:I6H45_RS01500
uniprot id: A0A7T4F1T2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

33037:I6H45 RS03260
gene id: 33037:I6H45_RS03260
uniprot id: A0A6N2SAK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02535
gene id: 33037:I6H45_RS02535
uniprot id: A0A7T4F1R5
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS01390
gene id: 33037:I6H45_RS01390
uniprot id: A0A6N2RDZ5
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

33037:I6H45 RS00275
gene id: 33037:I6H45_RS00275
uniprot id: A0A7T4F176
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.

33037:I6H45 RS00150
gene id: 33037:I6H45_RS00150
uniprot id: A0A7T4K567
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

33037:I6H45 RS05030
gene id: 33037:I6H45_RS05030
uniprot id: A0A7T4EZN8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04820
gene id: 33037:I6H45_RS04820
uniprot id: A0A7T4K4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
messages: Cytoplasm
messages: Homodimer, may be a subunit of the RNA degradosome.

33037:I6H45 RS06600
gene id: 33037:I6H45_RS06600
uniprot id: A0A7T4F025
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04665
gene id: 33037:I6H45_RS04665
uniprot id: A0A7T4K4M1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

33037:I6H45 RS06460
gene id: 33037:I6H45_RS06460
uniprot id: A0A7T4F001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

33037:I6H45 RS08510
gene id: 33037:I6H45_RS08510
uniprot id: A0A6N2TLH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05145
gene id: 33037:I6H45_RS05145
uniprot id: A0A7T4K4J8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04805
gene id: 33037:I6H45_RS04805
uniprot id: A0A7T4EZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

33037:I6H45 RS03465
gene id: 33037:I6H45_RS03465
uniprot id: A0A7T4F247
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

33037:I6H45 RS04905
gene id: 33037:I6H45_RS04905
uniprot id: A0A7T4K4G9
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

33037:I6H45 RS05105
gene id: 33037:I6H45_RS05105
uniprot id: A0A7T4EZP6
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

33037:I6H45 RS02080
gene id: 33037:I6H45_RS02080
uniprot id: A0A7T4F1K4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

33037:I6H45 RS03535
gene id: 33037:I6H45_RS03535
uniprot id: A0A7T4K5T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

33037:I6H45 RS05900
gene id: 33037:I6H45_RS05900
uniprot id: A0A7T4EZU6
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

33037:I6H45 RS07215
gene id: 33037:I6H45_RS07215
uniprot id: A0A6N2S926
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

33037:I6H45 RS07190
gene id: 33037:I6H45_RS07190
uniprot id: A0A7T4F0D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

33037:I6H45 RS05025
gene id: 33037:I6H45_RS05025
uniprot id: A0A7T4EZG4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04755
gene id: 33037:I6H45_RS04755
uniprot id: A0A6N2U6H2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

33037:I6H45 RS04515
gene id: 33037:I6H45_RS04515
uniprot id: A0A6N2U9F0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

33037:I6H45 RS05330
gene id: 33037:I6H45_RS05330
uniprot id: A0A7T4EZS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

33037:I6H45 RS08820
gene id: 33037:I6H45_RS08820
uniprot id: A0A7T4K614
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

33037:I6H45 RS05095
gene id: 33037:I6H45_RS05095
uniprot id: A0A7T4EZH7
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

33037:I6H45 RS07530
gene id: 33037:I6H45_RS07530
uniprot id: A0A7T4K581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

33037:I6H45 RS04845
gene id: 33037:I6H45_RS04845
uniprot id: A0A7T4EZN5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

33037:I6H45 RS05090
gene id: 33037:I6H45_RS05090
uniprot id: A0A7T4EZF5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

33037:I6H45 RS07240
gene id: 33037:I6H45_RS07240
uniprot id: A0A7T4F0P4
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04890
gene id: 33037:I6H45_RS04890
uniprot id: A0A6N2RT12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

33037:I6H45 RS06380
gene id: 33037:I6H45_RS06380
uniprot id: A0A7T4K4T2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

33037:I6H45 RS04055
gene id: 33037:I6H45_RS04055
uniprot id: A0A7T4F299
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

33037:I6H45 RS00495
gene id: 33037:I6H45_RS00495
uniprot id: A0A7T4F125
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

33037:I6H45 RS01730
gene id: 33037:I6H45_RS01730
uniprot id: A0A6N2RB25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

33037:I6H45 RS00235
gene id: 33037:I6H45_RS00235
uniprot id: A0A7T4K5A6
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

33037:I6H45 RS05805
gene id: 33037:I6H45_RS05805
uniprot id: A0A7T4F2I0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03505
gene id: 33037:I6H45_RS03505
uniprot id: A0A7T4F226
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

33037:I6H45 RS05855
gene id: 33037:I6H45_RS05855
uniprot id: A0A7T4K4P5
names: Similarity
messages: Belongs to the PRORSD1 family.

33037:I6H45 RS02380
gene id: 33037:I6H45_RS02380
uniprot id: A0A7T4F1N8
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

33037:I6H45 RS00200
gene id: 33037:I6H45_RS00200
uniprot id: A0A7T4F167
names: Similarity
messages: Belongs to the ClpA/ClpB family.

33037:I6H45 RS02325
gene id: 33037:I6H45_RS02325
uniprot id: A0A7T4F214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

33037:I6H45 RS06845
gene id: 33037:I6H45_RS06845
uniprot id: A0A7T4F045
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

33037:I6H45 RS02105
gene id: 33037:I6H45_RS02105
uniprot id: A0A7T4K5V1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

33037:I6H45 RS08610
gene id: 33037:I6H45_RS08610
uniprot id: A0A6N2TKC3
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

33037:I6H45 RS05280
gene id: 33037:I6H45_RS05280
uniprot id: A0A7T4K4L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

33037:I6H45 RS01895
gene id: 33037:I6H45_RS01895
uniprot id: A0A7T4F1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

33037:I6H45 RS03490
gene id: 33037:I6H45_RS03490
uniprot id: A0A7T4F263
names: Similarity
messages: Belongs to the CapA family.

33037:I6H45 RS08620
gene id: 33037:I6H45_RS08620
uniprot id: A0A7T4K553
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

33037:I6H45 RS01360
gene id: 33037:I6H45_RS01360
uniprot id: A0A7T4F1B2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

33037:I6H45 RS04660
gene id: 33037:I6H45_RS04660
uniprot id: A0A7T4F2G9
names: Similarity
messages: Belongs to the RecJ family.

33037:I6H45 RS08630
gene id: 33037:I6H45_RS08630
uniprot id: A0A7T4K5E6
names: Similarity
messages: Belongs to the FBPase class 2 family.

33037:I6H45 RS08015
gene id: 33037:I6H45_RS08015
uniprot id: A0A7T4K532
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04925
gene id: 33037:I6H45_RS04925
uniprot id: A0A7T4EZP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

33037:I6H45 RS06905
gene id: 33037:I6H45_RS06905
uniprot id: A0A7T4K4V2
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04745
gene id: 33037:I6H45_RS04745
uniprot id: A0A6N2UCQ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

33037:I6H45 RS04035
gene id: 33037:I6H45_RS04035
uniprot id: A0A7T4F2A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS00110
gene id: 33037:I6H45_RS00110
uniprot id: A0A6N2RZ33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS06800
gene id: 33037:I6H45_RS06800
uniprot id: A0A7T4K506
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

33037:I6H45 RS07655
gene id: 33037:I6H45_RS07655
uniprot id: A0A7T4F0E0
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

33037:I6H45 RS00535
gene id: 33037:I6H45_RS00535
uniprot id: A0A7T4K5A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

33037:I6H45 RS00360
gene id: 33037:I6H45_RS00360
uniprot id: A0A7T4F103
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

33037:I6H45 RS04280
gene id: 33037:I6H45_RS04280
uniprot id: A0A6N2U5R3
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

33037:I6H45 RS01830
gene id: 33037:I6H45_RS01830
uniprot id: A0A7T4F1H0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

33037:I6H45 RS01770
gene id: 33037:I6H45_RS01770
uniprot id: A0A6N2RAM4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

33037:I6H45 RS05680
gene id: 33037:I6H45_RS05680
uniprot id: A0A7T4K4N8
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

33037:I6H45 RS04355
gene id: 33037:I6H45_RS04355
uniprot id: A0A6N2U690
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

33037:I6H45 RS01230
gene id: 33037:I6H45_RS01230
uniprot id: A0A7T4K5G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02450
gene id: 33037:I6H45_RS02450
uniprot id: A0A7T4F264
names: Similarity
messages: Belongs to the GARS family.

33037:I6H45 RS04405
gene id: 33037:I6H45_RS04405
uniprot id: A0A7T4K5X3
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02715
gene id: 33037:I6H45_RS02715
uniprot id: A0A7T4F269
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

33037:I6H45 RS07965
gene id: 33037:I6H45_RS07965
uniprot id: A0A7T4F0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS01520
gene id: 33037:I6H45_RS01520
uniprot id: A0A7T4F1H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02630
gene id: 33037:I6H45_RS02630
uniprot id: A0A7T4F208
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

33037:I6H45 RS08275
gene id: 33037:I6H45_RS08275
uniprot id: A0A7T4F124
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

33037:I6H45 RS01920
gene id: 33037:I6H45_RS01920
uniprot id: A0A7T4F1N3
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

33037:I6H45 RS00790
gene id: 33037:I6H45_RS00790
uniprot id: A0A7T4F1G4
names: Similarity
messages: Belongs to the TelA family.

33037:I6H45 RS05015
gene id: 33037:I6H45_RS05015
uniprot id: A0A7T4EZE5
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

33037:I6H45 RS01735
gene id: 33037:I6H45_RS01735
uniprot id: A0A6N2RAF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

33037:I6H45 RS08205
gene id: 33037:I6H45_RS08205
uniprot id: A0A7T4K660
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

33037:I6H45 RS02220
gene id: 33037:I6H45_RS02220
uniprot id: A0A7T4F1M5
names: Similarity
messages: Belongs to the EamA transporter family.

