32536:LOC106986633
gene id: 32536:LOC106986633
uniprot id: A0A6J0A829
names: Subcellular Location Annotation
messages: Secreted

32536:LYVE1
gene id: 32536:LYVE1
uniprot id: A0A6I9ZLH7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ATP5IF1
gene id: 32536:ATP5IF1
uniprot id: A0A6I9ZXF4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase inhibitor family.
messages: Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase.
messages: Forms an alpha-helical dimer with monomers associated via an antiparallel alpha-helical coiled coil, leaving each N-terminal inhibitory region accessible for interaction with an F1 catalytic domain. The inhibitory N-terminal region binds the alpha(ADP-bound)-beta(ADP-bound) (ATP5F1A-ATP5F1B) interface of F1-ATPase, and also contact the central gamma subunit (ATP5F1C). This dimeric state is favored by pH values below 7.0, and at higher values the dimers associate to form inactive homotetramer, where the inhibitory region is occluded, masking its inhibitory activity.
messages: Homodimer; represents the active form and is present at a pH value below 6.5. Homotetramer; represents the inactive form and is present at a pH value above 7.0.
messages: Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing fech to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme.
messages: Mitochondrion

32536:PDE6D
gene id: 32536:PDE6D
uniprot id: A0A6J1Z750
names: Similarity
messages: Belongs to the PDE6D/unc-119 family.

32536:SLC25A16
gene id: 32536:SLC25A16
uniprot id: A0A6J1ZNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:CRHR1
gene id: 32536:CRHR1
uniprot id: A0A6J1YUQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Membrane

32536:RALYL
gene id: 32536:RALYL
uniprot id: A0A6J1ZRE3
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

32536:EPHA1
gene id: 32536:EPHA1
uniprot id: A0A6J2ASD5
uniprot id: A0A6J2ASV3
names: Subcellular Location Annotation
messages: Membrane

32536:VWC2
gene id: 32536:VWC2
uniprot id: A0A6J1YBE4
names: Subcellular Location Annotation
messages: Synapse

32536:AASS
gene id: 32536:AASS
uniprot id: A0A6I9ZNH3
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

32536:RPL8
gene id: 32536:RPL8
uniprot id: A0A6J0A8E8
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

32536:LRP3
gene id: 32536:LRP3
uniprot id: A0A6J1Y6Q7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DOCK3
gene id: 32536:DOCK3
uniprot id: A0A6J1XQ15
uniprot id: A0A6J1XQ16
uniprot id: A0A6J1XQ21
uniprot id: A0A6J1XQ22
uniprot id: A0A6J1XQ27
uniprot id: A0A6J1XQ91
uniprot id: A0A6J1XQA0
uniprot id: A0A6J1XQA2
uniprot id: A0A6J1XQB2
uniprot id: A0A6J1XQB6
names: Similarity
messages: Belongs to the DOCK family.

32536:STX12
gene id: 32536:STX12
uniprot id: A0A6I9ZXQ9
names: Similarity
messages: Belongs to the syntaxin family.

32536:METTL6
gene id: 32536:METTL6
uniprot id: A0A6J1ZJJ5
uniprot id: A0A6J1ZJW6
uniprot id: A0A6J1ZJX1
uniprot id: A0A6J1ZN96
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

32536:LOC106986497
gene id: 32536:LOC106986497
uniprot id: A0A6J0A510
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:FIP1L1
gene id: 32536:FIP1L1
uniprot id: A0A6J1Z565
uniprot id: A0A6J1Z573
uniprot id: A0A6J1Z5B6
uniprot id: A0A6J1Z5M3
uniprot id: A0A6J1Z5N6
uniprot id: A0A6J1Z5P2
uniprot id: A0A6J1Z5Q9
uniprot id: A0A6J1Z6L7
uniprot id: A0A6J1Z6N0
uniprot id: A0A6J1Z754
uniprot id: A0A6J1Z794
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

32536:LOC106976623
gene id: 32536:LOC106976623
uniprot id: A0A6I9ZWL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ODAD4
gene id: 32536:ODAD4
uniprot id: A0A6I9ZL03
names: Subcellular Location Annotation
messages: cilium axoneme

32536:MED7
gene id: 32536:MED7
uniprot id: A0A6I9ZDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

32536:ARHGEF7
gene id: 32536:ARHGEF7
uniprot id: A0A6J1ZV48
uniprot id: A0A6J1ZV52
uniprot id: A0A6J1ZY38
uniprot id: A0A6J1ZY42
names: Subcellular Location Annotation
messages: lamellipodium

32536:SLC6A3
gene id: 32536:SLC6A3
uniprot id: A0A6J2AJW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

32536:ARHGAP33
gene id: 32536:ARHGAP33
uniprot id: A0A6J1Y697
uniprot id: A0A6J1Y839
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

32536:KCNJ14
gene id: 32536:KCNJ14
uniprot id: A0A6J1XMK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

32536:ZIC4
gene id: 32536:ZIC4
uniprot id: A0A6J1ZIV8
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

32536:LOC106989354
gene id: 32536:LOC106989354
uniprot id: A0A6J1YC07
names: Similarity
messages: Belongs to the peptidase C2 family.

32536:NDUFC1
gene id: 32536:NDUFC1
uniprot id: A0A6J1ZXH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

32536:CCL21
gene id: 32536:CCL21
uniprot id: A0A6I9ZUT5
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

32536:LOC106966597
gene id: 32536:LOC106966597
uniprot id: A0A6I9ZFA1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

32536:LOC113598493
gene id: 32536:LOC113598493
uniprot id: A0A6J1Z3U0
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

32536:MFSD1
gene id: 32536:MFSD1
uniprot id: A0A6I9ZLJ5
names: Subcellular Location Annotation
messages: Membrane

32536:CKM
gene id: 32536:CKM
uniprot id: A0A6I9ZNW8
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

32536:OPALIN
gene id: 32536:OPALIN
uniprot id: A0A6J0A5U5
uniprot id: A0A6J1ZM04
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

32536:FAM53B
gene id: 32536:FAM53B
uniprot id: A0A6J1ZR81
names: Similarity
messages: Belongs to the FAM53 family.

32536:MECP2
gene id: 32536:MECP2
uniprot id: A0A6J1YYI1
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

32536:USP7
gene id: 32536:USP7
uniprot id: A0A6J1Y2W9
uniprot id: A0A6J1Y464
names: Similarity
messages: Belongs to the peptidase C19 family.

32536:GMFG
gene id: 32536:GMFG
uniprot id: A0A6J0A0L8
uniprot id: A0A6J1Y730
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

32536:UNC45B
gene id: 32536:UNC45B
uniprot id: A0A6J0A1G9
names: Subcellular Location Annotation
messages: A band
messages: Z line
messages: perinuclear region

32536:BMP7
gene id: 32536:BMP7
uniprot id: A0A6J1YCA9
names: Similarity
messages: Belongs to the TGF-beta family.

32536:KRT40
gene id: 32536:KRT40
uniprot id: A0A6J0AB27
names: Similarity
messages: Belongs to the intermediate filament family.

32536:C4BPB
gene id: 32536:C4BPB
uniprot id: A0A6J0A2I4
uniprot id: A0A6J0A3H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106978793
gene id: 32536:LOC106978793
uniprot id: A0A6J1Y2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TRIM21
gene id: 32536:TRIM21
uniprot id: A0A6I9ZG30
names: Subcellular Location Annotation
messages: Cytoplasm

32536:PRPF31
gene id: 32536:PRPF31
uniprot id: A0A6J1XL01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP31 family.
messages: Cajal body

32536:LOC113599166
gene id: 32536:LOC113599166
uniprot id: A0A6J1ZBC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

32536:VPS35L
gene id: 32536:VPS35L
uniprot id: A0A6J1Y206
uniprot id: A0A6J1Y288
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

32536:MPP1
gene id: 32536:MPP1
uniprot id: A0A6J1YY90
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: stereocilium

32536:DHX8
gene id: 32536:DHX8
uniprot id: A0A6J0A7T3
names: Subcellular Location Annotation
messages: Nucleus

32536:ABCA3
gene id: 32536:ABCA3
uniprot id: A0A6J1Y4W7
names: Subcellular Location Annotation
messages: Membrane

32536:VEPH1
gene id: 32536:VEPH1
uniprot id: A0A6I9ZGN8
uniprot id: A0A6J1ZJT6
uniprot id: A0A6J1ZKZ7
names: Similarity
messages: Belongs to the MELT/VEPH family.

32536:LOC106965983
gene id: 32536:LOC106965983
uniprot id: A0A6I9ZEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LHFPL3
gene id: 32536:LHFPL3
uniprot id: A0A6J2AC54
uniprot id: A0A6J2AGI7
names: Subcellular Location Annotation
messages: Membrane

32536:AVL9
gene id: 32536:AVL9
uniprot id: A0A6J2AR45
names: Subcellular Location Annotation
messages: Recycling endosome

32536:B4GALT2
gene id: 32536:B4GALT2
uniprot id: A0A6I9ZMM6
uniprot id: A0A6J1ZFW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

32536:LOC106987491
gene id: 32536:LOC106987491
uniprot id: A0A6J0A993
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

32536:MRPL52
gene id: 32536:MRPL52
uniprot id: A0A6J0A7J3
uniprot id: A0A6J0AA58
uniprot id: A0A6J0AA69
uniprot id: A0A6J0AB78
uniprot id: A0A6J1ZUV1
uniprot id: A0A6J1ZVM2
uniprot id: A0A6J1ZYK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

32536:RHOT2
gene id: 32536:RHOT2
uniprot id: A0A6J1Y3L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

32536:LOC106976594
gene id: 32536:LOC106976594
uniprot id: A0A6I9ZW26
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:VPS4A
gene id: 32536:VPS4A
uniprot id: A0A6J2APF8
uniprot id: A0A6J2ARE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

32536:OCM2
gene id: 32536:OCM2
uniprot id: A0A6I9ZYL6
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

32536:B3GAT2
gene id: 32536:B3GAT2
uniprot id: A0A6J1Z937
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:RPS27A
gene id: 32536:RPS27A
uniprot id: A0A6I9ZT97
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

32536:PRKACA
gene id: 32536:PRKACA
uniprot id: A0A6J0A727
uniprot id: A0A6J1YLB0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

32536:LOC106967157
gene id: 32536:LOC106967157
uniprot id: A0A6J1ZLK6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

32536:PPP2R2C
gene id: 32536:PPP2R2C
uniprot id: A0A6J2AT78
uniprot id: A0A6J2AWJ7
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

32536:FXYD3
gene id: 32536:FXYD3
uniprot id: A0A6J1Y8I2
names: Similarity
messages: Belongs to the FXYD family.

32536:BPI
gene id: 32536:BPI
uniprot id: A0A6J2A8L0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

32536:RPL7L1
gene id: 32536:RPL7L1
uniprot id: A0A6I9ZMY2
uniprot id: A0A6I9ZRA3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

32536:CACNB1
gene id: 32536:CACNB1
uniprot id: A0A6J1XB38
uniprot id: A0A6J1XB46
uniprot id: A0A6J1XB48
uniprot id: A0A6J1XB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

32536:DOLPP1
gene id: 32536:DOLPP1
uniprot id: A0A6J1XFA4
uniprot id: A0A6J1XFA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

32536:GPT
gene id: 32536:GPT
uniprot id: A0A6J1ZPE9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

32536:WDR12
gene id: 32536:WDR12
uniprot id: A0A6I9ZYP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

32536:SF1
gene id: 32536:SF1
uniprot id: A0A6J1Y827
uniprot id: A0A6J1Y833
uniprot id: A0A6J1Y837
uniprot id: A0A6J1Y838
uniprot id: A0A6J1Y8T5
uniprot id: A0A6J1Y8U5
uniprot id: A0A6J1Y9A0
uniprot id: A0A6J1Y9V3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

32536:LGMN
gene id: 32536:LGMN
uniprot id: A0A6J0A1A9
names: Similarity
messages: Belongs to the peptidase C13 family.

32536:CDC42BPB
gene id: 32536:CDC42BPB
uniprot id: A0A6J1ZYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

32536:FUZ
gene id: 32536:FUZ
uniprot id: A0A6J1XN73
uniprot id: A0A6J1XN81
uniprot id: A0A6J1XNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fuzzy family.
messages: cytoskeleton

32536:ASF1B
gene id: 32536:ASF1B
uniprot id: A0A6J1YMH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

32536:MED17
gene id: 32536:MED17
uniprot id: A0A6J0A6J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:PTPA
gene id: 32536:PTPA
uniprot id: A0A6J1XFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:MRPL42
gene id: 32536:MRPL42
uniprot id: A0A6I9ZM00
uniprot id: A0A6I9ZNM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

32536:FAM174A
gene id: 32536:FAM174A
uniprot id: A0A6J1XKS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

32536:STAM2
gene id: 32536:STAM2
uniprot id: A0A6I9ZQT4
uniprot id: A0A6I9ZS37
uniprot id: A0A6I9ZU63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

32536:HSPB2
gene id: 32536:HSPB2
uniprot id: A0A6J0A2F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: Nucleus

32536:SCAND1
gene id: 32536:SCAND1
uniprot id: A0A6J2A7H0
names: Subcellular Location Annotation
messages: Nucleus

32536:AQR
gene id: 32536:AQR
uniprot id: A0A6I9ZM32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWF11 family.
messages: Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
messages: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
messages: Nucleus

32536:OST4
gene id: 32536:OST4
uniprot id: A0A6J1X6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:ZSCAN26
gene id: 32536:ZSCAN26
uniprot id: A0A6J1YSZ4
names: Subcellular Location Annotation
messages: Nucleus

32536:PLPPR5
gene id: 32536:PLPPR5
uniprot id: A0A6J1Z9U8
uniprot id: A0A6J1ZB69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

32536:ATP1A1
gene id: 32536:ATP1A1
uniprot id: A0A6J1ZIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

32536:ETV6
gene id: 32536:ETV6
uniprot id: A0A6J1XFW1
uniprot id: A0A6J1XFW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:PRKCE
gene id: 32536:PRKCE
uniprot id: A0A6J2AEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

32536:BEX4
gene id: 32536:BEX4
uniprot id: A0A6J1YY36
names: Similarity
messages: Belongs to the BEX family.

32536:LOC106986236
gene id: 32536:LOC106986236
uniprot id: A0A6J0A4Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106966030
gene id: 32536:LOC106966030
uniprot id: A0A6I9ZCZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SIKE1
gene id: 32536:SIKE1
uniprot id: A0A6J1ZA21
names: Similarity
messages: Belongs to the SIKE family.

32536:CA1H5orf63
gene id: 32536:CA1H5orf63
uniprot id: A0A6J2ARE1
uniprot id: A0A6J2ATD3
names: Similarity
messages: Belongs to the glutaredoxin family.

32536:LOC106988647
gene id: 32536:LOC106988647
uniprot id: A0A6J0A7Z3
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:RBM46
gene id: 32536:RBM46
uniprot id: A0A6J0A3Q4
names: Subcellular Location Annotation
messages: Cytoplasm

32536:ISL2
gene id: 32536:ISL2
uniprot id: A0A6J2A1P2
names: Subcellular Location Annotation
messages: Nucleus

32536:C5AR2
gene id: 32536:C5AR2
uniprot id: A0A6J1XMF8
uniprot id: A0A6J1XMM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

32536:TANGO6
gene id: 32536:TANGO6
uniprot id: A0A6I9ZPW2
names: Similarity
messages: Belongs to the Tango6 family.

32536:LOC106987143
gene id: 32536:LOC106987143
uniprot id: A0A6J0A8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TBX6
gene id: 32536:TBX6
uniprot id: A0A6J1YTK9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:TRIAP1
gene id: 32536:TRIAP1
uniprot id: A0A6I9ZJS0
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

32536:HS6ST1
gene id: 32536:HS6ST1
uniprot id: A0A6J1Z549
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

32536:FHIP2B
gene id: 32536:FHIP2B
uniprot id: A0A6J2ATQ0
uniprot id: A0A6J2AV95
names: Similarity
messages: Belongs to the FHIP family.

32536:SEC23A
gene id: 32536:SEC23A
uniprot id: A0A6J1ZWB1
uniprot id: A0A6J1ZXV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

32536:CLDN12
gene id: 32536:CLDN12
uniprot id: A0A6J0A455
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

32536:FXYD1
gene id: 32536:FXYD1
uniprot id: A0A6I9ZTH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the FXYD family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: T-tubule
messages: caveola
messages: sarcolemma

32536:CES4A
gene id: 32536:CES4A
uniprot id: A0A6I9ZPG4
uniprot id: A0A6J2APJ3
uniprot id: A0A6J2APJ9
uniprot id: A0A6J2AR17
uniprot id: A0A6J2AT97
uniprot id: A0A6J2ATR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

32536:CORO1C
gene id: 32536:CORO1C
uniprot id: A0A6J1Y564
uniprot id: A0A6J1Y662
names: Similarity
messages: Belongs to the WD repeat coronin family.

32536:LOC106984034
gene id: 32536:LOC106984034
uniprot id: A0A6J0A2A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GUSB
gene id: 32536:GUSB
uniprot id: A0A6I9ZQW5
uniprot id: A0A6J1XYK8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

32536:LOC106981761
gene id: 32536:LOC106981761
uniprot id: A0A6J1ZCK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

32536:TALDO1
gene id: 32536:TALDO1
uniprot id: A0A6J1YQ25
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

32536:JAKMIP2
gene id: 32536:JAKMIP2
uniprot id: A0A6J1XZ71
uniprot id: A0A6J1XZC8
uniprot id: A0A6J1XZQ5
names: Similarity
messages: Belongs to the JAKMIP family.

32536:CASR
gene id: 32536:CASR
uniprot id: A0A6J1ZH24
uniprot id: A0A6J1ZKH9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:TUBA8
gene id: 32536:TUBA8
uniprot id: A0A6I9ZJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

32536:TLR1
gene id: 32536:TLR1
uniprot id: A0A6J0A002
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane
messages: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

32536:NHSL2
gene id: 32536:NHSL2
uniprot id: A0A6J1YW77
names: Similarity
messages: Belongs to the NHS family.

32536:MYG1
gene id: 32536:MYG1
uniprot id: A0A6J1XHW1
uniprot id: A0A6J1XHW4
uniprot id: A0A6J1XHY1
names: Similarity
messages: Belongs to the MYG1 family.

32536:SMAD6
gene id: 32536:SMAD6
uniprot id: A0A6J2A1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

32536:CC1H1orf52
gene id: 32536:CC1H1orf52
uniprot id: A0A6I9ZSG0
names: Similarity
messages: Belongs to the UPF0690 family.

32536:CCBE1
gene id: 32536:CCBE1
uniprot id: A0A6J2A520
uniprot id: A0A6J2A602
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ARSA
gene id: 32536:ARSA
uniprot id: A0A6J2A8F7
uniprot id: A0A6J2ACQ3
names: Similarity
messages: Belongs to the sulfatase family.

32536:POGLUT3
gene id: 32536:POGLUT3
uniprot id: A0A6J1XI91
names: Similarity
messages: Belongs to the KDELC family.

32536:CORO2A
gene id: 32536:CORO2A
uniprot id: A0A6J1XRZ5
names: Similarity
messages: Belongs to the WD repeat coronin family.

32536:LOC106980214
gene id: 32536:LOC106980214
uniprot id: A0A6J0A1G4
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

32536:GLUL
gene id: 32536:GLUL
uniprot id: A0A6J2ANS6
uniprot id: A0A6J2AP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome
messages: Mitochondrion

32536:TBCB
gene id: 32536:TBCB
uniprot id: A0A6I9ZQD0
uniprot id: A0A6J1Y6N1
names: Similarity
messages: Belongs to the TBCB family.

32536:EIF2B4
gene id: 32536:EIF2B4
uniprot id: A0A6I9ZEC3
uniprot id: A0A6I9ZHB6
uniprot id: A0A6J1X6H3
uniprot id: A0A6J1X780
uniprot id: A0A6J1XA07
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

32536:ANKRD13A
gene id: 32536:ANKRD13A
uniprot id: A0A6J1Y6E0
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

32536:BGN
gene id: 32536:BGN
uniprot id: A0A6J1YWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: May be involved in collagen fiber assembly.
messages: extracellular matrix

32536:AP4B1
gene id: 32536:AP4B1
uniprot id: A0A6J1ZA48
uniprot id: A0A6J1ZAK9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

32536:GJB6
gene id: 32536:GJB6
uniprot id: A0A6J0A0Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

32536:PPIB
gene id: 32536:PPIB
uniprot id: A0A6J0A6B1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:TEX261
gene id: 32536:TEX261
uniprot id: A0A6J2AE14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

32536:PDCD10
gene id: 32536:PDCD10
uniprot id: A0A6J0ABW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

32536:ACOX2
gene id: 32536:ACOX2
uniprot id: A0A6I9ZFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

32536:AK5
gene id: 32536:AK5
uniprot id: A0A6J1ZC46
uniprot id: A0A6J1ZD09
uniprot id: A0A6J1ZE69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

32536:HTR1D
gene id: 32536:HTR1D
uniprot id: A0A6J1ZGZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

32536:SPIN4
gene id: 32536:SPIN4
uniprot id: A0A6J0A6E8
names: Similarity
messages: Belongs to the SPIN/STSY family.

32536:NOP10
gene id: 32536:NOP10
uniprot id: A0A6I9ZM38
names: Similarity
messages: Belongs to the NOP10 family.

32536:TLR4
gene id: 32536:TLR4
uniprot id: A0A6I9ZW49
uniprot id: A0A6J1XE48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

32536:FANCC
gene id: 32536:FANCC
uniprot id: A0A6J1YG77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

32536:PHLDA1
gene id: 32536:PHLDA1
uniprot id: A0A6I9ZIB0
names: Subcellular Location Annotation
messages: Cytoplasm

32536:NKD2
gene id: 32536:NKD2
uniprot id: A0A6J2AH48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

32536:GDAP2
gene id: 32536:GDAP2
uniprot id: A0A6I9ZYX3
names: Similarity
messages: Belongs to the GDAP2 family.

32536:TM2D3
gene id: 32536:TM2D3
uniprot id: A0A6J2A2Q8
names: Subcellular Location Annotation
messages: Membrane

32536:MCHR2
gene id: 32536:MCHR2
uniprot id: A0A6I9ZUW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:TASP1
gene id: 32536:TASP1
uniprot id: A0A6J0A2R6
uniprot id: A0A6J2AA15
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

32536:LOC106967516
gene id: 32536:LOC106967516
uniprot id: A0A6I9ZF73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:FGD2
gene id: 32536:FGD2
uniprot id: A0A6J1Z9B2
uniprot id: A0A6J1ZA61
names: Subcellular Location Annotation
messages: cytoskeleton

32536:DTX2
gene id: 32536:DTX2
uniprot id: A0A6I9ZYN5
uniprot id: A0A6J1XZ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

32536:GTF2H5
gene id: 32536:GTF2H5
uniprot id: A0A6J0A0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

32536:KRT7
gene id: 32536:KRT7
uniprot id: A0A6J1XHR5
names: Similarity
messages: Belongs to the intermediate filament family.

32536:TBX19
gene id: 32536:TBX19
uniprot id: A0A6J1YAI6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:TRPM7
gene id: 32536:TRPM7
uniprot id: A0A6I9ZI38
uniprot id: A0A6J2A2Q3
uniprot id: A0A6J2A3S8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

32536:GTPBP4
gene id: 32536:GTPBP4
uniprot id: A0A6I9ZXW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

32536:NHP2
gene id: 32536:NHP2
uniprot id: A0A6J2ATN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

32536:NSUN7
gene id: 32536:NSUN7
uniprot id: A0A6J0A7H1
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:OCIAD1
gene id: 32536:OCIAD1
uniprot id: A0A6I9ZP47
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

32536:SLC41A3
gene id: 32536:SLC41A3
uniprot id: A0A6J1YC16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

32536:DNAJB12
gene id: 32536:DNAJB12
uniprot id: A0A6I9ZI07
uniprot id: A0A6I9ZI20
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:CA7
gene id: 32536:CA7
uniprot id: A0A6J2AT59
uniprot id: A0A6J2ATN0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

32536:STX6
gene id: 32536:STX6
uniprot id: A0A6I9ZCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Golgi apparatus membrane

32536:GDF10
gene id: 32536:GDF10
uniprot id: A0A6J0A969
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

32536:IL2
gene id: 32536:IL2
uniprot id: A0A6I9ZWY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-2 family.
messages: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
messages: Secreted

32536:ZNF503
gene id: 32536:ZNF503
uniprot id: A0A6J1ZKW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

32536:GPRIN2
gene id: 32536:GPRIN2
uniprot id: A0A6J1ZNS0
names: Function
messages: May be involved in neurite outgrowth.

32536:TSC22D4
gene id: 32536:TSC22D4
uniprot id: A0A6J1XZR6
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

32536:UBE3A
gene id: 32536:UBE3A
uniprot id: A0A6I9ZFS5
uniprot id: A0A6I9ZIW2
uniprot id: A0A6J2A4P6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
messages: Nucleus

32536:PIK3IP1
gene id: 32536:PIK3IP1
uniprot id: A0A6J1YN94
uniprot id: A0A6J1YNB2
uniprot id: A0A6J1YR92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TYMS
gene id: 32536:TYMS
uniprot id: A0A6J2A3M6
names: Similarity
messages: Belongs to the thymidylate synthase family.

32536:HYLS1
gene id: 32536:HYLS1
uniprot id: A0A6I9ZUG5
uniprot id: A0A6J1XJN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HYLS1 family.
messages: centriole
messages: cilium

32536:TFIP11
gene id: 32536:TFIP11
uniprot id: A0A6J1YN43
uniprot id: A0A6J1YR18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

32536:SNTA1
gene id: 32536:SNTA1
uniprot id: A0A6J2A745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

32536:LOC113600099
gene id: 32536:LOC113600099
uniprot id: A0A6J1ZNM1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

32536:LOC106988066
gene id: 32536:LOC106988066
uniprot id: A0A6J1XU00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:MASP2
gene id: 32536:MASP2
uniprot id: A0A6J1ZFI4
uniprot id: A0A6J1ZFU7
uniprot id: A0A6J1ZIW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106972069
gene id: 32536:LOC106972069
uniprot id: A0A6J1XS29
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

32536:AFP
gene id: 32536:AFP
uniprot id: A0A6J0A3Q8
names: Subcellular Location Annotation
messages: Secreted

32536:RPTOR
gene id: 32536:RPTOR
uniprot id: A0A6J1YSC0
uniprot id: A0A6J1YSC6
uniprot id: A0A6J1YU61
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

32536:CD163
gene id: 32536:CD163
uniprot id: A0A6I9ZC09
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:USP22
gene id: 32536:USP22
uniprot id: A0A6J1YG91
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:KDELR2
gene id: 32536:KDELR2
uniprot id: A0A6J1XZI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PSME1
gene id: 32536:PSME1
uniprot id: A0A6J0A0C8
names: Similarity
messages: Belongs to the PA28 family.

32536:MOGAT3
gene id: 32536:MOGAT3
uniprot id: A0A6J1XZ78
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:FAM151B
gene id: 32536:FAM151B
uniprot id: A0A6I9ZLX6
uniprot id: A0A6J1XRA4
names: Similarity
messages: Belongs to the FAM151 family.

32536:SLC25A37
gene id: 32536:SLC25A37
uniprot id: A0A6J2ATI0
uniprot id: A0A6J2ATI4
uniprot id: A0A6J2AY86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:HIBADH
gene id: 32536:HIBADH
uniprot id: A0A6J2AQY8
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

32536:TBL1XR1
gene id: 32536:TBL1XR1
uniprot id: A0A6J1ZI75
uniprot id: A0A6J1ZLS3
names: Similarity
messages: Belongs to the WD repeat EBI family.

32536:GLCE
gene id: 32536:GLCE
uniprot id: A0A6J2A1X3
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

32536:ZHX2
gene id: 32536:ZHX2
uniprot id: A0A6J1ZUI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

32536:LIPI
gene id: 32536:LIPI
uniprot id: A0A6I9ZNF7
uniprot id: A0A6J2ATY3
uniprot id: A0A6J2AVI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

32536:NSMCE1
gene id: 32536:NSMCE1
uniprot id: A0A6J1YS67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus
messages: RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair.
messages: telomere

32536:SSTR3
gene id: 32536:SSTR3
uniprot id: A0A6J2ADK8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:GNG7
gene id: 32536:GNG7
uniprot id: A0A6J1YJ93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:SLCO1A2
gene id: 32536:SLCO1A2
uniprot id: A0A6I9ZTW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PITPNM2
gene id: 32536:PITPNM2
uniprot id: A0A6J1Y4N4
names: Similarity
messages: Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.

32536:TJAP1
gene id: 32536:TJAP1
uniprot id: A0A6J1Z7I6
names: Subcellular Location Annotation
messages: Membrane

32536:STIM1
gene id: 32536:STIM1
uniprot id: A0A6J1XSD9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:SLC6A13
gene id: 32536:SLC6A13
uniprot id: A0A6J2AK89
uniprot id: A0A6J2AK98
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

32536:RFFL
gene id: 32536:RFFL
uniprot id: A0A6I9ZMB2
uniprot id: A0A6I9ZNZ1
uniprot id: A0A6I9ZR78
uniprot id: A0A6J1XCK0
names: Subcellular Location Annotation
messages: Cell membrane

32536:NINJ2
gene id: 32536:NINJ2
uniprot id: A0A6I9ZC76
uniprot id: A0A6J2AK84
uniprot id: A0A6J2AMQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

32536:GNA14
gene id: 32536:GNA14
uniprot id: A0A6J1XW35
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

32536:ERC1
gene id: 32536:ERC1
uniprot id: A0A6J2AIE8
uniprot id: A0A6J2AK53
uniprot id: A0A6J2AMY8
names: Subcellular Location Annotation
messages: Cytoplasm

32536:EPHA7
gene id: 32536:EPHA7
uniprot id: A0A6I9ZIM2
uniprot id: A0A6I9ZK73
uniprot id: A0A6I9ZNT2
names: Subcellular Location Annotation
messages: Membrane

32536:PSMA3
gene id: 32536:PSMA3
uniprot id: A0A6I9ZNI8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

32536:LOC106982840
gene id: 32536:LOC106982840
uniprot id: A0A6J0A3J4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

32536:MAPKAPK2
gene id: 32536:MAPKAPK2
uniprot id: A0A6J2AKR4
uniprot id: A0A6J2APT3
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:PLOD2
gene id: 32536:PLOD2
uniprot id: A0A6J1ZIX6
uniprot id: A0A6J1ZJ99
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

32536:ZIC1
gene id: 32536:ZIC1
uniprot id: A0A6J1ZIV3
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

32536:CNN1
gene id: 32536:CNN1
uniprot id: A0A6J1YLK2
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

32536:COG7
gene id: 32536:COG7
uniprot id: A0A6J1Y1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:HOXB9
gene id: 32536:HOXB9
uniprot id: A0A6J1XBE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

32536:LOC106974253
gene id: 32536:LOC106974253
uniprot id: A0A6I9ZST1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

32536:LOC113596521
gene id: 32536:LOC113596521
uniprot id: A0A6J1YM47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

32536:CD40LG
gene id: 32536:CD40LG
uniprot id: A0A6J0A6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

32536:SMAD5
gene id: 32536:SMAD5
uniprot id: A0A6J0AB28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

32536:SGO2
gene id: 32536:SGO2
uniprot id: A0A6J1YZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

32536:MTMR1
gene id: 32536:MTMR1
uniprot id: A0A6J1YVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

32536:NME3
gene id: 32536:NME3
uniprot id: A0A6J1Y3G2
names: Similarity
messages: Belongs to the NDK family.

32536:PAQR9
gene id: 32536:PAQR9
uniprot id: A0A6J1ZK82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

32536:ITIH2
gene id: 32536:ITIH2
uniprot id: A0A6J0A2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

32536:ST6GALNAC2
gene id: 32536:ST6GALNAC2
uniprot id: A0A6J1YUY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:CSNK1G3
gene id: 32536:CSNK1G3
uniprot id: A0A6J2ARG3
uniprot id: A0A6J2ARW0
uniprot id: A0A6J2ARW7
uniprot id: A0A6J2ATF2
uniprot id: A0A6J2AVS3
uniprot id: A0A6J2AWG6
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

32536:LOC106986229
gene id: 32536:LOC106986229
uniprot id: A0A6J0A4N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NANOS1
gene id: 32536:NANOS1
uniprot id: A0A6J1ZS67
names: Similarity
messages: Belongs to the nanos family.

32536:FURIN
gene id: 32536:FURIN
uniprot id: A0A6J2A293
names: Similarity
messages: Belongs to the peptidase S8 family.

32536:SLC50A1
gene id: 32536:SLC50A1
uniprot id: A0A6J1YJ27
uniprot id: A0A6J1YJU6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWEET sugar transporter family.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates sugar transport across membranes.
messages: Membrane

32536:SERPINE1
gene id: 32536:SERPINE1
uniprot id: A0A6J0A7G5
names: Similarity
messages: Belongs to the serpin family.

32536:ORC6
gene id: 32536:ORC6
uniprot id: A0A6I9ZCY3
uniprot id: A0A6I9ZFZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

32536:MC2R
gene id: 32536:MC2R
uniprot id: A0A6I9ZWA2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

32536:SENP3
gene id: 32536:SENP3
uniprot id: A0A6J1YEH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

32536:PITHD1
gene id: 32536:PITHD1
uniprot id: A0A6J1ZGY2
uniprot id: A0A6J1ZHY4
names: Similarity
messages: Belongs to the PITHD1 family.

32536:USP15
gene id: 32536:USP15
uniprot id: A0A6I9ZZI1
uniprot id: A0A6J0A2N3
uniprot id: A0A6J2AB66
uniprot id: A0A6J2ABG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus

32536:LOC106976554
gene id: 32536:LOC106976554
uniprot id: A0A6I9ZWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GRHL2
gene id: 32536:GRHL2
uniprot id: A0A6J0A0B4
uniprot id: A0A6J1ZR74
uniprot id: A0A6J1ZUX0
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106973111
gene id: 32536:LOC106973111
uniprot id: A0A6J2AC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.

32536:PSKH2
gene id: 32536:PSKH2
uniprot id: A0A6I9ZTX9
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:PLG
gene id: 32536:PLG
uniprot id: A0A6J1Z7M9
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Converted into plasmin by plasminogen activators, both plasminogen and its activator being bound to fibrin.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.
messages: Secreted

32536:DYNLRB2
gene id: 32536:DYNLRB2
uniprot id: A0A6J2AU55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

32536:LOC106977797
gene id: 32536:LOC106977797
uniprot id: A0A6I9ZUJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GLO1
gene id: 32536:GLO1
uniprot id: A0A6I9ZRQ0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

32536:MRPL12
gene id: 32536:MRPL12
uniprot id: A0A6J1YWC8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

32536:PCOLCE
gene id: 32536:PCOLCE
uniprot id: A0A6J1XZA9
uniprot id: A0A6J1Y079
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:STING1
gene id: 32536:STING1
uniprot id: A0A6I9ZE74
uniprot id: A0A6I9ZFR0
uniprot id: A0A6I9ZIY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

32536:CCNY
gene id: 32536:CCNY
uniprot id: A0A6I9ZY09
uniprot id: A0A6J2AM73
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

32536:LOC106983332
gene id: 32536:LOC106983332
uniprot id: A0A6J1YG56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

32536:SKIL
gene id: 32536:SKIL
uniprot id: A0A6J1ZID0
names: Similarity
messages: Belongs to the SKI family.

32536:NPHS2
gene id: 32536:NPHS2
uniprot id: A0A6J2AP23
names: Similarity
messages: Belongs to the band 7/mec-2 family.

32536:RNF31
gene id: 32536:RNF31
uniprot id: A0A6J1ZXD3
uniprot id: A0A6J1ZYS2
names: Similarity
messages: Belongs to the RBR family.

32536:SSR2
gene id: 32536:SSR2
uniprot id: A0A6J1YGI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

32536:ACP7
gene id: 32536:ACP7
uniprot id: A0A6J1Y6R7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

32536:PTPN3
gene id: 32536:PTPN3
uniprot id: A0A6J1XDN2
uniprot id: A0A6J1XDP4
uniprot id: A0A6J1XDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: May act at junctions between the membrane and the cytoskeleton.
messages: cytoskeleton

32536:PRKCQ
gene id: 32536:PRKCQ
uniprot id: A0A6J2AH82
uniprot id: A0A6J2AL87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

32536:DYNC1I1
gene id: 32536:DYNC1I1
uniprot id: A0A6J2AGP3
names: Similarity
messages: Belongs to the dynein intermediate chain family.

32536:KIF20A
gene id: 32536:KIF20A
uniprot id: A0A6I9ZG65
uniprot id: A0A6I9ZJI0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:TUBA4A
gene id: 32536:TUBA4A
uniprot id: A0A6J1YN80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

32536:CEBPA
gene id: 32536:CEBPA
uniprot id: A0A6I9ZVG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

32536:CCT3
gene id: 32536:CCT3
uniprot id: A0A6I9ZZ19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

32536:LOC106967445
gene id: 32536:LOC106967445
uniprot id: A0A6J1Z0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

32536:VAT1
gene id: 32536:VAT1
uniprot id: A0A6J1YIE3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

32536:LZIC
gene id: 32536:LZIC
uniprot id: A0A6J0A374
uniprot id: A0A6J0A710
names: Similarity
messages: Belongs to the CTNNBIP1 family.

32536:RBM48
gene id: 32536:RBM48
uniprot id: A0A6I9ZH69
names: Function
names: Similarity
names: Subunit
messages: As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
messages: Belongs to the RBM48 family.
messages: Component of the minor spliceosome. Within this complex, interacts with ARMC7 and PRPF8/PRP8.

32536:NPC2
gene id: 32536:NPC2
uniprot id: A0A6I9ZTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted

32536:NPM2
gene id: 32536:NPM2
uniprot id: A0A6I9ZZ39
names: Similarity
messages: Belongs to the nucleoplasmin family.

32536:TMEM9
gene id: 32536:TMEM9
uniprot id: A0A6J2AKB5
uniprot id: A0A6J2APZ1
names: Similarity
messages: Belongs to the TMEM9 family.

32536:RXRB
gene id: 32536:RXRB
uniprot id: A0A6J1Z8G5
uniprot id: A0A6J1ZAN0
uniprot id: A0A6J1ZBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Nucleus

32536:MYCBP
gene id: 32536:MYCBP
uniprot id: A0A6J1ZED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

32536:LOC106966705
gene id: 32536:LOC106966705
uniprot id: A0A6I9ZDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TRPM8
gene id: 32536:TRPM8
uniprot id: A0A6J1YF88
names: Subcellular Location Annotation
messages: Membrane

32536:PSPH
gene id: 32536:PSPH
uniprot id: A0A6I9ZQW0
uniprot id: A0A6I9ZRT7
uniprot id: A0A6J1XZG3
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

32536:BTK
gene id: 32536:BTK
uniprot id: A0A6J1YZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:NRP2
gene id: 32536:NRP2
uniprot id: A0A6I9ZRP2
uniprot id: A0A6I9ZV80
uniprot id: A0A6J1YTQ2
uniprot id: A0A6J1YX01
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:BANF2
gene id: 32536:BANF2
uniprot id: A0A6J2A662
names: Subcellular Location Annotation
messages: Nucleus

32536:EDEM2
gene id: 32536:EDEM2
uniprot id: A0A6I9ZT96
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

32536:LOC106979089
gene id: 32536:LOC106979089
uniprot id: A0A6I9ZWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

32536:CAMK2A
gene id: 32536:CAMK2A
uniprot id: A0A6J2ASD2
uniprot id: A0A6J2ASR4
uniprot id: A0A6J2AWR3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

32536:DAPK3
gene id: 32536:DAPK3
uniprot id: A0A6J1YLL1
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:VAPB
gene id: 32536:VAPB
uniprot id: A0A6J1YDB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:KIDINS220
gene id: 32536:KIDINS220
uniprot id: A0A6J2AU94
uniprot id: A0A6J2AU99
uniprot id: A0A6J2AUQ0
uniprot id: A0A6J2AUQ6
uniprot id: A0A6J2AWF8
uniprot id: A0A6J2AWG5
uniprot id: A0A6J2AYU9
uniprot id: A0A6J2AZL9
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

32536:CTC1
gene id: 32536:CTC1
uniprot id: A0A6J1YEN2
uniprot id: A0A6J1YFH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

32536:PALMD
gene id: 32536:PALMD
uniprot id: A0A6I9ZVS8
names: Similarity
messages: Belongs to the paralemmin family.

32536:STAM
gene id: 32536:STAM
uniprot id: A0A6J2AIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

32536:SERPINB7
gene id: 32536:SERPINB7
uniprot id: A0A6J0A3K0
names: Similarity
messages: Belongs to the serpin family.

32536:CPB2
gene id: 32536:CPB2
uniprot id: A0A6I9ZLQ9
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:BTD
gene id: 32536:BTD
uniprot id: A0A6I9ZJN1
uniprot id: A0A6I9ZL88
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

32536:DAND5
gene id: 32536:DAND5
uniprot id: A0A6J0A6M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

32536:TRAF2
gene id: 32536:TRAF2
uniprot id: A0A6J1YQ19
uniprot id: A0A6J1YQE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

32536:SPATA31F1
gene id: 32536:SPATA31F1
uniprot id: A0A6I9ZTK2
names: Similarity
messages: Belongs to the SPATA31 family.

32536:AHCYL1
gene id: 32536:AHCYL1
uniprot id: A0A6J1Z9H4
uniprot id: A0A6J1ZAC9
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

32536:ACVRL1
gene id: 32536:ACVRL1
uniprot id: A0A6J1XHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

32536:MARK3
gene id: 32536:MARK3
uniprot id: A0A6I9ZV65
uniprot id: A0A6J1ZY35
uniprot id: A0A6J1ZYI1
uniprot id: A0A6J1ZYI7
uniprot id: A0A6J1ZZ96
uniprot id: A0A6J1ZZA0
uniprot id: A0A6J2A139
uniprot id: A0A6J2A144
uniprot id: A0A6J2A282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

32536:RER1
gene id: 32536:RER1
uniprot id: A0A6J1ZIJ8
uniprot id: A0A6J1ZJP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

32536:MAP6D1
gene id: 32536:MAP6D1
uniprot id: A0A6J1ZID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

32536:UBE4A
gene id: 32536:UBE4A
uniprot id: A0A6I9ZG71
uniprot id: A0A6J1XIV9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

32536:CCNYL1
gene id: 32536:CCNYL1
uniprot id: A0A6J1YW04
uniprot id: A0A6J1YW20
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

32536:PCSK5
gene id: 32536:PCSK5
uniprot id: A0A6J1XW72
uniprot id: A0A6J1XWZ9
names: Similarity
messages: Belongs to the peptidase S8 family.

32536:GNPDA2
gene id: 32536:GNPDA2
uniprot id: A0A6J1Z527
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

32536:FBP2
gene id: 32536:FBP2
uniprot id: A0A6I9ZMJ1
names: Similarity
messages: Belongs to the FBPase class 1 family.

32536:MEMO1
gene id: 32536:MEMO1
uniprot id: A0A6J1X6N6
names: Similarity
messages: Belongs to the MEMO1 family.

32536:RELL2
gene id: 32536:RELL2
uniprot id: A0A6J1Y354
names: Similarity
messages: Belongs to the RELT family.

32536:PPT2
gene id: 32536:PPT2
uniprot id: A0A6J1Z9X5
uniprot id: A0A6J1ZC38
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

32536:PIK3C2A
gene id: 32536:PIK3C2A
uniprot id: A0A6I9ZXD8
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:RBBP5
gene id: 32536:RBBP5
uniprot id: A0A6I9ZPK5
uniprot id: A0A6I9ZQY6
names: Subcellular Location Annotation
messages: Nucleus

32536:HAAO
gene id: 32536:HAAO
uniprot id: A0A6I9ZWM9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

32536:TMEFF1
gene id: 32536:TMEFF1
uniprot id: A0A6J1XS45
uniprot id: A0A6J1XSE7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:UBE2B
gene id: 32536:UBE2B
uniprot id: A0A6J0AAZ3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:MPEG1
gene id: 32536:MPEG1
uniprot id: A0A6J0A8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPEG1 family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

32536:MPPE1
gene id: 32536:MPPE1
uniprot id: A0A6J2A369
uniprot id: A0A6J2A4B7
uniprot id: A0A6J2A6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Interacts with GPI-anchor proteins. Interacts with TMED10.
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

32536:SEPHS2
gene id: 32536:SEPHS2
uniprot id: A0A6I9ZYS1
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

32536:TYK2
gene id: 32536:TYK2
uniprot id: A0A6J1YML3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.

32536:TMEM225
gene id: 32536:TMEM225
uniprot id: A0A6I9ZWM0
names: Subcellular Location Annotation
messages: Membrane

32536:TRAPPC13
gene id: 32536:TRAPPC13
uniprot id: A0A6I9ZFY1
uniprot id: A0A6I9ZHA4
uniprot id: A0A6I9ZIR7
uniprot id: A0A6I9ZKP2
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

32536:ENGASE
gene id: 32536:ENGASE
uniprot id: A0A6J1YS73
uniprot id: A0A6J1YS74
uniprot id: A0A6J1YTN3
uniprot id: A0A6J1YVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

32536:MSTO1
gene id: 32536:MSTO1
uniprot id: A0A6J1YGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

32536:MAN1A2
gene id: 32536:MAN1A2
uniprot id: A0A6I9ZZH9
uniprot id: A0A6J1ZA11
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

32536:MAPK14
gene id: 32536:MAPK14
uniprot id: A0A6J1ZAA2
uniprot id: A0A6J1ZBM4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

32536:COQ3
gene id: 32536:COQ3
uniprot id: A0A6J1Z702
uniprot id: A0A6J1Z8C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

32536:PARP12
gene id: 32536:PARP12
uniprot id: A0A6J2AN29
names: Similarity
messages: Belongs to the ARTD/PARP family.

32536:SLC35A5
gene id: 32536:SLC35A5
uniprot id: A0A6I9ZKK6
uniprot id: A0A6I9ZM30
uniprot id: A0A6I9ZNR6
uniprot id: A0A6I9ZQ61
uniprot id: A0A6I9ZQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:NCOR2
gene id: 32536:NCOR2
uniprot id: A0A6J1Y748
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

32536:NOTO
gene id: 32536:NOTO
uniprot id: A0A6J2AHW1
names: Subcellular Location Annotation
messages: Nucleus

32536:CEP44
gene id: 32536:CEP44
uniprot id: A0A6J2A5B6
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

32536:GLRA1
gene id: 32536:GLRA1
uniprot id: A0A6I9ZH21
uniprot id: A0A6I9ZIQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite

32536:EXOC8
gene id: 32536:EXOC8
uniprot id: A0A6J1YEL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

32536:WDR82
gene id: 32536:WDR82
uniprot id: A0A6J1XQ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

32536:GAST
gene id: 32536:GAST
uniprot id: A0A6J1YJU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine.
messages: Secreted

32536:ABCB9
gene id: 32536:ABCB9
uniprot id: A0A6J1Y5R4
names: Subcellular Location Annotation
messages: Membrane

32536:SULF1
gene id: 32536:SULF1
uniprot id: A0A6J0A721
uniprot id: A0A6J1ZRT1
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

32536:DYNC2LI1
gene id: 32536:DYNC2LI1
uniprot id: A0A6J2AIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

32536:FAM83H
gene id: 32536:FAM83H
uniprot id: A0A6J1YUJ0
uniprot id: A0A6J1YUK0
names: Similarity
messages: Belongs to the FAM83 family.

32536:SHROOM3
gene id: 32536:SHROOM3
uniprot id: A0A6J1ZAG8
uniprot id: A0A6J1ZDV1
uniprot id: A0A6J1ZDV7
uniprot id: A0A6J1ZDX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

32536:CA2H19orf53
gene id: 32536:CA2H19orf53
uniprot id: A0A6J0A4H4
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.

32536:PRODH
gene id: 32536:PRODH
uniprot id: A0A6J0A1S0
uniprot id: A0A6J0A1X4
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

32536:HPGD
gene id: 32536:HPGD
uniprot id: A0A6J2A5E6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:ORAI2
gene id: 32536:ORAI2
uniprot id: A0A6J1Y000
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

32536:CFAP157
gene id: 32536:CFAP157
uniprot id: A0A6J1XES9
names: Similarity
messages: Belongs to the CFAP157 family.

32536:GRIA1
gene id: 32536:GRIA1
uniprot id: A0A6J2AVG9
uniprot id: A0A6J2AYN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:PPP4R2
gene id: 32536:PPP4R2
uniprot id: A0A6J1Y1C7
names: Similarity
messages: Belongs to the PPP4R2 family.

32536:LOC106970327
gene id: 32536:LOC106970327
uniprot id: A0A6J1YCB4
uniprot id: A0A6J1YCE8
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

32536:GPN2
gene id: 32536:GPN2
uniprot id: A0A6I9ZSW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

32536:TRPC3
gene id: 32536:TRPC3
uniprot id: A0A6J1ZQD4
names: Subcellular Location Annotation
messages: Membrane

32536:QRFP
gene id: 32536:QRFP
uniprot id: A0A6J0A7F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

32536:TUBGCP5
gene id: 32536:TUBGCP5
uniprot id: A0A6J0A5E7
uniprot id: A0A6J0A5I5
uniprot id: A0A6J0A5J1
uniprot id: A0A6J0A818
uniprot id: A0A6J0A8A9
uniprot id: A0A6J0A955
uniprot id: A0A6J2A1G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

32536:ATP4B
gene id: 32536:ATP4B
uniprot id: A0A6J0A5D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

32536:UBIAD1
gene id: 32536:UBIAD1
uniprot id: A0A6J0A5Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

32536:POPDC2
gene id: 32536:POPDC2
uniprot id: A0A6I9ZEW0
uniprot id: A0A6I9ZGD3
uniprot id: A0A6J1ZKB4
names: Similarity
messages: Belongs to the popeye family.

32536:ZNF706
gene id: 32536:ZNF706
uniprot id: A0A6I9ZWZ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:PLCB3
gene id: 32536:PLCB3
uniprot id: A0A6J1Y9J6
uniprot id: A0A6J1YA79
names: Cofactor
names: Function
messages: Binds 1 Ca(2+) ion per subunit.
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

32536:NDUFAF3
gene id: 32536:NDUFAF3
uniprot id: A0A6J1XPP1
uniprot id: A0A6J1XPY6
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

32536:MACF1
gene id: 32536:MACF1
uniprot id: A0A6J1ZD79
uniprot id: A0A6J1ZFB8
names: Subcellular Location Annotation
messages: cytoskeleton

32536:ARL5A
gene id: 32536:ARL5A
uniprot id: A0A6I9ZQT9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

32536:AURKAIP1
gene id: 32536:AURKAIP1
uniprot id: A0A6J1ZIP2
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mS38 family.

32536:CD70
gene id: 32536:CD70
uniprot id: A0A6J1YKW3
names: Similarity
messages: Belongs to the tumor necrosis factor family.

32536:HOXC10
gene id: 32536:HOXC10
uniprot id: A0A6J0A4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

32536:LOC106979940
gene id: 32536:LOC106979940
uniprot id: A0A6J2A8F9
uniprot id: E3VVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

32536:SRP72
gene id: 32536:SRP72
uniprot id: A0A6I9ZJQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

32536:RNH1
gene id: 32536:RNH1
uniprot id: A0A6J1YPT7
uniprot id: A0A6J1YPU2
uniprot id: A0A6J1YPU9
uniprot id: A0A6J1YR81
uniprot id: A0A6J1YRM7
uniprot id: A0A6J1YSX0
uniprot id: A0A6J1YSX5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

32536:F9
gene id: 32536:F9
uniprot id: A0A6I9ZLP0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:COPG1
gene id: 32536:COPG1
uniprot id: A0A6I9ZUF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

32536:DLL4
gene id: 32536:DLL4
uniprot id: A0A6J2A2Z6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

32536:SAP30L
gene id: 32536:SAP30L
uniprot id: A0A6J2AY65
names: Similarity
messages: Belongs to the SAP30 family.

32536:USP48
gene id: 32536:USP48
uniprot id: A0A6J1ZH31
uniprot id: A0A6J1ZI39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

32536:LITAF
gene id: 32536:LITAF
uniprot id: A0A6J0AAZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

32536:PTCH1
gene id: 32536:PTCH1
uniprot id: A0A6J1YG58
uniprot id: A0A6J1YGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

32536:LOC113597652
gene id: 32536:LOC113597652
uniprot id: A0A6J1Z087
names: Similarity
messages: Belongs to the TEX13 family.

32536:RAB3IP
gene id: 32536:RAB3IP
uniprot id: A0A6I9ZGI8
names: Similarity
messages: Belongs to the SEC2 family.

32536:IL7R
gene id: 32536:IL7R
uniprot id: A0A6I9ZYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
messages: The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

32536:PPTC7
gene id: 32536:PPTC7
uniprot id: A0A6I9ZFE1
names: Similarity
messages: Belongs to the PP2C family.

32536:UBE2G2
gene id: 32536:UBE2G2
uniprot id: A0A6J1XXB9
uniprot id: A0A6J1XXM1
uniprot id: A0A6J1XXP7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:ZFX
gene id: 32536:ZFX
uniprot id: A0A6J1YZ55
uniprot id: A0A6J1YZ59
uniprot id: A0A6J1Z159
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106989349
gene id: 32536:LOC106989349
uniprot id: A0A6J1XUK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:H1-6
gene id: 32536:H1-6
uniprot id: A0A6J0A9V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

32536:SERPING1
gene id: 32536:SERPING1
uniprot id: A0A6J1Y7J9
names: Similarity
messages: Belongs to the serpin family.

32536:MARS2
gene id: 32536:MARS2
uniprot id: A0A6J1YZ41
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:GTPBP8
gene id: 32536:GTPBP8
uniprot id: A0A6I9ZNS2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

32536:LOC106966627
gene id: 32536:LOC106966627
uniprot id: A0A6J1YTZ1
uniprot id: A0A6J1YTZ2
names: Similarity
messages: Belongs to the MHC class I family.

32536:PPARD
gene id: 32536:PPARD
uniprot id: A0A6J1ZAC3
uniprot id: A0A6J1ZBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:FDFT1
gene id: 32536:FDFT1
uniprot id: A0A6I9ZRT0
uniprot id: A0A6J2A9U1
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

32536:ELOVL7
gene id: 32536:ELOVL7
uniprot id: A0A6J1XX09
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

32536:DZIP3
gene id: 32536:DZIP3
uniprot id: A0A6I9ZKJ6
uniprot id: A0A6J2AYF4
names: Subcellular Location Annotation
messages: Cytoplasm

32536:GK5
gene id: 32536:GK5
uniprot id: A0A6J1ZK99
uniprot id: A0A6J1ZMP9
names: Similarity
messages: Belongs to the FGGY kinase family.

32536:ERFL
gene id: 32536:ERFL
uniprot id: A0A6J1XM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:CDC20
gene id: 32536:CDC20
uniprot id: A0A6I9ZM62
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

32536:LAMP1
gene id: 32536:LAMP1
uniprot id: A0A6J1ZWS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

32536:STS
gene id: 32536:STS
uniprot id: A0A6J1YPE9
names: Similarity
messages: Belongs to the sulfatase family.

32536:CXCR6
gene id: 32536:CXCR6
uniprot id: A0A6J1XPE0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:EIPR1
gene id: 32536:EIPR1
uniprot id: A0A6J2AUM2
uniprot id: A0A6J2AYR4
uniprot id: A0A6J2AZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EIPR1 family.
messages: trans-Golgi network

32536:GPR107
gene id: 32536:GPR107
uniprot id: A0A6J1XFD3
names: Subcellular Location Annotation
messages: Membrane

32536:BLOC1S2
gene id: 32536:BLOC1S2
uniprot id: A0A6I9ZFQ1
names: Similarity
messages: Belongs to the BLOC1S2 family.

32536:SEPHS1
gene id: 32536:SEPHS1
uniprot id: A0A6J2AIL5
uniprot id: A0A6J2AL29
uniprot id: A0A6J2ALF9
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

32536:PTH1R
gene id: 32536:PTH1R
uniprot id: A0A6J1XPA4
uniprot id: A0A6J1XPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

32536:PRR5
gene id: 32536:PRR5
uniprot id: A0A6J2A8V1
uniprot id: A0A6J2A8V4
uniprot id: A0A6J2AD56
names: Similarity
messages: Belongs to the PROTOR family.

32536:SPARC
gene id: 32536:SPARC
uniprot id: A0A6I9ZFI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: basement membrane

32536:LOC106986269
gene id: 32536:LOC106986269
uniprot id: A0A6J0A4R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RPS6KA1
gene id: 32536:RPS6KA1
uniprot id: A0A6I9ZUB3
uniprot id: A0A6J1ZFE7
uniprot id: A0A6J1ZGG6
uniprot id: A0A6J1ZHK1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

32536:ENTPD2
gene id: 32536:ENTPD2
uniprot id: A0A6J1YRU9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

32536:LOC106966280
gene id: 32536:LOC106966280
uniprot id: A0A6I9ZBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

32536:GRIN2A
gene id: 32536:GRIN2A
uniprot id: A0A6J1Y306
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

32536:METAP1
gene id: 32536:METAP1
uniprot id: A0A6J1ZJ16
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

32536:HDAC7
gene id: 32536:HDAC7
uniprot id: A0A6J1XH02
uniprot id: A0A6J1XH05
uniprot id: A0A6J1XH10
uniprot id: A0A6J1XH18
uniprot id: A0A6J1XH22
uniprot id: A0A6J1XH26
uniprot id: A0A6J1XH62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

32536:TMEM50A
gene id: 32536:TMEM50A
uniprot id: A0A6I9ZXT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

32536:GTF2B
gene id: 32536:GTF2B
uniprot id: A0A6I9ZG62
names: Similarity
messages: Belongs to the TFIIB family.

32536:IL15
gene id: 32536:IL15
uniprot id: A0A6I9ZW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

32536:CPLX2
gene id: 32536:CPLX2
uniprot id: A0A6J1XDV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

32536:SLC12A1
gene id: 32536:SLC12A1
uniprot id: A0A6I9ZEU9
uniprot id: A0A6I9ZI17
uniprot id: A0A6I9ZI30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

32536:SPATS2L
gene id: 32536:SPATS2L
uniprot id: A0A6I9ZWX9
names: Similarity
messages: Belongs to the SPATS2 family.

32536:TCTN2
gene id: 32536:TCTN2
uniprot id: A0A6J1Y544
uniprot id: A0A6J1Y5N7
uniprot id: A0A6J1Y6V7
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

32536:RPSA
gene id: 32536:RPSA
uniprot id: A0A6I9ZH43
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

32536:LIN7C
gene id: 32536:LIN7C
uniprot id: A0A6I9ZJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

32536:ACSF2
gene id: 32536:ACSF2
uniprot id: A0A6J1XBK2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:RPS29
gene id: 32536:RPS29
uniprot id: A0A6J0A3H0
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Component of the 40S small ribosomal subunit.

32536:TRIM32
gene id: 32536:TRIM32
uniprot id: A0A6J1XE50
names: Similarity
messages: Belongs to the TRIM/RBCC family.

32536:TMA16
gene id: 32536:TMA16
uniprot id: A0A6I9ZDP6
uniprot id: A0A6I9ZF57
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

32536:LOC106971928
gene id: 32536:LOC106971928
uniprot id: A0A6J2AP99
uniprot id: A0A6J2AR87
uniprot id: A0A6J2ATY2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

32536:PHOSPHO2
gene id: 32536:PHOSPHO2
uniprot id: A0A6J1Z3J5
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

32536:HSDL1
gene id: 32536:HSDL1
uniprot id: A0A6J2AU93
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:GDA
gene id: 32536:GDA
uniprot id: A0A6I9ZD38
uniprot id: A0A6I9ZG42
uniprot id: A0A6J1XW77
uniprot id: A0A6J1XW85
uniprot id: A0A6J1XWK6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

32536:CPEB1
gene id: 32536:CPEB1
uniprot id: A0A6I9ZEE1
uniprot id: A0A6J2A6H4
names: Similarity
messages: Belongs to the RRM CPEB family.

32536:PPP1R14B
gene id: 32536:PPP1R14B
uniprot id: A0A6J1Y7Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

32536:GJA5
gene id: 32536:GJA5
uniprot id: A0A6J0A4E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

32536:LOC106988221
gene id: 32536:LOC106988221
uniprot id: A0A6J2A1I8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RPL9
gene id: 32536:RPL9
uniprot id: A0A6J0A6F2
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

32536:ARPC1B
gene id: 32536:ARPC1B
uniprot id: A0A6J1XZN7
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

32536:NTHL1
gene id: 32536:NTHL1
uniprot id: A0A6J1Y319
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Interacts with YBX1.
messages: Mitochondrion
messages: Nucleus

32536:AKR1D1
gene id: 32536:AKR1D1
uniprot id: A0A6I9ZJI9
names: Similarity
messages: Belongs to the aldo/keto reductase family.

32536:ADORA2A
gene id: 32536:ADORA2A
uniprot id: A0A6I9ZXD9
uniprot id: A0A6J0A0H3
uniprot id: A0A6J1Y4R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

32536:ADCY5
gene id: 32536:ADCY5
uniprot id: A0A6J1ZIB8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Membrane

32536:ZNF532
gene id: 32536:ZNF532
uniprot id: A0A6J2A5Y9
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

32536:GDPD2
gene id: 32536:GDPD2
uniprot id: A0A6J1YW86
uniprot id: A0A6J1YXH5
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

32536:ATP6V0C
gene id: 32536:ATP6V0C
uniprot id: A0A6J1Y2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

32536:HOXB13
gene id: 32536:HOXB13
uniprot id: A0A6J1XAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

32536:TRAPPC2L
gene id: 32536:TRAPPC2L
uniprot id: A0A6J2AUN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

32536:TTI2
gene id: 32536:TTI2
uniprot id: A0A6I9ZDN0
names: Similarity
messages: Belongs to the TTI2 family.

32536:TMEM65
gene id: 32536:TMEM65
uniprot id: A0A6J1ZQQ5
uniprot id: A0A6J1ZT05
uniprot id: A0A6J1ZUF5
names: Subcellular Location Annotation
messages: Membrane

32536:EIF3L
gene id: 32536:EIF3L
uniprot id: A0A6J0A1J3
uniprot id: A0A6J2ADG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit L family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RRN3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

32536:TRPC4
gene id: 32536:TRPC4
uniprot id: A0A6J1ZV85
names: Subcellular Location Annotation
messages: Membrane

32536:SLC19A3
gene id: 32536:SLC19A3
uniprot id: A0A6I9ZNV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

32536:LOC106986496
gene id: 32536:LOC106986496
uniprot id: A0A6J0A4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PRR15L
gene id: 32536:PRR15L
uniprot id: A0A6I9ZXK2
names: Similarity
messages: Belongs to the PRR15 family.

32536:TUT4
gene id: 32536:TUT4
uniprot id: A0A6J1ZBQ4
uniprot id: A0A6J1ZE23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

32536:SLC25A3
gene id: 32536:SLC25A3
uniprot id: A0A6I9ZQM2
uniprot id: A0A6J2AEM3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

32536:LOC106969284
gene id: 32536:LOC106969284
uniprot id: A0A6J1XH66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

32536:CAPZB
gene id: 32536:CAPZB
uniprot id: A0A6J1ZEZ9
uniprot id: A0A6J1ZG57
uniprot id: A0A6J1ZHB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

32536:SEPTIN1
gene id: 32536:SEPTIN1
uniprot id: A0A6J1YRX8
uniprot id: A0A6J1YSD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

32536:LOC106965909
gene id: 32536:LOC106965909
uniprot id: A0A6I9ZCX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CHRNB1
gene id: 32536:CHRNB1
uniprot id: A0A6J1YF11
uniprot id: A0A6J1YFU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:B9D2
gene id: 32536:B9D2
uniprot id: A0A6J1XLK3
names: Subcellular Location Annotation
messages: cilium basal body

32536:IP6K1
gene id: 32536:IP6K1
uniprot id: A0A6J1XQ25
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

32536:ESYT2
gene id: 32536:ESYT2
uniprot id: A0A6J1YPC3
uniprot id: A0A6J1YPC4
uniprot id: A0A6J1YR52
uniprot id: A0A6J1YSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106986316
gene id: 32536:LOC106986316
uniprot id: A0A6J0A8H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ID2
gene id: 32536:ID2
uniprot id: A0A6J0A117
names: Subcellular Location Annotation
messages: Nucleus

32536:SERPINB2
gene id: 32536:SERPINB2
uniprot id: A0A6J0A692
names: Similarity
messages: Belongs to the serpin family.

32536:ADAM11
gene id: 32536:ADAM11
uniprot id: A0A6J1YHY2
uniprot id: A0A6J1YHZ6
uniprot id: A0A6J1YIU0
uniprot id: A0A6J1YJG1
uniprot id: A0A6J1YK85
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TMEM198
gene id: 32536:TMEM198
uniprot id: A0A6I9ZMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane

32536:ACTN2
gene id: 32536:ACTN2
uniprot id: A0A6J1YCK2
uniprot id: A0A6J1YCN1
names: Similarity
messages: Belongs to the alpha-actinin family.

32536:HSPB7
gene id: 32536:HSPB7
uniprot id: A0A6I9ZVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Nucleus

32536:ZFHX2
gene id: 32536:ZFHX2
uniprot id: A0A6J1ZUI0
uniprot id: A0A6J1ZUI6
names: Subcellular Location Annotation
messages: Nucleus

32536:STK17A
gene id: 32536:STK17A
uniprot id: A0A6J2AC40
uniprot id: A0A6J2AG79
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:LOC106986787
gene id: 32536:LOC106986787
uniprot id: A0A6J0A941
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:OCRL
gene id: 32536:OCRL
uniprot id: A0A6J1YXU0
uniprot id: A0A6J1YZV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

32536:CEP55
gene id: 32536:CEP55
uniprot id: A0A6I9ZBD7
uniprot id: A0A6J1ZQI2
names: Subcellular Location Annotation
messages: Cytoplasm

32536:CDC42EP4
gene id: 32536:CDC42EP4
uniprot id: A0A6J1YFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

32536:MEAF6
gene id: 32536:MEAF6
uniprot id: A0A6J1ZEF2
uniprot id: A0A6J1ZFE9
uniprot id: A0A6J1ZGJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

32536:PRKAA1
gene id: 32536:PRKAA1
uniprot id: A0A6I9ZKA1
uniprot id: A0A6J2AQJ3
uniprot id: A0A6J2ASS5
uniprot id: A0A6J2ASU1
uniprot id: A0A6J2AT85
uniprot id: A0A6J2ATA0
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

32536:AXL
gene id: 32536:AXL
uniprot id: A0A6J1XLR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

32536:ATG13
gene id: 32536:ATG13
uniprot id: A0A6I9ZTP0
uniprot id: A0A6I9ZXB1
uniprot id: A0A6I9ZY97
uniprot id: A0A6I9ZYF9
uniprot id: A0A6J2AF50
uniprot id: A0A6J2AFI4
uniprot id: A0A6J2AJI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

32536:DNMT3B
gene id: 32536:DNMT3B
uniprot id: A0A6J2ABA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

32536:P4HA3
gene id: 32536:P4HA3
uniprot id: A0A6J1XSU2
uniprot id: A0A6J1XT23
uniprot id: A0A6J1XT60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

32536:MKS1
gene id: 32536:MKS1
uniprot id: A0A6J0ABL9
uniprot id: A0A6J1XC08
names: Subcellular Location Annotation
messages: cilium basal body

32536:ISG15
gene id: 32536:ISG15
uniprot id: A0A6J0ABR3
names: Subcellular Location Annotation
messages: cytosol

32536:LOC106983476
gene id: 32536:LOC106983476
uniprot id: A0A6J1Z9Z1
uniprot id: A0A6J1ZAU9
names: Similarity
messages: Belongs to the cytochrome P450 family.

32536:IFT57
gene id: 32536:IFT57
uniprot id: A0A6J2AUB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

32536:LOC106976076
gene id: 32536:LOC106976076
uniprot id: A0A6J1Z962
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

32536:GDF3
gene id: 32536:GDF3
uniprot id: A0A6I9ZCA3
names: Similarity
messages: Belongs to the TGF-beta family.

32536:IL33
gene id: 32536:IL33
uniprot id: A0A6J0A6L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: Vesicle
messages: secretory vesicle

32536:BTG2
gene id: 32536:BTG2
uniprot id: A0A6J2AKK6
names: Similarity
messages: Belongs to the BTG family.

32536:ATPAF2
gene id: 32536:ATPAF2
uniprot id: A0A6J1YFD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

32536:NEU4
gene id: 32536:NEU4
uniprot id: A0A6J1Y7Y6
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

32536:TSEN15
gene id: 32536:TSEN15
uniprot id: A0A6J2ANN8
names: Similarity
messages: Belongs to the SEN15 family.

32536:RPIA
gene id: 32536:RPIA
uniprot id: A0A6I9ZV81
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

32536:TMEM145
gene id: 32536:TMEM145
uniprot id: A0A6J1XLT6
names: Subcellular Location Annotation
messages: Membrane

32536:GLUD1
gene id: 32536:GLUD1
uniprot id: A0A6J1ZMF9
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

32536:CAB39L
gene id: 32536:CAB39L
uniprot id: A0A6J1ZSS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

32536:GRAMD1A
gene id: 32536:GRAMD1A
uniprot id: A0A6J1Y775
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:PIGN
gene id: 32536:PIGN
uniprot id: A0A6I9ZZ92
uniprot id: A0A6J0A030
uniprot id: A0A6J2A510
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

32536:WNT4
gene id: 32536:WNT4
uniprot id: A0A6J1ZF23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

32536:MICOS13
gene id: 32536:MICOS13
uniprot id: A0A6I9ZRE3
uniprot id: A0A6I9ZV67
uniprot id: A0A6J1YLG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

32536:MTCP1
gene id: 32536:MTCP1
uniprot id: A0A6J0A2T2
names: Similarity
messages: Belongs to the TCL1 family.

32536:ZMYND10
gene id: 32536:ZMYND10
uniprot id: A0A6I9ZZU5
uniprot id: A0A6J1XQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

32536:LOC113598147
gene id: 32536:LOC113598147
uniprot id: A0A6J0AC98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MC4R
gene id: 32536:MC4R
uniprot id: A0A6J2A4Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

32536:TLR8
gene id: 32536:TLR8
uniprot id: A0A6J1YYK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

32536:SLC7A3
gene id: 32536:SLC7A3
uniprot id: A0A6J0A048
uniprot id: A0A6J0A328
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

32536:ARHGDIB
gene id: 32536:ARHGDIB
uniprot id: A0A6I9ZE11
names: Similarity
messages: Belongs to the Rho GDI family.

32536:STX7
gene id: 32536:STX7
uniprot id: A0A6I9ZWZ3
uniprot id: A0A6J1Z7A2
names: Similarity
messages: Belongs to the syntaxin family.

32536:RAP2A
gene id: 32536:RAP2A
uniprot id: A0A6J1ZTN8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

32536:CAPN6
gene id: 32536:CAPN6
uniprot id: A0A6J1Z0W2
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PGLYRP2
gene id: 32536:PGLYRP2
uniprot id: A0A6J1YLD5
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

32536:SELENOT
gene id: 32536:SELENOT
uniprot id: A0A6I9ZUT3
names: Similarity
messages: Belongs to the SelWTH family. Selenoprotein T subfamily.

32536:GRID1
gene id: 32536:GRID1
uniprot id: A0A6J1ZME2
uniprot id: A0A6J1ZQ12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:LRP2
gene id: 32536:LRP2
uniprot id: A0A6J1Z3K4
names: Caution
names: Similarity
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:EVA1C
gene id: 32536:EVA1C
uniprot id: A0A6J1XZ37
names: Similarity
messages: Belongs to the EVA1 family.

32536:ADRA1A
gene id: 32536:ADRA1A
uniprot id: A0A6I9ZF81
uniprot id: A0A6I9ZGX1
uniprot id: A0A6J2AT10
uniprot id: A0A6J2AV06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: caveola

32536:LOC113600255
gene id: 32536:LOC113600255
uniprot id: A0A6J1ZPR1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sodium-independent sulfate anion transporter. Can transport other anions including bicarbonate, thiosulfate and oxalate.

32536:TLR7
gene id: 32536:TLR7
uniprot id: A0A6I9ZKI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
messages: Lysosome
messages: Membrane
messages: phagosome

32536:CDIP1
gene id: 32536:CDIP1
uniprot id: A0A6I9ZUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane

32536:INSIG1
gene id: 32536:INSIG1
uniprot id: A0A6J1YQL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

32536:ALOX12B
gene id: 32536:ALOX12B
uniprot id: A0A6J1YEV2
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:FEV
gene id: 32536:FEV
uniprot id: A0A6J1Y7E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:INKA2
gene id: 32536:INKA2
uniprot id: A0A6J1ZBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

32536:TYW3
gene id: 32536:TYW3
uniprot id: A0A6I9ZLH3
uniprot id: A0A6I9ZQA2
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

32536:CAPN12
gene id: 32536:CAPN12
uniprot id: A0A6J1Y714
uniprot id: A0A6J1Y801
names: Similarity
messages: Belongs to the peptidase C2 family.

32536:HSD17B10
gene id: 32536:HSD17B10
uniprot id: A0A6J1YVS8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:AMBN
gene id: 32536:AMBN
uniprot id: A0A6J1ZSU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ameloblastin family.
messages: Involved in the mineralization and structural organization of enamel.
messages: extracellular matrix

32536:FUBP1
gene id: 32536:FUBP1
uniprot id: A0A6J1ZAQ2
uniprot id: A0A6J1ZBH5
uniprot id: A0A6J1ZCY0
uniprot id: A0A6J1ZCY9
uniprot id: A0A6J1ZE33
uniprot id: A0A6J1ZE38
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106969879
gene id: 32536:LOC106969879
uniprot id: A0A6I9ZJX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CD8A
gene id: 32536:CD8A
uniprot id: A0A6J1YTF1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:BMS1
gene id: 32536:BMS1
uniprot id: A0A6J1ZLM8
uniprot id: A0A6J1ZLZ2
names: Subcellular Location Annotation
messages: nucleolus

32536:ADD2
gene id: 32536:ADD2
uniprot id: A0A6J2AE19
uniprot id: A0A6J2AHN0
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

32536:USP45
gene id: 32536:USP45
uniprot id: A0A6J1Z6Z3
uniprot id: A0A6J1Z7K4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:DESI2
gene id: 32536:DESI2
uniprot id: A0A6J1YBN2
uniprot id: A0A6J1YC89
names: Similarity
messages: Belongs to the DeSI family.

32536:PTGER4
gene id: 32536:PTGER4
uniprot id: A0A6I9ZLP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

32536:MID1IP1
gene id: 32536:MID1IP1
uniprot id: A0A6J1Z0P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

32536:LOC106984987
gene id: 32536:LOC106984987
uniprot id: A0A6J1XL88
names: Subcellular Location Annotation
messages: Nucleus

32536:CREG2
gene id: 32536:CREG2
uniprot id: A0A6J2A5M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

32536:PTPRT
gene id: 32536:PTPRT
uniprot id: A0A6J2A7T9
uniprot id: A0A6J2A7U2
uniprot id: A0A6J2A7U7
uniprot id: A0A6J2A7X2
uniprot id: A0A6J2A8S0
uniprot id: A0A6J2A8S5
uniprot id: A0A6J2ABM3
uniprot id: A0A6J2ABN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

32536:TMC7
gene id: 32536:TMC7
uniprot id: A0A6J1Y215
uniprot id: A0A6J1Y2H1
uniprot id: A0A6J1Y2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

32536:SASS6
gene id: 32536:SASS6
uniprot id: A0A6I9ZSL4
uniprot id: A0A6J1ZC40
names: Subcellular Location Annotation
messages: centrosome

32536:RHBDF2
gene id: 32536:RHBDF2
uniprot id: A0A6J1YS40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

32536:TMEM121
gene id: 32536:TMEM121
uniprot id: A0A6J1ZZJ7
names: Similarity
messages: Belongs to the TMEM121 family.

32536:LPCAT4
gene id: 32536:LPCAT4
uniprot id: A0A6I9ZH51
uniprot id: A0A6J2A2P3
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

32536:DYNC1LI1
gene id: 32536:DYNC1LI1
uniprot id: A0A6J1XWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

32536:SLC25A19
gene id: 32536:SLC25A19
uniprot id: A0A6J0A6V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:SPATA31F3
gene id: 32536:SPATA31F3
uniprot id: A0A6J1XRS4
uniprot id: A0A6J1XRW7
names: Similarity
messages: Belongs to the SPATA31 family.

32536:RHPN1
gene id: 32536:RHPN1
uniprot id: A0A6J1ZQ40
uniprot id: A0A6J1ZQW5
uniprot id: A0A6J1ZSD7
uniprot id: A0A6J1ZTN7
names: Similarity
messages: Belongs to the RHPN family.

32536:PEG3
gene id: 32536:PEG3
uniprot id: A0A6J1XLA6
names: Subcellular Location Annotation
messages: Nucleus

32536:TMEM254
gene id: 32536:TMEM254
uniprot id: A0A6I9ZJN6
names: Subcellular Location Annotation
messages: Membrane

32536:SYCE1
gene id: 32536:SYCE1
uniprot id: A0A6J1ZPG5
uniprot id: A0A6J1ZQ68
names: Similarity
messages: Belongs to the SYCE family.

32536:DIO3
gene id: 32536:DIO3
uniprot id: A0A6J0A962
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

32536:IFRD1
gene id: 32536:IFRD1
uniprot id: A0A6J2ARB7
uniprot id: A0A6J2ARU4
names: Similarity
messages: Belongs to the IFRD family.

32536:BRF1
gene id: 32536:BRF1
uniprot id: A0A6J1ZYR6
names: Similarity
messages: Belongs to the TFIIB family.

32536:TTC4
gene id: 32536:TTC4
uniprot id: A0A6J1ZBI3
names: Similarity
messages: Belongs to the TTC4 family.

32536:PTGES3
gene id: 32536:PTGES3
uniprot id: A0A6J2ABQ4
uniprot id: A0A6J2AFV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

32536:F11R
gene id: 32536:F11R
uniprot id: A0A6J1YHF9
uniprot id: A0A6J1YI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: tight junction

32536:CCSER2
gene id: 32536:CCSER2
uniprot id: A0A6I9ZJK9
uniprot id: A0A6I9ZMK2
uniprot id: A0A6J1ZL88
uniprot id: A0A6J1ZLJ4
uniprot id: A0A6J1ZMD6
uniprot id: A0A6J1ZNP1
uniprot id: A0A6J1ZQ08
names: Similarity
messages: Belongs to the CCSER family.

32536:PABPN1
gene id: 32536:PABPN1
uniprot id: A0A6J0AA59
names: Similarity
messages: Belongs to the Bcl-2 family.

32536:CRLS1
gene id: 32536:CRLS1
uniprot id: A0A6I9ZWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

32536:BHMT
gene id: 32536:BHMT
uniprot id: A0A6I9ZNT9
uniprot id: A0A6I9ZSB3
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

32536:SCAMP4
gene id: 32536:SCAMP4
uniprot id: A0A6J1YLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

32536:RXRG
gene id: 32536:RXRG
uniprot id: A0A6I9ZAY2
uniprot id: A0A6I9ZCE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

32536:LZTS2
gene id: 32536:LZTS2
uniprot id: A0A6J1ZMG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTS2 family.
messages: Cytoplasm
messages: Interacts with KATNB1. Also interacts with CTNNB1, gamma-tubulin and KIF23.
messages: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
messages: centrosome

32536:CACNG2
gene id: 32536:CACNG2
uniprot id: A0A6J2ADN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

32536:PLPP2
gene id: 32536:PLPP2
uniprot id: A0A6J1YIX2
uniprot id: A0A6J1YKG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

32536:PLPP4
gene id: 32536:PLPP4
uniprot id: A0A6I9ZHY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

32536:VPS13A
gene id: 32536:VPS13A
uniprot id: A0A6J1XW52
uniprot id: A0A6J1XWH5
uniprot id: A0A6J1XWX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS13 family.
messages: Lipid droplet

32536:FAIM2
gene id: 32536:FAIM2
uniprot id: A0A6J1XHC9
uniprot id: A0A6J1XHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

32536:PPP2R5A
gene id: 32536:PPP2R5A
uniprot id: A0A6I9ZH80
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

32536:MCOLN2
gene id: 32536:MCOLN2
uniprot id: A0A6J1ZAG4
uniprot id: A0A6J1ZDW1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

32536:ADGRL1
gene id: 32536:ADGRL1
uniprot id: A0A6J1YMG5
uniprot id: A0A6J1YMX4
names: Subcellular Location Annotation
messages: Membrane

32536:STAT5B
gene id: 32536:STAT5B
uniprot id: A0A6J1YID6
uniprot id: A0A6J1YJ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

32536:SS18L2
gene id: 32536:SS18L2
uniprot id: A0A6J1XVK4
names: Similarity
messages: Belongs to the SS18 family.

32536:KAT2B
gene id: 32536:KAT2B
uniprot id: A0A6I9ZZ18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

32536:TIMP4
gene id: 32536:TIMP4
uniprot id: A0A6I9ZX03
names: Similarity
messages: Belongs to the protease inhibitor I35 (TIMP) family.

32536:SLC25A41
gene id: 32536:SLC25A41
uniprot id: A0A6I9ZV61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:SLC7A6
gene id: 32536:SLC7A6
uniprot id: A0A6I9ZK47
names: Subcellular Location Annotation
messages: Membrane

32536:ACTL6A
gene id: 32536:ACTL6A
uniprot id: A0A6J1ZIH7
uniprot id: A0A6J1ZLQ9
names: Similarity
messages: Belongs to the actin family.

32536:ARF3
gene id: 32536:ARF3
uniprot id: A0A6I9ZLA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

32536:LOC106970339
gene id: 32536:LOC106970339
uniprot id: A0A6I9ZMX2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:AP2B1
gene id: 32536:AP2B1
uniprot id: A0A6I9ZXG6
uniprot id: A0A6I9ZYC4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

32536:SLC25A30
gene id: 32536:SLC25A30
uniprot id: A0A6J1ZSZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:PPP4C
gene id: 32536:PPP4C
uniprot id: A0A6J1YTL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family.
messages: Cytoplasm

32536:TLX3
gene id: 32536:TLX3
uniprot id: A0A6J1XCF1
names: Subcellular Location Annotation
messages: Nucleus

32536:SMARCAD1
gene id: 32536:SMARCAD1
uniprot id: A0A6J1ZGP3
uniprot id: A0A6J1ZJ20
names: Subcellular Location Annotation
messages: Chromosome

32536:LOC106970266
gene id: 32536:LOC106970266
uniprot id: A0A6J2AK36
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

32536:IL24
gene id: 32536:IL24
uniprot id: A0A6I9ZZU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

32536:NMNAT2
gene id: 32536:NMNAT2
uniprot id: A0A6J2ANQ5
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

32536:RFT1
gene id: 32536:RFT1
uniprot id: A0A6J1XQF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

32536:LOC106988064
gene id: 32536:LOC106988064
uniprot id: A0A6J1XU59
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:PPP1R14A
gene id: 32536:PPP1R14A
uniprot id: A0A6J1Y830
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

32536:CETN1
gene id: 32536:CETN1
uniprot id: A0A6I9ZHA2
names: Similarity
messages: Belongs to the centrin family.

32536:TLN1
gene id: 32536:TLN1
uniprot id: A0A6J1XS12
names: Subcellular Location Annotation
messages: cytoskeleton

32536:TMEM199
gene id: 32536:TMEM199
uniprot id: A0A6J0A1D6
uniprot id: A0A6J1XCS5
uniprot id: A0A6J1XCT7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106974596
gene id: 32536:LOC106974596
uniprot id: A0A6I9ZU27
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GALNT4
gene id: 32536:GALNT4
uniprot id: A0A6I9ZV03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:CFTR
gene id: 32536:CFTR
uniprot id: A0A6I9ZJX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Membrane
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and NHERF1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through NHERF1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation.
messages: Recycling endosome membrane

32536:NR3C1
gene id: 32536:NR3C1
uniprot id: A0A6J1Y0A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

32536:CMTR1
gene id: 32536:CMTR1
uniprot id: A0A6I9ZL77
uniprot id: A0A6J1ZA51
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with POLR2A (via C-terminus).
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

32536:RPL6
gene id: 32536:RPL6
uniprot id: A0A6J0A038
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

32536:ACAA2
gene id: 32536:ACAA2
uniprot id: A0A6I9ZQN2
uniprot id: A0A6J2A8M9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

32536:LOC106988974
gene id: 32536:LOC106988974
uniprot id: A0A6J2AUX0
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Homotetramer.

32536:C1D
gene id: 32536:C1D
uniprot id: A0A6I9ZFK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

32536:TRAPPC11
gene id: 32536:TRAPPC11
uniprot id: A0A6J0A003
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

32536:ARL5B
gene id: 32536:ARL5B
uniprot id: A0A6J2AHT7
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

32536:LECT2
gene id: 32536:LECT2
uniprot id: A0A6J2AV96
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.

32536:PGR
gene id: 32536:PGR
uniprot id: A0A6J1XTJ4
uniprot id: A0A6J1XTU5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

32536:LOC106974716
gene id: 32536:LOC106974716
uniprot id: A0A6I9ZS90
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

32536:TRMT2A
gene id: 32536:TRMT2A
uniprot id: A0A6J0A4J5
uniprot id: A0A6J0A5L8
uniprot id: A0A6J1YMX5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PRL
gene id: 32536:PRL
uniprot id: A0A6J1XV34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

32536:HOXA4
gene id: 32536:HOXA4
uniprot id: A0A6J0A3X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:LOC106977781
gene id: 32536:LOC106977781
uniprot id: A0A6I9ZXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:STEAP1
gene id: 32536:STEAP1
uniprot id: A0A6J0A7Z0
uniprot id: A0A6J0AAG0
names: Subcellular Location Annotation
messages: Membrane

32536:SLC16A3
gene id: 32536:SLC16A3
uniprot id: A0A6J1YUG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

32536:HAX1
gene id: 32536:HAX1
uniprot id: A0A6J1YJ85
names: Function
names: Similarity
messages: Belongs to the HAX1 family.
messages: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

32536:PRKAB1
gene id: 32536:PRKAB1
uniprot id: A0A6J1Y5X6
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

32536:CD27
gene id: 32536:CD27
uniprot id: A0A6I9ZF96
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:GPR3
gene id: 32536:GPR3
uniprot id: A0A6J1ZGD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:PDGFA
gene id: 32536:PDGFA
uniprot id: A0A6J1Y0R6
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

32536:TM9SF3
gene id: 32536:TM9SF3
uniprot id: A0A6J1ZQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

32536:LOC106970184
gene id: 32536:LOC106970184
uniprot id: A0A6I9ZKE1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CD2H10orf90
gene id: 32536:CD2H10orf90
uniprot id: A0A6J1ZNT5
uniprot id: A0A6J1ZRC7
uniprot id: A0A6J1ZRD2
names: Subcellular Location Annotation
messages: centrosome

32536:PTP4A3
gene id: 32536:PTP4A3
uniprot id: A0A6J1ZPY5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

32536:DIPK1B
gene id: 32536:DIPK1B
uniprot id: A0A6J1YR36
uniprot id: A0A6J1YSI5
uniprot id: A0A6J1YSY2
names: Similarity
messages: Belongs to the DIPK family.

32536:LOC106977850
gene id: 32536:LOC106977850
uniprot id: A0A6I9ZY38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:EFNB3
gene id: 32536:EFNB3
uniprot id: A0A6J1YEG0
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC113598260
gene id: 32536:LOC113598260
uniprot id: A0A6J1Z4Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:VPS53
gene id: 32536:VPS53
uniprot id: A0A6I9ZVF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

32536:VMA21
gene id: 32536:VMA21
uniprot id: A0A6J1YVL4
uniprot id: A0A6J1YYW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

32536:GALNT14
gene id: 32536:GALNT14
uniprot id: A0A6J1X6L9
uniprot id: A0A6J1X6M4
uniprot id: A0A6J1X6M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:GAREM1
gene id: 32536:GAREM1
uniprot id: A0A6J2A401
uniprot id: A0A6J2A516
uniprot id: A0A6J2A7L6
names: Similarity
messages: Belongs to the GAREM family.

32536:NDUFS2
gene id: 32536:NDUFS2
uniprot id: A0A6J1YJK3
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

32536:TXNRD1
gene id: 32536:TXNRD1
uniprot id: A0A6J2AA04
uniprot id: A0A6J2ADZ4
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

32536:ATP13A1
gene id: 32536:ATP13A1
uniprot id: A0A6I9ZJ31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

32536:MRPL22
gene id: 32536:MRPL22
uniprot id: A0A6I9ZIM3
uniprot id: A0A6I9ZIQ3
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

32536:ABCC9
gene id: 32536:ABCC9
uniprot id: A0A6I9ZG11
uniprot id: A0A6I9ZHH7
uniprot id: A0A6J1XGC4
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with KCNJ11.
messages: Membrane

32536:DCLRE1B
gene id: 32536:DCLRE1B
uniprot id: A0A6I9ZLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

32536:SLC25A34
gene id: 32536:SLC25A34
uniprot id: A0A6J1ZGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:MTFMT
gene id: 32536:MTFMT
uniprot id: A0A6J2A1L7
names: Similarity
messages: Belongs to the Fmt family.