33037:I6H45 RS07780
gene id: 33037:I6H45_RS07780
uniprot id: A0A7T4F0N9
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

33037:I6H45 RS05775
gene id: 33037:I6H45_RS05775
uniprot id: A0A7T4F017
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS01790
gene id: 33037:I6H45_RS01790
uniprot id: A0A6N2R8N2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

33037:I6H45 RS07475
gene id: 33037:I6H45_RS07475
uniprot id: A0A7T4F0C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

33037:I6H45 RS03255
gene id: 33037:I6H45_RS03255
uniprot id: A0A7T4F287
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06320
gene id: 33037:I6H45_RS06320
uniprot id: A0A7T4K4S5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

33037:I6H45 RS03435
gene id: 33037:I6H45_RS03435
uniprot id: A0A7T4K5Z1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

33037:I6H45 RS02750
gene id: 33037:I6H45_RS02750
uniprot id: A0A7T4F1W0
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

33037:I6H45 RS06055
gene id: 33037:I6H45_RS06055
uniprot id: A0A7T4EZW6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS05935
gene id: 33037:I6H45_RS05935
uniprot id: A0A6N2QZY9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of the 50S ribosomal subunit.

33037:I6H45 RS08125
gene id: 33037:I6H45_RS08125
uniprot id: A0A6N2TFX8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02710
gene id: 33037:I6H45_RS02710
uniprot id: A0A7T4F1T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

33037:I6H45 RS04100
gene id: 33037:I6H45_RS04100
uniprot id: A0A7T4F2C2
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07945
gene id: 33037:I6H45_RS07945
uniprot id: A0A7T4F0Q6
names: Similarity
messages: Belongs to the EamA transporter family.

33037:I6H45 RS04385
gene id: 33037:I6H45_RS04385
uniprot id: A0A7T4F2E3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

33037:I6H45 RS00315
gene id: 33037:I6H45_RS00315
uniprot id: A0A7T4F1A7
names: Subcellular Location Annotation
messages: Cytoplasm

33037:I6H45 RS07440
gene id: 33037:I6H45_RS07440
uniprot id: A0A7T4K4Z7
names: Function
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.

33037:I6H45 RS05620
gene id: 33037:I6H45_RS05620
uniprot id: A0A7T4EZZ7
names: Similarity
messages: Belongs to the asp23 family.

33037:I6H45 RS01035
gene id: 33037:I6H45_RS01035
uniprot id: A0A7T4K5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

33037:I6H45 RS01825
gene id: 33037:I6H45_RS01825
uniprot id: A0A7T4F1G7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

33037:I6H45 RS06500
gene id: 33037:I6H45_RS06500
uniprot id: A0A7T4F0A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

33037:I6H45 RS07250
gene id: 33037:I6H45_RS07250
uniprot id: A0A7T4F093
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

33037:I6H45 RS08785
gene id: 33037:I6H45_RS08785
uniprot id: A0A7T4K5F5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

33037:I6H45 RS08775
gene id: 33037:I6H45_RS08775
uniprot id: A0A7T4K559
names: Similarity
messages: Belongs to the CinA family.

33037:I6H45 RS02680
gene id: 33037:I6H45_RS02680
uniprot id: A0A7T4F286
names: Similarity
messages: Belongs to the ribF family.

33037:I6H45 RS04720
gene id: 33037:I6H45_RS04720
uniprot id: A0A7T4EZK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

33037:I6H45 RS01880
gene id: 33037:I6H45_RS01880
uniprot id: A0A7T4F2F8
names: Similarity
messages: Belongs to the FBPase class 3 family.

33037:I6H45 RS00270
gene id: 33037:I6H45_RS00270
uniprot id: A0A7T4F140
names: Function
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).

33037:I6H45 RS03625
gene id: 33037:I6H45_RS03625
uniprot id: A0A7T4F2F9
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04365
gene id: 33037:I6H45_RS04365
uniprot id: A0A6N2U491
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

33037:I6H45 RS04390
gene id: 33037:I6H45_RS04390
uniprot id: A0A7T4F2R9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

33037:I6H45 RS08605
gene id: 33037:I6H45_RS08605
uniprot id: A0A7T4F0S0
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

33037:I6H45 RS08615
gene id: 33037:I6H45_RS08615
uniprot id: A0A6N2TI36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

33037:I6H45 RS05720
gene id: 33037:I6H45_RS05720
uniprot id: A0A7T4EZP9
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05595
gene id: 33037:I6H45_RS05595
uniprot id: A0A7T4K4T1
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

33037:I6H45 RS04345
gene id: 33037:I6H45_RS04345
uniprot id: A0A7T4F2Q2
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

33037:I6H45 RS04265
gene id: 33037:I6H45_RS04265
uniprot id: A0A6N2U6U7
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

33037:I6H45 RS02020
gene id: 33037:I6H45_RS02020
uniprot id: A0A7T4K5L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell membrane
messages: Probably functions as a manganese efflux pump.

33037:I6H45 RS05540
gene id: 33037:I6H45_RS05540
uniprot id: A0A7T4EZX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

33037:I6H45 RS08250
gene id: 33037:I6H45_RS08250
uniprot id: A0A7T4K515
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
messages: Cell membrane
messages: Membrane
messages: Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.

33037:I6H45 RS07400
gene id: 33037:I6H45_RS07400
uniprot id: A0A7T4F0A7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

33037:I6H45 RS08700
gene id: 33037:I6H45_RS08700
uniprot id: A0A7T4K540
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05230
gene id: 33037:I6H45_RS05230
uniprot id: A0A7T4EZN7
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

33037:I6H45 RS01675
gene id: 33037:I6H45_RS01675
uniprot id: A0A7T4F1E7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

33037:I6H45 RS03575
gene id: 33037:I6H45_RS03575
uniprot id: A0A7T4F2C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

33037:I6H45 RS06465
gene id: 33037:I6H45_RS06465
uniprot id: A0A7T4F0E3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

33037:I6H45 RS05810
gene id: 33037:I6H45_RS05810
uniprot id: A0A7T4EZZ4
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04710
gene id: 33037:I6H45_RS04710
uniprot id: A0A7T4EZD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

33037:I6H45 RS01400
gene id: 33037:I6H45_RS01400
uniprot id: A0A7T4K5Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

33037:I6H45 RS07905
gene id: 33037:I6H45_RS07905
uniprot id: A0A7T4F0N3
names: Function
names: PTM
names: Similarity
messages: Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily.
messages: Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde.
messages: Requires the activating protein CutD to generate the key active site glycyl radical on Gly-824 that is involved in catalysis.

33037:I6H45 RS04645
gene id: 33037:I6H45_RS04645
uniprot id: A0A7T4EZI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

33037:I6H45 RS02705
gene id: 33037:I6H45_RS02705
uniprot id: A0A7T4F217
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: This protein catalyzes the committed step to the synthesis of the acidic phospholipids.

33037:I6H45 RS01900
gene id: 33037:I6H45_RS01900
uniprot id: A0A7T4F1Y5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

33037:I6H45 RS01275
gene id: 33037:I6H45_RS01275
uniprot id: A0A7T4F197
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02340
gene id: 33037:I6H45_RS02340
uniprot id: A0A7T4K5J4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

33037:I6H45 RS08835
gene id: 33037:I6H45_RS08835
uniprot id: A0A7T4F127
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

33037:I6H45 RS03560
gene id: 33037:I6H45_RS03560
uniprot id: A0A7T4F241
names: Similarity
messages: Belongs to the UPF0758 family.

33037:I6H45 RS00580
gene id: 33037:I6H45_RS00580
uniprot id: A0A7T4F135
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

33037:I6H45 RS02660
gene id: 33037:I6H45_RS02660
uniprot id: A0A7T4K5Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

33037:I6H45 RS00335
gene id: 33037:I6H45_RS00335
uniprot id: A0A7T4F102
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

33037:I6H45 RS06885
gene id: 33037:I6H45_RS06885
uniprot id: A0A7T4K511
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

33037:I6H45 RS08370
gene id: 33037:I6H45_RS08370
uniprot id: A0A7T4F0U2
names: Similarity
messages: Belongs to the UPF0237 family.

33037:I6H45 RS08380
gene id: 33037:I6H45_RS08380
uniprot id: A0A7T4F0N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS01575
gene id: 33037:I6H45_RS01575
uniprot id: A0A7T4F1U8
names: Similarity
messages: Belongs to the peptidase M18 family.

33037:I6H45 RS08800
gene id: 33037:I6H45_RS08800
uniprot id: A0A6N2S298
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

33037:I6H45 RS02490
gene id: 33037:I6H45_RS02490
uniprot id: A0A7T4F234
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

33037:I6H45 RS01015
gene id: 33037:I6H45_RS01015
uniprot id: A0A7T4F1G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

33037:I6H45 RS07425
gene id: 33037:I6H45_RS07425
uniprot id: A0A7T4F0C0
names: Caution
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS01075
gene id: 33037:I6H45_RS01075
uniprot id: A0A7T4F179
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

33037:I6H45 RS07340
gene id: 33037:I6H45_RS07340
uniprot id: A0A7T4F0F7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

33037:I6H45 RS03080
gene id: 33037:I6H45_RS03080
uniprot id: A0A7T4F1X7
names: Similarity
messages: Belongs to the peptidase C40 family.

33037:I6H45 RS05945
gene id: 33037:I6H45_RS05945
uniprot id: A0A6N2R1P1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS01985
gene id: 33037:I6H45_RS01985
uniprot id: A0A6N2R4Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

33037:I6H45 RS00810
gene id: 33037:I6H45_RS00810
uniprot id: A0A6N2T7N5
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03470
gene id: 33037:I6H45_RS03470
uniprot id: A0A7T4F2I6
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

33037:I6H45 RS05020
gene id: 33037:I6H45_RS05020
uniprot id: A0A7T4EZG2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

33037:I6H45 RS04735
gene id: 33037:I6H45_RS04735
uniprot id: A0A7T4EZT4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

33037:I6H45 RS03510
gene id: 33037:I6H45_RS03510
uniprot id: A0A7T4F2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

33037:I6H45 RS07320
gene id: 33037:I6H45_RS07320
uniprot id: A0A6N2SZE9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

33037:I6H45 RS02565
gene id: 33037:I6H45_RS02565
uniprot id: A0A7T4F249
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

33037:I6H45 RS02390
gene id: 33037:I6H45_RS02390
uniprot id: A0A7T4F1T6
names: Similarity
messages: In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.