32536:CHD4
gene id: 32536:CHD4
uniprot id: A0A6J2AIV2
uniprot id: A0A6J2AIV6
uniprot id: A0A6J2AJF5
uniprot id: A0A6J2AKL4
uniprot id: A0A6J2AKL9
uniprot id: A0A6J2AN30
uniprot id: A0A6J2ANI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

32536:ATP6V0D2
gene id: 32536:ATP6V0D2
uniprot id: A0A6I9ZX32
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

32536:NBL1
gene id: 32536:NBL1
uniprot id: A0A6J1ZHA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

32536:SPP2
gene id: 32536:SPP2
uniprot id: A0A6J1YEG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

32536:KMT2C
gene id: 32536:KMT2C
uniprot id: A0A6J1YPE1
uniprot id: A0A6J1YQT1
names: Subcellular Location Annotation
messages: Nucleus

32536:CTTNBP2
gene id: 32536:CTTNBP2
uniprot id: A0A6J2AMD8
uniprot id: A0A6J2AMR2
uniprot id: A0A6J2ARE8
uniprot id: A0A6J2ARW9
uniprot id: A0A6J2ARX4
names: Subcellular Location Annotation
messages: cell cortex
messages: dendritic spine

32536:LOC106971279
gene id: 32536:LOC106971279
uniprot id: A0A6I9ZPC0
names: Similarity
messages: Belongs to the cornifelin family.

32536:CITED2
gene id: 32536:CITED2
uniprot id: A0A6J1Z4Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

32536:LOC106965732
gene id: 32536:LOC106965732
uniprot id: A0A6I9ZB87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:SUSD6
gene id: 32536:SUSD6
uniprot id: A0A6J1ZWK8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TAAR5
gene id: 32536:TAAR5
uniprot id: A0A6I9ZTD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

32536:DLL1
gene id: 32536:DLL1
uniprot id: A0A6J1Z5Z2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

32536:FRZB
gene id: 32536:FRZB
uniprot id: A0A6J0A7R7
names: Caution
names: Function
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

32536:TMPRSS11F
gene id: 32536:TMPRSS11F
uniprot id: A0A6J1Z7T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

32536:NUBP2
gene id: 32536:NUBP2
uniprot id: A0A6J1Y364
uniprot id: A0A6J1Y411
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Nucleus
messages: centrosome

32536:MGAT2
gene id: 32536:MGAT2
uniprot id: A0A6J1ZWF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

32536:CRYBA4
gene id: 32536:CRYBA4
uniprot id: A0A6J1YPP4
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:PPP2R5E
gene id: 32536:PPP2R5E
uniprot id: A0A6J1ZX07
uniprot id: A0A6J1ZZY1
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

32536:LOC106969857
gene id: 32536:LOC106969857
uniprot id: A0A6I9ZJV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GTF2I
gene id: 32536:GTF2I
uniprot id: A0A6J1XYM8
uniprot id: A0A6J1XYQ7
uniprot id: A0A6J1XYS8
uniprot id: A0A6J1XZ33
uniprot id: A0A6J1XZ39
uniprot id: A0A6J1XZN2
uniprot id: A0A6J1XZN9
names: Subcellular Location Annotation
messages: Nucleus

32536:SARS2
gene id: 32536:SARS2
uniprot id: A0A6J1Y6X5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

32536:MLH1
gene id: 32536:MLH1
uniprot id: A0A6J0A0G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

32536:PSMB2
gene id: 32536:PSMB2
uniprot id: A0A6I9ZSB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:ARHGEF2
gene id: 32536:ARHGEF2
uniprot id: A0A6J1YGC3
uniprot id: A0A6J1YIG4
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

32536:WNT6
gene id: 32536:WNT6
uniprot id: A0A6J1YQ26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

32536:SNAP23
gene id: 32536:SNAP23
uniprot id: A0A6I9ZF80
uniprot id: A0A6I9ZJT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

32536:TSPAN7
gene id: 32536:TSPAN7
uniprot id: A0A6J1YYW2
uniprot id: A0A6J1YZQ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PPFIA3
gene id: 32536:PPFIA3
uniprot id: A0A6J1XMV1
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

32536:PTPRS
gene id: 32536:PTPRS
uniprot id: A0A6J1YJ82
uniprot id: A0A6J1YLK3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

32536:RNF7
gene id: 32536:RNF7
uniprot id: A0A6J0A2M8
uniprot id: A0A6J1ZKA9
names: Similarity
messages: Belongs to the RING-box family.

32536:LOC106970150
gene id: 32536:LOC106970150
uniprot id: A0A6I9ZKD5
uniprot id: A0A6J1Z7W8
uniprot id: A0A6J1Z8N7
uniprot id: A0A6J1ZA12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Endoplasmic reticulum

32536:GCNT3
gene id: 32536:GCNT3
uniprot id: A0A6I9ZQP0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

32536:ITFG1
gene id: 32536:ITFG1
uniprot id: A0A6I9ZCX8
uniprot id: A0A6J1Y7K1
names: Similarity
messages: Belongs to the TIP family.

32536:IWS1
gene id: 32536:IWS1
uniprot id: A0A6I9ZC42
uniprot id: A0A6I9ZF24
uniprot id: A0A6I9ZGK9
uniprot id: A0A6I9ZGQ1
uniprot id: A0A6J1Z6E7
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106980448
gene id: 32536:LOC106980448
uniprot id: A0A6J0A1R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:LOC106966166
gene id: 32536:LOC106966166
uniprot id: A0A6I9ZD82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:GPR141
gene id: 32536:GPR141
uniprot id: A0A6I9ZGW1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:TMEM168
gene id: 32536:TMEM168
uniprot id: A0A6I9ZID4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane
messages: Nucleus membrane

32536:CDA
gene id: 32536:CDA
uniprot id: A0A6J1ZEY0
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

32536:ASL
gene id: 32536:ASL
uniprot id: A0A6J1XYI9
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

32536:TNFRSF11B
gene id: 32536:TNFRSF11B
uniprot id: A0A6I9ZRG0
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106979005
gene id: 32536:LOC106979005
uniprot id: A0A6I9ZWE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:KCNG3
gene id: 32536:KCNG3
uniprot id: A0A6J1XAE5
uniprot id: A0A6J1XAE9
names: Subcellular Location Annotation
messages: Membrane

32536:BLOC1S1
gene id: 32536:BLOC1S1
uniprot id: A0A6J0A9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space

32536:ATP6V1B1
gene id: 32536:ATP6V1B1
uniprot id: A0A6I9ZE46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

32536:SLC9A7
gene id: 32536:SLC9A7
uniprot id: A0A6J1YYF7
uniprot id: A0A6J1YZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Endosome membrane
messages: Recycling endosome membrane

32536:ZNF703
gene id: 32536:ZNF703
uniprot id: A0A6J2A9E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

32536:ITPK1
gene id: 32536:ITPK1
uniprot id: A0A6J1ZYN0
names: Similarity
messages: Belongs to the ITPK1 family.

32536:TRIM2
gene id: 32536:TRIM2
uniprot id: A0A6J2A0L0
uniprot id: A0A6J2A1M8
uniprot id: A0A6J2A1S5
uniprot id: A0A6J2A3M0
uniprot id: A0A6J2A3M5
uniprot id: A0A6J2A3P5
uniprot id: A0A6J2A4K0
names: Similarity
messages: Belongs to the TRIM/RBCC family.

32536:HOPX
gene id: 32536:HOPX
uniprot id: A0A6J1Z7T6
names: Subcellular Location Annotation
messages: Nucleus

32536:PADI6
gene id: 32536:PADI6
uniprot id: A0A6I9ZPZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

32536:FMR1
gene id: 32536:FMR1
uniprot id: A0A6J1YZK2
uniprot id: A0A6J1YZK6
uniprot id: A0A6J1YZK8
uniprot id: A0A6J1YZL1
uniprot id: A0A6J1YZL8
uniprot id: A0A6J1Z0Q2
uniprot id: A0A6J1Z0Q8
uniprot id: A0A6J1Z0R2
uniprot id: A0A6J1Z1J9
uniprot id: A0A6J1Z1K6
uniprot id: A0A6J1Z1L1
uniprot id: A0A6J1Z1L6
uniprot id: A0A6J1Z2X5
uniprot id: A0A6J1Z2Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Stress granule
messages: Synapse
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

32536:MRPS6
gene id: 32536:MRPS6
uniprot id: A0A6J1XYY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

32536:SLC35D2
gene id: 32536:SLC35D2
uniprot id: A0A6J1YG00
uniprot id: A0A6J1YG03
uniprot id: A0A6J1YHB5
names: Subcellular Location Annotation
messages: Membrane

32536:TMEM59L
gene id: 32536:TMEM59L
uniprot id: A0A6J1XP26
uniprot id: A0A6J1XP54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:SLC25A42
gene id: 32536:SLC25A42
uniprot id: A0A6J1XP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:LOC106966130
gene id: 32536:LOC106966130
uniprot id: A0A6I9ZEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PRKCI
gene id: 32536:PRKCI
uniprot id: A0A6J0ACZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

32536:KCNJ8
gene id: 32536:KCNJ8
uniprot id: A0A6I9ZJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

32536:ITPR3
gene id: 32536:ITPR3
uniprot id: A0A6J1Z8B8
uniprot id: A0A6J1Z9N1
uniprot id: A0A6J1ZAI4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

32536:S1PR2
gene id: 32536:S1PR2
uniprot id: A0A6J1YLI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:BST1
gene id: 32536:BST1
uniprot id: A0A6J1XTD7
uniprot id: A0A6J1XTI5
uniprot id: A0A6J1XTV2
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

32536:RPL10A
gene id: 32536:RPL10A
uniprot id: A0A6I9ZMU0
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

32536:LOC106979366
gene id: 32536:LOC106979366
uniprot id: A0A6I9ZZ79
uniprot id: A0A6J1XDH9
names: Similarity
messages: Belongs to the NipSnap family.

32536:LOC106969841
gene id: 32536:LOC106969841
uniprot id: A0A6J1ZX81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MEOX2
gene id: 32536:MEOX2
uniprot id: A0A6J2AHB6
names: Subcellular Location Annotation
messages: Nucleus

32536:KCND1
gene id: 32536:KCND1
uniprot id: A0A6J0A8A8
uniprot id: A0A6J1YZI5
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

32536:DPH5
gene id: 32536:DPH5
uniprot id: A0A6I9ZUR8
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

32536:PPIL6
gene id: 32536:PPIL6
uniprot id: A0A6J1Z9F4
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:CLRN3
gene id: 32536:CLRN3
uniprot id: A0A6J0A6J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

32536:FAM72A
gene id: 32536:FAM72A
uniprot id: A0A6I9ZLC5
uniprot id: A0A6J2AQS0
names: Similarity
messages: Belongs to the FAM72 family.

32536:ATXN7L3
gene id: 32536:ATXN7L3
uniprot id: A0A6J1YIG5
uniprot id: A0A6J1YIG8
uniprot id: A0A6J1YK02
uniprot id: A0A6J1YKS6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ENY2 and USP22.
messages: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of USP22 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

32536:STX1B
gene id: 32536:STX1B
uniprot id: A0A6J1YTQ8
names: Similarity
messages: Belongs to the syntaxin family.

32536:DLX1
gene id: 32536:DLX1
uniprot id: A0A6J1Z4W4
names: Subcellular Location Annotation
messages: Nucleus

32536:CPA6
gene id: 32536:CPA6
uniprot id: A0A6I9ZM40
uniprot id: A0A6J1Y0Y2
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:KCNH7
gene id: 32536:KCNH7
uniprot id: A0A6J1Z3T8
uniprot id: A0A6J1Z597
names: Subcellular Location Annotation
messages: Membrane

32536:DKK3
gene id: 32536:DKK3
uniprot id: A0A6J2AHQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

32536:HGS
gene id: 32536:HGS
uniprot id: A0A6J1YWC2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
messages: multivesicular body membrane

32536:LOC106974605
gene id: 32536:LOC106974605
uniprot id: A0A6I9ZS13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ALG6
gene id: 32536:ALG6
uniprot id: A0A6J0A251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:PIP
gene id: 32536:PIP
uniprot id: A0A6J0A502
names: Similarity
names: Subunit
messages: Belongs to the PIP family.
messages: Monomer. Interacts with AZGP1.

32536:LOC106969363
gene id: 32536:LOC106969363
uniprot id: A0A6I9ZLE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NSF
gene id: 32536:NSF
uniprot id: A0A6J1YT20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

32536:IVD
gene id: 32536:IVD
uniprot id: A0A6J1ZYS9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

32536:BCL7C
gene id: 32536:BCL7C
uniprot id: A0A6I9ZWJ1
names: Similarity
messages: Belongs to the BCL7 family.

32536:HHATL
gene id: 32536:HHATL
uniprot id: A0A6I9ZFF9
uniprot id: A0A6I9ZH59
names: Subcellular Location Annotation
messages: Membrane

32536:RAB32
gene id: 32536:RAB32
uniprot id: A0A6J1Z538
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

32536:SCARF2
gene id: 32536:SCARF2
uniprot id: A0A6J1YK10
uniprot id: A0A6J1YK20
uniprot id: A0A6J1YL39
uniprot id: A0A6J1YMM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SLC19A1
gene id: 32536:SLC19A1
uniprot id: A0A6J1XXA0
uniprot id: A0A6J1XXA5
uniprot id: A0A6J1XXJ1
uniprot id: A0A6J1XXK9
uniprot id: A0A6J1XY81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: Membrane
messages: Transporter that mediates the import of reduced folates.

32536:RIOK1
gene id: 32536:RIOK1
uniprot id: A0A6J0A7U6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

32536:MED10
gene id: 32536:MED10
uniprot id: A0A6J2AML3
uniprot id: A0A6J2AMZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:LOC106972846
gene id: 32536:LOC106972846
uniprot id: A0A6J1XYI6
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

32536:NKX6-2
gene id: 32536:NKX6-2
uniprot id: A0A6J1ZSW5
names: Subcellular Location Annotation
messages: Nucleus

32536:HOGA1
gene id: 32536:HOGA1
uniprot id: A0A6J1ZM30
uniprot id: A0A6J1ZMD8
uniprot id: A0A6J1ZN75
uniprot id: A0A6J1ZPK0
uniprot id: A0A6J1ZQT7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

32536:LOC106979184
gene id: 32536:LOC106979184
uniprot id: A0A6I9ZZU7
uniprot id: A0A6J2AMF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

32536:PAX5
gene id: 32536:PAX5
uniprot id: A0A6J0A2X3
uniprot id: A0A6J1XS46
names: Subcellular Location Annotation
messages: Nucleus

32536:EPB41
gene id: 32536:EPB41
uniprot id: A0A6J1ZE10
uniprot id: A0A6J1ZEC6
uniprot id: A0A6J1ZEC9
uniprot id: A0A6J1ZF47
uniprot id: A0A6J1ZG61
uniprot id: A0A6J1ZG66
uniprot id: A0A6J1ZH97
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex
messages: cytoskeleton

32536:DOCK7
gene id: 32536:DOCK7
uniprot id: A0A6J1ZB96
uniprot id: A0A6J1ZBA1
uniprot id: A0A6J1ZC17
uniprot id: A0A6J1ZCP2
uniprot id: A0A6J1ZDJ2
uniprot id: A0A6J1ZEP7
uniprot id: A0A6J1ZEQ2
names: Similarity
messages: Belongs to the DOCK family.

32536:CNN2
gene id: 32536:CNN2
uniprot id: A0A6J1YJN9
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

32536:PITX1
gene id: 32536:PITX1
uniprot id: A0A6J2AT08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

32536:SLC4A4
gene id: 32536:SLC4A4
uniprot id: A0A6J1Z8S6
uniprot id: A0A6J1Z8T6
uniprot id: A0A6J1Z9M4
uniprot id: A0A6J1ZAY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

32536:CAT
gene id: 32536:CAT
uniprot id: A0A6I9ZVJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

32536:FAM199X
gene id: 32536:FAM199X
uniprot id: A0A6J1YVG8
uniprot id: A0A6J1YYR2
names: Similarity
messages: Belongs to the FAM199 family.

32536:DLX2
gene id: 32536:DLX2
uniprot id: A0A6J1Z1P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

32536:IL10
gene id: 32536:IL10
uniprot id: A0A6J2APC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-10 family.
messages: Homodimer. Interacts with IL10RA and IL10RB.
messages: Immune regulatory cytokine.
messages: Secreted

32536:BLOC1S6
gene id: 32536:BLOC1S6
uniprot id: A0A6J1ZZV3
names: Function
names: Similarity
messages: Belongs to the BLOC1S6 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process.

32536:WDPCP
gene id: 32536:WDPCP
uniprot id: A0A6I9ZQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

32536:LOC106970076
gene id: 32536:LOC106970076
uniprot id: A0A6J1YRK2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:TMEM237
gene id: 32536:TMEM237
uniprot id: A0A6I9ZXK3
uniprot id: A0A6I9ZYI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

32536:NOS1
gene id: 32536:NOS1
uniprot id: A0A6J1Y4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: dendritic spine
messages: sarcolemma

32536:SMO
gene id: 32536:SMO
uniprot id: A0A6J2AMN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium

32536:FBN2
gene id: 32536:FBN2
uniprot id: A0A6J2AVP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:CA14
gene id: 32536:CA14
uniprot id: A0A6J1Z3M9
uniprot id: A0A6J1Z4Z1
uniprot id: A0A6J1Z5N5
uniprot id: A0A6J1Z709
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

32536:TRMT13
gene id: 32536:TRMT13
uniprot id: A0A6I9ZR96
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

32536:ERBB2
gene id: 32536:ERBB2
uniprot id: A0A6J1XB04
uniprot id: A0A6J1XB08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

32536:FXYD6
gene id: 32536:FXYD6
uniprot id: A0A6J1XIR6
uniprot id: A0A6J1XIZ0
names: Similarity
messages: Belongs to the FXYD family.

32536:PARP1
gene id: 32536:PARP1
uniprot id: A0A6J1YB93
uniprot id: A0A6J1YB96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARTD/PARP family.
messages: Chromosome
messages: Interacts (when auto-poly-ADP-ribosylated) with AIFM1.
messages: Nucleus
messages: Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair.
messages: This cleavage form irreversibly binds to DNA breaks and interferes with DNA repair, promoting DNA damage-induced apoptosis.

32536:SPTLC2
gene id: 32536:SPTLC2
uniprot id: A0A6J1ZWZ4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

32536:BORCS5
gene id: 32536:BORCS5
uniprot id: A0A6I9ZDY8
uniprot id: A0A6J1XFY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane

32536:ENTREP3
gene id: 32536:ENTREP3
uniprot id: A0A6J1YGN7
uniprot id: A0A6J1YGQ8
uniprot id: A0A6J1YIV6
names: Similarity
messages: Belongs to the ENTREP family.

32536:XRCC5
gene id: 32536:XRCC5
uniprot id: A0A6J1YR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus

32536:PHF20L1
gene id: 32536:PHF20L1
uniprot id: A0A6J1ZQ75
uniprot id: A0A6J1ZRC0
names: Subcellular Location Annotation
messages: Nucleus

32536:CNMD
gene id: 32536:CNMD
uniprot id: A0A6J1ZVU5
uniprot id: A0A6J1ZXA1
names: Similarity
messages: Belongs to the chondromodulin-1 family.

32536:ALG5
gene id: 32536:ALG5
uniprot id: A0A6J1ZSI7
uniprot id: A0A6J1ZSW7
uniprot id: A0A6J1ZWJ9
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

32536:PDE7A
gene id: 32536:PDE7A
uniprot id: A0A6J0A445
uniprot id: A0A6J1Y1M2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:PAIP2
gene id: 32536:PAIP2
uniprot id: A0A6I9ZFW4
names: Similarity
messages: Belongs to the PAIP2 family.

32536:KCNA6
gene id: 32536:KCNA6
uniprot id: A0A6J2AJB9
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106969984
gene id: 32536:LOC106969984
uniprot id: A0A6I9ZM61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:MIPEP
gene id: 32536:MIPEP
uniprot id: A0A6J0AAT8
uniprot id: A0A6J0ABW7
uniprot id: A0A6J1ZW46
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

32536:MAGOH
gene id: 32536:MAGOH
uniprot id: A0A6I9ZP92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

32536:PTH2R
gene id: 32536:PTH2R
uniprot id: A0A6J1YV30
uniprot id: A0A6J1YV39
names: Subcellular Location Annotation
messages: Membrane

32536:LBH
gene id: 32536:LBH
uniprot id: A0A6I9ZJ24
uniprot id: A0A6J1X6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: Transcriptional activator.

32536:NPEPPS
gene id: 32536:NPEPPS
uniprot id: A0A6J1XB75
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

32536:KCNH1
gene id: 32536:KCNH1
uniprot id: A0A6J2AJV9
uniprot id: A0A6J2ALM7
uniprot id: A0A6J2AP34
names: Subcellular Location Annotation
messages: Membrane

32536:TMEM107
gene id: 32536:TMEM107
uniprot id: A0A6I9ZMD9
names: Subcellular Location Annotation
messages: Membrane

32536:GTF2A2
gene id: 32536:GTF2A2
uniprot id: A0A6J2A171
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

32536:CNTN2
gene id: 32536:CNTN2
uniprot id: A0A6J2AMN5
uniprot id: A0A6J2AQJ2
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

32536:SMUG1
gene id: 32536:SMUG1
uniprot id: A0A6J1XHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

32536:CRAT
gene id: 32536:CRAT
uniprot id: A0A6J1XF94
uniprot id: A0A6J1XF97
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

32536:PPM1E
gene id: 32536:PPM1E
uniprot id: A0A6J1XC47
names: Similarity
messages: Belongs to the PP2C family.

32536:GPX7
gene id: 32536:GPX7
uniprot id: A0A6J1ZCH6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

32536:LOC106985708
gene id: 32536:LOC106985708
uniprot id: A0A6J0A431
names: Similarity
messages: Belongs to the SSX family.

32536:DNAJA2
gene id: 32536:DNAJA2
uniprot id: A0A6J1Y638
names: Subcellular Location Annotation
messages: Membrane

32536:SHFL
gene id: 32536:SHFL
uniprot id: A0A6J1YQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHFL family.
messages: Cytoplasm
messages: Nucleus

32536:CAMSAP2
gene id: 32536:CAMSAP2
uniprot id: A0A6I9ZN53
uniprot id: A0A6I9ZPS2
uniprot id: A0A6I9ZRK7
uniprot id: A0A6I9ZRL1
uniprot id: A0A6I9ZSU6
uniprot id: A0A6I9ZSV1
uniprot id: A0A6I9ZTM1
uniprot id: A0A6J2APY0
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

32536:GINS3
gene id: 32536:GINS3
uniprot id: A0A6I9ZS50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

32536:HSD17B13
gene id: 32536:HSD17B13
uniprot id: A0A6I9ZJU2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:LPL
gene id: 32536:LPL
uniprot id: A0A6I9ZJY8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

32536:ZDHHC23
gene id: 32536:ZDHHC23
uniprot id: A0A6J1ZGR3
uniprot id: A0A6J1ZHY1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:OTP
gene id: 32536:OTP
uniprot id: A0A6J1XS95
names: Subcellular Location Annotation
messages: Nucleus

32536:CDC42SE1
gene id: 32536:CDC42SE1
uniprot id: A0A6J1Z6W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

32536:LIMS2
gene id: 32536:LIMS2
uniprot id: A0A6J1Z3C5
uniprot id: A0A6J1Z528
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

32536:PHF20
gene id: 32536:PHF20
uniprot id: A0A6J2AB70
names: Subcellular Location Annotation
messages: Nucleus

32536:CLUL1
gene id: 32536:CLUL1
uniprot id: A0A6J2A4S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

32536:USE1
gene id: 32536:USE1
uniprot id: A0A6J1XNN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:ANXA3
gene id: 32536:ANXA3
uniprot id: A0A6J1ZB63
uniprot id: A0A6J1ZB72
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

32536:FAM110A
gene id: 32536:FAM110A
uniprot id: A0A6J2A7M4
names: Similarity
messages: Belongs to the FAM110 family.

32536:TOP2B
gene id: 32536:TOP2B
uniprot id: A0A6J1XVX5
uniprot id: A0A6J1XWQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

32536:DTX4
gene id: 32536:DTX4
uniprot id: A0A6J1YB15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

32536:CRYZ
gene id: 32536:CRYZ
uniprot id: A0A6I9ZN18
uniprot id: A0A6I9ZPI3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

32536:MRPL17
gene id: 32536:MRPL17
uniprot id: A0A6J0A2M6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

32536:GPD2
gene id: 32536:GPD2
uniprot id: A0A6I9ZYM2
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

32536:SPR
gene id: 32536:SPR
uniprot id: A0A6I9ZIV1
names: Similarity
messages: Belongs to the sepiapterin reductase family.

32536:PPP1R11
gene id: 32536:PPP1R11
uniprot id: A0A6J1YSY7
names: Subunit
messages: Interacts with TLR2 and UBE2D2.

32536:TGFBI
gene id: 32536:TGFBI
uniprot id: A0A6J2AQY1
names: Subcellular Location Annotation
messages: extracellular matrix

32536:MED4
gene id: 32536:MED4
uniprot id: A0A6I9ZK62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:CCR8
gene id: 32536:CCR8
uniprot id: A0A6I9ZCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

32536:PSMC1
gene id: 32536:PSMC1
uniprot id: A0A6J0AB60
names: Similarity
messages: Belongs to the AAA ATPase family.

32536:LOC113598146
gene id: 32536:LOC113598146
uniprot id: A0A6J1Z2B1
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

32536:HSPB1
gene id: 32536:HSPB1
uniprot id: A0A6J1XZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus
messages: spindle

32536:IL21
gene id: 32536:IL21
uniprot id: A0A6I9ZXA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

32536:CTSK
gene id: 32536:CTSK
uniprot id: A0A6I9ZWS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

32536:NATD1
gene id: 32536:NATD1
uniprot id: A0A6J0A337
names: Similarity
messages: Belongs to the NATD1 family.

32536:SEC11A
gene id: 32536:SEC11A
uniprot id: A0A6J2A3G1
uniprot id: A0A6J2A6F6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106977807
gene id: 32536:LOC106977807
uniprot id: A0A6I9ZT67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MIS18A
gene id: 32536:MIS18A
uniprot id: A0A6I9ZDL4
uniprot id: A0A6J1XY60
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

32536:LOC106986186
gene id: 32536:LOC106986186
uniprot id: A0A6J0A763
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GKAP1
gene id: 32536:GKAP1
uniprot id: A0A6J1YHA1
names: Similarity
messages: Belongs to the GKAP1 family.

32536:ALDH2
gene id: 32536:ALDH2
uniprot id: A0A6J1Y3X2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:MAP3K5
gene id: 32536:MAP3K5
uniprot id: A0A6J1Z720
uniprot id: A0A6J1Z8F0
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

32536:KEAP1
gene id: 32536:KEAP1
uniprot id: A0A6J1YMM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KEAP1 family.
messages: Cytoplasm
messages: Nucleus

32536:GAS8
gene id: 32536:GAS8
uniprot id: A0A6J2AR12
uniprot id: A0A6J2AR16
uniprot id: A0A6J2ASJ6
uniprot id: A0A6J2AUW4
uniprot id: A0A6J2AVH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum
messages: flagellum axoneme

32536:PSAT1
gene id: 32536:PSAT1
uniprot id: A0A6J1XW41
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

32536:PPFIA4
gene id: 32536:PPFIA4
uniprot id: A0A6J2AKH7
uniprot id: A0A6J2AL51
uniprot id: A0A6J2AMB4
uniprot id: A0A6J2APP4
uniprot id: A0A6J2AQ71
uniprot id: A0A6J2AQ76
names: Similarity
messages: Belongs to the liprin family. Liprin-alpha subfamily.

32536:HSP90AA1
gene id: 32536:HSP90AA1
uniprot id: A0A6J2A227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

32536:TMEM216
gene id: 32536:TMEM216
uniprot id: A0A6I9ZWV7
uniprot id: A0A6J1Y9J3
names: Subcellular Location Annotation
messages: Membrane

32536:RIMKLA
gene id: 32536:RIMKLA
uniprot id: A0A6I9ZMJ2
uniprot id: A0A6J1ZE02
names: Similarity
messages: Belongs to the RimK family.

32536:ZPBP2
gene id: 32536:ZPBP2
uniprot id: A0A6J1XAY5
uniprot id: A0A6J1XAZ6
uniprot id: A0A6J1XAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: acrosome

32536:LOC106971058
gene id: 32536:LOC106971058
uniprot id: A0A6J1YZW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

32536:GPR161
gene id: 32536:GPR161
uniprot id: A0A6J1YB27
uniprot id: A0A6J1YC98
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:SLC30A7
gene id: 32536:SLC30A7
uniprot id: A0A6I9ZRA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

32536:LOC106981995
gene id: 32536:LOC106981995
uniprot id: A0A6J0A014
names: Subcellular Location Annotation
messages: Secreted

32536:CATSPERE
gene id: 32536:CATSPERE
uniprot id: A0A6J1YAS3
names: Similarity
messages: Belongs to the CATSPERD family.

32536:PON2
gene id: 32536:PON2
uniprot id: A0A6J2AD37
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

32536:GEM
gene id: 32536:GEM
uniprot id: A0A6I9ZTN6
uniprot id: A0A6J1ZR70
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

32536:TMEM45A
gene id: 32536:TMEM45A
uniprot id: A0A6J2AYB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

32536:TMEM17
gene id: 32536:TMEM17
uniprot id: A0A6J2AED0
names: Subcellular Location Annotation
messages: Membrane

32536:PDE6B
gene id: 32536:PDE6B
uniprot id: A0A6J1ZJK0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:DOCK11
gene id: 32536:DOCK11
uniprot id: A0A6J1YY35
uniprot id: A0A6J1YY53
uniprot id: A0A6J1YZB7
uniprot id: A0A6J1Z1E5
names: Similarity
messages: Belongs to the DOCK family.

32536:SHBG
gene id: 32536:SHBG
uniprot id: A0A6I9ZP12
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DGCR2
gene id: 32536:DGCR2
uniprot id: A0A6J1YK34
uniprot id: A0A6J1YL56
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:VGLL2
gene id: 32536:VGLL2
uniprot id: A0A6J1Z6B5
uniprot id: A0A6J1Z717
uniprot id: A0A6J1Z938
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

32536:KCNA5
gene id: 32536:KCNA5
uniprot id: A0A6I9ZF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

32536:CD36
gene id: 32536:CD36
uniprot id: A0A6J0A3Q9
names: Similarity
messages: Belongs to the CD36 family.

32536:BEGAIN
gene id: 32536:BEGAIN
uniprot id: A0A6J1ZYB2
uniprot id: A0A6J1ZZ29
uniprot id: A0A6J1ZZ33
uniprot id: A0A6J2A0X3
uniprot id: A0A6J2A212
names: Subcellular Location Annotation
messages: Membrane

32536:STAG1
gene id: 32536:STAG1
uniprot id: A0A6J1ZJA1
uniprot id: A0A6J1ZJM1
uniprot id: A0A6J1ZKH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

32536:ART3
gene id: 32536:ART3
uniprot id: A0A6J1ZB45
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

32536:AFF2
gene id: 32536:AFF2
uniprot id: A0A6J1YZG4
uniprot id: A0A6J1YZG7
uniprot id: A0A6J1YZG8
uniprot id: A0A6J1YZH3
uniprot id: A0A6J1Z0L5
uniprot id: A0A6J1Z0M1
uniprot id: A0A6J1Z1G4
uniprot id: A0A6J1Z1G9
uniprot id: A0A6J1Z2U1
uniprot id: A0A6J1Z2U5
names: Similarity
messages: Belongs to the AF4 family.

32536:ATP8B1
gene id: 32536:ATP8B1
uniprot id: A0A6J2A5W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

32536:TUBG1
gene id: 32536:TUBG1
uniprot id: A0A6J1YJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

32536:ABCA6
gene id: 32536:ABCA6
uniprot id: A0A6I9ZR77
uniprot id: A0A6I9ZT73
names: Subcellular Location Annotation
messages: Membrane

32536:HNRNPA3
gene id: 32536:HNRNPA3
uniprot id: A0A6J1Z1J6
uniprot id: A0A6J1Z2I5
uniprot id: A0A6J1Z381
uniprot id: A0A6J1Z4Q3
names: Subcellular Location Annotation
messages: Nucleus

32536:S100A9
gene id: 32536:S100A9
uniprot id: A0A6J0A8N9
names: Similarity
messages: Belongs to the S-100 family.

32536:GPRC5A
gene id: 32536:GPRC5A
uniprot id: A0A6J1XFZ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:PSAP
gene id: 32536:PSAP
uniprot id: A0A6I9ZI15
names: Subcellular Location Annotation
messages: Secreted

32536:SH3BGRL
gene id: 32536:SH3BGRL
uniprot id: A0A6J0A182
uniprot id: A0A6J1YWK0
uniprot id: A0A6J1YZT6
names: Similarity
messages: Belongs to the SH3BGR family.

32536:PRPF3
gene id: 32536:PRPF3
uniprot id: A0A6J0A7U2
uniprot id: A0A6J1Z704
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

32536:PLLP
gene id: 32536:PLLP
uniprot id: A0A6J2ANQ8
names: Subcellular Location Annotation
messages: Membrane

32536:GTF2A1L
gene id: 32536:GTF2A1L
uniprot id: A0A6J2AFT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

32536:PIK3CD
gene id: 32536:PIK3CD
uniprot id: A0A6J1ZGV1
uniprot id: A0A6J1ZI09
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:SLC5A6
gene id: 32536:SLC5A6
uniprot id: A0A6I9ZIZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

32536:LOC106976628
gene id: 32536:LOC106976628
uniprot id: A0A6I9ZWL5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GDF9
gene id: 32536:GDF9
uniprot id: A0A6I9ZK06
uniprot id: A0A6I9ZLF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

32536:PPOX
gene id: 32536:PPOX
uniprot id: A0A6J1YGN0
uniprot id: A0A6J1YGQ3
uniprot id: A0A6J1YHH2
uniprot id: A0A6J1YHH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

32536:LOC106976636
gene id: 32536:LOC106976636
uniprot id: A0A6I9ZT19
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GLIS3
gene id: 32536:GLIS3
uniprot id: A0A6J1XWV8
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

32536:SLC16A13
gene id: 32536:SLC16A13
uniprot id: A0A6J1YFJ3
names: Subcellular Location Annotation
messages: Membrane

32536:GNB4
gene id: 32536:GNB4
uniprot id: A0A6J1ZLR4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

32536:KATNAL2
gene id: 32536:KATNAL2
uniprot id: A0A6I9ZR06
uniprot id: A0A6I9ZRY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

32536:LOC106969818
gene id: 32536:LOC106969818
uniprot id: A0A6I9ZLH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106967658
gene id: 32536:LOC106967658
uniprot id: A0A6I9ZIP2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

32536:ISM1
gene id: 32536:ISM1
uniprot id: A0A6J2A664
uniprot id: A0A6J2A6A6
names: Similarity
messages: Belongs to the isthmin family.

32536:CWF19L1
gene id: 32536:CWF19L1
uniprot id: A0A6J1ZMC3
uniprot id: A0A6J1ZML5
names: Similarity
messages: Belongs to the CWF19 family.

32536:CANX
gene id: 32536:CANX
uniprot id: A0A6J2ATS5
names: Similarity
messages: Belongs to the calreticulin family.

32536:RAP1GDS1
gene id: 32536:RAP1GDS1
uniprot id: A0A6I9ZEY8
uniprot id: A0A6I9ZI61
uniprot id: A0A6I9ZI71
uniprot id: A0A6I9ZI76
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion

32536:POLR3B
gene id: 32536:POLR3B
uniprot id: A0A6I9ZK27
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

32536:HMBS
gene id: 32536:HMBS
uniprot id: A0A6J0A4U4
names: Similarity
messages: Belongs to the HMBS family.

32536:GGT5
gene id: 32536:GGT5
uniprot id: A0A6I9ZWB9
uniprot id: A0A6J1Y584
uniprot id: A0A6J1Y5F6
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

32536:FAM163B
gene id: 32536:FAM163B
uniprot id: A0A6J1YSI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

32536:PUS7L
gene id: 32536:PUS7L
uniprot id: A0A6I9ZYQ2
uniprot id: A0A6J1XGW8
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

32536:MXRA8
gene id: 32536:MXRA8
uniprot id: A0A6J1ZGP0
uniprot id: A0A6J1ZJU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:AGPAT4
gene id: 32536:AGPAT4
uniprot id: A0A6J0A6E5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

32536:FH
gene id: 32536:FH
uniprot id: A0A6J1YAF9
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

32536:SVOP
gene id: 32536:SVOP
uniprot id: A0A6I9ZYH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

32536:LAMTOR1
gene id: 32536:LAMTOR1
uniprot id: A0A6I9ZNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

32536:LMF1
gene id: 32536:LMF1
uniprot id: A0A6J1Y3B0
uniprot id: A0A6J1Y3J5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:NMT2
gene id: 32536:NMT2
uniprot id: A0A6J2AH72
uniprot id: A0A6J2AHL4
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

32536:MRAP2
gene id: 32536:MRAP2
uniprot id: A0A6J1Z8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:AASDH
gene id: 32536:AASDH
uniprot id: A0A6I9ZQ42
uniprot id: A0A6J1Z9N7
uniprot id: A0A6J1Z9N9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:LOC106980760
gene id: 32536:LOC106980760
uniprot id: A0A6I9ZXX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LYPLA1
gene id: 32536:LYPLA1
uniprot id: A0A6I9ZRC0
uniprot id: A0A6J1Y1I1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

32536:USP51
gene id: 32536:USP51
uniprot id: A0A6J0AAN3
uniprot id: A0A6J1YXS4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:WDR24
gene id: 32536:WDR24
uniprot id: A0A6J1Y429
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR24 family.
messages: Lysosome membrane

32536:SLC26A8
gene id: 32536:SLC26A8
uniprot id: A0A6J1ZBN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

32536:KDR
gene id: 32536:KDR
uniprot id: A0A6J1Z6Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

32536:EMP3
gene id: 32536:EMP3
uniprot id: A0A6J1XMM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probably involved in cell proliferation and cell-cell interactions.

32536:TNFRSF25
gene id: 32536:TNFRSF25
uniprot id: A0A6J1ZH41
uniprot id: A0A6J1ZIA1
uniprot id: A0A6J1ZJC8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CHMP2B
gene id: 32536:CHMP2B
uniprot id: A0A6I9ZL32
names: Similarity
messages: Belongs to the SNF7 family.

32536:TTC27
gene id: 32536:TTC27
uniprot id: A0A6I9ZHF3
names: Similarity
messages: Belongs to the TTC27 family.

32536:VPS18
gene id: 32536:VPS18
uniprot id: A0A6I9ZI73
uniprot id: A0A6J2A1W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

32536:F8
gene id: 32536:F8
uniprot id: A0A6J1YY64
names: Similarity
messages: Belongs to the multicopper oxidase family.

32536:LOC113593365
gene id: 32536:LOC113593365
uniprot id: A0A6J1XLB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MBOAT7
gene id: 32536:MBOAT7
uniprot id: A0A6J1XKZ2
uniprot id: A0A6J1XL11
names: Subcellular Location Annotation
messages: Membrane

32536:FTMT
gene id: 32536:FTMT
uniprot id: A0A6I9ZUA9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

32536:PANK4
gene id: 32536:PANK4
uniprot id: A0A6J1ZG69
names: Similarity
names: Subunit
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

32536:SLC10A1
gene id: 32536:SLC10A1
uniprot id: A0A6I9ZQ22
uniprot id: A0A6I9ZTX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

32536:MYO1F
gene id: 32536:MYO1F
uniprot id: A0A6J1YM01
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

32536:GATA5
gene id: 32536:GATA5
uniprot id: A0A6J1YDX1
names: Subcellular Location Annotation
messages: Nucleus

32536:ADGRL4
gene id: 32536:ADGRL4
uniprot id: A0A6I9ZGW9
uniprot id: A0A6J1ZCX1
uniprot id: A0A6J1ZE26
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PPP1R14D
gene id: 32536:PPP1R14D
uniprot id: A0A6J2A2Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

32536:OPLAH
gene id: 32536:OPLAH
uniprot id: A0A6J1ZS48
names: Similarity
messages: Belongs to the oxoprolinase family.

32536:TAGLN3
gene id: 32536:TAGLN3
uniprot id: A0A6I9ZNR2
names: Similarity
messages: Belongs to the calponin family.

32536:IFI44L
gene id: 32536:IFI44L
uniprot id: A0A6I9ZLV1
names: Similarity
messages: Belongs to the IFI44 family.

32536:RPS27L
gene id: 32536:RPS27L
uniprot id: A0A6J2A0C3
uniprot id: A0A6J2A0M6
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

32536:EZR
gene id: 32536:EZR
uniprot id: A0A6J1Z4D2
uniprot id: A0A6J1Z5S0
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

32536:XPNPEP2
gene id: 32536:XPNPEP2
uniprot id: A0A6J1YZ69
names: Similarity
messages: Belongs to the peptidase M24B family.

32536:ACTRT2
gene id: 32536:ACTRT2
uniprot id: A0A6J0A5L6
names: Similarity
messages: Belongs to the actin family.

32536:RPL3
gene id: 32536:RPL3
uniprot id: A0A6J2ADA2
uniprot id: A0A6J2ADN4
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

32536:WDR83OS
gene id: 32536:WDR83OS
uniprot id: A0A6J1YMD0
names: Similarity
messages: Belongs to the Asterix family.

32536:DUSP5
gene id: 32536:DUSP5
uniprot id: A0A6J1ZRN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

32536:TMED10
gene id: 32536:TMED10
uniprot id: A0A6J1ZZI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:RSPO4
gene id: 32536:RSPO4
uniprot id: A0A6J2A7L9
names: Similarity
messages: Belongs to the R-spondin family.

32536:TENT5D
gene id: 32536:TENT5D
uniprot id: A0A6J0A8S6
names: Similarity
messages: Belongs to the TENT family.

32536:KCNB2
gene id: 32536:KCNB2
uniprot id: A0A6I9ZJT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: dendrite

32536:HPRT1
gene id: 32536:HPRT1
uniprot id: A0A6J1YXW6
uniprot id: A0A6J1YXX9
uniprot id: A0A6J1YZ43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

32536:SIK3
gene id: 32536:SIK3
uniprot id: A0A6J1XIP0
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:LOC106966667
gene id: 32536:LOC106966667
uniprot id: A0A6I9ZH17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MOGS
gene id: 32536:MOGS
uniprot id: A0A6J0A826
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

32536:ALK
gene id: 32536:ALK
uniprot id: A0A6J1X6L5
uniprot id: A0A6J1XA23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane

32536:PLBD2
gene id: 32536:PLBD2
uniprot id: A0A6J1Y641
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

32536:CFAP126
gene id: 32536:CFAP126
uniprot id: A0A6I9ZUJ3
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

32536:SSH2
gene id: 32536:SSH2
uniprot id: A0A6I9ZGW6
uniprot id: A0A6J1XD25
uniprot id: A0A6J1XD48
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

32536:LOC106989865
gene id: 32536:LOC106989865
uniprot id: A0A6J0ABM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SMG1
gene id: 32536:SMG1
uniprot id: A0A6J1Y2I1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

32536:CCL17
gene id: 32536:CCL17
uniprot id: A0A6I9ZVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:BMPR2
gene id: 32536:BMPR2
uniprot id: A0A6I9ZYP2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

32536:NSMCE2
gene id: 32536:NSMCE2
uniprot id: A0A6J1ZQN5
uniprot id: A0A6J1ZUC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

32536:NDUFS8
gene id: 32536:NDUFS8
uniprot id: A0A6J1Y8T3
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

32536:GALNT13
gene id: 32536:GALNT13
uniprot id: A0A6J1Z237
uniprot id: A0A6J1Z2E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:CFAP91
gene id: 32536:CFAP91
uniprot id: A0A6I9ZJH8
uniprot id: A0A6J1ZGV7
uniprot id: A0A6J1ZI29
uniprot id: A0A6J1ZJ92
names: Similarity
messages: Belongs to the CFAP91 family.

32536:LOC106966152
gene id: 32536:LOC106966152
uniprot id: A0A6J1YUR9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

32536:SCUBE1
gene id: 32536:SCUBE1
uniprot id: A0A6J2A926
uniprot id: A0A6J2AA09
uniprot id: A0A6J2ACT8
uniprot id: A0A6J2AD84
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:LOC113597925
gene id: 32536:LOC113597925
uniprot id: A0A6J1Z0I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:INO80
gene id: 32536:INO80
uniprot id: A0A6J1ZYX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

32536:PHACTR3
gene id: 32536:PHACTR3
uniprot id: A0A6J1YBC2
uniprot id: A0A6J1YBC5
uniprot id: A0A6J1YBC8
uniprot id: A0A6J1YC00
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

32536:RPL26L1
gene id: 32536:RPL26L1
uniprot id: A0A6I9ZUG8
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

32536:CCKBR
gene id: 32536:CCKBR
uniprot id: A0A6J0A1Q3
uniprot id: A0A6J0A2M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:GPAT4
gene id: 32536:GPAT4
uniprot id: A0A6I9ZVI1
uniprot id: A0A6J2ABZ8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

32536:SERPINB11
gene id: 32536:SERPINB11
uniprot id: A0A6J0A7C8
names: Similarity
messages: Belongs to the serpin family.

32536:SMAD3
gene id: 32536:SMAD3
uniprot id: A0A6J0A1C0
uniprot id: A0A6J2A3S5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

32536:GPR89A
gene id: 32536:GPR89A
uniprot id: A0A6J0A7B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

32536:LPCAT1
gene id: 32536:LPCAT1
uniprot id: A0A6J2AJC0
uniprot id: A0A6J2ALS5
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

32536:EIF4G1
gene id: 32536:EIF4G1
uniprot id: A0A6J1ZHV9
uniprot id: A0A6J1ZI79
uniprot id: A0A6J1ZJ50
uniprot id: A0A6J1ZKA6
uniprot id: A0A6J1ZLG0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

32536:LOC106989622
gene id: 32536:LOC106989622
uniprot id: A0A6J1YZF3
names: Subcellular Location Annotation
messages: Nucleus

32536:VDAC1
gene id: 32536:VDAC1
uniprot id: A0A6J2AT46
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

32536:EIF3K
gene id: 32536:EIF3K
uniprot id: A0A6J0A0L4
uniprot id: A0A6J1Y621
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus

32536:CLDN2
gene id: 32536:CLDN2
uniprot id: A0A6J0A7L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

32536:SEPTIN7
gene id: 32536:SEPTIN7
uniprot id: A0A6J2AM62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium axoneme
messages: flagellum
messages: kinetochore
messages: spindle

32536:LOC106977816
gene id: 32536:LOC106977816
uniprot id: A0A6I9ZY18
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TM9SF2
gene id: 32536:TM9SF2
uniprot id: A0A6J1ZXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

32536:STAT4
gene id: 32536:STAT4
uniprot id: A0A6J1YYL6
uniprot id: A0A6J1Z0L0
uniprot id: A0A6J1Z0M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

32536:MTM1
gene id: 32536:MTM1
uniprot id: A0A6J1YVS1
uniprot id: A0A6J1YXK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

32536:DDIT4
gene id: 32536:DDIT4
uniprot id: A0A6J1ZKX7
names: Similarity
messages: Belongs to the DDIT4 family.

32536:LOC106976119
gene id: 32536:LOC106976119
uniprot id: A0A6I9ZVX3
names: Similarity
messages: Belongs to the MHC class II family.

32536:MAGT1
gene id: 32536:MAGT1
uniprot id: A0A6J0A716
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:POU1F1
gene id: 32536:POU1F1
uniprot id: A0A6I9ZGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

32536:ZER1
gene id: 32536:ZER1
uniprot id: A0A6J1XF74
uniprot id: A0A6J1XF85
names: Similarity
messages: Belongs to the zyg-11 family.

32536:SSBP2
gene id: 32536:SSBP2
uniprot id: A0A6J1XQH5
uniprot id: A0A6J1XQR3
uniprot id: A0A6J1XQV8
uniprot id: A0A6J1XQW8
names: Subcellular Location Annotation
messages: Nucleus

32536:SCAMP1
gene id: 32536:SCAMP1
uniprot id: A0A6J1XRU6
uniprot id: A0A6J1XS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

32536:TFCP2L1
gene id: 32536:TFCP2L1
uniprot id: A0A6J1Z2W1
uniprot id: A0A6J1Z466
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

32536:MPL
gene id: 32536:MPL
uniprot id: A0A6J1ZEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane

32536:DTD2
gene id: 32536:DTD2
uniprot id: A0A6I9ZUK6
names: Similarity
messages: Belongs to the DTD family.

32536:ETV5
gene id: 32536:ETV5
uniprot id: A0A6J1ZJ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:MAPT
gene id: 32536:MAPT
uniprot id: A0A6J1YRM0
uniprot id: A0A6J1YRM4
uniprot id: A0A6J1YRM5
uniprot id: A0A6J1YRM8
uniprot id: A0A6J1YRN1
uniprot id: A0A6J1YRN8
uniprot id: A0A6J1YT25
uniprot id: A0A6J1YT30
uniprot id: A0A6J1YT37
uniprot id: A0A6J1YTG7
uniprot id: A0A6J1YTH2
uniprot id: A0A6J1YTH7
uniprot id: A0A6J1YUT4
uniprot id: A0A6J1YUU0
uniprot id: A0A6J1YUU6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: axon
messages: cytoskeleton
messages: cytosol
messages: dendrite

32536:TMEM43
gene id: 32536:TMEM43
uniprot id: A0A6J1Y196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

32536:PFKFB4
gene id: 32536:PFKFB4
uniprot id: A0A6I9ZZU9
uniprot id: A0A6J1XPT6
uniprot id: A0A6J1XPT8
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

32536:TMEM178A
gene id: 32536:TMEM178A
uniprot id: A0A6J1XAA8
names: Similarity
messages: Belongs to the TMEM178 family.

32536:SUFU
gene id: 32536:SUFU
uniprot id: A0A6J1ZMM8
uniprot id: A0A6J1ZMX3
uniprot id: A0A6J1ZNS4
uniprot id: A0A6J1ZRE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutral state. Without the Hh signal, the SUFU-GLI3 complex is recruited to cilia, leading to the efficient processing of GLI3FL into GLI3R. When Hh signaling is initiated, SUFU dissociates from GLI3FL and the latter translocates to the nucleus, where it is phosphorylated, destabilized, and converted to a transcriptional activator (GLI3A).
messages: Nucleus

32536:LOC106973183
gene id: 32536:LOC106973183
uniprot id: A0A6J1ZDH0
uniprot id: A0A6J1ZDU6
uniprot id: A0A6J1ZEK9
uniprot id: A0A6J1ZFK7
uniprot id: A0A6J1ZGP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family.
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

32536:OVCA2
gene id: 32536:OVCA2
uniprot id: A0A6J1XDA4
names: Similarity
messages: Belongs to the LovG family.

32536:OASL
gene id: 32536:OASL
uniprot id: A0A6J1Y620
names: Similarity
messages: Belongs to the 2-5A synthase family.

32536:OLFML2A
gene id: 32536:OLFML2A
uniprot id: A0A6J1XEJ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:AHR
gene id: 32536:AHR
uniprot id: A0A6J2AEC4
names: Subcellular Location Annotation
messages: Cytoplasm

32536:PRKCA
gene id: 32536:PRKCA
uniprot id: A0A6J1YFP4
uniprot id: A0A6J1YH08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

32536:TPT1
gene id: 32536:TPT1
uniprot id: A0A6J1ZVL0
names: Similarity
messages: Belongs to the TCTP family.

32536:S1PR5
gene id: 32536:S1PR5
uniprot id: A0A6J1YME5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:CMTM3
gene id: 32536:CMTM3
uniprot id: A0A6J1Z118
uniprot id: A0A6J1Z460
names: Subcellular Location Annotation
messages: Membrane

32536:TASOR
gene id: 32536:TASOR
uniprot id: A0A6J1XQL0
uniprot id: A0A6J1XQL5
uniprot id: A0A6J1XQM4
uniprot id: A0A6J1XQT3
uniprot id: A0A6J1XQT7
uniprot id: A0A6J1XQU3
uniprot id: A0A6J1XQY4
uniprot id: A0A6J1XQY9
names: Similarity
messages: Belongs to the TASOR family.

32536:HAO2
gene id: 32536:HAO2
uniprot id: A0A6J1ZBD4
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

32536:PNLIP
gene id: 32536:PNLIP
uniprot id: A0A6I9ZPM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

32536:SMPX
gene id: 32536:SMPX
uniprot id: A0A6J0A0V2
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

32536:NAPRT
gene id: 32536:NAPRT
uniprot id: A0A6J1ZQ29
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

32536:LOC106980444
gene id: 32536:LOC106980444
uniprot id: A0A6J1XCF9
names: Similarity
messages: Belongs to the Schlafen family. Subgroup III subfamily.

32536:ACOT13
gene id: 32536:ACOT13
uniprot id: A0A6I9ZI08
names: Similarity
messages: Belongs to the thioesterase PaaI family.

32536:MARCO
gene id: 32536:MARCO
uniprot id: A0A6I9ZF33
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:LRRC42
gene id: 32536:LRRC42
uniprot id: A0A6J1ZF07
names: Similarity
messages: Belongs to the LRRC42 family.

32536:ACTRT1
gene id: 32536:ACTRT1
uniprot id: A0A6I9ZY25
names: Similarity
messages: Belongs to the actin family.

32536:CLTRN
gene id: 32536:CLTRN
uniprot id: A0A6I9ZN37
uniprot id: A0A6J1Z218
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:DHRS3
gene id: 32536:DHRS3
uniprot id: A0A6J0A7E6
uniprot id: A0A6J0AA22
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:AGAP2
gene id: 32536:AGAP2
uniprot id: A0A6J2AB94
uniprot id: A0A6J2ABI5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

32536:B4GALT6
gene id: 32536:B4GALT6
uniprot id: A0A6J0A202
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

32536:ERP29
gene id: 32536:ERP29
uniprot id: A0A6J1Y3Y2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Does not seem to be a disulfide isomerase.
messages: Endoplasmic reticulum lumen
messages: Homodimer.
messages: Melanosome

32536:LOC106970932
gene id: 32536:LOC106970932
uniprot id: A0A6I9ZLQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

32536:C3AR1
gene id: 32536:C3AR1
uniprot id: A0A6I9ZC03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

32536:ST8SIA6
gene id: 32536:ST8SIA6
uniprot id: A0A6J2ALQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:CASP8
gene id: 32536:CASP8
uniprot id: A0A6J1YW13
names: Similarity
messages: Belongs to the peptidase C14A family.

32536:ENOPH1
gene id: 32536:ENOPH1
uniprot id: A0A6I9ZPC5
uniprot id: A0A6J1ZFX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

32536:ATP2C2
gene id: 32536:ATP2C2
uniprot id: A0A6J2AQI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:EEF1G
gene id: 32536:EEF1G
uniprot id: A0A6J0A2X9
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

32536:MON2
gene id: 32536:MON2
uniprot id: A0A6I9ZYU7
uniprot id: A0A6J0A2Y2
names: Similarity
messages: Belongs to the MON2 family.

32536:GPX6
gene id: 32536:GPX6
uniprot id: A0A6J0A8U5
names: Similarity
messages: Belongs to the glutathione peroxidase family.

32536:LOC106987352
gene id: 32536:LOC106987352
uniprot id: A0A6J0A6E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106988213
gene id: 32536:LOC106988213
uniprot id: A0A6J0AA55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DOCK1
gene id: 32536:DOCK1
uniprot id: A0A6J1ZNU5
uniprot id: A0A6J1ZP58
uniprot id: A0A6J1ZPV8
names: Similarity
messages: Belongs to the DOCK family.

32536:USP26
gene id: 32536:USP26
uniprot id: A0A6J1YZD7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:PAN2
gene id: 32536:PAN2
uniprot id: A0A6J0A854
uniprot id: A0A6J2ABS0
uniprot id: A0A6J2ACQ4
uniprot id: A0A6J2AFF2
uniprot id: A0A6J2AFX0
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

32536:CDADC1
gene id: 32536:CDADC1
uniprot id: A0A6I9ZQJ1
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

32536:TCEA2
gene id: 32536:TCEA2
uniprot id: A0A6J1YDN0
uniprot id: A0A6J1YEC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

32536:LOXL2
gene id: 32536:LOXL2
uniprot id: A0A6J2AY96
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

32536:BDNF
gene id: 32536:BDNF
uniprot id: A0A6J2AG34
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NGF-beta family.
messages: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
messages: Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
messages: Monomers and homodimers (By similarity). Binds to NTRK2/TRKB. Can form heterodimers with other neurotrophin family members, such as NTF3 and NTF4 (in vitro), but the physiological relevance of this is not clear (By similarity). BDNF precursor form: interacts with the heterodimer formed by NGFR and SORCS2. Mature BDNF has much lower affinity for the heterodimer formed by NGFR and SORCS2.
messages: Monomers and homodimers. Binds to NTRK2/TRKB.
messages: Secreted

32536:PAMR1
gene id: 32536:PAMR1
uniprot id: A0A6I9ZTG9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DTWD2
gene id: 32536:DTWD2
uniprot id: A0A6J2ATI9
names: Similarity
messages: Belongs to the TDD superfamily. DTWD2 family.

32536:AURKC
gene id: 32536:AURKC
uniprot id: A0A6J0A6U6
uniprot id: A0A6J1XLB0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

32536:LAMP5
gene id: 32536:LAMP5
uniprot id: A0A6I9ZSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane
messages: Membrane

32536:BRAF
gene id: 32536:BRAF
uniprot id: A0A6J2AN55
uniprot id: A0A6J2ANJ7
uniprot id: A0A6J2AQ28
uniprot id: A0A6J2ASQ7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

32536:UTP14A
gene id: 32536:UTP14A
uniprot id: A0A6I9ZZN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP14 family.
messages: nucleolus

32536:ORMDL3
gene id: 32536:ORMDL3
uniprot id: A0A6J1XAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

32536:GGT1
gene id: 32536:GGT1
uniprot id: A0A6J1Y6F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

32536:UBE2K
gene id: 32536:UBE2K
uniprot id: A0A6J1Z228
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:NDUFA10
gene id: 32536:NDUFA10
uniprot id: A0A6J1YAY6
uniprot id: A0A6J1YC78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

32536:HKDC1
gene id: 32536:HKDC1
uniprot id: A0A6I9ZI00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

32536:PTS
gene id: 32536:PTS
uniprot id: A0A6J1XIJ5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the PTPS family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

32536:HMMR
gene id: 32536:HMMR
uniprot id: A0A6I9ZHV8
uniprot id: A0A6J1XAT4
names: Subcellular Location Annotation
messages: spindle

32536:PRPH2
gene id: 32536:PRPH2
uniprot id: A0A6I9ZRB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRPH2/ROM1 family.
messages: Membrane

32536:POLR2I
gene id: 32536:POLR2I
uniprot id: A0A6I9ZS84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

32536:HCN1
gene id: 32536:HCN1
uniprot id: A0A6J2AQR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

32536:BUD23
gene id: 32536:BUD23
uniprot id: A0A6I9ZU92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

32536:GPR142
gene id: 32536:GPR142
uniprot id: A0A6J1YFZ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:CSTF1
gene id: 32536:CSTF1
uniprot id: A0A6I9ZJD4
names: Subcellular Location Annotation
messages: Nucleus

32536:MARVELD3
gene id: 32536:MARVELD3
uniprot id: A0A6J0A9F1
uniprot id: A0A6J0AAE3
names: Subcellular Location Annotation
messages: Membrane

32536:RPS6KA2
gene id: 32536:RPS6KA2
uniprot id: A0A6J1Z464
uniprot id: A0A6J1Z4G4
uniprot id: A0A6J1Z649
uniprot id: A0A6J1Z7J7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

32536:LOC106986547
gene id: 32536:LOC106986547
uniprot id: A0A6J1Y530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

32536:LOC106979019
gene id: 32536:LOC106979019
uniprot id: A0A6I9ZV79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:HPSE
gene id: 32536:HPSE
uniprot id: A0A6J1ZE52
uniprot id: A0A6J1ZEW3
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

32536:ACAP3
gene id: 32536:ACAP3
uniprot id: A0A6J1ZGQ2
uniprot id: A0A6J1ZIR5
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

32536:PCSK7
gene id: 32536:PCSK7
uniprot id: A0A6J1XIY6
names: Similarity
messages: Belongs to the peptidase S8 family.

32536:LOC106978624
gene id: 32536:LOC106978624
uniprot id: A0A6I9ZUP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106987351
gene id: 32536:LOC106987351
uniprot id: A0A6J0A6A6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CD63
gene id: 32536:CD63
uniprot id: A0A6J2AG26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Cell surface
messages: Endosome membrane
messages: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome
messages: Membrane
messages: extracellular exosome
messages: multivesicular body

32536:TIMM13
gene id: 32536:TIMM13
uniprot id: A0A6J1YJB8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

32536:GPR17
gene id: 32536:GPR17
uniprot id: A0A6I9ZF18
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:PSMB6
gene id: 32536:PSMB6
uniprot id: A0A6I9ZP00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:KRI1
gene id: 32536:KRI1
uniprot id: A0A6J1YMD3
uniprot id: A0A6J1YNQ4
uniprot id: A0A6J1YP11
names: Similarity
messages: Belongs to the KRI1 family.

32536:LOC106985755
gene id: 32536:LOC106985755
uniprot id: A0A6J1Y1U1
uniprot id: A0A6J1Y255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

32536:PHETA2
gene id: 32536:PHETA2
uniprot id: A0A6J2ADF1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

32536:CASQ2
gene id: 32536:CASQ2
uniprot id: A0A6I9ZL83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

32536:DCTN2
gene id: 32536:DCTN2
uniprot id: A0A6I9ZV16
names: Similarity
messages: Belongs to the dynactin subunit 2 family.

32536:DGAT1
gene id: 32536:DGAT1
uniprot id: A0A6J1ZPH5
uniprot id: A0A6J1ZQK8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane

32536:SLC26A10P
gene id: 32536:SLC26A10P
uniprot id: A0A6J2AB98
uniprot id: A0A6J2ABI9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:DNAAF1
gene id: 32536:DNAAF1
uniprot id: A0A6J0A6Z4
uniprot id: A0A6J2AQ21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: Cilium-specific protein required for the stability of the ciliary architecture. Plays a role in cytoplasmic preassembly of dynein arms. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
messages: cilium

32536:PIGL
gene id: 32536:PIGL
uniprot id: A0A6I9ZYZ6
uniprot id: A0A6I9ZZJ4
uniprot id: A0A6J0A2P6
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

32536:NIPAL2
gene id: 32536:NIPAL2
uniprot id: A0A6J1ZS45
uniprot id: A0A6J1ZTM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

32536:MOV10
gene id: 32536:MOV10
uniprot id: A0A6J1ZBK8
uniprot id: A0A6J1ZCS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

32536:TRMT6
gene id: 32536:TRMT6
uniprot id: A0A6J2A6A9
uniprot id: A0A6J2A6E9
uniprot id: A0A6J2AA54
uniprot id: A0A6J2AAK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

32536:LRRC7
gene id: 32536:LRRC7
uniprot id: A0A6J1ZEB4
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

32536:FNIP1
gene id: 32536:FNIP1
uniprot id: A0A6J2ARR1
uniprot id: A0A6J2AWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

32536:CDK8
gene id: 32536:CDK8
uniprot id: A0A6J0A6K2
uniprot id: A0A6J0A7P4
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:SLAIN1
gene id: 32536:SLAIN1
uniprot id: A0A6I9ZB91
uniprot id: A0A6J1ZTI3
uniprot id: A0A6J1ZUN2
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

32536:CTSH
gene id: 32536:CTSH
uniprot id: A0A6J2A2X1
uniprot id: A0A6J2A6V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

32536:CD5L
gene id: 32536:CD5L
uniprot id: A0A6J1YI04
uniprot id: A0A6J1YIS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SEMA3A
gene id: 32536:SEMA3A
uniprot id: A0A6I9ZPF6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CLDN5
gene id: 32536:CLDN5
uniprot id: A0A6J1YMQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

32536:SMG9
gene id: 32536:SMG9
uniprot id: A0A6J1XLV9
uniprot id: A0A6J1XM47
names: Similarity
messages: Belongs to the SMG9 family.

32536:MTERF3
gene id: 32536:MTERF3
uniprot id: A0A6J0A258
uniprot id: A0A6J1ZR45
names: Similarity
messages: Belongs to the mTERF family.

32536:PPP2R2B
gene id: 32536:PPP2R2B
uniprot id: A0A6J1XZC5
uniprot id: A0A6J1XZJ2
uniprot id: A0A6J1XZM9
uniprot id: A0A6J1XZP2
uniprot id: A0A6J1XZW1
uniprot id: A0A6J1XZW9
uniprot id: A0A6J1XZY9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

32536:CCN1
gene id: 32536:CCN1
uniprot id: A0A6J1ZBS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:ITGB1
gene id: 32536:ITGB1
uniprot id: A0A6J2AJJ6
uniprot id: A0A6J2AM08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Recycling endosome
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle membrane

32536:HTRA1
gene id: 32536:HTRA1
uniprot id: A0A6J1ZPK4
names: Similarity
messages: Belongs to the peptidase S1C family.

32536:TSPAN32
gene id: 32536:TSPAN32
uniprot id: A0A6J1Y8E0
uniprot id: A0A6J1Y8G8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:KCNK6
gene id: 32536:KCNK6
uniprot id: A0A6J1Y631
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:LOC106979746
gene id: 32536:LOC106979746
uniprot id: A0A6J2ALE6
uniprot id: A0A6J2AN19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

32536:TMEM144
gene id: 32536:TMEM144
uniprot id: A0A6J2A5Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

32536:CRHR2
gene id: 32536:CRHR2
uniprot id: A0A6J2AM05
uniprot id: A0A6J2ANQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Membrane

32536:CTSE
gene id: 32536:CTSE
uniprot id: A0A6I9ZPJ6
uniprot id: A0A6I9ZQX4
names: Similarity
messages: Belongs to the peptidase A1 family.

32536:RPF2
gene id: 32536:RPF2
uniprot id: A0A6J1Z6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

32536:LLGL1
gene id: 32536:LLGL1
uniprot id: A0A6J1YF64
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

32536:LOC106985917
gene id: 32536:LOC106985917
uniprot id: A0A6J0A6V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PTGR2
gene id: 32536:PTGR2
uniprot id: A0A6I9ZNB6
uniprot id: A0A6J2A0M5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

32536:ETFRF1
gene id: 32536:ETFRF1
uniprot id: A0A6I9ZFP0
names: Similarity
messages: Belongs to the complex I LYR family.

32536:ADCK1
gene id: 32536:ADCK1
uniprot id: A0A6I9ZRN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

32536:UBE2F
gene id: 32536:UBE2F
uniprot id: A0A6J1YB71
uniprot id: A0A6J1YBU7
uniprot id: A0A6J1YD65
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:TMEM14A
gene id: 32536:TMEM14A
uniprot id: A0A6I9ZR58
names: Similarity
messages: Belongs to the TMEM14 family.

32536:RABEP2
gene id: 32536:RABEP2
uniprot id: A0A6J1YQF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Cytoplasm
messages: Early endosome
messages: Endosome

32536:CTNNA1
gene id: 32536:CTNNA1
uniprot id: A0A6J2AQT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

32536:SF3B1
gene id: 32536:SF3B1
uniprot id: A0A6I9ZXV5
uniprot id: A0A6J1YX84
uniprot id: A0A6J1Z0M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

32536:MEX3B
gene id: 32536:MEX3B
uniprot id: A0A6J2A600
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:ELL3
gene id: 32536:ELL3
uniprot id: A0A6I9ZI29
uniprot id: A0A6J1ZZQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

32536:LOC106985879
gene id: 32536:LOC106985879
uniprot id: A0A6J0A491
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SH3RF2
gene id: 32536:SH3RF2
uniprot id: A0A6J0A6A8
uniprot id: A0A6J1XZX4
names: Similarity
messages: Belongs to the SH3RF family.

32536:NLRP14
gene id: 32536:NLRP14
uniprot id: A0A6J2AI15
names: Similarity
messages: Belongs to the NLRP family.

32536:POP5
gene id: 32536:POP5
uniprot id: A0A6I9ZMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

32536:LOC106977875
gene id: 32536:LOC106977875
uniprot id: A0A6I9ZXX2
names: Similarity
messages: Belongs to the MS4A family.

32536:CD200
gene id: 32536:CD200
uniprot id: A0A6J2AU11
uniprot id: A0A6J2AUH1
uniprot id: A0A6J2AYK9
names: Subcellular Location Annotation
messages: Cell membrane

32536:TMEM200B
gene id: 32536:TMEM200B
uniprot id: A0A6J1ZF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

32536:NEXMIF
gene id: 32536:NEXMIF
uniprot id: A0A6J1YXV8
names: Subcellular Location Annotation
messages: Nucleus

32536:CBR4
gene id: 32536:CBR4
uniprot id: A0A6J2A7H8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:SDR16C5
gene id: 32536:SDR16C5
uniprot id: A0A6J1Y1Q2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:SLC37A3
gene id: 32536:SLC37A3
uniprot id: A0A6J2ANH7
uniprot id: A0A6J2ASP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

32536:NDUFS6
gene id: 32536:NDUFS6
uniprot id: A0A6J2ALY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

32536:CLDN14
gene id: 32536:CLDN14
uniprot id: A0A6I9ZEF0
uniprot id: A0A6J1XXX4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

32536:SLX9
gene id: 32536:SLX9
uniprot id: A0A6J1XXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLX9 family.
messages: nucleolus

32536:CPB1
gene id: 32536:CPB1
uniprot id: A0A6J1ZMH7
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:GPR83
gene id: 32536:GPR83
uniprot id: A0A6J1XTW2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:LOC106969830
gene id: 32536:LOC106969830
uniprot id: A0A6I9ZJT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ADAM28
gene id: 32536:ADAM28
uniprot id: A0A6J2AT28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SLC12A7
gene id: 32536:SLC12A7
uniprot id: A0A6J2AH28
uniprot id: A0A6J2AHH8
uniprot id: A0A6J2AIM1
uniprot id: A0A6J2ALF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

32536:ABR
gene id: 32536:ABR
uniprot id: A0A6I9ZIE7
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

32536:PLAC8L1
gene id: 32536:PLAC8L1
uniprot id: A0A6J0A5Z1
uniprot id: A0A6J0A724
names: Similarity
messages: Belongs to the cornifelin family.

32536:BAZ2B
gene id: 32536:BAZ2B
uniprot id: A0A6J1Z5D5
names: Similarity
messages: Belongs to the WAL family.

32536:FAM219A
gene id: 32536:FAM219A
uniprot id: A0A6J1XRF2
uniprot id: A0A6J1XRG4
uniprot id: A0A6J1XRM2
uniprot id: A0A6J1XRM6
uniprot id: A0A6J1XRP1
uniprot id: A0A6J1XRT7
names: Similarity
messages: Belongs to the FAM219 family.

32536:LOC106976562
gene id: 32536:LOC106976562
uniprot id: A0A6I9ZUZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106984988
gene id: 32536:LOC106984988
uniprot id: A0A6J0A3B5
names: Subcellular Location Annotation
messages: Nucleus

32536:LYSET
gene id: 32536:LYSET
uniprot id: A0A6J0A284
uniprot id: A0A6J1ZXG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LYSET family.
messages: Membrane

32536:AP1B1
gene id: 32536:AP1B1
uniprot id: A0A6J0A3U7
uniprot id: A0A6J0A6G6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

32536:ATG9A
gene id: 32536:ATG9A
uniprot id: A0A6J1YL78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

32536:PRR5L
gene id: 32536:PRR5L
uniprot id: A0A6J2AGW6
names: Similarity
messages: Belongs to the PROTOR family.

32536:ITGA11
gene id: 32536:ITGA11
uniprot id: A0A6J2A4U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

32536:TSSC4
gene id: 32536:TSSC4
uniprot id: A0A6J1Y975
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TSSC4 family.
messages: Cytoplasm
messages: Nucleus

32536:THBD
gene id: 32536:THBD
uniprot id: A0A6J0A7G6
names: Function
names: Subunit
messages: Interacts with ITGAL, ITGAM and ITGB2.
messages: Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

32536:POLR2G
gene id: 32536:POLR2G
uniprot id: A0A6J1Y966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

32536:ASXL3
gene id: 32536:ASXL3
uniprot id: A0A6J2A423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

32536:ORC4
gene id: 32536:ORC4
uniprot id: A0A6I9ZL44
uniprot id: A0A6I9ZPW3
uniprot id: A0A6J1Z2D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

32536:SEC13
gene id: 32536:SEC13
uniprot id: A0A6I9ZMA8
uniprot id: A0A6J1Y0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane

32536:GTF2F1
gene id: 32536:GTF2F1
uniprot id: A0A6J1YMD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

32536:ATPSCKMT
gene id: 32536:ATPSCKMT
uniprot id: A0A6J2AJ51
uniprot id: A0A6J2AJQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

32536:CD8B
gene id: 32536:CD8B
uniprot id: A0A6I9ZTU1
names: Subcellular Location Annotation
messages: Membrane

32536:APOA2
gene id: 32536:APOA2
uniprot id: A0A6J1YJK8
uniprot id: P0DP50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein A2 family.
messages: May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
messages: Monomer. Interacts with NAXE and NDRG1 (By similarity).
messages: Monomer. Interacts with NAXE and NDRG1.
messages: Secreted

32536:FAR1
gene id: 32536:FAR1
uniprot id: A0A6J2AG03
uniprot id: A0A6J2AGG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

32536:SLC39A7
gene id: 32536:SLC39A7
uniprot id: A0A6I9ZQV4
uniprot id: A0A6I9ZU89
names: Subcellular Location Annotation
messages: Membrane

32536:METTL2A
gene id: 32536:METTL2A
uniprot id: A0A6J1YFX9
uniprot id: A0A6J1YGG4
uniprot id: A0A6J1YH80
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

32536:UBE2T
gene id: 32536:UBE2T
uniprot id: A0A6J2AQ43
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:SGSM1
gene id: 32536:SGSM1
uniprot id: A0A6J1YNG7
uniprot id: A0A6J1YNH1
uniprot id: A0A6J1YRG7
names: Similarity
messages: Belongs to the RUTBC family.

32536:LOC106986197
gene id: 32536:LOC106986197
uniprot id: A0A6J0A7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ANXA7
gene id: 32536:ANXA7
uniprot id: A0A6I9ZNC4
uniprot id: A0A6J1ZPC6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

32536:ZDHHC15
gene id: 32536:ZDHHC15
uniprot id: A0A6J1YXS0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:LOC106978148
gene id: 32536:LOC106978148
uniprot id: A0A6I9ZTT6
uniprot id: A0A6I9ZXF7
uniprot id: A0A6I9ZYE8
uniprot id: A0A6J1XAR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

32536:STRIP2
gene id: 32536:STRIP2
uniprot id: A0A6J2AN28
uniprot id: A0A6J2APE9
uniprot id: A0A6J2AS74
names: Similarity
messages: Belongs to the STRIP family.

32536:B4GALT3
gene id: 32536:B4GALT3
uniprot id: A0A6J1YI31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

32536:FAM210A
gene id: 32536:FAM210A
uniprot id: A0A6I9ZWA7
names: Similarity
messages: Belongs to the FAM210 family.

32536:ANKS1A
gene id: 32536:ANKS1A
uniprot id: A0A6J1Z894
uniprot id: A0A6J1Z932
uniprot id: A0A6J1Z9K0
uniprot id: A0A6J1ZAF5
uniprot id: A0A6J1ZAG0
uniprot id: A0A6J1ZBS3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

32536:GAPDH
gene id: 32536:GAPDH
uniprot id: A0A6J2AN27
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

32536:LOC106987340
gene id: 32536:LOC106987340
uniprot id: A0A6J1XDB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TXNRD2
gene id: 32536:TXNRD2
uniprot id: A0A6J1YK67
uniprot id: A0A6J1YK73
uniprot id: A0A6J1YK78
uniprot id: A0A6J1YK80
uniprot id: A0A6J1YLU0
uniprot id: A0A6J1YMT6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

32536:PDRG1
gene id: 32536:PDRG1
uniprot id: A0A6I9ZTC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.

32536:SH3GLB1
gene id: 32536:SH3GLB1
uniprot id: A0A6J1ZAC6
uniprot id: A0A6J1ZB70
uniprot id: A0A6J1ZCL6
uniprot id: A0A6J1ZDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Golgi apparatus membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: autophagosome membrane

32536:STARD5
gene id: 32536:STARD5
uniprot id: A0A6J2A3P8
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

32536:LOC106965731
gene id: 32536:LOC106965731
uniprot id: A0A6I9ZCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:HPSE2
gene id: 32536:HPSE2
uniprot id: A0A6J1ZQZ2
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

32536:VPS16
gene id: 32536:VPS16
uniprot id: A0A6J2A6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

32536:NDUFAF4
gene id: 32536:NDUFAF4
uniprot id: A0A6J0A0S1
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

32536:ZNF622
gene id: 32536:ZNF622
uniprot id: A0A6I9ZLN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

32536:CD99
gene id: 32536:CD99
uniprot id: A0A6J1YVV7
uniprot id: A0A6J1YXB5
names: Similarity
messages: Belongs to the CD99 family.

32536:KRTCAP3
gene id: 32536:KRTCAP3
uniprot id: A0A6J1XA43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

32536:UBE2S
gene id: 32536:UBE2S
uniprot id: A0A6J1XL51
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:TRHDE
gene id: 32536:TRHDE
uniprot id: A0A6J2AF88
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

32536:KCNK12
gene id: 32536:KCNK12
uniprot id: A0A6J2AIS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:E2F1
gene id: 32536:E2F1
uniprot id: A0A6J2AAW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

32536:REM2
gene id: 32536:REM2
uniprot id: A0A6J0A7H0
names: Subcellular Location Annotation
messages: Cell membrane

32536:MED24
gene id: 32536:MED24
uniprot id: A0A6J1XAX6
uniprot id: A0A6J1XAY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

32536:CXCL12
gene id: 32536:CXCL12
uniprot id: A0A6J1ZLK8
uniprot id: A0A6J1ZLW8
names: Similarity
messages: Belongs to the intercrine alpha (chemokine CxC) family.

32536:ELP2
gene id: 32536:ELP2
uniprot id: A0A6J0A5L3
uniprot id: A0A6J2A581
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

32536:LOC106986632
gene id: 32536:LOC106986632
uniprot id: A0A6J0A8X1
names: Subcellular Location Annotation
messages: Secreted

32536:FGG
gene id: 32536:FGG
uniprot id: A0A6J0A357
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

32536:LOC106975012
gene id: 32536:LOC106975012
uniprot id: A0A6I9ZSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:UBE2A
gene id: 32536:UBE2A
uniprot id: A0A6J1YXW1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:SNTB1
gene id: 32536:SNTB1
uniprot id: A0A6J1ZT46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

32536:MTIF2
gene id: 32536:MTIF2
uniprot id: A0A6I9ZWU2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

32536:GCNT1
gene id: 32536:GCNT1
uniprot id: A0A6J1XW51
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

32536:GJB2
gene id: 32536:GJB2
uniprot id: A0A6J1ZT25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

32536:NDUFA13
gene id: 32536:NDUFA13
uniprot id: A0A6I9ZHK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

32536:SEPTIN2
gene id: 32536:SEPTIN2
uniprot id: A0A6J1Y8W3
uniprot id: A0A6J1YAQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Filament-forming cytoskeletal GTPase.
messages: Midbody
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.
messages: cilium membrane
messages: flagellum
messages: spindle

32536:NDUFS7
gene id: 32536:NDUFS7
uniprot id: A0A6J1YM98
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

32536:LOC106979689
gene id: 32536:LOC106979689
uniprot id: A0A6I9ZWD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

32536:CRELD2
gene id: 32536:CRELD2
uniprot id: A0A6J2ACG3
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:GPRASP2
gene id: 32536:GPRASP2
uniprot id: A0A6J1YWT2
names: Similarity
messages: Belongs to the GPRASP family.

32536:RECQL
gene id: 32536:RECQL
uniprot id: A0A6I9ZEK1
uniprot id: A0A6I9ZG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

32536:PLD1
gene id: 32536:PLD1
uniprot id: A0A6J1ZIA8
uniprot id: A0A6J1ZIB3
uniprot id: A0A6J1ZLW1
names: Similarity
messages: Belongs to the phospholipase D family.

32536:CHPT1
gene id: 32536:CHPT1
uniprot id: A0A6J2AE34
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

32536:HNRNPD
gene id: 32536:HNRNPD
uniprot id: A0A6J1ZC87
uniprot id: A0A6J1ZC93
uniprot id: A0A6J1ZDI7
uniprot id: A0A6J1ZDK6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:GPN3
gene id: 32536:GPN3
uniprot id: A0A6I9ZF89
uniprot id: A0A6I9ZII4
uniprot id: A0A6J1Y5M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

32536:LEPROTL1
gene id: 32536:LEPROTL1
uniprot id: A0A6J2AY12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

32536:CASP7
gene id: 32536:CASP7
uniprot id: A0A6J1ZQM6
names: Similarity
messages: Belongs to the peptidase C14A family.

32536:GDE1
gene id: 32536:GDE1
uniprot id: A0A6J1Y296
uniprot id: A0A6J1Y3U3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

32536:TDP1
gene id: 32536:TDP1
uniprot id: A0A6I9ZVD0
uniprot id: A0A6I9ZWV0
uniprot id: A0A6J1ZYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

32536:OXSR1
gene id: 32536:OXSR1
uniprot id: A0A6I9ZCG2
uniprot id: A0A6J1XV77
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

32536:TRAPPC3
gene id: 32536:TRAPPC3
uniprot id: A0A6I9ZQ21
uniprot id: A0A6J1ZFI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

32536:DIP2A
gene id: 32536:DIP2A
uniprot id: A0A6J1XX14
uniprot id: A0A6J1XX32
uniprot id: A0A6J1XX37
uniprot id: A0A6J1XXD6
uniprot id: A0A6J1XXE8
uniprot id: A0A6J1XY02
uniprot id: A0A6J1XY08
uniprot id: A0A6J1XY13
names: Similarity
messages: Belongs to the DIP2 family.

32536:HGH1
gene id: 32536:HGH1
uniprot id: A0A6J1ZS39
names: Similarity
messages: Belongs to the HGH1 family.

32536:PARD3
gene id: 32536:PARD3
uniprot id: A0A6J2AHV7
uniprot id: A0A6J2AHW3
uniprot id: A0A6J2AHW7
uniprot id: A0A6J2AHX0
uniprot id: A0A6J2AHX4
uniprot id: A0A6J2AHX8
uniprot id: A0A6J2AHY5
uniprot id: A0A6J2AIE4
uniprot id: A0A6J2AIE9
uniprot id: A0A6J2AIF7
uniprot id: A0A6J2AIG4
uniprot id: A0A6J2AIG9
uniprot id: A0A6J2AIH3
uniprot id: A0A6J2AIH8
uniprot id: A0A6J2AJL0
uniprot id: A0A6J2AJL5
uniprot id: A0A6J2AJL9
uniprot id: A0A6J2AJM3
uniprot id: A0A6J2AJM8
uniprot id: A0A6J2AM18
uniprot id: A0A6J2AM32
uniprot id: A0A6J2AM36
uniprot id: A0A6J2AM41
uniprot id: A0A6J2AME5
uniprot id: A0A6J2AMF0
uniprot id: A0A6J2AMF5
uniprot id: A0A6J2AMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

32536:MCIDAS
gene id: 32536:MCIDAS
uniprot id: A0A6J0A683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

32536:ADAMTS19
gene id: 32536:ADAMTS19
uniprot id: A0A6J2ARC1
uniprot id: A0A6J2AVN6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:SLC29A1
gene id: 32536:SLC29A1
uniprot id: A0A6J1Z7F7
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

32536:RAB18
gene id: 32536:RAB18
uniprot id: A0A6I9ZNT8
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

32536:LPIN2
gene id: 32536:LPIN2
uniprot id: A0A6J0A7C1
uniprot id: A0A6J2A3Q2
names: Similarity
messages: Belongs to the lipin family.

32536:LOC106966107
gene id: 32536:LOC106966107
uniprot id: A0A6I9ZD45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DUSP10
gene id: 32536:DUSP10
uniprot id: A0A6I9ZFJ0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

32536:BCCIP
gene id: 32536:BCCIP
uniprot id: A0A6I9ZPS4
uniprot id: A0A6J1ZPU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
messages: Nucleus
messages: spindle pole

32536:TRAF4
gene id: 32536:TRAF4
uniprot id: A0A6J1XCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

32536:CER1
gene id: 32536:CER1
uniprot id: A0A6I9ZWG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:INPP1
gene id: 32536:INPP1
uniprot id: A0A6J1Z2F0
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

32536:ITGB6
gene id: 32536:ITGB6
uniprot id: A0A6J0A2Z8
uniprot id: A0A6J0A612
uniprot id: A0A6J1Z368
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Membrane

32536:L3MBTL1
gene id: 32536:L3MBTL1
uniprot id: A0A6J2A7V2
uniprot id: A0A6J2A7X7
names: Subcellular Location Annotation
messages: Nucleus

32536:TDRD5
gene id: 32536:TDRD5
uniprot id: A0A6I9ZUT6
uniprot id: A0A6J2AJF7
uniprot id: A0A6J2AL26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDRD5 family.
messages: Cytoplasm
messages: Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly.

32536:HMX3
gene id: 32536:HMX3
uniprot id: A0A6J1ZJZ6
names: Subcellular Location Annotation
messages: Nucleus

32536:PHB1
gene id: 32536:PHB1
uniprot id: A0A6J0A3I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

32536:CAMK2N1
gene id: 32536:CAMK2N1
uniprot id: A0A6J1ZH84
names: Similarity
messages: Belongs to the CAMK2N family.

32536:SQSTM1
gene id: 32536:SQSTM1
uniprot id: A0A6J2ARU2
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

32536:APOA4
gene id: 32536:APOA4
uniprot id: A0A6J1XIN0
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

32536:SPAG7
gene id: 32536:SPAG7
uniprot id: A0A6J1YEU6
names: Subcellular Location Annotation
messages: Nucleus

32536:TFEB
gene id: 32536:TFEB
uniprot id: A0A6J1Z8L8
uniprot id: A0A6J1Z956
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

32536:FUT10
gene id: 32536:FUT10
uniprot id: A0A6I9ZGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

32536:GPD1L
gene id: 32536:GPD1L
uniprot id: A0A6J1XW02
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

32536:PARD6G
gene id: 32536:PARD6G
uniprot id: A0A6J2A5D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

32536:KRT222
gene id: 32536:KRT222
uniprot id: A0A6I9ZXQ7
uniprot id: A0A6J1XAV6
names: Similarity
messages: Belongs to the intermediate filament family.

32536:DYDC1
gene id: 32536:DYDC1
uniprot id: A0A6J1ZNK3
names: Similarity
messages: Belongs to the dpy-30 family.

32536:HEXB
gene id: 32536:HEXB
uniprot id: A0A6I9ZQI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

32536:LOC106971377
gene id: 32536:LOC106971377
uniprot id: A0A6I9ZJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

32536:F13B
gene id: 32536:F13B
uniprot id: A0A6J0A331
uniprot id: A0A6J2AKR9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SUPT20H
gene id: 32536:SUPT20H
uniprot id: A0A6J1ZSX3
uniprot id: A0A6J1ZWL0
names: Similarity
messages: Belongs to the SPT20 family.

32536:TAF1B
gene id: 32536:TAF1B
uniprot id: A0A6J0A9K4
uniprot id: A0A6J2AZQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.
messages: nucleolus

32536:RAB14
gene id: 32536:RAB14
uniprot id: A0A6J1XEA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

32536:ATP23
gene id: 32536:ATP23
uniprot id: A0A6J2ABH1
uniprot id: A0A6J2AF52
names: Similarity
messages: Belongs to the peptidase M76 family.

32536:SLC10A7
gene id: 32536:SLC10A7
uniprot id: A0A6J0A1F9
uniprot id: A0A6J0A4Q5
uniprot id: A0A6J1ZYY4
uniprot id: A0A6J1ZZQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

32536:CDT1
gene id: 32536:CDT1
uniprot id: A0A6J2AUM5
names: Similarity
messages: Belongs to the Cdt1 family.

32536:MSI2
gene id: 32536:MSI2
uniprot id: A0A6J1XBY6
uniprot id: A0A6J1XC04
uniprot id: A0A6J1XC07
uniprot id: A0A6J1XC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

32536:LOC106966068
gene id: 32536:LOC106966068
uniprot id: A0A6I9ZBM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GPKOW
gene id: 32536:GPKOW
uniprot id: A0A6J1Z0B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus
messages: RNA-binding protein involved in pre-mRNA splicing.

32536:NFRKB
gene id: 32536:NFRKB
uniprot id: A0A6J1XJP0
uniprot id: A0A6J1XJS8
names: Subcellular Location Annotation
messages: Nucleus

32536:MAT2A
gene id: 32536:MAT2A
uniprot id: A0A6J2AD40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

32536:SPP1
gene id: 32536:SPP1
uniprot id: A0A6I9ZR08
uniprot id: A0A6J1ZJ73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

32536:ADCY8
gene id: 32536:ADCY8
uniprot id: A0A6J1ZQ90
uniprot id: A0A6J1ZQK7
uniprot id: A0A6J1ZSW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

32536:SLC12A6
gene id: 32536:SLC12A6
uniprot id: A0A6J1ZYK6
uniprot id: A0A6J1ZYY9
uniprot id: A0A6J1ZZQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

32536:GPC6
gene id: 32536:GPC6
uniprot id: A0A6J0A6A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan.

32536:PTCD2
gene id: 32536:PTCD2
uniprot id: A0A6J1XU16
uniprot id: A0A6J1XUB1
uniprot id: A0A6J1XUG9
uniprot id: A0A6J1XUJ2
uniprot id: A0A6J1XUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTCD2 family.
messages: Mitochondrion

32536:PDCL
gene id: 32536:PDCL
uniprot id: A0A6J1XED9
names: Similarity
messages: Belongs to the phosducin family.

32536:SLC29A2
gene id: 32536:SLC29A2
uniprot id: A0A6J1YB48
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Lateral cell membrane
messages: Membrane

32536:EDNRB
gene id: 32536:EDNRB
uniprot id: A0A6I9ZE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:LOC106980041
gene id: 32536:LOC106980041
uniprot id: A0A6I9ZWZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

32536:SLC43A2
gene id: 32536:SLC43A2
uniprot id: A0A6J0A3X6
names: Subcellular Location Annotation
messages: Membrane

32536:ACAT1
gene id: 32536:ACAT1
uniprot id: A0A6J0A5E4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

32536:ANP32A
gene id: 32536:ANP32A
uniprot id: A0A6J2A0U5
uniprot id: A0A6J2A141
uniprot id: A0A6J2A1W8
uniprot id: A0A6J2A4U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

32536:TERF1
gene id: 32536:TERF1
uniprot id: A0A6J1ZRM2
uniprot id: A0A6J1ZSR4
uniprot id: A0A6J1ZUA3
uniprot id: A0A6J1ZVP4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus
messages: telomere

32536:ZIC3
gene id: 32536:ZIC3
uniprot id: A0A6J1YZD6
uniprot id: A0A6J1YZE2
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

32536:VIPR1
gene id: 32536:VIPR1
uniprot id: A0A6J1XVI8
uniprot id: A0A6J1XW05
uniprot id: A0A6J1XW10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

32536:KRT4
gene id: 32536:KRT4
uniprot id: A0A6J0A8L1
names: Similarity
messages: Belongs to the intermediate filament family.

32536:HAPLN2
gene id: 32536:HAPLN2
uniprot id: A0A6J1YJP6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:FUNDC2
gene id: 32536:FUNDC2
uniprot id: A0A6J1YUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

32536:GABRA3
gene id: 32536:GABRA3
uniprot id: A0A6I9ZKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:MCM6
gene id: 32536:MCM6
uniprot id: A0A6J1Z3T2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

32536:CPA2
gene id: 32536:CPA2
uniprot id: A0A6J2ARV1
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:TSPAN33
gene id: 32536:TSPAN33
uniprot id: A0A6J2AN23
uniprot id: A0A6J2AS69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:RGS5
gene id: 32536:RGS5
uniprot id: A0A6I9ZDT7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

32536:BCL2L13
gene id: 32536:BCL2L13
uniprot id: A0A6I9ZF23
uniprot id: A0A6J2AMB6
names: Similarity
messages: Belongs to the Bcl-2 family.

32536:TMEM132C
gene id: 32536:TMEM132C
uniprot id: A0A6J1Y614
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

32536:HOMER2
gene id: 32536:HOMER2
uniprot id: A0A6J2A2E2
uniprot id: A0A6J2A2N5
uniprot id: A0A6J2A6J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

32536:LPAR5
gene id: 32536:LPAR5
uniprot id: A0A6J2AJG6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:GRIK1
gene id: 32536:GRIK1
uniprot id: A0A6J1XY75
uniprot id: A0A6J1XY99
uniprot id: A0A6J1XYC5
uniprot id: A0A6J1XYN1
uniprot id: A0A6J1XZ74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:PITX3
gene id: 32536:PITX3
uniprot id: A0A6J1ZQ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

32536:STMN3
gene id: 32536:STMN3
uniprot id: A0A6J1YBU0
names: Similarity
messages: Belongs to the stathmin family.

32536:ESD
gene id: 32536:ESD
uniprot id: A0A6I9ZLQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

32536:POLR3C
gene id: 32536:POLR3C
uniprot id: A0A6J0A7A8
uniprot id: A0A6J0A830
uniprot id: A0A6J1YRH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

32536:MAPKAPK3
gene id: 32536:MAPKAPK3
uniprot id: A0A6J0A031
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:PCYOX1L
gene id: 32536:PCYOX1L
uniprot id: A0A6J2AS51
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

32536:SEC11C
gene id: 32536:SEC11C
uniprot id: A0A6I9ZZH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:ZDHHC22
gene id: 32536:ZDHHC22
uniprot id: A0A6I9ZPW0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:PIAS4
gene id: 32536:PIAS4
uniprot id: A0A6J1YIN4
uniprot id: A0A6J1YJK2
uniprot id: A0A6J1YK77
names: Similarity
messages: Belongs to the PIAS family.

32536:LZTFL1
gene id: 32536:LZTFL1
uniprot id: A0A6J1XP71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

32536:LOC106982931
gene id: 32536:LOC106982931
uniprot id: A0A6J0A4N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106987349
gene id: 32536:LOC106987349
uniprot id: A0A6J1XDG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CFHR5
gene id: 32536:CFHR5
uniprot id: A0A6J0A3E8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106986358
gene id: 32536:LOC106986358
uniprot id: A0A6J0A8I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DPH6
gene id: 32536:DPH6
uniprot id: A0A6J2A1N3
uniprot id: A0A6J2A2R9
names: Function
names: Similarity
messages: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
messages: Belongs to the Diphthine--ammonia ligase family.

32536:IL17B
gene id: 32536:IL17B
uniprot id: A0A6J2AW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

32536:MRPS36
gene id: 32536:MRPS36
uniprot id: A0A6I9ZTQ9
names: Subcellular Location Annotation
messages: Mitochondrion

32536:OSBPL1A
gene id: 32536:OSBPL1A
uniprot id: A0A6I9ZVN4
uniprot id: A0A6I9ZXX5
uniprot id: A0A6J2A4X1
uniprot id: A0A6J2A7F4
names: Similarity
messages: Belongs to the OSBP family.

32536:LOC106979393
gene id: 32536:LOC106979393
uniprot id: A0A6J2A1K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

32536:MAD1L1
gene id: 32536:MAD1L1
uniprot id: A0A6J1XZU8
uniprot id: A0A6J1Y047
uniprot id: A0A6J1Y075
uniprot id: A0A6J1Y0I4
uniprot id: A0A6J1Y121
names: Similarity
messages: Belongs to the MAD1 family.

32536:LOC106970934
gene id: 32536:LOC106970934
uniprot id: A0A6I9ZN90
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.

32536:CDC42EP5
gene id: 32536:CDC42EP5
uniprot id: A0A6J1XL17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

32536:LCN15
gene id: 32536:LCN15
uniprot id: A0A6J1YNT0
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

32536:RHOT1
gene id: 32536:RHOT1
uniprot id: A0A6J1XCL3
uniprot id: A0A6J1XCM4
uniprot id: A0A6J1XCM9
uniprot id: A0A6J1XCP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

32536:SS18L1
gene id: 32536:SS18L1
uniprot id: A0A6J1YBJ3
names: Similarity
messages: Belongs to the SS18 family.

32536:SYN2
gene id: 32536:SYN2
uniprot id: A0A6J1Y0M1
names: Similarity
messages: Belongs to the synapsin family.

32536:GATAD2B
gene id: 32536:GATAD2B
uniprot id: A0A6J1YHA5
names: Subcellular Location Annotation
messages: Nucleus

32536:NPPB
gene id: 32536:NPPB
uniprot id: A0A6I9ZJZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (By similarity). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3.
messages: Secreted

32536:GCFC2
gene id: 32536:GCFC2
uniprot id: A0A6I9ZPL2
uniprot id: A0A6J2AD90
names: Similarity
messages: Belongs to the GCF family.

32536:SEC31A
gene id: 32536:SEC31A
uniprot id: A0A6I9ZJ39
uniprot id: A0A6I9ZJ44
uniprot id: A0A6I9ZJ49
uniprot id: A0A6I9ZKQ5
uniprot id: A0A6I9ZKR0
uniprot id: A0A6I9ZM63
uniprot id: A0A6I9ZM69
uniprot id: A0A6I9ZM74
uniprot id: A0A6I9ZNP7
uniprot id: A0A6I9ZNQ2
uniprot id: A0A6I9ZNQ7
uniprot id: A0A6I9ZPD3
uniprot id: A0A6I9ZPD9
uniprot id: A0A6I9ZPE4
uniprot id: A0A6I9ZPE9
uniprot id: A0A6J1ZDJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

32536:INTS14
gene id: 32536:INTS14
uniprot id: A0A6I9ZY40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

32536:S100A6
gene id: 32536:S100A6
uniprot id: A0A6J1YJB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
messages: Nucleus envelope

32536:SRD5A1
gene id: 32536:SRD5A1
uniprot id: A0A6J2AKB4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

32536:MYO5A
gene id: 32536:MYO5A
uniprot id: A0A6J1ZZR8
uniprot id: A0A6J2A2T1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

32536:PKIG
gene id: 32536:PKIG
uniprot id: A0A6J2A816
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

32536:SLC19A2
gene id: 32536:SLC19A2
uniprot id: A0A6J1YCF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: High-affinity transporter for the intake of thiamine.

32536:OPTN
gene id: 32536:OPTN
uniprot id: A0A6J2AH04
uniprot id: A0A6J2AHE3
uniprot id: A0A6J2AIK5
uniprot id: A0A6J2AL16
uniprot id: A0A6J2AL21
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

32536:TPM2
gene id: 32536:TPM2
uniprot id: A0A6J0A1V5
uniprot id: A0A6J1XRQ2
uniprot id: A0A6J1XRY5
uniprot id: A0A6J1XS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

32536:PIWIL4
gene id: 32536:PIWIL4
uniprot id: A0A6J1XTE5
names: Similarity
messages: Belongs to the argonaute family.

32536:LOC106972035
gene id: 32536:LOC106972035
uniprot id: A0A6I9ZQM5
names: Similarity
messages: Belongs to the TMEM14 family.

32536:CYFIP2
gene id: 32536:CYFIP2
uniprot id: A0A6J2AU44
uniprot id: A0A6J2AUK2
uniprot id: A0A6J2AUK9
names: Similarity
messages: Belongs to the CYFIP family.

32536:MAPRE2
gene id: 32536:MAPRE2
uniprot id: A0A6J0A548
uniprot id: A0A6J0A681
uniprot id: A0A6J2A7S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

32536:BORA
gene id: 32536:BORA
uniprot id: A0A6J0A670
uniprot id: A0A6J1ZVX6
names: Similarity
messages: Belongs to the BORA family.

32536:NRG2
gene id: 32536:NRG2
uniprot id: A0A6I9ZGJ6
uniprot id: A0A6J2AQQ2
uniprot id: A0A6J2ASQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:UBA7
gene id: 32536:UBA7
uniprot id: A0A6I9ZVL3
uniprot id: A0A6I9ZZ17
uniprot id: A0A6J0A012
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

32536:LOC106986507
gene id: 32536:LOC106986507
uniprot id: A0A6J2AKX6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

32536:LUC7L
gene id: 32536:LUC7L
uniprot id: A0A6J1Y3K9
uniprot id: A0A6J1Y3S4
uniprot id: A0A6J1Y5I8
names: Similarity
messages: Belongs to the Luc7 family.

32536:PLAA
gene id: 32536:PLAA
uniprot id: A0A6J0A3V3
uniprot id: A0A6J0A4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PLAP family.
messages: Cytoplasm

32536:CORIN
gene id: 32536:CORIN
uniprot id: A0A6J1Z3T5
uniprot id: A0A6J1Z445
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CPD
gene id: 32536:CPD
uniprot id: A0A6J1XD34
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:RCAN1
gene id: 32536:RCAN1
uniprot id: A0A6I9ZDK4
uniprot id: A0A6J1XY07
names: Similarity
messages: Belongs to the RCAN family.

32536:PRKAR2B
gene id: 32536:PRKAR2B
uniprot id: A0A6J2ACD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

32536:SYNGR2
gene id: 32536:SYNGR2
uniprot id: A0A6J1YT60
uniprot id: A0A6J1YWE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

32536:ING2
gene id: 32536:ING2
uniprot id: A0A6J0A056
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

32536:HM13
gene id: 32536:HM13
uniprot id: A0A6J2A6X6
uniprot id: A0A6J2A7Q8
uniprot id: A0A6J2AB47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

32536:SCAMP2
gene id: 32536:SCAMP2
uniprot id: A0A6I9ZX08
uniprot id: A0A6J2A2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

32536:LOC106965701
gene id: 32536:LOC106965701
uniprot id: A0A6I9ZCM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:LOC106988070
gene id: 32536:LOC106988070
uniprot id: A0A6J1XU56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:DGKZ
gene id: 32536:DGKZ
uniprot id: A0A6J2AFJ3
uniprot id: A0A6J2AFJ9
uniprot id: A0A6J2AGM8
uniprot id: A0A6J2AJ64
uniprot id: A0A6J2AJJ5
uniprot id: A0A6J2AJK0
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

32536:TRPV3
gene id: 32536:TRPV3
uniprot id: A0A6J1XDD3
uniprot id: A0A6J1XDE1
uniprot id: A0A6J1XDF7
names: Subcellular Location Annotation
messages: Membrane

32536:WTAP
gene id: 32536:WTAP
uniprot id: A0A6J1Z5Q8
uniprot id: A0A6J1Z7Q0
names: Similarity
messages: Belongs to the fl(2)d family.

32536:PPIF
gene id: 32536:PPIF
uniprot id: A0A6J1ZNJ2
uniprot id: A0A6J1ZPV9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:PAX7
gene id: 32536:PAX7
uniprot id: A0A6J1ZF30
uniprot id: A0A6J1ZFE8
uniprot id: A0A6J1ZG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

32536:DSCC1
gene id: 32536:DSCC1
uniprot id: A0A6J0A6H0
uniprot id: A0A6J1ZUK6
names: Similarity
messages: Belongs to the DCC1 family.

32536:MAPK10
gene id: 32536:MAPK10
uniprot id: A0A6I9ZMW5
uniprot id: A0A6I9ZMX0
uniprot id: A0A6I9ZMX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

32536:RPS11
gene id: 32536:RPS11
uniprot id: A0A6J1XN16
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

32536:MFAP5
gene id: 32536:MFAP5
uniprot id: A0A6I9ZBZ8
uniprot id: A0A6I9ZDE8
uniprot id: A0A6I9ZF37
uniprot id: A0A6I9ZF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

32536:FGF11
gene id: 32536:FGF11
uniprot id: A0A6J1YF14
uniprot id: A0A6J1YF16
uniprot id: A0A6J1YH53
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:DTD1
gene id: 32536:DTD1
uniprot id: A0A6J2A604
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

32536:ACTR1B
gene id: 32536:ACTR1B
uniprot id: A0A6J2AIN5
names: Similarity
messages: Belongs to the actin family.

32536:DDX5
gene id: 32536:DDX5
uniprot id: A0A6I9ZUD9
uniprot id: A0A6J1YGM9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.

32536:SLC39A3
gene id: 32536:SLC39A3
uniprot id: A0A6J0A3B2
uniprot id: A0A6J1YL81
names: Subcellular Location Annotation
messages: Membrane

32536:STARD13
gene id: 32536:STARD13
uniprot id: A0A6I9ZSA0
uniprot id: A0A6I9ZT42
uniprot id: A0A6J1ZSE5
names: Subcellular Location Annotation
messages: Cytoplasm

32536:LOC106986012
gene id: 32536:LOC106986012
uniprot id: A0A6J1YMK1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

32536:CERS6
gene id: 32536:CERS6
uniprot id: A0A6I9ZJC0
uniprot id: A0A6I9ZMU9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

32536:LOC106974254
gene id: 32536:LOC106974254
uniprot id: A0A6J2AKE4
uniprot id: A0A6J2AL09
uniprot id: A0A6J2AL14
uniprot id: A0A6J2APK9
uniprot id: A0A6J2AQ32
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

32536:NRCAM
gene id: 32536:NRCAM
uniprot id: A0A6J2AC03
uniprot id: A0A6J2ACA1
uniprot id: A0A6J2AD86
uniprot id: A0A6J2AD94
uniprot id: A0A6J2AFW1
uniprot id: A0A6J2AFX6
uniprot id: A0A6J2AGE2
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

32536:NLRP13
gene id: 32536:NLRP13
uniprot id: A0A6J1XKK3
names: Similarity
messages: Belongs to the NLRP family.

32536:SEMA3D
gene id: 32536:SEMA3D
uniprot id: A0A6J2ADL9
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106979339
gene id: 32536:LOC106979339
uniprot id: A0A6I9ZVR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NOTCH2
gene id: 32536:NOTCH2
uniprot id: A0A6J1Z950
uniprot id: A0A6J1ZAG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

32536:REEP2
gene id: 32536:REEP2
uniprot id: A0A6J2AST9
uniprot id: A0A6J2AV60
uniprot id: A0A6J2AVS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PDGFD
gene id: 32536:PDGFD
uniprot id: A0A6J1YRG0
uniprot id: A0A6J1YSW2
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:MAPRE3
gene id: 32536:MAPRE3
uniprot id: A0A6I9ZEA8
uniprot id: A0A6J1X9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

32536:ALKBH6
gene id: 32536:ALKBH6
uniprot id: A0A6J1Y6Q5
names: Similarity
messages: Belongs to the alkB family.

32536:BAZ1A
gene id: 32536:BAZ1A
uniprot id: A0A6J1ZW62
uniprot id: A0A6J1ZZ36
names: Subcellular Location Annotation
messages: Nucleus

32536:GNG10
gene id: 32536:GNG10
uniprot id: A0A6J1XDQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:LOC106980914
gene id: 32536:LOC106980914
uniprot id: A0A0A0Y2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:RPL39
gene id: 32536:RPL39
uniprot id: A0A6J1YY03
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

32536:GNG4
gene id: 32536:GNG4
uniprot id: A0A6J0A4A0
uniprot id: A0A6J1YCL1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:HAMP
gene id: 32536:HAMP
uniprot id: A0A6J1Y7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hepcidin family.
messages: Secreted

32536:IL17D
gene id: 32536:IL17D
uniprot id: A0A6J1ZW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

32536:ATG5
gene id: 32536:ATG5
uniprot id: A0A6I9ZYG1
uniprot id: A0A6I9ZZE0
uniprot id: A0A6I9ZZG7
uniprot id: A0A6J1Z875
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

32536:YES1
gene id: 32536:YES1
uniprot id: A0A6J2A4S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:LOC106986214
gene id: 32536:LOC106986214
uniprot id: A0A6J0A7J1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SZRD1
gene id: 32536:SZRD1
uniprot id: A0A6J1ZF71
uniprot id: A0A6J1ZGC7
names: Similarity
messages: Belongs to the SZRD1 family.

32536:PRDX2
gene id: 32536:PRDX2
uniprot id: A0A6J1YP90
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

32536:PPP4R3B
gene id: 32536:PPP4R3B
uniprot id: A0A6I9ZVB5
uniprot id: A0A6I9ZWD3
uniprot id: A0A6J2AE62
uniprot id: A0A6J2AEH5
names: Similarity
messages: Belongs to the SMEK family.

32536:CTSB
gene id: 32536:CTSB
uniprot id: A0A6I9ZUZ7
uniprot id: A0A6I9ZVJ1
uniprot id: A0A6J2A9B4
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Lysosome

32536:RPLP1
gene id: 32536:RPLP1
uniprot id: A0A6J2A4W5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.

32536:NDUFAB1
gene id: 32536:NDUFAB1
uniprot id: A0A6J1Y3E8
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

32536:CLCN1
gene id: 32536:CLCN1
uniprot id: A0A6J2AQ67
names: Subcellular Location Annotation
messages: Membrane

32536:STK38L
gene id: 32536:STK38L
uniprot id: A0A6J1XGJ6
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:ACSL6
gene id: 32536:ACSL6
uniprot id: A0A6I9ZII2
uniprot id: A0A6J2AR96
uniprot id: A0A6J2ARP6
uniprot id: A0A6J2AT91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane

32536:SLC39A4
gene id: 32536:SLC39A4
uniprot id: A0A6J1ZQI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

32536:POLR2H
gene id: 32536:POLR2H
uniprot id: A0A6J0A4R4
names: Function
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.

32536:EXOC3L4
gene id: 32536:EXOC3L4
uniprot id: A0A6J1ZY23
names: Similarity
messages: Belongs to the SEC6 family.

32536:SARS1
gene id: 32536:SARS1
uniprot id: A0A6J1ZBX1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

32536:ABHD2
gene id: 32536:ABHD2
uniprot id: A0A6J2A1Z7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

32536:LOC106978991
gene id: 32536:LOC106978991
uniprot id: A0A6J1ZIC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:ALDH3B2
gene id: 32536:ALDH3B2
uniprot id: A0A6J1Y9A6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:LOC106989458
gene id: 32536:LOC106989458
uniprot id: A0A6J0ACD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MMP14
gene id: 32536:MMP14
uniprot id: A0A6J1ZUU3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Cytoplasm
messages: Melanosome

32536:CACYBP
gene id: 32536:CACYBP
uniprot id: A0A6J2AKV0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

32536:PPP2R5B
gene id: 32536:PPP2R5B
uniprot id: A0A6J1Y9R9
uniprot id: A0A6J1YAU0
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

32536:CDNF
gene id: 32536:CDNF
uniprot id: A0A6J2ALL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

32536:B4GALT7
gene id: 32536:B4GALT7
uniprot id: A0A6J2ARP1
uniprot id: A0A6J2AS41
uniprot id: A0A6J2AVZ9
uniprot id: A0A6J2AWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

32536:ELAVL3
gene id: 32536:ELAVL3
uniprot id: A0A6J1YLJ5
uniprot id: A0A6J1YLJ8
uniprot id: A0A6J1YN57
uniprot id: A0A6J1YPB6
names: Similarity
messages: Belongs to the RRM elav family.

32536:AQP6
gene id: 32536:AQP6
uniprot id: A0A6I9ZJ59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

32536:SMIM8
gene id: 32536:SMIM8
uniprot id: A0A6I9ZMF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM8 family.
messages: Membrane

32536:SUZ12
gene id: 32536:SUZ12
uniprot id: A0A6J0A6K0
uniprot id: A0A6J1XCP0
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

32536:SLC24A2
gene id: 32536:SLC24A2
uniprot id: A0A6J1YE07
uniprot id: A0A6J1YEK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

32536:ITGA1
gene id: 32536:ITGA1
uniprot id: A0A6I9ZSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

32536:SSH1
gene id: 32536:SSH1
uniprot id: A0A6J1Y4F8
uniprot id: A0A6J1Y560
uniprot id: A0A6J1Y652
uniprot id: A0A6J1Y657
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

32536:LOC106974502
gene id: 32536:LOC106974502
uniprot id: A0A6I9ZRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

32536:CLN3
gene id: 32536:CLN3
uniprot id: A0A6J1YQU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

32536:SOX14
gene id: 32536:SOX14
uniprot id: A0A6I9ZTF5
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106972801
gene id: 32536:LOC106972801
uniprot id: A0A6I9ZQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

32536:KALRN
gene id: 32536:KALRN
uniprot id: A0A6J1ZH69
uniprot id: A0A6J1ZH74
uniprot id: A0A6J1ZHG4
uniprot id: A0A6J1ZHG9
uniprot id: A0A6J1ZHH4
uniprot id: A0A6J1ZHI4
uniprot id: A0A6J1ZID3
uniprot id: A0A6J1ZID8
uniprot id: A0A6J1ZIE3
uniprot id: A0A6J1ZJK6
uniprot id: A0A6J1ZJL2
uniprot id: A0A6J1ZKM3
uniprot id: A0A6J1ZKN5
uniprot id: A0A6J1ZKP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm

32536:SMC5
gene id: 32536:SMC5
uniprot id: A0A6J1XWA8
uniprot id: A0A6J1XX41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

32536:TNFRSF14
gene id: 32536:TNFRSF14
uniprot id: A0A6J1ZJM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106981277
gene id: 32536:LOC106981277
uniprot id: A0A6J0A2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

32536:THBS3
gene id: 32536:THBS3
uniprot id: A0A6J1YIC1
uniprot id: A0A6J1YIY7
uniprot id: A0A6J1YJQ1
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CXCR4
gene id: 32536:CXCR4
uniprot id: A0A6I9ZL37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

32536:NCOA2
gene id: 32536:NCOA2
uniprot id: A0A6J1ZRQ5
uniprot id: A0A6J1ZS58
uniprot id: A0A6J1ZUF1
uniprot id: A0A6J1ZVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

32536:PHAX
gene id: 32536:PHAX
uniprot id: A0A6I9ZIJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

32536:NPC1
gene id: 32536:NPC1
uniprot id: A0A6J2A3Q3
uniprot id: A0A6J2A4V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

32536:EN2
gene id: 32536:EN2
uniprot id: A0A6J1YQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

32536:EIF4H
gene id: 32536:EIF4H
uniprot id: A0A6J1XYP6
uniprot id: A0A6J1XYU5
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

32536:LOC106986189
gene id: 32536:LOC106986189
uniprot id: A0A6J0A4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GRK3
gene id: 32536:GRK3
uniprot id: A0A6J1YQ42
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

32536:ETV3
gene id: 32536:ETV3
uniprot id: A0A6J1YHJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:UBA52
gene id: 32536:UBA52
uniprot id: A0A6I9ZHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

32536:TCF7L2
gene id: 32536:TCF7L2
uniprot id: A0A6J1ZMY8
uniprot id: A0A6J1ZMZ8
uniprot id: A0A6J1ZN25
uniprot id: A0A6J1ZN93
uniprot id: A0A6J1ZN98
uniprot id: A0A6J1ZNA5
uniprot id: A0A6J1ZNB1
uniprot id: A0A6J1ZNB6
uniprot id: A0A6J1ZND2
uniprot id: A0A6J1ZND7
uniprot id: A0A6J1ZP34
uniprot id: A0A6J1ZP40
uniprot id: A0A6J1ZP45
uniprot id: A0A6J1ZP73
uniprot id: A0A6J1ZP77
uniprot id: A0A6J1ZQH5
uniprot id: A0A6J1ZQI0
uniprot id: A0A6J1ZQI5
uniprot id: A0A6J1ZQI9
uniprot id: A0A6J1ZQK9
uniprot id: A0A6J1ZQL2
uniprot id: A0A6J1ZRS0
uniprot id: A0A6J1ZRS5
uniprot id: A0A6J1ZRT4
uniprot id: A0A6J1ZRT9
uniprot id: A0A6J1ZRU4
uniprot id: A0A6J1ZRV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

32536:PFKFB3
gene id: 32536:PFKFB3
uniprot id: A0A6J2AH79
uniprot id: A0A6J2AIE2
uniprot id: A0A6J2AL84
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

32536:EXOC3L1
gene id: 32536:EXOC3L1
uniprot id: A0A6I9ZJE3
uniprot id: A0A6I9ZKZ2
uniprot id: A0A6J2AP29
uniprot id: A0A6J2AR05
uniprot id: A0A6J2AT86
uniprot id: A0A6J2ATQ3
names: Similarity
messages: Belongs to the SEC6 family.

32536:TBC1D23
gene id: 32536:TBC1D23
uniprot id: A0A6I9ZGK7
uniprot id: A0A6I9ZHY7
names: Subcellular Location Annotation
messages: trans-Golgi network

32536:DONSON
gene id: 32536:DONSON
uniprot id: A0A6J1XY72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

32536:IL17RB
gene id: 32536:IL17RB
uniprot id: A0A6J0A8N2
uniprot id: A0A6J1XQJ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:IL5RA
gene id: 32536:IL5RA
uniprot id: A0A6I9ZGQ3
uniprot id: A0A6I9ZJH7
names: Subcellular Location Annotation
messages: Membrane

32536:XRCC1
gene id: 32536:XRCC1
uniprot id: A0A6I9ZS10
uniprot id: A0A6J1XLV3
names: Subcellular Location Annotation
messages: Nucleus

32536:SLC2A8
gene id: 32536:SLC2A8
uniprot id: A0A6J1XER0
uniprot id: A0A6J1XER5
uniprot id: A0A6J1XET7
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

32536:NADK2
gene id: 32536:NADK2
uniprot id: A0A6J2ARL2
uniprot id: A0A6J2AS18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAD kinase family.
messages: Homodimer.
messages: Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
messages: Mitochondrion

32536:LOC106966284
gene id: 32536:LOC106966284
uniprot id: A0A6I9ZDE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

32536:UTP18
gene id: 32536:UTP18
uniprot id: A0A6J1XBU0
uniprot id: A0A6J1XBU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

32536:ART1
gene id: 32536:ART1
uniprot id: A0A6J1XSU0
uniprot id: A0A6J1XSX4
uniprot id: A0A6J1XT14
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

32536:CD3H18orf32
gene id: 32536:CD3H18orf32
uniprot id: A0A6J2A4K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UPF0729 family.
messages: Interacts with DERL1 and AMFR.
messages: Lipid droplet
messages: May activate the NF-kappa-B signaling pathway.

32536:CDKL4
gene id: 32536:CDKL4
uniprot id: A0A6J1XAA4
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:ZNF197
gene id: 32536:ZNF197
uniprot id: A0A6J0A1Z4
uniprot id: A0A6J1XUN0
names: Subcellular Location Annotation
messages: Nucleus

32536:CCL19
gene id: 32536:CCL19
uniprot id: A0A6I9ZTN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:TMEM138
gene id: 32536:TMEM138
uniprot id: A0A6I9ZXW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

32536:DBR1
gene id: 32536:DBR1
uniprot id: A0A6I9ZRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

32536:RIMBP2
gene id: 32536:RIMBP2
uniprot id: A0A6J1Y571
uniprot id: A0A6J1Y576
uniprot id: A0A6J1Y6Y1
names: Similarity
messages: Belongs to the RIMBP family.

32536:TSPYL1
gene id: 32536:TSPYL1
uniprot id: A0A6J0A5K6
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

32536:GTF2E1
gene id: 32536:GTF2E1
uniprot id: A0A6J1ZJA3
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

32536:MAST1
gene id: 32536:MAST1
uniprot id: A0A6J1YNT3
uniprot id: A0A6J1YP44
uniprot id: A0A6J1YQB9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

32536:PAX8
gene id: 32536:PAX8
uniprot id: A0A6J1XAQ0
names: Subcellular Location Annotation
messages: Nucleus

32536:KCNK17
gene id: 32536:KCNK17
uniprot id: A0A6J1Z991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:SCGN
gene id: 32536:SCGN
uniprot id: A0A6J0ACA3
names: Subcellular Location Annotation
messages: secretory vesicle membrane

32536:ABCD4
gene id: 32536:ABCD4
uniprot id: A0A6J1ZWM5
uniprot id: A0A6J1ZWX6
uniprot id: A0A6J1ZWY1
uniprot id: A0A6J1ZZF2
uniprot id: A0A6J2A0P8
names: Subcellular Location Annotation
messages: Membrane

32536:TAMM41
gene id: 32536:TAMM41
uniprot id: A0A6I9ZXC9
uniprot id: A0A6J1Y0Y3
uniprot id: A0A6J1Y0Y7
uniprot id: A0A6J1Y124
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

32536:CD47
gene id: 32536:CD47
uniprot id: A0A6J2ATW4
uniprot id: A0A6J2AUA9
uniprot id: A0A6J2AVZ0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:SPTAN1
gene id: 32536:SPTAN1
uniprot id: A0A6J1XF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

32536:TMEM88
gene id: 32536:TMEM88
uniprot id: A0A6J1YGF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

32536:MFSD5
gene id: 32536:MFSD5
uniprot id: A0A6J0A7I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane

32536:EIF1
gene id: 32536:EIF1
uniprot id: A0A6J1YI09
names: Similarity
messages: Belongs to the SUI1 family.

32536:ZHX1
gene id: 32536:ZHX1
uniprot id: A0A6J1ZT22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

32536:ABCG5
gene id: 32536:ABCG5
uniprot id: A0A6I9ZVL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

32536:INSL3
gene id: 32536:INSL3
uniprot id: A0A6J1XNT9
uniprot id: A0A6J1XNW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

32536:CLN5
gene id: 32536:CLN5
uniprot id: A0A6J1ZUJ3
names: Similarity
messages: Belongs to the CLN5 family.

32536:YDJC
gene id: 32536:YDJC
uniprot id: A0A6J0ABP9
uniprot id: A0A6J1YKA2
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

32536:DDIT3
gene id: 32536:DDIT3
uniprot id: A0A6I9ZQF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Cytoplasm

32536:ADRA2B
gene id: 32536:ADRA2B
uniprot id: A0A6I9ZQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
messages: Cell membrane
messages: Membrane

32536:PLA2G2D
gene id: 32536:PLA2G2D
uniprot id: A0A6J1ZEY8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

32536:LRRFIP1
gene id: 32536:LRRFIP1
uniprot id: A0A6J0A7X6
uniprot id: A0A6J0A835
uniprot id: A0A6J1YBE8
uniprot id: A0A6J1YBH9
uniprot id: A0A6J1YBJ5
uniprot id: A0A6J1YBK6
uniprot id: A0A6J1YBL3
uniprot id: A0A6J1YBL4
uniprot id: A0A6J1YBN1
uniprot id: A0A6J1YBP7
uniprot id: A0A6J1YBP8
uniprot id: A0A6J1YBQ2
uniprot id: A0A6J1YBS5
uniprot id: A0A6J1YBT0
uniprot id: A0A6J1YBT6
uniprot id: A0A6J1YBU8
uniprot id: A0A6J1YBV3
uniprot id: A0A6J1YBV8
uniprot id: A0A6J1YBW9
uniprot id: A0A6J1YC06
uniprot id: A0A6J1YC14
uniprot id: A0A6J1YC22
uniprot id: A0A6J1YC27
uniprot id: A0A6J1YC32
uniprot id: A0A6J1YC44
uniprot id: A0A6J1YC77
uniprot id: A0A6J1YCC6
uniprot id: A0A6J1YCL0
uniprot id: A0A6J1YCL3
uniprot id: A0A6J1YCP9
uniprot id: A0A6J1YCQ6
uniprot id: A0A6J1YCU8
uniprot id: A0A6J1YCV8
uniprot id: A0A6J1YD76
uniprot id: A0A6J1YDA1
uniprot id: A0A6J1YDB9
uniprot id: A0A6J1YDD7
uniprot id: A0A6J1YDF2
uniprot id: A0A6J1YDP2
uniprot id: A0A6J1YDX6
uniprot id: A0A6J1YE28
uniprot id: A0A6J1YE59
names: Similarity
messages: Belongs to the LRRFIP family.

32536:CD79A
gene id: 32536:CD79A
uniprot id: A0A6J1XLZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:ZDHHC18
gene id: 32536:ZDHHC18
uniprot id: A0A6J1ZFE2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:GRM8
gene id: 32536:GRM8
uniprot id: A0A6J2APA2
uniprot id: A0A6J2AS26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

32536:DAG1
gene id: 32536:DAG1
uniprot id: A0A6J1XPZ3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

32536:MAP3K11
gene id: 32536:MAP3K11
uniprot id: A0A6J1Y875
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

32536:GRM2
gene id: 32536:GRM2
uniprot id: A0A6J0A8F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

32536:URAD
gene id: 32536:URAD
uniprot id: A0A6J1ZUW9
names: Function
names: Similarity
messages: Belongs to the OHCU decarboxylase family.
messages: Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

32536:LOC106980736
gene id: 32536:LOC106980736
uniprot id: A0A6J0A1S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MBOAT2
gene id: 32536:MBOAT2
uniprot id: A0A6J2AUR7
names: Subcellular Location Annotation
messages: Membrane

32536:CD93
gene id: 32536:CD93
uniprot id: A0A6J0AA34
uniprot id: A0A6J0AB49
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ZC2HC1C
gene id: 32536:ZC2HC1C
uniprot id: A0A6J1ZX00
names: Similarity
messages: Belongs to the ZC2HC1 family.

32536:PXMP2
gene id: 32536:PXMP2
uniprot id: A0A6J1YTC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

32536:CHST9
gene id: 32536:CHST9
uniprot id: A0A6J2A3U0
uniprot id: A0A6J2A3Y2
uniprot id: A0A6J2A4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:KAT8
gene id: 32536:KAT8
uniprot id: A0A6I9ZWJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

32536:DNAJC24
gene id: 32536:DNAJC24
uniprot id: A0A6I9ZHQ2
uniprot id: A0A6I9ZMB6
names: Similarity
messages: Belongs to the DPH4 family.

32536:IL15RA
gene id: 32536:IL15RA
uniprot id: A0A6J2AH68
uniprot id: A0A6J2AIC4
uniprot id: A0A6J2AKT8
uniprot id: A0A6J2AL73
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LCA5L
gene id: 32536:LCA5L
uniprot id: A0A6J1XXZ3
uniprot id: A0A6J1XY58
uniprot id: A0A6J1XYQ5
names: Similarity
messages: Belongs to the LCA5 family.

32536:VPS37B
gene id: 32536:VPS37B
uniprot id: A0A6J1Y587
uniprot id: A0A6J1Y6Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

32536:ABHD1
gene id: 32536:ABHD1
uniprot id: A0A6I9ZFU5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

32536:BRINP2
gene id: 32536:BRINP2
uniprot id: A0A6J2AJA7
names: Similarity
messages: Belongs to the BRINP family.

32536:STX3
gene id: 32536:STX3
uniprot id: A0A6J1Y920
names: Similarity
messages: Belongs to the syntaxin family.

32536:HCAR1
gene id: 32536:HCAR1
uniprot id: A0A6I9ZGU5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:CXCL16
gene id: 32536:CXCL16
uniprot id: A0A6J1YGZ6
names: Subcellular Location Annotation
messages: Membrane

32536:CLRN2
gene id: 32536:CLRN2
uniprot id: A0A6J0A592
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

32536:TADA3
gene id: 32536:TADA3
uniprot id: A0A6I9ZQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

32536:PRICKLE2
gene id: 32536:PRICKLE2
uniprot id: A0A6J1XR83
uniprot id: A0A6J1XRD4
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

32536:ACVR1
gene id: 32536:ACVR1
uniprot id: A0A6I9ZV30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

32536:PIP4P1
gene id: 32536:PIP4P1
uniprot id: A0A6J1ZU83
uniprot id: A0A6J1ZYE5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

32536:KIF21A
gene id: 32536:KIF21A
uniprot id: A0A6J1XGR7
uniprot id: A0A6J1XGS2
uniprot id: A0A6J1XGT3
uniprot id: A0A6J1XGT6
uniprot id: A0A6J1XGU4
uniprot id: A0A6J1XGU7
uniprot id: A0A6J1XGV2
uniprot id: A0A6J1XGX2
uniprot id: A0A6J1XGX8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:ARG1
gene id: 32536:ARG1
uniprot id: A0A6I9ZR49
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

32536:FOXE1
gene id: 32536:FOXE1
uniprot id: A0A6J1XS08
names: Subcellular Location Annotation
messages: Nucleus

32536:KPNA7
gene id: 32536:KPNA7
uniprot id: A0A6J1Y007
uniprot id: A0A6J1Y0J2
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

32536:FGD6
gene id: 32536:FGD6
uniprot id: A0A6I9ZRP0
uniprot id: A0A6J2ABJ2
names: Subcellular Location Annotation
messages: cytoskeleton

32536:LOC106976595
gene id: 32536:LOC106976595
uniprot id: A0A6I9ZWJ4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PDE2A
gene id: 32536:PDE2A
uniprot id: A0A6J1XSN4
uniprot id: A0A6J1XSZ8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:SLC4A3
gene id: 32536:SLC4A3
uniprot id: A0A6J1YK44
uniprot id: A0A6J1YK48
uniprot id: A0A6J1YK65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

32536:RAB3A
gene id: 32536:RAB3A
uniprot id: A0A6I9ZGA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

32536:OAZ1
gene id: 32536:OAZ1
uniprot id: A0A6J1YJM1
names: Similarity
messages: Belongs to the ODC antizyme family.

32536:MRPL4
gene id: 32536:MRPL4
uniprot id: A0A6J1YQ41
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

32536:KRT18
gene id: 32536:KRT18
uniprot id: A0A6J0A7S6
names: Similarity
messages: Belongs to the intermediate filament family.

32536:SLC16A1
gene id: 32536:SLC16A1
uniprot id: A0A6J1ZAM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

32536:LOC106981188
gene id: 32536:LOC106981188
uniprot id: A0A6I9ZYJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:BRI3
gene id: 32536:BRI3
uniprot id: A0A6J1Z0J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

32536:SPA17
gene id: 32536:SPA17
uniprot id: A0A6J1XJL5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

32536:HSPA5
gene id: 32536:HSPA5
uniprot id: A0A6J1XEJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cell surface
messages: Endoplasmic reticulum lumen
messages: Melanosome

32536:PRLHR
gene id: 32536:PRLHR
uniprot id: A0A6J0A5H9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:TAGLN
gene id: 32536:TAGLN
uniprot id: A0A6J1XJ17
names: Similarity
messages: Belongs to the calponin family.

32536:MSLN
gene id: 32536:MSLN
uniprot id: A0A6J1Y3E9
uniprot id: A0A6J1Y3M8
names: Similarity
messages: Belongs to the mesothelin family.

32536:PSME3
gene id: 32536:PSME3
uniprot id: A0A6I9ZP74
uniprot id: A0A6J1YK58
names: Similarity
messages: Belongs to the PA28 family.

32536:TMPRSS5
gene id: 32536:TMPRSS5
uniprot id: A0A6J1XIQ9
uniprot id: A0A6J1XIR5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:HIGD1C
gene id: 32536:HIGD1C
uniprot id: A0A6I9ZHQ5
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

32536:ZNF449
gene id: 32536:ZNF449
uniprot id: A0A6J1Z1B6
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106971354
gene id: 32536:LOC106971354
uniprot id: A0A6I9ZMA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PDGFC
gene id: 32536:PDGFC
uniprot id: A0A6I9ZQJ0
names: Caution
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PHLDA3
gene id: 32536:PHLDA3
uniprot id: A0A6J2AQ07
names: Subcellular Location Annotation
messages: Cytoplasm

32536:MESD
gene id: 32536:MESD
uniprot id: A0A6I9ZBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

32536:UBE2E1
gene id: 32536:UBE2E1
uniprot id: A0A6J1XWA9
uniprot id: A0A6J1XWD7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:MAP2K5
gene id: 32536:MAP2K5
uniprot id: A0A6I9ZYA5
uniprot id: A0A6I9ZYB0
uniprot id: A0A6J0A0R0
uniprot id: A0A6J2A0S6
uniprot id: A0A6J2A3T4
uniprot id: A0A6J2A3T9
uniprot id: A0A6J2A4S6
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:UGCG
gene id: 32536:UGCG
uniprot id: A0A6J1XDR2
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

32536:DDX27
gene id: 32536:DDX27
uniprot id: A0A6J0A7A2
uniprot id: A0A6J0A822
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:ERBB4
gene id: 32536:ERBB4
uniprot id: A0A6J1YQN1
uniprot id: A0A6J1YQN9
uniprot id: A0A6J1YSG8
uniprot id: A0A6J1YSJ0
uniprot id: A0A6J1YTR5
uniprot id: A0A6J1YTT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

32536:KRT71
gene id: 32536:KRT71
uniprot id: A0A6J0A4W3
names: Similarity
messages: Belongs to the intermediate filament family.

32536:LOC106988062
gene id: 32536:LOC106988062
uniprot id: A0A6J1XTP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:SLCO4C1
gene id: 32536:SLCO4C1
uniprot id: A0A6J0A3G9
uniprot id: A0A6J1XKP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:NMD3
gene id: 32536:NMD3
uniprot id: A0A6J1ZIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

32536:AMOTL1
gene id: 32536:AMOTL1
uniprot id: A0A6J1XTF2
uniprot id: A0A6J1XTG2
uniprot id: A0A6J1XTQ5
uniprot id: A0A6J1XTR1
uniprot id: A0A6J1XTX0
uniprot id: A0A6J1XTY0
names: Similarity
messages: Belongs to the angiomotin family.

32536:ACSM3
gene id: 32536:ACSM3
uniprot id: A0A6I9ZMM7
uniprot id: A0A6J1Y1U9
uniprot id: A0A6J1Y237
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:GABARAPL2
gene id: 32536:GABARAPL2
uniprot id: A0A6J2AU40
names: Similarity
messages: Belongs to the ATG8 family.

32536:IP6K3
gene id: 32536:IP6K3
uniprot id: A0A6I9ZQU6
uniprot id: A0A6J1ZBV3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

32536:DNASE2B
gene id: 32536:DNASE2B
uniprot id: A0A6I9ZLW5
uniprot id: A0A6I9ZNI5
names: Similarity
messages: Belongs to the DNase II family.

32536:LOC106982016
gene id: 32536:LOC106982016
uniprot id: A0A6J1YXS3
names: Subcellular Location Annotation
messages: Membrane

32536:PTAFR
gene id: 32536:PTAFR
uniprot id: A0A6I9ZUA0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

32536:SPIC
gene id: 32536:SPIC
uniprot id: A0A6I9ZME7
uniprot id: A0A6J2AAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:LOC106976862
gene id: 32536:LOC106976862
uniprot id: A0A6I9ZWI3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:LOC106971474
gene id: 32536:LOC106971474
uniprot id: A0A6J1YI23
names: Similarity
messages: Belongs to the peptidase C1 family.

32536:LOC106981197
gene id: 32536:LOC106981197
uniprot id: A0A6J0A2E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

32536:CPLANE2
gene id: 32536:CPLANE2
uniprot id: A0A6I9ZRH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
messages: cilium basal body

32536:NDUFV1
gene id: 32536:NDUFV1
uniprot id: A0A6J1Y8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

32536:RARB
gene id: 32536:RARB
uniprot id: A0A6J1XVX9
uniprot id: A0A6J1XW93
uniprot id: A0A6J1XWC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:PRDX6
gene id: 32536:PRDX6
uniprot id: A0A6I9ZXP8
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

32536:HOXA5
gene id: 32536:HOXA5
uniprot id: A0A6J2ALV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:GINS2
gene id: 32536:GINS2
uniprot id: A0A6J2AQ53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus

32536:PML
gene id: 32536:PML
uniprot id: A0A6I9ZX11
uniprot id: A0A6J2A155
uniprot id: A0A6J2A161
uniprot id: A0A6J2A269
uniprot id: A0A6J2A273
names: Subcellular Location Annotation
messages: Cytoplasm

32536:LOC113597382
gene id: 32536:LOC113597382
uniprot id: A0A6J1YV05
names: Similarity
messages: Belongs to the histone H3 family.

32536:GATA2
gene id: 32536:GATA2
uniprot id: A0A6J1YLH0
names: Subcellular Location Annotation
messages: Nucleus

32536:CHD9
gene id: 32536:CHD9
uniprot id: A0A6J1Y5E2
uniprot id: A0A6J1Y645
uniprot id: A0A6J1Y653
uniprot id: A0A6J1Y6C5
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

32536:LOC106989785
gene id: 32536:LOC106989785
uniprot id: A0A6J0ABH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PNPO
gene id: 32536:PNPO
uniprot id: A0A6I9ZYF1
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

32536:GNPNAT1
gene id: 32536:GNPNAT1
uniprot id: A0A6J0A3K1
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

32536:ATP5F1C
gene id: 32536:ATP5F1C
uniprot id: A0A6I9ZYP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

32536:SORD
gene id: 32536:SORD
uniprot id: A0A6I9ZF29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Homotetramer.
messages: Mitochondrion membrane
messages: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility.
messages: flagellum

32536:PXMP4
gene id: 32536:PXMP4
uniprot id: A0A6J2ABC9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

32536:NKX2-4
gene id: 32536:NKX2-4
uniprot id: A0A6J2A6W5
names: Subcellular Location Annotation
messages: Nucleus

32536:KCNF1
gene id: 32536:KCNF1
uniprot id: A0A6I9ZXG0
names: Subcellular Location Annotation
messages: Membrane

32536:TPH2
gene id: 32536:TPH2
uniprot id: A0A6I9ZIA5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

32536:ADSS1
gene id: 32536:ADSS1
uniprot id: A0A6J1ZYA1
uniprot id: A0A6J1ZZF9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

32536:RPS9
gene id: 32536:RPS9
uniprot id: A0A6J0A1D2
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

32536:DEFB123
gene id: 32536:DEFB123
uniprot id: A0A6J0A782
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

32536:RBP7
gene id: 32536:RBP7
uniprot id: A0A6J1ZFZ4
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

32536:SLC2A13
gene id: 32536:SLC2A13
uniprot id: A0A6J0A5L5
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

32536:PLXND1
gene id: 32536:PLXND1
uniprot id: A0A6J1Y164
uniprot id: A0A6J1Y1H3
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SOX4
gene id: 32536:SOX4
uniprot id: A0A6J1XUE8
names: Subcellular Location Annotation
messages: Nucleus

32536:WDR18
gene id: 32536:WDR18
uniprot id: A0A6J1YL65
uniprot id: A0A6J1YM51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and SENP3; the complex interacts with methylated CHTOP and ZNF148. Interacts with NOL9. Component of the PELP1 complex, composed of at least PELP1, TEX10 and WDR18. The complex interacts with pre-60S ribosome particles.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit. May play a role during development.
messages: nucleolus
messages: nucleoplasm

32536:PFDN4
gene id: 32536:PFDN4
uniprot id: A0A6J1YCZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

32536:POMC
gene id: 32536:POMC
uniprot id: A0A6J1X9W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

32536:NRXN2
gene id: 32536:NRXN2
uniprot id: A0A6J1Y9G1
uniprot id: A0A6J1Y9J7
uniprot id: A0A6J1YA61
uniprot id: A0A6J1YAM2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ABCA13
gene id: 32536:ABCA13
uniprot id: A0A6J1YB29
names: Subcellular Location Annotation
messages: Membrane

32536:HBS1L
gene id: 32536:HBS1L
uniprot id: A0A6J0A1V9
uniprot id: A0A6J0A215
names: Subcellular Location Annotation
messages: Cytoplasm

32536:ATRN
gene id: 32536:ATRN
uniprot id: A0A6J2A6J4
uniprot id: A0A6J2A7D0
uniprot id: A0A6J2AA98
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106983423
gene id: 32536:LOC106983423
uniprot id: A0A6J2AUL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

32536:NDUFA6
gene id: 32536:NDUFA6
uniprot id: A0A6J2A996
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

32536:GJA3
gene id: 32536:GJA3
uniprot id: A0A6J1ZSA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

32536:PHKB
gene id: 32536:PHKB
uniprot id: A0A6J1Y5T7
uniprot id: A0A6J1Y6D9
uniprot id: A0A6J1Y6K9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

32536:TIPARP
gene id: 32536:TIPARP
uniprot id: A0A6I9ZJG4
names: Similarity
messages: Belongs to the ARTD/PARP family.

32536:GPN1
gene id: 32536:GPN1
uniprot id: A0A6I9ZHC6
uniprot id: A0A6I9ZJ04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

32536:LOC106977941
gene id: 32536:LOC106977941
uniprot id: A0A6I9ZTF3
uniprot id: A0A6I9ZX28
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TNFAIP1
gene id: 32536:TNFAIP1
uniprot id: A0A6J1XCT6
names: Similarity
messages: Belongs to the BACURD family.

32536:RAB27B
gene id: 32536:RAB27B
uniprot id: A0A6J2A4R1
uniprot id: A0A6J2A8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

32536:GPRC5B
gene id: 32536:GPRC5B
uniprot id: A0A6J1Y280
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:FAM171A1
gene id: 32536:FAM171A1
uniprot id: A0A6J2AIS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

32536:MRPL23
gene id: 32536:MRPL23
uniprot id: A0A6J1YA58
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

32536:NR4A1
gene id: 32536:NR4A1
uniprot id: A0A6J1XHP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR4 subfamily.
messages: In the cytosol, upon its detection of both bacterial lipopolysaccharide (LPS) and NBRE-containing mitochondrial DNA released by GSDMD pores during pyroptosis, it promotes non-canonical NLRP3 inflammasome activation by stimulating association of NLRP3 and NEK7.
messages: Nucleus
messages: cytosol

32536:RPL13
gene id: 32536:RPL13
uniprot id: A0A6J2AQW7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

32536:APOC1
gene id: 32536:APOC1
uniprot id: P0DP51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
messages: Secreted

32536:ANAPC4
gene id: 32536:ANAPC4
uniprot id: A0A6J1YI43
uniprot id: A0A6J1YKL5
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

32536:KCNK5
gene id: 32536:KCNK5
uniprot id: A0A6I9ZQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:HEATR5A
gene id: 32536:HEATR5A
uniprot id: A0A6J1ZUT7
uniprot id: A0A6J1ZVB9
uniprot id: A0A6J1ZW37
uniprot id: A0A6J1ZXL4
uniprot id: A0A6J1ZXM0
names: Similarity
messages: Belongs to the HEATR5 family.

32536:LOC106966122
gene id: 32536:LOC106966122
uniprot id: A0A6I9ZBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TUSC3
gene id: 32536:TUSC3
uniprot id: A0A6J2ASS1
uniprot id: A0A6J2AT57
uniprot id: A0A6J2AX50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:PRKCD
gene id: 32536:PRKCD
uniprot id: A0A6J1XQF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

32536:TMEM192
gene id: 32536:TMEM192
uniprot id: A0A6J2A7D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

32536:SSR3
gene id: 32536:SSR3
uniprot id: A0A6I9ZI26
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

32536:ITPKB
gene id: 32536:ITPKB
uniprot id: A0A6J1YAW9
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

32536:RPS4X
gene id: 32536:RPS4X
uniprot id: A0A6J0A3J7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

32536:MTCH1
gene id: 32536:MTCH1
uniprot id: A0A6I9ZPD5
uniprot id: A0A6J1ZA66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:SYS1
gene id: 32536:SYS1
uniprot id: A0A6J2A818
uniprot id: A0A6J2A841
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

32536:PDCD4
gene id: 32536:PDCD4
uniprot id: A0A6J0A327
uniprot id: A0A6J1ZMW0
uniprot id: A0A6J1ZP09
names: Similarity
messages: Belongs to the PDCD4 family.

32536:NRXN3
gene id: 32536:NRXN3
uniprot id: A0A6J1ZX28
uniprot id: A0A6J1ZX32
uniprot id: A0A6J1ZXD7
uniprot id: A0A6J1ZXE6
uniprot id: A0A6J1ZXF7
uniprot id: A0A6J1ZXG1
uniprot id: A0A6J1ZYA4
uniprot id: A0A6J1ZYA8
uniprot id: A0A6J1ZZV9
uniprot id: A0A6J1ZZX3
uniprot id: A0A6J1ZZX9
uniprot id: A0A6J2A133
uniprot id: A0A6J2A142
uniprot id: A0A6J2A148
uniprot id: A0A6J2A158
uniprot id: A0A6J2A162
uniprot id: A0A6J2A167
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Presynaptic cell membrane

32536:ADAMTS3
gene id: 32536:ADAMTS3
uniprot id: A0A6J1ZA72
uniprot id: A0A6J1ZB31
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:IP6K2
gene id: 32536:IP6K2
uniprot id: A0A6I9ZVJ8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

32536:BARX2
gene id: 32536:BARX2
uniprot id: A0A6I9ZNE6
names: Subcellular Location Annotation
messages: Nucleus

32536:CFAP418
gene id: 32536:CFAP418
uniprot id: A0A6J0A5C2
uniprot id: A0A6J1ZTR4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

32536:CXCL13
gene id: 32536:CXCL13
uniprot id: A0A6I9ZWK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

32536:LOC106976323
gene id: 32536:LOC106976323
uniprot id: A0A6I9ZSH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PIK3C2G
gene id: 32536:PIK3C2G
uniprot id: A0A6I9ZSD4
uniprot id: A0A6J1XG43
uniprot id: A0A6J1XG62
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:DYM
gene id: 32536:DYM
uniprot id: A0A6I9ZP25
uniprot id: A0A6J2A4K2
uniprot id: A0A6J2A5M1
names: Similarity
messages: Belongs to the dymeclin family.

32536:DOCK8
gene id: 32536:DOCK8
uniprot id: A0A6J1XWC6
uniprot id: A0A6J1XWQ9
uniprot id: A0A6J1XWR4
uniprot id: A0A6J1XWR5
uniprot id: A0A6J1XX75
names: Similarity
messages: Belongs to the DOCK family.

32536:PTPRK
gene id: 32536:PTPRK
uniprot id: A0A6J1Z5H1
uniprot id: A0A6J1Z5Y8
uniprot id: A0A6J1Z6T5
uniprot id: A0A6J1Z8V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

32536:IL26
gene id: 32536:IL26
uniprot id: A0A6I9ZF09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

32536:INPP4A
gene id: 32536:INPP4A
uniprot id: A0A6J2AEP9
uniprot id: A0A6J2AEQ4
uniprot id: A0A6J2AEQ8
uniprot id: A0A6J2AG56
uniprot id: A0A6J2AIQ7
uniprot id: A0A6J2AIS0
uniprot id: A0A6J2AJ33
uniprot id: A0A6J2AJ39
uniprot id: A0A6J2AJ43
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

32536:MMAB
gene id: 32536:MMAB
uniprot id: A0A6J1Y4F0
uniprot id: A0A6J1Y4K4
uniprot id: A0A6J1Y698
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

32536:ART4
gene id: 32536:ART4
uniprot id: A0A6I9ZE06
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

32536:PROS1
gene id: 32536:PROS1
uniprot id: A0A6J2AYU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:HOXD9
gene id: 32536:HOXD9
uniprot id: A0A6J1Z386
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

32536:HEXA
gene id: 32536:HEXA
uniprot id: A0A6I9ZPP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

32536:SYN1
gene id: 32536:SYN1
uniprot id: A0A6J1YX83
uniprot id: A0A6J1Z0G0
names: Similarity
messages: Belongs to the synapsin family.

32536:LOC113593971
gene id: 32536:LOC113593971
uniprot id: A0A6J1XU00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:SELENOM
gene id: 32536:SELENOM
uniprot id: A0A6J1YRE1
names: Similarity
messages: Belongs to the selenoprotein M/F family.

32536:CERT1
gene id: 32536:CERT1
uniprot id: A0A6J1XT19
uniprot id: A0A6J1XT99
uniprot id: A0A6J1XTH3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Golgi apparatus

32536:SLC12A2
gene id: 32536:SLC12A2
uniprot id: A0A6I9ZLH9
uniprot id: A0A6J2ART0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

32536:PDS5A
gene id: 32536:PDS5A
uniprot id: A0A6J1Z343
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

32536:LOC106983596
gene id: 32536:LOC106983596
uniprot id: A0A6J1YL46
uniprot id: A0A6J1YLN8
uniprot id: A0A6J1YMM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

32536:CRMP1
gene id: 32536:CRMP1
uniprot id: A0A6J2AWM2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

32536:MLH3
gene id: 32536:MLH3
uniprot id: A0A6I9ZT08
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

32536:IL17RA
gene id: 32536:IL17RA
uniprot id: A0A6J2AME8
uniprot id: A0A6J2AMS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:FERMT1
gene id: 32536:FERMT1
uniprot id: A0A6I9ZUS2
uniprot id: A0A6J2A6E4
names: Similarity
messages: Belongs to the kindlin family.

32536:TOR1A
gene id: 32536:TOR1A
uniprot id: A0A6J1XFC9
uniprot id: A0A6J1XFE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

32536:CACNG7
gene id: 32536:CACNG7
uniprot id: A0A6J1XL41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2.

32536:AK1
gene id: 32536:AK1
uniprot id: A0A6J1XEV5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.

32536:CACNA2D2
gene id: 32536:CACNA2D2
uniprot id: A0A6J1XPZ0
uniprot id: A0A6J1XQ64
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

32536:ATP11C
gene id: 32536:ATP11C
uniprot id: A0A6J1YZF2
uniprot id: A0A6J1YZF5
uniprot id: A0A6J1Z0K2
uniprot id: A0A6J1Z0K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

32536:TRARG1
gene id: 32536:TRARG1
uniprot id: A0A6I9ZFJ4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

32536:ITPRIP
gene id: 32536:ITPRIP
uniprot id: A0A6J1ZMT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

32536:GPX2
gene id: 32536:GPX2
uniprot id: A0A6I9ZKT0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

32536:TBPL2
gene id: 32536:TBPL2
uniprot id: A0A6J0A5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

32536:LOC106974665
gene id: 32536:LOC106974665
uniprot id: A0A6I9ZNN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SEMA3B
gene id: 32536:SEMA3B
uniprot id: A0A6I9ZZ32
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:FDXR
gene id: 32536:FDXR
uniprot id: A0A6J1YT92
uniprot id: A0A6J1YTA1
uniprot id: A0A6J1YV65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion
messages: Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.

32536:CPS1
gene id: 32536:CPS1
uniprot id: A0A6J1YTW3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:VPS41
gene id: 32536:VPS41
uniprot id: A0A6I9ZPW4
uniprot id: A0A6I9ZPX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

32536:AFG3L2
gene id: 32536:AFG3L2
uniprot id: A0A6J2A394
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

32536:GMPPA
gene id: 32536:GMPPA
uniprot id: A0A6J1YN60
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

32536:U2AF2
gene id: 32536:U2AF2
uniprot id: A0A6J1XKU3
uniprot id: A0A6J1XKU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Necessary for the splicing of pre-mRNA.
messages: Nucleus

32536:GPSM1
gene id: 32536:GPSM1
uniprot id: A0A6J1YQT5
names: Similarity
messages: Belongs to the GPSM family.

32536:TSHB
gene id: 32536:TSHB
uniprot id: A0A6I9ZLA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

32536:ATAT1
gene id: 32536:ATAT1
uniprot id: A0A6I9ZCC6
uniprot id: A0A6I9ZDQ8
uniprot id: A0A6I9ZFB2
uniprot id: A0A6I9ZGV6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

32536:LOC106985630
gene id: 32536:LOC106985630
uniprot id: A0A6J2AUU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:TOM1
gene id: 32536:TOM1
uniprot id: A0A6J2AA38
uniprot id: A0A6J2ADS6
uniprot id: A0A6J2AE69
names: Similarity
messages: Belongs to the TOM1 family.

32536:CLUH
gene id: 32536:CLUH
uniprot id: A0A6J1XDD0
uniprot id: A0A6J1XDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

32536:LOC106977908
gene id: 32536:LOC106977908
uniprot id: A0A6I9ZUR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106988040
gene id: 32536:LOC106988040
uniprot id: A0A6J1XU00
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:AIG1
gene id: 32536:AIG1
uniprot id: A0A6I9ZBA5
uniprot id: A0A6I9ZCR5
uniprot id: A0A6I9ZE83
uniprot id: A0A6I9ZFV2
uniprot id: A0A6J1Z4X8
uniprot id: A0A6J1Z4Y2
uniprot id: A0A6J1Z4Y6
uniprot id: A0A6J1Z580
uniprot id: A0A6J1Z692
uniprot id: A0A6J1Z697
uniprot id: A0A6J1Z6A1
uniprot id: A0A6J1Z6V8
uniprot id: A0A6J1Z6W3
uniprot id: A0A6J1Z897
uniprot id: A0A6J1Z8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

32536:USP14
gene id: 32536:USP14
uniprot id: A0A6I9ZM99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C19 family. USP14/UBP6 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS.

32536:APCS
gene id: 32536:APCS
uniprot id: A0A6J1YI74
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:SIX5
gene id: 32536:SIX5
uniprot id: A0A6J1XM76
names: Subcellular Location Annotation
messages: Nucleus

32536:NT5DC2
gene id: 32536:NT5DC2
uniprot id: A0A6J1XQA3
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

32536:GMPR
gene id: 32536:GMPR
uniprot id: A0A6J1XUR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.

32536:BDKRB2
gene id: 32536:BDKRB2
uniprot id: A0A6I9ZNN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

32536:SCUBE2
gene id: 32536:SCUBE2
uniprot id: A0A6J0A8Q2
uniprot id: A0A6J2AGB2
uniprot id: A0A6J2AGS2
uniprot id: A0A6J2AKB6
uniprot id: A0A6J2AKS9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:PURA
gene id: 32536:PURA
uniprot id: A0A6J2AVM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

32536:MEGF11
gene id: 32536:MEGF11
uniprot id: A0A6J2A1R3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:STX11
gene id: 32536:STX11
uniprot id: A0A6J1Z673
uniprot id: A0A6J1Z871
names: Similarity
messages: Belongs to the syntaxin family.

32536:CFAP300
gene id: 32536:CFAP300
uniprot id: A0A6J1YUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

32536:RAB33B
gene id: 32536:RAB33B
uniprot id: A0A6J1ZX59
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

32536:ACTA1
gene id: 32536:ACTA1
uniprot id: A0A6J1YDW3
names: Similarity
messages: Belongs to the actin family.

32536:RAMAC
gene id: 32536:RAMAC
uniprot id: A0A6J2A2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAM family.
messages: Nucleus

32536:EIF1B
gene id: 32536:EIF1B
uniprot id: A0A6J1XVF7
names: Similarity
messages: Belongs to the SUI1 family.

32536:NXPH4
gene id: 32536:NXPH4
uniprot id: A0A6I9ZRT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

32536:LHX1
gene id: 32536:LHX1
uniprot id: A0A6J1XCA2
names: Subcellular Location Annotation
messages: Nucleus

32536:PKD2L2
gene id: 32536:PKD2L2
uniprot id: A0A6I9ZER9
uniprot id: A0A6J2AVV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Membrane

32536:RHAG
gene id: 32536:RHAG
uniprot id: A0A6I9ZMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

32536:FMC1
gene id: 32536:FMC1
uniprot id: A0A6I9ZKY0
names: Similarity
messages: Belongs to the FMC1 family.

32536:DYNLT2B
gene id: 32536:DYNLT2B
uniprot id: A0A6J0AA52
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

32536:SLC39A5
gene id: 32536:SLC39A5
uniprot id: A0A6J2AFY2
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106967512
gene id: 32536:LOC106967512
uniprot id: A0A6J1ZYH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106970530
gene id: 32536:LOC106970530
uniprot id: A0A6I9ZI37
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:GABBR2
gene id: 32536:GABBR2
uniprot id: A0A6J1XS84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

32536:SPPL2B
gene id: 32536:SPPL2B
uniprot id: A0A6J1YJW5
uniprot id: A0A6J1YJW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

32536:MRPS15
gene id: 32536:MRPS15
uniprot id: A0A6I9ZND8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

32536:KDM1A
gene id: 32536:KDM1A
uniprot id: A0A6J1ZEP5
uniprot id: A0A6J1ZGZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

32536:DLGAP5
gene id: 32536:DLGAP5
uniprot id: A0A6J0A6G1
uniprot id: A0A6J1ZWP8
uniprot id: A0A6J1ZZM0
names: Similarity
messages: Belongs to the SAPAP family.

32536:SAXO1
gene id: 32536:SAXO1
uniprot id: A0A6I9ZGY4
names: Similarity
messages: Belongs to the FAM154 family.

32536:ZC3H12A
gene id: 32536:ZC3H12A
uniprot id: A0A6J1ZDR0
names: Similarity
messages: Belongs to the ZC3H12 family.

32536:RHBDD2
gene id: 32536:RHBDD2
uniprot id: A0A6J0A149
names: Subcellular Location Annotation
messages: Membrane

32536:GASK1A
gene id: 32536:GASK1A
uniprot id: A0A6I9ZCJ2
names: Similarity
messages: Belongs to the GASK family.

32536:SAR1A
gene id: 32536:SAR1A
uniprot id: A0A6J1ZKS5
names: Similarity
messages: Belongs to the small GTPase superfamily. SAR1 family.

32536:SPAM1
gene id: 32536:SPAM1
uniprot id: A0A6I9ZL89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

32536:EIF5A
gene id: 32536:EIF5A
uniprot id: A0A6J1YEY0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

32536:CAND1
gene id: 32536:CAND1
uniprot id: A0A6I9ZDG1
uniprot id: A0A6I9ZGI6
names: Similarity
messages: Belongs to the CAND family.

32536:FOXO3
gene id: 32536:FOXO3
uniprot id: A0A6J1Z843
names: Subcellular Location Annotation
messages: Nucleus

32536:POGLUT2
gene id: 32536:POGLUT2
uniprot id: A0A6J1ZTW2
uniprot id: A0A6J1ZV17
names: Similarity
messages: Belongs to the KDELC family.

32536:DMRT2
gene id: 32536:DMRT2
uniprot id: A0A6J1XWS1
uniprot id: A0A6J1XWS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

32536:TOB2
gene id: 32536:TOB2
uniprot id: A0A6J2A9C4
names: Similarity
messages: Belongs to the BTG family.

32536:RDX
gene id: 32536:RDX
uniprot id: A0A6J1XIF1
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

32536:LOC106974091
gene id: 32536:LOC106974091
uniprot id: A0A6J1Z018
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

32536:CFL2
gene id: 32536:CFL2
uniprot id: A0A6J1ZXP9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

32536:SMG8
gene id: 32536:SMG8
uniprot id: A0A6J0ABM8
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

32536:MRPS11
gene id: 32536:MRPS11
uniprot id: A0A6J2A608
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

32536:LOC106978634
gene id: 32536:LOC106978634
uniprot id: A0A6I9ZY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106986889
gene id: 32536:LOC106986889
uniprot id: A0A6J0A999
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PDIA4
gene id: 32536:PDIA4
uniprot id: A0A6J2ANE8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Part of a large chaperone multiprotein complex.

32536:PMEL
gene id: 32536:PMEL
uniprot id: A0A6J0A8I1
names: Similarity
messages: Belongs to the PMEL/NMB family.

32536:LOC106968514
gene id: 32536:LOC106968514
uniprot id: A0A6J2A1Z8
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

32536:HHEX
gene id: 32536:HHEX
uniprot id: A0A6J1ZMV4
names: Subcellular Location Annotation
messages: Nucleus

32536:ATE1
gene id: 32536:ATE1
uniprot id: A0A6J1ZR21
uniprot id: A0A6J1ZSB7
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

32536:LOC106977307
gene id: 32536:LOC106977307
uniprot id: A0A6I9ZU05
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

32536:OSBPL2
gene id: 32536:OSBPL2
uniprot id: A0A6J1YC54
uniprot id: A0A6J1YDF8
names: Similarity
messages: Belongs to the OSBP family.

32536:GUCY2D
gene id: 32536:GUCY2D
uniprot id: A0A6J1YFN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

32536:ADD1
gene id: 32536:ADD1
uniprot id: A0A6J2A587
uniprot id: A0A6J2A6D9
uniprot id: A0A6J2A796
uniprot id: A0A6J2A903
uniprot id: A0A6J2A964
uniprot id: A0A6J2A9S2
uniprot id: A0A6J2AA50
uniprot id: A0A6J2AAB3
uniprot id: A0A6J2AAG9
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

32536:TAAR2
gene id: 32536:TAAR2
uniprot id: A0A6I9ZRV9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:SLC37A1
gene id: 32536:SLC37A1
uniprot id: A0A6J1XXL4
uniprot id: A0A6J1XXM2
uniprot id: A0A6J1XXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

32536:SIDT1
gene id: 32536:SIDT1
uniprot id: A0A6I9ZXP9
uniprot id: A0A6J1ZHW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

32536:MRPS16
gene id: 32536:MRPS16
uniprot id: A0A6I9ZKD9
uniprot id: A0A6J1ZPB9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

32536:YAE1
gene id: 32536:YAE1
uniprot id: A0A6I9ZRP6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:ADRA1B
gene id: 32536:ADRA1B
uniprot id: A0A6J1XA37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

32536:RIMKLB
gene id: 32536:RIMKLB
uniprot id: A0A6J2AJM9
names: Similarity
messages: Belongs to the RimK family.

32536:BZW2
gene id: 32536:BZW2
uniprot id: A0A6J0A2K3
names: Similarity
messages: Belongs to the BZW family.

32536:LOC106974767
gene id: 32536:LOC106974767
uniprot id: A0A6I9ZSA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MED11
gene id: 32536:MED11
uniprot id: A0A6J1YEW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:VARS1
gene id: 32536:VARS1
uniprot id: A0A6J1ZAW1
uniprot id: A0A6J1ZC67
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:LOC106987563
gene id: 32536:LOC106987563
uniprot id: A0A6J0A967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:SGCD
gene id: 32536:SGCD
uniprot id: A0A6J2AUG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

32536:HOXB7
gene id: 32536:HOXB7
uniprot id: A0A6J1XBE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:DVL1
gene id: 32536:DVL1
uniprot id: A0A6J1ZGD8
uniprot id: A0A6J1ZGP4
uniprot id: A0A6J1ZJU8
names: Similarity
messages: Belongs to the DSH family.

32536:SLC25A15
gene id: 32536:SLC25A15
uniprot id: A0A6I9ZML3
uniprot id: A0A6J1ZVA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:LOC106989578
gene id: 32536:LOC106989578
uniprot id: A0A6J1YUE7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

32536:ALDH1A3
gene id: 32536:ALDH1A3
uniprot id: A0A6J2A2R4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:TPD52L1
gene id: 32536:TPD52L1
uniprot id: A0A6J0A4H9
uniprot id: A0A6J0A4I7
uniprot id: A0A6J0A736
uniprot id: A0A6J0A7F2
uniprot id: A0A6J0A878
uniprot id: A0A6J1Z622
names: Similarity
messages: Belongs to the TPD52 family.

32536:EFEMP2
gene id: 32536:EFEMP2
uniprot id: A0A6J1Y9G5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106976617
gene id: 32536:LOC106976617
uniprot id: A0A6I9ZW40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TCTN3
gene id: 32536:TCTN3
uniprot id: A0A6J0A336
uniprot id: A0A6J0A345
uniprot id: A0A6J0A5U0
uniprot id: A0A6J0A6X0
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

32536:GABRB1
gene id: 32536:GABRB1
uniprot id: A0A6J1Z546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:LOC106986031
gene id: 32536:LOC106986031
uniprot id: A0A6J1YBV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

32536:CLK4
gene id: 32536:CLK4
uniprot id: A0A6J2AWR9
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:GLP2R
gene id: 32536:GLP2R
uniprot id: A0A6J1YE21
names: Subcellular Location Annotation
messages: Membrane

32536:SEM1
gene id: 32536:SEM1
uniprot id: A0A6J2ACS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

32536:LOC106978622
gene id: 32536:LOC106978622
uniprot id: A0A6I9ZVW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106966009
gene id: 32536:LOC106966009
uniprot id: A0A6I9ZEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PDP1
gene id: 32536:PDP1
uniprot id: A0A6J1ZRI7
uniprot id: A0A6J1ZSB4
names: Similarity
messages: Belongs to the PP2C family.

32536:HSD17B7
gene id: 32536:HSD17B7
uniprot id: A0A6J2AN92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

32536:FOXR1
gene id: 32536:FOXR1
uniprot id: A0A6J1XJ18
names: Subcellular Location Annotation
messages: Nucleus

32536:EIF4A1
gene id: 32536:EIF4A1
uniprot id: A0A6J1YF12
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:MAP4K3
gene id: 32536:MAP4K3
uniprot id: A0A6J1XAA2
uniprot id: A0A6J1XAA5
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

32536:CTPS1
gene id: 32536:CTPS1
uniprot id: A0A6J1ZDF3
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

32536:MRPS14
gene id: 32536:MRPS14
uniprot id: A0A6I9ZJJ7
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

32536:ARL2BP
gene id: 32536:ARL2BP
uniprot id: A0A6I9ZX59
uniprot id: A0A6J2AQM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

32536:NCEH1
gene id: 32536:NCEH1
uniprot id: A0A6J0A9A4
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

32536:IFRD2
gene id: 32536:IFRD2
uniprot id: A0A6I9ZZY2
uniprot id: A0A6J1XPY2
names: Similarity
messages: Belongs to the IFRD family.

32536:EMP2
gene id: 32536:EMP2
uniprot id: A0A6J1Y453
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

32536:LOC106972467
gene id: 32536:LOC106972467
uniprot id: A0A6I9ZQF2
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

32536:GPX8
gene id: 32536:GPX8
uniprot id: A0A6J0A8T7
names: Similarity
messages: Belongs to the glutathione peroxidase family.

32536:SLC44A5
gene id: 32536:SLC44A5
uniprot id: A0A6J1ZBL4
uniprot id: A0A6J1ZBL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

32536:EIF3E
gene id: 32536:EIF3E
uniprot id: A0A6I9ZNK6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

32536:PLD3
gene id: 32536:PLD3
uniprot id: A0A6J1Y842
names: Similarity
messages: Belongs to the phospholipase D family.

32536:CMTM6
gene id: 32536:CMTM6
uniprot id: A0A6J1XVN7
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106979443
gene id: 32536:LOC106979443
uniprot id: A0A6I9ZX15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

32536:CE4H1orf74
gene id: 32536:CE4H1orf74
uniprot id: A0A6J0A314
names: Similarity
messages: Belongs to the UPF0739 family.

32536:ATP5MC1
gene id: 32536:ATP5MC1
uniprot id: A0A6J0A0Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

32536:DPH3
gene id: 32536:DPH3
uniprot id: A0A6I9ZMT7
names: Similarity
messages: Belongs to the DPH3 family.

32536:S100A2
gene id: 32536:S100A2
uniprot id: A0A6J0A639
uniprot id: A0A6J0A8W7
names: Similarity
messages: Belongs to the S-100 family.

32536:KDM5C
gene id: 32536:KDM5C
uniprot id: A0A6J1YVT1
uniprot id: A0A6J1YVT6
uniprot id: A0A6J1YVY1
uniprot id: A0A6J1YVY7
uniprot id: A0A6J1YVZ8
uniprot id: A0A6J1YX92
uniprot id: A0A6J1YXT0
uniprot id: A0A6J1YXU1
uniprot id: A0A6J1YZ71
uniprot id: A0A6J1YZ76
uniprot id: A0A6J1YZ86
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

32536:PAF1
gene id: 32536:PAF1
uniprot id: A0A6I9ZZN1
names: Similarity
messages: Belongs to the PAF1 family.

32536:P2RY8
gene id: 32536:P2RY8
uniprot id: A0A6J1YVY4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:RPL12
gene id: 32536:RPL12
uniprot id: A0A6J1XES0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.

32536:AGL
gene id: 32536:AGL
uniprot id: A0A6J1ZB57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

32536:CWC15
gene id: 32536:CWC15
uniprot id: A0A6J0A8C6
names: Similarity
messages: Belongs to the CWC15 family.

32536:ST6GALNAC4
gene id: 32536:ST6GALNAC4
uniprot id: A0A6I9ZEY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:FOXA2
gene id: 32536:FOXA2
uniprot id: A0A6J2A9S8
uniprot id: A0A6J2AA69
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106982807
gene id: 32536:LOC106982807
uniprot id: A0A6J0A4J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:AMELX
gene id: 32536:AMELX
uniprot id: A0A6J1YZT9
names: Similarity
messages: Belongs to the amelogenin family.

32536:SFXN2
gene id: 32536:SFXN2
uniprot id: A0A6J1ZMN3
uniprot id: A0A6J1ZQ60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

32536:OCEL1
gene id: 32536:OCEL1
uniprot id: A0A6J1XNR3
names: Similarity
messages: Belongs to the ELL/occludin family.

32536:MTERF1
gene id: 32536:MTERF1
uniprot id: A0A6I9ZM47
uniprot id: A0A6J2AGH6
names: Similarity
messages: Belongs to the mTERF family.

32536:FAM83G
gene id: 32536:FAM83G
uniprot id: A0A6J0A233
names: Similarity
messages: Belongs to the FAM83 family.

32536:EPN3
gene id: 32536:EPN3
uniprot id: A0A6J1XBL4
uniprot id: A0A6J1XBM2
uniprot id: A0A6J1XBM6
names: Similarity
messages: Belongs to the epsin family.

32536:SRP68
gene id: 32536:SRP68
uniprot id: A0A6J1YW26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

32536:IGF1
gene id: 32536:IGF1
uniprot id: A0A6J2AA33
uniprot id: A0A6J2AAC9
uniprot id: A0A6J2ABA2
uniprot id: A0A6J2AEG0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Forms a ternary complex with IGFR1 and ITGAV:ITGB3. Forms a ternary complex with IGFR1 and ITGA6:ITGB4.
messages: Secreted

32536:NRF1
gene id: 32536:NRF1
uniprot id: A0A6J2AMQ7
uniprot id: A0A6J2AN44
uniprot id: A0A6J2APH3
uniprot id: A0A6J2ART1
uniprot id: A0A6J2AS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

32536:LGR4
gene id: 32536:LGR4
uniprot id: A0A6J2AFM8
names: Subcellular Location Annotation
messages: Membrane

32536:LIG4
gene id: 32536:LIG4
uniprot id: A0A6J1ZWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

32536:SUGCT
gene id: 32536:SUGCT
uniprot id: A0A6J2AC64
names: Similarity
messages: Belongs to the CoA-transferase III family.

32536:RTN2
gene id: 32536:RTN2
uniprot id: A0A6I9ZST8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106989774
gene id: 32536:LOC106989774
uniprot id: A0A6J1ZP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

32536:ETS1
gene id: 32536:ETS1
uniprot id: A0A6J1XJM6
uniprot id: A0A6J1XJP5
uniprot id: A0A6J1XJR7
uniprot id: A0A6J1XJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

32536:VAMP3
gene id: 32536:VAMP3
uniprot id: A0A6J1ZG48
uniprot id: A0A6J1ZJ78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

32536:CCN3
gene id: 32536:CCN3
uniprot id: A0A6J1ZQW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:GCDH
gene id: 32536:GCDH
uniprot id: A0A6J1YNV5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

32536:CFAP36
gene id: 32536:CFAP36
uniprot id: A0A6I9ZT91
uniprot id: A0A6I9ZWT7
uniprot id: A0A6J2AFK4
names: Similarity
messages: Belongs to the CFAP36 family.

32536:SLC7A13
gene id: 32536:SLC7A13
uniprot id: A0A6I9ZSG1
names: Subcellular Location Annotation
messages: Membrane

32536:CDC14B
gene id: 32536:CDC14B
uniprot id: A0A6I9ZJG2
uniprot id: A0A6I9ZMJ7
uniprot id: A0A6J1YG67
uniprot id: A0A6J1YGZ1
uniprot id: A0A6J1YIA0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

32536:EDN1
gene id: 32536:EDN1
uniprot id: A0A6I9ZTJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

32536:TMEM135
gene id: 32536:TMEM135
uniprot id: A0A6I9ZE67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane

32536:GLIPR1
gene id: 32536:GLIPR1
uniprot id: A0A6J2AB30
names: Similarity
messages: Belongs to the CRISP family.

32536:NR2E1
gene id: 32536:NR2E1
uniprot id: A0A6J1Z628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:POLR1C
gene id: 32536:POLR1C
uniprot id: A0A6I9ZMW4
uniprot id: A0A6J1Z8B6
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

32536:PTPRM
gene id: 32536:PTPRM
uniprot id: A0A6J2A4H4
uniprot id: A0A6J2A7I0
uniprot id: A0A6J2A7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Cell membrane
messages: Membrane

32536:GLRB
gene id: 32536:GLRB
uniprot id: A0A6J2A1N8
uniprot id: A0A6J2A2W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:MAP7
gene id: 32536:MAP7
uniprot id: A0A6J1Z535
uniprot id: A0A6J1Z541
uniprot id: A0A6J1Z5F9
uniprot id: A0A6J1Z5G3
uniprot id: A0A6J1Z5H0
uniprot id: A0A6J1Z8F8
names: Similarity
messages: Belongs to the MAP7 family.

32536:CNOT9
gene id: 32536:CNOT9
uniprot id: A0A6I9ZHE1
uniprot id: A0A6I9ZKA2
uniprot id: A0A6J1YQW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

32536:MTHFD1L
gene id: 32536:MTHFD1L
uniprot id: A0A6J1Z613
uniprot id: A0A6J1Z6L2
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

32536:PLA2G5
gene id: 32536:PLA2G5
uniprot id: A0A6J0A487
uniprot id: A0A6J1ZEY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

32536:PSEN1
gene id: 32536:PSEN1
uniprot id: A0A6I9ZTV3
uniprot id: A0A6J1ZWS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

32536:TOR2A
gene id: 32536:TOR2A
uniprot id: A0A6I9ZC14
uniprot id: A0A6J1XER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

32536:CREB5
gene id: 32536:CREB5
uniprot id: A0A6J0A6P5
uniprot id: A0A6J0A9E6
uniprot id: A0A6J2AMB2
uniprot id: A0A6J2AMB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

32536:RC3H2
gene id: 32536:RC3H2
uniprot id: A0A6J1XED1
uniprot id: A0A6J1XED2
uniprot id: A0A6J1XEE0
uniprot id: A0A6J1XEF2
names: Subcellular Location Annotation
messages: P-body

32536:THOP1
gene id: 32536:THOP1
uniprot id: A0A6J1YIS7
uniprot id: A0A6J1YJP7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

32536:LOC106966101
gene id: 32536:LOC106966101
uniprot id: A0A6I9ZG60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ABT1
gene id: 32536:ABT1
uniprot id: A0A6J1XU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

32536:MOXD1
gene id: 32536:MOXD1
uniprot id: A0A6J1Z8M9
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

32536:TAF9B
gene id: 32536:TAF9B
uniprot id: A0A6J1YWF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

32536:TMCC1
gene id: 32536:TMCC1
uniprot id: A0A6J1Y0Q6
uniprot id: A0A6J1Y1H9
names: Similarity
messages: Belongs to the TEX28 family.

32536:METTL3
gene id: 32536:METTL3
uniprot id: A0A6I9ZPR4
names: Similarity
messages: Belongs to the MT-A70-like family.

32536:ISL1
gene id: 32536:ISL1
uniprot id: A0A6J0A9B0
names: Subcellular Location Annotation
messages: Nucleus

32536:HOXC9
gene id: 32536:HOXC9
uniprot id: A0A6J1XI40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

32536:LOC106969428
gene id: 32536:LOC106969428
uniprot id: A0A6I9ZL27
uniprot id: A0A6I9ZLH5
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

32536:CACNB4
gene id: 32536:CACNB4
uniprot id: A0A6I9ZS42
uniprot id: A0A6I9ZVA7
uniprot id: A0A6J1Z268
uniprot id: A0A6J1Z5M5
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

32536:SLC4A10
gene id: 32536:SLC4A10
uniprot id: A0A6J1Z1U2
uniprot id: A0A6J1Z248
uniprot id: A0A6J1Z352
uniprot id: A0A6J1Z3V9
uniprot id: A0A6J1Z5A5
uniprot id: A0A6J1Z5B0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane

32536:NLK
gene id: 32536:NLK
uniprot id: A0A6J1XCR1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

32536:EMC9
gene id: 32536:EMC9
uniprot id: A0A6J1ZYS7
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

32536:CAPRIN1
gene id: 32536:CAPRIN1
uniprot id: A0A6J2AFY4
names: Similarity
messages: Belongs to the caprin family.

32536:GTF2A1
gene id: 32536:GTF2A1
uniprot id: A0A6J0A4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

32536:PALM
gene id: 32536:PALM
uniprot id: A0A6J1YJM2
uniprot id: A0A6J1YKM4
uniprot id: A0A6J1YL70
uniprot id: A0A6J1YM56
names: Similarity
messages: Belongs to the paralemmin family.

32536:SESN2
gene id: 32536:SESN2
uniprot id: A0A6J1ZF89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

32536:SLC7A11
gene id: 32536:SLC7A11
uniprot id: A0A6I9ZUD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

32536:DESI1
gene id: 32536:DESI1
uniprot id: A0A6J2A970
names: Similarity
messages: Belongs to the DeSI family.