33037:I6H45 RS00350
gene id: 33037:I6H45_RS00350
uniprot id: A0A7T4F149
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

33037:I6H45 RS04725
gene id: 33037:I6H45_RS04725
uniprot id: A0A7T4EZJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

33037:I6H45 RS08580
gene id: 33037:I6H45_RS08580
uniprot id: A0A7T4F0S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

33037:I6H45 RS03720
gene id: 33037:I6H45_RS03720
uniprot id: A0A7T4F284
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

33037:I6H45 RS00020
gene id: 33037:I6H45_RS00020
uniprot id: A0A7T4F0X6
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05045
gene id: 33037:I6H45_RS05045
uniprot id: A0A6N2RP55
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

33037:I6H45 RS05865
gene id: 33037:I6H45_RS05865
uniprot id: A0A7T4EZW0
names: Similarity
messages: Belongs to the LytR/CpsA/Psr (LCP) family.

33037:I6H45 RS04770
gene id: 33037:I6H45_RS04770
uniprot id: A0A7T4EZH8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

33037:I6H45 RS05005
gene id: 33037:I6H45_RS05005
uniprot id: A0A7T4EZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

33037:I6H45 RS00780
gene id: 33037:I6H45_RS00780
uniprot id: A0A7T4K5M0
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

33037:I6H45 RS02300
gene id: 33037:I6H45_RS02300
uniprot id: A0A7T4F1N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.
messages: Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
messages: Cell membrane
messages: Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).
messages: Membrane

33037:I6H45 RS02460
gene id: 33037:I6H45_RS02460
uniprot id: A0A7T4F1Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

33037:I6H45 RS05055
gene id: 33037:I6H45_RS05055
uniprot id: A0A7T4K4K0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

33037:I6H45 RS06775
gene id: 33037:I6H45_RS06775
uniprot id: A0A6N2UKM7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

33037:I6H45 RS04450
gene id: 33037:I6H45_RS04450
uniprot id: A0A7T4F2F3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

33037:I6H45 RS06325
gene id: 33037:I6H45_RS06325
uniprot id: A0A6N2QWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

33037:I6H45 RS06555
gene id: 33037:I6H45_RS06555
uniprot id: A0A7T4K4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

33037:I6H45 RS02675
gene id: 33037:I6H45_RS02675
uniprot id: A0A7T4F1V0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

33037:I6H45 RS03975
gene id: 33037:I6H45_RS03975
uniprot id: A0A7T4F2H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

33037:I6H45 RS01525
gene id: 33037:I6H45_RS01525
uniprot id: A0A7T4F1M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family.
messages: Membrane

33037:I6H45 RS03900
gene id: 33037:I6H45_RS03900
uniprot id: A0A7T4F2G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS04995
gene id: 33037:I6H45_RS04995
uniprot id: A0A7T4K4I8
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

33037:I6H45 RS07730
gene id: 33037:I6H45_RS07730
uniprot id: A0A7T4F0E9
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

33037:I6H45 RS05335
gene id: 33037:I6H45_RS05335
uniprot id: A0A6N2U0P9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

33037:I6H45 RS06605
gene id: 33037:I6H45_RS06605
uniprot id: A0A6N2SUS0
names: Similarity
messages: Belongs to the carbamate kinase family.

33037:I6H45 RS01325
gene id: 33037:I6H45_RS01325
uniprot id: A0A7T4K5P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease N1/T1 family.
messages: Secreted

33037:I6H45 RS05605
gene id: 33037:I6H45_RS05605
uniprot id: A0A7T4K4L1
names: Similarity
messages: Belongs to the acylphosphatase family.

33037:I6H45 RS04320
gene id: 33037:I6H45_RS04320
uniprot id: A0A7T4K633
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05960
gene id: 33037:I6H45_RS05960
uniprot id: A0A7T4EZU3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS05190
gene id: 33037:I6H45_RS05190
uniprot id: A0A7T4EZK9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Homodimer.

33037:I6H45 RS04695
gene id: 33037:I6H45_RS04695
uniprot id: A0A7T4EZF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

33037:I6H45 RS08565
gene id: 33037:I6H45_RS08565
uniprot id: A0A6N2TJ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

33037:I6H45 RS03565
gene id: 33037:I6H45_RS03565
uniprot id: A0A7T4F229
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS07675
gene id: 33037:I6H45_RS07675
uniprot id: A0A7T4F0S1
names: Subcellular Location Annotation
messages: Cell membrane

33037:I6H45 RS01150
gene id: 33037:I6H45_RS01150
uniprot id: A0A7T4K5D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS00165
gene id: 33037:I6H45_RS00165
uniprot id: A0A7T4F185
names: Similarity
messages: Belongs to the LOR family.

33037:I6H45 RS01775
gene id: 33037:I6H45_RS01775
uniprot id: A0A6N2R982
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

33037:I6H45 RS05925
gene id: 33037:I6H45_RS05925
uniprot id: A0A6N2R0Q5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

33037:I6H45 RS02045
gene id: 33037:I6H45_RS02045
uniprot id: A0A7T4F1L9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

33037:I6H45 RS06080
gene id: 33037:I6H45_RS06080
uniprot id: A0A7T4K4Y5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS00195
gene id: 33037:I6H45_RS00195
uniprot id: A0A7T4F130
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS05065
gene id: 33037:I6H45_RS05065
uniprot id: A0A7T4K4S2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

33037:I6H45 RS05705
gene id: 33037:I6H45_RS05705
uniprot id: A0A6N2R471
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

33037:I6H45 RS04400
gene id: 33037:I6H45_RS04400
uniprot id: A0A7T4K637
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

33037:I6H45 RS08080
gene id: 33037:I6H45_RS08080
uniprot id: A0A7T4K522
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

33037:I6H45 RS06065
gene id: 33037:I6H45_RS06065
uniprot id: A0A7T4K4W8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

33037:I6H45 RS08495
gene id: 33037:I6H45_RS08495
uniprot id: A0A7T4F0R6
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

33037:I6H45 RS01510
gene id: 33037:I6H45_RS01510
uniprot id: A0A7T4F1D1
names: Similarity
messages: Belongs to the peptidase M18 family.

33037:I6H45 RS07210
gene id: 33037:I6H45_RS07210
uniprot id: A0A7T4K4Y0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

33037:I6H45 RS05755
gene id: 33037:I6H45_RS05755
uniprot id: A0A7T4K4P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

33037:I6H45 RS05930
gene id: 33037:I6H45_RS05930
uniprot id: A0A7T4K4Q0
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

33037:I6H45 RS02820
gene id: 33037:I6H45_RS02820
uniprot id: A0A7T4F257
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS01950
gene id: 33037:I6H45_RS01950
uniprot id: A0A7T4K5H1
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

33037:I6H45 RS01800
gene id: 33037:I6H45_RS01800
uniprot id: A0A6N2R8C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

33037:I6H45 RS00985
gene id: 33037:I6H45_RS00985
uniprot id: A0A7T4F188
names: Similarity
messages: Belongs to the ThiD family.

33037:I6H45 RS02180
gene id: 33037:I6H45_RS02180
uniprot id: A0A7T4K5V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

33037:I6H45 RS05360
gene id: 33037:I6H45_RS05360
uniprot id: A0A7T4K4J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

33037:I6H45 RS03580
gene id: 33037:I6H45_RS03580
uniprot id: A0A7T4F236
names: Similarity
messages: Belongs to the class-D beta-lactamase family.
messages: Belongs to the transpeptidase family.

33037:I6H45 RS04295
gene id: 33037:I6H45_RS04295
uniprot id: A0A7T4F2G0
names: Function
messages: Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.

33037:I6H45 RS04810
gene id: 33037:I6H45_RS04810
uniprot id: A0A7T4EZU1
names: Similarity
messages: Belongs to the UPF0473 family.

33037:I6H45 RS02620
gene id: 33037:I6H45_RS02620
uniprot id: A0A7T4F1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

33037:I6H45 RS04300
gene id: 33037:I6H45_RS04300
uniprot id: A0A7T4F2L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

33037:I6H45 RS04670
gene id: 33037:I6H45_RS04670
uniprot id: A0A7T4K4H2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS02145
gene id: 33037:I6H45_RS02145
uniprot id: A0A6N2RI18
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02175
gene id: 33037:I6H45_RS02175
uniprot id: A0A7T4K5I4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS07325
gene id: 33037:I6H45_RS07325
uniprot id: A0A7T4F097
names: Similarity
messages: Belongs to the peptidase S41A family.

33037:I6H45 RS06205
gene id: 33037:I6H45_RS06205
uniprot id: A0A6N2QXS1
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS00225
gene id: 33037:I6H45_RS00225
uniprot id: A0A6N2RXF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS06525
gene id: 33037:I6H45_RS06525
uniprot id: A0A7T4F009
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

33037:I6H45 RS06985
gene id: 33037:I6H45_RS06985
uniprot id: A0A7T4F0F4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HCP family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 hybrid [4Fe-2O-2S] cluster.
messages: Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
messages: Cytoplasm

33037:I6H45 RS05670
gene id: 33037:I6H45_RS05670
uniprot id: A0A7T4F029
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

33037:I6H45 RS00765
gene id: 33037:I6H45_RS00765
uniprot id: A0A7T4K5J2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

33037:I6H45 RS05070
gene id: 33037:I6H45_RS05070
uniprot id: A0A7T4K4J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CobB/CobQ family. GatD subfamily.
messages: Forms a heterodimer with MurT.
messages: The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT.