32536:CERCAM
gene id: 32536:CERCAM
uniprot id: A0A6J1XF10
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

32536:ST3GAL6
gene id: 32536:ST3GAL6
uniprot id: A0A6J0A3S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:UBE2H
gene id: 32536:UBE2H
uniprot id: A0A6J2AN48
uniprot id: A0A6J2AS96
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:MAML3
gene id: 32536:MAML3
uniprot id: A0A6J1ZYG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

32536:ARTN
gene id: 32536:ARTN
uniprot id: A0A6J1ZCG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

32536:CDH3
gene id: 32536:CDH3
uniprot id: A0A6J2APE5
uniprot id: A0A6J2APV0
uniprot id: A0A6J2AU38
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:EYA2
gene id: 32536:EYA2
uniprot id: A0A6J2ACH1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

32536:YIF1B
gene id: 32536:YIF1B
uniprot id: A0A6I9ZX91
uniprot id: A0A6J1Y6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

32536:AWAT2
gene id: 32536:AWAT2
uniprot id: A0A6J0A0D5
uniprot id: A0A6J1YXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

32536:CB1H4orf47
gene id: 32536:CB1H4orf47
uniprot id: A0A6J2ASS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP96 family.
messages: centrosome

32536:NR1D2
gene id: 32536:NR1D2
uniprot id: A0A6J1XVZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:LOC113593208
gene id: 32536:LOC113593208
uniprot id: A0A6J1XJA1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:GK
gene id: 32536:GK
uniprot id: A0A6J1YZ73
uniprot id: A0A6J1YZ78
uniprot id: A0A6J1Z0D3
uniprot id: A0A6J1Z173
uniprot id: A0A6J1Z2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

32536:SLC25A32
gene id: 32536:SLC25A32
uniprot id: A0A6I9ZXX4
uniprot id: A0A6J0A0C2
uniprot id: A0A6J0A109
uniprot id: A0A6J0A191
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:EIF2A
gene id: 32536:EIF2A
uniprot id: A0A6I9ZR04
uniprot id: A0A6J1ZJ48
uniprot id: A0A6J1ZME4
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

32536:MARK2
gene id: 32536:MARK2
uniprot id: A0A6J1Y8Y1
uniprot id: A0A6J1Y8Y7
uniprot id: A0A6J1Y8Y9
uniprot id: A0A6J1Y9N7
uniprot id: A0A6J1YA31
uniprot id: A0A6J1YAT6
uniprot id: A0A6J1YAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

32536:LOC106969819
gene id: 32536:LOC106969819
uniprot id: A0A6I9ZLY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SCNN1G
gene id: 32536:SCNN1G
uniprot id: A0A6J1Y1M1
uniprot id: A0A6J1Y1Y2
uniprot id: A0A6J1Y3F5
names: Subcellular Location Annotation
messages: Membrane

32536:CXCL11
gene id: 32536:CXCL11
uniprot id: A0A6J1ZCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

32536:KCNK15
gene id: 32536:KCNK15
uniprot id: A0A6J2ABS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:TAX1BP3
gene id: 32536:TAX1BP3
uniprot id: A0A6J0A932
uniprot id: A0A6J1XDJ2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

32536:GPR12
gene id: 32536:GPR12
uniprot id: A0A6J1ZTC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:HOXC13
gene id: 32536:HOXC13
uniprot id: A0A6J1XHY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

32536:PAPOLB
gene id: 32536:PAPOLB
uniprot id: A0A6I9ZYV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

32536:RDH16
gene id: 32536:RDH16
uniprot id: A0A6I9ZRU0
uniprot id: A0A6J2ACM3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:PROKR2
gene id: 32536:PROKR2
uniprot id: A0A6I9ZX29
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:ZDHHC3
gene id: 32536:ZDHHC3
uniprot id: A0A6J1XPB9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:SF3A1
gene id: 32536:SF3A1
uniprot id: A0A6J0A564
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106970185
gene id: 32536:LOC106970185
uniprot id: A0A6I9ZM39
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RDH5
gene id: 32536:RDH5
uniprot id: A0A6J0A5P9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:XCL2
gene id: 32536:XCL2
uniprot id: A0A6I9ZGE0
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.

32536:API5
gene id: 32536:API5
uniprot id: A0A6I9ZTP9
uniprot id: A0A6I9ZXC1
names: Similarity
messages: Belongs to the API5 family.

32536:CSTPP1
gene id: 32536:CSTPP1
uniprot id: A0A6I9ZXA0
uniprot id: A0A6I9ZY87
uniprot id: A0A6I9ZYF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: cytoskeleton

32536:LOC106966125
gene id: 32536:LOC106966125
uniprot id: A0A6I9ZEP7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NAPA
gene id: 32536:NAPA
uniprot id: A0A6J1XMN6
uniprot id: A0A6J1XMR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

32536:CHST13
gene id: 32536:CHST13
uniprot id: A0A6J1YM39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:SNRK
gene id: 32536:SNRK
uniprot id: A0A6J1XV84
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.

32536:CLDN9
gene id: 32536:CLDN9
uniprot id: A0A6I9ZW28
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

32536:RRAGA
gene id: 32536:RRAGA
uniprot id: A0A6J1YD93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

32536:GRK1
gene id: 32536:GRK1
uniprot id: A0A6J0A5D1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

32536:EPDR1
gene id: 32536:EPDR1
uniprot id: A0A6J2AC90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ependymin family.
messages: Binds anionic lipids and gangliosides at acidic pH.
messages: Lysosome lumen

32536:MAP3K21
gene id: 32536:MAP3K21
uniprot id: A0A6J0A2U6
uniprot id: A0A6J0A377
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

32536:ACTC1
gene id: 32536:ACTC1
uniprot id: A0A6J2A2R3
names: Similarity
messages: Belongs to the actin family.

32536:MAST2
gene id: 32536:MAST2
uniprot id: A0A6J1ZC50
uniprot id: A0A6J1ZC57
uniprot id: A0A6J1ZCU2
uniprot id: A0A6J1ZCU4
uniprot id: A0A6J1ZDH1
uniprot id: A0A6J1ZDH6
uniprot id: A0A6J1ZEF1
uniprot id: A0A6J1ZEF6
uniprot id: A0A6J1ZFK1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

32536:SLF2
gene id: 32536:SLF2
uniprot id: A0A6I9ZCS9
uniprot id: A0A6I9ZFQ6
names: Similarity
messages: Belongs to the FAM178 family.

32536:RHO
gene id: 32536:RHO
uniprot id: A0A6I9ZWZ0
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Contains one covalently linked retinal chromophore.
messages: Membrane

32536:EPHB2
gene id: 32536:EPHB2
uniprot id: A0A6J1ZEP9
uniprot id: A0A6J1ZF17
uniprot id: A0A6J1ZFV1
uniprot id: A0A6J1ZH00
uniprot id: A0A6J1ZI08
names: Subcellular Location Annotation
messages: Membrane

32536:PRPSAP1
gene id: 32536:PRPSAP1
uniprot id: A0A6J1YW99
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

32536:B2M
gene id: 32536:B2M
uniprot id: A0A6I9ZGK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

32536:NUTF2
gene id: 32536:NUTF2
uniprot id: A0A6J2ATX7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

32536:KCNJ1
gene id: 32536:KCNJ1
uniprot id: A0A6J0A5T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

32536:SLC5A10
gene id: 32536:SLC5A10
uniprot id: A0A6J1YFC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

32536:MED21
gene id: 32536:MED21
uniprot id: A0A6I9ZFQ2
uniprot id: A0A6I9ZIH7
uniprot id: A0A6J1XGI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

32536:RIPPLY2
gene id: 32536:RIPPLY2
uniprot id: A0A6J1Z3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

32536:LOC106986611
gene id: 32536:LOC106986611
uniprot id: A0A6J0A8V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TM6SF1
gene id: 32536:TM6SF1
uniprot id: A0A6J2A2F1
uniprot id: A0A6J2A2G0
uniprot id: A0A6J2A2Q0
uniprot id: A0A6J2A3K8
uniprot id: A0A6J2A5U8
uniprot id: A0A6J2A5Y0
uniprot id: A0A6J2A6L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TM6SF family.
messages: Membrane

32536:MPZ
gene id: 32536:MPZ
uniprot id: A0A6J1YHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

32536:KCNQ4
gene id: 32536:KCNQ4
uniprot id: A0A6J1ZF35
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:DPY30
gene id: 32536:DPY30
uniprot id: A0A6I9ZJ27
names: Similarity
messages: Belongs to the dpy-30 family.

32536:SUCLG1
gene id: 32536:SUCLG1
uniprot id: A0A6I9ZYG2
uniprot id: A0A6I9ZYK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

32536:NIT1
gene id: 32536:NIT1
uniprot id: A0A6I9ZUI6
uniprot id: A0A6I9ZVS6
uniprot id: A0A6I9ZZ01
uniprot id: A0A6I9ZZ15
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

32536:AQP3
gene id: 32536:AQP3
uniprot id: A0A6J1XRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

32536:NEU2
gene id: 32536:NEU2
uniprot id: A0A6J1YE39
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

32536:LOC106982925
gene id: 32536:LOC106982925
uniprot id: A0A6J1YN84
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TNNT2
gene id: 32536:TNNT2
uniprot id: A0A6J2AKC0
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

32536:SOX1
gene id: 32536:SOX1
uniprot id: A0A6J1ZWP7
names: Subcellular Location Annotation
messages: Nucleus

32536:ARMCX1
gene id: 32536:ARMCX1
uniprot id: A0A6J1YY52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

32536:IRF3
gene id: 32536:IRF3
uniprot id: A0A6J1XN29
uniprot id: A0A6J1XNC5
names: Subcellular Location Annotation
messages: Nucleus

32536:ASPH
gene id: 32536:ASPH
uniprot id: A0A6I9ZMI2
uniprot id: A0A6J1Y1P1
uniprot id: A0A6J1Y1T2
uniprot id: A0A6J1Y341
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

32536:POSTN
gene id: 32536:POSTN
uniprot id: A0A6I9ZMI9
uniprot id: A0A6I9ZMJ4
uniprot id: A0A6I9ZP60
uniprot id: A0A6I9ZQQ9
uniprot id: A0A6I9ZQR1
uniprot id: A0A6I9ZS73
uniprot id: A0A6I9ZT16
names: Subcellular Location Annotation
messages: extracellular matrix

32536:TMPRSS2
gene id: 32536:TMPRSS2
uniprot id: A0A6J1XYP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:NDUFB10
gene id: 32536:NDUFB10
uniprot id: A0A6J0A0M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

32536:AUH
gene id: 32536:AUH
uniprot id: A0A6J1XWK7
uniprot id: A0A6J1XWL1
uniprot id: A0A6J1XWN2
uniprot id: A0A6J1XWZ2
uniprot id: A0A6J1XX08
uniprot id: A0A6J1XX11
uniprot id: A0A6J1XXI9
uniprot id: A0A6J1XXJ9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

32536:CRYBG1
gene id: 32536:CRYBG1
uniprot id: A0A6J1Z9J9
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:DERL2
gene id: 32536:DERL2
uniprot id: A0A6J1YE98
uniprot id: A0A6J1YF32
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:XYLB
gene id: 32536:XYLB
uniprot id: A0A6J1XV87
uniprot id: A0A6J1XVK6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

32536:SERPINE3
gene id: 32536:SERPINE3
uniprot id: A0A6J1ZVB4
names: Similarity
messages: Belongs to the serpin family.

32536:BAZ1B
gene id: 32536:BAZ1B
uniprot id: A0A6J1XZ97
names: Subcellular Location Annotation
messages: Nucleus

32536:ACTL7A
gene id: 32536:ACTL7A
uniprot id: A0A6I9ZT70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: cytoskeleton

32536:FSCN2
gene id: 32536:FSCN2
uniprot id: A0A6J1YT28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

32536:FBXO46
gene id: 32536:FBXO46
uniprot id: A0A6J1XMF4
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

32536:CALCB
gene id: 32536:CALCB
uniprot id: A0A6J0A783
uniprot id: A0A6J2AFZ5
uniprot id: A0A6J2AGF8
names: Similarity
messages: Belongs to the calcitonin family.

32536:PXN
gene id: 32536:PXN
uniprot id: A0A6J1Y489
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

32536:PNRC2
gene id: 32536:PNRC2
uniprot id: A0A6J1ZEY4
names: Subcellular Location Annotation
messages: Nucleus

32536:CCKAR
gene id: 32536:CCKAR
uniprot id: A0A6J1YS12
uniprot id: A0A6J1YSA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

32536:PPFIBP2
gene id: 32536:PPFIBP2
uniprot id: A0A6J0A4Y6
uniprot id: A0A6J0A7V8
uniprot id: A0A6J0A8P7
uniprot id: A0A6J2AGX2
uniprot id: A0A6J2AI07
uniprot id: A0A6J2AKI8
uniprot id: A0A6J2AKX0
uniprot id: A0A6J2AKX5
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.

32536:LOC106967211
gene id: 32536:LOC106967211
uniprot id: A0A6J1ZN21
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

32536:LOC106989736
gene id: 32536:LOC106989736
uniprot id: B0M1H2
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

32536:HSPD1
gene id: 32536:HSPD1
uniprot id: A0A6I9ZWX4
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

32536:NDRG2
gene id: 32536:NDRG2
uniprot id: A0A6I9ZNX0
uniprot id: A0A6J1ZX19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

32536:TET1
gene id: 32536:TET1
uniprot id: A0A6J1ZKP4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

32536:TMEM54
gene id: 32536:TMEM54
uniprot id: A0A6J1ZDQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM54 family.
messages: Membrane

32536:ACAD8
gene id: 32536:ACAD8
uniprot id: A0A6I9ZQY1
uniprot id: A0A6I9ZUQ5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

32536:STAT1
gene id: 32536:STAT1
uniprot id: A0A6J0A0I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

32536:PTOV1
gene id: 32536:PTOV1
uniprot id: A0A6J1XNG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activates transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.
messages: Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: May interact with CREBBP. Interacts with FLOT1.
messages: Nucleus
messages: perinuclear region

32536:LOC106974904
gene id: 32536:LOC106974904
uniprot id: A0A6I9ZTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:SLCO3A1
gene id: 32536:SLCO3A1
uniprot id: A0A6J2A1T5
uniprot id: A0A6J2A2Z3
uniprot id: A0A6J2A534
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

32536:OSBPL8
gene id: 32536:OSBPL8
uniprot id: A0A6J2AAQ5
uniprot id: A0A6J2AAQ9
uniprot id: A0A6J2AB16
uniprot id: A0A6J2ABY4
uniprot id: A0A6J2ABY9
uniprot id: A0A6J2AEN9
uniprot id: A0A6J2AF54
names: Similarity
messages: Belongs to the OSBP family.

32536:ITPA
gene id: 32536:ITPA
uniprot id: A0A6J0A153
uniprot id: A0A6J0A1D4
uniprot id: A0A6J2AAT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

32536:NPB
gene id: 32536:NPB
uniprot id: A0A6J1YUS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

32536:NPNT
gene id: 32536:NPNT
uniprot id: A0A6J1ZJM8
uniprot id: A0A6J1ZK10
uniprot id: A0A6J1ZKU4
uniprot id: A0A6J1ZM01
uniprot id: A0A6J1ZM06
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:NUP205
gene id: 32536:NUP205
uniprot id: A0A6I9ZRL9
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

32536:SMG7
gene id: 32536:SMG7
uniprot id: A0A6J2AJJ3
uniprot id: A0A6J2AJJ7
uniprot id: A0A6J2AK46
uniprot id: A0A6J2AL66
uniprot id: A0A6J2ANP5
uniprot id: A0A6J2ANQ0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

32536:MAP4K1
gene id: 32536:MAP4K1
uniprot id: A0A6J1Y7G8
uniprot id: A0A6J1Y7N8
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

32536:UBE2E2
gene id: 32536:UBE2E2
uniprot id: A0A6J1XW01
uniprot id: A0A6J1XWC0
uniprot id: A0A6J1XWU1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:PSMA7
gene id: 32536:PSMA7
uniprot id: A0A6J1YDH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

32536:KDM1B
gene id: 32536:KDM1B
uniprot id: A0A6J1XUR1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

32536:SOX12
gene id: 32536:SOX12
uniprot id: A0A6J2AAL8
names: Subcellular Location Annotation
messages: Nucleus

32536:NEK8
gene id: 32536:NEK8
uniprot id: A0A6J1XCV5
uniprot id: A0A6J1XCW0
uniprot id: A0A6J1XCX1
uniprot id: A0A6J1XCX9
uniprot id: A0A6J1XCY2
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

32536:LOC106968256
gene id: 32536:LOC106968256
uniprot id: A0A6J1Z0R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

32536:CTSO
gene id: 32536:CTSO
uniprot id: A0A6J0A0H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

32536:LMBR1
gene id: 32536:LMBR1
uniprot id: A0A6J1YPC9
uniprot id: A0A6J1YR57
names: Similarity
messages: Belongs to the LIMR family.

32536:LOC106966227
gene id: 32536:LOC106966227
uniprot id: A0A6I9ZEV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

32536:MINPP1
gene id: 32536:MINPP1
uniprot id: A0A6J1YMH9
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

32536:KCNQ2
gene id: 32536:KCNQ2
uniprot id: A0A6J1YBD0
uniprot id: A0A6J1YBD6
uniprot id: A0A6J1YC15
uniprot id: A0A6J1YC19
uniprot id: A0A6J1YCN3
uniprot id: A0A6J1YDB2
uniprot id: A0A6J1YDC4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:GAD2
gene id: 32536:GAD2
uniprot id: A0A6J0A6P1
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

32536:LOC106983074
gene id: 32536:LOC106983074
uniprot id: A0A6J0A100
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CACNA1S
gene id: 32536:CACNA1S
uniprot id: A0A6J2APH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

32536:RSPO2
gene id: 32536:RSPO2
uniprot id: A0A6J1ZUN1
names: Similarity
messages: Belongs to the R-spondin family.

32536:B4GALT4
gene id: 32536:B4GALT4
uniprot id: A0A6J1ZGT9
uniprot id: A0A6J1ZJ76
uniprot id: A0A6J1ZKA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

32536:LOC106987376
gene id: 32536:LOC106987376
uniprot id: A0A6J0A8X3
names: Similarity
messages: Belongs to the transferrin family.

32536:DCPS
gene id: 32536:DCPS
uniprot id: A0A6J1XJG8
uniprot id: A0A6J1XJK2
uniprot id: A0A6J1XJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HIT family.
messages: Cytoplasm
messages: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.
messages: Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.
messages: Nucleus

32536:LOC106986174
gene id: 32536:LOC106986174
uniprot id: A0A6J0A4K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:BAX
gene id: 32536:BAX
uniprot id: A0A6J1XMZ0
uniprot id: A0A6J1XN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

32536:GON4L
gene id: 32536:GON4L
uniprot id: A0A6J0A351
uniprot id: A0A6J1YGC5
names: Subcellular Location Annotation
messages: Nucleus

32536:INO80D
gene id: 32536:INO80D
uniprot id: A0A6J1YV03
names: Subcellular Location Annotation
messages: Nucleus

32536:NDUFA7
gene id: 32536:NDUFA7
uniprot id: A0A6J1YME9
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

32536:HOXC11
gene id: 32536:HOXC11
uniprot id: A0A6J1XI70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

32536:PRRX1
gene id: 32536:PRRX1
uniprot id: A0A6J1YAG6
uniprot id: A0A6J1YAH4
uniprot id: A0A6J1YBN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

32536:EFNB1
gene id: 32536:EFNB1
uniprot id: A0A6J1YZE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:TDGF1
gene id: 32536:TDGF1
uniprot id: A0A6I9ZGB2
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:MIOX
gene id: 32536:MIOX
uniprot id: A0A6J2A9G5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

32536:LOC106985135
gene id: 32536:LOC106985135
uniprot id: A0A6J0A3F1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106966133
gene id: 32536:LOC106966133
uniprot id: A0A6I9ZD60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PIERCE1
gene id: 32536:PIERCE1
uniprot id: A0A6J1YQQ2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

32536:NMT1
gene id: 32536:NMT1
uniprot id: A0A6J0A7C6
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

32536:METTL16
gene id: 32536:METTL16
uniprot id: A0A6J1XDA3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

32536:TFAP2B
gene id: 32536:TFAP2B
uniprot id: A0A6J0A372
uniprot id: A0A6J1Z795
uniprot id: A0A6J1Z8M5
uniprot id: A0A6J1Z9F6
names: Similarity
messages: Belongs to the AP-2 family.

32536:LOC106980612
gene id: 32536:LOC106980612
uniprot id: A0A6J1XVA6
names: Subcellular Location Annotation
messages: Nucleus

32536:GPR137C
gene id: 32536:GPR137C
uniprot id: A0A6J0A348
uniprot id: A0A6J1ZVD3
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

32536:LOXL3
gene id: 32536:LOXL3
uniprot id: A0A6J0AAI9
uniprot id: A0A6J0ABK6
uniprot id: A0A6J2ADA6
uniprot id: A0A6J2AEP2
uniprot id: A0A6J2AHA5
uniprot id: A0A6J2AHQ4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

32536:CRP
gene id: 32536:CRP
uniprot id: A0A6J0A6Y4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

32536:LOC106989573
gene id: 32536:LOC106989573
uniprot id: A0A6J0ACJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NEMF
gene id: 32536:NEMF
uniprot id: A0A6J1ZV56
names: Similarity
messages: Belongs to the NEMF family.

32536:SNX1
gene id: 32536:SNX1
uniprot id: A0A6J0A8Y9
uniprot id: A0A6J0A9U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

32536:H3-4
gene id: 32536:H3-4
uniprot id: A0A6J0A6I8
names: Similarity
messages: Belongs to the histone H3 family.

32536:RSBN1
gene id: 32536:RSBN1
uniprot id: A0A6J1ZAL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

32536:USP20
gene id: 32536:USP20
uniprot id: A0A6J1XFC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP20/USP33 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: centrosome
messages: perinuclear region

32536:UMODL1
gene id: 32536:UMODL1
uniprot id: A0A6J1XXQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:RPS23
gene id: 32536:RPS23
uniprot id: A0A6I9ZU44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Rough endoplasmic reticulum

32536:LOC106985594
gene id: 32536:LOC106985594
uniprot id: A0A6J0A6M2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

32536:KCNA7
gene id: 32536:KCNA7
uniprot id: A0A6J1XMZ6
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106973876
gene id: 32536:LOC106973876
uniprot id: A0A6J2A7E4
names: Similarity
messages: Belongs to the copine family.

32536:LOC106970464
gene id: 32536:LOC106970464
uniprot id: A0A6I9ZHZ5
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:CC1H2orf88
gene id: 32536:CC1H2orf88
uniprot id: A0A6J1YZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

32536:EBF2
gene id: 32536:EBF2
uniprot id: A0A6J2AY70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

32536:LOC106975171
gene id: 32536:LOC106975171
uniprot id: A0A6J1ZMG2
names: Similarity
messages: Belongs to the multicopper oxidase family.

32536:SCTR
gene id: 32536:SCTR
uniprot id: A0A6J1Z2S0
uniprot id: A0A6J1Z429
uniprot id: A0A6J1Z4S7
uniprot id: A0A6J1Z661
names: Subcellular Location Annotation
messages: Membrane

32536:GDPD4
gene id: 32536:GDPD4
uniprot id: A0A6J1XSA5
uniprot id: A0A6J1XSG7
uniprot id: A0A6J1XSL2
uniprot id: A0A6J1XSP1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

32536:LOC106988614
gene id: 32536:LOC106988614
uniprot id: A0A6J1Z1R4
names: Subcellular Location Annotation
messages: Membrane

32536:MDFI
gene id: 32536:MDFI
uniprot id: A0A6J1Z7U6
names: Similarity
messages: Belongs to the MDFI family.

32536:IQSEC1
gene id: 32536:IQSEC1
uniprot id: A0A6J1YN13
names: Similarity
messages: Belongs to the BRAG family.

32536:LOC106979523
gene id: 32536:LOC106979523
uniprot id: A0A6J0A0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CAVIN3
gene id: 32536:CAVIN3
uniprot id: A0A6J1YV75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

32536:HACE1
gene id: 32536:HACE1
uniprot id: A0A6J1Z662
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ATP6AP1
gene id: 32536:ATP6AP1
uniprot id: A0A6J1YWZ2
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

32536:LOC106986885
gene id: 32536:LOC106986885
uniprot id: A0A6J0A8E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106981777
gene id: 32536:LOC106981777
uniprot id: A0A6J0A2F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

32536:ALDH3B1
gene id: 32536:ALDH3B1
uniprot id: A0A6J1Y7P8
uniprot id: A0A6J1Y7Q2
uniprot id: A0A6J1Y7Q6
uniprot id: A0A6J1Y8E1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:GNRH1
gene id: 32536:GNRH1
uniprot id: A0A6J2AV22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GnRH family.
messages: Secreted
messages: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.

32536:RPS19
gene id: 32536:RPS19
uniprot id: A0A6J1XLS2
uniprot id: A0A6J1XLS4
uniprot id: A0A6J1XM08
uniprot id: A0A6J1XM19
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

32536:FLI1
gene id: 32536:FLI1
uniprot id: A0A6J1XJN1
uniprot id: A0A6J1XJN6
uniprot id: A0A6J1XJQ1
uniprot id: A0A6J1XJS2
uniprot id: A0A6J1XJV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:ELOF1
gene id: 32536:ELOF1
uniprot id: A0A6J1YMT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

32536:PDE11A
gene id: 32536:PDE11A
uniprot id: A0A6J1Z375
uniprot id: A0A6J1Z4P8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:RBM3
gene id: 32536:RBM3
uniprot id: A0A6J1YXF9
uniprot id: A0A6J1YZE7
names: Subcellular Location Annotation
messages: Cytoplasm

32536:CD37
gene id: 32536:CD37
uniprot id: A0A6J0AAM0
uniprot id: A0A6J1XMX1
uniprot id: A0A6J1XMY7
uniprot id: A0A6J1XN37
uniprot id: A0A6J1XN61
uniprot id: A0A6J1XN70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:SLC35A2
gene id: 32536:SLC35A2
uniprot id: A0A6J1YXH2
uniprot id: A0A6J1YYT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:LRP6
gene id: 32536:LRP6
uniprot id: A0A6J1XFW9
uniprot id: A0A6J1XFY4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PPIE
gene id: 32536:PPIE
uniprot id: A0A6J0A8H2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.

32536:TJP2
gene id: 32536:TJP2
uniprot id: A0A6J0A452
uniprot id: A0A6J0A6R5
uniprot id: A0A6J0A7U9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

32536:CDC42EP2
gene id: 32536:CDC42EP2
uniprot id: A0A6I9ZM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system
messages: Probably involved in the organization of the actin cytoskeleton.
messages: cytoskeleton

32536:CRK
gene id: 32536:CRK
uniprot id: A0A6J1XD84
names: Similarity
messages: Belongs to the CRK family.

32536:IQCD
gene id: 32536:IQCD
uniprot id: A0A6J1Y512
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

32536:DKK4
gene id: 32536:DKK4
uniprot id: A0A6J0ACY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

32536:MYSM1
gene id: 32536:MYSM1
uniprot id: A0A6I9ZQS4
uniprot id: A0A6J1ZBD6
uniprot id: A0A6J1ZCS9
uniprot id: A0A6J1ZDN5
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

32536:TM7SF2
gene id: 32536:TM7SF2
uniprot id: A0A6J1Y954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

32536:TAAR8
gene id: 32536:TAAR8
uniprot id: A0A6I9ZWY2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:PIK3CG
gene id: 32536:PIK3CG
uniprot id: A0A6J2AFY9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:ZNF213
gene id: 32536:ZNF213
uniprot id: A0A6J1Y2T1
names: Subcellular Location Annotation
messages: Nucleus

32536:CTSA
gene id: 32536:CTSA
uniprot id: A0A6J2A921
uniprot id: A0A6J2ABW7
names: Similarity
messages: Belongs to the peptidase S10 family.

32536:BCL2L1
gene id: 32536:BCL2L1
uniprot id: A0A6J0A788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

32536:LOC106965724
gene id: 32536:LOC106965724
uniprot id: A0A6I9ZCN8
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106966003
gene id: 32536:LOC106966003
uniprot id: A0A6I9ZCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CD28
gene id: 32536:CD28
uniprot id: A0A6I9ZV86
names: Subcellular Location Annotation
messages: Membrane

32536:ABI3
gene id: 32536:ABI3
uniprot id: A0A6J1XBE5
uniprot id: A0A6J1XBF2
names: Similarity
messages: Belongs to the ABI family.

32536:HOXA2
gene id: 32536:HOXA2
uniprot id: A0A6J2ANJ8
names: Subcellular Location Annotation
messages: Nucleus

32536:MAP7D2
gene id: 32536:MAP7D2
uniprot id: A0A6J1YYJ9
uniprot id: A0A6J1YZR1
uniprot id: A0A6J1Z1U1
names: Similarity
messages: Belongs to the MAP7 family.

32536:AP3D1
gene id: 32536:AP3D1
uniprot id: A0A6J1YJA4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

32536:PRR15
gene id: 32536:PRR15
uniprot id: A0A6J2ALY3
names: Similarity
messages: Belongs to the PRR15 family.

32536:RNF185
gene id: 32536:RNF185
uniprot id: A0A6J0A1J0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

32536:GNG8
gene id: 32536:GNG8
uniprot id: A0A6J1XMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:ESRRA
gene id: 32536:ESRRA
uniprot id: A0A6J1Y8B2
uniprot id: A0A6J1Y9J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

32536:LOC106966148
gene id: 32536:LOC106966148
uniprot id: A0A6I9ZGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:HOXD4
gene id: 32536:HOXD4
uniprot id: A0A6J1Z1K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:FLOT1
gene id: 32536:FLOT1
uniprot id: A0A6J1YTZ7
uniprot id: A0A6J1YX95
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Membrane
messages: caveola

32536:RGS7BP
gene id: 32536:RGS7BP
uniprot id: A0A6J1XXB6
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

32536:GRIN1
gene id: 32536:GRIN1
uniprot id: A0A6J1YNV4
uniprot id: A0A6J1YNW2
uniprot id: A0A6J1YNW8
uniprot id: A0A6J1YQ99
uniprot id: A0A6J1YQM7
uniprot id: A0A6J1YQN4
uniprot id: A0A6J1YRW0
uniprot id: A0A6J1YRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:SLC8A2
gene id: 32536:SLC8A2
uniprot id: A0A6J1XMG3
uniprot id: A0A6J1XMQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

32536:LOC106967000
gene id: 32536:LOC106967000
uniprot id: A0A6I9ZHL4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

32536:LCORL
gene id: 32536:LCORL
uniprot id: A0A6J1Y2L6
uniprot id: A0A6J1Y460
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106981251
gene id: 32536:LOC106981251
uniprot id: A0A6J0A1U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RUSF1
gene id: 32536:RUSF1
uniprot id: A0A6I9ZVE4
uniprot id: A0A6I9ZWK5
uniprot id: A0A6I9ZYW5
uniprot id: A0A6I9ZZV5
uniprot id: A0A6J1YTM9
names: Similarity
messages: Belongs to the RUS1 family.

32536:LCK
gene id: 32536:LCK
uniprot id: A0A6J0A3N1
uniprot id: A0A6J1ZFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

32536:TMEM176A
gene id: 32536:TMEM176A
uniprot id: A0A6I9ZSK0
uniprot id: A0A6I9ZUE9
names: Similarity
messages: Belongs to the TMEM176 family.

32536:DDX46
gene id: 32536:DDX46
uniprot id: A0A6J2AVZ8
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:TUBB4B
gene id: 32536:TUBB4B
uniprot id: A0A6J1YQR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

32536:SNRPN
gene id: 32536:SNRPN
uniprot id: A0A6J2A1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

32536:ARMT1
gene id: 32536:ARMT1
uniprot id: A0A6J1Z4M9
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

32536:UROD
gene id: 32536:UROD
uniprot id: A0A6I9ZM81
uniprot id: A0A6I9ZMP1
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

32536:PRRC1
gene id: 32536:PRRC1
uniprot id: A0A6J2AVP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

32536:TAF9
gene id: 32536:TAF9
uniprot id: A0A6J1XUR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

32536:PSMB4
gene id: 32536:PSMB4
uniprot id: A0A6I9ZX93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

32536:MED19
gene id: 32536:MED19
uniprot id: A0A6I9ZW57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:SYT17
gene id: 32536:SYT17
uniprot id: A0A6I9ZI54
uniprot id: A0A6J1Y2Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Membrane

32536:ATOSA
gene id: 32536:ATOSA
uniprot id: A0A6J2A2T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATOS family.
messages: Nucleus

32536:LOC106971296
gene id: 32536:LOC106971296
uniprot id: A0A6I9ZKR8
uniprot id: A0A6I9ZPF5
names: Similarity
messages: Belongs to the cornifelin family.

32536:LOC106982877
gene id: 32536:LOC106982877
uniprot id: A0A6J1Z1Q7
uniprot id: A0A6J1Z306
uniprot id: A0A6J1Z561
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

32536:PSMD4
gene id: 32536:PSMD4
uniprot id: A0A6J1Z3R5
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

32536:TBX21
gene id: 32536:TBX21
uniprot id: A0A6J1XB96
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:AACS
gene id: 32536:AACS
uniprot id: A0A6J1Y583
uniprot id: A0A6J1Y6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

32536:LOC113597708
gene id: 32536:LOC113597708
uniprot id: A0A6J1YYQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

32536:UCMA
gene id: 32536:UCMA
uniprot id: A0A6I9ZIW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UCMA family.
messages: May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
messages: extracellular matrix

32536:CAMK1G
gene id: 32536:CAMK1G
uniprot id: A0A6I9ZZV7
uniprot id: A0A6J0A322
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:PHKA1
gene id: 32536:PHKA1
uniprot id: A0A6J1YW68
uniprot id: A0A6J1YWC3
uniprot id: A0A6J1YXL8
uniprot id: A0A6J1YY74
uniprot id: A0A6J1YZK9
uniprot id: A0A6J1YZL4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.

32536:ARL6
gene id: 32536:ARL6
uniprot id: A0A6J0A4D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

32536:FSCN1
gene id: 32536:FSCN1
uniprot id: A0A6J1Y0T8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

32536:PSMB1
gene id: 32536:PSMB1
uniprot id: A0A6J1Z5D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:DCP1A
gene id: 32536:DCP1A
uniprot id: A0A6J0A5S9
names: Similarity
messages: Belongs to the DCP1 family.

32536:CAPN10
gene id: 32536:CAPN10
uniprot id: A0A6J1Y9Q4
names: Similarity
messages: Belongs to the peptidase C2 family.

32536:RNF146
gene id: 32536:RNF146
uniprot id: A0A6I9ZWV9
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

32536:HS3ST6
gene id: 32536:HS3ST6
uniprot id: A0A6J1Y536
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

32536:CNOT11
gene id: 32536:CNOT11
uniprot id: A0A6I9ZFM8
uniprot id: A0A6J2A9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

32536:RAB39A
gene id: 32536:RAB39A
uniprot id: A0A6J1XIC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

32536:TIE1
gene id: 32536:TIE1
uniprot id: A0A6J1ZEW1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:LOC106977305
gene id: 32536:LOC106977305
uniprot id: A0A6I9ZXH6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

32536:AP1S2
gene id: 32536:AP1S2
uniprot id: A0A6J1YZ77
uniprot id: A0A6J1YZ83
uniprot id: A0A6J1Z0E1
uniprot id: A0A6J1Z178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

32536:FAM76B
gene id: 32536:FAM76B
uniprot id: A0A6I9ZLI9
uniprot id: A0A6I9ZN21
names: Similarity
messages: Belongs to the FAM76 family.

32536:GHSR
gene id: 32536:GHSR
uniprot id: A0A6J1ZJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:PCMT1
gene id: 32536:PCMT1
uniprot id: A0A6J1Z6M0
uniprot id: A0A6J1Z816
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

32536:LOC106987124
gene id: 32536:LOC106987124
uniprot id: A0A6J1YHW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:OSBPL10
gene id: 32536:OSBPL10
uniprot id: A0A6J1XVN9
uniprot id: A0A6J1XW07
uniprot id: A0A6J1XWF6
names: Similarity
messages: Belongs to the OSBP family.

32536:GBA1
gene id: 32536:GBA1
uniprot id: A0A6J1YIC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

32536:PLD2
gene id: 32536:PLD2
uniprot id: A0A6J1YFF4
names: Similarity
messages: Belongs to the phospholipase D family.

32536:MS4A13
gene id: 32536:MS4A13
uniprot id: A0A6I9ZY52
names: Similarity
messages: Belongs to the MS4A family.

32536:INHBB
gene id: 32536:INHBB
uniprot id: A0A6J1Z461
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

32536:SH3YL1
gene id: 32536:SH3YL1
uniprot id: A0A6I9ZNS0
names: Similarity
names: Subunit
messages: Belongs to the SH3YL1 family.
messages: Interacts with SH3D19.

32536:SNRPE
gene id: 32536:SNRPE
uniprot id: A0A6I9ZPK0
uniprot id: A0A6J2AKQ7
uniprot id: A0A6J2AQC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

32536:SEMA4B
gene id: 32536:SEMA4B
uniprot id: A0A6J2A243
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106985471
gene id: 32536:LOC106985471
uniprot id: A0A6J1Z353
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

32536:LOC106986221
gene id: 32536:LOC106986221
uniprot id: A0A6J0A7J5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GUCY2C
gene id: 32536:GUCY2C
uniprot id: A0A6I9ZFM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

32536:FN3K
gene id: 32536:FN3K
uniprot id: A0A6J0A7P7
names: Similarity
messages: Belongs to the fructosamine kinase family.

32536:CALY
gene id: 32536:CALY
uniprot id: A0A6J1Z465
names: Similarity
messages: Belongs to the NSG family.

32536:PKN2
gene id: 32536:PKN2
uniprot id: A0A6J1ZAB5
uniprot id: A0A6J1ZBP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

32536:TPST2
gene id: 32536:TPST2
uniprot id: A0A6J1YNL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

32536:SLC6A17
gene id: 32536:SLC6A17
uniprot id: A0A6J1ZAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

32536:SLC10A4
gene id: 32536:SLC10A4
uniprot id: A0A6J1Z5A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

32536:FGFBP1
gene id: 32536:FGFBP1
uniprot id: A0A6I9ZVB6
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

32536:HDGFL2
gene id: 32536:HDGFL2
uniprot id: A0A6J1YIU7
uniprot id: A0A6J1YKD8
uniprot id: A0A6J1YL63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

32536:HTR1E
gene id: 32536:HTR1E
uniprot id: A0A6I9ZMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:S100A1
gene id: 32536:S100A1
uniprot id: A0A6J0A8P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Mitochondrion

32536:CHRNA5
gene id: 32536:CHRNA5
uniprot id: A0A6J2A305
uniprot id: A0A6J2A3Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:NGB
gene id: 32536:NGB
uniprot id: A0A6J2A101
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.

32536:APP
gene id: 32536:APP
uniprot id: A0A6J1XYA0
uniprot id: A0A6J1XYA4
uniprot id: A0A6J1XYC2
uniprot id: A0A6J1XYC6
uniprot id: A0A6J1XYE9
uniprot id: A0A6J1XYF3
uniprot id: A0A6J1XZA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

32536:PARP11
gene id: 32536:PARP11
uniprot id: A0A6I9ZF88
uniprot id: A0A6I9ZFA8
uniprot id: A0A6J2AMY1
uniprot id: A0A6J2AND1
names: Similarity
messages: Belongs to the ARTD/PARP family.

32536:DDX41
gene id: 32536:DDX41
uniprot id: A0A6I9ZTC2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

32536:SMIM12
gene id: 32536:SMIM12
uniprot id: A0A6I9ZQ17
names: Similarity
messages: Belongs to the SMIM12 family.

32536:EFNA5
gene id: 32536:EFNA5
uniprot id: A0A6J1XIU8
uniprot id: A0A6J1XJ21
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:SOHLH1
gene id: 32536:SOHLH1
uniprot id: A0A6J1YR19
uniprot id: A0A6J1YR20
names: Subcellular Location Annotation
messages: Nucleus

32536:KIF2C
gene id: 32536:KIF2C
uniprot id: A0A6I9ZHL1
uniprot id: A0A6I9ZKI4
uniprot id: A0A6J1ZDN8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:ST8SIA5
gene id: 32536:ST8SIA5
uniprot id: A0A6J2A859
uniprot id: A0A6J2A8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:LOC106988351
gene id: 32536:LOC106988351
uniprot id: A0A6J1YVE2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

32536:DSE
gene id: 32536:DSE
uniprot id: A0A6J1Z6G5
uniprot id: A0A6J1Z968
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

32536:ELK1
gene id: 32536:ELK1
uniprot id: A0A6J1YZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:CD3H12orf43
gene id: 32536:CD3H12orf43
uniprot id: A0A6J1Y473
uniprot id: A0A6J1Y4C9
uniprot id: A0A6J1Y4X5
uniprot id: A0A6J1Y529
uniprot id: A0A6J1Y623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

32536:TMBIM4
gene id: 32536:TMBIM4
uniprot id: A0A6J0A2Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

32536:CSMD3
gene id: 32536:CSMD3
uniprot id: A0A6J1ZQK5
uniprot id: A0A6J1ZQX5
uniprot id: A0A6J1ZT81
uniprot id: A0A6J1ZUM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PSMD1
gene id: 32536:PSMD1
uniprot id: A0A6J1YFR2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

32536:TMTC2
gene id: 32536:TMTC2
uniprot id: A0A6J0A3M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

32536:GBGT1
gene id: 32536:GBGT1
uniprot id: A0A6J1XFR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

32536:IFI27L2
gene id: 32536:IFI27L2
uniprot id: A0A6J1ZXZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

32536:STRN3
gene id: 32536:STRN3
uniprot id: A0A6J1ZV95
uniprot id: A0A6J1ZW20
uniprot id: A0A6J1ZXK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

32536:SLC16A9
gene id: 32536:SLC16A9
uniprot id: A0A6J1ZK14
uniprot id: A0A6J1ZKD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane

32536:TMEM229B
gene id: 32536:TMEM229B
uniprot id: A0A6J1ZYW9
uniprot id: A0A6J2A084
uniprot id: A0A6J2A087
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM229 family.
messages: Membrane

32536:CXCL10
gene id: 32536:CXCL10
uniprot id: A0A6J0A2R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

32536:CAPN5
gene id: 32536:CAPN5
uniprot id: A0A6I9ZUS7
names: Similarity
messages: Belongs to the peptidase C2 family.

32536:ZFP36L2
gene id: 32536:ZFP36L2
uniprot id: A0A6J2AIZ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

32536:RAB3B
gene id: 32536:RAB3B
uniprot id: A0A6J0AA45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

32536:TM4SF4
gene id: 32536:TM4SF4
uniprot id: A0A6I9ZPF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

32536:ADPRH
gene id: 32536:ADPRH
uniprot id: A0A6I9ZHV2
uniprot id: A0A6I9ZJI3
uniprot id: A0A6I9ZJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Belongs to the ADP-ribosylglycohydrolase family.
messages: Secreted

32536:GLDN
gene id: 32536:GLDN
uniprot id: A0A6J1ZZP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ITPR2
gene id: 32536:ITPR2
uniprot id: A0A6J1XGH5
uniprot id: A0A6J1XGH6
uniprot id: A0A6J1XGI2
uniprot id: A0A6J1XGK8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

32536:YIPF6
gene id: 32536:YIPF6
uniprot id: A0A6J1YW58
uniprot id: A0A6J1YZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:SCPEP1
gene id: 32536:SCPEP1
uniprot id: A0A6J0A930
names: Similarity
messages: Belongs to the peptidase S10 family.

32536:LOC106976597
gene id: 32536:LOC106976597
uniprot id: A0A6I9ZRI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:UBAC2
gene id: 32536:UBAC2
uniprot id: A0A6J1ZTR5
uniprot id: A0A6J1ZTR9
uniprot id: A0A6J1ZUW7
names: Subcellular Location Annotation
messages: Membrane

32536:GPR146
gene id: 32536:GPR146
uniprot id: A0A6J1Y018
uniprot id: A0A6J1Y0B3
uniprot id: A0A6J1Y0E6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:TNFSF8
gene id: 32536:TNFSF8
uniprot id: A0A6I9ZUN5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

32536:TEF
gene id: 32536:TEF
uniprot id: A0A6I9ZWU7
uniprot id: A0A6I9ZXT2
uniprot id: A0A6J2A973
uniprot id: A0A6J2AAB5
uniprot id: A0A6J2AD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

32536:CHST12
gene id: 32536:CHST12
uniprot id: A0A6J1Y039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:TSPAN9
gene id: 32536:TSPAN9
uniprot id: A0A6I9ZAP8
uniprot id: A0A6J2AMW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:AMN
gene id: 32536:AMN
uniprot id: A0A6J2A129
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:LOC106986178
gene id: 32536:LOC106986178
uniprot id: A0A6J0A4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:HSPH1
gene id: 32536:HSPH1
uniprot id: A0A6J1ZSB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

32536:LRP12
gene id: 32536:LRP12
uniprot id: A0A6J0A0D2
uniprot id: A0A6J0A1A0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DMC1
gene id: 32536:DMC1
uniprot id: A0A6J2A9L8
uniprot id: A0A6J2AAK6
uniprot id: A0A6J2ADC2
names: Similarity
messages: Belongs to the RecA family.
messages: Belongs to the RecA family. DMC1 subfamily.

32536:IFI44
gene id: 32536:IFI44
uniprot id: A0A6I9ZIB3
names: Similarity
messages: Belongs to the IFI44 family.

32536:HOXC12
gene id: 32536:HOXC12
uniprot id: A0A6J0A4W6
names: Subcellular Location Annotation
messages: Nucleus

32536:GET1
gene id: 32536:GET1
uniprot id: A0A6I9ZD01
uniprot id: A0A6I9ZEE5
uniprot id: A0A6J1XXS9
uniprot id: A0A6J1XXZ9
uniprot id: A0A6J1XYR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:SLC27A1
gene id: 32536:SLC27A1
uniprot id: A0A6J1XNI8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:ZSCAN23
gene id: 32536:ZSCAN23
uniprot id: A0A6J1YT14
uniprot id: A0A6J1YUD6
names: Subcellular Location Annotation
messages: Nucleus

32536:CHST4
gene id: 32536:CHST4
uniprot id: A0A6J0A9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

32536:ANXA6
gene id: 32536:ANXA6
uniprot id: A0A6J2AT69
uniprot id: A0A6J2ATK1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

32536:FXYD5
gene id: 32536:FXYD5
uniprot id: A0A6J1Y6Q0
uniprot id: A0A6J1Y7K8
uniprot id: A0A6J1Y8H0
uniprot id: A0A6J1Y8H3
names: Similarity
messages: Belongs to the FXYD family.

32536:VEGFC
gene id: 32536:VEGFC
uniprot id: A0A6J2ASJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

32536:LOC106969837
gene id: 32536:LOC106969837
uniprot id: A0A6I9ZLI6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:YARS2
gene id: 32536:YARS2
uniprot id: A0A6I9ZSQ5
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:CPT1A
gene id: 32536:CPT1A
uniprot id: A0A6J1Y8V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:CALHM5
gene id: 32536:CALHM5
uniprot id: A0A6J0A6N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

32536:TAF12
gene id: 32536:TAF12
uniprot id: A0A6I9ZJF3
uniprot id: A0A6I9ZMZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

32536:SLC6A15
gene id: 32536:SLC6A15
uniprot id: A0A6J2ABS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

32536:ACR
gene id: 32536:ACR
uniprot id: A0A6J0A992
names: Function
names: Similarity
names: Subunit
messages: Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
messages: Belongs to the peptidase S1 family.
messages: Heavy chain (catalytic) and a light chain linked by two disulfide bonds. Forms a heterodimer with SERPINA5.

32536:PTPRF
gene id: 32536:PTPRF
uniprot id: A0A6J1ZCL8
uniprot id: A0A6J1ZD49
uniprot id: A0A6J1ZD54
uniprot id: A0A6J1ZDU9
uniprot id: A0A6J1ZFY7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

32536:LOC106986430
gene id: 32536:LOC106986430
uniprot id: A0A6J1XHU5
names: Similarity
messages: Belongs to the intermediate filament family.

32536:CENPN
gene id: 32536:CENPN
uniprot id: A0A6J0A5F0
uniprot id: A0A6J2ARX8
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

32536:LOC106972070
gene id: 32536:LOC106972070
uniprot id: A0A6J1XSC2
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

32536:UGT8
gene id: 32536:UGT8
uniprot id: A0A6J1ZPS7
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.

32536:SCG5
gene id: 32536:SCG5
uniprot id: A0A6I9ZJY6
uniprot id: A0A6I9ZLM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

32536:LOC106987114
gene id: 32536:LOC106987114
uniprot id: A0A6J1YGR9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TBX2
gene id: 32536:TBX2
uniprot id: A0A6J1XC59
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:AQP9
gene id: 32536:AQP9
uniprot id: A0A6I9ZP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

32536:CTDP1
gene id: 32536:CTDP1
uniprot id: A0A6J2A923
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

32536:TBC1D7
gene id: 32536:TBC1D7
uniprot id: A0A6J1XU58
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

32536:NDUFV3
gene id: 32536:NDUFV3
uniprot id: A0A6J0A6N3
uniprot id: A0A6J1XXM8
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

32536:SLC34A2
gene id: 32536:SLC34A2
uniprot id: A0A6J1YJB1
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

32536:SPPL3
gene id: 32536:SPPL3
uniprot id: A0A6J1Y469
uniprot id: A0A6J1Y4C2
uniprot id: A0A6J1Y4X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

32536:DGKE
gene id: 32536:DGKE
uniprot id: A0A6J0A9B2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

32536:TARS3
gene id: 32536:TARS3
uniprot id: A0A6J2A4U8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

32536:AMZ2
gene id: 32536:AMZ2
uniprot id: A0A6J1YFA0
uniprot id: A0A6J1YHC8
names: Function
names: Similarity
messages: Belongs to the peptidase M54 family.
messages: Probable zinc metalloprotease.

32536:KIF19
gene id: 32536:KIF19
uniprot id: A0A6J1YF58
uniprot id: A0A6J1YFY9
uniprot id: A0A6J1YH91
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:ZNF326
gene id: 32536:ZNF326
uniprot id: A0A6J1ZB44
uniprot id: A0A6J1ZCJ2
uniprot id: A0A6J1ZCJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AKAP95 family.
messages: Nucleus matrix

32536:TMPO
gene id: 32536:TMPO
uniprot id: A0A6J2AA84
uniprot id: A0A6J2AAI2
uniprot id: A0A6J2AAI7
uniprot id: A0A6J2AE81
uniprot id: A0A6J2AEM7
names: Similarity
messages: Belongs to the LEM family.

32536:PRKACB
gene id: 32536:PRKACB
uniprot id: A0A6I9ZLW8
uniprot id: A0A6I9ZNJ0
uniprot id: A0A6I9ZQ72
uniprot id: A0A6I9ZRJ9
uniprot id: A0A6I9ZRK3
uniprot id: A0A6I9ZSH5
uniprot id: A0A6J1ZAJ3
uniprot id: A0A6J1ZBD7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

32536:PRICKLE1
gene id: 32536:PRICKLE1
uniprot id: A0A6J1XGV0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

32536:SMC3
gene id: 32536:SMC3
uniprot id: A0A6J1ZN59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

32536:STX18
gene id: 32536:STX18
uniprot id: A0A6J1XDC5
uniprot id: A0A6J1XDJ4
uniprot id: A0A6J1XE17
uniprot id: A0A6J1XEU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

32536:LDHB
gene id: 32536:LDHB
uniprot id: A0A6I9ZJC4
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

32536:CAMK2D
gene id: 32536:CAMK2D
uniprot id: A0A6I9ZSJ8
uniprot id: A0A6I9ZU09
uniprot id: A0A6I9ZU14
uniprot id: A0A6I9ZX62
uniprot id: A0A6I9ZX67
uniprot id: A0A6I9ZXH8
uniprot id: A0A6I9ZXI2
uniprot id: A0A6J1ZNI6
uniprot id: A0A6J1ZNN8
uniprot id: A0A6J1ZNT7
uniprot id: A0A6J1ZPG6
uniprot id: A0A6J1ZPL0
uniprot id: A0A6J1ZSD3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

32536:RNGTT
gene id: 32536:RNGTT
uniprot id: A0A6I9ZQH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
messages: In the C-terminal section; belongs to the eukaryotic GTase family.
messages: In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.
messages: Nucleus

32536:HMCN1
gene id: 32536:HMCN1
uniprot id: A0A6I9ZEK0
uniprot id: A0A6J2AK15
uniprot id: A0A6J2AP38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:COLGALT2
gene id: 32536:COLGALT2
uniprot id: A0A6J2AK34
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

32536:HNF1A
gene id: 32536:HNF1A
uniprot id: A0A6J1Y523
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

32536:MDH1B
gene id: 32536:MDH1B
uniprot id: A0A6J0A8L2
uniprot id: A0A6J1YUQ5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

32536:LOC106966574
gene id: 32536:LOC106966574
uniprot id: A0A6J2ASZ9
uniprot id: A0A6J2ATD9
uniprot id: A0A6J2ATE4
uniprot id: A0A6J2AXD6
uniprot id: A0A6J2AY45
uniprot id: A0A6J2AY50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

32536:TARS1
gene id: 32536:TARS1
uniprot id: A0A6J0ABG8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

32536:AXIN2
gene id: 32536:AXIN2
uniprot id: A0A6J1YFU2
names: Subcellular Location Annotation
messages: Cytoplasm

32536:B3GALT2
gene id: 32536:B3GALT2
uniprot id: A0A6I9ZZ27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:LOC113599782
gene id: 32536:LOC113599782
uniprot id: A0A6J1ZHV6
names: Similarity
messages: Belongs to the PRR23 family.

32536:BAMBI
gene id: 32536:BAMBI
uniprot id: A0A6J2ALV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.

32536:ACTMAP
gene id: 32536:ACTMAP
uniprot id: A0A6I9ZXA9
uniprot id: A0A6J1Y602
names: Similarity
messages: Belongs to the ACTMAP family.

32536:EHHADH
gene id: 32536:EHHADH
uniprot id: A0A6I9ZJ69
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

32536:LOC106989923
gene id: 32536:LOC106989923
uniprot id: A0A6J0ABN7
names: Function
names: Subcellular Location Annotation
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
messages: Mitochondrion inner membrane

32536:TACC2
gene id: 32536:TACC2
uniprot id: A0A6J1ZR31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

32536:LOC106989149
gene id: 32536:LOC106989149
uniprot id: A0A6J2AR00
uniprot id: A0A6J2ARF9
uniprot id: A0A6J2AVA7
uniprot id: A0A6J2AVY8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

32536:SLC4A2
gene id: 32536:SLC4A2
uniprot id: A0A6J1YPL3
uniprot id: A0A6J1YPL9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

32536:SLC5A7
gene id: 32536:SLC5A7
uniprot id: A0A6I9ZX46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

32536:LOC106986162
gene id: 32536:LOC106986162
uniprot id: A0A6J0A883
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DIABLO
gene id: 32536:DIABLO
uniprot id: A0A6J1Y728
names: Subcellular Location Annotation
messages: Mitochondrion

32536:IGHMBP2
gene id: 32536:IGHMBP2
uniprot id: A0A6J1Y8X6
uniprot id: A0A6J1YAS4
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

32536:EPHA6
gene id: 32536:EPHA6
uniprot id: A0A6J2ATP2
uniprot id: A0A6J2AU29
uniprot id: A0A6J2AVQ3
uniprot id: A0A6J2AY55
uniprot id: A0A6J2AYV5
names: Subcellular Location Annotation
messages: Membrane

32536:KAT5
gene id: 32536:KAT5
uniprot id: A0A6J1Y7K5
uniprot id: A0A6J1Y7N4
uniprot id: A0A6J1Y8Q0
uniprot id: A0A6J1Y9D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

32536:GRIN3B
gene id: 32536:GRIN3B
uniprot id: A0A6J1YJF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:NFE2L2
gene id: 32536:NFE2L2
uniprot id: A0A6J0AA23
uniprot id: A0A6J0AB34
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

32536:HOXA3
gene id: 32536:HOXA3
uniprot id: A0A6J2AM95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:LOC106966103
gene id: 32536:LOC106966103
uniprot id: A0A6I9ZD41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SPSB3
gene id: 32536:SPSB3
uniprot id: A0A6J1Y3X1
names: Function
names: Similarity
messages: Belongs to the SPSB family.
messages: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

32536:SH2B3
gene id: 32536:SH2B3
uniprot id: A0A6J1Y782
names: Similarity
messages: Belongs to the SH2B adapter family.

32536:GMNN
gene id: 32536:GMNN
uniprot id: A0A6J1XUI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the geminin family.
messages: Nucleus

32536:UBA3
gene id: 32536:UBA3
uniprot id: A0A6J1XRC4
uniprot id: A0A6J1XRH7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

32536:PSD
gene id: 32536:PSD
uniprot id: A0A6I9ZFS3
names: Subcellular Location Annotation
messages: Membrane
messages: ruffle membrane

32536:DOP1B
gene id: 32536:DOP1B
uniprot id: A0A6J1XXZ8
uniprot id: A0A6J1XY39
names: Similarity
messages: Belongs to the dopey family.

32536:LOC106968486
gene id: 32536:LOC106968486
uniprot id: A0A6J2A0G1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

32536:IFT56
gene id: 32536:IFT56
uniprot id: A0A6I9ZJJ4
uniprot id: A0A6J2APW6
uniprot id: A0A6J2AS38
names: Similarity
messages: Belongs to the IFT56 family.

32536:NXT1
gene id: 32536:NXT1
uniprot id: A0A6J2A607
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

32536:PRKAA2
gene id: 32536:PRKAA2
uniprot id: A0A6J1ZCV9
uniprot id: A0A6J1ZEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm
messages: Nucleus

32536:PTPN2
gene id: 32536:PTPN2
uniprot id: A0A6J2A376
uniprot id: A0A6J2A465
uniprot id: A0A6J2A6L3
uniprot id: A0A6J2A785
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

32536:RBL1
gene id: 32536:RBL1
uniprot id: A0A6J2A7N3
uniprot id: A0A6J2A8H5
uniprot id: A0A6J2ABD6
uniprot id: A0A6J2ABV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

32536:FGF3
gene id: 32536:FGF3
uniprot id: A0A6J1Y7H5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:GGNBP2
gene id: 32536:GGNBP2
uniprot id: A0A6J1XC78
uniprot id: A0A6J1XC93
uniprot id: A0A6J1XC99
uniprot id: A0A6J1XCB4
names: Function
messages: May be involved in spermatogenesis.

32536:IDUA
gene id: 32536:IDUA
uniprot id: A0A6J1ZPF0
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

32536:SLC35E3
gene id: 32536:SLC35E3
uniprot id: A0A6I9ZF04
names: Subcellular Location Annotation
messages: Membrane

32536:LYPD2
gene id: 32536:LYPD2
uniprot id: A0A6J1ZSG1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:TAF5L
gene id: 32536:TAF5L
uniprot id: A0A6J1YE41
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

32536:CYRIA
gene id: 32536:CYRIA
uniprot id: A0A6J2B001
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

32536:AK2
gene id: 32536:AK2
uniprot id: A0A6J1ZE25
uniprot id: A0A6J1ZGX0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

32536:DES
gene id: 32536:DES
uniprot id: A0A6I9ZK61
names: Similarity
messages: Belongs to the intermediate filament family.

32536:THOC5
gene id: 32536:THOC5
uniprot id: A0A6J0A3V2
uniprot id: A0A6J0A3V6
uniprot id: A0A6J1YQB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

32536:NPM3
gene id: 32536:NPM3
uniprot id: A0A6J1ZMJ2
names: Similarity
messages: Belongs to the nucleoplasmin family.

32536:FOLH1
gene id: 32536:FOLH1
uniprot id: A0A6J1XTA7
uniprot id: A0A6J1XTL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

32536:LOC106979022
gene id: 32536:LOC106979022
uniprot id: A0A6I9ZZM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GRK7
gene id: 32536:GRK7
uniprot id: A0A6J0A370
uniprot id: A0A6J1ZJ17
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

32536:NUP133
gene id: 32536:NUP133
uniprot id: A0A6J0A2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin Nup133 family.
messages: nuclear pore complex

32536:CBS
gene id: 32536:CBS
uniprot id: A0A6J1XXJ3
uniprot id: A0A6J1XXL8
uniprot id: A0A6J1XXM3
uniprot id: A0A6J1XXX7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

32536:LOC106974828
gene id: 32536:LOC106974828
uniprot id: A0A6I9ZNV8
names: Subcellular Location Annotation
messages: Membrane

32536:ISYNA1
gene id: 32536:ISYNA1
uniprot id: A0A6J1XNU0
uniprot id: A0A6J1XP09
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

32536:PTK2B
gene id: 32536:PTK2B
uniprot id: A0A6J2A8W3
uniprot id: A0A6J2AC56
uniprot id: A0A6J2AC62
uniprot id: A0A6J2AC77
names: Subcellular Location Annotation
messages: Cell membrane
messages: cell cortex
messages: focal adhesion

32536:POLR3H
gene id: 32536:POLR3H
uniprot id: A0A6I9ZWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase which catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

32536:TENT5B
gene id: 32536:TENT5B
uniprot id: A0A6J1ZEK3
names: Similarity
messages: Belongs to the TENT family.

32536:FAM161A
gene id: 32536:FAM161A
uniprot id: A0A6J2AE17
uniprot id: A0A6J2AFF5
uniprot id: A0A6J2AI12
names: Similarity
messages: Belongs to the FAM161 family.

32536:HAPSTR1
gene id: 32536:HAPSTR1
uniprot id: A0A6J1Y2B7
names: Subcellular Location Annotation
messages: Nucleus

32536:NR1H2
gene id: 32536:NR1H2
uniprot id: A0A6J1XK92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:ABCA12
gene id: 32536:ABCA12
uniprot id: A0A6J1YRY9
names: Subcellular Location Annotation
messages: Membrane

32536:POMGNT1
gene id: 32536:POMGNT1
uniprot id: A0A6J1ZC45
uniprot id: A0A6J1ZDG7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

32536:TP63
gene id: 32536:TP63
uniprot id: A0A6I9ZEN4
uniprot id: A0A6I9ZHL6
uniprot id: A0A6I9ZJ87
uniprot id: A0A6I9ZJG1
uniprot id: A0A6J1ZIW5
uniprot id: A0A6J1ZK20
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: Nucleus
messages: PML body
messages: centrosome

32536:SOAT1
gene id: 32536:SOAT1
uniprot id: A0A6I9ZX00
uniprot id: A0A6J2AL20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:CD1H11orf58
gene id: 32536:CD1H11orf58
uniprot id: A0A6I9ZU87
names: Similarity
messages: Belongs to the SMAP family.

32536:CLTCL1
gene id: 32536:CLTCL1
uniprot id: A0A6J1YLG0
uniprot id: A0A6J1YLZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

32536:LOC106977922
gene id: 32536:LOC106977922
uniprot id: A0A6I9ZY70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SPEM2
gene id: 32536:SPEM2
uniprot id: A0A6J1YEE7
uniprot id: A0A6J1YEF6
uniprot id: A0A6J1YF89
uniprot id: A0A6J1YGI1
names: Subcellular Location Annotation
messages: Membrane

32536:NCK1
gene id: 32536:NCK1
uniprot id: A0A6J1ZLN4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

32536:LHFPL6
gene id: 32536:LHFPL6
uniprot id: A0A6J1ZSL1
uniprot id: A0A6J1ZSZ4
names: Subcellular Location Annotation
messages: Membrane

32536:UPF2
gene id: 32536:UPF2
uniprot id: A0A6J2AHC4
names: Subcellular Location Annotation
messages: Cytoplasm

32536:EXTL1
gene id: 32536:EXTL1
uniprot id: A0A6J1ZEQ3
uniprot id: A0A6J1ZGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:BTAF1
gene id: 32536:BTAF1
uniprot id: A0A6I9ZFX1
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106983792
gene id: 32536:LOC106983792
uniprot id: A0A6J0A573
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

32536:MAF1
gene id: 32536:MAF1
uniprot id: A0A6J1ZPJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

32536:TFRC
gene id: 32536:TFRC
uniprot id: A0A6J1ZKX5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

32536:LACTB2
gene id: 32536:LACTB2
uniprot id: A0A6I9ZHX9
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

32536:CDK6
gene id: 32536:CDK6
uniprot id: A0A6J2AGZ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:PLPP1
gene id: 32536:PLPP1
uniprot id: A0A6J1XYS7
uniprot id: A0A6J1XZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

32536:AP3B1
gene id: 32536:AP3B1
uniprot id: A0A6I9ZUA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

32536:ARSJ
gene id: 32536:ARSJ
uniprot id: A0A6I9ZW65
names: Similarity
messages: Belongs to the sulfatase family.

32536:POC5
gene id: 32536:POC5
uniprot id: A0A6I9ZQH3
uniprot id: A0A6I9ZSD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

32536:ANP32B
gene id: 32536:ANP32B
uniprot id: A0A6J1XSB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

32536:SNRPB
gene id: 32536:SNRPB
uniprot id: A0A6J2A6Q7
uniprot id: A0A6J2A7J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

32536:NR2C2
gene id: 32536:NR2C2
uniprot id: A0A6J1Y142
uniprot id: A0A6J1Y230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:AIFM1
gene id: 32536:AIFM1
uniprot id: A0A6J1YZ39
uniprot id: A0A6J1YZY8
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

32536:NAP1L4
gene id: 32536:NAP1L4
uniprot id: A0A6J1YA57
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

32536:CNIH3
gene id: 32536:CNIH3
uniprot id: A0A6J1YB60
uniprot id: A0A6J1YBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

32536:ENPP2
gene id: 32536:ENPP2
uniprot id: A0A6I9ZPW1
uniprot id: A0A6I9ZRF6
uniprot id: A0A6I9ZTF6
uniprot id: A0A6J1ZQI6
uniprot id: A0A6J1ZQV5
uniprot id: A0A6J1ZRM4
uniprot id: A0A6J1ZRM8
uniprot id: A0A6J1ZT61
uniprot id: A0A6J1ZT68
uniprot id: A0A6J1ZUK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

32536:SIN3B
gene id: 32536:SIN3B
uniprot id: A0A6J1XNP5
names: Subcellular Location Annotation
messages: Nucleus

32536:CLU
gene id: 32536:CLU
uniprot id: A0A6I9ZS71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel disulfide-linked heterodimer of an alpha chain and a beta chain. Self-associates and forms higher oligomers.
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
messages: Membrane
messages: Microsome
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol
messages: perinuclear region

32536:PSMB5
gene id: 32536:PSMB5
uniprot id: A0A6J0AB85
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:APH1A
gene id: 32536:APH1A
uniprot id: A0A6J0A565
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

32536:ATP5PD
gene id: 32536:ATP5PD
uniprot id: A0A6J0A6X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

32536:AFMID
gene id: 32536:AFMID
uniprot id: A0A6I9ZZH6
uniprot id: A0A6J1YT55
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynurenine formamidase family.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
messages: Homodimer.
messages: Nucleus
messages: The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.
messages: cytosol

32536:TFB1M
gene id: 32536:TFB1M
uniprot id: A0A6J0A5E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Interacts with mitochondrial RNA polymerase POLRMT. Interacts with TFAM.
messages: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

32536:SPSB2
gene id: 32536:SPSB2
uniprot id: A0A6J2AKM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

32536:RPL36
gene id: 32536:RPL36
uniprot id: A0A6J1YJ52
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

32536:MICOS10
gene id: 32536:MICOS10
uniprot id: A0A6J0A1N7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

32536:RPS17
gene id: 32536:RPS17
uniprot id: A0A6J2A5S0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

32536:PTPN14
gene id: 32536:PTPN14
uniprot id: A0A6I9ZFJ6
uniprot id: A0A6J2ANX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

32536:DSC1
gene id: 32536:DSC1
uniprot id: A0A6J2A3Y4
uniprot id: A0A6J2A3Z7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

32536:IL1A
gene id: 32536:IL1A
uniprot id: A0A6J1XAN2
uniprot id: A0A6J1XAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4. In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage. In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity.
messages: Cytoplasm
messages: Monomer. Interacts with TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion. Interacts with IL1R1. Interacts with S100A13; this interaction is the first step in the export of IL1A, followed by direct translocation of this complex across the plasma membrane.
messages: Nucleus
messages: Secreted

32536:SYNDIG1
gene id: 32536:SYNDIG1
uniprot id: A0A6J2A5W5
uniprot id: A0A6J2A9R8
names: Similarity
messages: Belongs to the CD225/Dispanin family.

32536:LOC106986256
gene id: 32536:LOC106986256
uniprot id: A0A6J0A4S5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SOST
gene id: 32536:SOST
uniprot id: A0A6J1YKG4
names: Similarity
messages: Belongs to the sclerostin family.

32536:NEFL
gene id: 32536:NEFL
uniprot id: A0A6I9ZC93
names: Similarity
messages: Belongs to the intermediate filament family.

32536:MYLK
gene id: 32536:MYLK
uniprot id: A0A6J0A2F9
uniprot id: A0A6J0A5H5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

32536:WT1
gene id: 32536:WT1
uniprot id: A0A6J2AFK7
uniprot id: A0A6J2AG12
uniprot id: A0A6J2AH36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

32536:GNG12
gene id: 32536:GNG12
uniprot id: A0A6J1ZBR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:MLF1
gene id: 32536:MLF1
uniprot id: A0A6I9ZI21
uniprot id: A0A6I9ZJF9
uniprot id: A0A6I9ZL53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

32536:TIMM22
gene id: 32536:TIMM22
uniprot id: A0A6I9ZK28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Membrane
messages: Mitochondrion inner membrane

32536:DTX3L
gene id: 32536:DTX3L
uniprot id: A0A6J0A654
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

32536:BCAT1
gene id: 32536:BCAT1
uniprot id: A0A6I9ZIG7
uniprot id: A0A6I9ZK59
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

32536:ACKR3
gene id: 32536:ACKR3
uniprot id: A0A6I9ZHZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:MIOS
gene id: 32536:MIOS
uniprot id: A0A6I9ZH97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

32536:GRIA4
gene id: 32536:GRIA4
uniprot id: A0A6I9ZRD5
uniprot id: A0A6J1YRF3
uniprot id: A0A6J1YSU1
uniprot id: A0A6J1YT91
uniprot id: A0A6J1YT96
uniprot id: A0A6J1YUJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:YWHAQ
gene id: 32536:YWHAQ
uniprot id: A0A6J2AUC7
names: Function
names: Similarity
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
messages: Belongs to the 14-3-3 family.

32536:POU3F1
gene id: 32536:POU3F1
uniprot id: A0A6J1ZFC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

32536:YY2
gene id: 32536:YY2
uniprot id: A0A6J0A4G5
names: Similarity
messages: Belongs to the YY transcription factor family.

32536:BROX
gene id: 32536:BROX
uniprot id: A0A6I9ZFI6
names: Similarity
messages: Belongs to the BROX family.

32536:ACTR8
gene id: 32536:ACTR8
uniprot id: A0A6J0A9I3
uniprot id: A0A6J1XQI1
uniprot id: A0A6J1XQU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

32536:SCAI
gene id: 32536:SCAI
uniprot id: A0A6J1XEJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

32536:CACNB3
gene id: 32536:CACNB3
uniprot id: A0A6J1XH45
uniprot id: A0A6J1XH60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

32536:DCTN1
gene id: 32536:DCTN1
uniprot id: A0A6J0AAH7
uniprot id: A0A6J2ADR8
uniprot id: A0A6J2AEQ7
uniprot id: A0A6J2AER3
uniprot id: A0A6J2AHC3
uniprot id: A0A6J2AHR6
uniprot id: A0A6J2AHS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: Cytoplasm
messages: cell cortex
messages: cytoskeleton

32536:WDR35
gene id: 32536:WDR35
uniprot id: A0A6J0A0P0
uniprot id: A0A6J0A1K7
names: Function
names: Subcellular Location Annotation
messages: As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking.
messages: centrosome
messages: cilium basal body

32536:POLR3K
gene id: 32536:POLR3K
uniprot id: A0A6I9ZW80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

32536:HCFC2
gene id: 32536:HCFC2
uniprot id: A0A6J2AA13
uniprot id: A0A6J2AAA4
uniprot id: A0A6J2AAA9
uniprot id: A0A6J2AB84
uniprot id: A0A6J2AED3
names: Subcellular Location Annotation
messages: Nucleus

32536:IRF8
gene id: 32536:IRF8
uniprot id: A0A6J2AQ57
uniprot id: A0A6J2AS63
names: Subcellular Location Annotation
messages: Nucleus

32536:TRRAP
gene id: 32536:TRRAP
uniprot id: A0A6J1XZE8
uniprot id: A0A6J1XZN8
uniprot id: A0A6J1XZP4
uniprot id: A0A6J1XZS2
uniprot id: A0A6J1Y013
uniprot id: A0A6J1Y019
uniprot id: A0A6J1Y024
uniprot id: A0A6J1Y0K5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

32536:GPI
gene id: 32536:GPI
uniprot id: A0A6J1Y8J7
names: Similarity
messages: Belongs to the GPI family.

32536:CRX
gene id: 32536:CRX
uniprot id: A0A6J1XMR9
names: Subcellular Location Annotation
messages: Nucleus

32536:NXPE3
gene id: 32536:NXPE3
uniprot id: A0A6I9ZM13
uniprot id: A0A6J2AVX6
names: Similarity
messages: Belongs to the NXPE family.

32536:SLC25A4
gene id: 32536:SLC25A4
uniprot id: A0A6J2AUC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

32536:PEX14
gene id: 32536:PEX14
uniprot id: A0A6J1ZFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.
messages: Peroxisome membrane

32536:PTEN
gene id: 32536:PTEN
uniprot id: A0A6J1YKQ3
uniprot id: A0A6J1YLV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine-phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3-phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4.
messages: Belongs to the PTEN phosphatase protein family.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Postsynaptic density
messages: dendritic spine

32536:GAPDHS
gene id: 32536:GAPDHS
uniprot id: A0A6J1Y6N7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

32536:LIPA
gene id: 32536:LIPA
uniprot id: A0A6J1YNN3
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

32536:EEF1A1
gene id: 32536:EEF1A1
uniprot id: A0A6J1ZA85
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

32536:ZC3H12C
gene id: 32536:ZC3H12C
uniprot id: A0A6J1XIE8
uniprot id: A0A6J1XII6
names: Similarity
messages: Belongs to the ZC3H12 family.

32536:MAGI1
gene id: 32536:MAGI1
uniprot id: A0A6J1XR13
uniprot id: A0A6J1XR18
uniprot id: A0A6J1XR20
uniprot id: A0A6J1XR23
uniprot id: A0A6J1XR24
uniprot id: A0A6J1XR28
uniprot id: A0A6J1XR31
uniprot id: A0A6J1XR32
uniprot id: A0A6J1XR94
uniprot id: A0A6J1XR97
uniprot id: A0A6J1XRA0
uniprot id: A0A6J1XRA5
uniprot id: A0A6J1XRB0
uniprot id: A0A6J1XRE4
uniprot id: A0A6J1XRE9
uniprot id: A0A6J1XRF8
names: Subcellular Location Annotation
messages: Membrane

32536:STOM
gene id: 32536:STOM
uniprot id: A0A6J1XEA1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

32536:APPL2
gene id: 32536:APPL2
uniprot id: A0A6I9ZLM2
uniprot id: A0A6I9ZQF9
uniprot id: A0A6J2AA88
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: Nucleus
messages: phagosome
messages: ruffle

32536:C8A
gene id: 32536:C8A
uniprot id: A0A6I9ZSP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:ANAPC13
gene id: 32536:ANAPC13
uniprot id: A0A6J0A980
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

32536:APLP1
gene id: 32536:APLP1
uniprot id: A0A6J1Y6C6
uniprot id: A0A6J1Y6D0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:LOC106972303
gene id: 32536:LOC106972303
uniprot id: A0A6J1YHJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

32536:ADAMTS6
gene id: 32536:ADAMTS6
uniprot id: A0A6J1XX30
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:RARS2
gene id: 32536:RARS2
uniprot id: A0A6J1Z6E6
uniprot id: A0A6J1Z6F1
uniprot id: A0A6J1Z7S9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:RNF20
gene id: 32536:RNF20
uniprot id: A0A6J1XSG9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus

32536:PDXK
gene id: 32536:PDXK
uniprot id: A0A6J1XXG7
names: Similarity
messages: Belongs to the pyridoxine kinase family.

32536:MFAP1
gene id: 32536:MFAP1
uniprot id: A0A6I9ZI27
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.

32536:FABP6
gene id: 32536:FABP6
uniprot id: A0A6J1X6U2
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

32536:ACSL1
gene id: 32536:ACSL1
uniprot id: A0A6J2ASQ4
uniprot id: A0A6J2AUB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

32536:SLC7A1
gene id: 32536:SLC7A1
uniprot id: A0A6J1ZUY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

32536:RNASE10
gene id: 32536:RNASE10
uniprot id: A0A6J1ZVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

32536:LOC106977079
gene id: 32536:LOC106977079
uniprot id: A0A6I9ZTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTF2H2 family.
messages: Nucleus

32536:TMEM176B
gene id: 32536:TMEM176B
uniprot id: A0A6J1YPC0
names: Similarity
messages: Belongs to the TMEM176 family.

32536:LOC106969346
gene id: 32536:LOC106969346
uniprot id: A0A6I9ZLE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CDKN3
gene id: 32536:CDKN3
uniprot id: A0A6J1ZVG6
uniprot id: A0A6J1ZVS3
uniprot id: A0A6J1ZWM7
uniprot id: A0A6J1ZZJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

32536:ANXA4
gene id: 32536:ANXA4
uniprot id: A0A6J2AHS3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Zymogen granule membrane

32536:FTSJ3
gene id: 32536:FTSJ3
uniprot id: A0A6I9ZUT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

32536:LRP8
gene id: 32536:LRP8
uniprot id: A0A6J1ZBL8
uniprot id: A0A6J1ZCE2
uniprot id: A0A6J1ZCE7
uniprot id: A0A6J1ZD11
uniprot id: A0A6J1ZD16
uniprot id: A0A6J1ZDX6
uniprot id: A0A6J1ZDY2
uniprot id: A0A6J1ZF27
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CENPQ
gene id: 32536:CENPQ
uniprot id: A0A6I9ZSH2
uniprot id: A0A6J1Z821
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-Q/OKP1 family.
messages: Nucleus

32536:MICAL1
gene id: 32536:MICAL1
uniprot id: A0A6I9ZFZ1
uniprot id: A0A6I9ZHB4
uniprot id: A0A6J1Z611
uniprot id: A0A6J1Z6R3
uniprot id: A0A6J1Z9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

32536:KCNC1
gene id: 32536:KCNC1
uniprot id: A0A6I9ZXD3
names: Subcellular Location Annotation
messages: Membrane

32536:INTS11
gene id: 32536:INTS11
uniprot id: A0A6J1ZIS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

32536:VPS72
gene id: 32536:VPS72
uniprot id: A0A6I9ZWD6
names: Function
names: Similarity
messages: Belongs to the VPS72/YL1 family.
messages: Deposition-and-exchange histone chaperone specific for H2AZ1, specifically chaperones H2AZ1 and deposits it into nucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AZ1/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling.

32536:PDE7B
gene id: 32536:PDE7B
uniprot id: A0A6J1Z545
uniprot id: A0A6J1Z5H5
uniprot id: A0A6J1Z8G2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:AK3
gene id: 32536:AK3
uniprot id: A0A6J1XXD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

32536:UROC1
gene id: 32536:UROC1
uniprot id: A0A6J1YKH2
names: Similarity
messages: Belongs to the urocanase family.

32536:PTHLH
gene id: 32536:PTHLH
uniprot id: A0A6J1XGK1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

32536:PTDSS2
gene id: 32536:PTDSS2
uniprot id: A0A6J1YR90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:SH2D1A
gene id: 32536:SH2D1A
uniprot id: A0A6J1YZ84
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

32536:LOC106976318
gene id: 32536:LOC106976318
uniprot id: A0A6J1XTZ1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:CDC42BPG
gene id: 32536:CDC42BPG
uniprot id: A0A6J1Y7U4
uniprot id: A0A6J1Y7W2
uniprot id: A0A6J1Y7W5
uniprot id: A0A6J1Y8L7
uniprot id: A0A6J1Y8M2
uniprot id: A0A6J1Y9M0
uniprot id: A0A6J1Y9N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm

32536:DSG4
gene id: 32536:DSG4
uniprot id: A0A6J2A4Z6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

32536:CMTM7
gene id: 32536:CMTM7
uniprot id: A0A6J1XW48
uniprot id: A0A6J1XWF0
names: Subcellular Location Annotation
messages: Membrane

32536:ATG3
gene id: 32536:ATG3
uniprot id: A0A6I9ZM27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG3 family.
messages: Cytoplasm

32536:TOMM20
gene id: 32536:TOMM20
uniprot id: A0A6J1YDH6
uniprot id: A0A6J1YE45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:GALT
gene id: 32536:GALT
uniprot id: A0A6I9ZRL3
uniprot id: A0A6I9ZTP8
uniprot id: A0A6J1XRI4
uniprot id: A0A6J1XRP9
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.

32536:RDH8
gene id: 32536:RDH8
uniprot id: A0A6J1YLR4
uniprot id: A0A6J1YPI1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:GPX1
gene id: 32536:GPX1
uniprot id: A0A6I9ZVP0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

32536:ITGAV
gene id: 32536:ITGAV
uniprot id: A0A6J1Z0L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

32536:CEP70
gene id: 32536:CEP70
uniprot id: A0A6J0A6C8
uniprot id: A0A6J1ZJI0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

32536:LOC106983090
gene id: 32536:LOC106983090
uniprot id: A0A6J1XHX6
uniprot id: A0A6J1XHZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

32536:IFNK
gene id: 32536:IFNK
uniprot id: A0A6J1XR96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

32536:LOC113595645
gene id: 32536:LOC113595645
uniprot id: A0A6J1YAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

32536:KIF5B
gene id: 32536:KIF5B
uniprot id: A0A6I9ZX06
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:ATP5F1A
gene id: 32536:ATP5F1A
uniprot id: A0A6I9ZN03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

32536:OXA1L
gene id: 32536:OXA1L
uniprot id: A0A6J1ZUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

32536:LOC106981160
gene id: 32536:LOC106981160
uniprot id: A0A6I9ZYI1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TRIM45
gene id: 32536:TRIM45
uniprot id: A0A6I9ZL80
uniprot id: A0A6J1ZGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

32536:BCLAF1
gene id: 32536:BCLAF1
uniprot id: A0A6J0A1V4
uniprot id: A0A6J0A4M5
uniprot id: A0A6J0A546
uniprot id: A0A6J0A5Q2
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

32536:LIF
gene id: 32536:LIF
uniprot id: A0A6J0A4L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
messages: Secreted

32536:LOC106981561
gene id: 32536:LOC106981561
uniprot id: A0A6J0A2S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NCAPD3
gene id: 32536:NCAPD3
uniprot id: A0A6I9ZPB9
uniprot id: A0A6I9ZQX7
uniprot id: A0A6J1XJQ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

32536:MATK
gene id: 32536:MATK
uniprot id: A0A6J1YJ68
uniprot id: A0A6J1YJ70
uniprot id: A0A6J1YK47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:MAML1
gene id: 32536:MAML1
uniprot id: A0A6J2AWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

32536:SEC24D
gene id: 32536:SEC24D
uniprot id: A0A6J1ZPH8
uniprot id: A0A6J1ZQ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

32536:CTLA4
gene id: 32536:CTLA4
uniprot id: A0A6I9ZRP5
uniprot id: A0A6I9ZWQ5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

32536:LRP10
gene id: 32536:LRP10
uniprot id: A0A6J0AA64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:IMPDH1
gene id: 32536:IMPDH1
uniprot id: A0A6J2ARN5
uniprot id: A0A6J2AS45
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

32536:ARF5
gene id: 32536:ARF5
uniprot id: A0A6J2ARM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

32536:GSG1
gene id: 32536:GSG1
uniprot id: A0A6I9ZB34
uniprot id: A0A6I9ZCJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

32536:SERPINB3
gene id: 32536:SERPINB3
uniprot id: A0A6J0A3P4
names: Similarity
messages: Belongs to the serpin family.

32536:SNX10
gene id: 32536:SNX10
uniprot id: A0A6J2ANI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

32536:MED13
gene id: 32536:MED13
uniprot id: A0A6J1XC87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:RPS27
gene id: 32536:RPS27
uniprot id: A0A6J1YI67
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

32536:PPP2R2D
gene id: 32536:PPP2R2D
uniprot id: A0A6J1ZP91
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

32536:DLD
gene id: 32536:DLD
uniprot id: A0A6I9ZYL9
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

32536:MRPS10
gene id: 32536:MRPS10
uniprot id: A0A6I9ZSN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

32536:LHFPL4
gene id: 32536:LHFPL4
uniprot id: A0A6I9ZM85
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106986232
gene id: 32536:LOC106986232
uniprot id: A0A6J0A8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:AGBL5
gene id: 32536:AGBL5
uniprot id: A0A6I9ZHA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

32536:MYLK2
gene id: 32536:MYLK2
uniprot id: A0A6J0A812
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

32536:GNA11
gene id: 32536:GNA11
uniprot id: A0A6J1YIM7
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

32536:FAM178B
gene id: 32536:FAM178B
uniprot id: A0A6I9ZRN4
uniprot id: A0A6I9ZT45
uniprot id: A0A6J2AG37
uniprot id: A0A6J2AIN0
uniprot id: A0A6J2AJ18
names: Similarity
messages: Belongs to the FAM178 family.

32536:LHX9
gene id: 32536:LHX9
uniprot id: A0A6J2AK80
uniprot id: A0A6J2APV4
names: Subcellular Location Annotation
messages: Nucleus

32536:COL4A2
gene id: 32536:COL4A2
uniprot id: A0A6J1ZV32
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

32536:TMED3
gene id: 32536:TMED3
uniprot id: A0A6J2A2P2
uniprot id: A0A6J2A2W3
uniprot id: A0A6J2A669
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

32536:SFXN4
gene id: 32536:SFXN4
uniprot id: A0A6J1ZNQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

32536:CLCN4
gene id: 32536:CLCN4
uniprot id: A0A6J1YZ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

32536:ARL8A
gene id: 32536:ARL8A
uniprot id: A0A6J2AKD7
uniprot id: A0A6J2AQ29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: spindle

32536:RDH11
gene id: 32536:RDH11
uniprot id: A0A6I9ZP64
uniprot id: A0A6I9ZPZ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:LGI4
gene id: 32536:LGI4
uniprot id: A0A6J1Y7E3
names: Subcellular Location Annotation
messages: Secreted

32536:CNIH4
gene id: 32536:CNIH4
uniprot id: A0A6J1YAJ2
uniprot id: A0A6J1YBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

32536:DAO
gene id: 32536:DAO
uniprot id: A0A6I9ZTX3
uniprot id: A0A6I9ZXJ3
uniprot id: A0A6I9ZYM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

32536:GPR25
gene id: 32536:GPR25
uniprot id: A0A6J2ALQ3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:MED30
gene id: 32536:MED30
uniprot id: A0A6I9ZTG2
uniprot id: A0A6J1ZQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

32536:UPF3A
gene id: 32536:UPF3A
uniprot id: A0A6J1ZU52
uniprot id: A0A6J1ZU55
uniprot id: A0A6J1ZUK8
uniprot id: A0A6J1ZVC9
uniprot id: A0A6J1ZVD0
uniprot id: A0A6J1ZWW8
uniprot id: A0A6J1ZYA9
uniprot id: A0A6J1ZYB4
names: Similarity
messages: Belongs to the RENT3 family.

32536:DIS3L2
gene id: 32536:DIS3L2
uniprot id: A0A6J1YEX5
uniprot id: A0A6J1YF00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

32536:SLC1A7
gene id: 32536:SLC1A7
uniprot id: A0A6I9ZSR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:EXTL3
gene id: 32536:EXTL3
uniprot id: A0A6J2AAJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:BBS2
gene id: 32536:BBS2
uniprot id: A0A6J1Y788
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

32536:DYNLT2
gene id: 32536:DYNLT2
uniprot id: A0A6J1Z5F4
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

32536:MANEA
gene id: 32536:MANEA
uniprot id: A0A6I9ZX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:SLC5A5
gene id: 32536:SLC5A5
uniprot id: A0A6J1XNM8
uniprot id: A0A6J1XNN9
uniprot id: A0A6J1XNW8
uniprot id: A0A6J1XNX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

32536:LOC106986888
gene id: 32536:LOC106986888
uniprot id: A0A6J0A864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:AGAP3
gene id: 32536:AGAP3
uniprot id: A0A6J1YPM5
names: Similarity
messages: Belongs to the centaurin gamma-like family.

32536:KIFC2
gene id: 32536:KIFC2
uniprot id: A0A6J1ZPF6
uniprot id: A0A6J1ZQI1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DEFB116
gene id: 32536:DEFB116
uniprot id: A0A6J0A6X2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

32536:GADD45B
gene id: 32536:GADD45B
uniprot id: A0A6J1YJX9
names: Similarity
messages: Belongs to the GADD45 family.

32536:NIPBL
gene id: 32536:NIPBL
uniprot id: A0A6J2ASA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

32536:FPGS
gene id: 32536:FPGS
uniprot id: A0A6J1XES5
uniprot id: A0A6J1XEU0
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

32536:FA2H
gene id: 32536:FA2H
uniprot id: A0A6J0ABQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:GRIK3
gene id: 32536:GRIK3
uniprot id: A0A6J1ZDA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:TNP1
gene id: 32536:TNP1
uniprot id: A0A6I9ZIT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 1 family.
messages: Chromosome
messages: Nucleus

32536:FYTTD1
gene id: 32536:FYTTD1
uniprot id: A0A6J0A1F4
uniprot id: A0A6J1ZHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle
messages: nucleoplasm

32536:PIK3R1
gene id: 32536:PIK3R1
uniprot id: A0A6J1XVQ9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

32536:BMP15
gene id: 32536:BMP15
uniprot id: A0A6I9ZSH6
names: Similarity
messages: Belongs to the TGF-beta family.

32536:COG8
gene id: 32536:COG8
uniprot id: A0A6J2ATM7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

32536:LOC106986753
gene id: 32536:LOC106986753
uniprot id: A0A6J1XBU7
names: Similarity
messages: Belongs to the NDK family.

32536:GRHL1
gene id: 32536:GRHL1
uniprot id: A0A6J2AUE1
uniprot id: A0A6J2AUU6
uniprot id: A0A6J2AWK8
names: Subcellular Location Annotation
messages: Nucleus

32536:RCE1
gene id: 32536:RCE1
uniprot id: A0A6J1YAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:SPTSSB
gene id: 32536:SPTSSB
uniprot id: A0A6I9ZL64
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:ANXA2
gene id: 32536:ANXA2
uniprot id: A0A6I9ZS64
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Membrane
messages: basement membrane

32536:LMBR1L
gene id: 32536:LMBR1L
uniprot id: A0A6I9ZLA0
names: Similarity
messages: Belongs to the LIMR family.

32536:PPP1R10
gene id: 32536:PPP1R10
uniprot id: A0A6I9ZH00
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.

32536:DUSP9
gene id: 32536:DUSP9
uniprot id: A0A6J1YV86
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

32536:ZCCHC4
gene id: 32536:ZCCHC4
uniprot id: A0A6I9ZU42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZCCHC4 family.
messages: Cytoplasm
messages: nucleolus

32536:POU5F2
gene id: 32536:POU5F2
uniprot id: A0A6I9ZKD3
names: Subcellular Location Annotation
messages: Nucleus

32536:FOXI1
gene id: 32536:FOXI1
uniprot id: A0A6I9ZGE1
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106969731
gene id: 32536:LOC106969731
uniprot id: A0A6I9ZLE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MYO1D
gene id: 32536:MYO1D
uniprot id: A0A6J0A687
uniprot id: A0A6J1XCJ8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

32536:SLC35A3
gene id: 32536:SLC35A3
uniprot id: A0A6J1ZAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:LOC106973243
gene id: 32536:LOC106973243
uniprot id: A0A6I9ZLR0
uniprot id: A0A6J1ZDG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

32536:MLST8
gene id: 32536:MLST8
uniprot id: A0A6J1Y383
uniprot id: A0A6J1Y4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

32536:CFAP299
gene id: 32536:CFAP299
uniprot id: A0A6I9ZX02
uniprot id: A0A6J1ZD71
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

32536:TATDN1
gene id: 32536:TATDN1
uniprot id: A0A6J0A521
uniprot id: A0A6J1ZQC7
uniprot id: A0A6J1ZQQ0
uniprot id: A0A6J1ZRH3
uniprot id: A0A6J1ZRH7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

32536:RMND1
gene id: 32536:RMND1
uniprot id: A0A6I9ZUJ1
uniprot id: A0A6I9ZVL8
names: Similarity
messages: Belongs to the RMD1/sif2 family.

32536:OPRM1
gene id: 32536:OPRM1
uniprot id: A0A6I9ZSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

32536:IST1
gene id: 32536:IST1
uniprot id: A0A6J0A885
uniprot id: A0A6J2APK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IST1 family.
messages: Cytoplasmic vesicle
messages: Nucleus envelope

32536:IMPACT
gene id: 32536:IMPACT
uniprot id: A0A6J2A7G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

32536:L3MBTL4
gene id: 32536:L3MBTL4
uniprot id: A0A6J2A4K4
uniprot id: A0A6J2A7K1
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106983409
gene id: 32536:LOC106983409
uniprot id: A0A6J0A4R7
names: Subcellular Location Annotation
messages: Nucleus

32536:AGTPBP1
gene id: 32536:AGTPBP1
uniprot id: A0A6J1YG47
uniprot id: A0A6J1YG48
uniprot id: A0A6J1YGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

32536:LOC106987642
gene id: 32536:LOC106987642
uniprot id: A0A6J0A6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

32536:CDK2
gene id: 32536:CDK2
uniprot id: A0A6J0A5R3
uniprot id: A0A6J0A898
uniprot id: A0A6J2AFK3
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:ACER3
gene id: 32536:ACER3
uniprot id: A0A6J1XS89
uniprot id: A0A6J1XSM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:SLC30A3
gene id: 32536:SLC30A3
uniprot id: A0A6J1X6F5
uniprot id: A0A6J1X6F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

32536:ALKBH5
gene id: 32536:ALKBH5
uniprot id: A0A6J0A2Z2
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

32536:RORB
gene id: 32536:RORB
uniprot id: A0A6J1XWK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:SSR4
gene id: 32536:SSR4
uniprot id: A0A6J1YV97
uniprot id: A0A6J1YWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-delta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

32536:FGFR4
gene id: 32536:FGFR4
uniprot id: A0A6I9ZTA8
uniprot id: A0A6J1XFI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

32536:PARP16
gene id: 32536:PARP16
uniprot id: A0A6I9ZYL4
uniprot id: A0A6J2A0V2
uniprot id: A0A6J2A1N1
names: Similarity
messages: Belongs to the ARTD/PARP family.

32536:OAT
gene id: 32536:OAT
uniprot id: A0A6J1ZP03
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

32536:OXCT1
gene id: 32536:OXCT1
uniprot id: A0A6I9ZLM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

32536:LOC106981141
gene id: 32536:LOC106981141
uniprot id: A0A6J0A1P4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CA3H2orf49
gene id: 32536:CA3H2orf49
uniprot id: A0A6I9ZY11
uniprot id: A0A6I9ZY94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

32536:TRIM56
gene id: 32536:TRIM56
uniprot id: A0A6J1Y036
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

32536:SBK1
gene id: 32536:SBK1
uniprot id: A0A6J1YS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

32536:HOOK1
gene id: 32536:HOOK1
uniprot id: A0A6J1ZC47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

32536:SUCLA2
gene id: 32536:SUCLA2
uniprot id: A0A6J1ZU01
uniprot id: A0A6J1ZVH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

32536:TMEM91
gene id: 32536:TMEM91
uniprot id: A0A6J1XLL7
uniprot id: A0A6J1XLT8
uniprot id: A0A6J1XLV0
names: Similarity
messages: Belongs to the CD225/Dispanin family.

32536:NKX2-5
gene id: 32536:NKX2-5
uniprot id: A0A6J1XDC0
names: Subcellular Location Annotation
messages: Nucleus

32536:RPS20
gene id: 32536:RPS20
uniprot id: A0A6J0A489
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

32536:SIVA1
gene id: 32536:SIVA1
uniprot id: A0A6J1ZYQ0
uniprot id: A0A6J2A2E9
names: Function
names: PTM
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus
messages: Phosphorylated by ABL2/ARG in response to oxidative stress.

32536:GRIA2
gene id: 32536:GRIA2
uniprot id: A0A6J0A571
uniprot id: A0A6J0A806
uniprot id: A0A6J0A8U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

32536:LTA4H
gene id: 32536:LTA4H
uniprot id: A0A6I9ZSM4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

32536:MAL
gene id: 32536:MAL
uniprot id: A0A6J1XAI9
names: Subcellular Location Annotation
messages: Membrane

32536:INTS9
gene id: 32536:INTS9
uniprot id: A0A6J0A0V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

32536:FGR
gene id: 32536:FGR
uniprot id: A0A6J1ZHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:EZH1
gene id: 32536:EZH1
uniprot id: A0A6I9ZMJ3
uniprot id: A0A6J1YIB7
names: Subcellular Location Annotation
messages: Nucleus

32536:CDC123
gene id: 32536:CDC123
uniprot id: A0A6I9ZIW7
uniprot id: A0A6I9ZKH7
uniprot id: A0A6I9ZP44
uniprot id: A0A6J2AII9
uniprot id: A0A6J2AL07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

32536:CACNA2D1
gene id: 32536:CACNA2D1
uniprot id: A0A6J2ACJ9
uniprot id: A0A6J2ACK6
uniprot id: A0A6J2ADK1
uniprot id: A0A6J2AG63
uniprot id: A0A6J2AG68
uniprot id: A0A6J2AGL8
uniprot id: A0A6J2AGM2
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

32536:SPCS1
gene id: 32536:SPCS1
uniprot id: A0A6J1XQL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:SLAIN2
gene id: 32536:SLAIN2
uniprot id: A0A6J1Z594
uniprot id: A0A6J1Z799
names: Similarity
messages: Belongs to the SLAIN motif-containing family.

32536:SCD
gene id: 32536:SCD
uniprot id: A0A6I9ZHG0
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

32536:DVL3
gene id: 32536:DVL3
uniprot id: A0A6J1ZLK2
names: Similarity
messages: Belongs to the DSH family.

32536:PGPEP1
gene id: 32536:PGPEP1
uniprot id: A0A6I9ZL20
uniprot id: A0A6J1XNU8
uniprot id: A0A6J1XP34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

32536:ZNF280D
gene id: 32536:ZNF280D
uniprot id: A0A6J1ZZZ2
uniprot id: A0A6J2A0A0
uniprot id: A0A6J2A103
uniprot id: A0A6J2A108
uniprot id: A0A6J2A403
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

32536:MTR
gene id: 32536:MTR
uniprot id: A0A6J1YCM6
uniprot id: A0A6J1YD80
uniprot id: A0A6J1YDX8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

32536:MLLT1
gene id: 32536:MLLT1
uniprot id: A0A6J1YJB9
uniprot id: A0A6J1YKC0
names: Subcellular Location Annotation
messages: Nucleus

32536:PSKH1
gene id: 32536:PSKH1
uniprot id: A0A6J2APR6
uniprot id: A0A6J2ATY9
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:CHRNA4
gene id: 32536:CHRNA4
uniprot id: A0A6J1YCG9
uniprot id: A0A6J1YD38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:HEBP2
gene id: 32536:HEBP2
uniprot id: A0A6J1Z8D6
names: Similarity
messages: Belongs to the HEBP family.

32536:P3H2
gene id: 32536:P3H2
uniprot id: A0A6I9ZJ94
names: Similarity
messages: Belongs to the leprecan family.

32536:EP300
gene id: 32536:EP300
uniprot id: A0A6J0A074
names: Subcellular Location Annotation
messages: Cytoplasm

32536:PROKR1
gene id: 32536:PROKR1
uniprot id: A0A6I9ZIR1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:SLC24A4
gene id: 32536:SLC24A4
uniprot id: A0A6J1ZXE8
uniprot id: A0A6J1ZYM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

32536:MAP1LC3C
gene id: 32536:MAP1LC3C
uniprot id: A0A6I9ZRH3
names: Similarity
messages: Belongs to the ATG8 family.

32536:TRAPPC4
gene id: 32536:TRAPPC4
uniprot id: A0A6J0A226
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

32536:FOXJ1
gene id: 32536:FOXJ1
uniprot id: A0A6J1YWF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FOXJ1 family.
messages: Nucleus

32536:CAPZA1
gene id: 32536:CAPZA1
uniprot id: A0A6I9ZLP8
uniprot id: A0A6J1ZAN7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

32536:SDHC
gene id: 32536:SDHC
uniprot id: A0A6I9ZZ09
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

32536:PYGM
gene id: 32536:PYGM
uniprot id: A0A6J1Y826
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

32536:CLCN7
gene id: 32536:CLCN7
uniprot id: A0A6J1Y379
uniprot id: A0A6J1Y590
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

32536:MYO1H
gene id: 32536:MYO1H
uniprot id: A0A6I9ZWC5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

32536:TBCCD1
gene id: 32536:TBCCD1
uniprot id: A0A6J1ZK60
uniprot id: A0A6J1ZL97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

32536:EEF1AKMT2
gene id: 32536:EEF1AKMT2
uniprot id: A0A6J1ZP13
uniprot id: A0A6J1ZR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

32536:KRT23
gene id: 32536:KRT23
uniprot id: A0A6J0AC65
names: Similarity
messages: Belongs to the intermediate filament family.

32536:THBS1
gene id: 32536:THBS1
uniprot id: A0A6J0A0U2
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LDAF1
gene id: 32536:LDAF1
uniprot id: A0A6I9ZN80
uniprot id: A0A6J1Y273
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

32536:PI4K2B
gene id: 32536:PI4K2B
uniprot id: A0A6J1YIX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

32536:DBNL
gene id: 32536:DBNL
uniprot id: A0A6J1Y9T5
uniprot id: A0A6J1YAH2
uniprot id: A0A6J1YBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Early endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

32536:FOXA1
gene id: 32536:FOXA1
uniprot id: A0A6J1ZV06
names: Subcellular Location Annotation
messages: Nucleus

32536:ADA2
gene id: 32536:ADA2
uniprot id: A0A6I9ZDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

32536:NR4A3
gene id: 32536:NR4A3
uniprot id: A0A6J1XS11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:CORO6
gene id: 32536:CORO6
uniprot id: A0A6I9ZK99
names: Similarity
messages: Belongs to the WD repeat coronin family.

32536:PDYN
gene id: 32536:PDYN
uniprot id: A0A6J2AAY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opioid activity and may have anti-apoptotic effect.
messages: Secreted

32536:LOC106979617
gene id: 32536:LOC106979617
uniprot id: A0A6I9ZZM5
uniprot id: A0A6J1Y6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lambda interferon family.
messages: Secreted

32536:FAM120B
gene id: 32536:FAM120B
uniprot id: A0A6I9ZUQ7
uniprot id: A0A6I9ZY69
uniprot id: A0A6I9ZZ53
uniprot id: A0A6I9ZZ84
uniprot id: A0A6J1Z404
uniprot id: A0A6J1Z409
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

32536:GBA2
gene id: 32536:GBA2
uniprot id: A0A6J1XRV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

32536:PIK3C3
gene id: 32536:PIK3C3
uniprot id: A0A6J2A4F3
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:CORO2B
gene id: 32536:CORO2B
uniprot id: A0A6J2A0U0
uniprot id: A0A6J2A3V9
names: Similarity
messages: Belongs to the WD repeat coronin family.

32536:LOC106977870
gene id: 32536:LOC106977870
uniprot id: A0A6J1Y7L2
uniprot id: A0A6J1Y8M4
names: Similarity
messages: Belongs to the MS4A family.

32536:LOC106966139
gene id: 32536:LOC106966139
uniprot id: A0A6I9ZBS9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106986468
gene id: 32536:LOC106986468
uniprot id: A0A6J0A7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CPSF3
gene id: 32536:CPSF3
uniprot id: A0A6J0A0T3
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106974890
gene id: 32536:LOC106974890
uniprot id: A0A6I9ZNZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NSUN3
gene id: 32536:NSUN3
uniprot id: A0A6J0A3Y5
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

32536:GLMP
gene id: 32536:GLMP
uniprot id: A0A6J0A359
uniprot id: A0A6J1YGS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GLMP family.
messages: Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stability and lysosomal localization of MFSD1.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

32536:COL4A3
gene id: 32536:COL4A3
uniprot id: A0A6J1YIV4
uniprot id: A0A6J1YK96
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

32536:ATP6V1B2
gene id: 32536:ATP6V1B2
uniprot id: A0A6I9ZPK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

32536:TPI1
gene id: 32536:TPI1
uniprot id: A0A6J2AIY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

32536:GLG1
gene id: 32536:GLG1
uniprot id: A0A6J0AAM3
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

32536:PKN1
gene id: 32536:PKN1
uniprot id: A0A6J1YNE1
uniprot id: A0A6J1YNQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

32536:LOC106976615
gene id: 32536:LOC106976615
uniprot id: A0A6I9ZRI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106976558
gene id: 32536:LOC106976558
uniprot id: A0A6I9ZW03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:IZUMO4
gene id: 32536:IZUMO4
uniprot id: A0A6J1YKU9
uniprot id: A0A6J1YLN0
names: Similarity
messages: Belongs to the Izumo family.

32536:MARK1
gene id: 32536:MARK1
uniprot id: A0A6J2ALU2
uniprot id: A0A6J2AQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

32536:CILP2
gene id: 32536:CILP2
uniprot id: A0A6J1XPC0
names: Subcellular Location Annotation
messages: extracellular matrix

32536:SEC22C
gene id: 32536:SEC22C
uniprot id: A0A6J1XW17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

32536:SMIM14
gene id: 32536:SMIM14
uniprot id: A0A6J1Z542
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

32536:NCK2
gene id: 32536:NCK2
uniprot id: A0A6J2A6P4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

32536:CLASP2
gene id: 32536:CLASP2
uniprot id: A0A6J1XUU1
uniprot id: A0A6J1XVB1
uniprot id: A0A6J1XVE3
uniprot id: A0A6J1XVF3
names: Subcellular Location Annotation
messages: kinetochore

32536:ONECUT1
gene id: 32536:ONECUT1
uniprot id: A0A6I9ZEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

32536:HDC
gene id: 32536:HDC
uniprot id: A0A6I9ZEW1
uniprot id: A0A6I9ZI33
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

32536:CSRNP2
gene id: 32536:CSRNP2
uniprot id: A0A6I9ZGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

32536:ELF5
gene id: 32536:ELF5
uniprot id: A0A6I9ZWL3
uniprot id: A0A6J2AH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:ZP3
gene id: 32536:ZP3
uniprot id: A0A6J0A219
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

32536:CCNO
gene id: 32536:CCNO
uniprot id: A0A6J1XYS3
names: Similarity
messages: Belongs to the cyclin family.

32536:CALHM1
gene id: 32536:CALHM1
uniprot id: A0A6I9ZFX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

32536:RANGRF
gene id: 32536:RANGRF
uniprot id: A0A6J1YEV1
uniprot id: A0A6J1YEV4
uniprot id: A0A6J1YGY8
names: Similarity
messages: Belongs to the MOG1 family.

32536:ATP8A1
gene id: 32536:ATP8A1
uniprot id: A0A6J0A4A2
uniprot id: A0A6J0A7Z1
uniprot id: A0A6J1Z3T0
uniprot id: A0A6J1Z3T9
uniprot id: A0A6J1Z4U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

32536:MRPS30
gene id: 32536:MRPS30
uniprot id: A0A6J2AUY0
names: Subcellular Location Annotation
messages: Mitochondrion

32536:MFSD4B
gene id: 32536:MFSD4B
uniprot id: A0A6I9ZKF9
names: Subcellular Location Annotation
messages: Membrane

32536:TMLHE
gene id: 32536:TMLHE
uniprot id: A0A6J1YUW1
uniprot id: A0A6J1YWQ3
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

32536:LHFPL2
gene id: 32536:LHFPL2
uniprot id: A0A6I9ZTJ9
names: Subcellular Location Annotation
messages: Membrane

32536:PAX9
gene id: 32536:PAX9
uniprot id: A0A6J1ZV01
names: Subcellular Location Annotation
messages: Nucleus

32536:SCT
gene id: 32536:SCT
uniprot id: A0A6J1YRL8
names: Similarity
messages: Belongs to the glucagon family.

32536:TAFA4
gene id: 32536:TAFA4
uniprot id: A0A6J1XRC6
names: Similarity
messages: Belongs to the TAFA family.

32536:L3MBTL3
gene id: 32536:L3MBTL3
uniprot id: A0A6I9ZV34
uniprot id: A0A6J1Z5E9
uniprot id: A0A6J1Z6R4
uniprot id: A0A6J1Z7F4
names: Subcellular Location Annotation
messages: Nucleus

32536:ENTR1
gene id: 32536:ENTR1
uniprot id: A0A6J1YQU9
uniprot id: A0A6J1YU05
names: Similarity
messages: Belongs to the ENTR1 family.

32536:TMCO4
gene id: 32536:TMCO4
uniprot id: A0A6J1ZEZ4
uniprot id: A0A6J1ZG47
uniprot id: A0A6J1ZIB1
names: Subcellular Location Annotation
messages: Membrane

32536:THUMPD3
gene id: 32536:THUMPD3
uniprot id: A0A6J1Y1I8
names: Similarity
messages: Belongs to the methyltransferase superfamily.

32536:SESN3
gene id: 32536:SESN3
uniprot id: A0A6J1XTS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

32536:EVX1
gene id: 32536:EVX1
uniprot id: A0A6J2ANK8
names: Subcellular Location Annotation
messages: Nucleus

32536:TPK1
gene id: 32536:TPK1
uniprot id: A0A6J2ASX8
uniprot id: A0A6J2ASY3
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

32536:TRPC1
gene id: 32536:TRPC1
uniprot id: A0A6J0A3U3
uniprot id: A0A6J1ZIZ1
uniprot id: A0A6J1ZIZ6
uniprot id: A0A6J1ZK87
uniprot id: A0A6J1ZK92
uniprot id: A0A6J1ZLD2
uniprot id: A0A6J1ZMN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

32536:MDGA1
gene id: 32536:MDGA1
uniprot id: A0A6J1Z7Y9
uniprot id: A0A6J1Z9A5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:CAMK4
gene id: 32536:CAMK4
uniprot id: A0A6I9ZTM8
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:NOX1
gene id: 32536:NOX1
uniprot id: A0A6J1YYT8
names: Subcellular Location Annotation
messages: Membrane

32536:MPC1
gene id: 32536:MPC1
uniprot id: A0A6J1Z476
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

32536:ACADVL
gene id: 32536:ACADVL
uniprot id: A0A6J1YE49
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

32536:SLC4A1
gene id: 32536:SLC4A1
uniprot id: A0A6J1YI21
uniprot id: A0A6J1YI30
uniprot id: A0A6J1YKC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Membrane

32536:CRELD1
gene id: 32536:CRELD1
uniprot id: A0A6I9ZKS7
uniprot id: A0A6J1Y1P9
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PTGDR2
gene id: 32536:PTGDR2
uniprot id: A0A6J1Y756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

32536:KCNK9
gene id: 32536:KCNK9
uniprot id: A0A6J1ZQ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

32536:CETN2
gene id: 32536:CETN2
uniprot id: A0A6I9ZJ15
names: Similarity
messages: Belongs to the centrin family.

32536:MED31
gene id: 32536:MED31
uniprot id: A0A6J1YF20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

32536:STK11
gene id: 32536:STK11
uniprot id: A0A6J1YJM3
uniprot id: A0A6J1YKL7
uniprot id: A0A6J1YM45
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

32536:HEPHL1
gene id: 32536:HEPHL1
uniprot id: A0A6J0A8Q1
names: Similarity
messages: Belongs to the multicopper oxidase family.

32536:XKR8
gene id: 32536:XKR8
uniprot id: A0A6J1ZGB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

32536:NKX2-1
gene id: 32536:NKX2-1
uniprot id: A0A6J1ZW97
names: Subcellular Location Annotation
messages: Nucleus

32536:MRPL15
gene id: 32536:MRPL15
uniprot id: A0A6I9ZMZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

32536:POLR3GL
gene id: 32536:POLR3GL
uniprot id: A0A6J1YQ56
uniprot id: A0A6J1YRJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

32536:CRYAA
gene id: 32536:CRYAA
uniprot id: A0A6J1XXW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

32536:HNRNPF
gene id: 32536:HNRNPF
uniprot id: A0A6J1ZQC5
names: Subcellular Location Annotation
messages: nucleoplasm

32536:MCM2
gene id: 32536:MCM2
uniprot id: A0A6J0A7U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

32536:MAB21L1
gene id: 32536:MAB21L1
uniprot id: A0A6I9ZP83
names: Similarity
messages: Belongs to the mab-21 family.

32536:THAP1
gene id: 32536:THAP1
uniprot id: A0A6J0A979
uniprot id: A0A6J0ABV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THAP1 family.
messages: DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes.
messages: Interacts with PAWR. Component of a THAP1/THAP3-HCFC1-OGT complex that contains, either THAP1 or THAP3, HCFC1 and OGT. Interacts with OGT. Interacts (via the HBM) with HCFC1 (via the Kelch-repeat domain); the interaction recruits HCFC1 to the RRM1 promoter.
messages: nucleoplasm

32536:RND3
gene id: 32536:RND3
uniprot id: A0A6J0AA93
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

32536:WASHC3
gene id: 32536:WASHC3
uniprot id: A0A6I9ZK03
uniprot id: A0A6I9ZLK4
names: Similarity
messages: Belongs to the CCDC53 family.

32536:TUB
gene id: 32536:TUB
uniprot id: A0A6J2AHY7
uniprot id: A0A6J2AKG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

32536:SOD3
gene id: 32536:SOD3
uniprot id: A0A6J1YFC2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

32536:VAX2
gene id: 32536:VAX2
uniprot id: A0A6J2ADP1
names: Subcellular Location Annotation
messages: Nucleus

32536:DIO2
gene id: 32536:DIO2
uniprot id: A0A6J0A4H3
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

32536:CMPK1
gene id: 32536:CMPK1
uniprot id: A0A6J1ZBZ4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

32536:ATP1B1
gene id: 32536:ATP1B1
uniprot id: A0A6J1YCQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

32536:DGKD
gene id: 32536:DGKD
uniprot id: A0A6J1YDM1
uniprot id: A0A6J1YDM6
uniprot id: A0A6J1YFQ4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

32536:TMEM86A
gene id: 32536:TMEM86A
uniprot id: A0A6J2AG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

32536:PANX3
gene id: 32536:PANX3
uniprot id: A0A6I9ZRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

32536:ALX1
gene id: 32536:ALX1
uniprot id: A0A6I9ZUU7
names: Subcellular Location Annotation
messages: Nucleus

32536:DNMT3A
gene id: 32536:DNMT3A
uniprot id: A0A6J1X719
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

32536:OBP2B
gene id: 32536:OBP2B
uniprot id: A0A6J1YSC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

32536:PDE4D
gene id: 32536:PDE4D
uniprot id: A0A6I9ZR92
uniprot id: A0A6I9ZSK9
uniprot id: A0A6J1XXB4
uniprot id: A0A6J1XXF6
uniprot id: A0A6J1XXG5
uniprot id: A0A6J1XYC1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:REEP4
gene id: 32536:REEP4
uniprot id: A0A6J0A1N5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:AP3M1
gene id: 32536:AP3M1
uniprot id: A0A6J1ZLZ3
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

32536:CRYBB3
gene id: 32536:CRYBB3
uniprot id: A0A6J0A3W4
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:CPNE5
gene id: 32536:CPNE5
uniprot id: A0A6J1Z9C7
uniprot id: A0A6J1ZA74
uniprot id: A0A6J1ZBK1
names: Similarity
messages: Belongs to the copine family.

32536:PHOSPHO1
gene id: 32536:PHOSPHO1
uniprot id: A0A6J1XBG9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

32536:BOLA3
gene id: 32536:BOLA3
uniprot id: A0A6J2AHE7
names: Similarity
messages: Belongs to the BolA/IbaG family.

32536:PLEKHA8
gene id: 32536:PLEKHA8
uniprot id: A0A6J2AMC6
names: Subcellular Location Annotation
messages: trans-Golgi network membrane

32536:ERBB3
gene id: 32536:ERBB3
uniprot id: A0A6J2ABU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

32536:CDPF1
gene id: 32536:CDPF1
uniprot id: A0A6J2ACZ6
names: Similarity
messages: Belongs to the CDPF1 family.

32536:TRIM36
gene id: 32536:TRIM36
uniprot id: A0A6J2AVZ2
names: Subcellular Location Annotation
messages: cytoskeleton

32536:KYNU
gene id: 32536:KYNU
uniprot id: A0A6I9ZCS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:HAPSTR2
gene id: 32536:HAPSTR2
uniprot id: A0A6J1YZI1
names: Subcellular Location Annotation
messages: Nucleus

32536:OGFR
gene id: 32536:OGFR
uniprot id: A0A6J1YBJ8
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

32536:CHSY1
gene id: 32536:CHSY1
uniprot id: A0A6J2A5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

32536:CRKL
gene id: 32536:CRKL
uniprot id: A0A6J0ABS7
names: Similarity
messages: Belongs to the CRK family.

32536:TMEM30A
gene id: 32536:TMEM30A
uniprot id: A0A6J0A173
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

32536:LOC106976801
gene id: 32536:LOC106976801
uniprot id: A0A6J1Z7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEG1 family.
messages: Secreted

32536:PARN
gene id: 32536:PARN
uniprot id: A0A6I9ZJT2
uniprot id: A0A6J1Y2U8
uniprot id: A0A6J1Y3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm

32536:RPL22L1
gene id: 32536:RPL22L1
uniprot id: A0A6J0A9A0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

32536:VTI1B
gene id: 32536:VTI1B
uniprot id: A0A6I9ZMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

32536:SLC20A1
gene id: 32536:SLC20A1
uniprot id: A0A6J1XAP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

32536:STX2
gene id: 32536:STX2
uniprot id: A0A6J1Y5H1
uniprot id: A0A6J1Y769
names: Similarity
messages: Belongs to the syntaxin family.

32536:SERPINB1
gene id: 32536:SERPINB1
uniprot id: A0A6J1XUA3
names: Similarity
messages: Belongs to the serpin family.

32536:PSIP1
gene id: 32536:PSIP1
uniprot id: A0A6J1YD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

32536:NCF2
gene id: 32536:NCF2
uniprot id: A0A6J2AK50
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

32536:ZDHHC17
gene id: 32536:ZDHHC17
uniprot id: A0A6I9ZGL3
uniprot id: A0A6I9ZIB5
uniprot id: A0A6J2AF45
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:LOC106966287
gene id: 32536:LOC106966287
uniprot id: A0A6J1XEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

32536:ITGA7
gene id: 32536:ITGA7
uniprot id: A0A6J2ABP1
uniprot id: A0A6J2ABY6
uniprot id: A0A6J2ACW8
uniprot id: A0A6J2AFL7
uniprot id: A0A6J2AG31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

32536:SIX1
gene id: 32536:SIX1
uniprot id: A0A6I9ZNG6
names: Subcellular Location Annotation
messages: Nucleus

32536:TAAR9
gene id: 32536:TAAR9
uniprot id: A0A6I9ZTD1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:PADI2
gene id: 32536:PADI2
uniprot id: A0A6J1ZIH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

32536:IFI30
gene id: 32536:IFI30
uniprot id: A0A6J1XNS0
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

32536:RPLP0
gene id: 32536:RPLP0
uniprot id: A0A6I9ZQ55
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

32536:CACUL1
gene id: 32536:CACUL1
uniprot id: A0A6I9ZGJ5
names: Similarity
messages: Belongs to the cullin family.

32536:KCNJ15
gene id: 32536:KCNJ15
uniprot id: A0A6I9ZCZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

32536:SLC48A1
gene id: 32536:SLC48A1
uniprot id: A0A6J1XH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRG family.
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

32536:PPP2R2A
gene id: 32536:PPP2R2A
uniprot id: A0A6J2AXG2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

32536:LOC106986813
gene id: 32536:LOC106986813
uniprot id: A0A0A0Y2D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:YKT6
gene id: 32536:YKT6
uniprot id: A0A6J1Y9W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

32536:MMACHC
gene id: 32536:MMACHC
uniprot id: A0A6I9ZM86
names: Similarity
messages: Belongs to the MMACHC family.

32536:FKTN
gene id: 32536:FKTN
uniprot id: A0A6J1XDL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LicD transferase family.
messages: Golgi apparatus membrane

32536:PHGDH
gene id: 32536:PHGDH
uniprot id: A0A6I9ZYY0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

32536:LOC106987131
gene id: 32536:LOC106987131
uniprot id: A0A6J0A5X1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RPL37A
gene id: 32536:RPL37A
uniprot id: A0A6I9ZMF9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

32536:HSPA8
gene id: 32536:HSPA8
uniprot id: A0A6J1XJH3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

32536:BCKDK
gene id: 32536:BCKDK
uniprot id: A0A6J1YQB4
uniprot id: A0A6J1YQB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

32536:PTGES3L
gene id: 32536:PTGES3L
uniprot id: A0A6J1YK27
uniprot id: A0A6J1YKV6
names: Similarity
messages: Belongs to the p23/wos2 family.

32536:TRNT1
gene id: 32536:TRNT1
uniprot id: A0A6I9ZI41
uniprot id: A0A6I9ZL76
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

32536:LOC106982042
gene id: 32536:LOC106982042
uniprot id: A0A6J1YU18
uniprot id: A0A6J1YVF5
names: Subcellular Location Annotation
messages: Membrane

32536:SF3B3
gene id: 32536:SF3B3
uniprot id: A0A6J0A1Y5
names: Subcellular Location Annotation
messages: Nucleus

32536:ARL9
gene id: 32536:ARL9
uniprot id: A0A6J1Z726
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

32536:UNC5C
gene id: 32536:UNC5C
uniprot id: A0A6J1ZIQ9
uniprot id: A0A6J1ZL13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

32536:CCDC103
gene id: 32536:CCDC103
uniprot id: A0A6J1YJC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

32536:LOC106980764
gene id: 32536:LOC106980764
uniprot id: A0A6J2ANQ2
uniprot id: A0A6J2ASW8
names: Similarity
messages: Belongs to the TCAF family.

32536:MINDY4
gene id: 32536:MINDY4
uniprot id: A0A6J2AME4
uniprot id: A0A6J2AR28
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

32536:ERLIN1
gene id: 32536:ERLIN1
uniprot id: A0A6J1ZMB3
uniprot id: A0A6J1ZMK8
uniprot id: A0A6J1ZNF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

32536:PARVA
gene id: 32536:PARVA
uniprot id: A0A6J2AG38
uniprot id: A0A6J2AHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane

32536:SENP2
gene id: 32536:SENP2
uniprot id: A0A6J1ZI54
uniprot id: A0A6J1ZJ21
uniprot id: A0A6J1ZK74
names: Similarity
messages: Belongs to the peptidase C48 family.

32536:SUPT4H1
gene id: 32536:SUPT4H1
uniprot id: A0A6J0A934
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

32536:DDX4
gene id: 32536:DDX4
uniprot id: A0A6I9ZUV7
uniprot id: A0A6J1XYE3
uniprot id: A0A6J1XYG2
uniprot id: A0A6J1XYH6
uniprot id: A0A6J1XYV6
uniprot id: A0A6J1XZF1
uniprot id: A0A6J1XZG8
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:NR1I3
gene id: 32536:NR1I3
uniprot id: A0A6J1YHC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:MTRF1
gene id: 32536:MTRF1
uniprot id: A0A6I9ZT10
uniprot id: A0A6I9ZWL7
uniprot id: A0A6J1ZTK6
uniprot id: A0A6J1ZX91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

32536:HOXD1
gene id: 32536:HOXD1
uniprot id: A0A6J1Z4Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

32536:GPR101
gene id: 32536:GPR101
uniprot id: A0A6J1YZE5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:TGFB2
gene id: 32536:TGFB2
uniprot id: A0A6I9ZZF6
uniprot id: A0A6J0A0E0
uniprot id: A0A6J2AQX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

32536:LOC106980755
gene id: 32536:LOC106980755
uniprot id: A0A6J0A164
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:BEST1
gene id: 32536:BEST1
uniprot id: A0A6J1YB28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion channel-forming bestrophin (TC 1.A.46) family. Calcium-sensitive chloride channel subfamily.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

32536:IFT43
gene id: 32536:IFT43
uniprot id: A0A6I9ZSZ1
names: Similarity
messages: Belongs to the IFT43 family.

32536:LOC106983294
gene id: 32536:LOC106983294
uniprot id: A0A6J0A410
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Cell membrane
messages: Membrane

32536:MINAR2
gene id: 32536:MINAR2
uniprot id: A0A6I9ZLE9
names: Similarity
messages: Belongs to the MINAR family.

32536:HSD17B6
gene id: 32536:HSD17B6
uniprot id: A0A6J0A8A2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:UBN1
gene id: 32536:UBN1
uniprot id: A0A6I9ZW58
uniprot id: A0A6I9ZZE8
names: Similarity
messages: Belongs to the ubinuclein family.

32536:SEC61A2
gene id: 32536:SEC61A2
uniprot id: A0A6J2ALD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:CLPS
gene id: 32536:CLPS
uniprot id: A0A6I9ZQS5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

32536:STAC
gene id: 32536:STAC
uniprot id: A0A6J1XV07
uniprot id: A0A6J1XVC9
names: Subcellular Location Annotation
messages: sarcolemma

32536:PGM2
gene id: 32536:PGM2
uniprot id: A0A6J1YXC2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

32536:CSN1S1
gene id: 32536:CSN1S1
uniprot id: A0A6I9ZVM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Secreted

32536:UBE2N
gene id: 32536:UBE2N
uniprot id: A0A6J2AEV3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:MEIS2
gene id: 32536:MEIS2
uniprot id: A0A6J1ZYN9
uniprot id: A0A6J1ZZ18
uniprot id: A0A6J1ZZU0
uniprot id: A0A6J2A1P5
uniprot id: A0A6J2A2T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

32536:FAM110C
gene id: 32536:FAM110C
uniprot id: A0A6J2AUJ6
names: Similarity
messages: Belongs to the FAM110 family.

32536:INHBE
gene id: 32536:INHBE
uniprot id: A0A6J2ACK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

32536:CDH20
gene id: 32536:CDH20
uniprot id: A0A6J2A525
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:LOC106989476
gene id: 32536:LOC106989476
uniprot id: A0A6J1YLX4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PLP2
gene id: 32536:PLP2
uniprot id: A0A6J1YX11
names: Subcellular Location Annotation
messages: Membrane

32536:OLFM3
gene id: 32536:OLFM3
uniprot id: A0A6I9ZWB2
uniprot id: A0A6J1ZD58
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

32536:GYS1
gene id: 32536:GYS1
uniprot id: A0A6J0A809
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

32536:CLDN18
gene id: 32536:CLDN18
uniprot id: A0A6I9ZRX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

32536:IL17RC
gene id: 32536:IL17RC
uniprot id: A0A6J1Y0E5
uniprot id: A0A6J1Y0F0
uniprot id: A0A6J1Y0P4
uniprot id: A0A6J1Y0Q0
uniprot id: A0A6J1Y0S7
uniprot id: A0A6J1Y0T3
uniprot id: A0A6J1Y154
uniprot id: A0A6J1Y1L8
uniprot id: A0A6J1Y1M3
names: Subcellular Location Annotation
messages: Membrane

32536:DEFB124
gene id: 32536:DEFB124
uniprot id: A0A6J2ACL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

32536:MRPL43
gene id: 32536:MRPL43
uniprot id: A0A6I9ZHD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

32536:COQ6
gene id: 32536:COQ6
uniprot id: A0A6I9ZT25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Cell projection
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ7.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Golgi apparatus
messages: Mitochondrion inner membrane

32536:ANO10
gene id: 32536:ANO10
uniprot id: A0A6J1XUQ9
uniprot id: A0A6J1XUS0
uniprot id: A0A6J1XV32
uniprot id: A0A6J1XV89
uniprot id: A0A6J1XV96
uniprot id: A0A6J1XVD3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:SLC2A4
gene id: 32536:SLC2A4
uniprot id: A0A6J1YEX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Membrane
messages: perinuclear region

32536:FOXD3
gene id: 32536:FOXD3
uniprot id: A0A6J1ZCN0
names: Subcellular Location Annotation
messages: Nucleus

32536:MAP3K9
gene id: 32536:MAP3K9
uniprot id: A0A6J1ZXJ6
uniprot id: A0A6J1ZZ50
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

32536:SRPRA
gene id: 32536:SRPRA
uniprot id: A0A6I9ZTS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:THRAP3
gene id: 32536:THRAP3
uniprot id: A0A6J1ZEG8
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

32536:SIAH1
gene id: 32536:SIAH1
uniprot id: A0A6J0A6S7
uniprot id: A0A6J1Y6D8
uniprot id: A0A6J1Y7B6
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

32536:ICOS
gene id: 32536:ICOS
uniprot id: A0A6I9ZWP9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

32536:RFLNB
gene id: 32536:RFLNB
uniprot id: A0A6J1XD64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

32536:ELP4
gene id: 32536:ELP4
uniprot id: A0A6I9ZJB0
uniprot id: A0A6I9ZMT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

32536:ADAM21
gene id: 32536:ADAM21
uniprot id: A0A6I9ZQ16
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TBR1
gene id: 32536:TBR1
uniprot id: A0A6J1Z3W3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:WNT8A
gene id: 32536:WNT8A
uniprot id: A0A6I9ZJX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

32536:TK2
gene id: 32536:TK2
uniprot id: A0A6I9ZNK1
uniprot id: A0A6I9ZP76
uniprot id: A0A6J2ATK8
names: Similarity
messages: Belongs to the DCK/DGK family.

32536:SF3B5
gene id: 32536:SF3B5
uniprot id: A0A6I9ZFU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

32536:RPL11
gene id: 32536:RPL11
uniprot id: A0A6I9ZSZ0
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

32536:KCNK4
gene id: 32536:KCNK4
uniprot id: A0A6J1Y8B7
uniprot id: A0A6J1Y8D6
uniprot id: A0A6J1YA74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:CMTM8
gene id: 32536:CMTM8
uniprot id: A0A6J1XVN6
uniprot id: A0A6J1XVP0
names: Subcellular Location Annotation
messages: Membrane

32536:DOLK
gene id: 32536:DOLK
uniprot id: A0A6J1XF77
names: Similarity
messages: Belongs to the polyprenol kinase family.

32536:SLC24A5
gene id: 32536:SLC24A5
uniprot id: A0A6I9ZGC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

32536:WRNIP1
gene id: 32536:WRNIP1
uniprot id: A0A6I9ZS98
uniprot id: A0A6J1XU35
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

32536:BCLAF3
gene id: 32536:BCLAF3
uniprot id: A0A6J1YZ87
uniprot id: A0A6J1Z0E5
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

32536:PPP3CA
gene id: 32536:PPP3CA
uniprot id: A0A6J1ZIH4
uniprot id: A0A6J1ZJR6
uniprot id: A0A6J1ZJS1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

32536:TACSTD2
gene id: 32536:TACSTD2
uniprot id: A0A6J1ZC59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:SLC27A6
gene id: 32536:SLC27A6
uniprot id: A0A6J2ATC0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:STC1
gene id: 32536:STC1
uniprot id: A0A6I9ZDM3
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

32536:SHQ1
gene id: 32536:SHQ1
uniprot id: A0A6I9ZGP8
names: Similarity
messages: Belongs to the SHQ1 family.

32536:LUC7L3
gene id: 32536:LUC7L3
uniprot id: A0A6J1XBQ7
uniprot id: A0A6J1XBQ9
uniprot id: A0A6J1XBR8
uniprot id: A0A6J1XBS0
uniprot id: A0A6J1XBS3
names: Similarity
messages: Belongs to the Luc7 family.

32536:LOC106986483
gene id: 32536:LOC106986483
uniprot id: A0A6J0A504
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC128310914
gene id: 32536:LOC128310914
uniprot id: A0A6I9ZC01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

32536:CDV3
gene id: 32536:CDV3
uniprot id: A0A6J1ZJD3
uniprot id: A0A6J1ZJD7
uniprot id: A0A6J1ZJQ8
uniprot id: A0A6J1ZKL2
uniprot id: A0A6J1ZLS0
uniprot id: A0A6J1ZLS5
uniprot id: A0A6J1ZN28
uniprot id: A0A6J1ZN33
names: Similarity
messages: Belongs to the CDV3 family.

32536:NPBWR1
gene id: 32536:NPBWR1
uniprot id: A0A6J1Y2E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:DR1
gene id: 32536:DR1
uniprot id: A0A6I9ZJK6
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

32536:SNTG2
gene id: 32536:SNTG2
uniprot id: A0A6J2AU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

32536:MYO1B
gene id: 32536:MYO1B
uniprot id: A0A6J1YYF9
uniprot id: A0A6J1YYI0
uniprot id: A0A6J1YYK1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

32536:GCLM
gene id: 32536:GCLM
uniprot id: A0A6J1Z9Z5
uniprot id: A0A6J1ZAV2
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

32536:CCDC149
gene id: 32536:CCDC149
uniprot id: A0A6J1YGK5
names: Similarity
messages: Belongs to the CCDC149 family.

32536:SLC44A2
gene id: 32536:SLC44A2
uniprot id: A0A6J1YMN4
uniprot id: A0A6J1YMP0
uniprot id: A0A6J1YPC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

32536:LOC113596888
gene id: 32536:LOC113596888
uniprot id: A0A6J1YUF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GHRH
gene id: 32536:GHRH
uniprot id: A0A6J2A7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

32536:PDZK1IP1
gene id: 32536:PDZK1IP1
uniprot id: A0A6I9ZRT4
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106986225
gene id: 32536:LOC106986225
uniprot id: A0A6J0A4P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GALNT10
gene id: 32536:GALNT10
uniprot id: A0A6J2AU18
uniprot id: A0A6J2AVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:KRT17
gene id: 32536:KRT17
uniprot id: A0A6J1YIT6
names: Similarity
messages: Belongs to the intermediate filament family.

32536:CPLX4
gene id: 32536:CPLX4
uniprot id: A0A6I9ZYG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

32536:MLLT3
gene id: 32536:MLLT3
uniprot id: A0A6J1YDV6
uniprot id: A0A6J1YF70
names: Subcellular Location Annotation
messages: Nucleus

32536:MRI1
gene id: 32536:MRI1
uniprot id: A0A6J1YNG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

32536:LOC106987347
gene id: 32536:LOC106987347
uniprot id: A0A6J0A9Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LIPC
gene id: 32536:LIPC
uniprot id: A0A6J2A438
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:ENTREP1
gene id: 32536:ENTREP1
uniprot id: A0A6J0A457
names: Similarity
messages: Belongs to the ENTREP family.

32536:ABHD14A
gene id: 32536:ABHD14A
uniprot id: A0A6J1XQ60
uniprot id: A0A6J1XQD4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cytoplasm

32536:LOC106987509
gene id: 32536:LOC106987509
uniprot id: A0A6J0A951
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Membrane
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

32536:TRADD
gene id: 32536:TRADD
uniprot id: A0A6J2ATB8
names: Subcellular Location Annotation
messages: Nucleus
messages: cytoskeleton

32536:USP21
gene id: 32536:USP21
uniprot id: A0A6J1YH55
uniprot id: A0A6J1YIM5
uniprot id: A0A6J1YJD6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:NRM
gene id: 32536:NRM
uniprot id: A0A6I9ZDR4
uniprot id: A0A6I9ZGW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

32536:LTB4R
gene id: 32536:LTB4R
uniprot id: A0A6J1ZV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

32536:EML5
gene id: 32536:EML5
uniprot id: A0A6J2A025
uniprot id: A0A6J2A1A1
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

32536:LOC106979025
gene id: 32536:LOC106979025
uniprot id: A0A6I9ZV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ATP6V1G1
gene id: 32536:ATP6V1G1
uniprot id: A0A6I9ZZ16
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

32536:RPL10
gene id: 32536:RPL10
uniprot id: A0A6J0A9X4
uniprot id: A0A6J1YWV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

32536:CDC73
gene id: 32536:CDC73
uniprot id: A0A6J2AQA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

32536:DIPK1A
gene id: 32536:DIPK1A
uniprot id: A0A6J1ZA15
names: Similarity
messages: Belongs to the DIPK family.

32536:ACAT2
gene id: 32536:ACAT2
uniprot id: A0A6J1Z4L6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

32536:STAMBPL1
gene id: 32536:STAMBPL1
uniprot id: A0A6J1YKN9
names: Similarity
messages: Belongs to the peptidase M67C family.

32536:TIRAP
gene id: 32536:TIRAP
uniprot id: A0A6J1XJL9
uniprot id: A0A6J1XJQ2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane

32536:ZAR1L
gene id: 32536:ZAR1L
uniprot id: A0A6I9ZT11
uniprot id: A0A6J1ZV10
names: Similarity
names: Subunit
messages: Belongs to the ZAR1 family.
messages: Interacts with YBX2.

32536:LOC106982720
gene id: 32536:LOC106982720
uniprot id: A0A6J0A3F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:OAZ3
gene id: 32536:OAZ3
uniprot id: A0A6J1Z3B1
names: Similarity
messages: Belongs to the ODC antizyme family.

32536:ATP6V1C2
gene id: 32536:ATP6V1C2
uniprot id: A0A6J2AUG9
uniprot id: A0A6J2AUH4
uniprot id: A0A6J2AUX2
uniprot id: A0A6J2AWN9
uniprot id: A0A6J2AZ29
uniprot id: A0A6J2AZT5
uniprot id: A0A6J2AZU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

32536:BIVM
gene id: 32536:BIVM
uniprot id: A0A6J0A493
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

32536:TSPYL5
gene id: 32536:TSPYL5
uniprot id: A0A6J1ZV40
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

32536:ICAM4
gene id: 32536:ICAM4
uniprot id: A0A6J1YM89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

32536:LOC106969861
gene id: 32536:LOC106969861
uniprot id: A0A6I9ZH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SERPINA3
gene id: 32536:SERPINA3
uniprot id: A0A6I9ZWD8
names: Similarity
messages: Belongs to the serpin family.

32536:TXNL4B
gene id: 32536:TXNL4B
uniprot id: A0A6J0ACP8
uniprot id: A0A6J2APJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

32536:ILF3
gene id: 32536:ILF3
uniprot id: A0A6J1YM55
uniprot id: A0A6J1YM57
uniprot id: A0A6J1YNS6
uniprot id: A0A6J1YQ06
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:HRH2
gene id: 32536:HRH2
uniprot id: A0A6J1XDX1
uniprot id: A0A6J1XDX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:ELP3
gene id: 32536:ELP3
uniprot id: A0A6J0A913
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

32536:VIM
gene id: 32536:VIM
uniprot id: A0A6J2AIW4
names: Similarity
messages: Belongs to the intermediate filament family.

32536:YWHAZ
gene id: 32536:YWHAZ
uniprot id: A0A6J1ZUX6
names: Similarity
messages: Belongs to the 14-3-3 family.

32536:ZRANB1
gene id: 32536:ZRANB1
uniprot id: A0A6I9ZJT6
uniprot id: A0A6J1ZR95
names: Similarity
messages: Belongs to the peptidase C64 family.

32536:DEUP1
gene id: 32536:DEUP1
uniprot id: A0A6J1XTB7
names: Similarity
messages: Belongs to the CEP63 family.

32536:ENTPD8
gene id: 32536:ENTPD8
uniprot id: A0A6J0A8J2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

32536:GOLPH3L
gene id: 32536:GOLPH3L
uniprot id: A0A6I9ZWT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

32536:ADAM32
gene id: 32536:ADAM32
uniprot id: A0A6I9ZYS3
uniprot id: A0A6J2AEF4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:NLGN3
gene id: 32536:NLGN3
uniprot id: A0A6J0A3Z8
uniprot id: A0A6J1YW11
uniprot id: A0A6J1YY11
uniprot id: A0A6J1YZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

32536:SLC25A35
gene id: 32536:SLC25A35
uniprot id: A0A6I9ZME5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:ABCA9
gene id: 32536:ABCA9
uniprot id: A0A6I9ZUF6
names: Subcellular Location Annotation
messages: Membrane

32536:CDH9
gene id: 32536:CDH9
uniprot id: A0A6J0A5P8
uniprot id: A0A6J2AL85
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:ADI1
gene id: 32536:ADI1
uniprot id: A0A6J2AWC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer. Interacts with MMP14.
messages: Nucleus

32536:FUT9
gene id: 32536:FUT9
uniprot id: A0A6J1Z6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

32536:KCNA3
gene id: 32536:KCNA3
uniprot id: A0A6I9ZV56
names: Subcellular Location Annotation
messages: Membrane

32536:SLC28A3
gene id: 32536:SLC28A3
uniprot id: A0A6I9ZVU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

32536:PANX1
gene id: 32536:PANX1
uniprot id: A0A6J0A8G9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

32536:KIFBP
gene id: 32536:KIFBP
uniprot id: A0A6I9ZER3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

32536:GATA3
gene id: 32536:GATA3
uniprot id: A0A6J2AGV4
uniprot id: A0A6J2AH96
names: Subcellular Location Annotation
messages: Nucleus

32536:CNOT2
gene id: 32536:CNOT2
uniprot id: A0A6J2AEU1
uniprot id: A0A6J2AFA4
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

32536:ASIC4
gene id: 32536:ASIC4
uniprot id: A0A6J1YKE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

32536:GCG
gene id: 32536:GCG
uniprot id: A0A6J0A5J6
uniprot id: A0A6J1Z1T9
names: Similarity
messages: Belongs to the glucagon family.

32536:CDCA7
gene id: 32536:CDCA7
uniprot id: A0A6J0A9R6
uniprot id: A0A6J0AAR0
uniprot id: A0A6J1Z1N5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:HDDC2
gene id: 32536:HDDC2
uniprot id: A0A6J1Z7J6
uniprot id: A0A6J1Z8X7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

32536:STXBP5
gene id: 32536:STXBP5
uniprot id: A0A6J1Z4T6
uniprot id: A0A6J1Z534
uniprot id: A0A6J1Z6Q1
uniprot id: A0A6J1Z848
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

32536:ADPRS
gene id: 32536:ADPRS
uniprot id: A0A6J1ZDT6
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

32536:SFXN1
gene id: 32536:SFXN1
uniprot id: A0A6J1XDQ1
uniprot id: A0A6J1XDQ2
uniprot id: A0A6J1XDV1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

32536:TFE3
gene id: 32536:TFE3
uniprot id: A0A6J1YZB5
uniprot id: A0A6J1Z0J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

32536:VPS26B
gene id: 32536:VPS26B
uniprot id: A0A6I9ZSV0
names: Similarity
messages: Belongs to the VPS26 family.

32536:RABGGTB
gene id: 32536:RABGGTB
uniprot id: A0A6I9ZWG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

32536:CDR2L
gene id: 32536:CDR2L
uniprot id: A0A6J1YTX1
names: Similarity
messages: Belongs to the CDR2 family.

32536:GPR4
gene id: 32536:GPR4
uniprot id: A0A6J1XM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:SLC6A14
gene id: 32536:SLC6A14
uniprot id: A0A6I9ZH45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

32536:GPBP1
gene id: 32536:GPBP1
uniprot id: A0A6I9ZPH5
uniprot id: A0A6I9ZT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

32536:TESMIN
gene id: 32536:TESMIN
uniprot id: A0A6J1Y9K2
uniprot id: A0A6J1Y9Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

32536:LOC106988076
gene id: 32536:LOC106988076
uniprot id: A0A6J0A7D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

32536:SSBP4
gene id: 32536:SSBP4
uniprot id: A0A6J1XNV0
uniprot id: A0A6J1XNV8
uniprot id: A0A6J1XP40
uniprot id: A0A6J1XP43
uniprot id: A0A6J1XP50
names: Subcellular Location Annotation
messages: Nucleus

32536:LDLRAD4
gene id: 32536:LDLRAD4
uniprot id: A0A6J0A0M3
uniprot id: A0A6J2A320
uniprot id: A0A6J2A370
uniprot id: A0A6J2A6K2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:MMUT
gene id: 32536:MMUT
uniprot id: A0A6I9ZSG7
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

32536:LOC106979591
gene id: 32536:LOC106979591
uniprot id: A0A6J1Y671
names: Subcellular Location Annotation
messages: Nucleus

32536:ACER1
gene id: 32536:ACER1
uniprot id: A0A6I9ZRD8
uniprot id: A0A6J1YLE8
uniprot id: A0A6J1YME1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:ANAPC5
gene id: 32536:ANAPC5
uniprot id: A0A6I9ZGT1
uniprot id: A0A6J1Y481
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

32536:ZNF687
gene id: 32536:ZNF687
uniprot id: A0A6J1Z4N7
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

32536:RRAD
gene id: 32536:RRAD
uniprot id: A0A6J2AP01
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

32536:MS4A5
gene id: 32536:MS4A5
uniprot id: A0A6I9ZY66
names: Similarity
messages: Belongs to the MS4A family.

32536:NKAIN1
gene id: 32536:NKAIN1
uniprot id: A0A6J1ZE96
uniprot id: A0A6J1ZG22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:RCAN3
gene id: 32536:RCAN3
uniprot id: A0A6I9ZSY5
uniprot id: A0A6J1ZEJ1
uniprot id: A0A6J1ZFP6
names: Similarity
messages: Belongs to the RCAN family.

32536:TLCD2
gene id: 32536:TLCD2
uniprot id: A0A6J0A4Z0
names: Subcellular Location Annotation
messages: Membrane

32536:INTS10
gene id: 32536:INTS10
uniprot id: A0A6J2AG22
uniprot id: A0A6J2AGH1
uniprot id: A0A6J2AGH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 10 family.
messages: Nucleus

32536:HMGCS1
gene id: 32536:HMGCS1
uniprot id: A0A6I9ZHV7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

32536:NPL
gene id: 32536:NPL
uniprot id: A0A6I9ZFI2
uniprot id: A0A6J2AL89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Cytoplasm
messages: Homotetramer.

32536:IL17A
gene id: 32536:IL17A
uniprot id: A0A6I9ZR54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

32536:LOC106965661
gene id: 32536:LOC106965661
uniprot id: A0A6I9ZCJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:P2RY13
gene id: 32536:P2RY13
uniprot id: A0A6I9ZU69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:BPGM
gene id: 32536:BPGM
uniprot id: A0A6J2ASE5
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

32536:TBCD
gene id: 32536:TBCD
uniprot id: A0A6J1YTR8
names: Similarity
messages: Belongs to the TBCD family.

32536:ATRAID
gene id: 32536:ATRAID
uniprot id: A0A6I9ZJ40
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ACTBL2
gene id: 32536:ACTBL2
uniprot id: A0A6I9ZUB5
names: Similarity
messages: Belongs to the actin family.

32536:ABCB1
gene id: 32536:ABCB1
uniprot id: A0A6J0A972
uniprot id: A0A6J0AA96
names: Subcellular Location Annotation
messages: Membrane

32536:TAFAZZIN
gene id: 32536:TAFAZZIN
uniprot id: A0A6J1YWY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane

32536:BTF3L4
gene id: 32536:BTF3L4
uniprot id: A0A6J1ZCK3
uniprot id: A0A6J1ZF94
names: Similarity
messages: Belongs to the NAC-beta family.

32536:PSMA4
gene id: 32536:PSMA4
uniprot id: A0A6J2A308
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

32536:CBFB
gene id: 32536:CBFB
uniprot id: A0A6J2AP59
uniprot id: A0A6J2APM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

32536:TGIF1
gene id: 32536:TGIF1
uniprot id: A0A6J2A3N8
names: Subcellular Location Annotation
messages: Nucleus

32536:PNLDC1
gene id: 32536:PNLDC1
uniprot id: A0A6J1Z4B1
uniprot id: A0A6J1Z5Q4
uniprot id: A0A6J1Z695
names: Similarity
messages: Belongs to the CAF1 family.

32536:LOC106980596
gene id: 32536:LOC106980596
uniprot id: A0A6J0A1N6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

32536:RPL27
gene id: 32536:RPL27
uniprot id: A0A6I9ZRH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

32536:CKAP5
gene id: 32536:CKAP5
uniprot id: A0A6I9ZV11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TOG/XMAP215 family.
messages: kinetochore

32536:DIP2B
gene id: 32536:DIP2B
uniprot id: A0A6J1XHE3
uniprot id: A0A6J1XHG4
names: Similarity
messages: Belongs to the DIP2 family.

32536:ATG16L1
gene id: 32536:ATG16L1
uniprot id: A0A6J1YEP5
uniprot id: A0A6J1YEQ4
uniprot id: A0A6J1YFV7
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

32536:CDK5RAP2
gene id: 32536:CDK5RAP2
uniprot id: A0A6J1XE47
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: centrosome

32536:LCAT
gene id: 32536:LCAT
uniprot id: A0A6I9ZK18
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

32536:ARHGEF6
gene id: 32536:ARHGEF6
uniprot id: A0A6J1YZJ2
uniprot id: A0A6J1YZJ5
uniprot id: A0A6J1YZK1
uniprot id: A0A6J1Z0P2
names: Subcellular Location Annotation
messages: lamellipodium

32536:PNKD
gene id: 32536:PNKD
uniprot id: A0A6J1YNA8
uniprot id: A0A6J1YNF8
uniprot id: A0A6J1YPQ4
uniprot id: A0A6J1YPS0
uniprot id: A0A6J1YQ37
uniprot id: A0A6J1YRB0
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

32536:GNL2
gene id: 32536:GNL2
uniprot id: A0A6I9ZSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
messages: GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation.
messages: nucleolus

32536:WDR4
gene id: 32536:WDR4
uniprot id: A0A6J1XXK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat TRM82 family.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

32536:LOC106977867
gene id: 32536:LOC106977867
uniprot id: A0A6J1Y8I4
uniprot id: A0A6J1YAB4
names: Similarity
messages: Belongs to the MS4A family.

32536:IARS2
gene id: 32536:IARS2
uniprot id: A0A6J2AQG0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:LAMB2
gene id: 32536:LAMB2
uniprot id: A0A6I9ZZ14
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

32536:CC2H3orf70
gene id: 32536:CC2H3orf70
uniprot id: A0A6J1ZHU6
names: Similarity
messages: Belongs to the UPF0524 family.

32536:CDIPT
gene id: 32536:CDIPT
uniprot id: A0A6J1YQ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

32536:PREPL
gene id: 32536:PREPL
uniprot id: A0A6J0A354
uniprot id: A0A6J0A360
uniprot id: A0A6J2AFY0
names: Similarity
messages: Belongs to the peptidase S9A family.

32536:TEX13A
gene id: 32536:TEX13A
uniprot id: A0A6J1YVI9
names: Similarity
messages: Belongs to the TEX13 family.

32536:HAUS1
gene id: 32536:HAUS1
uniprot id: A0A6J2A5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

32536:STX19
gene id: 32536:STX19
uniprot id: A0A6J2AY48
names: Similarity
messages: Belongs to the syntaxin family.

32536:TOP1
gene id: 32536:TOP1
uniprot id: A0A6J2A8N1
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

32536:MGMT
gene id: 32536:MGMT
uniprot id: A0A6J1ZPY0
uniprot id: A0A6J1ZRG5
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

32536:SUV39H1
gene id: 32536:SUV39H1
uniprot id: A0A6J1YXF3
uniprot id: A0A6J1YYM0
uniprot id: A0A6J1YZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

32536:ARF6
gene id: 32536:ARF6
uniprot id: A0A6J1ZXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

32536:HAPLN4
gene id: 32536:HAPLN4
uniprot id: A0A6J1XP78
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:LOC106983073
gene id: 32536:LOC106983073
uniprot id: A0A6J0A174
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106987336
gene id: 32536:LOC106987336
uniprot id: A0A6J0A9X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106969339
gene id: 32536:LOC106969339
uniprot id: A0A6I9ZLD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RBBP8
gene id: 32536:RBBP8
uniprot id: A0A6J2A4U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

32536:COPZ2
gene id: 32536:COPZ2
uniprot id: A0A6J1XBA1
uniprot id: A0A6J1XBB3
uniprot id: A0A6J1XBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

32536:FAM98A
gene id: 32536:FAM98A
uniprot id: A0A6I9ZJA2
names: Similarity
messages: Belongs to the FAM98 family.

32536:LOC106987137
gene id: 32536:LOC106987137
uniprot id: A0A6J1YHG0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:OGFOD1
gene id: 32536:OGFOD1
uniprot id: A0A6I9ZLT5
uniprot id: A0A6J1Y669
names: Similarity
messages: Belongs to the TPA1 family.

32536:KLHDC3
gene id: 32536:KLHDC3
uniprot id: A0A6J1Z7M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

32536:CLEC12B
gene id: 32536:CLEC12B
uniprot id: A0A6I9ZB75
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:DKC1
gene id: 32536:DKC1
uniprot id: A0A6J1YWS2
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

32536:BBOX1
gene id: 32536:BBOX1
uniprot id: A0A6J2AFN3
names: Function
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.

32536:ITGA4
gene id: 32536:ITGA4
uniprot id: A0A6J1Z310
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

32536:LOC106988955
gene id: 32536:LOC106988955
uniprot id: A0A6J1Y6H3
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

32536:SLC52A3
gene id: 32536:SLC52A3
uniprot id: A0A6J2A6T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

32536:VAMP8
gene id: 32536:VAMP8
uniprot id: A0A6I9ZYM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

32536:NLRP3
gene id: 32536:NLRP3
uniprot id: A0A6I9ZE21
names: Similarity
messages: Belongs to the NLRP family.

32536:MPP7
gene id: 32536:MPP7
uniprot id: A0A6J2AI76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: adherens junction
messages: tight junction

32536:ATP6V1D
gene id: 32536:ATP6V1D
uniprot id: A0A6I9ZMP0
uniprot id: A0A6I9ZP59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: cilium
messages: clathrin-coated vesicle membrane

32536:MEIG1
gene id: 32536:MEIG1
uniprot id: A0A6J2AHK9
names: Function
names: Similarity
messages: Belongs to the MEIG1 family.
messages: Essential for spermiogenesis.

32536:SRRD
gene id: 32536:SRRD
uniprot id: A0A6J1YN53
names: Similarity
messages: Belongs to the SRR1 family.

32536:TIMM10
gene id: 32536:TIMM10
uniprot id: A0A6I9ZX84
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

32536:AGPAT1
gene id: 32536:AGPAT1
uniprot id: A0A6J1Z9F9
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

32536:RGS2
gene id: 32536:RGS2
uniprot id: A0A6J2ALQ1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: nucleolus

32536:RHBG
gene id: 32536:RHBG
uniprot id: A0A6J1YHP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

32536:HCN3
gene id: 32536:HCN3
uniprot id: A0A6J1YH70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

32536:GAS6
gene id: 32536:GAS6
uniprot id: A0A6J1ZWV0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:HNRNPA2B1
gene id: 32536:HNRNPA2B1
uniprot id: A0A6J0A3X9
names: Subcellular Location Annotation
messages: Cytoplasmic granule

32536:GFRA1
gene id: 32536:GFRA1
uniprot id: A0A6J1ZNL8
uniprot id: A0A6J1ZPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane

32536:NDP
gene id: 32536:NDP
uniprot id: A0A6J1Z0R1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:PPP1R9B
gene id: 32536:PPP1R9B
uniprot id: A0A6J1XBJ6
names: Subcellular Location Annotation
messages: cytoskeleton

32536:TAC3
gene id: 32536:TAC3
uniprot id: A0A6I9ZTU5
uniprot id: A0A6I9ZV07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

32536:ETFA
gene id: 32536:ETFA
uniprot id: A0A6J0A4G8
uniprot id: A0A6J0A5I9
uniprot id: A0A6J2A1E9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

32536:LOC113604224
gene id: 32536:LOC113604224
uniprot id: A0A6J2ANK9
names: Subcellular Location Annotation
messages: Membrane

32536:IHH
gene id: 32536:IHH
uniprot id: A0A6J1YLY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

32536:DECR2
gene id: 32536:DECR2
uniprot id: A0A6I9ZSL7
uniprot id: A0A6I9ZSM0
uniprot id: A0A6I9ZW85
uniprot id: A0A6I9ZW89
uniprot id: A0A6I9ZX81
uniprot id: A0A6J1Y3I5
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
messages: Monomer, dimer and oligomer.

32536:SPESP1
gene id: 32536:SPESP1
uniprot id: A0A6I9ZYI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.
messages: acrosome

32536:LOC106970474
gene id: 32536:LOC106970474
uniprot id: A0A6J1Y2U3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

32536:PEMT
gene id: 32536:PEMT
uniprot id: A0A6J1YEH3
uniprot id: A0A6J1YFT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

32536:CRB2
gene id: 32536:CRB2
uniprot id: A0A6J1XEF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:NACC1
gene id: 32536:NACC1
uniprot id: A0A6J1YQ58
names: Subcellular Location Annotation
messages: Nucleus

32536:POFUT2
gene id: 32536:POFUT2
uniprot id: A0A6J1XXM0
uniprot id: A0A6J1XY91
names: Similarity
messages: Belongs to the glycosyltransferase 68 family.

32536:LOC106986261
gene id: 32536:LOC106986261
uniprot id: A0A6J0A4Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:B3GNT7
gene id: 32536:B3GNT7
uniprot id: A0A6J1YFP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:POLB
gene id: 32536:POLB
uniprot id: A0A6J0A9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

32536:KLC1
gene id: 32536:KLC1
uniprot id: A0A6I9ZQM8
uniprot id: A0A6J1ZY50
uniprot id: A0A6J1ZYK5
uniprot id: A0A6J1ZZB2
uniprot id: A0A6J2A154
uniprot id: A0A6J2A159
uniprot id: A0A6J2A2A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

32536:SERPINB12
gene id: 32536:SERPINB12
uniprot id: A0A6J0A3M2
names: Similarity
messages: Belongs to the serpin family.

32536:LOC106979365
gene id: 32536:LOC106979365
uniprot id: A0A6J1XDJ1
names: Similarity
messages: Belongs to the NipSnap family.

32536:DHCR7
gene id: 32536:DHCR7
uniprot id: A0A6J1Y8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

32536:TMEM87B
gene id: 32536:TMEM87B
uniprot id: A0A6I9ZV70
names: Subcellular Location Annotation
messages: Membrane

32536:RAD23B
gene id: 32536:RAD23B
uniprot id: A0A6J1XDM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

32536:GSDMA
gene id: 32536:GSDMA
uniprot id: A0A6I9ZYJ3
uniprot id: A0A6J1XAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

32536:UBR2
gene id: 32536:UBR2
uniprot id: A0A6I9ZMY9
uniprot id: A0A6I9ZPL1
uniprot id: A0A6J1Z7P8
uniprot id: A0A6J1Z8H4
uniprot id: A0A6J1Z9V4
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

32536:PPIA
gene id: 32536:PPIA
uniprot id: A0A6J1YAR1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:TTYH3
gene id: 32536:TTYH3
uniprot id: A0A6J1XZU0
uniprot id: A0A6J1Y032
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

32536:HYOU1
gene id: 32536:HYOU1
uniprot id: A0A6J1XIY5
uniprot id: A0A6J1XJ14
uniprot id: A0A6J1XJ23
uniprot id: A0A6J1XJ58
uniprot id: A0A6J1XJ62
uniprot id: A0A6J1XJ92
names: Similarity
messages: Belongs to the heat shock protein 70 family.

32536:MAP3K7
gene id: 32536:MAP3K7
uniprot id: A0A6J0A3T1
uniprot id: A0A6J0A4C2
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

32536:NHERF1
gene id: 32536:NHERF1
uniprot id: A0A6J1YVW7
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

32536:GAPVD1
gene id: 32536:GAPVD1
uniprot id: A0A6J1XEK5
uniprot id: A0A6J1XEK6
uniprot id: A0A6J1XEL5
uniprot id: A0A6J1XEL7
uniprot id: A0A6J1XEL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

32536:GRK6
gene id: 32536:GRK6
uniprot id: A0A6J1XFZ5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

32536:NDST2
gene id: 32536:NDST2
uniprot id: A0A6J1ZLX1
uniprot id: A0A6J1ZPE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

32536:LOC106969978
gene id: 32536:LOC106969978
uniprot id: A0A6J2ATW7
names: Similarity
messages: Belongs to the MHC class I family.

32536:KCNMB1
gene id: 32536:KCNMB1
uniprot id: A0A6I9ZQC7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

32536:FSHB
gene id: 32536:FSHB
uniprot id: A0A6I9ZHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

32536:ADK
gene id: 32536:ADK
uniprot id: A0A6I9ZNE0
uniprot id: A0A6I9ZP21
uniprot id: A0A6J1ZL57
uniprot id: A0A6J1ZPK8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

32536:AP5M1
gene id: 32536:AP5M1
uniprot id: A0A6J0A4A1
uniprot id: A0A6J1ZVM4
uniprot id: A0A6J1ZVX9
uniprot id: A0A6J1ZWT8
names: Subcellular Location Annotation
names: Subunit
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: Probably part of the adaptor protein complex 5 (AP-5) a tetramer composed of AP5B1, AP5M1, AP5S1 and AP5Z1.

32536:ACTR3
gene id: 32536:ACTR3
uniprot id: A0A6J1Z2N6
names: Similarity
messages: Belongs to the actin family.

32536:SMARCA5
gene id: 32536:SMARCA5
uniprot id: A0A6J0A220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

32536:MND1
gene id: 32536:MND1
uniprot id: A0A6J0A440
uniprot id: A0A6J2A4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

32536:HACL1
gene id: 32536:HACL1
uniprot id: A0A6J1ZLX5
names: Similarity
messages: Belongs to the TPP enzyme family.

32536:MTERF2
gene id: 32536:MTERF2
uniprot id: A0A6J2AA62
names: Similarity
messages: Belongs to the mTERF family.

32536:CACNA1B
gene id: 32536:CACNA1B
uniprot id: A0A6J1YNV1
uniprot id: A0A6J1YQ82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

32536:USP37
gene id: 32536:USP37
uniprot id: A0A6J1YMY9
uniprot id: A0A6J1YPE7
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:BBS7
gene id: 32536:BBS7
uniprot id: A0A6I9ZWX6
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

32536:LOC106966675
gene id: 32536:LOC106966675
uniprot id: A0A6I9ZDW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

32536:SMOC2
gene id: 32536:SMOC2
uniprot id: A0A6J1Z424
uniprot id: A0A6J1Z4C3
uniprot id: A0A6J1Z5G7
uniprot id: A0A6J1Z601
uniprot id: A0A6J1Z7F5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106987747
gene id: 32536:LOC106987747
uniprot id: A0A6J1YBL7
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:ANK3
gene id: 32536:ANK3
uniprot id: A0A6J1ZK39
uniprot id: A0A6J1ZKG1
uniprot id: A0A6J1ZLA0
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

32536:VPS35
gene id: 32536:VPS35
uniprot id: A0A6J1Y625
uniprot id: A0A6J1Y699
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

32536:GLDC
gene id: 32536:GLDC
uniprot id: A0A6J1YCU7
uniprot id: A0A6J1YE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

32536:CCL5
gene id: 32536:CCL5
uniprot id: A0A6J0A1M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:SORL1
gene id: 32536:SORL1
uniprot id: A0A6J1XJD3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family. SORL1 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Recycling endosome membrane
messages: Secreted
messages: multivesicular body membrane
messages: secretory vesicle membrane
messages: trans-Golgi network membrane

32536:ASB17
gene id: 32536:ASB17
uniprot id: A0A6I9ZZM7
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

32536:BLMH
gene id: 32536:BLMH
uniprot id: A0A6J1XD46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

32536:PIERCE2
gene id: 32536:PIERCE2
uniprot id: A0A6J2A2W4
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

32536:CHST10
gene id: 32536:CHST10
uniprot id: A0A6I9ZGZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:CEP43
gene id: 32536:CEP43
uniprot id: A0A6J1Z470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

32536:SRP9
gene id: 32536:SRP9
uniprot id: A0A6I9ZI94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP9 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm

32536:SLC17A3
gene id: 32536:SLC17A3
uniprot id: A0A6J0A7E4
names: Subcellular Location Annotation
messages: Membrane

32536:SSU72
gene id: 32536:SSU72
uniprot id: A0A6J1ZGB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

32536:UNC45A
gene id: 32536:UNC45A
uniprot id: A0A6J2A2G2
uniprot id: A0A6J2A6C2
names: Subcellular Location Annotation
messages: perinuclear region

32536:EGFL6
gene id: 32536:EGFL6
uniprot id: A0A6J1YZX3
names: Caution
names: Similarity
messages: Belongs to the nephronectin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TIMM9
gene id: 32536:TIMM9
uniprot id: A0A6I9ZU24
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

32536:PIN4
gene id: 32536:PIN4
uniprot id: A0A6J1YVZ5
uniprot id: A0A6J1YW53
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.

32536:OXTR
gene id: 32536:OXTR
uniprot id: A0A6J1Y0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

32536:CHRNB2
gene id: 32536:CHRNB2
uniprot id: A0A6J1YGT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:LTBP3
gene id: 32536:LTBP3
uniprot id: A0A6J1YB43
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:AFF3
gene id: 32536:AFF3
uniprot id: A0A6J2AG94
names: Similarity
messages: Belongs to the AF4 family.

32536:COLGALT1
gene id: 32536:COLGALT1
uniprot id: A0A6J1XNJ4
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

32536:LOC106976553
gene id: 32536:LOC106976553
uniprot id: A0A6I9ZVZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:EPS8L3
gene id: 32536:EPS8L3
uniprot id: A0A6J1ZCY1
names: Similarity
messages: Belongs to the EPS8 family.

32536:ALB
gene id: 32536:ALB
uniprot id: A0A6J0A2J9
names: Subcellular Location Annotation
messages: Secreted

32536:DPYSL5
gene id: 32536:DPYSL5
uniprot id: A0A6J1X9Y7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

32536:LOC106969877
gene id: 32536:LOC106969877
uniprot id: A0A6I9ZM22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ADCY6
gene id: 32536:ADCY6
uniprot id: A0A6J1XH36
uniprot id: A0A6J1XH42
uniprot id: A0A6J1XH54
uniprot id: A0A6J1XHA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

32536:KCNE3
gene id: 32536:KCNE3
uniprot id: A0A6J1XSR7
names: Similarity
messages: Belongs to the potassium channel KCNE family.

32536:SMIM5
gene id: 32536:SMIM5
uniprot id: A0A6J1YSG0
names: Subcellular Location Annotation
messages: Membrane

32536:ALDH16A1
gene id: 32536:ALDH16A1
uniprot id: A0A6J1XN58
uniprot id: A0A6J1XN84
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Interacts with SPG21.

32536:TMEM18
gene id: 32536:TMEM18
uniprot id: A0A6J2AYN4
uniprot id: A0A6J2AZE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

32536:LDHD
gene id: 32536:LDHD
uniprot id: A0A6J0A879
uniprot id: A0A6J2ARS9
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

32536:DIO1
gene id: 32536:DIO1
uniprot id: A0A6I9ZQU2
uniprot id: A0A6I9ZU13
uniprot id: A0A6J1ZCC1
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

32536:KCNE2
gene id: 32536:KCNE2
uniprot id: A0A6I9ZGT6
names: Similarity
messages: Belongs to the potassium channel KCNE family.

32536:FTSJ1
gene id: 32536:FTSJ1
uniprot id: A0A6J0A438
uniprot id: A0A6J0A6P9
uniprot id: A0A6J1YX93
uniprot id: A0A6J1Z0L2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

32536:NFIX
gene id: 32536:NFIX
uniprot id: A0A6J1YMA8
uniprot id: A0A6J1YMB1
uniprot id: A0A6J1YNM6
uniprot id: A0A6J1YNY6
uniprot id: A0A6J1YQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

32536:LOC106980719
gene id: 32536:LOC106980719
uniprot id: A0A6J1XYV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

32536:PCLAF
gene id: 32536:PCLAF
uniprot id: A0A6J0A9V8
uniprot id: A0A6J2A0R5
names: Subcellular Location Annotation
messages: Nucleus
messages: perinuclear region

32536:GOLT1A
gene id: 32536:GOLT1A
uniprot id: A0A6I9ZLB7
uniprot id: A0A6I9ZMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

32536:LOC106973627
gene id: 32536:LOC106973627
uniprot id: A0A6I9ZM92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IGFL family.
messages: Secreted

32536:NFIA
gene id: 32536:NFIA
uniprot id: A0A6J1ZBC3
uniprot id: A0A6J1ZC42
uniprot id: A0A6J1ZCR0
uniprot id: A0A6J1ZCR3
uniprot id: A0A6J1ZDL8
uniprot id: A0A6J1ZES4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

32536:LOC106974984
gene id: 32536:LOC106974984
uniprot id: A0A6J1ZES9
names: Similarity
messages: Belongs to the cytochrome P450 family.

32536:VGLL4
gene id: 32536:VGLL4
uniprot id: A0A6J1Y0L4
uniprot id: A0A6J1Y118
uniprot id: A0A6J1Y1C9
uniprot id: A0A6J1Y1W7
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

32536:NIPAL4
gene id: 32536:NIPAL4
uniprot id: A0A6J2AYU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

32536:LOC106967514
gene id: 32536:LOC106967514
uniprot id: A0A6I9ZIF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MGAT1
gene id: 32536:MGAT1
uniprot id: A0A6J0AAX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

32536:SPICE1
gene id: 32536:SPICE1
uniprot id: A0A6I9ZWP3
uniprot id: A0A6I9ZXN9
uniprot id: A0A6I9ZXY1
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CEP120.
messages: centriole
messages: spindle

32536:LOC106983975
gene id: 32536:LOC106983975
uniprot id: A0A6J1ZA14
names: Similarity
messages: Belongs to the heat shock protein 70 family.

32536:CCNDBP1
gene id: 32536:CCNDBP1
uniprot id: A0A6J1ZZ81
uniprot id: A0A6J1ZZJ8
uniprot id: A0A6J2A286
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

32536:LOC106975758
gene id: 32536:LOC106975758
uniprot id: A0A6I9ZUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

32536:CPT1B
gene id: 32536:CPT1B
uniprot id: A0A6J2A9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:CAMK2G
gene id: 32536:CAMK2G
uniprot id: A0A6J1ZKT7
uniprot id: A0A6J1ZKU5
uniprot id: A0A6J1ZKU9
uniprot id: A0A6J1ZL29
uniprot id: A0A6J1ZL34
uniprot id: A0A6J1ZL39
uniprot id: A0A6J1ZL43
uniprot id: A0A6J1ZLX7
uniprot id: A0A6J1ZLY1
uniprot id: A0A6J1ZN66
uniprot id: A0A6J1ZN72
uniprot id: A0A6J1ZN77
uniprot id: A0A6J1ZPF1
uniprot id: A0A6J1ZPI1
uniprot id: A0A6J1ZPJ6
uniprot id: A0A6J1ZPK3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

32536:D2HGDH
gene id: 32536:D2HGDH
uniprot id: A0A6J1Y9A7
uniprot id: A0A6J1Y9S9
uniprot id: A0A6J1Y9T7
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

32536:TAS2R38
gene id: 32536:TAS2R38
uniprot id: A0A6I9ZN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:PRDM8
gene id: 32536:PRDM8
uniprot id: A0A6J1ZBM7
names: Subcellular Location Annotation
messages: Nucleus

32536:EEF1AKMT1
gene id: 32536:EEF1AKMT1
uniprot id: A0A6J1ZSC0
uniprot id: A0A6J1ZT41
uniprot id: A0A6J1ZW14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

32536:EXOSC1
gene id: 32536:EXOSC1
uniprot id: A0A6I9ZH95
uniprot id: A0A6J1ZM21
names: Subcellular Location Annotation
messages: Cytoplasm

32536:TVP23A
gene id: 32536:TVP23A
uniprot id: A0A6J1Y2V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

32536:ICAM1
gene id: 32536:ICAM1
uniprot id: A0A6J1YNK4
uniprot id: A0A6J1YNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

32536:LOC106986210
gene id: 32536:LOC106986210
uniprot id: A0A6J0A780
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:YRDC
gene id: 32536:YRDC
uniprot id: A0A6J1ZFD3
names: Similarity
messages: Belongs to the SUA5 family.

32536:TOR3A
gene id: 32536:TOR3A
uniprot id: A0A6J2AL15
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

32536:MYB
gene id: 32536:MYB
uniprot id: A0A6J1Z749
uniprot id: A0A6J1Z8H7
names: Subcellular Location Annotation
messages: Nucleus

32536:USP16
gene id: 32536:USP16
uniprot id: A0A6I9ZWH0
uniprot id: A0A6I9ZZQ6
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homotetramer.
messages: Nucleus
messages: Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

32536:ANTXR1
gene id: 32536:ANTXR1
uniprot id: A0A6J2ADU6
uniprot id: A0A6J2AHT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

32536:ATF7IP
gene id: 32536:ATF7IP
uniprot id: A0A6J1XG03
uniprot id: A0A6J1XG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

32536:ANKH
gene id: 32536:ANKH
uniprot id: A0A6I9ZQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKH family.
messages: Membrane
messages: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.

32536:LOC106986500
gene id: 32536:LOC106986500
uniprot id: A0A6J0A7V3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GAMT
gene id: 32536:GAMT
uniprot id: A0A6J1YJQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.
messages: Monomer.

32536:OIP5
gene id: 32536:OIP5
uniprot id: A0A6I9ZK36
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
messages: centromere

32536:UNC50
gene id: 32536:UNC50
uniprot id: A0A6J2AF48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

32536:HAL
gene id: 32536:HAL
uniprot id: A0A6I9ZQ96
names: Similarity
messages: Belongs to the PAL/histidase family.

32536:LOC106970509
gene id: 32536:LOC106970509
uniprot id: A0A6I9ZI09
names: Similarity
messages: Belongs to the peptidase M16 family.

32536:TERT
gene id: 32536:TERT
uniprot id: A0A6J2ALY0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
messages: The RNA-interacting domain 1 (RD1)/N-terminal extension (NTE) is required for interaction with the pseudoknot-template domain of each of TERC dimers. It contains anchor sites that bind primer nucleotides upstream of the RNA-DNA hybrid and is thus an essential determinant of repeat addition processivity.
messages: The RNA-interacting domain 2 (RD2) is essential for both interaction with the CR4-CR5 domain of TERC and for DNA synthesis.
messages: The primer grip sequence in the RT domain is required for telomerase activity and for stable association with short telomeric primers.
messages: nucleolus
messages: nucleoplasm
messages: telomere

32536:LOC106988821
gene id: 32536:LOC106988821
uniprot id: A0A6J0AAS5
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

32536:VPS28
gene id: 32536:VPS28
uniprot id: A0A6J1ZPG0
uniprot id: A0A6J1ZTA9
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

32536:ME1
gene id: 32536:ME1
uniprot id: A0A6J1Z7A8
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

32536:NPY2R
gene id: 32536:NPY2R
uniprot id: A0A6J0A095
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:TADA2A
gene id: 32536:TADA2A
uniprot id: A0A6J1XCB6
uniprot id: A0A6J1XCB8
uniprot id: A0A6J1XCC5
uniprot id: A0A6J1XCD8
names: Subcellular Location Annotation
messages: Nucleus

32536:POLR2C
gene id: 32536:POLR2C
uniprot id: A0A6J2ASW7
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

32536:MED14
gene id: 32536:MED14
uniprot id: A0A6J1YYU6
uniprot id: A0A6J1YZN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

32536:IL2RA
gene id: 32536:IL2RA
uniprot id: A0A6J2AGS3
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

32536:LOC106971491
gene id: 32536:LOC106971491
uniprot id: A0A6I9ZL22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

32536:INTS2
gene id: 32536:INTS2
uniprot id: A0A6I9ZQQ0
uniprot id: A0A6I9ZRL8
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

32536:RORA
gene id: 32536:RORA
uniprot id: A0A6J2A0G7
uniprot id: A0A6J2A470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:IL7
gene id: 32536:IL7
uniprot id: A0A6J0A390
uniprot id: A0A6J0A5Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-7/IL-9 family.
messages: Secreted

32536:MTERF4
gene id: 32536:MTERF4
uniprot id: A0A6J1Y902
names: Similarity
messages: Belongs to the mTERF family.

32536:CDK4
gene id: 32536:CDK4
uniprot id: A0A6I9ZQG2
uniprot id: A0A6I9ZTX0
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:SUGT1
gene id: 32536:SUGT1
uniprot id: A0A6J0A8U2
names: Similarity
messages: Belongs to the SGT1 family.

32536:AVPR1B
gene id: 32536:AVPR1B
uniprot id: A0A6I9ZMW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

32536:AQP10
gene id: 32536:AQP10
uniprot id: A0A6J1YHR5
uniprot id: A0A6J1YHS6
uniprot id: A0A6J1YIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

32536:EMSY
gene id: 32536:EMSY
uniprot id: A0A6I9ZRB7
uniprot id: A0A6I9ZSN6
uniprot id: A0A6I9ZUT2
uniprot id: A0A6I9ZVV4
uniprot id: A0A6J1XS66
uniprot id: A0A6J1XS71
uniprot id: A0A6J1XS91
uniprot id: A0A6J1XS96
uniprot id: A0A6J1XSA0
uniprot id: A0A6J1XSF7
uniprot id: A0A6J1XSK4
uniprot id: A0A6J1XSN1
names: Subcellular Location Annotation
messages: Nucleus

32536:SAMD4A
gene id: 32536:SAMD4A
uniprot id: A0A6J1ZVH6
uniprot id: A0A6J1ZVT3
uniprot id: A0A6J1ZY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

32536:TTYH1
gene id: 32536:TTYH1
uniprot id: A0A6J1XKT3
uniprot id: A0A6J1XKX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

32536:LOC106988434
gene id: 32536:LOC106988434
uniprot id: A0A6J0ABE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106971473
gene id: 32536:LOC106971473
uniprot id: A0A6I9ZPT5
names: Similarity
messages: Belongs to the peptidase C1 family.