33037:I6H45 RS02480
gene id: 33037:I6H45_RS02480
uniprot id: A0A7T4F2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS07755
gene id: 33037:I6H45_RS07755
uniprot id: A0A7T4K573
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

33037:I6H45 RS08585
gene id: 33037:I6H45_RS08585
uniprot id: A0A6N2TK03
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

33037:I6H45 RS05820
gene id: 33037:I6H45_RS05820
uniprot id: A0A7T4EZT8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05325
gene id: 33037:I6H45_RS05325
uniprot id: A0A7T4EZK2
names: Similarity
messages: Belongs to the XseB family.

33037:I6H45 RS02440
gene id: 33037:I6H45_RS02440
uniprot id: A0A7T4F203
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

33037:I6H45 RS04605
gene id: 33037:I6H45_RS04605
uniprot id: A0A7T4EZK1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

33037:I6H45 RS07920
gene id: 33037:I6H45_RS07920
uniprot id: A0A6N2SJS6
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

33037:I6H45 RS05695
gene id: 33037:I6H45_RS05695
uniprot id: A0A6N2R4M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

33037:I6H45 RS02445
gene id: 33037:I6H45_RS02445
uniprot id: A0A7T4F1S1
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS02055
gene id: 33037:I6H45_RS02055
uniprot id: A0A7T4F1K7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

33037:I6H45 RS07345
gene id: 33037:I6H45_RS07345
uniprot id: A0A7T4F0B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

33037:I6H45 RS01780
gene id: 33037:I6H45_RS01780
uniprot id: A0A7T4F1U9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

33037:I6H45 RS02615
gene id: 33037:I6H45_RS02615
uniprot id: A0A7T4F1R9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

33037:I6H45 RS05395
gene id: 33037:I6H45_RS05395
uniprot id: A0A7T4EZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

33037:I6H45 RS04625
gene id: 33037:I6H45_RS04625
uniprot id: A0A7T4EZB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

33037:I6H45 RS02825
gene id: 33037:I6H45_RS02825
uniprot id: A0A7T4F1X1
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04950
gene id: 33037:I6H45_RS04950
uniprot id: A0A7T4EZE7
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

33037:I6H45 RS05215
gene id: 33037:I6H45_RS05215
uniprot id: A0A7T4K4T3
names: Similarity
messages: Belongs to the UPF0340 family.

33037:I6H45 RS07845
gene id: 33037:I6H45_RS07845
uniprot id: A0A7T4K4Z2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

33037:I6H45 RS02455
gene id: 33037:I6H45_RS02455
uniprot id: A0A7T4F1Q7
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

33037:I6H45 RS07285
gene id: 33037:I6H45_RS07285
uniprot id: A0A7T4K4Y8
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

33037:I6H45 RS06720
gene id: 33037:I6H45_RS06720
uniprot id: A0A6N2UF10
names: Similarity
messages: Belongs to the RutC family.

33037:I6H45 RS01710
gene id: 33037:I6H45_RS01710
uniprot id: A0A6N2RAS2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

33037:I6H45 RS05905
gene id: 33037:I6H45_RS05905
uniprot id: A0A7T4F066
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS06000
gene id: 33037:I6H45_RS06000
uniprot id: A0A7T4K4N2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

33037:I6H45 RS04705
gene id: 33037:I6H45_RS04705
uniprot id: A0A7T4EZC6
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

33037:I6H45 RS06445
gene id: 33037:I6H45_RS06445
uniprot id: A0A7T4K608
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

33037:I6H45 RS06270
gene id: 33037:I6H45_RS06270
uniprot id: A0A7T4EZX2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

33037:I6H45 RS03695
gene id: 33037:I6H45_RS03695
uniprot id: A0A7T4K5U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

33037:I6H45 RS06405
gene id: 33037:I6H45_RS06405
uniprot id: A0A7T4F094
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

33037:I6H45 RS03545
gene id: 33037:I6H45_RS03545
uniprot id: A0A7T4F252
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

33037:I6H45 RS03650
gene id: 33037:I6H45_RS03650
uniprot id: A0A7T4F238
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

33037:I6H45 RS05265
gene id: 33037:I6H45_RS05265
uniprot id: A0A7T4EZL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

33037:I6H45 RS01930
gene id: 33037:I6H45_RS01930
uniprot id: A0A7T4F1I2
names: Similarity
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

33037:I6H45 RS06070
gene id: 33037:I6H45_RS06070
uniprot id: A0A7T4K4R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

33037:I6H45 RS03135
gene id: 33037:I6H45_RS03135
uniprot id: A0A7T4K5R0
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

33037:I6H45 RS03265
gene id: 33037:I6H45_RS03265
uniprot id: A0A7T4F2E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

33037:I6H45 RS02745
gene id: 33037:I6H45_RS02745
uniprot id: A0A6N2TML5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS08750
gene id: 33037:I6H45_RS08750
uniprot id: A0A7T4F0X9
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

33037:I6H45 RS03790
gene id: 33037:I6H45_RS03790
uniprot id: A0A7T4F2N5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

33037:I6H45 RS01160
gene id: 33037:I6H45_RS01160
uniprot id: A0A7T4K5N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

33037:I6H45 RS08520
gene id: 33037:I6H45_RS08520
uniprot id: A0A7T4F0V8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03755
gene id: 33037:I6H45_RS03755
uniprot id: A0A7T4K611
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

33037:I6H45 RS02520
gene id: 33037:I6H45_RS02520
uniprot id: A0A7T4F213
names: Similarity
messages: Belongs to the PdxS/SNZ family.

33037:I6H45 RS06015
gene id: 33037:I6H45_RS06015
uniprot id: A0A7T4F044
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

33037:I6H45 RS02695
gene id: 33037:I6H45_RS02695
uniprot id: A0A7T4F1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

33037:I6H45 RS03780
gene id: 33037:I6H45_RS03780
uniprot id: A0A7T4F2H7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS02595
gene id: 33037:I6H45_RS02595
uniprot id: A0A7T4F224
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS01705
gene id: 33037:I6H45_RS01705
uniprot id: A0A6N2R977
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

33037:I6H45 RS07055
gene id: 33037:I6H45_RS07055
uniprot id: A0A7T4K4W3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

33037:I6H45 RS06550
gene id: 33037:I6H45_RS06550
uniprot id: A0A7T4K4Z5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

33037:I6H45 RS04040
gene id: 33037:I6H45_RS04040
uniprot id: A0A7T4F293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS06855
gene id: 33037:I6H45_RS06855
uniprot id: A0A7T4F043
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

33037:I6H45 RS05675
gene id: 33037:I6H45_RS05675
uniprot id: A0A6N2R3F0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

33037:I6H45 RS04520
gene id: 33037:I6H45_RS04520
uniprot id: A0A7T4F2H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

33037:I6H45 RS06970
gene id: 33037:I6H45_RS06970
uniprot id: A0A6N2UE50
names: Similarity
messages: Belongs to the FldB/FldC dehydratase alpha/beta subunit family.

33037:I6H45 RS08195
gene id: 33037:I6H45_RS08195
uniprot id: A0A7T4F0K5
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

33037:I6H45 RS01835
gene id: 33037:I6H45_RS01835
uniprot id: A0A7T4F1G9
names: Similarity
messages: Belongs to the RNase H family.

33037:I6H45 RS07625
gene id: 33037:I6H45_RS07625
uniprot id: A0A7T4K4Z6
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

33037:I6H45 RS05765
gene id: 33037:I6H45_RS05765
uniprot id: A0A6N2R3V1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

33037:I6H45 RS01410
gene id: 33037:I6H45_RS01410
uniprot id: A0A7T4F1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

33037:I6H45 RS07300
gene id: 33037:I6H45_RS07300
uniprot id: A0A7T4K4X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

33037:I6H45 RS04690
gene id: 33037:I6H45_RS04690
uniprot id: A0A7T4EZL0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

33037:I6H45 RS05250
gene id: 33037:I6H45_RS05250
uniprot id: A0A7T4EZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

33037:I6H45 RS00325
gene id: 33037:I6H45_RS00325
uniprot id: A0A7T4F1F1
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03480
gene id: 33037:I6H45_RS03480
uniprot id: A0A7T4F228
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS00320
gene id: 33037:I6H45_RS00320
uniprot id: A0A7T4F121
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08595
gene id: 33037:I6H45_RS08595
uniprot id: A0A7T4F0W5
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

33037:I6H45 RS02640
gene id: 33037:I6H45_RS02640
uniprot id: A0A7T4F261
names: Similarity
messages: Belongs to the EamA transporter family.

33037:I6H45 RS01480
gene id: 33037:I6H45_RS01480
uniprot id: A0A7T4K5R1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

33037:I6H45 RS05350
gene id: 33037:I6H45_RS05350
uniprot id: A0A7T4K4R6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcAL family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS08480
gene id: 33037:I6H45_RS08480
uniprot id: A0A6N2TG89
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS01375
gene id: 33037:I6H45_RS01375
uniprot id: A0A7T4F1B0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

33037:I6H45 RS08640
gene id: 33037:I6H45_RS08640
uniprot id: A0A7T4F106
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05480
gene id: 33037:I6H45_RS05480
uniprot id: A0A7T4EZM4
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

33037:I6H45 RS06310
gene id: 33037:I6H45_RS06310
uniprot id: A0A7T4K4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

33037:I6H45 RS04440
gene id: 33037:I6H45_RS04440
uniprot id: A0A7T4F2W5
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

33037:I6H45 RS08875
gene id: 33037:I6H45_RS08875
uniprot id: A0A7T4F138
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05560
gene id: 33037:I6H45_RS05560
uniprot id: A0A7T4EZN2
names: Similarity
messages: Belongs to the peptidase C40 family.