32536:LOC106970770
gene id: 32536:LOC106970770
uniprot id: A0A6I9ZIK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106977920
gene id: 32536:LOC106977920
uniprot id: A0A6I9ZWY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:VIPR2
gene id: 32536:VIPR2
uniprot id: A0A6J1YP73
uniprot id: A0A6J1YP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

32536:GALNT11
gene id: 32536:GALNT11
uniprot id: A0A6J1YPG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:CCT2
gene id: 32536:CCT2
uniprot id: A0A6I9ZDK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

32536:ST8SIA2
gene id: 32536:ST8SIA2
uniprot id: A0A6J2A229
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:STX4
gene id: 32536:STX4
uniprot id: A0A6I9ZZS9
uniprot id: A0A6J1YSE1
names: Similarity
messages: Belongs to the syntaxin family.

32536:SNTB2
gene id: 32536:SNTB2
uniprot id: A0A6J2AU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

32536:NTNG1
gene id: 32536:NTNG1
uniprot id: A0A6J1Z9P3
uniprot id: A0A6J1ZAJ7
uniprot id: A0A6J1ZAK2
uniprot id: A0A6J1ZC01
uniprot id: A0A6J1ZD38
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:MBTPS2
gene id: 32536:MBTPS2
uniprot id: A0A6J1YYW3
uniprot id: A0A6J1YYW8
uniprot id: A0A6J1Z042
names: Similarity
messages: Belongs to the peptidase M50A family.

32536:RGS4
gene id: 32536:RGS4
uniprot id: A0A6I9ZCD8
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

32536:DIPK2B
gene id: 32536:DIPK2B
uniprot id: A0A6J1YYJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

32536:CLDN16
gene id: 32536:CLDN16
uniprot id: A0A6I9ZEP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

32536:ECH1
gene id: 32536:ECH1
uniprot id: A0A6J1Y5Z6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

32536:GNB2
gene id: 32536:GNB2
uniprot id: A0A6J1XZQ0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

32536:RPN2
gene id: 32536:RPN2
uniprot id: A0A6J2ABE1
uniprot id: A0A6J2ABV9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

32536:CNTF
gene id: 32536:CNTF
uniprot id: A0A6J0A8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

32536:DHODH
gene id: 32536:DHODH
uniprot id: A0A6J0AAW5
uniprot id: A0A6J2ARI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway.
messages: Mitochondrion inner membrane

32536:RUNDC3A
gene id: 32536:RUNDC3A
uniprot id: A0A6J1YIC7
uniprot id: A0A6J1YID1
uniprot id: A0A6J1YJ86
uniprot id: A0A6J1YKN2
names: Similarity
messages: Belongs to the RUNDC3 family.

32536:LOC106975181
gene id: 32536:LOC106975181
uniprot id: A0A6I9ZUR2
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

32536:GASK1B
gene id: 32536:GASK1B
uniprot id: A0A6J2A235
names: Similarity
messages: Belongs to the GASK family.

32536:ZNF446
gene id: 32536:ZNF446
uniprot id: A0A6J0ABA9
uniprot id: A0A6J1Z196
uniprot id: A0A6J1Z283
uniprot id: A0A6J1Z4D9
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106968330
gene id: 32536:LOC106968330
uniprot id: A0A6J2ASM2
uniprot id: A0A6J2AUY8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

32536:CPSF7
gene id: 32536:CPSF7
uniprot id: A0A6J1Y8U1
uniprot id: A0A6J1Y9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

32536:ATP6AP2
gene id: 32536:ATP6AP2
uniprot id: A0A6J1YY98
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

32536:ZNG1A
gene id: 32536:ZNG1A
uniprot id: A0A6I9ZET5
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

32536:GUCA2A
gene id: 32536:GUCA2A
uniprot id: A0A6I9ZHJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

32536:MYOD1
gene id: 32536:MYOD1
uniprot id: A0A6J2AKA6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

32536:WARS1
gene id: 32536:WARS1
uniprot id: A0A6J0ABB6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:SLC24A3
gene id: 32536:SLC24A3
uniprot id: A0A6J2AAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

32536:MRPS17
gene id: 32536:MRPS17
uniprot id: A0A6I9ZRT1
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

32536:RPS5
gene id: 32536:RPS5
uniprot id: A0A6J1XLR3
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

32536:HCRTR2
gene id: 32536:HCRTR2
uniprot id: A0A6I9ZS39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:CAPN1
gene id: 32536:CAPN1
uniprot id: A0A6J1Y9L5
names: Similarity
messages: Belongs to the peptidase C2 family.

32536:BNIP3L
gene id: 32536:BNIP3L
uniprot id: A0A6J2AT15
uniprot id: A0A6J2AV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

32536:TRPM4
gene id: 32536:TRPM4
uniprot id: A0A6J1XN21
uniprot id: A0A6J1XN28
names: Subcellular Location Annotation
messages: Membrane

32536:GNAL
gene id: 32536:GNAL
uniprot id: A0A6J2A365
uniprot id: A0A6J2A7C1
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

32536:HOXA7
gene id: 32536:HOXA7
uniprot id: A0A6J2ALW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:HFE
gene id: 32536:HFE
uniprot id: A0A6J1XTM1
uniprot id: A0A6J1XTM2
uniprot id: A0A6J1XU26
names: Similarity
messages: Belongs to the MHC class I family.

32536:SLC6A7
gene id: 32536:SLC6A7
uniprot id: A0A6J2AUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

32536:LOC106975763
gene id: 32536:LOC106975763
uniprot id: A0A6I9ZVG7
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

32536:EMP1
gene id: 32536:EMP1
uniprot id: A0A6J1XG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

32536:PPCS
gene id: 32536:PPCS
uniprot id: A0A6J1ZCU8
uniprot id: A0A6J1ZDB6
uniprot id: A0A6J1ZEZ8
names: Similarity
messages: Belongs to the PPC synthetase family.

32536:PDE9A
gene id: 32536:PDE9A
uniprot id: A0A6J1XXU3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:LOC106974874
gene id: 32536:LOC106974874
uniprot id: A0A6I9ZNX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RNF170
gene id: 32536:RNF170
uniprot id: A0A6J2AFP8
uniprot id: A0A6J2AG62
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:SMARCA1
gene id: 32536:SMARCA1
uniprot id: A0A6J1YYE8
uniprot id: A0A6J1YYG1
uniprot id: A0A6J1YZM1
uniprot id: A0A6J1Z1Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

32536:CDH15
gene id: 32536:CDH15
uniprot id: A0A6J2AQC4
uniprot id: A0A6J2AQU2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:LIPH
gene id: 32536:LIPH
uniprot id: A0A6J1ZK85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

32536:PEX1
gene id: 32536:PEX1
uniprot id: A0A6J2ACL7
uniprot id: A0A6J2ACY5
uniprot id: A0A6J2AGZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: cytosol

32536:DUSP1
gene id: 32536:DUSP1
uniprot id: A0A6I9ZPP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

32536:FAM98C
gene id: 32536:FAM98C
uniprot id: A0A6J1Y711
uniprot id: A0A6J1Y745
uniprot id: A0A6J1Y7U6
names: Similarity
messages: Belongs to the FAM98 family.

32536:NSA2
gene id: 32536:NSA2
uniprot id: A0A6J1XU14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

32536:CALR3
gene id: 32536:CALR3
uniprot id: A0A6J1XND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

32536:SHOX2
gene id: 32536:SHOX2
uniprot id: A0A6J1ZIJ4
uniprot id: A0A6J1ZIX7
names: Subcellular Location Annotation
messages: Nucleus

32536:MLLT11
gene id: 32536:MLLT11
uniprot id: A0A6J0A0U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

32536:TAF4B
gene id: 32536:TAF4B
uniprot id: A0A6J2A3X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

32536:ARHGDIG
gene id: 32536:ARHGDIG
uniprot id: A0A6J1Y4B5
names: Similarity
messages: Belongs to the Rho GDI family.

32536:AGTR1
gene id: 32536:AGTR1
uniprot id: A0A6I9ZR20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

32536:RHCG
gene id: 32536:RHCG
uniprot id: A0A6J2A299
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

32536:WAS
gene id: 32536:WAS
uniprot id: A0A6J1YYQ3
names: Subcellular Location Annotation
messages: Nucleus

32536:DYNLL2
gene id: 32536:DYNLL2
uniprot id: A0A6J1XBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

32536:MAP2K2
gene id: 32536:MAP2K2
uniprot id: A0A6J1YKW4
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:LOC106987163
gene id: 32536:LOC106987163
uniprot id: A0A6J0A8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CLDN15
gene id: 32536:CLDN15
uniprot id: A0A6J1XZI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

32536:IDH2
gene id: 32536:IDH2
uniprot id: A0A6J2A5E3
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Homodimer.

32536:OGN
gene id: 32536:OGN
uniprot id: A0A6J0A4A9
names: Similarity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.

32536:ADCY7
gene id: 32536:ADCY7
uniprot id: A0A6J1Y5S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

32536:SLC27A3
gene id: 32536:SLC27A3
uniprot id: A0A6J1YHD8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:CDKL1
gene id: 32536:CDKL1
uniprot id: A0A6J0A352
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:LOC106977819
gene id: 32536:LOC106977819
uniprot id: A0A6I9ZWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SSTR5
gene id: 32536:SSTR5
uniprot id: A0A6J1Y456
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:SMAD1
gene id: 32536:SMAD1
uniprot id: A0A6J2A2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

32536:RHBDD3
gene id: 32536:RHBDD3
uniprot id: A0A6J1YN63
names: Subcellular Location Annotation
messages: Membrane

32536:TMEM120A
gene id: 32536:TMEM120A
uniprot id: A0A6J1XZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

32536:DNPEP
gene id: 32536:DNPEP
uniprot id: A0A6J1YKY8
uniprot id: A0A6J1YM41
uniprot id: A0A6J1YMI5
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

32536:CIAPIN1
gene id: 32536:CIAPIN1
uniprot id: A0A6I9ZTN7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

32536:POLL
gene id: 32536:POLL
uniprot id: A0A6J1ZMS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

32536:DNAAF3
gene id: 32536:DNAAF3
uniprot id: A0A6J1XKS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

32536:UCN3
gene id: 32536:UCN3
uniprot id: A0A6J0AA02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

32536:LIN54
gene id: 32536:LIN54
uniprot id: A0A6J1ZDF2
uniprot id: A0A6J1ZEG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

32536:TK1
gene id: 32536:TK1
uniprot id: A0A6J1YUI7
uniprot id: A0A6J1YV04
names: Similarity
messages: Belongs to the thymidine kinase family.

32536:SLC34A3
gene id: 32536:SLC34A3
uniprot id: A0A6J1YNW6
uniprot id: A0A6J1YNX6
uniprot id: A0A6J1YQA5
uniprot id: A0A6J1YQP0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Membrane

32536:ATP5F1E
gene id: 32536:ATP5F1E
uniprot id: A0A6J1YBK5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

32536:LOC106975074
gene id: 32536:LOC106975074
uniprot id: A0A6I9ZSQ4
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

32536:LOC106975310
gene id: 32536:LOC106975310
uniprot id: A0A6I9ZPI5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

32536:MRPL16
gene id: 32536:MRPL16
uniprot id: A0A6J1Y901
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

32536:HIGD2A
gene id: 32536:HIGD2A
uniprot id: A0A6I9ZUH9
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

32536:KCNAB1
gene id: 32536:KCNAB1
uniprot id: A0A6I9ZL56
uniprot id: A0A6I9ZLK6
uniprot id: A0A6J1ZM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

32536:FERMT2
gene id: 32536:FERMT2
uniprot id: A0A6J1ZVE6
uniprot id: A0A6J1ZVF1
uniprot id: A0A6J1ZVQ9
uniprot id: A0A6J1ZWK9
uniprot id: A0A6J1ZY47
uniprot id: A0A6J1ZZI5
names: Similarity
messages: Belongs to the kindlin family.

32536:LOC106975180
gene id: 32536:LOC106975180
uniprot id: A0A6I9ZU59
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

32536:GPBP1L1
gene id: 32536:GPBP1L1
uniprot id: A0A6J1ZC69
uniprot id: A0A6J1ZCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

32536:TSPAN17
gene id: 32536:TSPAN17
uniprot id: A0A6J1XF02
uniprot id: A0A6J1XF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:LOC106971209
gene id: 32536:LOC106971209
uniprot id: A0A6I9ZJ06
uniprot id: A0A6I9ZM17
uniprot id: A0A6I9ZNL2
names: Subcellular Location Annotation
messages: Membrane

32536:ATP13A3
gene id: 32536:ATP13A3
uniprot id: A0A6J1ZL45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

32536:LOC106988032
gene id: 32536:LOC106988032
uniprot id: A0A6J1XTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:LOC106981133
gene id: 32536:LOC106981133
uniprot id: A0A6J0A2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ACTR3B
gene id: 32536:ACTR3B
uniprot id: A0A6J1YPJ9
uniprot id: A0A6J1YPK7
uniprot id: A0A6J1YRD8
uniprot id: A0A6J1YSN1
names: Similarity
messages: Belongs to the actin family.

32536:HSCB
gene id: 32536:HSCB
uniprot id: A0A6J0A7K1
uniprot id: A0A6J1YMX2
uniprot id: A0A6J1YMZ0
uniprot id: A0A6J1YPA7
names: Similarity
messages: Belongs to the HscB family.

32536:TMEM181
gene id: 32536:TMEM181
uniprot id: A0A6J1Z6B4
names: Subcellular Location Annotation
messages: Membrane

32536:FAM13A
gene id: 32536:FAM13A
uniprot id: A0A6I9ZVK5
uniprot id: A0A6I9ZW30
uniprot id: A0A6J1ZGE9
uniprot id: A0A6J1ZGH6
names: Similarity
messages: Belongs to the FAM13 family.

32536:NXT2
gene id: 32536:NXT2
uniprot id: A0A6J1YZU1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

32536:SDC2
gene id: 32536:SDC2
uniprot id: A0A6J1ZTQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

32536:NAA40
gene id: 32536:NAA40
uniprot id: A0A6J1Y845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

32536:MC3R
gene id: 32536:MC3R
uniprot id: A0A6I9ZMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

32536:LIN28B
gene id: 32536:LIN28B
uniprot id: A0A6J1Z7H5
names: Similarity
messages: Belongs to the lin-28 family.

32536:HMGCL
gene id: 32536:HMGCL
uniprot id: A0A6I9ZXT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

32536:APEX1
gene id: 32536:APEX1
uniprot id: A0A6I9ZMC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

32536:ACADL
gene id: 32536:ACADL
uniprot id: A0A6J1YSS4
uniprot id: A0A6J1YU33
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

32536:LOC106986177
gene id: 32536:LOC106986177
uniprot id: A0A6J0A7G8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TSHZ1
gene id: 32536:TSHZ1
uniprot id: A0A6J2A5B7
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

32536:PSMB11
gene id: 32536:PSMB11
uniprot id: A0A6J2A2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:JAK1
gene id: 32536:JAK1
uniprot id: A0A6J1ZCI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

32536:GHITM
gene id: 32536:GHITM
uniprot id: A0A6J1ZMC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

32536:DMGDH
gene id: 32536:DMGDH
uniprot id: A0A6J1XRT1
uniprot id: A0A6J1XRZ1
names: Similarity
messages: Belongs to the GcvT family.

32536:CLSTN2
gene id: 32536:CLSTN2
uniprot id: A0A6J1ZKD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsyntenin family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Postsynaptic cell membrane

32536:KCNN2
gene id: 32536:KCNN2
uniprot id: A0A6J2AS34
names: Subcellular Location Annotation
messages: Membrane

32536:KARS1
gene id: 32536:KARS1
uniprot id: A0A6J0A1J4
uniprot id: A0A6J0A4A8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

32536:AMBP
gene id: 32536:AMBP
uniprot id: A0A6I9ZUC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

32536:DOCK9
gene id: 32536:DOCK9
uniprot id: A0A6I9ZU15
uniprot id: A0A6I9ZVE8
uniprot id: A0A6I9ZXN8
uniprot id: A0A6I9ZYR5
uniprot id: A0A6J1ZU56
uniprot id: A0A6J1ZUV2
uniprot id: A0A6J1ZUW2
uniprot id: A0A6J1ZWF1
uniprot id: A0A6J1ZWF6
uniprot id: A0A6J1ZXU7
uniprot id: A0A6J1ZXW0
names: Similarity
messages: Belongs to the DOCK family.

32536:FUT11
gene id: 32536:FUT11
uniprot id: A0A6J1ZPE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Predominantly fucosylates the innermost N-acetyl glucosamine (GlcNAc) residue in biantennary N-glycan acceptors.

32536:THG1L
gene id: 32536:THG1L
uniprot id: A0A6J2AUI4
names: Cofactor
names: Similarity
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

32536:TOMM40L
gene id: 32536:TOMM40L
uniprot id: A0A6J1YI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:NOL11
gene id: 32536:NOL11
uniprot id: A0A6I9ZR60
uniprot id: A0A6J1YF48
uniprot id: A0A6J1YF51
names: Subcellular Location Annotation
messages: nucleolus

32536:EIF4ENIF1
gene id: 32536:EIF4ENIF1
uniprot id: A0A6J0A1H0
names: Subcellular Location Annotation
messages: Cytoplasm

32536:ADRM1
gene id: 32536:ADRM1
uniprot id: A0A6J1YDH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

32536:DNASE1
gene id: 32536:DNASE1
uniprot id: A0A6I9ZZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

32536:PREP
gene id: 32536:PREP
uniprot id: A0A6J1Z653
names: Similarity
messages: Belongs to the peptidase S9A family.

32536:SGCE
gene id: 32536:SGCE
uniprot id: A0A6I9ZIQ0
uniprot id: A0A6I9ZM76
uniprot id: A0A6J2ACN6
uniprot id: A0A6J2ACP2
uniprot id: A0A6J2AD16
uniprot id: A0A6J2AD21
uniprot id: A0A6J2AE15
uniprot id: A0A6J2AGL6
uniprot id: A0A6J2AGM1
uniprot id: A0A6J2AH19
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

32536:STN1
gene id: 32536:STN1
uniprot id: A0A6I9ZFU4
uniprot id: A0A6I9ZHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the STN1 family.
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

32536:IL23A
gene id: 32536:IL23A
uniprot id: A0A6J0A5N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

32536:CENPV
gene id: 32536:CENPV
uniprot id: A0A6J1YDU7
uniprot id: A0A6J1YDW4
uniprot id: A0A6J1YEP0
uniprot id: A0A6J1YF72
names: Similarity
messages: Belongs to the Gfa family.

32536:DDX6
gene id: 32536:DDX6
uniprot id: A0A6J1XJ46
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:HOXC8
gene id: 32536:HOXC8
uniprot id: A0A6J1XHY9
names: Subcellular Location Annotation
messages: Nucleus

32536:AP3M2
gene id: 32536:AP3M2
uniprot id: A0A6J0A9G4
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

32536:PRODH2
gene id: 32536:PRODH2
uniprot id: A0A6I9ZQB2
uniprot id: A0A6J1Y7B0
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

32536:LOC106967518
gene id: 32536:LOC106967518
uniprot id: A0A6I9ZIF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PKP1
gene id: 32536:PKP1
uniprot id: A0A6J2API1
names: Similarity
messages: Belongs to the beta-catenin family.

32536:LOC106976624
gene id: 32536:LOC106976624
uniprot id: A0A6I9ZT09
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CPLX1
gene id: 32536:CPLX1
uniprot id: A0A6J1ZNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

32536:CHST1
gene id: 32536:CHST1
uniprot id: A0A6J2AGR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

32536:ST3GAL3
gene id: 32536:ST3GAL3
uniprot id: A0A6J1ZCI7
uniprot id: A0A6J1ZD33
uniprot id: A0A6J1ZDS3
uniprot id: A0A6J1ZER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:LOC106986163
gene id: 32536:LOC106986163
uniprot id: A0A6J0A7F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:COPB2
gene id: 32536:COPB2
uniprot id: A0A6J0A3C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

32536:SUPT5H
gene id: 32536:SUPT5H
uniprot id: A0A6J1Y6X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

32536:RTBDN
gene id: 32536:RTBDN
uniprot id: A0A6J1YMJ2
names: Similarity
messages: Belongs to the folate receptor family.

32536:WNT5B
gene id: 32536:WNT5B
uniprot id: A0A6J2AIY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

32536:LOC106986453
gene id: 32536:LOC106986453
uniprot id: A0A6J0A8M1
names: Similarity
messages: Belongs to the intermediate filament family.

32536:ENTREP2
gene id: 32536:ENTREP2
uniprot id: A0A6J2A4T6
names: Similarity
messages: Belongs to the ENTREP family.

32536:PDSS1
gene id: 32536:PDSS1
uniprot id: A0A6J2AI59
uniprot id: A0A6J2ALS0
uniprot id: A0A6J2AM53
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

32536:MC5R
gene id: 32536:MC5R
uniprot id: A0A6J2A5E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

32536:GPAM
gene id: 32536:GPAM
uniprot id: A0A6J0A317
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

32536:BCOR
gene id: 32536:BCOR
uniprot id: A0A6J1YXM9
uniprot id: A0A6J1YYX9
uniprot id: A0A6J1YZS4
names: Similarity
messages: Belongs to the BCOR family.

32536:NDUFB3
gene id: 32536:NDUFB3
uniprot id: A0A6J0A9T1
uniprot id: A0A6J0AAT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

32536:DPP7
gene id: 32536:DPP7
uniprot id: A0A6J1YWC0
names: Similarity
messages: Belongs to the peptidase S28 family.

32536:CCR4
gene id: 32536:CCR4
uniprot id: A0A6J1XVI2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:UIMC1
gene id: 32536:UIMC1
uniprot id: A0A6J1XF81
uniprot id: A0A6J1XF88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

32536:AKT3
gene id: 32536:AKT3
uniprot id: A0A6I9ZRG9
uniprot id: A0A6J1YBT8
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

32536:MED9
gene id: 32536:MED9
uniprot id: A0A6J1YFB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:MSH2
gene id: 32536:MSH2
uniprot id: A0A6I9ZW18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

32536:PMP22
gene id: 32536:PMP22
uniprot id: A0A6J1YFG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

32536:LOC113604329
gene id: 32536:LOC113604329
uniprot id: A0A6J2AQ13
uniprot id: A0A6J2ARC9
names: Similarity
messages: Belongs to the MORF4 family-associated protein family.

32536:MNAT1
gene id: 32536:MNAT1
uniprot id: A0A6J1ZVT1
uniprot id: A0A6J1ZW35
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

32536:PYGB
gene id: 32536:PYGB
uniprot id: A0A6J2A5X7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

32536:CCNA2
gene id: 32536:CCNA2
uniprot id: A0A6I9ZVX4
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

32536:CELSR2
gene id: 32536:CELSR2
uniprot id: A0A6I9ZYA8
uniprot id: A0A6J1Z9J1
uniprot id: A0A6J1ZAV1
uniprot id: A0A6J1ZBV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

32536:SBDS
gene id: 32536:SBDS
uniprot id: A0A6I9ZMW1
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

32536:DMD
gene id: 32536:DMD
uniprot id: A0A6J1YYU5
uniprot id: A0A6J1YYU9
uniprot id: A0A6J1YYV0
uniprot id: A0A6J1Z015
uniprot id: A0A6J1Z020
uniprot id: A0A6J1Z0U9
names: Subcellular Location Annotation
messages: cytoskeleton

32536:CPA4
gene id: 32536:CPA4
uniprot id: A0A6I9ZSC4
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:PELI2
gene id: 32536:PELI2
uniprot id: A0A6J1ZVK2
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

32536:SLC25A11
gene id: 32536:SLC25A11
uniprot id: A0A6J1YEM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:SEPTIN4
gene id: 32536:SEPTIN4
uniprot id: A0A6J1XC15
uniprot id: A0A6J1XC31
uniprot id: A0A6J1XC32
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

32536:RGR
gene id: 32536:RGR
uniprot id: A0A6J1ZLI9
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106980734
gene id: 32536:LOC106980734
uniprot id: A0A6J0A229
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TYRO3
gene id: 32536:TYRO3
uniprot id: A0A6J2A1X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

32536:BMPR1A
gene id: 32536:BMPR1A
uniprot id: A0A6J1ZLL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

32536:LHX4
gene id: 32536:LHX4
uniprot id: A0A6J2APB5
names: Subcellular Location Annotation
messages: Nucleus

32536:ECI1
gene id: 32536:ECI1
uniprot id: A0A6J1Y378
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

32536:ICAM2
gene id: 32536:ICAM2
uniprot id: A0A6I9ZZB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

32536:MAST4
gene id: 32536:MAST4
uniprot id: A0A6J1XVD6
uniprot id: A0A6J1XVI0
uniprot id: A0A6J1XVX6
uniprot id: A0A6J1XVY8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

32536:P2RY4
gene id: 32536:P2RY4
uniprot id: A0A6J1YXL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:FZD6
gene id: 32536:FZD6
uniprot id: A0A6J1ZR57
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:LOC106986864
gene id: 32536:LOC106986864
uniprot id: A0A6J0A5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MRPL33
gene id: 32536:MRPL33
uniprot id: A0A6I9ZFX4
uniprot id: A0A6I9ZJ70
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

32536:LOC106966703
gene id: 32536:LOC106966703
uniprot id: A0A6J1XVP6
uniprot id: A0A6J1XVW2
uniprot id: A0A6J1XW21
names: Similarity
messages: Belongs to the peptidase C14A family.

32536:FGF21
gene id: 32536:FGF21
uniprot id: A0A6J0A813
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:BNIP1
gene id: 32536:BNIP1
uniprot id: A0A6J1XD83
uniprot id: A0A6J1XD94
names: Subcellular Location Annotation
messages: Membrane

32536:HDAC3
gene id: 32536:HDAC3
uniprot id: A0A6I9ZDH7
uniprot id: A0A6I9ZGF9
uniprot id: A0A6J1Y345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.
messages: Nucleus

32536:PMPCB
gene id: 32536:PMPCB
uniprot id: A0A6I9ZMQ8
names: Similarity
messages: Belongs to the peptidase M16 family.

32536:ANAPC1
gene id: 32536:ANAPC1
uniprot id: A0A6J1XAM6
names: Similarity
messages: Belongs to the APC1 family.

32536:SLC17A6
gene id: 32536:SLC17A6
uniprot id: A0A6J2AK61
names: Subcellular Location Annotation
messages: Membrane

32536:NLRP8
gene id: 32536:NLRP8
uniprot id: A0A6J0A7X4
names: Similarity
messages: Belongs to the NLRP family.

32536:FMNL3
gene id: 32536:FMNL3
uniprot id: A0A6J1XH89
uniprot id: A0A6J1XH92
uniprot id: A0A6J1XHA5
uniprot id: A0A6J1XHG0
names: Similarity
messages: Belongs to the formin homology family.

32536:CASTOR2
gene id: 32536:CASTOR2
uniprot id: A0A6J1XYM4
names: Similarity
messages: Belongs to the GATS family.

32536:XKR4
gene id: 32536:XKR4
uniprot id: A0A6J1Y1I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

32536:HSPB6
gene id: 32536:HSPB6
uniprot id: A0A6J1Y7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: Nucleus

32536:IGFBP4
gene id: 32536:IGFBP4
uniprot id: A0A6J1XAW1
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:SERPINE2
gene id: 32536:SERPINE2
uniprot id: A0A6J1YLM5
names: Similarity
messages: Belongs to the serpin family.

32536:HIP1
gene id: 32536:HIP1
uniprot id: A0A6J1XZW3
names: Similarity
messages: Belongs to the SLA2 family.

32536:STMN1
gene id: 32536:STMN1
uniprot id: A0A6J1ZFK0
names: Similarity
messages: Belongs to the stathmin family.

32536:CHRDL2
gene id: 32536:CHRDL2
uniprot id: A0A6J1XSS2
uniprot id: A0A6J1XT65
names: Subcellular Location Annotation
messages: Secreted

32536:SCAP
gene id: 32536:SCAP
uniprot id: A0A6J1XPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SCAP family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

32536:CCNL1
gene id: 32536:CCNL1
uniprot id: A0A6J1ZJU4
names: Similarity
messages: Belongs to the cyclin family.

32536:LOC106974746
gene id: 32536:LOC106974746
uniprot id: A0A6I9ZTI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TNFSF13
gene id: 32536:TNFSF13
uniprot id: A0A6J1YEH7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

32536:LOC106979547
gene id: 32536:LOC106979547
uniprot id: A0A6J0A0H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ADGRL2
gene id: 32536:ADGRL2
uniprot id: A0A6J1ZAK8
uniprot id: A0A6J1ZAL9
uniprot id: A0A6J1ZBG5
uniprot id: A0A6J1ZBZ3
uniprot id: A0A6J1ZC04
uniprot id: A0A6J1ZCU7
uniprot id: A0A6J1ZE20
names: Subcellular Location Annotation
messages: Membrane

32536:INO80C
gene id: 32536:INO80C
uniprot id: A0A6J2A576
uniprot id: A0A6J2A7S4
names: Subcellular Location Annotation
messages: Nucleus

32536:NIBAN3
gene id: 32536:NIBAN3
uniprot id: A0A6J1XNK4
uniprot id: A0A6J1XNT6
names: Similarity
messages: Belongs to the Niban family.

32536:ASIC1
gene id: 32536:ASIC1
uniprot id: A0A6J1XHB8
uniprot id: A0A6J1XHE1
uniprot id: A0A6J1XHF6
uniprot id: A0A6J1XHJ2
names: Subcellular Location Annotation
messages: Membrane

32536:MRPL2
gene id: 32536:MRPL2
uniprot id: A0A6I9ZR93
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

32536:FLCN
gene id: 32536:FLCN
uniprot id: A0A6J1YGB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

32536:LOC106967273
gene id: 32536:LOC106967273
uniprot id: A0A6I9ZI52
names: Similarity
messages: Belongs to the cytochrome P450 family.

32536:PM20D2
gene id: 32536:PM20D2
uniprot id: A0A6J1Z7Q4
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Catalyzes the peptide bond hydrolysis in dipeptides having basic amino acids lysine, ornithine or arginine at C-terminus.

32536:SMARCB1
gene id: 32536:SMARCB1
uniprot id: A0A6J1YKB5
uniprot id: A0A6J1YKB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

32536:KPNA1
gene id: 32536:KPNA1
uniprot id: A0A6J0A648
uniprot id: A0A6J1ZKI4
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

32536:TIMM17B
gene id: 32536:TIMM17B
uniprot id: A0A6J1Z0U7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

32536:PFN4
gene id: 32536:PFN4
uniprot id: A0A6J1X9U9
names: Similarity
messages: Belongs to the profilin family.

32536:LOC106983502
gene id: 32536:LOC106983502
uniprot id: A0A6J0A1N2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

32536:LOC106969336
gene id: 32536:LOC106969336
uniprot id: A0A6I9ZJA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106973987
gene id: 32536:LOC106973987
uniprot id: A0A6I9ZMS9
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106985217
gene id: 32536:LOC106985217
uniprot id: A0A6J1YQN6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:ANAPC16
gene id: 32536:ANAPC16
uniprot id: A0A6I9ZDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

32536:SNX3
gene id: 32536:SNX3
uniprot id: A0A6J1Z6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: phagosome

32536:ALKBH1
gene id: 32536:ALKBH1
uniprot id: A0A6I9ZRP1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

32536:ZNF711
gene id: 32536:ZNF711
uniprot id: A0A6J1YWM2
uniprot id: A0A6J1YYG0
uniprot id: A0A6J1YZV9
names: Subcellular Location Annotation
messages: Nucleus

32536:CASP9
gene id: 32536:CASP9
uniprot id: A0A6J1ZFA5
uniprot id: A0A6J1ZHL5
names: Similarity
messages: Belongs to the peptidase C14A family.

32536:RCAN2
gene id: 32536:RCAN2
uniprot id: A0A6I9ZTC5
uniprot id: A0A6J1Z860
names: Function
names: Similarity
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.

32536:LOC106979542
gene id: 32536:LOC106979542
uniprot id: A0A6I9ZX66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GLYATL3
gene id: 32536:GLYATL3
uniprot id: A0A6I9ZR29
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

32536:TRPM1
gene id: 32536:TRPM1
uniprot id: A0A6J2A1J0
names: Subcellular Location Annotation
messages: Membrane

32536:RPA2
gene id: 32536:RPA2
uniprot id: A0A6I9ZXF8
names: Similarity
messages: Belongs to the replication factor A protein 2 family.

32536:FAM124B
gene id: 32536:FAM124B
uniprot id: A0A6I9ZNW0
names: Similarity
messages: Belongs to the FAM124 family.

32536:LOC106977895
gene id: 32536:LOC106977895
uniprot id: A0A6J1Y8J5
names: Similarity
messages: Belongs to the MS4A family.

32536:CSF3R
gene id: 32536:CSF3R
uniprot id: A0A6I9ZLR4
uniprot id: A0A6I9ZQ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

32536:CCNK
gene id: 32536:CCNK
uniprot id: A0A6J1ZXT0
names: Similarity
messages: Belongs to the cyclin family.

32536:INKA1
gene id: 32536:INKA1
uniprot id: A0A6J1XPU3
uniprot id: A0A6J1XQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

32536:ACSL5
gene id: 32536:ACSL5
uniprot id: A0A6J0A2Z5
uniprot id: A0A6J0A313
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

32536:MBTD1
gene id: 32536:MBTD1
uniprot id: A0A6J0A877
uniprot id: A0A6J1XBS7
uniprot id: A0A6J1XBU1
uniprot id: A0A6J1XBU3
uniprot id: A0A6J1XBU4
uniprot id: A0A6J1XBV1
uniprot id: A0A6J1XBV2
names: Subcellular Location Annotation
messages: Nucleus

32536:QPRT
gene id: 32536:QPRT
uniprot id: A0A6J1YRP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

32536:SLC9A5
gene id: 32536:SLC9A5
uniprot id: A0A6J2APH8
uniprot id: A0A6J2AT81
uniprot id: A0A6J2ATP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane
messages: Recycling endosome membrane

32536:SMG5
gene id: 32536:SMG5
uniprot id: A0A6J1YHK0
uniprot id: A0A6J1YJ12
uniprot id: A0A6J1YJS8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays a role in nonsense-mediated mRNA decay.

32536:LOC113593855
gene id: 32536:LOC113593855
uniprot id: A0A6J1XTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:CTSC
gene id: 32536:CTSC
uniprot id: A0A6I9ZH66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

32536:PIGC
gene id: 32536:PIGC
uniprot id: A0A6J1YB26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

32536:TTC21B
gene id: 32536:TTC21B
uniprot id: A0A6J0A441
names: Similarity
messages: Belongs to the TTC21 family.

32536:TMOD1
gene id: 32536:TMOD1
uniprot id: A0A6J1XS92
names: Subcellular Location Annotation
messages: cytoskeleton

32536:SGSM2
gene id: 32536:SGSM2
uniprot id: A0A6J1XD88
uniprot id: A0A6J1XDB5
names: Similarity
messages: Belongs to the RUTBC family.

32536:HCFC1
gene id: 32536:HCFC1
uniprot id: A0A6J1YVB5
uniprot id: A0A6J1YX39
uniprot id: A0A6J1YYK8
names: Subcellular Location Annotation
messages: Nucleus

32536:HGF
gene id: 32536:HGF
uniprot id: A0A6I9ZQ14
uniprot id: A0A6J2ADJ6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

32536:ACVR2B
gene id: 32536:ACVR2B
uniprot id: A0A6J1XVK9
uniprot id: A0A6J1XVS8
uniprot id: A0A6J1XVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

32536:GPR37L1
gene id: 32536:GPR37L1
uniprot id: A0A6J2AL05
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:MRPL19
gene id: 32536:MRPL19
uniprot id: A0A6I9ZLD9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

32536:CUX1
gene id: 32536:CUX1
uniprot id: A0A6J1XZ34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASP family.
messages: Golgi apparatus membrane
messages: Membrane

32536:NTMT2
gene id: 32536:NTMT2
uniprot id: A0A6J1YAW6
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

32536:UTP6
gene id: 32536:UTP6
uniprot id: A0A6J0A2P0
uniprot id: A0A6J1XCM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP6 family.
messages: nucleolus

32536:MUSTN1
gene id: 32536:MUSTN1
uniprot id: A0A6J1XRD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

32536:LOC106980965
gene id: 32536:LOC106980965
uniprot id: A0A6I9ZYX6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

32536:NPC1L1
gene id: 32536:NPC1L1
uniprot id: A0A6J1YA34
names: Similarity
messages: Belongs to the patched family.

32536:CSNK1G1
gene id: 32536:CSNK1G1
uniprot id: A0A6J0A668
uniprot id: A0A6J2A0F6
uniprot id: A0A6J2A0G3
uniprot id: A0A6J2A1I7
uniprot id: A0A6J2A3G7
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

32536:LTB4R2
gene id: 32536:LTB4R2
uniprot id: A0A6J1ZUM9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:POLR1A
gene id: 32536:POLR1A
uniprot id: A0A6I9ZYC2
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

32536:LOC106987144
gene id: 32536:LOC106987144
uniprot id: A0A6J0A9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PARP6
gene id: 32536:PARP6
uniprot id: A0A6J2A111
uniprot id: A0A6J2A1A5
uniprot id: A0A6J2A230
uniprot id: A0A6J2A426
names: Similarity
messages: Belongs to the ARTD/PARP family.

32536:IRAK4
gene id: 32536:IRAK4
uniprot id: A0A6I9ZYK7
uniprot id: A0A6J1XH14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

32536:MEIS3
gene id: 32536:MEIS3
uniprot id: A0A6J1XMG7
uniprot id: A0A6J1XMH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

32536:TLE3
gene id: 32536:TLE3
uniprot id: A0A6J2A0X0
uniprot id: A0A6J2A0X5
uniprot id: A0A6J2A169
uniprot id: A0A6J2A1Z1
uniprot id: A0A6J2A1Z6
uniprot id: A0A6J2A3Y3
uniprot id: A0A6J2A4X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

32536:SERINC2
gene id: 32536:SERINC2
uniprot id: A0A6J1ZDW3
uniprot id: A0A6J1ZE90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

32536:MSI1
gene id: 32536:MSI1
uniprot id: A0A6J1Y498
uniprot id: A0A6J1Y4U4
uniprot id: A0A6J1Y4Z2
uniprot id: A0A6J1Y5Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Musashi family.
messages: Cytoplasm

32536:LOC106988031
gene id: 32536:LOC106988031
uniprot id: A0A6J1XTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:OXT
gene id: 32536:OXT
uniprot id: A0A6J2A6N0
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

32536:MFSD3
gene id: 32536:MFSD3
uniprot id: A0A6J1ZRZ5
names: Subcellular Location Annotation
messages: Membrane

32536:DNAAF8
gene id: 32536:DNAAF8
uniprot id: A0A6J1Y343
names: Function
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

32536:TERF2IP
gene id: 32536:TERF2IP
uniprot id: A0A6J2AUM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

32536:PALS2
gene id: 32536:PALS2
uniprot id: A0A6J2AM78
uniprot id: A0A6J2ARC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane

32536:POPDC3
gene id: 32536:POPDC3
uniprot id: A0A6J1Z6W6
names: Similarity
messages: Belongs to the popeye family.

32536:GRK2
gene id: 32536:GRK2
uniprot id: A0A6J1Y7Z7
uniprot id: A0A6J1Y953
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

32536:LPAR3
gene id: 32536:LPAR3
uniprot id: A0A6J1ZBV1
uniprot id: A0A6J1ZDW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:RPS26
gene id: 32536:RPS26
uniprot id: A0A6J0A5N8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

32536:CHMP6
gene id: 32536:CHMP6
uniprot id: A0A6J1YSD1
names: Similarity
messages: Belongs to the SNF7 family.

32536:TRAM1
gene id: 32536:TRAM1
uniprot id: A0A6J1ZRR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

32536:TCL1A
gene id: 32536:TCL1A
uniprot id: A0A6I9ZQW4
names: Similarity
messages: Belongs to the TCL1 family.

32536:HAGHL
gene id: 32536:HAGHL
uniprot id: A0A6J1Y3F9
uniprot id: A0A6J1Y468
uniprot id: A0A6J1Y5F7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

32536:MCL1
gene id: 32536:MCL1
uniprot id: A0A6J0A7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Membrane
messages: nucleoplasm

32536:ENO3
gene id: 32536:ENO3
uniprot id: A0A6J1YGP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

32536:LOC106989350
gene id: 32536:LOC106989350
uniprot id: A0A6J0A8U3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:CALHM2
gene id: 32536:CALHM2
uniprot id: A0A6J1ZQ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

32536:MRGPRX2
gene id: 32536:MRGPRX2
uniprot id: A0A6J1Z1X0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:OLFM1
gene id: 32536:OLFM1
uniprot id: A0A6J0AC42
uniprot id: A0A6J1YQN8
uniprot id: A0A6J1YS38
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

32536:SLC2A12
gene id: 32536:SLC2A12
uniprot id: A0A6J1Z6H6
uniprot id: A0A6J1Z759
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

32536:OLA1
gene id: 32536:OLA1
uniprot id: A0A6J1Z2M1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.
messages: Nucleus
messages: nucleolus

32536:KRT84
gene id: 32536:KRT84
uniprot id: A0A6J1XHR3
names: Similarity
messages: Belongs to the intermediate filament family.

32536:SENP6
gene id: 32536:SENP6
uniprot id: A0A6J1Z6Q0
uniprot id: A0A6J1Z7G3
uniprot id: A0A6J1ZA71
names: Similarity
messages: Belongs to the peptidase C48 family.

32536:DDAH2
gene id: 32536:DDAH2
uniprot id: A0A6J0A5D3
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

32536:EIF4E
gene id: 32536:EIF4E
uniprot id: A0A6J1ZHS0
uniprot id: A0A6J1ZHS6
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

32536:LFNG
gene id: 32536:LFNG
uniprot id: A0A6J1Y0H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:PLD4
gene id: 32536:PLD4
uniprot id: A0A6J1ZZG9
names: Similarity
messages: Belongs to the phospholipase D family.

32536:MEF2A
gene id: 32536:MEF2A
uniprot id: A0A6J2A1Z5
uniprot id: A0A6J2A2V7
uniprot id: A0A6J2A4Z8
uniprot id: A0A6J2A5R9
names: Subcellular Location Annotation
messages: Nucleus

32536:ETV4
gene id: 32536:ETV4
uniprot id: A0A6J1YI11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:LOC106987548
gene id: 32536:LOC106987548
uniprot id: A0A6J2AJA6
names: Similarity
messages: Belongs to the SELO family.

32536:ITIH1
gene id: 32536:ITIH1
uniprot id: A0A6J0A8P2
uniprot id: A0A6J1XQQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

32536:MRPS18A
gene id: 32536:MRPS18A
uniprot id: A0A6I9ZMV5
uniprot id: A0A6I9ZTD4
names: Subcellular Location Annotation
messages: Mitochondrion

32536:SQLE
gene id: 32536:SQLE
uniprot id: A0A6J0A7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

32536:SLC66A1
gene id: 32536:SLC66A1
uniprot id: A0A6J0A482
uniprot id: A0A6J1ZF26
names: Subcellular Location Annotation
messages: Membrane

32536:PMIS2
gene id: 32536:PMIS2
uniprot id: A0A6J1Y6N9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

32536:ATL2
gene id: 32536:ATL2
uniprot id: A0A6J1X6W0
uniprot id: A0A6J1X7L8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

32536:RIOK2
gene id: 32536:RIOK2
uniprot id: A0A6I9ZHN1
uniprot id: A0A6J1XL43
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

32536:FARS2
gene id: 32536:FARS2
uniprot id: A0A6J1XTY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

32536:INIP
gene id: 32536:INIP
uniprot id: A0A6I9ZJV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

32536:ACTA2
gene id: 32536:ACTA2
uniprot id: A0A6J0A2D4
names: Similarity
messages: Belongs to the actin family.

32536:PLPBP
gene id: 32536:PLPBP
uniprot id: A0A6J2ACC9
uniprot id: A0A6J2ACD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

32536:LOC106985516
gene id: 32536:LOC106985516
uniprot id: A0A6J1ZS56
uniprot id: A0A6J1ZTA0
uniprot id: A0A6J1ZUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

32536:LOC106976320
gene id: 32536:LOC106976320
uniprot id: A0A6I9ZUL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CUTC
gene id: 32536:CUTC
uniprot id: A0A6I9ZFP2
uniprot id: A0A6I9ZHF5
names: Similarity
messages: Belongs to the CutC family.

32536:LOC106979745
gene id: 32536:LOC106979745
uniprot id: A0A6I9ZWH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

32536:KCNJ6
gene id: 32536:KCNJ6
uniprot id: A0A6J1XYT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

32536:TMCC2
gene id: 32536:TMCC2
uniprot id: A0A6J2ALG1
uniprot id: A0A6J2AQK1
names: Similarity
messages: Belongs to the TEX28 family.

32536:WDR46
gene id: 32536:WDR46
uniprot id: A0A6I9ZQV0
names: Subcellular Location Annotation
messages: nucleolus

32536:SEC62
gene id: 32536:SEC62
uniprot id: A0A6J1ZLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:PDHB
gene id: 32536:PDHB
uniprot id: A0A6I9ZKL9
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

32536:MRPS18C
gene id: 32536:MRPS18C
uniprot id: A0A6J0A9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

32536:CPPED1
gene id: 32536:CPPED1
uniprot id: A0A6I9ZL75
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

32536:FOXH1
gene id: 32536:FOXH1
uniprot id: A0A6J1ZS04
names: Subcellular Location Annotation
messages: Nucleus

32536:STK17B
gene id: 32536:STK17B
uniprot id: A0A6J1YXX7
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:CD14
gene id: 32536:CD14
uniprot id: A0A6I9ZIJ3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR4. Interacts with LPAR1.
messages: Cell membrane
messages: Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
messages: Golgi apparatus
messages: Membrane raft
messages: Secreted

32536:IAH1
gene id: 32536:IAH1
uniprot id: A0A6J2AUT1
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

32536:TMEM263
gene id: 32536:TMEM263
uniprot id: A0A6J2AE98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

32536:FBP1
gene id: 32536:FBP1
uniprot id: A0A6I9ZP13
names: Similarity
messages: Belongs to the FBPase class 1 family.

32536:LOC106984174
gene id: 32536:LOC106984174
uniprot id: A0A6J0A2G8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

32536:ELMO1
gene id: 32536:ELMO1
uniprot id: A0A6J2AR95
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

32536:RPL30
gene id: 32536:RPL30
uniprot id: A0A6J0A5V1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

32536:RELN
gene id: 32536:RELN
uniprot id: A0A6J2ADH3
uniprot id: A0A6J2AGJ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

32536:MFF
gene id: 32536:MFF
uniprot id: A0A6I9ZKP7
uniprot id: A0A6I9ZM67
uniprot id: A0A6I9ZNV5
uniprot id: A0A6I9ZQ89
uniprot id: A0A6I9ZQ94
uniprot id: A0A6I9ZR32
uniprot id: A0A6I9ZR36
uniprot id: A0A6J1YI49
uniprot id: A0A6J1YI64
uniprot id: A0A6J1YIY1
uniprot id: A0A6J1YKB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.
messages: synaptic vesicle

32536:LOC106976611
gene id: 32536:LOC106976611
uniprot id: A0A6I9ZW35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DCTN5
gene id: 32536:DCTN5
uniprot id: A0A6I9ZML1
uniprot id: A0A6I9ZN62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 5 subfamily.
messages: cytoskeleton

32536:MLF2
gene id: 32536:MLF2
uniprot id: A0A6J2AIX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

32536:TOP2A
gene id: 32536:TOP2A
uniprot id: A0A6J0A0Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: nucleolus
messages: nucleoplasm

32536:SCNN1A
gene id: 32536:SCNN1A
uniprot id: A0A6J2AKJ7
names: Subcellular Location Annotation
messages: Membrane

32536:PTGS1
gene id: 32536:PTGS1
uniprot id: A0A6J1XEC7
names: Caution
names: Similarity
messages: Belongs to the prostaglandin G/H synthase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:VRK1
gene id: 32536:VRK1
uniprot id: A0A6J1ZXS0
uniprot id: A0A6J1ZY60
uniprot id: A0A6J2A0P5
uniprot id: A0A6J2A1W5
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:SELENOK
gene id: 32536:SELENOK
uniprot id: A0A6J0A8G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

32536:ITIH5
gene id: 32536:ITIH5
uniprot id: A0A6J2AKW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

32536:FAM118A
gene id: 32536:FAM118A
uniprot id: A0A6J2A8T1
uniprot id: A0A6J2A8X0
uniprot id: A0A6J2A9U7
uniprot id: A0A6J2A9V1
names: Similarity
messages: Belongs to the FAM118 family.

32536:ALDOB
gene id: 32536:ALDOB
uniprot id: A0A6I9ZQP7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

32536:TNFAIP6
gene id: 32536:TNFAIP6
uniprot id: A0A6J1Z2B3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LAMB3
gene id: 32536:LAMB3
uniprot id: A0A6J2AP66
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TSHZ2
gene id: 32536:TSHZ2
uniprot id: A0A6J1YC11
uniprot id: A0A6J1YDA0
uniprot id: A0A6J1YDZ5
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

32536:PSMA5
gene id: 32536:PSMA5
uniprot id: A0A6I9ZT26
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

32536:POP7
gene id: 32536:POP7
uniprot id: A0A6J0A906
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone-like Alba family.
messages: Component of nuclear RNase P and RNase MRP complexes. RNase P consists of a catalytic RNA moiety and 10 different protein chains; POP1, POP4, POP5, POP7, RPP14, RPP21, RPP25, RPP30, RPP38 and RPP40. Within the RNase P complex, POP1, POP7 and RPP25 form the 'finger' subcomplex, POP5, RPP14, RPP40 and homodimeric RPP30 form the 'palm' subcomplex, and RPP21, POP4 and RPP38 form the 'wrist' subcomplex. All subunits of the RNase P complex interact with the catalytic RNA. Several subunits of RNase P are also part of the RNase MRP complex. RNase MRP consists of a catalytic RNA moiety and about 8 protein subunits; POP1, POP7, RPP25, RPP30, RPP38, RPP40 and possibly also POP4 and POP5. Interacts with SMN1. POP7 forms a heterodimer with RPP25 that binds to the P3 stem loop of the catalytic RNA.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
messages: Cytoplasmic granule
messages: nucleolus

32536:MARVELD2
gene id: 32536:MARVELD2
uniprot id: A0A6J1XV88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

32536:TSPAN1
gene id: 32536:TSPAN1
uniprot id: A0A6I9ZLU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:PALM3
gene id: 32536:PALM3
uniprot id: A0A6J1YMR1
names: Similarity
messages: Belongs to the paralemmin family.

32536:STMN4
gene id: 32536:STMN4
uniprot id: A0A6I9ZLL4
uniprot id: A0A6I9ZN78
uniprot id: A0A6I9ZPW5
uniprot id: A0A6I9ZS67
names: Similarity
messages: Belongs to the stathmin family.

32536:VPS37A
gene id: 32536:VPS37A
uniprot id: A0A6J2AT42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

32536:LOC106965834
gene id: 32536:LOC106965834
uniprot id: A0A6J1ZM65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

32536:GTF2IRD1
gene id: 32536:GTF2IRD1
uniprot id: A0A6J1XYN3
names: Subcellular Location Annotation
messages: Nucleus

32536:HUS1
gene id: 32536:HUS1
uniprot id: A0A6I9ZJF7
uniprot id: A0A6J1YBA4
names: Similarity
messages: Belongs to the HUS1 family.

32536:EPGN
gene id: 32536:EPGN
uniprot id: A0A6J0A2R8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PRLR
gene id: 32536:PRLR
uniprot id: A0A6I9ZZD2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

32536:VASN
gene id: 32536:VASN
uniprot id: A0A6J1Y4C3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:EHD3
gene id: 32536:EHD3
uniprot id: A0A6I9ZJ83
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

32536:CHMP4C
gene id: 32536:CHMP4C
uniprot id: A0A6J0A478
names: Similarity
messages: Belongs to the SNF7 family.

32536:ZRANB2
gene id: 32536:ZRANB2
uniprot id: A0A6J0A0K2
uniprot id: A0A6J0A3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: Nucleus
messages: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.

32536:TM9SF4
gene id: 32536:TM9SF4
uniprot id: A0A6J2A707
uniprot id: A0A6J2AAR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

32536:AK4
gene id: 32536:AK4
uniprot id: A0A6J1ZBY8
uniprot id: A0A6J1ZDF6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

32536:RC3H1
gene id: 32536:RC3H1
uniprot id: A0A6J2AJ67
uniprot id: A0A6J2AKT7
names: Subcellular Location Annotation
messages: P-body

32536:SETD7
gene id: 32536:SETD7
uniprot id: A0A6J2A030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
messages: Chromosome
messages: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes.
messages: Nucleus

32536:MRPL54
gene id: 32536:MRPL54
uniprot id: A0A6J1YJ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

32536:IZUMO3
gene id: 32536:IZUMO3
uniprot id: A0A6J0A125
names: Similarity
messages: Belongs to the Izumo family.

32536:LOC106985218
gene id: 32536:LOC106985218
uniprot id: A0A6J1YMS5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:LOC106966153
gene id: 32536:LOC106966153
uniprot id: A0A6I9ZBU0
uniprot id: A0A6I9ZGE4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:DACT3
gene id: 32536:DACT3
uniprot id: A0A6J1XMC2
names: Similarity
messages: Belongs to the dapper family.

32536:LOC113598097
gene id: 32536:LOC113598097
uniprot id: A0A6J1Z0R9
names: Subcellular Location Annotation
messages: Nucleus

32536:KCNAB3
gene id: 32536:KCNAB3
uniprot id: A0A6J1YEA9
uniprot id: A0A6J1YF49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cytoplasm

32536:AMPD2
gene id: 32536:AMPD2
uniprot id: A0A6J1Z9I3
uniprot id: A0A6J1ZAE0
uniprot id: A0A6J1ZAU1
uniprot id: A0A6J1ZBU3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

32536:PARD6A
gene id: 32536:PARD6A
uniprot id: A0A6I9ZKQ1
uniprot id: A0A6J2ATE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

32536:GFRAL
gene id: 32536:GFRAL
uniprot id: A0A6J1ZAP0
names: Similarity
messages: Belongs to the GDNFR family.

32536:RPS15
gene id: 32536:RPS15
uniprot id: A0A6J1YKS3
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Component of the small ribosomal subunit.

32536:GPSM2
gene id: 32536:GPSM2
uniprot id: A0A6J1Z9L8
uniprot id: A0A6J1ZAY5
uniprot id: A0A6J1ZD24
names: Similarity
messages: Belongs to the GPSM family.

32536:MYC
gene id: 32536:MYC
uniprot id: A0A6J1ZQM7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
messages: nucleolus
messages: nucleoplasm

32536:BRPF3
gene id: 32536:BRPF3
uniprot id: A0A6J1Z831
uniprot id: A0A6J1Z8X4
uniprot id: A0A6J1ZA97
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106981563
gene id: 32536:LOC106981563
uniprot id: A0A6I9ZZ28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ADAM19
gene id: 32536:ADAM19
uniprot id: A0A6J2AZM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TIGD3
gene id: 32536:TIGD3
uniprot id: A0A6J1Y8Q6
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106973302
gene id: 32536:LOC106973302
uniprot id: A0A6I9ZNG3
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

32536:EIF5B
gene id: 32536:EIF5B
uniprot id: A0A6I9ZK35
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.

32536:RSPO3
gene id: 32536:RSPO3
uniprot id: A0A6I9ZRU4
uniprot id: A0A6I9ZTB0
names: Similarity
messages: Belongs to the R-spondin family.

32536:CRYAB
gene id: 32536:CRYAB
uniprot id: A0A6J1XIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA.
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

32536:TNPO2
gene id: 32536:TNPO2
uniprot id: A0A6J1YL79
uniprot id: A0A6J1YL83
uniprot id: A0A6J1YMU1
names: Subcellular Location Annotation
messages: Cytoplasm

32536:LOC106967104
gene id: 32536:LOC106967104
uniprot id: A0A6I9ZHT9
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:ALOX5
gene id: 32536:ALOX5
uniprot id: A0A6J1ZMM9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:METTL8
gene id: 32536:METTL8
uniprot id: A0A6J0A9G6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

32536:TNMD
gene id: 32536:TNMD
uniprot id: A0A6J0A1P3
uniprot id: A0A6J0A4G3
names: Similarity
messages: Belongs to the chondromodulin-1 family.

32536:CARM1
gene id: 32536:CARM1
uniprot id: A0A6J1YMU4
names: Subcellular Location Annotation
messages: Nucleus

32536:CTNNA2
gene id: 32536:CTNNA2
uniprot id: A0A6J2AD81
uniprot id: A0A6J2ADM1
uniprot id: A0A6J2AEL2
uniprot id: A0A6J2AH74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

32536:PSMD9
gene id: 32536:PSMD9
uniprot id: A0A6I9ZDT5
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

32536:PPME1
gene id: 32536:PPME1
uniprot id: A0A6I9ZX53
uniprot id: A0A6J1XSR3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

32536:SGSH
gene id: 32536:SGSH
uniprot id: A0A6J1YWB8
names: Similarity
messages: Belongs to the sulfatase family.

32536:TSSK4
gene id: 32536:TSSK4
uniprot id: A0A6J0A6Y7
uniprot id: A0A6J0A9M9
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:RPS6KB2
gene id: 32536:RPS6KB2
uniprot id: A0A6J1Y8Y6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

32536:PGM2L1
gene id: 32536:PGM2L1
uniprot id: A0A6I9ZTI1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

32536:LOC106986011
gene id: 32536:LOC106986011
uniprot id: A0A6J0A6X7
uniprot id: A0A6J2A6X9
uniprot id: A0A6J2A6Y4
uniprot id: A0A6J2AB52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

32536:EML6
gene id: 32536:EML6
uniprot id: A0A6J2AIL2
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

32536:PACS1
gene id: 32536:PACS1
uniprot id: A0A6J1Y9K9
uniprot id: A0A6J1YA71
names: Similarity
messages: Belongs to the PACS family.

32536:FOXD2
gene id: 32536:FOXD2
uniprot id: A0A6J1ZCP4
names: Subcellular Location Annotation
messages: Nucleus

32536:KCNJ11
gene id: 32536:KCNJ11
uniprot id: A0A6I9ZU80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

32536:ADCY4
gene id: 32536:ADCY4
uniprot id: A0A6J1ZYT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

32536:SLC25A14
gene id: 32536:SLC25A14
uniprot id: A0A6J1YXU6
uniprot id: A0A6J1YXV7
uniprot id: A0A6J1YZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:LOC106989735
gene id: 32536:LOC106989735
uniprot id: A0A6J1XW16
names: Similarity
messages: Belongs to the SPATA31 family.

32536:LOC106979004
gene id: 32536:LOC106979004
uniprot id: A0A6I9ZZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:FLAD1
gene id: 32536:FLAD1
uniprot id: A0A6J0AA98
uniprot id: A0A6J1YGZ8
uniprot id: A0A6J1YID8
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

32536:KDELR1
gene id: 32536:KDELR1
uniprot id: A0A6J1XML8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PFKFB1
gene id: 32536:PFKFB1
uniprot id: A0A6J1YVP3
uniprot id: A0A6J1YVT4
uniprot id: A0A6J1YXK8
uniprot id: A0A6J1YZ31
names: Similarity
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

32536:LOC106988049
gene id: 32536:LOC106988049
uniprot id: A0A0A0Y301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:NUDT19
gene id: 32536:NUDT19
uniprot id: A0A6J1Y642
names: Similarity
messages: Belongs to the Nudix hydrolase family.

32536:RAB21
gene id: 32536:RAB21
uniprot id: A0A6I9ZF17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: trans-Golgi network

32536:CD38
gene id: 32536:CD38
uniprot id: A0A6I9ZQ08
uniprot id: A0A6J1XU67
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

32536:LOC106969045
gene id: 32536:LOC106969045
uniprot id: A0A6J1XPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

32536:NDNF
gene id: 32536:NDNF
uniprot id: A0A6J0A0C9
names: Subcellular Location Annotation
messages: Secreted

32536:KDM3B
gene id: 32536:KDM3B
uniprot id: A0A6J2AQU1
uniprot id: A0A6J2ARA4
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JHDM2 histone demethylase family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code.
messages: Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
messages: Nucleus
messages: The JmjC domain and the C6-type zinc-finger are required for the demethylation activity.

32536:ST8SIA3
gene id: 32536:ST8SIA3
uniprot id: A0A6J0A1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

32536:MRPL11
gene id: 32536:MRPL11
uniprot id: A0A6I9ZIZ7
uniprot id: A0A6I9ZM14
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

32536:CENPK
gene id: 32536:CENPK
uniprot id: A0A6J1XWA6
uniprot id: A0A6J1XWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: centromere

32536:TNFRSF6B
gene id: 32536:TNFRSF6B
uniprot id: A0A6J1YDV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:IL3RA
gene id: 32536:IL3RA
uniprot id: A0A6J1YXF0
names: Subcellular Location Annotation
messages: Membrane

32536:CDC37L1
gene id: 32536:CDC37L1
uniprot id: A0A6J1XWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

32536:SEC24C
gene id: 32536:SEC24C
uniprot id: A0A6J1ZKS7
uniprot id: A0A6J1ZL20
uniprot id: A0A6J1ZN56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

32536:LOC106987487
gene id: 32536:LOC106987487
uniprot id: A0A6J0A927
uniprot id: A0A6J2AHC0
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

32536:PPP1R9A
gene id: 32536:PPP1R9A
uniprot id: A0A6J2AD26
names: Subcellular Location Annotation
messages: cytoskeleton

32536:RBM22
gene id: 32536:RBM22
uniprot id: A0A6J2AXX5
names: Similarity
messages: Belongs to the SLT11 family.

32536:TOMM5
gene id: 32536:TOMM5
uniprot id: A0A6J0A1Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:IRAK1BP1
gene id: 32536:IRAK1BP1
uniprot id: A0A6I9ZLG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

32536:CCT8
gene id: 32536:CCT8
uniprot id: A0A6I9ZZP1
uniprot id: A0A6I9ZZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

32536:LOC106982894
gene id: 32536:LOC106982894
uniprot id: A0A6J0A0R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NAALAD2
gene id: 32536:NAALAD2
uniprot id: A0A6J0A4V6
uniprot id: A0A6J0A4W1
uniprot id: A0A6J1XTT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

32536:CLIP1
gene id: 32536:CLIP1
uniprot id: A0A6J1Y4W0
names: Subcellular Location Annotation
messages: cytoskeleton

32536:SEPTIN9
gene id: 32536:SEPTIN9
uniprot id: A0A6J1YSG9
uniprot id: A0A6J1YTX8
uniprot id: A0A6J1YUB4
uniprot id: A0A6J1YVQ6
uniprot id: A0A6J1YVR1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

32536:LOC113593305
gene id: 32536:LOC113593305
uniprot id: A0A6J1XKJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3. May form a heterodimer with CTU2/NCS2.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

32536:CHD1L
gene id: 32536:CHD1L
uniprot id: A0A6J1YQ30
uniprot id: A0A6J1YRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

32536:ALKAL2
gene id: 32536:ALKAL2
uniprot id: A0A6J2AU34
uniprot id: A0A6J2AUJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

32536:SRRT
gene id: 32536:SRRT
uniprot id: A0A6J1XZ12
uniprot id: A0A6J1XZ17
uniprot id: A0A6J1XZ65
uniprot id: A0A6J1XZ89
uniprot id: A0A6J1XZ94
uniprot id: A0A6J1XZJ6
uniprot id: A0A6J1Y041
names: Similarity
messages: Belongs to the ARS2 family.

32536:NEK9
gene id: 32536:NEK9
uniprot id: A0A6J1ZXW5
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

32536:KCNMB3
gene id: 32536:KCNMB3
uniprot id: A0A6J1ZII6
names: Subcellular Location Annotation
messages: Membrane

32536:RPP30
gene id: 32536:RPP30
uniprot id: A0A6I9ZCT5
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

32536:PGC
gene id: 32536:PGC
uniprot id: A0A6I9ZTH7
names: Similarity
messages: Belongs to the peptidase A1 family.

32536:KCNV2
gene id: 32536:KCNV2
uniprot id: A0A6J1XXB1
names: Subcellular Location Annotation
messages: Membrane

32536:PIGS
gene id: 32536:PIGS
uniprot id: A0A6J0A4I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106966127
gene id: 32536:LOC106966127
uniprot id: A0A6I9ZGA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PLCG2
gene id: 32536:PLCG2
uniprot id: A0A6J2ARZ2
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

32536:LOC106973006
gene id: 32536:LOC106973006
uniprot id: A0A0A0Y3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:CDH8
gene id: 32536:CDH8
uniprot id: A0A6J2AQU9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:PIH1D1
gene id: 32536:PIH1D1
uniprot id: A0A6J0ABN6
names: Similarity
messages: Belongs to the PIH1 family.

32536:LOC106986223
gene id: 32536:LOC106986223
uniprot id: A0A6J0A4M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LDAH
gene id: 32536:LDAH
uniprot id: A0A6I9ZT14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

32536:PAXBP1
gene id: 32536:PAXBP1
uniprot id: A0A6I9ZC80
names: Similarity
messages: Belongs to the GCF family.

32536:TMEM183A
gene id: 32536:TMEM183A
uniprot id: A0A6J2AL58
uniprot id: A0A6J2AMC4
uniprot id: A0A6J2APQ2
uniprot id: A0A6J2AQ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

32536:SNX17
gene id: 32536:SNX17
uniprot id: A0A6J1XA09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

32536:UBE4B
gene id: 32536:UBE4B
uniprot id: A0A6J1ZFM9
uniprot id: A0A6J1ZFZ0
uniprot id: A0A6J1ZJ19
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm
messages: The U-box domain is required for the ubiquitin protein ligase activity.
messages: Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases. Also functions as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase. Mediates 'Lys-48'-linked polyubiquitination of substrates.

32536:AMER1
gene id: 32536:AMER1
uniprot id: A0A6J1YWV3
names: Similarity
messages: Belongs to the Amer family.

32536:LOC106982878
gene id: 32536:LOC106982878
uniprot id: A0A6J0A3J9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

32536:SMAD9
gene id: 32536:SMAD9
uniprot id: A0A6J1ZSI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

32536:CDC45
gene id: 32536:CDC45
uniprot id: A0A6J0A1Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

32536:PSMC3
gene id: 32536:PSMC3
uniprot id: A0A6J2AEX5
names: Similarity
messages: Belongs to the AAA ATPase family.

32536:ALOX5AP
gene id: 32536:ALOX5AP
uniprot id: A0A6J0A402
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106979912
gene id: 32536:LOC106979912
uniprot id: A0A6J0A0V8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

32536:MBP
gene id: 32536:MBP
uniprot id: A0A6J2A595
uniprot id: A0A6J2A5D1
uniprot id: A0A6J2A8Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

32536:FZD1
gene id: 32536:FZD1
uniprot id: A0A6J2ACK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:RNF5
gene id: 32536:RNF5
uniprot id: A0A6J0A4F1
uniprot id: A0A6J1Z9Y0
names: Domain
names: Function
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion membrane
messages: The RING-type zinc finger domain is responsible for E3 ligase activity.

32536:F2
gene id: 32536:F2
uniprot id: A0A6J2AJ48
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

32536:SPRTN
gene id: 32536:SPRTN
uniprot id: A0A6J1YCI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

32536:BLOC1S3
gene id: 32536:BLOC1S3
uniprot id: A0A6I9ZSS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

32536:LOC106988637
gene id: 32536:LOC106988637
uniprot id: A0A6J0AAJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:METAP2
gene id: 32536:METAP2
uniprot id: A0A6I9ZM18
uniprot id: A0A6I9ZQB3
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

32536:LOC106986613
gene id: 32536:LOC106986613
uniprot id: A0A6J1XE98
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

32536:ATAD2B
gene id: 32536:ATAD2B
uniprot id: A0A6J1X6Y6
uniprot id: A0A6J1X9U5
names: Similarity
messages: Belongs to the AAA ATPase family.

32536:PIK3CB
gene id: 32536:PIK3CB
uniprot id: A0A6J1ZKD6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:PDP2
gene id: 32536:PDP2
uniprot id: A0A6I9ZJ32
names: Similarity
messages: Belongs to the PP2C family.

32536:PDS5B
gene id: 32536:PDS5B
uniprot id: A0A6J1ZSD4
uniprot id: A0A6J1ZSS2
uniprot id: A0A6J1ZTH5
uniprot id: A0A6J1ZV21
uniprot id: A0A6J1ZWF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDS5 family.
messages: Nucleus

32536:TPPP2
gene id: 32536:TPPP2
uniprot id: A0A6I9ZNU4
uniprot id: A0A6J1ZUQ8
names: Similarity
messages: Belongs to the TPPP family.

32536:NDUFV2
gene id: 32536:NDUFV2
uniprot id: A0A6I9ZFG6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

32536:ELK4
gene id: 32536:ELK4
uniprot id: A0A6I9ZRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:RPL32
gene id: 32536:RPL32
uniprot id: A0A6I9ZXB9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

32536:NAB2
gene id: 32536:NAB2
uniprot id: A0A6J2ABE7
uniprot id: A0A6J2ABN4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

32536:SLC46A2
gene id: 32536:SLC46A2
uniprot id: A0A6J1XDT3
uniprot id: A0A6J1XDU5
names: Subcellular Location Annotation
messages: Membrane

32536:HRH4
gene id: 32536:HRH4
uniprot id: A0A6I9ZYV9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:SLC25A5
gene id: 32536:SLC25A5
uniprot id: A0A6J1YZ64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

32536:ENTPD5
gene id: 32536:ENTPD5
uniprot id: A0A6I9ZRT3
uniprot id: A0A6J1ZXT2
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

32536:HCST
gene id: 32536:HCST
uniprot id: A0A6I9ZQE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

32536:ASTE1
gene id: 32536:ASTE1
uniprot id: A0A6J1ZJU2
names: Similarity
messages: Belongs to the asteroid family.

32536:LOC106969838
gene id: 32536:LOC106969838
uniprot id: A0A6I9ZLZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MMP24
gene id: 32536:MMP24
uniprot id: A0A6I9ZPE7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

32536:QRFPR
gene id: 32536:QRFPR
uniprot id: A0A6I9ZWX1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:FAM187A
gene id: 32536:FAM187A
uniprot id: A0A6J0AA01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

32536:MFRP
gene id: 32536:MFRP
uniprot id: A0A6J0A5A1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PPA1
gene id: 32536:PPA1
uniprot id: A0A6J1ZLL0
names: Similarity
messages: Belongs to the PPase family.

32536:UROS
gene id: 32536:UROS
uniprot id: A0A6J1ZNS1
uniprot id: A0A6J1ZNS5
uniprot id: A0A6J1ZPT7
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

32536:LOC106986233
gene id: 32536:LOC106986233
uniprot id: A0A6J0A7K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CNIH1
gene id: 32536:CNIH1
uniprot id: A0A6J1ZY69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

32536:FGF10
gene id: 32536:FGF10
uniprot id: A0A6I9ZG69
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:ELOVL1
gene id: 32536:ELOVL1
uniprot id: A0A6I9ZML2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

32536:GABRQ
gene id: 32536:GABRQ
uniprot id: A0A6J1YVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:NRG4
gene id: 32536:NRG4
uniprot id: A0A6J2A1P6
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:OLFM4
gene id: 32536:OLFM4
uniprot id: A0A6J0A8Y4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CBR3
gene id: 32536:CBR3
uniprot id: A0A6I9ZHJ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

32536:TMEM94
gene id: 32536:TMEM94
uniprot id: A0A6J1YSH6
uniprot id: A0A6J1YSI3
uniprot id: A0A6J1YSI6
uniprot id: A0A6J1YSI8
uniprot id: A0A6J1YSJ1
uniprot id: A0A6J1YSJ6
uniprot id: A0A6J1YSJ7
uniprot id: A0A6J1YTZ3
uniprot id: A0A6J1YTZ8
uniprot id: A0A6J1YUC7
uniprot id: A0A6J1YUD4
uniprot id: A0A6J1YVR6
uniprot id: A0A6J1YVS2
names: Subcellular Location Annotation
messages: Membrane

32536:NEURL2
gene id: 32536:NEURL2
uniprot id: A0A6I9ZG53
names: Subcellular Location Annotation
messages: Cytoplasm

32536:SRM
gene id: 32536:SRM
uniprot id: A0A6J1ZHU9
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

32536:SEMA5B
gene id: 32536:SEMA5B
uniprot id: A0A6J1ZH39
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SLC35A1
gene id: 32536:SLC35A1
uniprot id: A0A6I9ZKY9
uniprot id: A0A6I9ZMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:KBTBD8
gene id: 32536:KBTBD8
uniprot id: A0A6J1XRG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

32536:LOC106987568
gene id: 32536:LOC106987568
uniprot id: A0A6J0A6L3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GABRA4
gene id: 32536:GABRA4
uniprot id: A0A6I9ZQQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:LOC106966855
gene id: 32536:LOC106966855
uniprot id: A0A6I9ZCR8
uniprot id: A0A6J1ZPS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

32536:CCNC
gene id: 32536:CCNC
uniprot id: A0A6J1Z6Y8
uniprot id: A0A6J1Z8A5
names: Similarity
messages: Belongs to the cyclin family.

32536:GRM3
gene id: 32536:GRM3
uniprot id: A0A6J2ACC1
uniprot id: A0A6J2AGP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

32536:CBFA2T2
gene id: 32536:CBFA2T2
uniprot id: A0A6J2A738
names: Similarity
messages: Belongs to the CBFA2T family.

32536:NUBP1
gene id: 32536:NUBP1
uniprot id: A0A6J0A8G8
uniprot id: A0A6J0AC53
uniprot id: A0A6J1Y2A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106978164
gene id: 32536:LOC106978164
uniprot id: A0A6I9ZYK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

32536:ULK3
gene id: 32536:ULK3
uniprot id: A0A6J2A2B1
uniprot id: A0A6J2A4E6
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:BABAM1
gene id: 32536:BABAM1
uniprot id: A0A6I9ZGA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

32536:CARTPT
gene id: 32536:CARTPT
uniprot id: A0A6I9ZVT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

32536:ELL2
gene id: 32536:ELL2
uniprot id: A0A6J1XLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

32536:SIN3A
gene id: 32536:SIN3A
uniprot id: A0A6J2A2E1
names: Subcellular Location Annotation
messages: Nucleus

32536:PPIL3
gene id: 32536:PPIL3
uniprot id: A0A6J0AAR7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:CCNT2
gene id: 32536:CCNT2
uniprot id: A0A6I9ZRK4
uniprot id: A0A6J1Z2K4
uniprot id: A0A6J1Z2W7
uniprot id: A0A6J1Z4M1
names: Similarity
messages: Belongs to the cyclin family.

32536:SLC30A4
gene id: 32536:SLC30A4
uniprot id: A0A6J2A0K8
uniprot id: A0A6J2A3K7
uniprot id: A0A6J2A3L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

32536:AMD1
gene id: 32536:AMD1
uniprot id: A0A6J1Z7Y4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
messages: Heterotetramer of two alpha and two beta chains.

32536:RUVBL1
gene id: 32536:RUVBL1
uniprot id: A0A6J0A867
uniprot id: A0A6J1YLI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

32536:GNG5
gene id: 32536:GNG5
uniprot id: A0A6J1ZDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:PTBP1
gene id: 32536:PTBP1
uniprot id: A0A6J1YKJ5
uniprot id: A0A6J1YL45
names: Subcellular Location Annotation
messages: Nucleus

32536:ZKSCAN5
gene id: 32536:ZKSCAN5
uniprot id: A0A6I9ZYJ7
uniprot id: A0A6J0A1R9
uniprot id: A0A6J0A2C5
names: Subcellular Location Annotation
messages: Nucleus

32536:RTF2
gene id: 32536:RTF2
uniprot id: A0A6I9ZJC9
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

32536:DOCK4
gene id: 32536:DOCK4
uniprot id: A0A6J2AMM3
uniprot id: A0A6J2ANZ2
uniprot id: A0A6J2ARB3
uniprot id: A0A6J2ART2
names: Similarity
messages: Belongs to the DOCK family.

32536:SNX33
gene id: 32536:SNX33
uniprot id: A0A6I9ZWZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

32536:RUNX1
gene id: 32536:RUNX1
uniprot id: A0A6J1XXY3
uniprot id: A0A6J1XY44
uniprot id: A0A6J1XYC8
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

32536:DDX28
gene id: 32536:DDX28
uniprot id: A0A6I9ZPK7
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:MAPK8
gene id: 32536:MAPK8
uniprot id: A0A6J1ZLE7
uniprot id: A0A6J1ZLQ3
uniprot id: A0A6J1ZNU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

32536:LOC106968047
gene id: 32536:LOC106968047
uniprot id: A0A6I9ZJI5
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

32536:LOC113596236
gene id: 32536:LOC113596236
uniprot id: A0A6J1YJ02
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

32536:DNAJC27
gene id: 32536:DNAJC27
uniprot id: A0A6I9ZFT8
uniprot id: A0A6I9ZJ17
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).

32536:LOC106986230
gene id: 32536:LOC106986230
uniprot id: A0A6J0A4P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MPI
gene id: 32536:MPI
uniprot id: A0A6J0A046
uniprot id: A0A6J0A0A0
uniprot id: A0A6J2A1J9
uniprot id: A0A6J2A591
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

32536:TRAPPC5
gene id: 32536:TRAPPC5
uniprot id: A0A6J1YNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: cis-Golgi network

32536:ALDH3A2
gene id: 32536:ALDH3A2
uniprot id: A0A6J1YEG5
uniprot id: A0A6J1YFA1
uniprot id: A0A6J1YFT3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:GLYR1
gene id: 32536:GLYR1
uniprot id: A0A6J1Y2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIBADH-related family. NP60 subfamily.
messages: Chromosome

32536:FAM168B
gene id: 32536:FAM168B
uniprot id: A0A6J1Z358
uniprot id: A0A6J1Z4G1
names: Similarity
messages: Belongs to the FAM168 family.

32536:S100A8
gene id: 32536:S100A8
uniprot id: A0A6J0A680
names: Similarity
messages: Belongs to the S-100 family.

32536:KCNE5
gene id: 32536:KCNE5
uniprot id: A0A6J1YZQ5
names: Similarity
messages: Belongs to the potassium channel KCNE family.

32536:SETDB2
gene id: 32536:SETDB2
uniprot id: A0A6I9ZPA2
uniprot id: A0A6J1ZSS1
uniprot id: A0A6J1ZVC8
names: Subcellular Location Annotation
messages: Chromosome

32536:SLA2
gene id: 32536:SLA2
uniprot id: A0A6I9ZVQ0
names: Subcellular Location Annotation
messages: Cytoplasm

32536:LOC106969810
gene id: 32536:LOC106969810
uniprot id: A0A6J1YVU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LGR6
gene id: 32536:LGR6
uniprot id: A0A6J2AL19
uniprot id: A0A6J2APL8
uniprot id: A0A6J2AQ37
names: Subcellular Location Annotation
messages: Membrane

32536:TMTC3
gene id: 32536:TMTC3
uniprot id: A0A6I9ZWF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

32536:PCBD1
gene id: 32536:PCBD1
uniprot id: A0A6J1ZKU6
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

32536:SLC8A1
gene id: 32536:SLC8A1
uniprot id: A0A6J0A4U1
uniprot id: A0A6J0A7E0
uniprot id: A0A6J1XAB5
uniprot id: A0A6J1XAB7
uniprot id: A0A6J1XAB8
uniprot id: A0A6J1XAB9
uniprot id: A0A6J1XAC0
uniprot id: A0A6J1XAC1
uniprot id: A0A6J1XAC5
uniprot id: A0A6J1XAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

32536:KNG1
gene id: 32536:KNG1
uniprot id: A0A6J1ZIZ8
uniprot id: A0A6J1ZL92
names: Subcellular Location Annotation
messages: extracellular space

32536:NDUFB9
gene id: 32536:NDUFB9
uniprot id: A0A6J0A554
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

32536:SORCS1
gene id: 32536:SORCS1
uniprot id: A0A6J0A335
uniprot id: A0A6J1ZMT7
uniprot id: A0A6J1ZNY2
uniprot id: A0A6J1ZRM3
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

32536:ACAP2
gene id: 32536:ACAP2
uniprot id: A0A6J1ZHK4
uniprot id: A0A6J1ZHW3
uniprot id: A0A6J1ZIT6
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

32536:CELF4
gene id: 32536:CELF4
uniprot id: A0A6J2A4A1
uniprot id: A0A6J2A4A5
uniprot id: A0A6J2A4A9
uniprot id: A0A6J2A4B0
uniprot id: A0A6J2A4B3
uniprot id: A0A6J2A4B4
uniprot id: A0A6J2A4B9
uniprot id: A0A6J2A4C2
uniprot id: A0A6J2A4C3
uniprot id: A0A6J2A4C4
uniprot id: A0A6J2A4C8
uniprot id: A0A6J2A4C9
uniprot id: A0A6J2A4D3
uniprot id: A0A6J2A4D4
uniprot id: A0A6J2A4D7
uniprot id: A0A6J2A4D9
uniprot id: A0A6J2A4E4
uniprot id: A0A6J2A4E8
uniprot id: A0A6J2A5C3
uniprot id: A0A6J2A5C9
uniprot id: A0A6J2A5D4
uniprot id: A0A6J2A5D7
uniprot id: A0A6J2A5E2
uniprot id: A0A6J2A5E7
uniprot id: A0A6J2A5F6
uniprot id: A0A6J2A5G0
uniprot id: A0A6J2A5G4
uniprot id: A0A6J2A7X6
uniprot id: A0A6J2A7Y8
uniprot id: A0A6J2A7Z3
uniprot id: A0A6J2A7Z8
uniprot id: A0A6J2A803
uniprot id: A0A6J2A807
uniprot id: A0A6J2A812
uniprot id: A0A6J2A821
uniprot id: A0A6J2A8B1
uniprot id: A0A6J2A8B5
uniprot id: A0A6J2A8C0
uniprot id: A0A6J2A8C7
uniprot id: A0A6J2A8D1
uniprot id: A0A6J2A8D4
uniprot id: A0A6J2A8D9
uniprot id: A0A6J2A8E4
uniprot id: A0A6J2A8E5
uniprot id: A0A6J2A8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Nucleus

32536:PHF1
gene id: 32536:PHF1
uniprot id: A0A6J1ZBX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

32536:TNFSF4
gene id: 32536:TNFSF4
uniprot id: A0A6J0A104
names: Similarity
messages: Belongs to the tumor necrosis factor family.

32536:LOC106986275
gene id: 32536:LOC106986275
uniprot id: A0A6J0A7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NIPA2
gene id: 32536:NIPA2
uniprot id: A0A6J0A8B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

32536:LOC106977792
gene id: 32536:LOC106977792
uniprot id: A0A6I9ZT55
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:EXT1
gene id: 32536:EXT1
uniprot id: A0A6I9ZPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:CYFIP1
gene id: 32536:CYFIP1
uniprot id: A0A6J2A1Q9
uniprot id: A0A6J2A5H5
names: Similarity
messages: Belongs to the CYFIP family.

32536:HYAL3
gene id: 32536:HYAL3
uniprot id: A0A6I9ZZX7
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

32536:LOC106982803
gene id: 32536:LOC106982803
uniprot id: A0A6J0A0W7
names: Similarity
messages: Belongs to the PP3/GlyCAM-1 family.

32536:P4HA2
gene id: 32536:P4HA2
uniprot id: A0A6I9ZLG7
uniprot id: A0A6J2ARP3
uniprot id: A0A6J2AT84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

32536:GALR1
gene id: 32536:GALR1
uniprot id: A0A6J2A693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

32536:MYO6
gene id: 32536:MYO6
uniprot id: A0A6J1Z6P5
uniprot id: A0A6J1Z824
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus
messages: ruffle membrane
messages: trans-Golgi network membrane

32536:IRX5
gene id: 32536:IRX5
uniprot id: A0A6J1Y5T6
uniprot id: A0A6J1Y6H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

32536:UCHL3
gene id: 32536:UCHL3
uniprot id: A0A6J1ZW21
names: Similarity
messages: Belongs to the peptidase C12 family.

32536:CDK5
gene id: 32536:CDK5
uniprot id: A0A6J1YR46
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:NDRG1
gene id: 32536:NDRG1
uniprot id: A0A6J1ZU69
names: Similarity
messages: Belongs to the NDRG family.

32536:MNS1
gene id: 32536:MNS1
uniprot id: A0A6J2A088
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

32536:LOC106974065
gene id: 32536:LOC106974065
uniprot id: A0A6J1Y122
uniprot id: A0A6J1Y1F4
uniprot id: A0A6J1Y2L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

32536:PON1
gene id: 32536:PON1
uniprot id: A0A6I9ZK34
uniprot id: A0A6I9ZLV3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.
messages: Glycosylated.

32536:TMSB10
gene id: 32536:TMSB10
uniprot id: A0A6J2AHL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

32536:ASPHD1
gene id: 32536:ASPHD1
uniprot id: A0A6I9ZIG1
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

32536:LOC106969859
gene id: 32536:LOC106969859
uniprot id: A0A6I9ZM06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SLC40A1
gene id: 32536:SLC40A1
uniprot id: A0A6J0A0K0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

32536:LOC106986184
gene id: 32536:LOC106986184
uniprot id: A0A6J0A4J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:KIF4A
gene id: 32536:KIF4A
uniprot id: A0A6J1YWF5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:XRCC4
gene id: 32536:XRCC4
uniprot id: A0A6I9ZWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus

32536:DBX1
gene id: 32536:DBX1
uniprot id: A0A6J2AI46
names: Subcellular Location Annotation
messages: Nucleus

32536:SOD1
gene id: 32536:SOD1
uniprot id: A0A6J1XYM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

32536:TPR
gene id: 32536:TPR
uniprot id: A0A6I9ZD42
uniprot id: A0A6I9ZG47
names: Similarity
messages: Belongs to the TPR family.

32536:A4GALT
gene id: 32536:A4GALT
uniprot id: A0A6I9ZEX8
uniprot id: A0A6J2A968
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

32536:SUPT6H
gene id: 32536:SUPT6H
uniprot id: A0A6J1XCU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

32536:IPO9
gene id: 32536:IPO9
uniprot id: A0A6J2APJ7
names: Subcellular Location Annotation
messages: Cytoplasm

32536:DMRTC2
gene id: 32536:DMRTC2
uniprot id: A0A6J0A6R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

32536:EMX2
gene id: 32536:EMX2
uniprot id: A0A6J1ZPG9
names: Subcellular Location Annotation
messages: Nucleus

32536:SPOCK2
gene id: 32536:SPOCK2
uniprot id: A0A6J1ZLQ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106987356
gene id: 32536:LOC106987356
uniprot id: A0A6J0A9Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RHBDF1
gene id: 32536:RHBDF1
uniprot id: A0A6J1Y3L4
uniprot id: A0A6J1Y4C0
uniprot id: A0A6J1Y4F6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

32536:NF2
gene id: 32536:NF2
uniprot id: A0A6J1YNF7
uniprot id: A0A6J1YNH3
uniprot id: A0A6J1YPU3
uniprot id: A0A6J1YQ75
uniprot id: A0A6J1YRF7
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

32536:COMT
gene id: 32536:COMT
uniprot id: A0A6J1YK83
uniprot id: A0A6J1YK88
uniprot id: A0A6J1YMU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
messages: Cell membrane

32536:DNMT1
gene id: 32536:DNMT1
uniprot id: A0A6J1YMA2
uniprot id: A0A6J1YNL5
uniprot id: A0A6J1YNX7
uniprot id: A0A6J1YQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

32536:LOC106974652
gene id: 32536:LOC106974652
uniprot id: A0A6I9ZTD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TMED5
gene id: 32536:TMED5
uniprot id: A0A6I9ZJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

32536:H1-2
gene id: 32536:H1-2
uniprot id: A0A6J1XU42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

32536:SERPINB9
gene id: 32536:SERPINB9
uniprot id: A0A6J1XTT9
uniprot id: A0A6J1XUA2
names: Similarity
messages: Belongs to the serpin family.
messages: Belongs to the serpin family. Ov-serpin subfamily.