33037:I6H45 RS06115
gene id: 33037:I6H45_RS06115
uniprot id: A0A6N2R002
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

33037:I6H45 RS07305
gene id: 33037:I6H45_RS07305
uniprot id: A0A7T4F0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

33037:I6H45 RS08840
gene id: 33037:I6H45_RS08840
uniprot id: A0A7T4F0U5
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

33037:I6H45 RS03485
gene id: 33037:I6H45_RS03485
uniprot id: A0A7T4F219
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05860
gene id: 33037:I6H45_RS05860
uniprot id: A0A7T4F027
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS04945
gene id: 33037:I6H45_RS04945
uniprot id: A0A6N2RQC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

33037:I6H45 RS06560
gene id: 33037:I6H45_RS06560
uniprot id: A0A7T4K4R8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

33037:I6H45 RS03710
gene id: 33037:I6H45_RS03710
uniprot id: A0A6N2RUV8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

33037:I6H45 RS01720
gene id: 33037:I6H45_RS01720
uniprot id: A0A6N2R9G2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

33037:I6H45 RS08930
gene id: 33037:I6H45_RS08930
uniprot id: A0A7T4K5E4
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04530
gene id: 33037:I6H45_RS04530
uniprot id: A0A7T4F2H8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

33037:I6H45 RS07860
gene id: 33037:I6H45_RS07860
uniprot id: A0A7T4K508
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

33037:I6H45 RS00490
gene id: 33037:I6H45_RS00490
uniprot id: A0A7T4F117
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

33037:I6H45 RS07090
gene id: 33037:I6H45_RS07090
uniprot id: A0A7T4F071
names: Similarity
messages: Belongs to the peptidase S51 family.

33037:I6H45 RS01465
gene id: 33037:I6H45_RS01465
uniprot id: A0A7T4K5I1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

33037:I6H45 RS04635
gene id: 33037:I6H45_RS04635
uniprot id: A0A7T4EZB9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

33037:I6H45 RS04985
gene id: 33037:I6H45_RS04985
uniprot id: A0A7T4K4H3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS05450
gene id: 33037:I6H45_RS05450
uniprot id: A0A6N2U241
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

33037:I6H45 RS00775
gene id: 33037:I6H45_RS00775
uniprot id: A0A7T4K5A7
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

33037:I6H45 RS03620
gene id: 33037:I6H45_RS03620
uniprot id: A0A7T4K5T7
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05510
gene id: 33037:I6H45_RS05510
uniprot id: A0A7T4F015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

33037:I6H45 RS05940
gene id: 33037:I6H45_RS05940
uniprot id: A0A6N2R129
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS06370
gene id: 33037:I6H45_RS06370
uniprot id: A0A7T4F0C6
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

33037:I6H45 RS02575
gene id: 33037:I6H45_RS02575
uniprot id: A0A7T4K5Q0
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

33037:I6H45 RS00520
gene id: 33037:I6H45_RS00520
uniprot id: A0A7T4F1F0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

33037:I6H45 RS04760
gene id: 33037:I6H45_RS04760
uniprot id: A0A7T4K4H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

33037:I6H45 RS02435
gene id: 33037:I6H45_RS02435
uniprot id: A0A7T4K5L8
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

33037:I6H45 RS03075
gene id: 33037:I6H45_RS03075
uniprot id: A0A7T4F1Y3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

33037:I6H45 RS00805
gene id: 33037:I6H45_RS00805
uniprot id: A0A7T4F160
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

33037:I6H45 RS01435
gene id: 33037:I6H45_RS01435
uniprot id: A0A7T4F1C2
names: Similarity
messages: Belongs to the ArsC family.

33037:I6H45 RS00285
gene id: 33037:I6H45_RS00285
uniprot id: A0A7T4F1B7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

33037:I6H45 RS08805
gene id: 33037:I6H45_RS08805
uniprot id: A0A7T4F186
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

33037:I6H45 RS01555
gene id: 33037:I6H45_RS01555
uniprot id: A0A7T4K5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02525
gene id: 33037:I6H45_RS02525
uniprot id: A0A7T4F1S5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

33037:I6H45 RS00840
gene id: 33037:I6H45_RS00840
uniprot id: A0A7T4K5J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

33037:I6H45 RS05390
gene id: 33037:I6H45_RS05390
uniprot id: A0A6N2TYW3
names: Caution
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

33037:I6H45 RS05730
gene id: 33037:I6H45_RS05730
uniprot id: A0A7T4EZX5
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

33037:I6H45 RS07900
gene id: 33037:I6H45_RS07900
uniprot id: A0A7T4F0N8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via an homolytic cleavage of S-adenosyl-L-methionine (SAM).

33037:I6H45 RS03770
gene id: 33037:I6H45_RS03770
uniprot id: A0A7T4K646
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

33037:I6H45 RS00440
gene id: 33037:I6H45_RS00440
uniprot id: A0A6N2SXV4
names: Similarity
messages: Belongs to the ycf81 family.

33037:I6H45 RS04860
gene id: 33037:I6H45_RS04860
uniprot id: A0A7T4EZD5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

33037:I6H45 RS04935
gene id: 33037:I6H45_RS04935
uniprot id: A0A7T4EZW1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04815
gene id: 33037:I6H45_RS04815
uniprot id: A0A6N2U8H7
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

33037:I6H45 RS08145
gene id: 33037:I6H45_RS08145
uniprot id: A0A7T4F0Z0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

33037:I6H45 RS08845
gene id: 33037:I6H45_RS08845
uniprot id: A0A7T4F169
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

33037:I6H45 RS04380
gene id: 33037:I6H45_RS04380
uniprot id: A0A6N2U737
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

33037:I6H45 RS07010
gene id: 33037:I6H45_RS07010
uniprot id: A0A6N2UFT1
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

33037:I6H45 RS07420
gene id: 33037:I6H45_RS07420
uniprot id: A0A7T4F0H1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS02610
gene id: 33037:I6H45_RS02610
uniprot id: A0A7T4F1S3
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

33037:I6H45 RS06355
gene id: 33037:I6H45_RS06355
uniprot id: A0A6N2QWQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

33037:I6H45 RS04940
gene id: 33037:I6H45_RS04940
uniprot id: A0A6N2RRH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

33037:I6H45 RS05830
gene id: 33037:I6H45_RS05830
uniprot id: A0A7T4K4U9
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08720
gene id: 33037:I6H45_RS08720
uniprot id: A0A7T4F116
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

33037:I6H45 RS01025
gene id: 33037:I6H45_RS01025
uniprot id: A0A7T4F1K0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

33037:I6H45 RS07385
gene id: 33037:I6H45_RS07385
uniprot id: A0A7T4F0D1
names: Similarity
messages: Belongs to the peptidase C40 family.

33037:I6H45 RS08795
gene id: 33037:I6H45_RS08795
uniprot id: A0A7T4F128
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).

33037:I6H45 RS04600
gene id: 33037:I6H45_RS04600
uniprot id: A0A7T4K4G3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

33037:I6H45 RS04370
gene id: 33037:I6H45_RS04370
uniprot id: A0A6N2U6E8
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

33037:I6H45 RS05035
gene id: 33037:I6H45_RS05035
uniprot id: A0A7T4EZN6
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

33037:I6H45 RS01455
gene id: 33037:I6H45_RS01455
uniprot id: A0A7T4F1Q6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

33037:I6H45 RS05000
gene id: 33037:I6H45_RS05000
uniprot id: A0A6N2RPV1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

33037:I6H45 RS07405
gene id: 33037:I6H45_RS07405
uniprot id: A0A7T4F0B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02210
gene id: 33037:I6H45_RS02210
uniprot id: A0A7T4F1N7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS08210
gene id: 33037:I6H45_RS08210
uniprot id: A0A7T4K601
names: Similarity
messages: Belongs to the polysaccharide synthase family.

33037:I6H45 RS06180
gene id: 33037:I6H45_RS06180
uniprot id: A0A7T4EZY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

33037:I6H45 RS06410
gene id: 33037:I6H45_RS06410
uniprot id: A0A7T4F019
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GdpP/PdeA phosphodiesterase family.
messages: Cell membrane
messages: For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.
messages: Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

33037:I6H45 RS05410
gene id: 33037:I6H45_RS05410
uniprot id: A0A6N2U1M0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

33037:I6H45 RS03775
gene id: 33037:I6H45_RS03775
uniprot id: A0A7T4K5U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-C family. DnaE subfamily.
messages: Cytoplasm
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.

33037:I6H45 RS06335
gene id: 33037:I6H45_RS06335
uniprot id: A0A7T4F0D7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

33037:I6H45 RS00330
gene id: 33037:I6H45_RS00330
uniprot id: A0A7T4F101
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

33037:I6H45 RS06860
gene id: 33037:I6H45_RS06860
uniprot id: A0A7T4F0A9
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

33037:I6H45 RS03895
gene id: 33037:I6H45_RS03895
uniprot id: A0A7T4F2A8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06315
gene id: 33037:I6H45_RS06315
uniprot id: A0A7T4K4Z8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

33037:I6H45 RS07750
gene id: 33037:I6H45_RS07750
uniprot id: A0A7T4F0S9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

33037:I6H45 RS01490
gene id: 33037:I6H45_RS01490
uniprot id: A0A6N2RER3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

33037:I6H45 RS05405
gene id: 33037:I6H45_RS05405
uniprot id: A0A7T4EZT5
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

33037:I6H45 RS01765
gene id: 33037:I6H45_RS01765
uniprot id: A0A6N2R7T7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

33037:I6H45 RS03635
gene id: 33037:I6H45_RS03635
uniprot id: A0A7T4F2L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

33037:I6H45 RS06900
gene id: 33037:I6H45_RS06900
uniprot id: A0A7T4K542
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

33037:I6H45 RS01620
gene id: 33037:I6H45_RS01620
uniprot id: A0A6N2RA80
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

33037:I6H45 RS04250
gene id: 33037:I6H45_RS04250
uniprot id: A0A7T4K5W4
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

33037:I6H45 RS02295
gene id: 33037:I6H45_RS02295
uniprot id: A0A7T4F1P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02430
gene id: 33037:I6H45_RS02430
uniprot id: A0A6N2TV07
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

33037:I6H45 RS06615
gene id: 33037:I6H45_RS06615
uniprot id: A0A7T4F077
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arginine deiminase family.
messages: Cytoplasm

33037:I6H45 RS07915
gene id: 33037:I6H45_RS07915
uniprot id: A0A6N2SFZ7
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

33037:I6H45 RS03630
gene id: 33037:I6H45_RS03630
uniprot id: A0A7T4F262
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04700
gene id: 33037:I6H45_RS04700
uniprot id: A0A7T4EZS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

33037:I6H45 RS08675
gene id: 33037:I6H45_RS08675
uniprot id: A0A6N2S424
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

33037:I6H45 RS08155
gene id: 33037:I6H45_RS08155
uniprot id: A0A7T4K523
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

33037:I6H45 RS07235
gene id: 33037:I6H45_RS07235
uniprot id: A0A6N2SCY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flotillin-like FloA family.
messages: Cell membrane
messages: Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.
messages: Homooligomerizes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

33037:I6H45 RS05165
gene id: 33037:I6H45_RS05165
uniprot id: A0A6N2U025
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

33037:I6H45 RS01910
gene id: 33037:I6H45_RS01910
uniprot id: A0A7T4F1I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

33037:I6H45 RS00010
gene id: 33037:I6H45_RS00010
uniprot id: A0A7T4K589
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
messages: In the N-terminal section; belongs to the MsrA Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS06595
gene id: 33037:I6H45_RS06595
uniprot id: A0A7T4F026
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05920
gene id: 33037:I6H45_RS05920
uniprot id: A0A7T4K4M7
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05340
gene id: 33037:I6H45_RS05340
uniprot id: A0A7T4EZN0
names: Similarity
messages: Belongs to the asp23 family.

33037:I6H45 RS02000
gene id: 33037:I6H45_RS02000
uniprot id: A0A7T4F1S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05590
gene id: 33037:I6H45_RS05590
uniprot id: A0A7T4F024
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

33037:I6H45 RS04965
gene id: 33037:I6H45_RS04965
uniprot id: A0A7T4EZH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PrsA family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.

33037:I6H45 RS01685
gene id: 33037:I6H45_RS01685
uniprot id: A0A6N2RAE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

33037:I6H45 RS05245
gene id: 33037:I6H45_RS05245
uniprot id: A0A6N2U0X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane

33037:I6H45 RS08600
gene id: 33037:I6H45_RS08600
uniprot id: A0A6N2TNS9
names: Function
names: Similarity
messages: Belongs to the V-ATPase F subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

33037:I6H45 RS04485
gene id: 33037:I6H45_RS04485
uniprot id: A0A7T4K653
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS08035
gene id: 33037:I6H45_RS08035
uniprot id: A0A7T4F0K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease M5 family.
messages: Cytoplasm
messages: Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.

33037:I6H45 RS07685
gene id: 33037:I6H45_RS07685
uniprot id: A0A7T4K510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

33037:I6H45 RS05210
gene id: 33037:I6H45_RS05210
uniprot id: A0A7T4K4I7
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06865
gene id: 33037:I6H45_RS06865
uniprot id: A0A7T4F096
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

33037:I6H45 RS02320
gene id: 33037:I6H45_RS02320
uniprot id: A0A7T4F1N2
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

33037:I6H45 RS01745
gene id: 33037:I6H45_RS01745
uniprot id: A0A7T4F1W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

33037:I6H45 RS05435
gene id: 33037:I6H45_RS05435
uniprot id: A0A7T4K4K4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

33037:I6H45 RS01755
gene id: 33037:I6H45_RS01755
uniprot id: A0A6N2R7X4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

33037:I6H45 RS00055
gene id: 33037:I6H45_RS00055
uniprot id: A0A7T4F0W0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03745
gene id: 33037:I6H45_RS03745
uniprot id: A0A6N2RU18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

33037:I6H45 RS08500
gene id: 33037:I6H45_RS08500
uniprot id: A0A7T4F153
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

33037:I6H45 RS07940
gene id: 33037:I6H45_RS07940
uniprot id: A0A7T4K528
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

33037:I6H45 RS01285
gene id: 33037:I6H45_RS01285
uniprot id: A0A6N2RBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

33037:I6H45 RS05270
gene id: 33037:I6H45_RS05270
uniprot id: A0A7T4EZZ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

33037:I6H45 RS06125
gene id: 33037:I6H45_RS06125
uniprot id: A0A7T4F022
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

33037:I6H45 RS00565
gene id: 33037:I6H45_RS00565
uniprot id: A0A7T4F1H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

33037:I6H45 RS08735
gene id: 33037:I6H45_RS08735
uniprot id: A0A6N2S1R9
names: Similarity
messages: Belongs to the thioredoxin family.

33037:I6H45 RS01505
gene id: 33037:I6H45_RS01505
uniprot id: A0A7T4F1D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
messages: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
messages: Cytoplasm
messages: Homodimer.

33037:I6H45 RS04640
gene id: 33037:I6H45_RS04640
uniprot id: A0A7T4EZJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

33037:I6H45 RS07365
gene id: 33037:I6H45_RS07365
uniprot id: A0A7T4K4W4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

33037:I6H45 RS08470
gene id: 33037:I6H45_RS08470
uniprot id: A0A6N2TFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

33037:I6H45 RS07715
gene id: 33037:I6H45_RS07715
uniprot id: A0A6N2SNU6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

33037:I6H45 RS02645
gene id: 33037:I6H45_RS02645
uniprot id: A0A7T4K5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

33037:I6H45 RS03245
gene id: 33037:I6H45_RS03245
uniprot id: A0A7T4F1Z2
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03785
gene id: 33037:I6H45_RS03785
uniprot id: A0A7T4F282
names: Similarity
messages: Belongs to the pyruvate kinase family.
messages: In the C-terminal section; belongs to the PEP-utilizing enzyme family.

33037:I6H45 RS08915
gene id: 33037:I6H45_RS08915
uniprot id: A0A7T4F136
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

33037:I6H45 RS05170
gene id: 33037:I6H45_RS05170
uniprot id: A0A6N2U106
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

33037:I6H45 RS08475
gene id: 33037:I6H45_RS08475
uniprot id: A0A6N2TG57
names: Subcellular Location Annotation
messages: Cytoplasm

33037:I6H45 RS07310
gene id: 33037:I6H45_RS07310
uniprot id: A0A7T4F0B6
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

33037:I6H45 RS06230
gene id: 33037:I6H45_RS06230
uniprot id: A0A7T4K4S4
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02845
gene id: 33037:I6H45_RS02845
uniprot id: A0A7T4F1U3
names: Similarity
messages: Belongs to the MobA/MobL family.

33037:I6H45 RS07290
gene id: 33037:I6H45_RS07290
uniprot id: A0A7T4K4V9
names: Function
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.

33037:I6H45 RS08920
gene id: 33037:I6H45_RS08920
uniprot id: A0A7T4F0V5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

33037:I6H45 RS02395
gene id: 33037:I6H45_RS02395
uniprot id: A0A7T4F1X5
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: In the C-terminal section; belongs to the NAD synthetase family.

33037:I6H45 RS01155
gene id: 33037:I6H45_RS01155
uniprot id: A0A7T4K5C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

33037:I6H45 RS08300
gene id: 33037:I6H45_RS08300
uniprot id: A0A7T4F0W3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

33037:I6H45 RS07600
gene id: 33037:I6H45_RS07600
uniprot id: A0A7T4F0R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.
messages: Homodimer.

33037:I6H45 RS07220
gene id: 33037:I6H45_RS07220
uniprot id: A0A7T4K561
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

33037:I6H45 RS05535
gene id: 33037:I6H45_RS05535
uniprot id: A0A7T4K4M6
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

33037:I6H45 RS04325
gene id: 33037:I6H45_RS04325
uniprot id: A0A7T4K5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS05345
gene id: 33037:I6H45_RS05345
uniprot id: A0A6N2TYI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

33037:I6H45 RS08680
gene id: 33037:I6H45_RS08680
uniprot id: A0A7T4F0S3
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

33037:I6H45 RS08290
gene id: 33037:I6H45_RS08290
uniprot id: A0A6N2TDA4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

33037:I6H45 RS05115
gene id: 33037:I6H45_RS05115
uniprot id: A0A6N2RLG9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

33037:I6H45 RS05715
gene id: 33037:I6H45_RS05715
uniprot id: A0A7T4EZP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

33037:I6H45 RS06435
gene id: 33037:I6H45_RS06435
uniprot id: A0A7T4F000
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

33037:I6H45 RS05790
gene id: 33037:I6H45_RS05790
uniprot id: A0A7T4EZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS08825
gene id: 33037:I6H45_RS08825
uniprot id: A0A7T4F0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

33037:I6H45 RS03880
gene id: 33037:I6H45_RS03880
uniprot id: A0A7T4F2A4
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06755
gene id: 33037:I6H45_RS06755
uniprot id: A0A7T4F053
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

33037:I6H45 RS03540
gene id: 33037:I6H45_RS03540
uniprot id: A0A6N2TKN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

33037:I6H45 RS02685
gene id: 33037:I6H45_RS02685
uniprot id: A0A7T4F1T3
names: Similarity
messages: Belongs to the PRORSD1 family.

33037:I6H45 RS01515
gene id: 33037:I6H45_RS01515
uniprot id: A0A7T4F1D2
names: Similarity
messages: Belongs to the UPF0045 family.

33037:I6H45 RS07990
gene id: 33037:I6H45_RS07990
uniprot id: A0A7T4F0W9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

33037:I6H45 RS06105
gene id: 33037:I6H45_RS06105
uniprot id: A0A6N2QXP7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

33037:I6H45 RS02510
gene id: 33037:I6H45_RS02510
uniprot id: A0A7T4K5X4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

33037:I6H45 RS07205
gene id: 33037:I6H45_RS07205
uniprot id: A0A7T4K538
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

33037:I6H45 RS01290
gene id: 33037:I6H45_RS01290
uniprot id: A0A7T4F1J1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

33037:I6H45 RS08455
gene id: 33037:I6H45_RS08455
uniprot id: A0A7T4F0P8
names: Similarity
messages: Belongs to the aldolase LacD family.