32536:LOC106989536
gene id: 32536:LOC106989536
uniprot id: A0A6J0ABG2
names: Caution
names: Function
names: Similarity
messages: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TSSK6
gene id: 32536:TSSK6
uniprot id: A0A6I9ZL00
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:HGD
gene id: 32536:HGD
uniprot id: A0A6I9ZV57
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

32536:TRMT1L
gene id: 32536:TRMT1L
uniprot id: A0A6J2AJH6
uniprot id: A0A6J2AL46
uniprot id: A0A6J2ANM1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

32536:TFF2
gene id: 32536:TFF2
uniprot id: A0A6J0A6N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106966044
gene id: 32536:LOC106966044
uniprot id: A0A6J1XSM5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ATP1B3
gene id: 32536:ATP1B3
uniprot id: A0A6J1ZMQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

32536:TFR2
gene id: 32536:TFR2
uniprot id: A0A6J1XZ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

32536:ACSF3
gene id: 32536:ACSF3
uniprot id: A0A6J2ASC8
uniprot id: A0A6J2AV58
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

32536:MTO1
gene id: 32536:MTO1
uniprot id: A0A6I9ZX70
uniprot id: A0A6J0A177
uniprot id: A0A6J0A1F8
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

32536:NAPEPLD
gene id: 32536:NAPEPLD
uniprot id: A0A6J2AC66
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPE-PLD family.
messages: Binds 2 zinc divalent cations per subunit.
messages: Homodimer. Bile acids promote the assembly of inactive monomers into an active dimer and enable catalysis.
messages: Nucleus envelope

32536:INPP5A
gene id: 32536:INPP5A
uniprot id: A0A6J1ZP18
uniprot id: A0A6J1ZPC5
uniprot id: A0A6J1ZSW0
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

32536:PRDM16
gene id: 32536:PRDM16
uniprot id: A0A6J1ZGG5
uniprot id: A0A6J1ZIH9
uniprot id: A0A6J1ZJL1
names: Subcellular Location Annotation
messages: Nucleus

32536:HS2ST1
gene id: 32536:HS2ST1
uniprot id: A0A6I9ZLV0
uniprot id: A0A6I9ZQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:GTF3C5
gene id: 32536:GTF3C5
uniprot id: A0A6J1XFR3
names: Subcellular Location Annotation
messages: Nucleus

32536:TSPAN6
gene id: 32536:TSPAN6
uniprot id: A0A6J1YYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:OTUB1
gene id: 32536:OTUB1
uniprot id: A0A6J1Y7Z5
names: Similarity
messages: Belongs to the peptidase C65 family.

32536:ABRAXAS2
gene id: 32536:ABRAXAS2
uniprot id: A0A6I9ZMY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abro1 subfamily.
messages: Nucleus
messages: spindle pole

32536:COPZ1
gene id: 32536:COPZ1
uniprot id: A0A6J0A8T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

32536:SCARB1
gene id: 32536:SCARB1
uniprot id: A0A6J1Y4U8
uniprot id: A0A6J1Y516
uniprot id: A0A6J1Y6S9
names: Similarity
messages: Belongs to the CD36 family.

32536:LTBR
gene id: 32536:LTBR
uniprot id: A0A6J2AJD6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:MGST2
gene id: 32536:MGST2
uniprot id: A0A6I9ZW16
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:PPIC
gene id: 32536:PPIC
uniprot id: A0A6J2ARH3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:SNF8
gene id: 32536:SNF8
uniprot id: A0A6J0A1I6
uniprot id: A0A6J1XBE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

32536:XPC
gene id: 32536:XPC
uniprot id: A0A6I9ZVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

32536:KCTD13
gene id: 32536:KCTD13
uniprot id: A0A6I9ZGT2
names: Similarity
messages: Belongs to the BACURD family.

32536:CISD2
gene id: 32536:CISD2
uniprot id: A0A6J0A608
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CISD protein family. CISD2 subfamily.
messages: Binds 1 [2Fe-2S] cluster.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Mitochondrion outer membrane
messages: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.

32536:RBP2
gene id: 32536:RBP2
uniprot id: A0A6J1ZJH6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

32536:CSTB
gene id: 32536:CSTB
uniprot id: A0A6J1XXQ8
names: Similarity
messages: Belongs to the cystatin family.

32536:WDFY1
gene id: 32536:WDFY1
uniprot id: A0A6J1YJB6
uniprot id: A0A6J1YJD3
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

32536:AHDC1
gene id: 32536:AHDC1
uniprot id: A0A6J1ZGD2
names: Subcellular Location Annotation
messages: Nucleus

32536:NCR3
gene id: 32536:NCR3
uniprot id: A0A6J0A5E3
uniprot id: A0A6J1ZB01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natural cytotoxicity receptor (NCR) family.
messages: Cell membrane
messages: Homodimer in the unliganted form. Interacts with CD3Z. Interacts with and is activated by binding to NCR3LG1. Interacts with and is activated by binding to BAG6.
messages: Membrane

32536:DPY19L2
gene id: 32536:DPY19L2
uniprot id: A0A6I9ZK11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

32536:CENPL
gene id: 32536:CENPL
uniprot id: A0A6I9ZEW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

32536:NPM1
gene id: 32536:NPM1
uniprot id: A0A6I9ZM37
uniprot id: A0A6I9ZQC4
names: Similarity
messages: Belongs to the nucleoplasmin family.

32536:CACNG4
gene id: 32536:CACNG4
uniprot id: A0A6J1YF44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.

32536:TAT
gene id: 32536:TAT
uniprot id: A0A6J0A6Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

32536:A2ML1
gene id: 32536:A2ML1
uniprot id: A0A6J2AKQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

32536:NMI
gene id: 32536:NMI
uniprot id: A0A6J1Z3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

32536:SLC13A3
gene id: 32536:SLC13A3
uniprot id: A0A6J2A896
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

32536:LOC106973933
gene id: 32536:LOC106973933
uniprot id: A0A6I9ZPE1
uniprot id: A0A6I9ZT86
uniprot id: A0A6J2AB29
names: Similarity
messages: Belongs to the CBP3 family.

32536:METAP1D
gene id: 32536:METAP1D
uniprot id: A0A6J1Z3E6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

32536:DYRK3
gene id: 32536:DYRK3
uniprot id: A0A6J0A326
uniprot id: A0A6J2AK59
uniprot id: A0A6J2ALX5
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

32536:GALNT17
gene id: 32536:GALNT17
uniprot id: A0A6I9ZLA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:LOC106966037
gene id: 32536:LOC106966037
uniprot id: A0A6I9ZEI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106980756
gene id: 32536:LOC106980756
uniprot id: A0A6J0A240
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SMIM19
gene id: 32536:SMIM19
uniprot id: A0A6J2AFL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

32536:EXOC5
gene id: 32536:EXOC5
uniprot id: A0A6J1ZZQ6
names: Similarity
messages: Belongs to the SEC10 family.

32536:PLPPR1
gene id: 32536:PLPPR1
uniprot id: A0A6I9ZNF9
uniprot id: A0A6J1XSB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

32536:CAD
gene id: 32536:CAD
uniprot id: A0A6J1X769
uniprot id: A0A6J1X9Z8
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

32536:TM4SF20
gene id: 32536:TM4SF20
uniprot id: A0A6I9ZM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

32536:POMK
gene id: 32536:POMK
uniprot id: A0A6J0A9H9
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

32536:SAMD8
gene id: 32536:SAMD8
uniprot id: A0A6I9ZJM2
uniprot id: A0A6J1ZKW5
uniprot id: A0A6J1ZM10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

32536:VPS51
gene id: 32536:VPS51
uniprot id: A0A6J1Y8C7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS51 family.
messages: Component of the Golgi-associated retrograde protein (GARP) complex. Component of the endosome-associated retrograde protein (EARP) complex.
messages: Endosome
messages: Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling.
messages: Recycling endosome
messages: trans-Golgi network

32536:LOC106984984
gene id: 32536:LOC106984984
uniprot id: A0A0A0Y2C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:DPAGT1
gene id: 32536:DPAGT1
uniprot id: A0A6J0A285
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:WEE1
gene id: 32536:WEE1
uniprot id: A0A6I9ZX37
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

32536:SLC41A2
gene id: 32536:SLC41A2
uniprot id: A0A6I9ZLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

32536:HPX
gene id: 32536:HPX
uniprot id: A0A6J0A1Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hemopexin family.
messages: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
messages: Secreted

32536:TTC36
gene id: 32536:TTC36
uniprot id: A0A6J1XIX9
names: Similarity
messages: Belongs to the TTC36 family.

32536:ITK
gene id: 32536:ITK
uniprot id: A0A6I9ZIP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:MYF5
gene id: 32536:MYF5
uniprot id: A0A6I9ZIC2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

32536:LOC106983516
gene id: 32536:LOC106983516
uniprot id: A0A6J0A1U8
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

32536:IL3
gene id: 32536:IL3
uniprot id: A0A6J2AWD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-3 family.
messages: Secreted

32536:NR2E3
gene id: 32536:NR2E3
uniprot id: A0A6J2A0Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:G6PC3
gene id: 32536:G6PC3
uniprot id: A0A6J1YKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

32536:SLC13A2
gene id: 32536:SLC13A2
uniprot id: A0A6J1XCT0
uniprot id: A0A6J1XCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

32536:SDAD1
gene id: 32536:SDAD1
uniprot id: A0A6J1ZD68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

32536:USP5
gene id: 32536:USP5
uniprot id: A0A6J2ANL5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:AGA
gene id: 32536:AGA
uniprot id: A0A6J2AU52
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

32536:SLC2A1
gene id: 32536:SLC2A1
uniprot id: A0A6J1ZEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane
messages: Photoreceptor inner segment

32536:PTPRA
gene id: 32536:PTPRA
uniprot id: A0A6J2A7H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 4 subfamily.
messages: Cell membrane
messages: Membrane

32536:AGRP
gene id: 32536:AGRP
uniprot id: A0A6J2ATU5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:VPS37C
gene id: 32536:VPS37C
uniprot id: A0A6I9ZTB1
uniprot id: A0A6J1Y9N1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

32536:BTC
gene id: 32536:BTC
uniprot id: A0A6J0A2Z7
uniprot id: A0A6J1Z9A1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:COG2
gene id: 32536:COG2
uniprot id: A0A6J1YCT2
uniprot id: A0A6J1YCT7
uniprot id: A0A6J1YCV6
uniprot id: A0A6J1YDJ6
uniprot id: A0A6J1YE65
uniprot id: A0A6J1YEW3
names: Similarity
messages: Belongs to the COG2 family.

32536:DDX43
gene id: 32536:DDX43
uniprot id: A0A6I9ZY35
uniprot id: A0A6J1Z6R5
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:LOC106973067
gene id: 32536:LOC106973067
uniprot id: A0A6I9ZS46
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

32536:LOC106973301
gene id: 32536:LOC106973301
uniprot id: A0A6I9ZQ44
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

32536:MMP27
gene id: 32536:MMP27
uniprot id: A0A6I9ZUU2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

32536:TMEM218
gene id: 32536:TMEM218
uniprot id: A0A6I9ZRL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

32536:LTBP1
gene id: 32536:LTBP1
uniprot id: A0A6J1X6R5
uniprot id: A0A6J1X6S0
uniprot id: A0A6J1XA76
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:LOC106986868
gene id: 32536:LOC106986868
uniprot id: A0A6J0A849
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PPEF1
gene id: 32536:PPEF1
uniprot id: A0A6J1Z011
names: Similarity
messages: Belongs to the PPP phosphatase family.

32536:BRMS1L
gene id: 32536:BRMS1L
uniprot id: A0A6I9ZCC9
uniprot id: A0A6I9ZFG3
names: Subcellular Location Annotation
messages: Nucleus

32536:ELAC1
gene id: 32536:ELAC1
uniprot id: A0A6J2A8R7
names: Subunit
messages: Homodimer.

32536:SLC15A5
gene id: 32536:SLC15A5
uniprot id: A0A6J1XG23
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

32536:TATDN3
gene id: 32536:TATDN3
uniprot id: A0A6I9ZCM3
uniprot id: A0A6I9ZE15
uniprot id: A0A6J2AP04
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

32536:TBXT
gene id: 32536:TBXT
uniprot id: A0A6J1Z435
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:CAVIN1
gene id: 32536:CAVIN1
uniprot id: A0A6J1YJZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

32536:PLP1
gene id: 32536:PLP1
uniprot id: A0A6I9ZYY5
uniprot id: A0A6I9ZZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

32536:RPS14
gene id: 32536:RPS14
uniprot id: A0A6J0A7G3
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

32536:SLC20A2
gene id: 32536:SLC20A2
uniprot id: A0A6J2AFZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane
messages: Sodium-phosphate symporter.

32536:LOC106965832
gene id: 32536:LOC106965832
uniprot id: A0A6I9ZFW9
uniprot id: A0A6I9ZFY7
names: Similarity
messages: Belongs to the cytochrome P450 family.

32536:MYORG
gene id: 32536:MYORG
uniprot id: A0A6J1XRM9
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

32536:BARHL1
gene id: 32536:BARHL1
uniprot id: A0A6J1XFL5
names: Subcellular Location Annotation
messages: Nucleus

32536:SKP1
gene id: 32536:SKP1
uniprot id: A0A6J2AW25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

32536:ELF3
gene id: 32536:ELF3
uniprot id: A0A6I9ZN42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

32536:CNRIP1
gene id: 32536:CNRIP1
uniprot id: A0A6I9ZIU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.

32536:SLC18A1
gene id: 32536:SLC18A1
uniprot id: A0A6J2AXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Membrane
messages: secretory vesicle membrane
messages: synaptic vesicle membrane

32536:NNAT
gene id: 32536:NNAT
uniprot id: A0A6J2A7M3
uniprot id: A0A6J2A8J7
uniprot id: A0A6J2ABF8
names: Similarity
messages: Belongs to the neuronatin family.

32536:CYRIB
gene id: 32536:CYRIB
uniprot id: A0A6I9ZVI4
uniprot id: A0A6J1ZQM2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

32536:PADI1
gene id: 32536:PADI1
uniprot id: A0A6J1ZGA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

32536:SFRP2
gene id: 32536:SFRP2
uniprot id: A0A6J2A201
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106973143
gene id: 32536:LOC106973143
uniprot id: A0A6J2A5C8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

32536:CCNJL
gene id: 32536:CCNJL
uniprot id: A0A6I9ZIN6
names: Similarity
messages: Belongs to the cyclin family.

32536:SUSD2
gene id: 32536:SUSD2
uniprot id: A0A6J1Y4Q1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SNX32
gene id: 32536:SNX32
uniprot id: A0A6J1Y8Q9
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

32536:CRYBA1
gene id: 32536:CRYBA1
uniprot id: A0A6J0A3Z6
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:PDCL3
gene id: 32536:PDCL3
uniprot id: A0A6I9ZFL0
names: Similarity
messages: Belongs to the phosducin family.

32536:IER2
gene id: 32536:IER2
uniprot id: A0A6J1YNZ1
names: Similarity
messages: Belongs to the IER family.

32536:ZSCAN20
gene id: 32536:ZSCAN20
uniprot id: A0A6I9ZNC3
uniprot id: A0A6J1ZDM7
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

32536:CSGALNACT1
gene id: 32536:CSGALNACT1
uniprot id: A0A6I9ZYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

32536:PTN
gene id: 32536:PTN
uniprot id: A0A6I9ZUV0
uniprot id: A0A6J2ASJ2
names: Similarity
messages: Belongs to the pleiotrophin family.

32536:CA8
gene id: 32536:CA8
uniprot id: A0A6J1Y1A4
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

32536:LOC106986219
gene id: 32536:LOC106986219
uniprot id: A0A6J0A785
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:L1CAM
gene id: 32536:L1CAM
uniprot id: A0A6J1YYE4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

32536:GJA1
gene id: 32536:GJA1
uniprot id: A0A6I9ZKZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with SGSM3 (By similarity). Interacts with RIC1/CIP150 (By similarity). Interacts with CNST and CSNK1D (By similarity). Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain). Interacts (not ubiquitinated) with UBQLN4 (via UBA domain) (By similarity). Interacts with NOV. Interacts with TMEM65.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Endoplasmic reticulum
messages: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

32536:FKBP4
gene id: 32536:FKBP4
uniprot id: A0A6J2AIL9
names: Subcellular Location Annotation
messages: Mitochondrion
messages: cytoskeleton
messages: cytosol

32536:KPNA2
gene id: 32536:KPNA2
uniprot id: A0A6J1YFZ8
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

32536:SATB1
gene id: 32536:SATB1
uniprot id: A0A6J1ZJN8
uniprot id: A0A6J1ZKV1
uniprot id: A0A6J1ZM27
uniprot id: A0A6J1ZND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

32536:LOC106976326
gene id: 32536:LOC106976326
uniprot id: A0A6J1XUK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:ABCA1
gene id: 32536:ABCA1
uniprot id: A0A6I9ZVS7
uniprot id: A0A6J1XDH4
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106971690
gene id: 32536:LOC106971690
uniprot id: A0A6I9ZLC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

32536:CNNM1
gene id: 32536:CNNM1
uniprot id: A0A6J1ZMA0
uniprot id: A0A6J1ZMJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

32536:SEMA4F
gene id: 32536:SEMA4F
uniprot id: A0A6J2ADB1
uniprot id: A0A6J2ADQ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ARRB2
gene id: 32536:ARRB2
uniprot id: A0A6J1YEV6
uniprot id: A0A6J1YG78
names: Similarity
messages: Belongs to the arrestin family.

32536:MBOAT1
gene id: 32536:MBOAT1
uniprot id: A0A6J1XUS3
names: Subcellular Location Annotation
messages: Membrane

32536:CCT4
gene id: 32536:CCT4
uniprot id: A0A6J2AIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

32536:S100A11
gene id: 32536:S100A11
uniprot id: A0A6J1Z4J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the S-100 family.
messages: Facilitates the differentiation and the cornification of keratinocytes.
messages: Homodimer; disulfide-linked.

32536:PDE3A
gene id: 32536:PDE3A
uniprot id: A0A6I9ZSC9
uniprot id: A0A6J1XG97
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:CCR7
gene id: 32536:CCR7
uniprot id: A0A6J0A1V1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:CAMSAP1
gene id: 32536:CAMSAP1
uniprot id: A0A6J1YR35
uniprot id: A0A6J1YU93
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

32536:DDX49
gene id: 32536:DDX49
uniprot id: A0A6I9ZKP9
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:IDO1
gene id: 32536:IDO1
uniprot id: A0A6I9ZYU3
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

32536:CA3
gene id: 32536:CA3
uniprot id: A0A6J0A3H4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

32536:TLR10
gene id: 32536:TLR10
uniprot id: A0A6I9ZZX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

32536:LOC106968313
gene id: 32536:LOC106968313
uniprot id: A0A6J2AND7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

32536:GLYATL2
gene id: 32536:GLYATL2
uniprot id: A0A6J0A808
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

32536:LCTL
gene id: 32536:LCTL
uniprot id: A0A6J2A0R0
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

32536:TBX5
gene id: 32536:TBX5
uniprot id: A0A6J1Y4N6
uniprot id: A0A6J1Y4S6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:LOC106989821
gene id: 32536:LOC106989821
uniprot id: A0A6J2ABP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RNF167
gene id: 32536:RNF167
uniprot id: A0A6J1YEL5
names: Subcellular Location Annotation
messages: Membrane

32536:SPIN1
gene id: 32536:SPIN1
uniprot id: A0A6J1XX33
names: Similarity
messages: Belongs to the SPIN/STSY family.

32536:DGUOK
gene id: 32536:DGUOK
uniprot id: A0A6J2ADE8
uniprot id: A0A6J2AHU7
names: Similarity
messages: Belongs to the DCK/DGK family.

32536:VPS26A
gene id: 32536:VPS26A
uniprot id: A0A6J1ZKF1
uniprot id: A0A6J1ZLJ6
names: Similarity
messages: Belongs to the VPS26 family.

32536:CALCR
gene id: 32536:CALCR
uniprot id: A0A6I9ZH77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

32536:SELENOI
gene id: 32536:SELENOI
uniprot id: A0A6I9ZIX7
uniprot id: A0A6J1XA19
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

32536:BUD31
gene id: 32536:BUD31
uniprot id: A0A6J0A2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

32536:LOC106985146
gene id: 32536:LOC106985146
uniprot id: A0A6J0A3I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:FN1
gene id: 32536:FN1
uniprot id: A0A6I9ZHF9
uniprot id: A0A6I9ZHG4
uniprot id: A0A6I9ZJ08
uniprot id: A0A6I9ZJ13
uniprot id: A0A6I9ZKC4
uniprot id: A0A6I9ZKD0
uniprot id: A0A6I9ZM21
uniprot id: A0A6I9ZM25
uniprot id: A0A6I9ZMG9
uniprot id: A0A6I9ZMH4
uniprot id: A0A6J1YPW6
uniprot id: A0A6J1YQ08
names: Function
messages: Secreted by contracting muscle, induces liver autophagy, a degradative pathway for nutrient mobilization and damage removal, and systemic insulin sensitization via hepatic ITGA5:ITGB1 integrin receptor signaling.

32536:LOC106983648
gene id: 32536:LOC106983648
uniprot id: A0A6J0A1Z1
uniprot id: A0A6J0A5N0
uniprot id: A0A6J1ZL25
uniprot id: A0A6J1ZLW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C14A family.
messages: Belongs to the phospholipase A2 family.
messages: Secreted

32536:B3GALT4
gene id: 32536:B3GALT4
uniprot id: A0A6J1Z8G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:NUDC
gene id: 32536:NUDC
uniprot id: A0A6J1ZEK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

32536:IFNG
gene id: 32536:IFNG
uniprot id: D1GA52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer. Interacts with IFNGR1 (via extracellular domain); this interaction promotes IFNGR1 dimerization.
messages: Secreted
messages: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL. Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation.

32536:CHMP2A
gene id: 32536:CHMP2A
uniprot id: A0A6J0A9Q5
names: Similarity
messages: Belongs to the SNF7 family.

32536:TAS2R1
gene id: 32536:TAS2R1
uniprot id: A0A6I9ZJ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:CEP57L1
gene id: 32536:CEP57L1
uniprot id: A0A6I9ZIS2
uniprot id: A0A6J1Z6T1
names: Similarity
messages: Belongs to the translokin family.

32536:MRPS25
gene id: 32536:MRPS25
uniprot id: A0A6I9ZZC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

32536:SRPX
gene id: 32536:SRPX
uniprot id: A0A6J1YXI5
uniprot id: A0A6J1YYU1
uniprot id: A0A6J1YZM9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:AMFR
gene id: 32536:AMFR
uniprot id: A0A6J1Y5V4
names: Subcellular Location Annotation
messages: Membrane

32536:FMNL2
gene id: 32536:FMNL2
uniprot id: A0A6J1Z2F8
uniprot id: A0A6J1Z2G3
uniprot id: A0A6J1Z3H1
uniprot id: A0A6J1Z5M0
names: Similarity
messages: Belongs to the formin homology family.

32536:KIF23
gene id: 32536:KIF23
uniprot id: A0A6J2A151
uniprot id: A0A6J2A1X7
uniprot id: A0A6J2A4V6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:HMGN3
gene id: 32536:HMGN3
uniprot id: A0A6J1Z6M9
uniprot id: A0A6J1Z7E4
uniprot id: A0A6J1Z810
uniprot id: A0A6J1ZA47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

32536:PELO
gene id: 32536:PELO
uniprot id: A0A6I9ZR42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. In the Pelota-HBS1L complex, pelo recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel.
messages: Cytoplasm

32536:UBALD2
gene id: 32536:UBALD2
uniprot id: A0A6J1YUV8
uniprot id: A0A6J1YWA4
names: Similarity
messages: Belongs to the UBALD family.

32536:ZSCAN22
gene id: 32536:ZSCAN22
uniprot id: A0A6J0ABE7
names: Subcellular Location Annotation
messages: Nucleus

32536:HSFX4
gene id: 32536:HSFX4
uniprot id: A0A6J1YW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

32536:UCP1
gene id: 32536:UCP1
uniprot id: A0A6I9ZW08
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: May undergo ubiquitin-mediated proteasomal degradation.
messages: Membrane
messages: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
messages: Mitochondrion inner membrane

32536:PRMT7
gene id: 32536:PRMT7
uniprot id: A0A6J2APB9
uniprot id: A0A6J2APC5
uniprot id: A0A6J2APT5
uniprot id: A0A6J2ARB1
uniprot id: A0A6J2ATK0
uniprot id: A0A6J2AU20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

32536:VGLL3
gene id: 32536:VGLL3
uniprot id: A0A6I9ZLI0
uniprot id: A0A6J2ATM8
uniprot id: A0A6J2AVN3
uniprot id: A0A6J2AY37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

32536:LOC106989769
gene id: 32536:LOC106989769
uniprot id: A0A6J0ABL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:HRH3
gene id: 32536:HRH3
uniprot id: A0A6J1YCS5
uniprot id: A0A6J1YDG3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:CAP2
gene id: 32536:CAP2
uniprot id: A0A6J1XUN7
uniprot id: A0A6J1XUT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

32536:ALDOA
gene id: 32536:ALDOA
uniprot id: A0A6I9ZGN7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

32536:DCC
gene id: 32536:DCC
uniprot id: A0A6J2A4P9
uniprot id: A0A6J2A8E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

32536:LTB
gene id: 32536:LTB
uniprot id: A0A6J1Z9M6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

32536:DHX58
gene id: 32536:DHX58
uniprot id: A0A6J1YIF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

32536:CD74
gene id: 32536:CD74
uniprot id: A0A6J0A6D0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:GRB2
gene id: 32536:GRB2
uniprot id: A0A6J1YV27
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

32536:GUCY1B1
gene id: 32536:GUCY1B1
uniprot id: A0A6J2A1S7
uniprot id: A0A6J2A2K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

32536:ARSD
gene id: 32536:ARSD
uniprot id: A0A6J0A396
uniprot id: A0A6J0A3N8
uniprot id: A0A6J1YW02
names: Similarity
messages: Belongs to the sulfatase family.

32536:SPATS2
gene id: 32536:SPATS2
uniprot id: A0A6J1XHA1
uniprot id: A0A6J1XHE0
names: Similarity
messages: Belongs to the SPATS2 family.

32536:KIF11
gene id: 32536:KIF11
uniprot id: A0A6I9ZFW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
messages: spindle pole

32536:UBN2
gene id: 32536:UBN2
uniprot id: A0A6J2APX0
names: Similarity
messages: Belongs to the ubinuclein family.

32536:LOC106972122
gene id: 32536:LOC106972122
uniprot id: A0A6I9ZQS1
names: Similarity
messages: Belongs to the cytochrome b5 family.

32536:HBQ1
gene id: 32536:HBQ1
uniprot id: A0A6J1Y1J8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

32536:GALNT2
gene id: 32536:GALNT2
uniprot id: A0A6J1YCM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:TNS3
gene id: 32536:TNS3
uniprot id: A0A6J1Y9Y2
uniprot id: A0A6J1Y9Y4
uniprot id: A0A6J1YAK8
uniprot id: A0A6J1YB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

32536:LMX1B
gene id: 32536:LMX1B
uniprot id: A0A6J1XEM9
uniprot id: A0A6J1XEN0
names: Subcellular Location Annotation
messages: Nucleus

32536:CNOT8
gene id: 32536:CNOT8
uniprot id: A0A6I9ZFI3
uniprot id: A0A6I9ZIQ8
uniprot id: A0A6J2AZ32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

32536:LRRC51
gene id: 32536:LRRC51
uniprot id: A0A6I9ZNX2
names: Subcellular Location Annotation
messages: Cytoplasm

32536:HSF1
gene id: 32536:HSF1
uniprot id: A0A6J1ZPH1
uniprot id: A0A6J1ZPT5
uniprot id: A0A6J1ZS20
uniprot id: A0A6J1ZTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

32536:EDC4
gene id: 32536:EDC4
uniprot id: A0A6J2AP76
uniprot id: A0A6J2APP7
uniprot id: A0A6J2ATF1
uniprot id: A0A6J2ATW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EDC4 family.
messages: P-body

32536:GPR171
gene id: 32536:GPR171
uniprot id: A0A6I9ZU79
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:AKAP5
gene id: 32536:AKAP5
uniprot id: A0A6J1ZVY1
names: Subcellular Location Annotation
messages: Membrane

32536:ME2
gene id: 32536:ME2
uniprot id: A0A6J2A5Q5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

32536:TAFA3
gene id: 32536:TAFA3
uniprot id: A0A6I9ZL97
uniprot id: A0A6J1ZAM6
names: Similarity
messages: Belongs to the TAFA family.

32536:EFS
gene id: 32536:EFS
uniprot id: A0A6J0AB72
names: Similarity
messages: Belongs to the CAS family.

32536:LOC106979532
gene id: 32536:LOC106979532
uniprot id: A0A6I9ZZI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:UPP1
gene id: 32536:UPP1
uniprot id: A0A6J1Y9U6
uniprot id: A0A6J1YAY9
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

32536:PPP1CC
gene id: 32536:PPP1CC
uniprot id: A0A6J1Y4D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: nucleolus
messages: nucleoplasm

32536:ADH4
gene id: 32536:ADH4
uniprot id: A0A6I9ZKH3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

32536:MFN1
gene id: 32536:MFN1
uniprot id: A0A6I9ZSB4
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

32536:PRDX5
gene id: 32536:PRDX5
uniprot id: A0A6J1Y940
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

32536:ME3
gene id: 32536:ME3
uniprot id: A0A6J1XTA8
uniprot id: A0A6J1XTR4
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

32536:WASF1
gene id: 32536:WASF1
uniprot id: A0A6J1Z5Z3
uniprot id: A0A6J1Z6Q2
uniprot id: A0A6J1Z9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

32536:SLC25A13
gene id: 32536:SLC25A13
uniprot id: A0A6I9ZK39
uniprot id: A0A6J2AD45
uniprot id: A0A6J2AE42
uniprot id: A0A6J2AGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

32536:PSEN2
gene id: 32536:PSEN2
uniprot id: A0A6J1YAC0
uniprot id: A0A6J1YAZ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: The PAL motif is required for normal active site conformation.

32536:PIK3CA
gene id: 32536:PIK3CA
uniprot id: A0A6J1ZI66
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:VTA1
gene id: 32536:VTA1
uniprot id: A0A6I9ZFU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

32536:NAALADL1
gene id: 32536:NAALADL1
uniprot id: A0A6J1YA84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

32536:LOC106978685
gene id: 32536:LOC106978685
uniprot id: A0A6I9ZUS4
uniprot id: A0A6I9ZVZ6
names: Similarity
messages: Belongs to the TACO1 family.

32536:CASKIN2
gene id: 32536:CASKIN2
uniprot id: A0A6J1YSK1
uniprot id: A0A6J1YSK2
uniprot id: A0A6J1YVT3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

32536:SARM1
gene id: 32536:SARM1
uniprot id: A0A6J1XCS1
uniprot id: A0A6J1XCT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARM1 family.
messages: axon

32536:GALNTL5
gene id: 32536:GALNTL5
uniprot id: A0A6J1YSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Membrane

32536:RNF39
gene id: 32536:RNF39
uniprot id: A0A6J1YSI9
names: Subcellular Location Annotation
messages: Cytoplasm

32536:SNRPA
gene id: 32536:SNRPA
uniprot id: A0A6I9ZXB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

32536:RNASE12
gene id: 32536:RNASE12
uniprot id: A0A6J1ZUP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

32536:FAM166C
gene id: 32536:FAM166C
uniprot id: A0A6I9ZJ22
names: Similarity
messages: Belongs to the CIMIP2 family.

32536:LOC106978695
gene id: 32536:LOC106978695
uniprot id: A0A6I9ZUT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

32536:CCNJ
gene id: 32536:CCNJ
uniprot id: A0A6J1ZN35
names: Similarity
messages: Belongs to the cyclin family.

32536:CDH6
gene id: 32536:CDH6
uniprot id: A0A6J2AKU2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:EIF2B5
gene id: 32536:EIF2B5
uniprot id: A0A6J0A5T5
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

32536:POLD1
gene id: 32536:POLD1
uniprot id: A0A6J1XK42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

32536:TCP1
gene id: 32536:TCP1
uniprot id: A0A6I9ZG18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: centrosome

32536:GTF2E2
gene id: 32536:GTF2E2
uniprot id: A0A6J2ASX7
uniprot id: A0A6J2AUW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

32536:PARK7
gene id: 32536:PARK7
uniprot id: A0A6J0A057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

32536:TUBGCP3
gene id: 32536:TUBGCP3
uniprot id: A0A6J1ZUE9
uniprot id: A0A6J1ZV57
uniprot id: A0A6J1ZWQ2
uniprot id: A0A6J1ZY52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

32536:PEX7
gene id: 32536:PEX7
uniprot id: A0A6J0A214
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Peroxisome matrix
messages: cytosol

32536:DNAJB14
gene id: 32536:DNAJB14
uniprot id: A0A6J1ZIB7
uniprot id: A0A6J1ZJJ2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:S100Z
gene id: 32536:S100Z
uniprot id: A0A6J1XSR1
names: Similarity
messages: Belongs to the S-100 family.

32536:LOC106976546
gene id: 32536:LOC106976546
uniprot id: A0A6I9ZVZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SGSM3
gene id: 32536:SGSM3
uniprot id: A0A6J2A990
uniprot id: A0A6J2AAE1
uniprot id: A0A6J2AD63
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

32536:LOC106969812
gene id: 32536:LOC106969812
uniprot id: A0A6I9ZLH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CD4
gene id: 32536:CD4
uniprot id: A0A6J2AN56
names: Subcellular Location Annotation
messages: Cell membrane

32536:RPL36A
gene id: 32536:RPL36A
uniprot id: A0A6J0A5B2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

32536:LSM14B
gene id: 32536:LSM14B
uniprot id: A0A6J1YBI7
uniprot id: A0A6J1YC59
uniprot id: A0A6J1YCT0
names: Similarity
messages: Belongs to the LSM14 family.

32536:NAE1
gene id: 32536:NAE1
uniprot id: A0A6I9ZKM8
uniprot id: A0A6J2AQX5
uniprot id: A0A6J2AT56
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

32536:CYSLTR2
gene id: 32536:CYSLTR2
uniprot id: A0A6I9ZNB1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:MMP23B
gene id: 32536:MMP23B
uniprot id: A0A6J1ZGM7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CLCN2
gene id: 32536:CLCN2
uniprot id: A0A6J1ZHW9
uniprot id: A0A6J1ZJ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

32536:ROR2
gene id: 32536:ROR2
uniprot id: A0A6J1XWK3
uniprot id: A0A6J1XXI0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:SBF2
gene id: 32536:SBF2
uniprot id: A0A6J2AG95
uniprot id: A0A6J2AGQ8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

32536:MAP4K5
gene id: 32536:MAP4K5
uniprot id: A0A6J1ZVL9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

32536:LOC106981183
gene id: 32536:LOC106981183
uniprot id: A0A6J1XZL6
uniprot id: A0A6J1Y0I0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: myofibril

32536:STK35
gene id: 32536:STK35
uniprot id: A0A6J2AAH1
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:DPM2
gene id: 32536:DPM2
uniprot id: A0A6I9ZC05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

32536:CNR1
gene id: 32536:CNR1
uniprot id: A0A6I9ZP40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

32536:LOC106970687
gene id: 32536:LOC106970687
uniprot id: A0A6I9ZNK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Basal cell membrane
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

32536:MEA1
gene id: 32536:MEA1
uniprot id: A0A6I9ZPK6
uniprot id: A0A6I9ZR98
names: Function
messages: May play an important role in spermatogenesis and/or testis development.

32536:FPR2
gene id: 32536:FPR2
uniprot id: A0A6J1XKF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Membrane

32536:LOC106974897
gene id: 32536:LOC106974897
uniprot id: A0A6I9ZNZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NOX3
gene id: 32536:NOX3
uniprot id: A0A6J0A598
names: Subcellular Location Annotation
messages: Membrane

32536:KIAA2013
gene id: 32536:KIAA2013
uniprot id: A0A6J1ZGK9
uniprot id: A0A6J1ZHR2
names: Subcellular Location Annotation
messages: Membrane

32536:TRIQK
gene id: 32536:TRIQK
uniprot id: A0A6J1ZV98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:TMEM163
gene id: 32536:TMEM163
uniprot id: A0A6J1Z4N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Membrane
messages: synaptic vesicle membrane

32536:GGTA1
gene id: 32536:GGTA1
uniprot id: A0A6J0A8W1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Membrane

32536:TGFA
gene id: 32536:TGFA
uniprot id: A0A6J2ADQ8
uniprot id: A0A6J2AE23
uniprot id: A0A6J2AF23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC113592407
gene id: 32536:LOC113592407
uniprot id: A0A6J1Y4I9
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

32536:PRDM1
gene id: 32536:PRDM1
uniprot id: A0A6J1Z6W1
uniprot id: A0A6J1Z9L1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

32536:ITGA2B
gene id: 32536:ITGA2B
uniprot id: A0A6I9ZN72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

32536:GFAP
gene id: 32536:GFAP
uniprot id: A0A6J1YIF6
uniprot id: A0A6J1YKR6
names: Similarity
messages: Belongs to the intermediate filament family.

32536:FAM131C
gene id: 32536:FAM131C
uniprot id: A0A6J1ZGD6
names: Similarity
messages: Belongs to the FAM131 family.

32536:LOC106976619
gene id: 32536:LOC106976619
uniprot id: A0A6I9ZT04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CRYBB1
gene id: 32536:CRYBB1
uniprot id: A0A6J1YN99
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:ABHD3
gene id: 32536:ABHD3
uniprot id: A0A6I9ZHB0
uniprot id: A0A6I9ZIS5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

32536:PSMD12
gene id: 32536:PSMD12
uniprot id: A0A6I9ZPM6
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

32536:NECAP1
gene id: 32536:NECAP1
uniprot id: A0A6J2AKP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

32536:RABGGTA
gene id: 32536:RABGGTA
uniprot id: A0A6J1ZUM4
uniprot id: A0A6J1ZXF9
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.

32536:COQ8B
gene id: 32536:COQ8B
uniprot id: A0A6J1Y7P9
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

32536:GLS2
gene id: 32536:GLS2
uniprot id: A0A6J0A5N3
uniprot id: A0A6J0A5T1
uniprot id: A0A6J0A8J0
uniprot id: A0A6J2ABH6
names: Similarity
messages: Belongs to the glutaminase family.

32536:PABPC1
gene id: 32536:PABPC1
uniprot id: A0A6J1ZR79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

32536:SDHAF1
gene id: 32536:SDHAF1
uniprot id: A0A6I9ZTI3
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

32536:CDX4
gene id: 32536:CDX4
uniprot id: A0A6J0A5G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

32536:PGAP2
gene id: 32536:PGAP2
uniprot id: A0A6J1XSQ4
uniprot id: A0A6J1XSR0
uniprot id: A0A6J1XSS0
uniprot id: A0A6J1XSU4
uniprot id: A0A6J1XSZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PGAP2 family.
messages: Interacts with PGAP2IP.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

32536:KIF24
gene id: 32536:KIF24
uniprot id: A0A6I9ZV21
uniprot id: A0A6J1XRM4
uniprot id: A0A6J1XRS2
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106976596
gene id: 32536:LOC106976596
uniprot id: A0A6I9ZSY7
names: Subcellular Location Annotation
messages: Membrane

32536:NIPSNAP2
gene id: 32536:NIPSNAP2
uniprot id: A0A6J1XYJ6
names: Similarity
messages: Belongs to the NipSnap family.

32536:NSG1
gene id: 32536:NSG1
uniprot id: A0A6J1XFA0
names: Similarity
messages: Belongs to the NSG family.

32536:STAT2
gene id: 32536:STAT2
uniprot id: A0A6J0A989
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

32536:ZNF483
gene id: 32536:ZNF483
uniprot id: A0A6I9ZJV1
names: Subcellular Location Annotation
messages: Nucleus

32536:VIL1
gene id: 32536:VIL1
uniprot id: A0A6J1YPF7
names: Similarity
messages: Belongs to the villin/gelsolin family.

32536:ANAPC10
gene id: 32536:ANAPC10
uniprot id: A0A6J0A1Y9
uniprot id: A0A6J1ZZK7
uniprot id: A0A6J2A2J9
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

32536:GATA6
gene id: 32536:GATA6
uniprot id: A0A6J2A3P0
names: Subcellular Location Annotation
messages: Nucleus

32536:CCDC167
gene id: 32536:CCDC167
uniprot id: A0A6I9ZPE8
names: Subcellular Location Annotation
messages: Membrane

32536:NKD1
gene id: 32536:NKD1
uniprot id: A0A6J1Y5X3
uniprot id: A0A6J1Y7N5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm

32536:IDH3G
gene id: 32536:IDH3G
uniprot id: A0A6J1YVD3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

32536:OSTC
gene id: 32536:OSTC
uniprot id: A0A6J0A1V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

32536:PGAP1
gene id: 32536:PGAP1
uniprot id: A0A6J1YXH8
uniprot id: A0A6J1YXM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:VPS52
gene id: 32536:VPS52
uniprot id: A0A6I9ZS62
names: Similarity
messages: Belongs to the VPS52 family.

32536:LOC106967305
gene id: 32536:LOC106967305
uniprot id: A0A6I9ZEY3
uniprot id: A0A6I9ZGG9
uniprot id: A0A6I9ZGH3
uniprot id: A0A6J1Y1V8
uniprot id: A0A6J1Y234
uniprot id: A0A6J1Y240
uniprot id: A0A6J1Y2F4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

32536:DDR1
gene id: 32536:DDR1
uniprot id: A0A6J1YTY4
names: Subcellular Location Annotation
messages: Membrane

32536:HOOK3
gene id: 32536:HOOK3
uniprot id: A0A6J2AD18
uniprot id: A0A6J2AG93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

32536:DUSP2
gene id: 32536:DUSP2
uniprot id: A0A6J1XAG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

32536:SMARCD2
gene id: 32536:SMARCD2
uniprot id: A0A6J1YHW5
names: Similarity
messages: Belongs to the SMARCD family.

32536:FAM151A
gene id: 32536:FAM151A
uniprot id: A0A6J1ZEZ6
names: Similarity
messages: Belongs to the FAM151 family.

32536:EIF3H
gene id: 32536:EIF3H
uniprot id: A0A6I9ZRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with RNF139; the interaction leads to protein translation inhibitions in a ubiquitination-dependent manner.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

32536:TCIRG1
gene id: 32536:TCIRG1
uniprot id: A0A6J1Y8R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

32536:RNFT1
gene id: 32536:RNFT1
uniprot id: A0A6I9ZL50
uniprot id: A0A6I9ZPB1
names: Subcellular Location Annotation
messages: Membrane

32536:TMEM186
gene id: 32536:TMEM186
uniprot id: A0A6J1Y470
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

32536:SLC2A3
gene id: 32536:SLC2A3
uniprot id: A0A6I9ZF64
uniprot id: A0A6J2AJM6
uniprot id: A0A6J2AN91
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

32536:LOC106974825
gene id: 32536:LOC106974825
uniprot id: A0A6J1XSD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:SLC6A4
gene id: 32536:SLC6A4
uniprot id: A0A6I9ZIE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Synapse
messages: focal adhesion
messages: neuron projection

32536:ERG28
gene id: 32536:ERG28
uniprot id: A0A6I9ZN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:GUF1
gene id: 32536:GUF1
uniprot id: A0A6J0A7P0
uniprot id: A0A6J1Z400
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

32536:BASP1
gene id: 32536:BASP1
uniprot id: A0A6J2APQ4
names: Similarity
messages: Belongs to the BASP1 family.

32536:DOHH
gene id: 32536:DOHH
uniprot id: A0A6J1YMI2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.

32536:WEE2
gene id: 32536:WEE2
uniprot id: A0A6J2ANL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

32536:S100B
gene id: 32536:S100B
uniprot id: A0A6J1XXE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

32536:HPDL
gene id: 32536:HPDL
uniprot id: A0A6I9ZM42
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

32536:SERPINB6
gene id: 32536:SERPINB6
uniprot id: A0A6I9ZSA3
names: Similarity
messages: Belongs to the serpin family.

32536:WASF3
gene id: 32536:WASF3
uniprot id: A0A6J1ZSL0
uniprot id: A0A6J1ZW82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

32536:SPIRE2
gene id: 32536:SPIRE2
uniprot id: A0A6J2AQJ1
uniprot id: A0A6J2AR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

32536:SV2B
gene id: 32536:SV2B
uniprot id: A0A6J2A1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

32536:FZD2
gene id: 32536:FZD2
uniprot id: A0A6I9ZTK6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:RANBP17
gene id: 32536:RANBP17
uniprot id: A0A6J1XCC1
uniprot id: A0A6J1XCD3
uniprot id: A0A6J1XCE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

32536:THRB
gene id: 32536:THRB
uniprot id: A0A6J1XVY9
uniprot id: A0A6J1XVZ7
uniprot id: A0A6J1XWC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:TBC1D24
gene id: 32536:TBC1D24
uniprot id: A0A6J1Y2X6
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse

32536:POLR3G
gene id: 32536:POLR3G
uniprot id: A0A6J1XNQ6
uniprot id: A0A6J1XNZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

32536:LOC106988586
gene id: 32536:LOC106988586
uniprot id: A0A6J0A821
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:LOC106978874
gene id: 32536:LOC106978874
uniprot id: A0A6I9ZZF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C1 family.
messages: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
messages: Secreted

32536:LOC106977531
gene id: 32536:LOC106977531
uniprot id: A0A6J1ZE32
uniprot id: A0A6J1ZEF3
uniprot id: A0A6J1ZF70
uniprot id: A0A6J1ZG83
uniprot id: A0A6J1ZG88
uniprot id: A0A6J1ZG90
uniprot id: A0A6J1ZHC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

32536:SLC6A20
gene id: 32536:SLC6A20
uniprot id: A0A6J1XPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

32536:SUMO2
gene id: 32536:SUMO2
uniprot id: A0A6J0A6T2
uniprot id: A0A6J1YTG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

32536:LOC106971493
gene id: 32536:LOC106971493
uniprot id: A0A6I9ZJG6
names: Similarity
messages: Belongs to the SPATA31 family.

32536:MRPS7
gene id: 32536:MRPS7
uniprot id: A0A6J0A6W2
uniprot id: A0A6J0A9G7
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

32536:DDX53
gene id: 32536:DDX53
uniprot id: A0A6J1YZY2
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:HS3ST1
gene id: 32536:HS3ST1
uniprot id: A0A6J1XJF1
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

32536:ATIC
gene id: 32536:ATIC
uniprot id: A0A6J1YRH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PurH family.
messages: cytosol

32536:SLC25A25
gene id: 32536:SLC25A25
uniprot id: A0A6I9ZDD6
uniprot id: A0A6J1XEV2
uniprot id: A0A6J1XEV3
uniprot id: A0A6J1XEW1
uniprot id: A0A6J1XEW5
uniprot id: A0A6J1XEX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

32536:TNFRSF21
gene id: 32536:TNFRSF21
uniprot id: A0A6J1Z840
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:EPHA3
gene id: 32536:EPHA3
uniprot id: A0A6J2ATN1
uniprot id: A0A6J2AY42
names: Subcellular Location Annotation
messages: Membrane

32536:PYCR1
gene id: 32536:PYCR1
uniprot id: A0A6J1YVL8
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

32536:LOC106970107
gene id: 32536:LOC106970107
uniprot id: A0A6I9ZME1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

32536:LOC106972168
gene id: 32536:LOC106972168
uniprot id: A0A6I9ZLZ5
uniprot id: A0A6I9ZQV9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

32536:P2RX3
gene id: 32536:P2RX3
uniprot id: A0A6J1Y8Q3
uniprot id: A0A6J1YAK4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

32536:CD40
gene id: 32536:CD40
uniprot id: A0A6I9ZIX5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:DAPK2
gene id: 32536:DAPK2
uniprot id: A0A6J0A673
uniprot id: A0A6J2A3E2
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:GDPD5
gene id: 32536:GDPD5
uniprot id: A0A6I9ZY19
uniprot id: A0A6I9ZY98
uniprot id: A0A6J1XSX6
uniprot id: A0A6J1XT96
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

32536:UTS2B
gene id: 32536:UTS2B
uniprot id: A0A6J1ZJ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

32536:AMDHD1
gene id: 32536:AMDHD1
uniprot id: A0A6J2AAA0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

32536:CRHBP
gene id: 32536:CRHBP
uniprot id: A0A6J1XSQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

32536:ARMC9
gene id: 32536:ARMC9
uniprot id: A0A6J1YFR0
uniprot id: A0A6J1YFU0
uniprot id: A0A6J1YFU6
uniprot id: A0A6J1YGJ9
uniprot id: A0A6J1YH51
uniprot id: A0A6J1YHU3
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

32536:LOC106969340
gene id: 32536:LOC106969340
uniprot id: A0A6I9ZHW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:UTP25
gene id: 32536:UTP25
uniprot id: A0A6I9ZZE7
uniprot id: A0A6J2AKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

32536:MTMR3
gene id: 32536:MTMR3
uniprot id: A0A6J1YMX6
uniprot id: A0A6J1YMX9
uniprot id: A0A6J1YMY4
uniprot id: A0A6J1YMZ6
uniprot id: A0A6J1YN01
uniprot id: A0A6J1YPB8
uniprot id: A0A6J1YPC2
uniprot id: A0A6J1YPP0
uniprot id: A0A6J1YQX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm
messages: Membrane

32536:ADAMTS8
gene id: 32536:ADAMTS8
uniprot id: A0A6J1XJU2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:TYRP1
gene id: 32536:TYRP1
uniprot id: A0A6I9ZTC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

32536:LOC106986180
gene id: 32536:LOC106986180
uniprot id: A0A6J0A4K8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ARMC1
gene id: 32536:ARMC1
uniprot id: A0A6J0A7U4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

32536:SST
gene id: 32536:SST
uniprot id: A0A6I9ZEP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

32536:SLC16A7
gene id: 32536:SLC16A7
uniprot id: A0A6J2AB72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

32536:PSMB3
gene id: 32536:PSMB3
uniprot id: A0A6J0A0V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:NDUFB6
gene id: 32536:NDUFB6
uniprot id: A0A6I9ZS27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

32536:RBX1
gene id: 32536:RBX1
uniprot id: A0A6J2ADI9
names: Similarity
messages: Belongs to the RING-box family.

32536:FGFR1OP2
gene id: 32536:FGFR1OP2
uniprot id: A0A6I9ZK69
uniprot id: A0A6I9ZKG0
names: Similarity
messages: Belongs to the SIKE family.

32536:LOC106984563
gene id: 32536:LOC106984563
uniprot id: A0A6J0A2T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

32536:NKX1-2
gene id: 32536:NKX1-2
uniprot id: A0A6J1ZPQ0
names: Subcellular Location Annotation
messages: Nucleus

32536:FAHD1
gene id: 32536:FAHD1
uniprot id: A0A6J0A4I0
names: Similarity
messages: Belongs to the FAH family.

32536:TRIM67
gene id: 32536:TRIM67
uniprot id: A0A6J1YDV8
names: Subcellular Location Annotation
messages: cytoskeleton

32536:FXR2
gene id: 32536:FXR2
uniprot id: A0A6J1YDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasmic ribonucleoprotein granule
messages: Postsynapse
messages: Synapse

32536:CCL26
gene id: 32536:CCL26
uniprot id: A0A6J0A1R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:LOC106982898
gene id: 32536:LOC106982898
uniprot id: A0A6J0A453
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RPL38
gene id: 32536:RPL38
uniprot id: A0A6J1YF68
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

32536:EXTL2
gene id: 32536:EXTL2
uniprot id: A0A6I9ZWA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:LOC106966099
gene id: 32536:LOC106966099
uniprot id: A0A6I9ZEN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NUP98
gene id: 32536:NUP98
uniprot id: A0A6J1XSE4
uniprot id: A0A6J1XSH1
uniprot id: A0A6J1XSP9
uniprot id: A0A6J1XSS9
uniprot id: A0A6J1XSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

32536:ARFGEF1
gene id: 32536:ARFGEF1
uniprot id: A0A6J1Y193
uniprot id: A0A6J1Y1N9
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

32536:SLC25A40
gene id: 32536:SLC25A40
uniprot id: A0A6J0A977
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

32536:NECTIN3
gene id: 32536:NECTIN3
uniprot id: A0A6J2AZ59
names: Similarity
messages: Belongs to the nectin family.

32536:FEZ2
gene id: 32536:FEZ2
uniprot id: A0A6J1X6T3
uniprot id: A0A6J1XA79
names: Similarity
messages: Belongs to the zygin family.

32536:ERO1B
gene id: 32536:ERO1B
uniprot id: A0A6J1YCL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

32536:SLC49A3
gene id: 32536:SLC49A3
uniprot id: A0A6J1ZJ26
uniprot id: A0A6J1ZJI3
names: Subcellular Location Annotation
messages: Membrane

32536:ABCD2
gene id: 32536:ABCD2
uniprot id: A0A6J0A8D7
names: Subcellular Location Annotation
messages: Membrane

32536:CDCA5
gene id: 32536:CDCA5
uniprot id: A0A6J1Y7L5
uniprot id: A0A6J1Y7P4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

32536:LOC106982767
gene id: 32536:LOC106982767
uniprot id: A0A6J1Y433
names: Similarity
messages: Belongs to the UQCC4 family.

32536:LOC106986251
gene id: 32536:LOC106986251
uniprot id: A0A6J0A8E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NAGA
gene id: 32536:NAGA
uniprot id: A0A6J2AA75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

32536:MTMR10
gene id: 32536:MTMR10
uniprot id: A0A6J2A4S8
uniprot id: A0A6J2A5L4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

32536:FOXB1
gene id: 32536:FOXB1
uniprot id: A0A6J2A347
names: Subcellular Location Annotation
messages: Nucleus

32536:TRAPPC6B
gene id: 32536:TRAPPC6B
uniprot id: A0A6I9ZFD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: cis-Golgi network

32536:LOC106988082
gene id: 32536:LOC106988082
uniprot id: A0A6J0A9W4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:PFKP
gene id: 32536:PFKP
uniprot id: A0A6J2AH37
uniprot id: A0A6J2AKQ3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DSC2
gene id: 32536:DSC2
uniprot id: A0A6J2A3U5
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

32536:CLCN5
gene id: 32536:CLCN5
uniprot id: A0A6J1YXN4
uniprot id: A0A6J1YXR8
uniprot id: A0A6J1YYY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:PNPLA4
gene id: 32536:PNPLA4
uniprot id: A0A6J1YPD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:IRGC
gene id: 32536:IRGC
uniprot id: A0A6J1XM59
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

32536:COQ10A
gene id: 32536:COQ10A
uniprot id: A0A6J0A994
uniprot id: A0A6J2ABI6
uniprot id: A0A6J2ABS4
uniprot id: A0A6J2ACQ9
uniprot id: A0A6J2AFX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

32536:LOC106980741
gene id: 32536:LOC106980741
uniprot id: A0A6J2AQ77
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SLC30A6
gene id: 32536:SLC30A6
uniprot id: A0A6I9ZEG8
uniprot id: A0A6I9ZFY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

32536:ASAH1
gene id: 32536:ASAH1
uniprot id: A0A6J0AA94
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

32536:TEKT1
gene id: 32536:TEKT1
uniprot id: A0A6J1YDG1
uniprot id: A0A6J1YFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

32536:CAP1
gene id: 32536:CAP1
uniprot id: A0A6J0A7N8
uniprot id: A0A6J1ZE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Membrane

32536:PRICKLE3
gene id: 32536:PRICKLE3
uniprot id: A0A6J1YX05
uniprot id: A0A6J1YY83
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

32536:LOC106976322
gene id: 32536:LOC106976322
uniprot id: A0A6I9ZVN9
uniprot id: A0A6I9ZW64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ANKS3
gene id: 32536:ANKS3
uniprot id: A0A6I9ZYE1
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

32536:MRPS21
gene id: 32536:MRPS21
uniprot id: A0A6J0A579
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

32536:LGI2
gene id: 32536:LGI2
uniprot id: A0A6J1YG39
names: Subcellular Location Annotation
messages: Secreted

32536:SVIL
gene id: 32536:SVIL
uniprot id: A0A6I9ZSH0
uniprot id: A0A6J2AHS1
uniprot id: A0A6J2AHS6
uniprot id: A0A6J2AHT0
uniprot id: A0A6J2AIB3
uniprot id: A0A6J2AIB7
uniprot id: A0A6J2AJG4
uniprot id: A0A6J2AJH0
uniprot id: A0A6J2AJH4
uniprot id: A0A6J2ALW8
uniprot id: A0A6J2ALX4
uniprot id: A0A6J2AM99
uniprot id: A0A6J2AMA5
names: Similarity
messages: Belongs to the villin/gelsolin family.

32536:ARRDC2
gene id: 32536:ARRDC2
uniprot id: A0A6J1XNP8
uniprot id: A0A6J1XNQ3
uniprot id: A0A6J1XNY8
names: Similarity
messages: Belongs to the arrestin family.

32536:GGA1
gene id: 32536:GGA1
uniprot id: A0A6J2A9K7
uniprot id: A0A6J2AAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

32536:NR1H4
gene id: 32536:NR1H4
uniprot id: A0A6I9ZMF6
uniprot id: A0A6I9ZP30
uniprot id: A0A6I9ZS48
uniprot id: A0A6I9ZSY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:PPP2R5C
gene id: 32536:PPP2R5C
uniprot id: A0A6I9ZRZ0
uniprot id: A0A6I9ZVQ5
uniprot id: A0A6J1ZXX5
uniprot id: A0A6J1ZYC3
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

32536:LOC106988643
gene id: 32536:LOC106988643
uniprot id: A0A6J0AAK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:SYNJ1
gene id: 32536:SYNJ1
uniprot id: A0A6J1XY93
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

32536:CB2H6orf89
gene id: 32536:CB2H6orf89
uniprot id: A0A6I9ZPF4
uniprot id: A0A6I9ZQT7
uniprot id: A0A6J1ZA70
uniprot id: A0A6J1ZBJ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

32536:HSD17B2
gene id: 32536:HSD17B2
uniprot id: A0A6J0A629
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

32536:ANXA5
gene id: 32536:ANXA5
uniprot id: A0A6I9ZTS8
names: Domain
names: Function
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

32536:ZNF215
gene id: 32536:ZNF215
uniprot id: A0A6J2AGY2
names: Subcellular Location Annotation
messages: Nucleus

32536:NR1H3
gene id: 32536:NR1H3
uniprot id: A0A6I9ZV01
uniprot id: A0A6I9ZYE7
uniprot id: A0A6J2AFH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:SEPTIN6
gene id: 32536:SEPTIN6
uniprot id: A0A6J1YYC5
uniprot id: A0A6J1YZJ3
uniprot id: A0A6J1Z0C1
uniprot id: A0A6J1Z0C4
uniprot id: A0A6J1Z1L7
uniprot id: A0A6J1Z1M2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

32536:IL1B
gene id: 32536:IL1B
uniprot id: A0A6I9ZV73
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: IL1B production occurs in 2 steps, each being controlled by different stimuli. First, inflammatory signals, such as LPS, stimulate the synthesis and promote the accumulation of cytosolic stores of pro-IL1B (priming). Then additional signals are required for inflammasome assembly, leading to CASP1 activation, pro-IL1B processing and eventually secretion of the active cytokine. IL1B processing and secretion are temporarily associated.
messages: Lysosome
messages: Monomer. Interacts with MEFV.
messages: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted
messages: cytosol
messages: extracellular exosome

32536:TIMM21
gene id: 32536:TIMM21
uniprot id: A0A6I9ZZV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.

32536:BAIAP2
gene id: 32536:BAIAP2
uniprot id: A0A6J1YSC5
uniprot id: A0A6J1YTT4
uniprot id: A0A6J1YVK8
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

32536:UBE2D1
gene id: 32536:UBE2D1
uniprot id: A0A6I9ZR89
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

32536:FGF13
gene id: 32536:FGF13
uniprot id: A0A6J1Z0H7
uniprot id: A0A6J1Z1C1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:DNAJC22
gene id: 32536:DNAJC22
uniprot id: A0A6I9ZHW8
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane

32536:INHBA
gene id: 32536:INHBA
uniprot id: A0A6J2AD35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

32536:DPYSL2
gene id: 32536:DPYSL2
uniprot id: A0A6I9ZC97
uniprot id: A0A6I9ZDM6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

32536:BNIP3
gene id: 32536:BNIP3
uniprot id: A0A6J1ZNX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIP3 family.
messages: Membrane

32536:EIF4EBP2
gene id: 32536:EIF4EBP2
uniprot id: A0A6J1ZKH2
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

32536:EMC6
gene id: 32536:EMC6
uniprot id: A0A6J1XDI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:MINDY3
gene id: 32536:MINDY3
uniprot id: A0A6J2AH80
uniprot id: A0A6J2AIT4
uniprot id: A0A6J2ALN1
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

32536:PPDPFL
gene id: 32536:PPDPFL
uniprot id: A0A6J0A3A7
names: Similarity
messages: Belongs to the PPDPF family.

32536:HNF1B
gene id: 32536:HNF1B
uniprot id: A0A6J1XCC3
uniprot id: A0A6J1XCE2
uniprot id: A0A6J1XCF0
uniprot id: A0A6J1XCG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

32536:TEKT3
gene id: 32536:TEKT3
uniprot id: A0A6J0A0V3
uniprot id: A0A6J1YG35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

32536:SERPINA12
gene id: 32536:SERPINA12
uniprot id: A0A6I9ZXM6
uniprot id: A0A6J1ZY08
names: Similarity
messages: Belongs to the serpin family.

32536:FAM163A
gene id: 32536:FAM163A
uniprot id: A0A6J2AJG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

32536:TWSG1
gene id: 32536:TWSG1
uniprot id: A0A6J2A7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

32536:PRMT3
gene id: 32536:PRMT3
uniprot id: A0A6J2AJS2
names: Subcellular Location Annotation
messages: Cytoplasm

32536:MTFR1L
gene id: 32536:MTFR1L
uniprot id: A0A6J1ZFL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

32536:HERC6
gene id: 32536:HERC6
uniprot id: A0A6J1ZG60
uniprot id: A0A6J1ZGH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:FLVCR1
gene id: 32536:FLVCR1
uniprot id: A0A6J2APF7
names: Subcellular Location Annotation
messages: Membrane

32536:FAT3
gene id: 32536:FAT3
uniprot id: A0A6J1XTB2
uniprot id: A0A6J1XTD3
uniprot id: A0A6J1XTU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:GOSR1
gene id: 32536:GOSR1
uniprot id: A0A6I9ZK23
uniprot id: A0A6I9ZKA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

32536:FAM234A
gene id: 32536:FAM234A
uniprot id: A0A6I9ZXJ2
names: Similarity
messages: Belongs to the FAM234 family.

32536:PDLIM1
gene id: 32536:PDLIM1
uniprot id: A0A6J1ZLV0
names: Subcellular Location Annotation
messages: Z line

32536:SBNO1
gene id: 32536:SBNO1
uniprot id: A0A6J1Y518
uniprot id: A0A6J1Y592
uniprot id: A0A6J1Y5S9
uniprot id: A0A6J1Y5Z0
uniprot id: A0A6J1Y6Z8
names: Similarity
messages: Belongs to the SBNO family.

32536:ACKR4
gene id: 32536:ACKR4
uniprot id: A0A6J0A695
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:LOC106965718
gene id: 32536:LOC106965718
uniprot id: A0A6I9ZE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:B3GNT4
gene id: 32536:B3GNT4
uniprot id: A0A6I9ZIH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:PMM2
gene id: 32536:PMM2
uniprot id: A0A6I9ZPH3
uniprot id: A0A6J1Y2X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

32536:PROX2
gene id: 32536:PROX2
uniprot id: A0A6J2A0R1
names: Subcellular Location Annotation
messages: Nucleus

32536:CCL22
gene id: 32536:CCL22
uniprot id: A0A6I9ZS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

32536:PNRC1
gene id: 32536:PNRC1
uniprot id: A0A6J1Z748
names: Subcellular Location Annotation
messages: Nucleus

32536:YEATS4
gene id: 32536:YEATS4
uniprot id: A0A6I9ZI92
names: Subcellular Location Annotation
messages: Nucleus

32536:VAMP7
gene id: 32536:VAMP7
uniprot id: A0A6J0A628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

32536:LOC106972590
gene id: 32536:LOC106972590
uniprot id: A0A6I9ZQJ2
names: Similarity
messages: Belongs to the intermediate filament family.

32536:LARP7
gene id: 32536:LARP7
uniprot id: A0A6I9ZGI3
uniprot id: A0A6I9ZGM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

32536:NDRG3
gene id: 32536:NDRG3
uniprot id: A0A6J2A7J7
uniprot id: A0A6J2A7M2
uniprot id: A0A6J2A8G3
uniprot id: A0A6J2A8G8
uniprot id: A0A6J2ABU3
names: Similarity
messages: Belongs to the NDRG family.

32536:LOC106986228
gene id: 32536:LOC106986228
uniprot id: A0A6J0A7K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:RNF152
gene id: 32536:RNF152
uniprot id: A0A6J2A530
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNF152 family.
messages: Lysosome membrane
messages: Membrane

32536:GADD45A
gene id: 32536:GADD45A
uniprot id: A0A6J1ZEE1
names: Similarity
messages: Belongs to the GADD45 family.

32536:IGFBP6
gene id: 32536:IGFBP6
uniprot id: A0A6J1XHT8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:DZIP1
gene id: 32536:DZIP1
uniprot id: A0A6J1ZTM1
uniprot id: A0A6J1ZU20
uniprot id: A0A6J1ZUR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: cilium basal body

32536:RPAIN
gene id: 32536:RPAIN
uniprot id: A0A6J1YEP8
names: Subcellular Location Annotation
messages: Nucleus

32536:GGT7
gene id: 32536:GGT7
uniprot id: A0A6J2A787
uniprot id: A0A6J2A7A5
uniprot id: A0A6J2AB12
uniprot id: A0A6J2ABH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

32536:GIPC2
gene id: 32536:GIPC2
uniprot id: A0A6I9ZJP7
names: Similarity
messages: Belongs to the GIPC family.

32536:TM4SF5
gene id: 32536:TM4SF5
uniprot id: A0A6J1YF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

32536:F7
gene id: 32536:F7
uniprot id: A0A6J1ZUG3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:TFDP2
gene id: 32536:TFDP2
uniprot id: A0A6J0A011
uniprot id: A0A6J1ZJ12
uniprot id: A0A6J1ZKA5
uniprot id: A0A6J1ZLE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

32536:ORAI1
gene id: 32536:ORAI1
uniprot id: A0A6I9ZDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

32536:PSMC2
gene id: 32536:PSMC2
uniprot id: A0A6I9ZL66
names: Similarity
messages: Belongs to the AAA ATPase family.

32536:IRX2
gene id: 32536:IRX2
uniprot id: A0A6J1Z2Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

32536:RPL26
gene id: 32536:RPL26
uniprot id: A0A6I9ZP26
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

32536:FAM166A
gene id: 32536:FAM166A
uniprot id: A0A6J1YQR5
names: Similarity
messages: Belongs to the CIMIP2 family.

32536:CRPPA
gene id: 32536:CRPPA
uniprot id: A0A6J2ADA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

32536:SLC30A5
gene id: 32536:SLC30A5
uniprot id: A0A6J1XV11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

32536:LOC106988631
gene id: 32536:LOC106988631
uniprot id: A0A6J0A7Y1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:ACD
gene id: 32536:ACD
uniprot id: A0A6I9ZLE1
uniprot id: A0A6I9ZMZ3
uniprot id: A0A6I9ZPF1
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

32536:TMEM150A
gene id: 32536:TMEM150A
uniprot id: A0A6I9ZXI3
uniprot id: A0A6J2AH39
names: Subcellular Location Annotation
messages: Membrane

32536:NDUFAF2
gene id: 32536:NDUFAF2
uniprot id: A0A6I9ZW96
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

32536:GDI1
gene id: 32536:GDI1
uniprot id: A0A6J1YWH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

32536:PPP1R1A
gene id: 32536:PPP1R1A
uniprot id: A0A6J1XI49
uniprot id: A0A6J1XI92
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

32536:CHRM3
gene id: 32536:CHRM3
uniprot id: A0A6J1YCF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

32536:GFM1
gene id: 32536:GFM1
uniprot id: A0A6I9ZI16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

32536:PLPPR3
gene id: 32536:PLPPR3
uniprot id: A0A6J1YKF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

32536:KIF2A
gene id: 32536:KIF2A
uniprot id: A0A6J1XWP9
uniprot id: A0A6J1XWR1
uniprot id: A0A6J1XX31
uniprot id: A0A6J1XX38
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

32536:SRSF1
gene id: 32536:SRSF1
uniprot id: A0A6J0ACS9
names: Similarity
messages: Belongs to the splicing factor SR family.

32536:LOC113597472
gene id: 32536:LOC113597472
uniprot id: A0A6J1YWC5
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:PDE4A
gene id: 32536:PDE4A
uniprot id: A0A6J1YMM5
uniprot id: A0A6J1YMN0
uniprot id: A0A6J1YNZ9
uniprot id: A0A6J1YPA8
uniprot id: A0A6J1YQI8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:LOC106978165
gene id: 32536:LOC106978165
uniprot id: A0A6J1XAN7
uniprot id: A0A6J1XAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

32536:RPS19BP1
gene id: 32536:RPS19BP1
uniprot id: A0A6J2A9B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

32536:UGP2
gene id: 32536:UGP2
uniprot id: A0A6I9ZM59
uniprot id: A0A6I9ZNS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

32536:DDX3X
gene id: 32536:DDX3X
uniprot id: A0A6J1YYW7
uniprot id: A0A6J1YZQ9
uniprot id: A0A6J1Z0Z0
names: Similarity
messages: Belongs to the DEAD box helicase family.

32536:AUP1
gene id: 32536:AUP1
uniprot id: A0A6J0AAH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AUP1 family.
messages: Membrane

32536:ANKZF1
gene id: 32536:ANKZF1
uniprot id: A0A6J1YLB8
uniprot id: A0A6J1YP28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

32536:TOMM22
gene id: 32536:TOMM22
uniprot id: A0A6J0A250
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom22 family.
messages: Mitochondrion outer membrane

32536:APLN
gene id: 32536:APLN
uniprot id: A0A6J1YXY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apelin family.
messages: extracellular space

32536:EPS8L2
gene id: 32536:EPS8L2
uniprot id: A0A6J1YPR8
uniprot id: A0A6J1YRK4
names: Similarity
messages: Belongs to the EPS8 family.

32536:PIGK
gene id: 32536:PIGK
uniprot id: A0A6J1ZAS3
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.

32536:FYN
gene id: 32536:FYN
uniprot id: A0A6J1Z5W6
uniprot id: A0A6J1Z6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:MTRF1L
gene id: 32536:MTRF1L
uniprot id: A0A6I9ZR24
uniprot id: A0A6I9ZUI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

32536:CENPM
gene id: 32536:CENPM
uniprot id: A0A6J0A091
names: Subcellular Location Annotation
messages: Nucleus

32536:RPL18
gene id: 32536:RPL18
uniprot id: A0A6J0AAK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum

32536:PAH
gene id: 32536:PAH
uniprot id: A0A6J2AB99
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

32536:FOXO1
gene id: 32536:FOXO1
uniprot id: A0A6J1ZTR2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:RBPJ
gene id: 32536:RBPJ
uniprot id: A0A6I9ZPA8
uniprot id: A0A6I9ZPB3
uniprot id: A0A6I9ZST7
uniprot id: A0A6I9ZU36
uniprot id: A0A6J1YRK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

32536:ORC3
gene id: 32536:ORC3
uniprot id: A0A6J1Z752
uniprot id: A0A6J1Z8H6
uniprot id: A0A6J1Z8I2
uniprot id: A0A6J1Z9V5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

32536:GNB5
gene id: 32536:GNB5
uniprot id: A0A6J1ZZQ8
uniprot id: A0A6J2A2S7
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

32536:RBL2
gene id: 32536:RBL2
uniprot id: A0A6J1Y5U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

32536:AVPI1
gene id: 32536:AVPI1
uniprot id: A0A6I9ZCQ8
names: Function
messages: May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling.

32536:FNBP1L
gene id: 32536:FNBP1L
uniprot id: A0A6J1ZAW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

32536:IMPDH2
gene id: 32536:IMPDH2
uniprot id: A0A6I9ZWR4
uniprot id: A0A6I9ZZW1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

32536:LOC106988134
gene id: 32536:LOC106988134
uniprot id: A0A6J0A7C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

32536:CEP57
gene id: 32536:CEP57
uniprot id: A0A6I9ZIJ7
names: Similarity
messages: Belongs to the translokin family.

32536:LOC106966061
gene id: 32536:LOC106966061
uniprot id: A0A6I9ZBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106976015
gene id: 32536:LOC106976015
uniprot id: A0A6I9ZVS4
uniprot id: A0A6J1XAM2
names: Similarity
messages: Belongs to the Speedy/Ringo family.

32536:PLD5
gene id: 32536:PLD5
uniprot id: A0A6I9ZVA6
uniprot id: A0A6J1YB47
uniprot id: A0A6J1YBR2
uniprot id: A0A6J1YD17
names: Similarity
messages: Belongs to the phospholipase D family.

32536:STAG2
gene id: 32536:STAG2
uniprot id: A0A6J1YY56
uniprot id: A0A6J1YY71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

32536:AQP2
gene id: 32536:AQP2
uniprot id: A0A6J1XHB4
uniprot id: A0A6J1XHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

32536:TMEM167B
gene id: 32536:TMEM167B
uniprot id: A0A6I9ZXJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:MYADML2
gene id: 32536:MYADML2
uniprot id: A0A6J1YSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAL family.
messages: Membrane

32536:ASTL
gene id: 32536:ASTL
uniprot id: A0A6I9ZU53
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:DXO
gene id: 32536:DXO
uniprot id: A0A6J0A1M1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

32536:CLIC1
gene id: 32536:CLIC1
uniprot id: A0A6J0A605
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cell membrane
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: Nucleus membrane

32536:TMEM63B
gene id: 32536:TMEM63B
uniprot id: A0A6J1Z9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

32536:PLK1
gene id: 32536:PLK1
uniprot id: A0A6J1Y1W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

32536:DUSP16
gene id: 32536:DUSP16
uniprot id: A0A6J1XFX7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

32536:MOCS2
gene id: 32536:MOCS2
uniprot id: A0A6I9ZW51
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the small subunit (MOCS2A) from an overlapping reading frame.
messages: cytosol

32536:PLIN3
gene id: 32536:PLIN3
uniprot id: A0A6J1YJS0
names: Similarity
messages: Belongs to the perilipin family.

32536:TPH1
gene id: 32536:TPH1
uniprot id: A0A6J2AGA2
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

32536:PKLR
gene id: 32536:PKLR
uniprot id: A0A6J1YGE0
uniprot id: A0A6J1YIJ1
names: Similarity
messages: Belongs to the pyruvate kinase family.

32536:TYR
gene id: 32536:TYR
uniprot id: A0A6I9ZH81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

32536:A1CF
gene id: 32536:A1CF
uniprot id: A0A6J0A1G7
uniprot id: A0A6J1YM93
names: Subcellular Location Annotation
messages: Cytoplasm

32536:ABCC4
gene id: 32536:ABCC4
uniprot id: A0A6J1ZWA4
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106979016
gene id: 32536:LOC106979016
uniprot id: A0A6I9ZZL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PFKM
gene id: 32536:PFKM
uniprot id: A0A6I9ZJ88
uniprot id: A0A6J1XH21
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:MB
gene id: 32536:MB
uniprot id: A0A6J0A2H6
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

32536:CCNB1
gene id: 32536:CCNB1
uniprot id: A0A6I9ZWU4
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: Essential for the control of the cell cycle at the G2/M (mitosis) transition.

32536:E2F3
gene id: 32536:E2F3
uniprot id: A0A6J1XV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

32536:LOC106976557
gene id: 32536:LOC106976557
uniprot id: A0A6I9ZUY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PAPOLG
gene id: 32536:PAPOLG
uniprot id: A0A6I9ZNR8
uniprot id: A0A6J2AFH6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

32536:LOC106977808
gene id: 32536:LOC106977808
uniprot id: A0A6I9ZWS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PGM5
gene id: 32536:PGM5
uniprot id: A0A6J1XWD3
names: Similarity
messages: Belongs to the phosphohexose mutase family.

32536:DHTKD1
gene id: 32536:DHTKD1
uniprot id: A0A6J2AGY4
uniprot id: A0A6J2AII4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

32536:MED27
gene id: 32536:MED27
uniprot id: A0A6J0A6B5
uniprot id: A0A6J0A6N0
uniprot id: A0A6J0A7E3
uniprot id: A0A6J1XFJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 27 family.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

32536:HPS5
gene id: 32536:HPS5
uniprot id: A0A6J0A6H4
uniprot id: A0A6J2AG97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

32536:LOC106986865
gene id: 32536:LOC106986865
uniprot id: A0A6J0A5L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106970346
gene id: 32536:LOC106970346
uniprot id: A0A6I9ZHT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PBX1
gene id: 32536:PBX1
uniprot id: A0A6J2AN83
uniprot id: A0A6J2AQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

32536:HIRIP3
gene id: 32536:HIRIP3
uniprot id: A0A6I9ZEF5
names: Subcellular Location Annotation
messages: Nucleus

32536:FIGN
gene id: 32536:FIGN
uniprot id: A0A6J1Z1S7
uniprot id: A0A6J1Z587
names: Similarity
messages: Belongs to the AAA ATPase family.

32536:NT5C2
gene id: 32536:NT5C2
uniprot id: A0A6J1ZMP8
uniprot id: A0A6J1ZMZ4
uniprot id: A0A6J1ZNU3
uniprot id: A0A6J1ZRH0
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

32536:ST13
gene id: 32536:ST13
uniprot id: A0A6J0A083
names: Similarity
messages: Belongs to the FAM10 family.

32536:SLC6A5
gene id: 32536:SLC6A5
uniprot id: A0A6J2AH93
names: Subcellular Location Annotation
messages: Membrane

32536:KHDRBS1
gene id: 32536:KHDRBS1
uniprot id: A0A6J1ZE62
names: Similarity
messages: Belongs to the KHDRBS family.

32536:SUB1
gene id: 32536:SUB1
uniprot id: A0A6J2ANC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

32536:PCYT1B
gene id: 32536:PCYT1B
uniprot id: A0A6J1YZP2
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

32536:RAX
gene id: 32536:RAX
uniprot id: A0A6J2A4Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

32536:BCO2
gene id: 32536:BCO2
uniprot id: A0A6J1XIE5
uniprot id: A0A6J1XII7
uniprot id: A0A6J1XIN4
names: Cofactor
names: Similarity
messages: Belongs to the carotenoid oxygenase family.
messages: Binds 1 Fe(2+) ion per subunit.

32536:TSC22D3
gene id: 32536:TSC22D3
uniprot id: A0A6J1Z014
uniprot id: A0A6J1Z063
uniprot id: A0A6J1Z164
uniprot id: A0A6J1Z214
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

32536:FHIP2A
gene id: 32536:FHIP2A
uniprot id: A0A6J1ZS34
names: Similarity
messages: Belongs to the FHIP family.

32536:ADGRG2
gene id: 32536:ADGRG2
uniprot id: A0A6J1YZ13
uniprot id: A0A6J1Z2D0
names: Subcellular Location Annotation
messages: Membrane

32536:DNM3
gene id: 32536:DNM3
uniprot id: A0A6J1YB14
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

32536:ALDH3A1
gene id: 32536:ALDH3A1
uniprot id: A0A6J1YFX8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:CNOT7
gene id: 32536:CNOT7
uniprot id: A0A6J2ASR6
uniprot id: A0A6J2AX38
uniprot id: A0A6J2AXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

32536:TM9SF1
gene id: 32536:TM9SF1
uniprot id: A0A6J0A6V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

32536:IDI1
gene id: 32536:IDI1
uniprot id: A0A6J2AGM5
uniprot id: A0A6J2AKP9
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

32536:CTBS
gene id: 32536:CTBS
uniprot id: A0A6J1ZAI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Lysosome

32536:SPOPL
gene id: 32536:SPOPL
uniprot id: A0A6J1Z2T0
uniprot id: A0A6J1Z3S3
names: Similarity
messages: Belongs to the Tdpoz family.

32536:NKAPL
gene id: 32536:NKAPL
uniprot id: A0A6J0A5D2
names: Similarity
messages: Belongs to the NKAP family.

32536:HOATZ
gene id: 32536:HOATZ
uniprot id: A0A6J1XIG0
uniprot id: A0A6J1XIJ7
names: Similarity
messages: Belongs to the HOATZ family.

32536:PIGO
gene id: 32536:PIGO
uniprot id: A0A6J0A1W0
uniprot id: A0A6J0A2H2
uniprot id: A0A6J0A2S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:TAF13
gene id: 32536:TAF13
uniprot id: A0A6I9ZXT9
names: Subcellular Location Annotation
messages: Nucleus

32536:AARSD1
gene id: 32536:AARSD1
uniprot id: A0A6J1YJF3
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.

32536:DENND5B
gene id: 32536:DENND5B
uniprot id: A0A6J1XGN3
uniprot id: A0A6J1XGN6
uniprot id: A0A6J1XGP2
uniprot id: A0A6J1XGP4
uniprot id: A0A6J1XGS9
uniprot id: A0A6J1XGT2
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SERPINI2
gene id: 32536:SERPINI2
uniprot id: A0A6J0AD13
names: Similarity
messages: Belongs to the serpin family.

32536:MOK
gene id: 32536:MOK
uniprot id: A0A6J1ZYE1
uniprot id: A0A6J2A104
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:AFF4
gene id: 32536:AFF4
uniprot id: A0A6J2AT55
uniprot id: A0A6J2AVH2
uniprot id: A0A6J2AW55
names: Similarity
messages: Belongs to the AF4 family.

32536:ERN1
gene id: 32536:ERN1
uniprot id: A0A6J1YFN3
uniprot id: A0A6J1YGE7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:RARG
gene id: 32536:RARG
uniprot id: A0A6J1XHS2
uniprot id: A0A6J1XHW8
uniprot id: A0A6J1XI10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

32536:LOC106987182
gene id: 32536:LOC106987182
uniprot id: A0A6J0A613
names: Similarity
messages: Belongs to the SKP1 family.

32536:ACBD5
gene id: 32536:ACBD5
uniprot id: A0A6J2AJB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane
messages: Peroxisome membrane

32536:GRWD1
gene id: 32536:GRWD1
uniprot id: A0A6J1XMM8
names: Subcellular Location Annotation
messages: Nucleus

32536:SLC46A3
gene id: 32536:SLC46A3
uniprot id: A0A6J1ZWB4
names: Subcellular Location Annotation
messages: Membrane

32536:PAN3
gene id: 32536:PAN3
uniprot id: A0A6J1ZS92
uniprot id: A0A6J1ZSM3
uniprot id: A0A6J1ZTD2
uniprot id: A0A6J1ZUX3
uniprot id: A0A6J1ZWB0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

32536:SENP1
gene id: 32536:SENP1
uniprot id: A0A6I9ZKX7
names: Similarity
messages: Belongs to the peptidase C48 family.

32536:MTMR2
gene id: 32536:MTMR2
uniprot id: A0A6I9ZNQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

32536:CLIC5
gene id: 32536:CLIC5
uniprot id: A0A6J1Z9K2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

32536:TARS2
gene id: 32536:TARS2
uniprot id: A0A6J0A8Y2
uniprot id: A0A6J1Z3L6
uniprot id: A0A6J1Z3X2
uniprot id: A0A6J1Z4X4
uniprot id: A0A6J1Z5L7
uniprot id: A0A6J1Z5M1
uniprot id: A0A6J1Z6Z4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

32536:FGF14
gene id: 32536:FGF14
uniprot id: A0A6J1ZWJ3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:EDA
gene id: 32536:EDA
uniprot id: A0A6J1YWD0
uniprot id: A0A6J1YXM3
uniprot id: A0A6J1YY77
uniprot id: A0A6J1YZL9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

32536:LOC106988641
gene id: 32536:LOC106988641
uniprot id: A0A6J0AAL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:MDK
gene id: 32536:MDK
uniprot id: A0A6J2AJN1
names: Similarity
messages: Belongs to the pleiotrophin family.

32536:ERO1A
gene id: 32536:ERO1A
uniprot id: A0A6J1ZWK4
uniprot id: A0A6J1ZY43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

32536:WASF2
gene id: 32536:WASF2
uniprot id: A0A6J1ZFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

32536:LOC106986249
gene id: 32536:LOC106986249
uniprot id: A0A6J0A4R6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DCLRE1C
gene id: 32536:DCLRE1C
uniprot id: A0A6I9ZKG2
uniprot id: A0A6J2AL65
uniprot id: A0A6J2ALK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

32536:PIK3C2B
gene id: 32536:PIK3C2B
uniprot id: A0A6J2ALC6
uniprot id: A0A6J2ALD1
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

32536:FAM221B
gene id: 32536:FAM221B
uniprot id: A0A6I9ZYQ0
uniprot id: A0A6I9ZZD4
names: Similarity
messages: Belongs to the FAM221 family.

32536:HOXD8
gene id: 32536:HOXD8
uniprot id: A0A6J1Z1B4
names: Subcellular Location Annotation
messages: Nucleus

32536:NUPR1
gene id: 32536:NUPR1
uniprot id: A0A6I9ZES1
names: Similarity
messages: Belongs to the NUPR family.

32536:LEO1
gene id: 32536:LEO1
uniprot id: A0A6I9ZEW9
uniprot id: A0A6J2A024
names: Similarity
messages: Belongs to the LEO1 family.

32536:NSMCE4A
gene id: 32536:NSMCE4A
uniprot id: A0A6J1ZNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

32536:CAPZA3
gene id: 32536:CAPZA3
uniprot id: A0A6J1XG55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

32536:TMBIM6
gene id: 32536:TMBIM6
uniprot id: A0A6J1XHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

32536:ADAM33
gene id: 32536:ADAM33
uniprot id: A0A6J2A6I0
uniprot id: A0A6J2A7C3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:KCTD10
gene id: 32536:KCTD10
uniprot id: A0A6J1Y4J8
uniprot id: A0A6J1Y693
names: Similarity
messages: Belongs to the BACURD family.

32536:IRF6
gene id: 32536:IRF6
uniprot id: A0A6J2AP55
names: Subcellular Location Annotation
messages: Nucleus

32536:PKIA
gene id: 32536:PKIA
uniprot id: A0A6J0A693
uniprot id: A0A6J1ZRH9
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

32536:HOXD12
gene id: 32536:HOXD12
uniprot id: A0A6J1Z2J5
names: Subcellular Location Annotation
messages: Nucleus

32536:NDUFB4
gene id: 32536:NDUFB4
uniprot id: A0A6I9ZRD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB4 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

32536:LOC106986245
gene id: 32536:LOC106986245
uniprot id: A0A6J0A8E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106974577
gene id: 32536:LOC106974577
uniprot id: A0A6I9ZQ58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:PRDM14
gene id: 32536:PRDM14
uniprot id: A0A6I9ZF03
names: Subcellular Location Annotation
messages: Nucleus

32536:MPDZ
gene id: 32536:MPDZ
uniprot id: A0A6J1YD28
uniprot id: A0A6J1YD33
uniprot id: A0A6J1YD72
uniprot id: A0A6J1YD77
uniprot id: A0A6J1YDV0
uniprot id: A0A6J1YDV1
uniprot id: A0A6J1YEF7
uniprot id: A0A6J1YEG2
uniprot id: A0A6J1YF61
uniprot id: A0A6J1YF65
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

32536:OPA1
gene id: 32536:OPA1
uniprot id: A0A6J1ZHM4
uniprot id: A0A6J1ZIV7
uniprot id: A0A6J1ZL52
uniprot id: A0A6J1ZL55
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

32536:ACTL6B
gene id: 32536:ACTL6B
uniprot id: A0A6J1XZ51
names: Similarity
messages: Belongs to the actin family.

32536:SFRP1
gene id: 32536:SFRP1
uniprot id: A0A6J2AAV8
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ELOVL5
gene id: 32536:ELOVL5
uniprot id: A0A6J1ZAQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: dendrite

32536:IDE
gene id: 32536:IDE
uniprot id: A0A6I9ZFZ2
uniprot id: A0A6J1ZLR2
names: Similarity
messages: Belongs to the peptidase M16 family.

32536:ABCD1
gene id: 32536:ABCD1
uniprot id: A0A6J1YYN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

32536:ARSI
gene id: 32536:ARSI
uniprot id: A0A6J0A3T3
names: Similarity
messages: Belongs to the sulfatase family.

32536:LOC106969867
gene id: 32536:LOC106969867
uniprot id: A0A6I9ZJV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:CTNNBIP1
gene id: 32536:CTNNBIP1
uniprot id: A0A6J1ZFN3
names: Similarity
messages: Belongs to the CTNNBIP1 family.

32536:NUDT4
gene id: 32536:NUDT4
uniprot id: A0A6J2AAF9
uniprot id: A0A6J2AAQ8
names: Similarity
messages: Belongs to the Nudix hydrolase family. DIPP subfamily.

32536:PIF1
gene id: 32536:PIF1
uniprot id: A0A6J2A0H3
uniprot id: A0A6J2A0H8
uniprot id: A0A6J2A0S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

32536:SAMM50
gene id: 32536:SAMM50
uniprot id: A0A6J2ACR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

32536:PLIN2
gene id: 32536:PLIN2
uniprot id: A0A6J1YCU2
uniprot id: A0A6J1YEW8
names: Similarity
messages: Belongs to the perilipin family.