33037:I6H45 RS05950
gene id: 33037:I6H45_RS05950
uniprot id: A0A6N2QZF5
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

33037:I6H45 RS00045
gene id: 33037:I6H45_RS00045
uniprot id: A0A7T4F111
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05455
gene id: 33037:I6H45_RS05455
uniprot id: A0A7T4EZR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

33037:I6H45 RS06020
gene id: 33037:I6H45_RS06020
uniprot id: A0A7T4EZX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

33037:I6H45 RS00975
gene id: 33037:I6H45_RS00975
uniprot id: A0A7T4K5E3
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05515
gene id: 33037:I6H45_RS05515
uniprot id: A0A6N2R692
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

33037:I6H45 RS01170
gene id: 33037:I6H45_RS01170
uniprot id: A0A7T4F1J4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

33037:I6H45 RS01855
gene id: 33037:I6H45_RS01855
uniprot id: A0A7T4F1V9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

33037:I6H45 RS01990
gene id: 33037:I6H45_RS01990
uniprot id: A0A6N2R617
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

33037:I6H45 RS00605
gene id: 33037:I6H45_RS00605
uniprot id: A0A7T4F1G0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

33037:I6H45 RS00065
gene id: 33037:I6H45_RS00065
uniprot id: A0A7T4K5E8
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily.

33037:I6H45 RS06515
gene id: 33037:I6H45_RS06515
uniprot id: A0A7T4F012
names: Similarity
messages: Belongs to the UPF0102 family.

33037:I6H45 RS01840
gene id: 33037:I6H45_RS01840
uniprot id: A0A7T4F1L6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

33037:I6H45 RS08765
gene id: 33037:I6H45_RS08765
uniprot id: A0A7T4F165
names: Similarity
messages: Belongs to the ParB family.

33037:I6H45 RS02735
gene id: 33037:I6H45_RS02735
uniprot id: A0A7T4K5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

33037:I6H45 RS08095
gene id: 33037:I6H45_RS08095
uniprot id: A0A7T4K536
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

33037:I6H45 RS05910
gene id: 33037:I6H45_RS05910
uniprot id: A0A7T4K4V4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

33037:I6H45 RS06610
gene id: 33037:I6H45_RS06610
uniprot id: A0A6N2SUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

33037:I6H45 RS03675
gene id: 33037:I6H45_RS03675
uniprot id: A0A7T4K606
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

33037:I6H45 RS08010
gene id: 33037:I6H45_RS08010
uniprot id: A0A7T4K5A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).

33037:I6H45 RS04895
gene id: 33037:I6H45_RS04895
uniprot id: A0A7T4K4N5
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08425
gene id: 33037:I6H45_RS08425
uniprot id: A0A7T4F144
names: Similarity
messages: Belongs to the KdgT transporter family.

33037:I6H45 RS06085
gene id: 33037:I6H45_RS06085
uniprot id: A0A7T4K4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

33037:I6H45 RS05180
gene id: 33037:I6H45_RS05180
uniprot id: A0A7T4EZQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

33037:I6H45 RS06090
gene id: 33037:I6H45_RS06090
uniprot id: A0A7T4F051
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS04870
gene id: 33037:I6H45_RS04870
uniprot id: A0A7T4EZE1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

33037:I6H45 RS07480
gene id: 33037:I6H45_RS07480
uniprot id: A0A7T4F0B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

33037:I6H45 RS07270
gene id: 33037:I6H45_RS07270
uniprot id: A0A7T4F0A3
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

33037:I6H45 RS05185
gene id: 33037:I6H45_RS05185
uniprot id: A0A7T4EZQ7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

33037:I6H45 RS03995
gene id: 33037:I6H45_RS03995
uniprot id: A0A7T4K607
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

33037:I6H45 RS06455
gene id: 33037:I6H45_RS06455
uniprot id: A0A7T4F058
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.

33037:I6H45 RS05645
gene id: 33037:I6H45_RS05645
uniprot id: A0A7T4EZN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDH/MDH superfamily. LDH family.
messages: Catalyzes the conversion of lactate to pyruvate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04930
gene id: 33037:I6H45_RS04930
uniprot id: A0A7T4EZJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

33037:I6H45 RS03970
gene id: 33037:I6H45_RS03970
uniprot id: A0A7T4F2C1
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

33037:I6H45 RS05420
gene id: 33037:I6H45_RS05420
uniprot id: A0A7T4F004
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

33037:I6H45 RS04435
gene id: 33037:I6H45_RS04435
uniprot id: A0A7T4F2G1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS02110
gene id: 33037:I6H45_RS02110
uniprot id: A0A7T4K5K2
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

33037:I6H45 RS08540
gene id: 33037:I6H45_RS08540
uniprot id: A0A7T4K5B7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

33037:I6H45 RS06365
gene id: 33037:I6H45_RS06365
uniprot id: A0A7T4EZZ2
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02065
gene id: 33037:I6H45_RS02065
uniprot id: A0A6N2RKE8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08285
gene id: 33037:I6H45_RS08285
uniprot id: A0A7T4F0L6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

33037:I6H45 RS02935
gene id: 33037:I6H45_RS02935
uniprot id: A0A7T4F250
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

33037:I6H45 RS05240
gene id: 33037:I6H45_RS05240
uniprot id: A0A7T4EZH6
names: Similarity
messages: Belongs to the V-ATPase F subunit family.

33037:I6H45 RS06915
gene id: 33037:I6H45_RS06915
uniprot id: A0A7T4F074
names: Similarity
messages: Belongs to the peptidase S58 family.

33037:I6H45 RS03750
gene id: 33037:I6H45_RS03750
uniprot id: A0A6N2RTN5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

33037:I6H45 RS05785
gene id: 33037:I6H45_RS05785
uniprot id: A0A7T4F073
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07195
gene id: 33037:I6H45_RS07195
uniprot id: A0A6N2SC52
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

33037:I6H45 RS00610
gene id: 33037:I6H45_RS00610
uniprot id: A0A7T4K5I2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

33037:I6H45 RS01980
gene id: 33037:I6H45_RS01980
uniprot id: A0A6N2R517
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

33037:I6H45 RS06245
gene id: 33037:I6H45_RS06245
uniprot id: A0A7T4K4S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Homotetramer.
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

33037:I6H45 RS00450
gene id: 33037:I6H45_RS00450
uniprot id: A0A7T4K5A4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS04900
gene id: 33037:I6H45_RS04900
uniprot id: A0A7T4K4J0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS00145
gene id: 33037:I6H45_RS00145
uniprot id: A0A7T4K583
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

33037:I6H45 RS08450
gene id: 33037:I6H45_RS08450
uniprot id: A0A7T4F0Y5
names: Similarity
messages: Belongs to the SIS family. AgaS subfamily.

33037:I6H45 RS05735
gene id: 33037:I6H45_RS05735
uniprot id: A0A7T4EZX8
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

33037:I6H45 RS05915
gene id: 33037:I6H45_RS05915
uniprot id: A0A7T4K4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

33037:I6H45 RS01965
gene id: 33037:I6H45_RS01965
uniprot id: A0A7T4F1U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS06050
gene id: 33037:I6H45_RS06050
uniprot id: A0A7T4F014
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS06330
gene id: 33037:I6H45_RS06330
uniprot id: A0A7T4F008
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

33037:I6H45 RS05290
gene id: 33037:I6H45_RS05290
uniprot id: A0A7T4K4T9
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

33037:I6H45 RS01795
gene id: 33037:I6H45_RS01795
uniprot id: A0A6N2RB34
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

33037:I6H45 RS01760
gene id: 33037:I6H45_RS01760
uniprot id: A0A6N2RBH3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

33037:I6H45 RS00655
gene id: 33037:I6H45_RS00655
uniprot id: A0A7T4F143
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02910
gene id: 33037:I6H45_RS02910
uniprot id: A0A7T4F2B9
names: Similarity
messages: Belongs to the peptidase C40 family.

33037:I6H45 RS03740
gene id: 33037:I6H45_RS03740
uniprot id: A0A7T4F2D8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

33037:I6H45 RS07185
gene id: 33037:I6H45_RS07185
uniprot id: A0A7T4F0E8
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

33037:I6H45 RS07490
gene id: 33037:I6H45_RS07490
uniprot id: A0A7T4F0I6
names: Subcellular Location Annotation
messages: cell wall

33037:I6H45 RS08590
gene id: 33037:I6H45_RS08590
uniprot id: A0A7T4F0R1
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

33037:I6H45 RS01180
gene id: 33037:I6H45_RS01180
uniprot id: A0A6N2S643
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

33037:I6H45 RS06580
gene id: 33037:I6H45_RS06580
uniprot id: A0A7T4F042
names: Function
names: Similarity
messages: Belongs to the UPF0122 family.
messages: Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.

33037:I6H45 RS02650
gene id: 33037:I6H45_RS02650
uniprot id: A0A7T4K5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

33037:I6H45 RS03175
gene id: 33037:I6H45_RS03175
uniprot id: A0A7T4F231
names: Similarity
messages: Belongs to the thioesterase family.

33037:I6H45 RS04975
gene id: 33037:I6H45_RS04975
uniprot id: A0A7T4K4P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

33037:I6H45 RS02930
gene id: 33037:I6H45_RS02930
uniprot id: A0A7T4F207
names: Similarity
messages: Belongs to the type IA topoisomerase family.