32536:PLET1
gene id: 32536:PLET1
uniprot id: A0A6J1XIF5
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

32536:AP1G1
gene id: 32536:AP1G1
uniprot id: A0A6J0AAW6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

32536:LAMTOR4
gene id: 32536:LAMTOR4
uniprot id: A0A6J0A966
uniprot id: A0A6J0AA40
names: Similarity
messages: Belongs to the LAMTOR4 family.

32536:HS3ST4
gene id: 32536:HS3ST4
uniprot id: A0A6J1YQK2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

32536:PPP6R2
gene id: 32536:PPP6R2
uniprot id: A0A6J2A8H9
uniprot id: A0A6J2A8K1
uniprot id: A0A6J2A9H6
uniprot id: A0A6J2ACC0
uniprot id: A0A6J2ACC4
uniprot id: A0A6J2ACS2
names: Similarity
messages: Belongs to the SAPS family.

32536:EFHC1
gene id: 32536:EFHC1
uniprot id: A0A6I9ZLI8
names: Subcellular Location Annotation
messages: cilium axoneme

32536:FAM187B
gene id: 32536:FAM187B
uniprot id: A0A6I9ZQC1
uniprot id: A0A6I9ZU70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

32536:LOC113596115
gene id: 32536:LOC113596115
uniprot id: A0A6J1YFZ1
names: Similarity
messages: Belongs to the peptidase C1 family.

32536:LOC106986851
gene id: 32536:LOC106986851
uniprot id: A0A6J0A5L4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

32536:JUNB
gene id: 32536:JUNB
uniprot id: A0A6J1YP82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

32536:LDLRAD3
gene id: 32536:LDLRAD3
uniprot id: A0A6I9ZRZ3
uniprot id: A0A6J2AFE2
uniprot id: A0A6J2AFU9
uniprot id: A0A6J2AJW6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:KCNA4
gene id: 32536:KCNA4
uniprot id: A0A6I9ZMB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: axon

32536:UBP1
gene id: 32536:UBP1
uniprot id: A0A6J1XUT9
uniprot id: A0A6J1XV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

32536:SMIM7
gene id: 32536:SMIM7
uniprot id: A0A6J0AB55
names: Similarity
messages: Belongs to the SMIM7 family.

32536:LSM8
gene id: 32536:LSM8
uniprot id: A0A6I9ZNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

32536:CB2H6orf120
gene id: 32536:CB2H6orf120
uniprot id: A0A6J1Z7F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
messages: Secreted

32536:SPOP
gene id: 32536:SPOP
uniprot id: A0A6J0A661
uniprot id: A0A6J1XBH8
uniprot id: A0A6J1XBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

32536:LOC106968051
gene id: 32536:LOC106968051
uniprot id: A0A6I9ZG70
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

32536:TLCD5
gene id: 32536:TLCD5
uniprot id: A0A6J1XJ76
uniprot id: A0A6J1XJF3
names: Subcellular Location Annotation
messages: Membrane

32536:NPY5R
gene id: 32536:NPY5R
uniprot id: A0A6J2A331
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

32536:RPS7
gene id: 32536:RPS7
uniprot id: A0A6J2AZI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: centrosome

32536:EDEM3
gene id: 32536:EDEM3
uniprot id: A0A6I9ZQK2
uniprot id: A0A6I9ZRY1
uniprot id: A0A6I9ZV48
uniprot id: A0A6I9ZV51
uniprot id: A0A6I9ZVP6
uniprot id: A0A6J2AJI3
uniprot id: A0A6J2AL56
uniprot id: A0A6J2ANN0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

32536:NAXD
gene id: 32536:NAXD
uniprot id: A0A6J1ZV37
uniprot id: A0A6J1ZWN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Mitochondrion

32536:RASGRP4
gene id: 32536:RASGRP4
uniprot id: A0A6J1Y7U1
uniprot id: A0A6J1Y829
uniprot id: A0A6J1Y8V7
names: Similarity
messages: Belongs to the RASGRP family.

32536:XPA
gene id: 32536:XPA
uniprot id: A0A6J1XS62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus

32536:CFAP144
gene id: 32536:CFAP144
uniprot id: A0A6I9ZJ28
names: Similarity
messages: Belongs to the CFAP144 family.

32536:LOC106966168
gene id: 32536:LOC106966168
uniprot id: A0A6J1YP03
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

32536:JUP
gene id: 32536:JUP
uniprot id: A0A6J1YHV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

32536:ADM
gene id: 32536:ADM
uniprot id: A0A6J2AHT5
uniprot id: A0A6J2AK94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

32536:NDUFA5
gene id: 32536:NDUFA5
uniprot id: A0A6I9ZMU1
uniprot id: A0A6I9ZNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

32536:CXADR
gene id: 32536:CXADR
uniprot id: A0A6J2AXW6
names: Subcellular Location Annotation
messages: Cell membrane

32536:RASGRP3
gene id: 32536:RASGRP3
uniprot id: A0A6I9ZJ38
names: Similarity
messages: Belongs to the RASGRP family.

32536:RPN1
gene id: 32536:RPN1
uniprot id: A0A6J1YKE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

32536:ABCC12
gene id: 32536:ABCC12
uniprot id: A0A6J0A6T1
uniprot id: A0A6J1Y5K7
uniprot id: A0A6J1Y5R3
names: Subcellular Location Annotation
messages: Membrane

32536:MMAA
gene id: 32536:MMAA
uniprot id: A0A6J0A1P7
uniprot id: A0A6J0A4S7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

32536:CNOT1
gene id: 32536:CNOT1
uniprot id: A0A6I9ZS54
uniprot id: A0A6I9ZTQ0
uniprot id: A0A6I9ZVS5
uniprot id: A0A6I9ZWT4
uniprot id: A0A6I9ZX69
uniprot id: A0A6I9ZX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

32536:BMX
gene id: 32536:BMX
uniprot id: A0A6J1YZZ2
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

32536:MED6
gene id: 32536:MED6
uniprot id: A0A6I9ZRV3
uniprot id: A0A6I9ZT47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

32536:MSRA
gene id: 32536:MSRA
uniprot id: A0A6J2A6F4
uniprot id: A0A6J2AA76
uniprot id: A0A6J2AAM2
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

32536:MAP3K12
gene id: 32536:MAP3K12
uniprot id: A0A6J1XI21
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: May be an activator of the JNK/SAPK pathway.

32536:TBX3
gene id: 32536:TBX3
uniprot id: A0A6J1Y458
uniprot id: A0A6J1Y4U6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:GJE1
gene id: 32536:GJE1
uniprot id: A0A6I9ZFV4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:LOC106986788
gene id: 32536:LOC106986788
uniprot id: A0A6J0A895
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SLC25A28
gene id: 32536:SLC25A28
uniprot id: A0A6I9ZHB7
uniprot id: A0A6J1ZMA4
uniprot id: A0A6J1ZMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:SCML1
gene id: 32536:SCML1
uniprot id: A0A6J1YYL4
uniprot id: A0A6J1YZS5
uniprot id: A0A6J1Z0K5
uniprot id: A0A6J1Z1V8
names: Similarity
messages: Belongs to the SCM family.

32536:TPM1
gene id: 32536:TPM1
uniprot id: A0A6J2A086
uniprot id: A0A6J2A0A2
uniprot id: A0A6J2A0A7
uniprot id: A0A6J2A0I2
uniprot id: A0A6J2A0I6
uniprot id: A0A6J2A0J1
uniprot id: A0A6J2A0J5
uniprot id: A0A6J2A0K0
uniprot id: A0A6J2A1A2
uniprot id: A0A6J2A1A8
uniprot id: A0A6J2A1B3
uniprot id: A0A6J2A387
uniprot id: A0A6J2A392
uniprot id: A0A6J2A397
uniprot id: A0A6J2A490
uniprot id: A0A6J2A495
uniprot id: A0A6J2A4A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

32536:TMEM33
gene id: 32536:TMEM33
uniprot id: A0A6J0A499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

32536:P2RY2
gene id: 32536:P2RY2
uniprot id: A0A6J1XSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:PNPLA6
gene id: 32536:PNPLA6
uniprot id: A0A6J1YLF4
uniprot id: A0A6J1YMK8
uniprot id: A0A6J1YML4
uniprot id: A0A6J1YN15
uniprot id: A0A6J1YP68
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:ZNF263
gene id: 32536:ZNF263
uniprot id: A0A6I9ZUW5
uniprot id: A0A6I9ZW38
uniprot id: A0A6J1Y3A3
names: Subcellular Location Annotation
messages: Nucleus

32536:SERINC1
gene id: 32536:SERINC1
uniprot id: A0A6I9ZNZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

32536:AEBP1
gene id: 32536:AEBP1
uniprot id: A0A6J1YC58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

32536:MOS
gene id: 32536:MOS
uniprot id: A0A6J0A385
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:NEDD9
gene id: 32536:NEDD9
uniprot id: A0A6I9ZK86
uniprot id: A0A6J1XU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

32536:SCN1B
gene id: 32536:SCN1B
uniprot id: A0A6J1Y6N4
names: Subcellular Location Annotation
messages: Membrane

32536:DUSP6
gene id: 32536:DUSP6
uniprot id: A0A6I9ZT36
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

32536:ADGRF4
gene id: 32536:ADGRF4
uniprot id: A0A6J1Z834
uniprot id: A0A6J1Z8P2
uniprot id: A0A6J1Z9H2
names: Subcellular Location Annotation
messages: Membrane

32536:STEAP3
gene id: 32536:STEAP3
uniprot id: A0A6J1Z2P9
uniprot id: A0A6J1Z4R4
uniprot id: A0A6J1Z647
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

32536:TRAF3
gene id: 32536:TRAF3
uniprot id: A0A6J1ZY17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

32536:CCDC85B
gene id: 32536:CCDC85B
uniprot id: A0A6J1YBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

32536:AIF1L
gene id: 32536:AIF1L
uniprot id: A0A6J0A3P8
uniprot id: A0A6J1XFF0
names: Subcellular Location Annotation
messages: ruffle membrane

32536:CRY2
gene id: 32536:CRY2
uniprot id: A0A6J2AJA5
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 FAD per subunit.

32536:SLC51A
gene id: 32536:SLC51A
uniprot id: A0A6J0A917
names: Subcellular Location Annotation
messages: Membrane

32536:QARS1
gene id: 32536:QARS1
uniprot id: A0A6I9ZVK9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:LOC106979003
gene id: 32536:LOC106979003
uniprot id: A0A6I9ZZK6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106986452
gene id: 32536:LOC106986452
uniprot id: A0A6J0A7I5
names: Similarity
messages: Belongs to the intermediate filament family.

32536:PSMB7
gene id: 32536:PSMB7
uniprot id: A0A6I9ZF32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

32536:SNW1
gene id: 32536:SNW1
uniprot id: A0A6I9ZTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

32536:HYI
gene id: 32536:HYI
uniprot id: A0A6J1ZDV6
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

32536:ZKSCAN2
gene id: 32536:ZKSCAN2
uniprot id: A0A6I9ZG97
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

32536:MFSD8
gene id: 32536:MFSD8
uniprot id: A0A6I9ZNF4
uniprot id: A0A6J1ZVR6
uniprot id: A0A6J1ZVS5
names: Subcellular Location Annotation
messages: Membrane

32536:YTHDC1
gene id: 32536:YTHDC1
uniprot id: A0A6J1Z800
uniprot id: A0A6J1Z820
uniprot id: A0A6J1Z8U9
uniprot id: A0A6J1Z9B7
uniprot id: A0A6J1Z9D2
uniprot id: A0A6J1Z9E0
uniprot id: A0A6J1ZBL9
names: Function
names: Similarity
messages: Belongs to the YTHDF family.
messages: Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing.

32536:SERBP1
gene id: 32536:SERBP1
uniprot id: A0A6J0A3J2
uniprot id: A0A6J0A667
uniprot id: A0A6J0A6I4
uniprot id: A0A6J0A795
names: Similarity
messages: Belongs to the SERBP1-HABP4 family.

32536:DAD1
gene id: 32536:DAD1
uniprot id: A0A6J0AA63
uniprot id: A0A6J1ZYJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

32536:LOC106976677
gene id: 32536:LOC106976677
uniprot id: A0A6J2AEP1
uniprot id: A0A6J2AG42
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

32536:CAND2
gene id: 32536:CAND2
uniprot id: A0A6J1Y0N3
uniprot id: A0A6J1Y102
names: Similarity
messages: Belongs to the CAND family.

32536:RBFOX1
gene id: 32536:RBFOX1
uniprot id: A0A6J1Y1F7
uniprot id: A0A6J1Y1G3
uniprot id: A0A6J1Y1G8
uniprot id: A0A6J1Y1H4
uniprot id: A0A6J1Y1H8
uniprot id: A0A6J1Y1R9
uniprot id: A0A6J1Y1S3
uniprot id: A0A6J1Y1S9
uniprot id: A0A6J1Y1T3
uniprot id: A0A6J1Y1T7
uniprot id: A0A6J1Y1X0
uniprot id: A0A6J1Y1X4
uniprot id: A0A6J1Y1X9
uniprot id: A0A6J1Y1Y5
uniprot id: A0A6J1Y282
uniprot id: A0A6J1Y290
uniprot id: A0A6J1Y377
uniprot id: A0A6J1Y382
uniprot id: A0A6J1Y388
uniprot id: A0A6J1Y3A4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

32536:SLC43A3
gene id: 32536:SLC43A3
uniprot id: A0A6J0A0I3
uniprot id: A0A6J1Y7Q8
names: Subcellular Location Annotation
messages: Membrane

32536:MAT1A
gene id: 32536:MAT1A
uniprot id: A0A6I9ZLD3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

32536:SYBU
gene id: 32536:SYBU
uniprot id: A0A6I9ZSI0
uniprot id: A0A6J1ZRP9
names: Subcellular Location Annotation
messages: Membrane

32536:ADAMDEC1
gene id: 32536:ADAMDEC1
uniprot id: A0A6J2AYK3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:FGF1
gene id: 32536:FGF1
uniprot id: A0A6I9ZHX5
uniprot id: A0A6J1Y0L8
uniprot id: A0A6J1Y134
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

32536:LANCL3
gene id: 32536:LANCL3
uniprot id: A0A6J1YZG2
names: Similarity
messages: Belongs to the LanC-like protein family.

32536:KCNK18
gene id: 32536:KCNK18
uniprot id: A0A6J1ZMD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

32536:LOC106986193
gene id: 32536:LOC106986193
uniprot id: A0A6J0A4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TACC1
gene id: 32536:TACC1
uniprot id: A0A6J2AB09
uniprot id: A0A6J2AB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

32536:NFYB
gene id: 32536:NFYB
uniprot id: A0A6I9ZN70
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
messages: Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding. Interacts with C1QBP.

32536:RTCB
gene id: 32536:RTCB
uniprot id: A0A6I9ZK30
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

32536:AP3B2
gene id: 32536:AP3B2
uniprot id: A0A6J2A2D5
uniprot id: A0A6J2A3J1
uniprot id: A0A6J2A6I1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

32536:TPST1
gene id: 32536:TPST1
uniprot id: A0A6J1XZI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

32536:TTC39A
gene id: 32536:TTC39A
uniprot id: A0A6I9ZSX4
uniprot id: A0A6J1ZBU9
uniprot id: A0A6J1ZBV4
uniprot id: A0A6J1ZCL4
uniprot id: A0A6J1ZD89
uniprot id: A0A6J1ZD94
uniprot id: A0A6J1ZE61
uniprot id: A0A6J1ZFB0
names: Similarity
messages: Belongs to the TTC39 family.

32536:CRABP1
gene id: 32536:CRABP1
uniprot id: A0A6J2A6Y6
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Belongs to the calycin superfamily. Lipocalin family.

32536:SYPL2
gene id: 32536:SYPL2
uniprot id: A0A6J1ZAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

32536:TTYH2
gene id: 32536:TTYH2
uniprot id: A0A6J1YH76
uniprot id: A0A6J1YHY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

32536:ADORA2B
gene id: 32536:ADORA2B
uniprot id: A0A6J1YFV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

32536:SMPDL3B
gene id: 32536:SMPDL3B
uniprot id: A0A6J1ZE51
uniprot id: A0A6J1ZF95
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

32536:YPEL5
gene id: 32536:YPEL5
uniprot id: A0A6J1XA60
names: Similarity
messages: Belongs to the yippee family.

32536:MTFP1
gene id: 32536:MTFP1
uniprot id: A0A6J1YPM0
uniprot id: A0A6J1YPZ7
names: Similarity
messages: Belongs to the MTFP1 family.

32536:TTC38
gene id: 32536:TTC38
uniprot id: A0A6J2ACJ4
names: Similarity
messages: Belongs to the TTC38 family.

32536:VPS33A
gene id: 32536:VPS33A
uniprot id: A0A6J1Y5W2
uniprot id: A0A6J1Y629
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

32536:CDK5RAP3
gene id: 32536:CDK5RAP3
uniprot id: A0A6J0A1U7
names: Similarity
messages: Belongs to the CDK5RAP3 family.

32536:CCDC90B
gene id: 32536:CCDC90B
uniprot id: A0A6I9ZTL9
uniprot id: A0A6J1XT15
names: Similarity
messages: Belongs to the CCDC90 family.

32536:NKTR
gene id: 32536:NKTR
uniprot id: A0A6J1XWA5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

32536:FBXO45
gene id: 32536:FBXO45
uniprot id: A0A6J1ZJU0
names: Similarity
messages: Belongs to the FBXO45/Fsn family.

32536:MTCH2
gene id: 32536:MTCH2
uniprot id: A0A6J2AEW5
uniprot id: A0A6J2AFA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:SNX4
gene id: 32536:SNX4
uniprot id: A0A6J1ZKR8
names: Similarity
messages: Belongs to the sorting nexin family.

32536:LOC106975148
gene id: 32536:LOC106975148
uniprot id: A0A6J1XJT3
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

32536:LOC106986472
gene id: 32536:LOC106986472
uniprot id: A0A6J0A8N1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ACTB
gene id: 32536:ACTB
uniprot id: A0A6J1Y0U5
names: Similarity
messages: Belongs to the actin family.

32536:CD79B
gene id: 32536:CD79B
uniprot id: A0A6I9ZYA4
uniprot id: A0A6I9ZZ82
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:DMRTA2
gene id: 32536:DMRTA2
uniprot id: A0A6J1ZBW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

32536:HOXA1
gene id: 32536:HOXA1
uniprot id: A0A6J2AQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus

32536:LOC106968229
gene id: 32536:LOC106968229
uniprot id: A0A6J1YAR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:EFNA4
gene id: 32536:EFNA4
uniprot id: A0A6J1YHT9
uniprot id: A0A6J1YIF1
uniprot id: A0A6J1YJ59
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:LOC106986478
gene id: 32536:LOC106986478
uniprot id: A0A6J2AI02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GATAD2A
gene id: 32536:GATAD2A
uniprot id: A0A6J1XP88
uniprot id: A0A6J1XPB5
names: Subcellular Location Annotation
messages: Nucleus

32536:NELL1
gene id: 32536:NELL1
uniprot id: A0A6J2AJR5
uniprot id: A0A6J2AK67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:TREX1
gene id: 32536:TREX1
uniprot id: A0A6J1XPK1
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.

32536:ALAS1
gene id: 32536:ALAS1
uniprot id: A0A6J0A5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

32536:TMEM230
gene id: 32536:TMEM230
uniprot id: A0A6I9ZX43
uniprot id: A0A6J0A0H1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

32536:HADHA
gene id: 32536:HADHA
uniprot id: A0A6J1X695
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

32536:ZUP1
gene id: 32536:ZUP1
uniprot id: A0A6I9ZGG1
uniprot id: A0A6J1Z948
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

32536:SLC25A51
gene id: 32536:SLC25A51
uniprot id: A0A6J1XRX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:BARHL2
gene id: 32536:BARHL2
uniprot id: A0A6I9ZES3
names: Subcellular Location Annotation
messages: Nucleus

32536:CHMP1B
gene id: 32536:CHMP1B
uniprot id: A0A6I9ZZK8
names: Similarity
messages: Belongs to the SNF7 family.

32536:ABLIM3
gene id: 32536:ABLIM3
uniprot id: A0A6J2ATG5
names: Subcellular Location Annotation
messages: Cytoplasm

32536:JPH2
gene id: 32536:JPH2
uniprot id: A0A6J2A7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

32536:GALNTL6
gene id: 32536:GALNTL6
uniprot id: A0A6J2A5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

32536:GLA
gene id: 32536:GLA
uniprot id: A0A6J0A2M4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

32536:RAB19
gene id: 32536:RAB19
uniprot id: A0A6J2AQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane

32536:EXOSC9
gene id: 32536:EXOSC9
uniprot id: A0A6I9ZS94
names: Subcellular Location Annotation
messages: Cytoplasm

32536:LOC106979693
gene id: 32536:LOC106979693
uniprot id: A0A6J0A0H7
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

32536:LOC106977081
gene id: 32536:LOC106977081
uniprot id: A0A6I9ZX95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMN family.
messages: Cajal body
messages: Perikaryon
messages: Z line
messages: gem
messages: neuron projection

32536:IKBKE
gene id: 32536:IKBKE
uniprot id: A0A6J2AL75
uniprot id: A0A6J2ALK8
uniprot id: A0A6J2AMT9
uniprot id: A0A6J2AQP9
names: Subcellular Location Annotation
messages: Cytoplasm

32536:MOCOS
gene id: 32536:MOCOS
uniprot id: A0A6J2A466
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

32536:LOC106979550
gene id: 32536:LOC106979550
uniprot id: A0A6I9ZX71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:NEUROD1
gene id: 32536:NEUROD1
uniprot id: A0A6J0ABW3
names: Subcellular Location Annotation
messages: Nucleus

32536:SERINC3
gene id: 32536:SERINC3
uniprot id: A0A6I9ZIV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

32536:XDH
gene id: 32536:XDH
uniprot id: A0A6I9ZEG3
uniprot id: A0A6I9ZFY3
uniprot id: A0A6J1X6M9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Homodimer. Interacts with BTN1A1.
messages: Peroxisome

32536:GCSH
gene id: 32536:GCSH
uniprot id: A0A6J0A4Z6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

32536:FAT2
gene id: 32536:FAT2
uniprot id: A0A6J2ATU1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:COL4A5
gene id: 32536:COL4A5
uniprot id: A0A6J1Z030
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

32536:TSPAN3
gene id: 32536:TSPAN3
uniprot id: A0A6J2A2G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:LOC106980102
gene id: 32536:LOC106980102
uniprot id: A0A6J1YWN9
names: Similarity
names: Subunit
messages: Belongs to the TRAPPC13 family.
messages: Part of the multisubunit TRAPP (transport protein particle) complex.

32536:WNT5A
gene id: 32536:WNT5A
uniprot id: A0A6J1XQS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

32536:BID
gene id: 32536:BID
uniprot id: A0A6J2AIP1
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:GAL3ST4
gene id: 32536:GAL3ST4
uniprot id: A0A6J0A902
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

32536:HACD2
gene id: 32536:HACD2
uniprot id: A0A6J1ZKK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:CPNE4
gene id: 32536:CPNE4
uniprot id: A0A6J1ZKN8
names: Similarity
messages: Belongs to the copine family.

32536:ARFGEF2
gene id: 32536:ARFGEF2
uniprot id: A0A6J0A2U1
uniprot id: A0A6J1YCQ1
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

32536:ZFYVE27
gene id: 32536:ZFYVE27
uniprot id: A0A6I9ZFN4
uniprot id: A0A6I9ZHE5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

32536:GOLT1B
gene id: 32536:GOLT1B
uniprot id: A0A6I9ZHI2
uniprot id: A0A6I9ZJ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

32536:DUOXA1
gene id: 32536:DUOXA1
uniprot id: A0A6J1ZZT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

32536:PRKG2
gene id: 32536:PRKG2
uniprot id: A0A6J1ZFD5
uniprot id: A0A6J1ZFE0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

32536:PTCD3
gene id: 32536:PTCD3
uniprot id: A0A6I9ZV62
uniprot id: A0A6I9ZYH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

32536:LOC106978682
gene id: 32536:LOC106978682
uniprot id: A0A6J1YGX9
names: Subcellular Location Annotation
messages: Membrane

32536:DIMT1
gene id: 32536:DIMT1
uniprot id: A0A6I9ZUP3
uniprot id: A0A6J1XWU5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PRR20G
gene id: 32536:PRR20G
uniprot id: A0A6J1YM54
names: Similarity
messages: Belongs to the PRR20 family.

32536:TOE1
gene id: 32536:TOE1
uniprot id: A0A6J1ZDK1
uniprot id: A0A6J1ZEI6
names: Similarity
messages: Belongs to the CAF1 family.

32536:TMEM115
gene id: 32536:TMEM115
uniprot id: A0A6J0A026
names: Subcellular Location Annotation
messages: Membrane

32536:DGKB
gene id: 32536:DGKB
uniprot id: A0A6J2ACX5
uniprot id: A0A6J2AD96
uniprot id: A0A6J2AEA6
uniprot id: A0A6J2AGV7
uniprot id: A0A6J2AGW3
uniprot id: A0A6J2AHB1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

32536:LOC106983863
gene id: 32536:LOC106983863
uniprot id: A0A6J0A263
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

32536:LOC106979312
gene id: 32536:LOC106979312
uniprot id: A0A6J2AS88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

32536:SAP30
gene id: 32536:SAP30
uniprot id: A0A6J2A509
uniprot id: A0A6J2A929
names: Similarity
messages: Belongs to the SAP30 family.

32536:PPT1
gene id: 32536:PPT1
uniprot id: A0A6J0AAB8
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

32536:PDE8A
gene id: 32536:PDE8A
uniprot id: A0A6J2A5Q8
uniprot id: A0A6J2A6G9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:BPNT2
gene id: 32536:BPNT2
uniprot id: A0A6J1Y1L6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

32536:GIPR
gene id: 32536:GIPR
uniprot id: A0A6J1XME8
uniprot id: A0A6J1XMG1
names: Subcellular Location Annotation
messages: Membrane

32536:DNTTIP1
gene id: 32536:DNTTIP1
uniprot id: A0A6J2A912
names: Subcellular Location Annotation
messages: Nucleus

32536:CERS4
gene id: 32536:CERS4
uniprot id: A0A6J1YMF6
uniprot id: A0A6J1YP27
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

32536:LOC106971966
gene id: 32536:LOC106971966
uniprot id: A0A6I9ZLN9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

32536:L3HYPDH
gene id: 32536:L3HYPDH
uniprot id: A0A6I9ZU11
names: Similarity
messages: Belongs to the proline racemase family.

32536:RNF145
gene id: 32536:RNF145
uniprot id: A0A6J1XA01
names: Subcellular Location Annotation
messages: Membrane

32536:SH3BGR
gene id: 32536:SH3BGR
uniprot id: A0A6I9ZHK9
uniprot id: A0A6J1XY05
names: Similarity
messages: Belongs to the SH3BGR family.

32536:RBM5
gene id: 32536:RBM5
uniprot id: A0A6J1XPW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus

32536:IRGQ
gene id: 32536:IRGQ
uniprot id: A0A6J1XM27
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

32536:AGK
gene id: 32536:AGK
uniprot id: A0A6J2ANK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

32536:SMARCD3
gene id: 32536:SMARCD3
uniprot id: A0A6J1YPN5
uniprot id: A0A6J1YR21
names: Similarity
messages: Belongs to the SMARCD family.

32536:SAXO2
gene id: 32536:SAXO2
uniprot id: A0A6J2A2I0
names: Similarity
messages: Belongs to the FAM154 family.

32536:PURG
gene id: 32536:PURG
uniprot id: A0A6J2AUX3
uniprot id: A0A6J2AXC5
uniprot id: A0A6J2AY33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

32536:SLCO6A1
gene id: 32536:SLCO6A1
uniprot id: A0A6J0A0A3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:NME7
gene id: 32536:NME7
uniprot id: A0A6I9ZDB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDK family.
messages: cilium axoneme

32536:CUEDC2
gene id: 32536:CUEDC2
uniprot id: A0A6I9ZE94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUEDC2 family.
messages: Cytoplasm
messages: Nucleus

32536:NAA10
gene id: 32536:NAA10
uniprot id: A0A6J1YV89
uniprot id: A0A6J1YYL9
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

32536:MCM5
gene id: 32536:MCM5
uniprot id: A0A6J2AE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

32536:CCR9
gene id: 32536:CCR9
uniprot id: A0A6I9ZKM9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:BRPF1
gene id: 32536:BRPF1
uniprot id: A0A6J1Y0D5
uniprot id: A0A6J1Y0E0
uniprot id: A0A6J1Y0N4
uniprot id: A0A6J1Y0N9
uniprot id: A0A6J1Y0R7
uniprot id: A0A6J1Y135
uniprot id: A0A6J1Y1K6
uniprot id: A0A6J1Y1L2
names: Subcellular Location Annotation
messages: Nucleus

32536:AGER
gene id: 32536:AGER
uniprot id: A0A6J0A1M6
uniprot id: A0A6J1Z9W6
names: Subcellular Location Annotation
messages: Cell membrane

32536:NOS2
gene id: 32536:NOS2
uniprot id: A0A6J1XCR5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

32536:MTMR11
gene id: 32536:MTMR11
uniprot id: A0A6J0A8Z3
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

32536:TFEC
gene id: 32536:TFEC
uniprot id: A0A6J2AMB8
uniprot id: A0A6J2AMP4
uniprot id: A0A6J2ARC7
uniprot id: A0A6J2ARV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

32536:GDF2
gene id: 32536:GDF2
uniprot id: A0A6J1ZNS7
names: Similarity
messages: Belongs to the TGF-beta family.

32536:PERP
gene id: 32536:PERP
uniprot id: A0A6J1Z6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

32536:ARPC4
gene id: 32536:ARPC4
uniprot id: A0A6J1Y0W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Cell projection
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: cytoskeleton

32536:LOC106966128
gene id: 32536:LOC106966128
uniprot id: A0A6I9ZD55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:C4BPA
gene id: 32536:C4BPA
uniprot id: A0A6J0A2G5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106988077
gene id: 32536:LOC106988077
uniprot id: A0A6J1XTQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

32536:BLK
gene id: 32536:BLK
uniprot id: A0A6J2A5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

32536:BCL7B
gene id: 32536:BCL7B
uniprot id: A0A6I9ZXP5
uniprot id: A0A6J1XYY8
names: Similarity
messages: Belongs to the BCL7 family.

32536:TSPAN31
gene id: 32536:TSPAN31
uniprot id: A0A6I9ZV27
uniprot id: A0A6J2AFN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:SNX31
gene id: 32536:SNX31
uniprot id: A0A6J0A121
uniprot id: A0A6J0A1A5
uniprot id: A0A6J1ZS05
uniprot id: A0A6J1ZTJ3
names: Similarity
messages: Belongs to the sorting nexin family.

32536:GABRR3
gene id: 32536:GABRR3
uniprot id: A0A6J2ATR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:VEZT
gene id: 32536:VEZT
uniprot id: A0A6I9ZNN6
uniprot id: A0A6J2AAA6
uniprot id: A0A6J2AAB1
uniprot id: A0A6J2AAK5
uniprot id: A0A6J2AAL0
uniprot id: A0A6J2AAL5
uniprot id: A0A6J2ABI7
uniprot id: A0A6J2AEA0
uniprot id: A0A6J2AEA5
uniprot id: A0A6J2AEP8
uniprot id: A0A6J2AEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

32536:BTG1
gene id: 32536:BTG1
uniprot id: A0A6J2ABP0
names: Similarity
messages: Belongs to the BTG family.

32536:TPD52
gene id: 32536:TPD52
uniprot id: A0A6J1ZVI3
names: Similarity
messages: Belongs to the TPD52 family.

32536:RACK1
gene id: 32536:RACK1
uniprot id: A0A6I9ZH92
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

32536:TPRG1
gene id: 32536:TPRG1
uniprot id: A0A6I9ZHM5
uniprot id: A0A6J1ZHP1
names: Similarity
messages: Belongs to the TPRG1 family.

32536:KCND2
gene id: 32536:KCND2
uniprot id: A0A6I9ZMV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.2/KCND2 sub-subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: dendrite
messages: dendritic spine

32536:MRM1
gene id: 32536:MRM1
uniprot id: A0A6I9ZXI1
uniprot id: A0A6J1XCB7
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

32536:SEC63
gene id: 32536:SEC63
uniprot id: A0A6J1Z6U0
names: Subcellular Location Annotation
messages: Membrane

32536:KCNE1
gene id: 32536:KCNE1
uniprot id: A0A6J1XY49
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the potassium channel KCNE family.
messages: Cell membrane
messages: Membrane

32536:EPHA5
gene id: 32536:EPHA5
uniprot id: A0A6J1Z7E8
uniprot id: A0A6J1Z7H9
uniprot id: A0A6J1Z887
uniprot id: A0A6J1Z8T2
uniprot id: A0A6J1Z8T7
uniprot id: A0A6J1ZAZ7
uniprot id: A0A6J1ZB02
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106972552
gene id: 32536:LOC106972552
uniprot id: A0A6J1YIH7
names: Similarity
messages: Belongs to the intermediate filament family.

32536:ACTL10
gene id: 32536:ACTL10
uniprot id: A0A6J2A743
names: Similarity
messages: Belongs to the actin family.

32536:TLR2
gene id: 32536:TLR2
uniprot id: A0A6J0A362
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

32536:CCZ1
gene id: 32536:CCZ1
uniprot id: A0A6J1Y0M7
names: Similarity
messages: Belongs to the CCZ1 family.

32536:IDH3A
gene id: 32536:IDH3A
uniprot id: A0A6J2A3X1
uniprot id: A0A6J2A6A8
uniprot id: A0A6J2A6Y2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

32536:CENPT
gene id: 32536:CENPT
uniprot id: A0A6I9ZJW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-T/CNN1 family.
messages: Nucleus
messages: kinetochore

32536:KCND3
gene id: 32536:KCND3
uniprot id: A0A6J1ZA90
uniprot id: A0A6J1ZBM9
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

32536:IRF2
gene id: 32536:IRF2
uniprot id: A0A6J2AXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

32536:SLC39A9
gene id: 32536:SLC39A9
uniprot id: A0A6I9ZMQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.
messages: perinuclear region
messages: trans-Golgi network membrane

32536:ANG
gene id: 32536:ANG
uniprot id: A0A6I9ZJB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

32536:SLC9A1
gene id: 32536:SLC9A1
uniprot id: A0A6I9ZXG3
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

32536:IL4
gene id: 32536:IL4
uniprot id: A0A6I9ZLE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-4/IL-13 family.
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
messages: Secreted

32536:CUTA
gene id: 32536:CUTA
uniprot id: A0A6J1Z8E9
uniprot id: A0A6J1Z988
uniprot id: A0A6J1Z9R0
names: Similarity
names: Subunit
messages: Belongs to the CutA family.
messages: Homotrimer.

32536:LOC106977861
gene id: 32536:LOC106977861
uniprot id: A0A6I9ZY48
uniprot id: A0A6J1YBE6
names: Similarity
messages: Belongs to the peptidase A1 family.

32536:RPS6KA3
gene id: 32536:RPS6KA3
uniprot id: A0A6J1Z103
uniprot id: A0A6J1Z2C0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

32536:RARRES1
gene id: 32536:RARRES1
uniprot id: A0A6J1ZNJ9
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

32536:KCNMA1
gene id: 32536:KCNMA1
uniprot id: A0A6J1ZL10
uniprot id: A0A6J1ZL21
uniprot id: A0A6J1ZLA3
uniprot id: A0A6J1ZLC1
uniprot id: A0A6J1ZLD1
uniprot id: A0A6J1ZM42
uniprot id: A0A6J1ZNB9
uniprot id: A0A6J1ZND5
uniprot id: A0A6J1ZNH4
uniprot id: A0A6J1ZPR9
uniprot id: A0A6J1ZPT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

32536:HSF4
gene id: 32536:HSF4
uniprot id: A0A6J2AR22
uniprot id: A0A6J2ATA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

32536:THEMIS
gene id: 32536:THEMIS
uniprot id: A0A6I9ZWV5
names: Similarity
messages: Belongs to the themis family.

32536:LOC106986791
gene id: 32536:LOC106986791
uniprot id: A0A6J0A5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:TIMM10B
gene id: 32536:TIMM10B
uniprot id: A0A6J1YVP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

32536:ISCU
gene id: 32536:ISCU
uniprot id: A0A6J1Y4A0
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Mitochondrial scaffold protein, of the core iron-sulfur cluster (ISC) assembly complex, that provides the structural architecture on which the [2Fe-2S] clusters are assembled. The core iron-sulfur cluster (ISC) assembly complex is involved in the de novo synthesis of a [2Fe-2S] cluster, the first step of the mitochondrial iron-sulfur protein biogenesis. This process is initiated by the cysteine desulfurase complex (NFS1:LYRM4:NDUFAB1) that produces persulfide which is delivered on the scaffold protein ISCU in a FXN-dependent manner. Then this complex is stabilized by FDX2 which provides reducing equivalents to accomplish the [2Fe-2S] cluster assembly. Finally, the [2Fe-2S] cluster is transferred from ISCU to chaperone proteins, including HSCB, HSPA9 and GLRX5. Exists as two slow interchanging conformational states, a structured (S) and disordered (D) form. May modulate NFS1 desulfurase activity in a zinc-dependent manner. Modulates the interaction between FXN and the cysteine desulfurase complex.

32536:MVD
gene id: 32536:MVD
uniprot id: A0A6J2AUL3
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

32536:FGFR1
gene id: 32536:FGFR1
uniprot id: A0A6J2AAD2
uniprot id: A0A6J2AAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Nucleus
messages: Vesicle
messages: cytosol

32536:DAZL
gene id: 32536:DAZL
uniprot id: A0A6I9ZJM7
names: Subcellular Location Annotation
messages: Cytoplasm

32536:SH3BP5L
gene id: 32536:SH3BP5L
uniprot id: A0A6I9ZQ30
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

32536:LOC106965730
gene id: 32536:LOC106965730
uniprot id: A0A6J1XFU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:SCML4
gene id: 32536:SCML4
uniprot id: A0A6J1Z633
uniprot id: A0A6J1Z854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

32536:EIF4EBP3
gene id: 32536:EIF4EBP3
uniprot id: A0A6I9ZIS6
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

32536:TMEM45B
gene id: 32536:TMEM45B
uniprot id: A0A6J1XJW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

32536:DMRTB1
gene id: 32536:DMRTB1
uniprot id: A0A6J1ZBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

32536:LOC106988038
gene id: 32536:LOC106988038
uniprot id: A0A6J1XTX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

32536:GSG1L2
gene id: 32536:GSG1L2
uniprot id: A0A6J1YDP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

32536:ACYP2
gene id: 32536:ACYP2
uniprot id: A0A6J2AE87
uniprot id: A0A6J2AFN0
uniprot id: A0A6J2AI84
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:ASF1A
gene id: 32536:ASF1A
uniprot id: A0A6I9ZEX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

32536:IL6
gene id: 32536:IL6
uniprot id: A0A6I9ZZW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

32536:FGF7
gene id: 32536:FGF7
uniprot id: A0A6I9ZDF5
uniprot id: A0A6I9ZEV7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:PBX2
gene id: 32536:PBX2
uniprot id: A0A6J1Z9X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

32536:CPSF4
gene id: 32536:CPSF4
uniprot id: A0A6I9ZYL8
uniprot id: A0A6J1XZL1
uniprot id: A0A6J1Y0H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

32536:LOC106965683
gene id: 32536:LOC106965683
uniprot id: A0A6J1ZQM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

32536:LOC106967103
gene id: 32536:LOC106967103
uniprot id: A0A6I9ZHV9
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

32536:LOC106969345
gene id: 32536:LOC106969345
uniprot id: A0A6I9ZKZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:HMCES
gene id: 32536:HMCES
uniprot id: A0A6J1YM11
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

32536:PCSK1
gene id: 32536:PCSK1
uniprot id: A0A6I9ZG61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

32536:PC
gene id: 32536:PC
uniprot id: A0A6J1Y928
uniprot id: A0A6J1YAY0
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

32536:MYH7B
gene id: 32536:MYH7B
uniprot id: A0A6J2A7B3
uniprot id: A0A6J2A845
uniprot id: A0A6J2AB17
uniprot id: A0A6J2ABI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: myofibril

32536:HOXD10
gene id: 32536:HOXD10
uniprot id: A0A6J0A9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

32536:NPY
gene id: 32536:NPY
uniprot id: A0A6J2ALT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

32536:UNC93A
gene id: 32536:UNC93A
uniprot id: A0A6J1Z4F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

32536:CD53
gene id: 32536:CD53
uniprot id: A0A6I9ZY29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:SENP7
gene id: 32536:SENP7
uniprot id: A0A6J2ATU3
uniprot id: A0A6J2AU86
uniprot id: A0A6J2AVW7
uniprot id: A0A6J2AYB7
uniprot id: A0A6J2AYC4
uniprot id: A0A6J2AZ09
uniprot id: A0A6J2AZ14
names: Similarity
messages: Belongs to the peptidase C48 family.

32536:LOC106980740
gene id: 32536:LOC106980740
uniprot id: A0A6J2ANK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106969870
gene id: 32536:LOC106969870
uniprot id: A0A6I9ZII5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DLX6
gene id: 32536:DLX6
uniprot id: A0A6J2AE46
names: Subcellular Location Annotation
messages: Nucleus

32536:PRPF38A
gene id: 32536:PRPF38A
uniprot id: A0A6J0A848
uniprot id: A0A6J0A8Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

32536:TBX20
gene id: 32536:TBX20
uniprot id: A0A6J2AR69
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

32536:LOC106988435
gene id: 32536:LOC106988435
uniprot id: A0A6J0A7Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:FAM241B
gene id: 32536:FAM241B
uniprot id: A0A6J1ZLK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

32536:RNF34
gene id: 32536:RNF34
uniprot id: A0A6J1Y4T1
names: Subcellular Location Annotation
messages: Cell membrane

32536:LONP1
gene id: 32536:LONP1
uniprot id: A0A6J1YK09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

32536:ZNF496
gene id: 32536:ZNF496
uniprot id: A0A6J1YMW9
uniprot id: A0A6J1YP86
uniprot id: A0A6J1YPK9
names: Subcellular Location Annotation
messages: Nucleus

32536:XKR5
gene id: 32536:XKR5
uniprot id: A0A6J1YM71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

32536:LOC106969855
gene id: 32536:LOC106969855
uniprot id: A0A6I9ZH18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:AP1S3
gene id: 32536:AP1S3
uniprot id: A0A6J1YKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

32536:KMT5C
gene id: 32536:KMT5C
uniprot id: A0A6J1XKS0
uniprot id: A0A6J1XKX3
names: Subcellular Location Annotation
messages: Nucleus

32536:SLC39A8
gene id: 32536:SLC39A8
uniprot id: A0A6J1ZIK7
names: Subcellular Location Annotation
messages: Membrane

32536:MAPK4
gene id: 32536:MAPK4
uniprot id: A0A6J2A8Q4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

32536:AP4S1
gene id: 32536:AP4S1
uniprot id: A0A6J1ZZ02
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

32536:MTFR1
gene id: 32536:MTFR1
uniprot id: A0A6J0A448
uniprot id: A0A6J0A6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

32536:CDH24
gene id: 32536:CDH24
uniprot id: A0A6J1ZUX1
uniprot id: A0A6J1ZYM9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

32536:LOC106969343
gene id: 32536:LOC106969343
uniprot id: A0A6I9ZGI1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:AATF
gene id: 32536:AATF
uniprot id: A0A6J0A1Q5
names: Similarity
messages: Belongs to the AATF family.

32536:IGF2BP1
gene id: 32536:IGF2BP1
uniprot id: A0A6J1XBE9
uniprot id: A0A6J1XBF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

32536:WDR48
gene id: 32536:WDR48
uniprot id: A0A6I9ZH38
uniprot id: A0A6J1XVB9
uniprot id: A0A6J1XVZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Late endosome

32536:AWAT1
gene id: 32536:AWAT1
uniprot id: A0A6J0A020
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:MPPED1
gene id: 32536:MPPED1
uniprot id: A0A6J2ACT3
names: Similarity
messages: Belongs to the UPF0046 family.

32536:PDE8B
gene id: 32536:PDE8B
uniprot id: A0A6I9ZSC0
uniprot id: A0A6J1XSA7
uniprot id: A0A6J1XSD2
uniprot id: A0A6J1XSE2
uniprot id: A0A6J1XSF6
uniprot id: A0A6J1XSJ8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

32536:IL25
gene id: 32536:IL25
uniprot id: A0A6J0A7P1
names: Similarity
messages: Belongs to the IL-17 family.

32536:IL17RE
gene id: 32536:IL17RE
uniprot id: A0A6J1Y0F5
uniprot id: A0A6J1Y0G0
uniprot id: A0A6J1Y0Q5
uniprot id: A0A6J1Y0Q8
names: Subcellular Location Annotation
messages: Membrane

32536:PIM1
gene id: 32536:PIM1
uniprot id: A0A6J1Z8T4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

32536:SNRPA1
gene id: 32536:SNRPA1
uniprot id: A0A6I9ZPW7
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

32536:GLE1
gene id: 32536:GLE1
uniprot id: A0A6I9ZBZ1
uniprot id: A0A6J1XF39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

32536:ATG4A
gene id: 32536:ATG4A
uniprot id: A0A6J1Z388
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

32536:MTCL1
gene id: 32536:MTCL1
uniprot id: A0A6J2A3B0
uniprot id: A0A6J2A3E5
uniprot id: A0A6J2A3F0
uniprot id: A0A6J2A4G0
uniprot id: A0A6J2A4G6
uniprot id: A0A6J2A6W2
uniprot id: A0A6J2A6W7
uniprot id: A0A6J2A6X3
uniprot id: A0A6J2A7G4
uniprot id: A0A6J2A7G9
uniprot id: A0A6J2A7H4
names: Similarity
messages: Belongs to the SOGA family.

32536:SCAND3
gene id: 32536:SCAND3
uniprot id: A0A6J1YR48
uniprot id: A0A6J1YR49
names: Subcellular Location Annotation
messages: Nucleus

32536:TMCO5A
gene id: 32536:TMCO5A
uniprot id: A0A6J0A462
uniprot id: A0A6J0A732
uniprot id: A0A6J2A1Q1
uniprot id: A0A6J2A2T4
names: Subcellular Location Annotation
messages: Membrane

32536:ARL4C
gene id: 32536:ARL4C
uniprot id: A0A6J1YD26
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

32536:NTRK3
gene id: 32536:NTRK3
uniprot id: A0A6J2A1X2
uniprot id: A0A6J2A260
uniprot id: A0A6J2A316
uniprot id: A0A6J2A566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Cell membrane
messages: Membrane

32536:LOC106977425
gene id: 32536:LOC106977425
uniprot id: A0A6I9ZU54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:MAP1LC3B
gene id: 32536:MAP1LC3B
uniprot id: A0A6J2AQN3
names: Similarity
messages: Belongs to the ATG8 family.

32536:TUBGCP2
gene id: 32536:TUBGCP2
uniprot id: A0A6J1ZP36
uniprot id: A0A6J1ZRN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

32536:DRC1
gene id: 32536:DRC1
uniprot id: A0A6J1XA21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC1 family.
messages: cilium axoneme
messages: flagellum axoneme

32536:ABCC2
gene id: 32536:ABCC2
uniprot id: A0A6I9ZE62
uniprot id: A0A6I9ZHC4
uniprot id: A0A6J1ZMK5
uniprot id: A0A6J1ZR01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

32536:SNX18
gene id: 32536:SNX18
uniprot id: A0A6J0A9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

32536:SKAP2
gene id: 32536:SKAP2
uniprot id: A0A6J2ALV0
names: Similarity
messages: Belongs to the SKAP family.

32536:PTDSS1
gene id: 32536:PTDSS1
uniprot id: A0A6J1ZRE6
uniprot id: A0A6J1ZV44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:LOC106968777
gene id: 32536:LOC106968777
uniprot id: A0A6I9ZIT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

32536:ATP5PF
gene id: 32536:ATP5PF
uniprot id: A0A6J0A4D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

32536:MRPL24
gene id: 32536:MRPL24
uniprot id: A0A6J0A866
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

32536:NDUFS5
gene id: 32536:NDUFS5
uniprot id: A0A6I9ZNF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

32536:LOC113598803
gene id: 32536:LOC113598803
uniprot id: A0A6J1Z842
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

32536:TCEANC2
gene id: 32536:TCEANC2
uniprot id: A0A6I9ZSQ8
uniprot id: A0A6J1ZBJ5
names: Subcellular Location Annotation
messages: Nucleus

32536:TTR
gene id: 32536:TTR
uniprot id: A0A6J0A4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

32536:DNAI7
gene id: 32536:DNAI7
uniprot id: A0A6I9ZKF0
uniprot id: A0A6J1XGE3
uniprot id: A0A6J1XGE6
names: Similarity
messages: Belongs to the DNAI7 family.

32536:KCNJ10
gene id: 32536:KCNJ10
uniprot id: A0A6J0A409
uniprot id: A0A6J1YID9
uniprot id: A0A6J1YJ07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

32536:AMY2B
gene id: 32536:AMY2B
uniprot id: A0A6I9ZED5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

32536:RAB38
gene id: 32536:RAB38
uniprot id: A0A6I9ZE82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

32536:SEC31B
gene id: 32536:SEC31B
uniprot id: A0A6J1ZML9
uniprot id: A0A6J1ZNG7
uniprot id: A0A6J1ZR23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

32536:PGF
gene id: 32536:PGF
uniprot id: A0A6I9ZNA0
uniprot id: A0A6I9ZPX7
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

32536:HOXA9
gene id: 32536:HOXA9
uniprot id: A0A6J0A9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

32536:JAGN1
gene id: 32536:JAGN1
uniprot id: A0A6I9ZM96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:C7
gene id: 32536:C7
uniprot id: A0A6I9ZIN7
uniprot id: A0A6I9ZLP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:KCNA10
gene id: 32536:KCNA10
uniprot id: A0A6I9ZTV6
names: Subcellular Location Annotation
messages: Membrane

32536:RPRD1B
gene id: 32536:RPRD1B
uniprot id: A0A6I9ZT60
uniprot id: A0A6I9ZTY4
names: Function
names: Similarity
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD.

32536:ANXA11
gene id: 32536:ANXA11
uniprot id: A0A6J1ZL46
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

32536:SMCO2
gene id: 32536:SMCO2
uniprot id: A0A6J1XGJ7
uniprot id: A0A6J1XGK4
names: Subcellular Location Annotation
messages: Membrane

32536:TNK1
gene id: 32536:TNK1
uniprot id: A0A6J1YEE3
names: Subcellular Location Annotation
messages: Cell membrane

32536:BOLA2B
gene id: 32536:BOLA2B
uniprot id: A0A6I9ZD77
names: Similarity
messages: Belongs to the BolA/IbaG family.

32536:MICAL3
gene id: 32536:MICAL3
uniprot id: A0A6J2AI23
uniprot id: A0A6J2AI29
uniprot id: A0A6J2AI33
uniprot id: A0A6J2AJU7
uniprot id: A0A6J2AMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

32536:MSL3
gene id: 32536:MSL3
uniprot id: A0A6J1YYI3
uniprot id: A0A6J1Z1T0
names: Subcellular Location Annotation
messages: Nucleus

32536:CA2H19orf25
gene id: 32536:CA2H19orf25
uniprot id: A0A6J1YLC0
names: Similarity
messages: Belongs to the UPF0449 family.

32536:SLC1A2
gene id: 32536:SLC1A2
uniprot id: A0A6J2AFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

32536:USP2
gene id: 32536:USP2
uniprot id: A0A6J1XJ20
uniprot id: A0A6J1XJ47
uniprot id: A0A6J1XJ99
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

32536:ALAD
gene id: 32536:ALAD
uniprot id: A0A6J1XDX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer; active form. Homohexamer; low activity form.

32536:TBPL1
gene id: 32536:TBPL1
uniprot id: A0A6J1Z577
uniprot id: A0A6J1Z5L6
names: Similarity
names: Subunit
messages: Belongs to the TBP family.
messages: Binds TFIIA and TFIIB.

32536:TP53I11
gene id: 32536:TP53I11
uniprot id: A0A6J2AJC1
names: Subcellular Location Annotation
messages: Membrane

32536:TMEM134
gene id: 32536:TMEM134
uniprot id: A0A6J1Y7B7
uniprot id: A0A6J1Y7E9
uniprot id: A0A6J1Y7F3
uniprot id: A0A6J1Y8F9
uniprot id: A0A6J1Y961
uniprot id: A0A6J1Y964
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

32536:KMT5A
gene id: 32536:KMT5A
uniprot id: A0A6J1Y3S2
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

32536:MRPL41
gene id: 32536:MRPL41
uniprot id: A0A6J0A8B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

32536:EEIG2
gene id: 32536:EEIG2
uniprot id: A0A6J1ZAZ4
names: Similarity
messages: Belongs to the EEIG family.

32536:RB1
gene id: 32536:RB1
uniprot id: A0A6J1ZVF2
uniprot id: A0A6J1ZWW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

32536:NCBP1
gene id: 32536:NCBP1
uniprot id: A0A6J1XRZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

32536:ESS2
gene id: 32536:ESS2
uniprot id: A0A6J0A1S9
uniprot id: A0A6J1YLR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

32536:LOC106976995
gene id: 32536:LOC106976995
uniprot id: A0A6J1ZA45
uniprot id: A0A6J1ZBG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

32536:NPRL3
gene id: 32536:NPRL3
uniprot id: A0A6J1Y3L9
uniprot id: A0A6J1Y3T1
uniprot id: A0A6J1Y5J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

32536:ACTL8
gene id: 32536:ACTL8
uniprot id: A0A6J1ZB53
names: Similarity
messages: Belongs to the actin family.

32536:HHIP
gene id: 32536:HHIP
uniprot id: A0A6J0A1S6
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:SDHAF4
gene id: 32536:SDHAF4
uniprot id: A0A6J0A0M5
names: Similarity
messages: Belongs to the SDHAF4 family.

32536:LPCAT3
gene id: 32536:LPCAT3
uniprot id: A0A6I9ZAL1
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106965999
gene id: 32536:LOC106965999
uniprot id: A0A6I9ZEG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

32536:SLC35C1
gene id: 32536:SLC35C1
uniprot id: A0A6I9ZXB6
uniprot id: A0A6J2AFN6
names: Subcellular Location Annotation
messages: Membrane

32536:TFB2M
gene id: 32536:TFB2M
uniprot id: A0A6I9ZJX8
uniprot id: A0A6J1YAP7
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:NUP210
gene id: 32536:NUP210
uniprot id: A0A6J1Y1A8
uniprot id: A0A6J1Y1L3
uniprot id: A0A6J1Y257
names: Similarity
messages: Belongs to the NUP210 family.

32536:SLC25A18
gene id: 32536:SLC25A18
uniprot id: A0A6I9ZAT2
uniprot id: A0A6I9ZFC0
uniprot id: A0A6I9ZFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

32536:KCNJ13
gene id: 32536:KCNJ13
uniprot id: A0A6I9ZQI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

32536:RNPEP
gene id: 32536:RNPEP
uniprot id: A0A6J2AQ23
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

32536:GABRB3
gene id: 32536:GABRB3
uniprot id: A0A6J2A2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:CD81
gene id: 32536:CD81
uniprot id: A0A6J1Y8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:NRP1
gene id: 32536:NRP1
uniprot id: A0A6J2AHV2
uniprot id: A0A6J2AID8
uniprot id: A0A6J2AJK2
uniprot id: A0A6J2AM12
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:PHLDA2
gene id: 32536:PHLDA2
uniprot id: A0A6J1Y978
names: Subcellular Location Annotation
messages: Cytoplasm

32536:KCMF1
gene id: 32536:KCMF1
uniprot id: A0A6J2AH58
names: Function
names: Similarity
messages: Belongs to the KCMF1 family.
messages: Has intrinsic E3 ubiquitin ligase activity and promotes ubiquitination.

32536:FAM110D
gene id: 32536:FAM110D
uniprot id: A0A6J1ZGK3
uniprot id: A0A6J1ZHN2
names: Similarity
messages: Belongs to the FAM110 family.

32536:FADS2
gene id: 32536:FADS2
uniprot id: A0A6J1Y9S1
uniprot id: A0A6J1Y9U7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

32536:NAP1L5
gene id: 32536:NAP1L5
uniprot id: A0A6J1ZGD3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

32536:DAXX
gene id: 32536:DAXX
uniprot id: A0A6J1Z994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAXX family.
messages: Cytoplasm
messages: PML body
messages: centromere
messages: nucleolus
messages: nucleoplasm

32536:LSM12
gene id: 32536:LSM12
uniprot id: A0A6J1YHW3
names: Similarity
messages: Belongs to the LSM12 family.

32536:ZDHHC2
gene id: 32536:ZDHHC2
uniprot id: A0A6I9ZMK8
uniprot id: A0A6J2AUN7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

32536:PFDN5
gene id: 32536:PFDN5
uniprot id: A0A6J0A3T6
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

32536:LOC106982579
gene id: 32536:LOC106982579
uniprot id: A0A6J1XWU0
uniprot id: A0A6J1XX77
uniprot id: A0A6J1XX78
uniprot id: A0A6J1XX80
uniprot id: A0A6J1XXT5
names: Domain
names: Function
names: Similarity
messages: Belongs to the BicD family.
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

32536:VAPA
gene id: 32536:VAPA
uniprot id: A0A6J2A377
uniprot id: A0A6J2A4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:TMEM132D
gene id: 32536:TMEM132D
uniprot id: A0A6J1Y6R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

32536:MRPL49
gene id: 32536:MRPL49
uniprot id: A0A6I9ZNK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

32536:NOSIP
gene id: 32536:NOSIP
uniprot id: A0A6J1XN26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOSIP family.
messages: Cytoplasm
messages: Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
messages: Nucleus

32536:CLPTM1L
gene id: 32536:CLPTM1L
uniprot id: A0A6J2AHM7
uniprot id: A0A6J2ALR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

32536:LOC113597574
gene id: 32536:LOC113597574
uniprot id: A0A6J1YXM7
names: Similarity
messages: Belongs to the Gfa family.

32536:PAQR6
gene id: 32536:PAQR6
uniprot id: A0A6J1YHI2
uniprot id: A0A6J1YID5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

32536:COPS9
gene id: 32536:COPS9
uniprot id: A0A6J1YA68
names: Similarity
messages: Belongs to the CSN9 family.

32536:CENPS
gene id: 32536:CENPS
uniprot id: A0A6J1ZFM4
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

32536:STAMBP
gene id: 32536:STAMBP
uniprot id: A0A6I9ZE63
uniprot id: A0A6I9ZH62
names: Similarity
messages: Belongs to the peptidase M67C family.

32536:SGTA
gene id: 32536:SGTA
uniprot id: A0A6J1YIQ7
names: Similarity
messages: Belongs to the SGT family.

32536:MFSD14B
gene id: 32536:MFSD14B
uniprot id: A0A6J1XX96
uniprot id: A0A6J1XXB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

32536:CHML
gene id: 32536:CHML
uniprot id: A0A6J1YBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

32536:RANBP6
gene id: 32536:RANBP6
uniprot id: A0A6J0A3N6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:HOXB6
gene id: 32536:HOXB6
uniprot id: A0A6J1XBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:CPNE6
gene id: 32536:CPNE6
uniprot id: A0A6J1ZVT2
names: Similarity
messages: Belongs to the copine family.

32536:NKIRAS1
gene id: 32536:NKIRAS1
uniprot id: A0A6I9ZY81
uniprot id: A0A6J1XWB4
uniprot id: A0A6J1XWE1
uniprot id: A0A6J1XWT1
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

32536:IGF2BP2
gene id: 32536:IGF2BP2
uniprot id: A0A6J1ZI50
uniprot id: A0A6J1ZLB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule

32536:DUSP13B
gene id: 32536:DUSP13B
uniprot id: A0A6I9ZGU4
uniprot id: A0A6J1ZPL9
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

32536:ARPIN
gene id: 32536:ARPIN
uniprot id: A0A6J2A670
names: Similarity
messages: Belongs to the Arpin family.

32536:KAT2A
gene id: 32536:KAT2A
uniprot id: A0A6J1YIF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

32536:DCBLD2
gene id: 32536:DCBLD2
uniprot id: A0A6J0A0L9
uniprot id: A0A6J2ATS0
uniprot id: A0A6J2AU57
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106989571
gene id: 32536:LOC106989571
uniprot id: A0A6J0A925
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:SDHD
gene id: 32536:SDHD
uniprot id: A0A6J0A2N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

32536:EPHA2
gene id: 32536:EPHA2
uniprot id: A0A6J1ZGD1
names: Subcellular Location Annotation
messages: Membrane

32536:USH1G
gene id: 32536:USH1G
uniprot id: A0A6J1YSE9
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

32536:LOC106966058
gene id: 32536:LOC106966058
uniprot id: A0A6I9ZG55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106966059
gene id: 32536:LOC106966059
uniprot id: A0A6I9ZG31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ATP6V0E1
gene id: 32536:ATP6V0E1
uniprot id: A0A6I9ZV22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

32536:LOC106986267
gene id: 32536:LOC106986267
uniprot id: A0A6J0A7N4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:VCP
gene id: 32536:VCP
uniprot id: A0A6I9ZYQ4
names: Similarity
messages: Belongs to the AAA ATPase family.

32536:PFDN1
gene id: 32536:PFDN1
uniprot id: A0A6I9ZIW5
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

32536:LOC106983424
gene id: 32536:LOC106983424
uniprot id: A0A6J0A1Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

32536:SKA2
gene id: 32536:SKA2
uniprot id: A0A6J0A9D1
uniprot id: A0A6J0ABR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA2 family.
messages: spindle

32536:DDX31
gene id: 32536:DDX31
uniprot id: A0A6J1XFN0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:SV2C
gene id: 32536:SV2C
uniprot id: A0A6J1XT45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

32536:MTX3
gene id: 32536:MTX3
uniprot id: A0A6I9ZQ10
uniprot id: A0A6I9ZQU5
uniprot id: A0A6J1XR93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

32536:PJVK
gene id: 32536:PJVK
uniprot id: A0A6J0AA68
names: Similarity
messages: Belongs to the gasdermin family.

32536:THBS2
gene id: 32536:THBS2
uniprot id: A0A6J1Z4B9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:GLIS1
gene id: 32536:GLIS1
uniprot id: A0A6J1ZDX0
uniprot id: A0A6J1ZF21
names: Similarity
messages: Belongs to the GLI C2H2-type zinc-finger protein family.

32536:LOC106969593
gene id: 32536:LOC106969593
uniprot id: A0A6I9ZI51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:CSNK1E
gene id: 32536:CSNK1E
uniprot id: A0A6J2A9G2
uniprot id: A0A6J2A9M8
uniprot id: A0A6J2AAL6
uniprot id: A0A6J2ADS3
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:GIMAP8
gene id: 32536:GIMAP8
uniprot id: A0A6J2AT58
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

32536:TSPAN4
gene id: 32536:TSPAN4
uniprot id: A0A6J1YRS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

32536:GLRA2
gene id: 32536:GLRA2
uniprot id: A0A6I9ZNH6
uniprot id: A0A6I9ZP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

32536:CA3H2orf68
gene id: 32536:CA3H2orf68
uniprot id: A0A6J2AH34
names: Similarity
messages: Belongs to the UPF0561 family.

32536:MALL
gene id: 32536:MALL
uniprot id: A0A6J1XAJ5
uniprot id: A0A6J1XAJ6
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106966137
gene id: 32536:LOC106966137
uniprot id: A0A6I9ZG82
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MEN1
gene id: 32536:MEN1
uniprot id: A0A6J1Y7X9
uniprot id: A0A6J1Y8N1
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106966071
gene id: 32536:LOC106966071
uniprot id: A0A6J1XSN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106980822
gene id: 32536:LOC106980822
uniprot id: A0A6J0A1A4
names: Subcellular Location Annotation
messages: Nucleus

32536:TMED1
gene id: 32536:TMED1
uniprot id: A0A6J1YLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

32536:NUDT18
gene id: 32536:NUDT18
uniprot id: A0A6J2AXR4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

32536:BMP6
gene id: 32536:BMP6
uniprot id: A0A6J1XU34
names: Similarity
messages: Belongs to the TGF-beta family.

32536:LYZL4
gene id: 32536:LYZL4
uniprot id: A0A6I9ZH40
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

32536:SOD2
gene id: 32536:SOD2
uniprot id: A0A6J1Z4M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

32536:DARS1
gene id: 32536:DARS1
uniprot id: A0A6I9ZJE5
uniprot id: A0A6J1Z2H2
uniprot id: A0A6J1Z5W8
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

32536:STX1A
gene id: 32536:STX1A
uniprot id: A0A6J1XYR8
uniprot id: A0A6J1XYV8
names: Similarity
messages: Belongs to the syntaxin family.

32536:FBLN5
gene id: 32536:FBLN5
uniprot id: A0A6J0A9Q8
uniprot id: A0A6J1ZXD5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106986181
gene id: 32536:LOC106986181
uniprot id: A0A6J0A758
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:WHAMM
gene id: 32536:WHAMM
uniprot id: A0A6J2A5T1
names: Subcellular Location Annotation
messages: Membrane

32536:MAK16
gene id: 32536:MAK16
uniprot id: A0A6I9ZF87
names: Similarity
messages: Belongs to the MAK16 family.

32536:UBA1
gene id: 32536:UBA1
uniprot id: A0A6J1YX62
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

32536:LOC113595211
gene id: 32536:LOC113595211
uniprot id: A0A6J1Y5C5
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

32536:FGF5
gene id: 32536:FGF5
uniprot id: A0A6J1ZCH1
uniprot id: A0A6J1ZF69
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:RPS13
gene id: 32536:RPS13
uniprot id: A0A6I9ZXP1
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

32536:NFKB2
gene id: 32536:NFKB2
uniprot id: A0A6J1ZMW2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

32536:EIF5A2
gene id: 32536:EIF5A2
uniprot id: A0A6J1ZIP4
uniprot id: A0A6J1ZLY5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

32536:CPT2
gene id: 32536:CPT2
uniprot id: A0A6J1ZCF2
uniprot id: A0A6J1ZDZ2
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

32536:ZSCAN25
gene id: 32536:ZSCAN25
uniprot id: A0A6J1XZJ0
names: Subcellular Location Annotation
messages: Nucleus

32536:RGMA
gene id: 32536:RGMA
uniprot id: A0A6J2A5V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

32536:LOC106965698
gene id: 32536:LOC106965698
uniprot id: A0A6I9ZE29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

32536:LOC106966674
gene id: 32536:LOC106966674
uniprot id: A0A6I9ZCI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ERLIN2
gene id: 32536:ERLIN2
uniprot id: A0A6I9ZYW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

32536:PPRC1
gene id: 32536:PPRC1
uniprot id: A0A6I9ZE89
names: Subcellular Location Annotation
messages: Nucleus

32536:COPS8
gene id: 32536:COPS8
uniprot id: A0A6J1YCJ7
uniprot id: A0A6J1YCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

32536:RPL21
gene id: 32536:RPL21
uniprot id: A0A6J0A6K5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

32536:GAL3ST1
gene id: 32536:GAL3ST1
uniprot id: A0A6J1YN77
uniprot id: A0A6J1YPL7
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

32536:CMC1
gene id: 32536:CMC1
uniprot id: A0A6J0A403
uniprot id: A0A6J1XVR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

32536:TMEM175
gene id: 32536:TMEM175
uniprot id: A0A6J1ZRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

32536:PPP1R16B
gene id: 32536:PPP1R16B
uniprot id: A0A6J2ABZ2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:PUS10
gene id: 32536:PUS10
uniprot id: A0A6J2AEF0
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

32536:REEP6
gene id: 32536:REEP6
uniprot id: A0A6J1YKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

32536:MAPK6
gene id: 32536:MAPK6
uniprot id: A0A6I9ZDG9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

32536:ERI1
gene id: 32536:ERI1
uniprot id: A0A6J0A5Z2
names: Subcellular Location Annotation
messages: Cytoplasm

32536:COMP
gene id: 32536:COMP
uniprot id: A0A6J1XNX5
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CLCN3
gene id: 32536:CLCN3
uniprot id: A0A6I9ZUW3
uniprot id: A0A6I9ZVX9
uniprot id: A0A6J2A475
uniprot id: A0A6J2A884
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

32536:YIPF5
gene id: 32536:YIPF5
uniprot id: A0A6I9ZUG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

32536:VDAC3
gene id: 32536:VDAC3
uniprot id: A0A6J2AFG2
names: Similarity
messages: Belongs to the eukaryotic mitochondrial porin family.

32536:CWF19L2
gene id: 32536:CWF19L2
uniprot id: A0A6J0A242
uniprot id: A0A6J1XI58
names: Similarity
messages: Belongs to the CWF19 family.

32536:NOB1
gene id: 32536:NOB1
uniprot id: A0A6I9ZQ29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

32536:LMOD2
gene id: 32536:LMOD2
uniprot id: A0A6J2AP96
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

32536:NKIRAS2
gene id: 32536:NKIRAS2
uniprot id: A0A6I9ZL08
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

32536:CIRBP
gene id: 32536:CIRBP
uniprot id: A0A6J1YJS4
uniprot id: A0A6J1YLB5
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with EIF4G1. Associates with ribosomes.
messages: nucleoplasm

32536:ASPA
gene id: 32536:ASPA
uniprot id: A0A6J0A6C1
uniprot id: A0A6J0A936
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

32536:HEPH
gene id: 32536:HEPH
uniprot id: A0A6J0A009
names: Similarity
messages: Belongs to the multicopper oxidase family.

32536:SLC35B1
gene id: 32536:SLC35B1
uniprot id: A0A6J1XBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

32536:DNASE1L3
gene id: 32536:DNASE1L3
uniprot id: A0A6J1Z416
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

32536:TGFBR1
gene id: 32536:TGFBR1
uniprot id: A0A6J1XS06
uniprot id: A0A6J1XSG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

32536:NEUROD6
gene id: 32536:NEUROD6
uniprot id: A0A6I9ZK16
uniprot id: A0A6J2AR35
names: Subcellular Location Annotation
messages: Nucleus

32536:RNASEH2B
gene id: 32536:RNASEH2B
uniprot id: A0A6J1ZSQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

32536:LDLRAD2
gene id: 32536:LDLRAD2
uniprot id: A0A6J1ZF58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:AMIGO1
gene id: 32536:AMIGO1
uniprot id: A0A6I9ZUI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: Membrane

32536:SRP14
gene id: 32536:SRP14
uniprot id: A0A6I9ZK50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

32536:SENP8
gene id: 32536:SENP8
uniprot id: A0A6I9ZTJ5
names: Similarity
messages: Belongs to the peptidase C48 family.

32536:PARD3B
gene id: 32536:PARD3B
uniprot id: A0A6I9ZW98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

32536:BCL9
gene id: 32536:BCL9
uniprot id: A0A6J1YQ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

32536:MYD88
gene id: 32536:MYD88
uniprot id: A0A6I9ZH70
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
messages: Cytoplasm
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains.

32536:SPDYC
gene id: 32536:SPDYC
uniprot id: A0A6J1Y9I2
names: Similarity
messages: Belongs to the Speedy/Ringo family.

32536:FBXO48
gene id: 32536:FBXO48
uniprot id: A0A6I9ZE25
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO9) composed of CUL1, SKP1, RBX1 and FBXO9. Interacts with TTI1 and TELO2; when TTI1 and TELO2 are phosphorylated by CK2.
messages: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability. Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1. Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway. Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation.

32536:FOXO4
gene id: 32536:FOXO4
uniprot id: A0A6J0A3J3
names: Subcellular Location Annotation
messages: Nucleus

32536:BZW1
gene id: 32536:BZW1
uniprot id: A0A6J1YWI7
uniprot id: A0A6J1YWL5
uniprot id: A0A6J1YZW4
names: Similarity
messages: Belongs to the BZW family.

32536:ZBTB8OS
gene id: 32536:ZBTB8OS
uniprot id: A0A6I9ZPZ8
uniprot id: A0A6I9ZRA9
uniprot id: A0A6J1ZDS0
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

32536:AP2S1
gene id: 32536:AP2S1
uniprot id: A0A6J1XMK2
uniprot id: A0A6J1XMM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

32536:ALDH7A1
gene id: 32536:ALDH7A1
uniprot id: A0A6I9ZLI4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

32536:SEMA6A
gene id: 32536:SEMA6A
uniprot id: A0A6J2ARL1
uniprot id: A0A6J2AS09
uniprot id: A0A6J2ATJ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:APOC4
gene id: 32536:APOC4
uniprot id: A0A6I9ZMB1
uniprot id: A0A6I9ZS01
uniprot id: A0A6J1XM04
uniprot id: A0A6J1XM05
uniprot id: P0DP53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C4 family.
messages: May participate in lipoprotein metabolism.
messages: Secreted

32536:GPRIN1
gene id: 32536:GPRIN1
uniprot id: A0A6J1XEU3
names: Function
messages: May be involved in neurite outgrowth.

32536:LOC106988845
gene id: 32536:LOC106988845
uniprot id: A0A6J0A8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

32536:TSC22D1
gene id: 32536:TSC22D1
uniprot id: A0A6J1ZU41
uniprot id: A0A6J1ZX26
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

32536:LOC106976620
gene id: 32536:LOC106976620
uniprot id: A0A6I9ZRJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:ERMN
gene id: 32536:ERMN
uniprot id: A0A6I9ZV52
names: Function
names: Subunit
messages: Binds actin.
messages: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS.

32536:KLHL15
gene id: 32536:KLHL15
uniprot id: A0A6J1YZ20
names: Subcellular Location Annotation
messages: Nucleus

32536:MRPL50
gene id: 32536:MRPL50
uniprot id: A0A6J1XSJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

32536:XK
gene id: 32536:XK
uniprot id: A0A6J1YXN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

32536:CPN1
gene id: 32536:CPN1
uniprot id: A0A6J1ZR06
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:GORAB
gene id: 32536:GORAB
uniprot id: A0A6I9ZET7
uniprot id: A0A6J1YB46
names: Similarity
messages: Belongs to the GORAB family.

32536:NOG
gene id: 32536:NOG
uniprot id: A0A6J1XBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

32536:POU2F1
gene id: 32536:POU2F1
uniprot id: A0A6J1YAS8
uniprot id: A0A6J1YAT5
uniprot id: A0A6J1YCQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

32536:ADNP
gene id: 32536:ADNP
uniprot id: A0A6J1YCD8
names: Subcellular Location Annotation
messages: Nucleus

32536:SLIT2
gene id: 32536:SLIT2
uniprot id: A0A6J0A832
uniprot id: A0A6J0A8C3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:DDX10
gene id: 32536:DDX10
uniprot id: A0A6J1XII0
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:LOC106986498
gene id: 32536:LOC106986498
uniprot id: A0A6J0A7K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GPR119
gene id: 32536:GPR119
uniprot id: A0A6J1YZX0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:SLC26A5
gene id: 32536:SLC26A5
uniprot id: A0A6J2AG39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Voltage-sensitive motor protein that drives outer hair cell (OHC) electromotility (eM) and participates in sound amplification in the hearing organ. Converts changes in the transmembrane electric potential into mechanical displacements resulting in the coupling of its expansion to movement of a charged voltage sensor across the lipid membrane. The nature of the voltage sensor is not completely clear, and two models compete. In the first model, acts as an incomplete transporter where intracellular chloride anion acts as extrinsic voltage sensor that drives conformational change in the protein which is sufficient to produce a length change in the plane of the membrane and hence in the length of the OHC. The second model in which multiple charged amino acid residues are distributed at the intracellular and extracellular membrane interfaces that form an intrinsic voltage sensor, whose movement produces the non-linear capacitance (NLC). However, the effective voltage sensor may be the result of a hybrid voltage sensor, assembled from intrinsic charge (charged residues) and extrinsic charge (bound anion). Notably, binding of anions to the anion-binding pocket partially neutralizes the intrinsic positive charge rather than to form an electrically negative sensor, therefore remaining charge may serve as voltage sensor that, after depolarization, moves from down (expanded state) to up (contracted) conformation, which is accompanied by an eccentric contraction of the intermembrane cross-sectional area of the protein as well as a major increase in the hydrophobic thickness of the protein having as consequences the plasma membrane thickening and the cell contraction after membrane depolarization. The anion-binding pocket transits from the inward-open (Down) state, where it is exposed toward the intracellular solvent in the absence of anion, to the occluded (Up) state upon anion binding. Salicylate competes for the anion-binding site and inhibits the voltage-sensor movement, and…

32536:IFT20
gene id: 32536:IFT20
uniprot id: A0A6J1XCS2
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

32536:DIAPH2
gene id: 32536:DIAPH2
uniprot id: A0A6J1YXY5
uniprot id: A0A6J1YZC5
names: Similarity
messages: Belongs to the formin homology family. Diaphanous subfamily.

32536:JAG2
gene id: 32536:JAG2
uniprot id: A0A6J1ZZH4
uniprot id: A0A6J2A1C5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

32536:NEK6
gene id: 32536:NEK6
uniprot id: A0A6J0ABX9
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:BCKDHA
gene id: 32536:BCKDHA
uniprot id: A0A6J1XLS8
uniprot id: A0A6J1XLV1
names: Function
names: Similarity
messages: Belongs to the BCKDHA family.
messages: Together with BCKDHB forms the heterotetrameric E1 subunit of the mitochondrial branched-chain alpha-ketoacid dehydrogenase (BCKD) complex. The BCKD complex catalyzes the multi-step oxidative decarboxylation of alpha-ketoacids derived from the branched-chain amino-acids valine, leucine and isoleucine producing CO2 and acyl-CoA which is subsequently utilized to produce energy. The E1 subunit catalyzes the first step with the decarboxylation of the alpha-ketoacid forming an enzyme-product intermediate. A reductive acylation mediated by the lipoylamide cofactor of E2 extracts the acyl group from the E1 active site for the next step of the reaction.

32536:NPBWR2
gene id: 32536:NPBWR2
uniprot id: A0A6I9ZP01
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

32536:CTNNB1
gene id: 32536:CTNNB1
uniprot id: A0A6J1XW55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

32536:C2
gene id: 32536:C2
uniprot id: A0A6J1Z8P0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

32536:MRPS24
gene id: 32536:MRPS24
uniprot id: A0A6I9ZEU8
uniprot id: A0A6J1YB59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

32536:CD99L2
gene id: 32536:CD99L2
uniprot id: A0A6J1YVJ6
uniprot id: A0A6J1YVN6
uniprot id: A0A6J1YWZ4
names: Similarity
messages: Belongs to the CD99 family.

32536:RIC8A
gene id: 32536:RIC8A
uniprot id: A0A6J1YR65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

32536:LOC106977528
gene id: 32536:LOC106977528
uniprot id: A0A6I9ZU96
uniprot id: A0A6J1XYM1
uniprot id: A0A6J1XYP4
uniprot id: A0A6J1XZM0
names: Subcellular Location Annotation
messages: Nucleus

32536:GNB1
gene id: 32536:GNB1
uniprot id: A0A6J1ZGL0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

32536:POU3F2
gene id: 32536:POU3F2
uniprot id: A0A6I9ZXN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

32536:RPL17
gene id: 32536:RPL17
uniprot id: A0A6I9ZTU3
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

32536:NR1D1
gene id: 32536:NR1D1
uniprot id: A0A6I9ZYF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

32536:SLC13A1
gene id: 32536:SLC13A1
uniprot id: A0A6J2AMW1
uniprot id: A0A6J2AP89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

32536:MAP2
gene id: 32536:MAP2
uniprot id: A0A6J1YRT9
names: Subcellular Location Annotation
messages: cytoskeleton

32536:DDX50
gene id: 32536:DDX50
uniprot id: A0A6I9ZHZ4
uniprot id: A0A6J1ZMS7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

32536:LOC106976537
gene id: 32536:LOC106976537
uniprot id: A0A6I9ZRF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:FAM118B
gene id: 32536:FAM118B
uniprot id: A0A6I9ZQL8
uniprot id: A0A6I9ZUF9
names: Similarity
messages: Belongs to the FAM118 family.

32536:CFDP1
gene id: 32536:CFDP1
uniprot id: A0A6J0A4U2
uniprot id: A0A6J0A5E6
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

32536:XIAP
gene id: 32536:XIAP
uniprot id: A0A6J1YZ12
names: Similarity
messages: Belongs to the IAP family.

32536:ODF2
gene id: 32536:ODF2
uniprot id: A0A6I9ZGF2
uniprot id: A0A6J1XF04
uniprot id: A0A6J1XF05
uniprot id: A0A6J1XF11
uniprot id: A0A6J1XF12
uniprot id: A0A6J1XF14
uniprot id: A0A6J1XF15
uniprot id: A0A6J1XF22
uniprot id: A0A6J1XF24
uniprot id: A0A6J1XF30
uniprot id: A0A6J1XF34
uniprot id: A0A6J1XF35
uniprot id: A0A6J1XF37
uniprot id: A0A6J1XF40
uniprot id: A0A6J1XF42
uniprot id: A0A6J1XF44
uniprot id: A0A6J1XF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

32536:TBC1D31
gene id: 32536:TBC1D31
uniprot id: A0A6I9ZYF8
uniprot id: A0A6J1ZQT1
names: Function
names: Subcellular Location Annotation
messages: Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
messages: centriolar satellite
messages: cilium basal body

32536:MAU2
gene id: 32536:MAU2
uniprot id: A0A6I9ZJ01
uniprot id: A0A6I9ZKN9
uniprot id: A0A6I9ZL05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

32536:RPL37
gene id: 32536:RPL37
uniprot id: A0A6I9ZNV6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

32536:LOC106971389
gene id: 32536:LOC106971389
uniprot id: A0A6I9ZMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:GRAMD1B
gene id: 32536:GRAMD1B
uniprot id: A0A6J1XJI3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

32536:RO60
gene id: 32536:RO60
uniprot id: A0A6J2AMX9
uniprot id: A0A6J2AQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

32536:NIPAL3
gene id: 32536:NIPAL3
uniprot id: A0A6I9ZWJ0
uniprot id: A0A6J1ZEJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

32536:NT5C3B
gene id: 32536:NT5C3B
uniprot id: A0A6J1YKD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

32536:MEF2D
gene id: 32536:MEF2D
uniprot id: A0A6J1YHD6
uniprot id: A0A6J1YI76
uniprot id: A0A6J1YIS6
uniprot id: A0A6J1YIT1
names: Subcellular Location Annotation
messages: Nucleus

32536:SLC12A4
gene id: 32536:SLC12A4
uniprot id: A0A6J2AR81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

32536:TRMT11
gene id: 32536:TRMT11
uniprot id: A0A6J0A4H2
uniprot id: A0A6J0A7E7
uniprot id: A0A6J0A873
names: Function
names: Subunit
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.
messages: Interacts with TRMT112.

32536:RAB4B
gene id: 32536:RAB4B
uniprot id: A0A6J1Y7N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

32536:SPACA3
gene id: 32536:SPACA3
uniprot id: A0A6J1XCJ9
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

32536:SHTN1
gene id: 32536:SHTN1
uniprot id: A0A6J1ZNB5
uniprot id: A0A6J1ZPG2
uniprot id: A0A6J1ZS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shootin family.
messages: Perikaryon
messages: axon
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

32536:CLNS1A
gene id: 32536:CLNS1A
uniprot id: A0A6J1XSI8
uniprot id: A0A6J1XSR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

32536:BCL2A1
gene id: 32536:BCL2A1
uniprot id: A0A6J0AAD6
names: Similarity
messages: Belongs to the Bcl-2 family.

32536:TEKT4
gene id: 32536:TEKT4
uniprot id: A0A6J1Y3A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

32536:LOC106970991
gene id: 32536:LOC106970991
uniprot id: A0A6J1ZKV7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.

32536:LEF1
gene id: 32536:LEF1
uniprot id: A0A6J0A4M0
uniprot id: A0A6J1ZJY5
uniprot id: A0A6J1ZJZ0
uniprot id: A0A6J1ZKB1
uniprot id: A0A6J1ZL53
uniprot id: A0A6J1ZMD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

32536:SLCO2A1
gene id: 32536:SLCO2A1
uniprot id: A0A6J1ZJC4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:MSR1
gene id: 32536:MSR1
uniprot id: A0A6J2AXV4
names: Subcellular Location Annotation
messages: Membrane

32536:CHST11
gene id: 32536:CHST11
uniprot id: A0A6J2AA99
uniprot id: A0A6J2ADY9
uniprot id: A0A6J2AEC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:CDR2
gene id: 32536:CDR2
uniprot id: A0A6I9ZML4
names: Similarity
messages: Belongs to the CDR2 family.

32536:PDPK1
gene id: 32536:PDPK1
uniprot id: A0A6I9ZZ96
uniprot id: A0A6J1Y3K2
uniprot id: A0A6J1Y4U7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

32536:SYNGR1
gene id: 32536:SYNGR1
uniprot id: A0A6J2A9C6
uniprot id: A0A6J2A9J0
uniprot id: A0A6J2ADN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

32536:ATXN10
gene id: 32536:ATXN10
uniprot id: A0A6J2A8R9
uniprot id: A0A6J2A9T3
uniprot id: A0A6J2ACL6
uniprot id: A0A6J2AD15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
messages: perinuclear region

32536:PCMTD2
gene id: 32536:PCMTD2
uniprot id: A0A6J1YDK9
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

32536:ARL6IP4
gene id: 32536:ARL6IP4
uniprot id: A0A6J1Y3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL6IP4 family.
messages: Nucleus speckle
messages: nucleolus

32536:GPR20
gene id: 32536:GPR20
uniprot id: A0A6J1ZTU6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:KCNC2
gene id: 32536:KCNC2
uniprot id: A0A6J2AAU6
uniprot id: A0A6J2AB39
uniprot id: A0A6J2AC06
uniprot id: A0A6J2AC15
uniprot id: A0A6J2AES0
uniprot id: A0A6J2AES5
uniprot id: A0A6J2AF83
names: Subcellular Location Annotation
messages: Membrane

32536:LOC106970349
gene id: 32536:LOC106970349
uniprot id: A0A6I9ZMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:POLR2B
gene id: 32536:POLR2B
uniprot id: A0A6I9ZMU8
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

32536:EIF3D
gene id: 32536:EIF3D
uniprot id: A0A6J0A1J8
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit D family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Cytoplasm
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.
messages: The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

32536:CSTF2
gene id: 32536:CSTF2
uniprot id: A0A6J1YY67
names: Subcellular Location Annotation
messages: Nucleus

32536:HSP90AB1
gene id: 32536:HSP90AB1
uniprot id: A0A6I9ZPH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

32536:B3GNT5
gene id: 32536:B3GNT5
uniprot id: A0A6J1ZJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

32536:PEBP4
gene id: 32536:PEBP4
uniprot id: A0A6J2AT64
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

32536:LOC113596844
gene id: 32536:LOC113596844
uniprot id: A0A6J1YQY9
uniprot id: A0A6J1YSD8
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

32536:RARS1
gene id: 32536:RARS1
uniprot id: A0A6I9ZKU9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:WASL
gene id: 32536:WASL
uniprot id: A0A6J2ARK7
names: Subcellular Location Annotation
messages: Nucleus

32536:SLC26A4
gene id: 32536:SLC26A4
uniprot id: A0A6J2ADA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

32536:ENO2
gene id: 32536:ENO2
uniprot id: A0A6J2AJJ8
uniprot id: A0A6J2ANM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

32536:LOC106982250
gene id: 32536:LOC106982250
uniprot id: A0A6J0A082
names: Similarity
messages: Belongs to the cytochrome b5 family.

32536:SNCB
gene id: 32536:SNCB
uniprot id: A0A6J1XF00
names: Similarity
messages: Belongs to the synuclein family.

32536:LOC106978319
gene id: 32536:LOC106978319
uniprot id: A0A6J1ZUX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

32536:DDX52
gene id: 32536:DDX52
uniprot id: A0A6I9ZYD3
uniprot id: A0A6J0A1G3
names: Domain
names: Function
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: RNA helicase.
messages: The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

32536:EXOC4
gene id: 32536:EXOC4
uniprot id: A0A6I9ZRK9
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

32536:CHD2
gene id: 32536:CHD2
uniprot id: A0A6J2A1S9
uniprot id: A0A6J2A224
uniprot id: A0A6J2A2Y8
names: Subcellular Location Annotation
messages: Nucleus

32536:ENKD1
gene id: 32536:ENKD1
uniprot id: A0A6J2ATW0
names: Subcellular Location Annotation
messages: cilium axoneme

32536:SNX30
gene id: 32536:SNX30
uniprot id: A0A6J1XDS7
uniprot id: A0A6J1XDV5
names: Similarity
messages: Belongs to the sorting nexin family.

32536:HDAC2
gene id: 32536:HDAC2
uniprot id: A0A6J1Z5V4
uniprot id: A0A6J1Z6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

32536:PDE6H
gene id: 32536:PDE6H
uniprot id: A0A6I9ZFN3
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

32536:PFDN2
gene id: 32536:PFDN2
uniprot id: A0A6I9ZY17
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

32536:RETNLB
gene id: 32536:RETNLB
uniprot id: A0A6I9ZQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

32536:CADM3
gene id: 32536:CADM3
uniprot id: A