33037:I6H45 RS04195
gene id: 33037:I6H45_RS04195
uniprot id: A0A7T4F2T3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

33037:I6H45 RS02635
gene id: 33037:I6H45_RS02635
uniprot id: A0A7T4F1S0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

33037:I6H45 RS01750
gene id: 33037:I6H45_RS01750
uniprot id: A0A6N2RBE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

33037:I6H45 RS07470
gene id: 33037:I6H45_RS07470
uniprot id: A0A7T4F0S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

33037:I6H45 RS00465
gene id: 33037:I6H45_RS00465
uniprot id: A0A7T4K5C0
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

33037:I6H45 RS04060
gene id: 33037:I6H45_RS04060
uniprot id: A0A7T4F2N8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02255
gene id: 33037:I6H45_RS02255
uniprot id: A0A7T4K5S0
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

33037:I6H45 RS05100
gene id: 33037:I6H45_RS05100
uniprot id: A0A7T4EZH5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

33037:I6H45 RS03860
gene id: 33037:I6H45_RS03860
uniprot id: A0A7T4K5V6
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07390
gene id: 33037:I6H45_RS07390
uniprot id: A0A7T4F0R8
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

33037:I6H45 RS02140
gene id: 33037:I6H45_RS02140
uniprot id: A0A7T4F1L3
names: Similarity
messages: Belongs to the leucine-binding protein family.

33037:I6H45 RS01725
gene id: 33037:I6H45_RS01725
uniprot id: A0A6N2R8A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

33037:I6H45 RS02810
gene id: 33037:I6H45_RS02810
uniprot id: A0A7T4K5Z2
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS07805
gene id: 33037:I6H45_RS07805
uniprot id: A0A7T4F0F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS08690
gene id: 33037:I6H45_RS08690
uniprot id: A0A7T4K5C9
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS01740
gene id: 33037:I6H45_RS01740
uniprot id: A0A6N2R8S2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

33037:I6H45 RS07680
gene id: 33037:I6H45_RS07680
uniprot id: A0A7T4K566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

33037:I6H45 RS03885
gene id: 33037:I6H45_RS03885
uniprot id: A0A7T4F281
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02465
gene id: 33037:I6H45_RS02465
uniprot id: A0A7T4F1Q0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

33037:I6H45 RS04980
gene id: 33037:I6H45_RS04980
uniprot id: A0A7T4K4J5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

33037:I6H45 RS03640
gene id: 33037:I6H45_RS03640
uniprot id: A0A7T4F268
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

33037:I6H45 RS04990
gene id: 33037:I6H45_RS04990
uniprot id: A0A6N2RPY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

33037:I6H45 RS07245
gene id: 33037:I6H45_RS07245
uniprot id: A0A7T4F0A0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPP isomerase type 2 family.
messages: Cytoplasm
messages: Homooctamer. Dimer of tetramers.
messages: Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

33037:I6H45 RS05415
gene id: 33037:I6H45_RS05415
uniprot id: A0A7T4EZP0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

33037:I6H45 RS06485
gene id: 33037:I6H45_RS06485
uniprot id: A0A7T4K4R3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

33037:I6H45 RS08560
gene id: 33037:I6H45_RS08560
uniprot id: A0A7T4K568
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.

33037:I6H45 RS02665
gene id: 33037:I6H45_RS02665
uniprot id: A0A6N2TRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

33037:I6H45 RS02100
gene id: 33037:I6H45_RS02100
uniprot id: A0A7T4K5H9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

33037:I6H45 RS06010
gene id: 33037:I6H45_RS06010
uniprot id: A0A7T4K4Q5
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

33037:I6H45 RS00420
gene id: 33037:I6H45_RS00420
uniprot id: A0A7T4F112
names: Cofactor
messages: Binds 1 zinc ion per subunit.

33037:I6H45 RS03570
gene id: 33037:I6H45_RS03570
uniprot id: A0A7T4F272
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

33037:I6H45 RS03520
gene id: 33037:I6H45_RS03520
uniprot id: A0A7T4K5W6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

33037:I6H45 RS02150
gene id: 33037:I6H45_RS02150
uniprot id: A0A6N2RM63
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS05610
gene id: 33037:I6H45_RS05610
uniprot id: A0A7T4K4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

33037:I6H45 RS02570
gene id: 33037:I6H45_RS02570
uniprot id: A0A7T4K5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

33037:I6H45 RS05835
gene id: 33037:I6H45_RS05835
uniprot id: A0A7T4K4P9
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08460
gene id: 33037:I6H45_RS08460
uniprot id: A0A7T4F126
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.

33037:I6H45 RS08695
gene id: 33037:I6H45_RS08695
uniprot id: A0A7T4K556
names: Similarity
messages: Belongs to the peptidase S49 family.

33037:I6H45 RS08685
gene id: 33037:I6H45_RS08685
uniprot id: A0A7T4F152
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS00035
gene id: 33037:I6H45_RS00035
uniprot id: A0A7T4F0V4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

33037:I6H45 RS07705
gene id: 33037:I6H45_RS07705
uniprot id: A0A7T4F0N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

33037:I6H45 RS01080
gene id: 33037:I6H45_RS01080
uniprot id: A0A7T4F181
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

33037:I6H45 RS05385
gene id: 33037:I6H45_RS05385
uniprot id: A0A6N2U303
names: Cofactor
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
messages: Binds 3 [4Fe-4S] clusters per subunit.

33037:I6H45 RS02095
gene id: 33037:I6H45_RS02095
uniprot id: A0A7T4K5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyl-CoA hydrolase/transferase family.
messages: Coenzyme A-transferase that converts butyrate to butyryl-CoA.
messages: Cytoplasm

33037:I6H45 RS07795
gene id: 33037:I6H45_RS07795
uniprot id: A0A7T4F0G6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

33037:I6H45 RS03680
gene id: 33037:I6H45_RS03680
uniprot id: A0A6N2RUI4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

33037:I6H45 RS01295
gene id: 33037:I6H45_RS01295
uniprot id: A0A7T4F1A0
names: Similarity
messages: Belongs to the BMP lipoprotein family.

33037:I6H45 RS06510
gene id: 33037:I6H45_RS06510
uniprot id: A0A7T4F0F6
names: Similarity
messages: Belongs to the DprA/Smf family.

33037:I6H45 RS08365
gene id: 33037:I6H45_RS08365
uniprot id: A0A7T4F0N1
names: Similarity
names: Subunit
messages: Belongs to the UPF0210 family.
messages: Homodimer.

33037:I6H45 RS07175
gene id: 33037:I6H45_RS07175
uniprot id: A0A7T4F076
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

33037:I6H45 RS00745
gene id: 33037:I6H45_RS00745
uniprot id: A0A7T4F199
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

33037:I6H45 RS06400
gene id: 33037:I6H45_RS06400
uniprot id: A0A7T4K4S9
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

33037:I6H45 RS01010
gene id: 33037:I6H45_RS01010
uniprot id: A0A6N2S4V9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

33037:I6H45 RS01445
gene id: 33037:I6H45_RS01445
uniprot id: A0A6N2RFQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

33037:I6H45 RS04825
gene id: 33037:I6H45_RS04825
uniprot id: A0A7T4K4I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Catalyzes the methylation of 5-hydroxyuridine (ho5U) to form 5-methoxyuridine (mo5U) at position 34 in tRNAs.
messages: Homodimer.

33037:I6H45 RS00300
gene id: 33037:I6H45_RS00300
uniprot id: A0A6N2S377
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS03240
gene id: 33037:I6H45_RS03240
uniprot id: A0A7T4F1Z5
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02690
gene id: 33037:I6H45_RS02690
uniprot id: A0A6N2TNI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

33037:I6H45 RS01460
gene id: 33037:I6H45_RS01460
uniprot id: A0A7T4K5M8
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS04780
gene id: 33037:I6H45_RS04780
uniprot id: A0A6N2U974
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

33037:I6H45 RS07855
gene id: 33037:I6H45_RS07855
uniprot id: A0A7T4F2J2
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

33037:I6H45 RS05315
gene id: 33037:I6H45_RS05315
uniprot id: A0A6N2U289
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

33037:I6H45 RS05205
gene id: 33037:I6H45_RS05205
uniprot id: A0A7T4K4K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

33037:I6H45 RS00430
gene id: 33037:I6H45_RS00430
uniprot id: A0A7T4F198
names: Similarity
messages: Belongs to the diacylglycerol/lipid kinase family.

33037:I6H45 RS01680
gene id: 33037:I6H45_RS01680
uniprot id: A0A6N2RB73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

33037:I6H45 RS01235
gene id: 33037:I6H45_RS01235
uniprot id: A0A7T4K5D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS04260
gene id: 33037:I6H45_RS04260
uniprot id: A0A7T4K5X9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

33037:I6H45 RS03960
gene id: 33037:I6H45_RS03960
uniprot id: A0A7T4F291
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

33037:I6H45 RS04795
gene id: 33037:I6H45_RS04795
uniprot id: A0A7T4EZK8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

33037:I6H45 RS08780
gene id: 33037:I6H45_RS08780
uniprot id: A0A7T4K544
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

33037:I6H45 RS02305
gene id: 33037:I6H45_RS02305
uniprot id: A0A7T4F1N0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS06040
gene id: 33037:I6H45_RS06040
uniprot id: A0A7T4EZV0
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS02005
gene id: 33037:I6H45_RS02005
uniprot id: A0A7T4F1J0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

33037:I6H45 RS00105
gene id: 33037:I6H45_RS00105
uniprot id: A0A6N2RXC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS07590
gene id: 33037:I6H45_RS07590
uniprot id: A0A7T4F0J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

33037:I6H45 RS04970
gene id: 33037:I6H45_RS04970
uniprot id: A0A7T4EZV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

33037:I6H45 RS07375
gene id: 33037:I6H45_RS07375
uniprot id: A0A7T4K4X9
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

33037:I6H45 RS04410
gene id: 33037:I6H45_RS04410
uniprot id: A0A7T4K687
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

33037:I6H45 RS08140
gene id: 33037:I6H45_RS08140
uniprot id: A0A7T4F0K7
names: Subcellular Location Annotation
messages: Membrane

33037:I6H45 RS08245
gene id: 33037:I6H45_RS08245
uniprot id: A0A7T4K524
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm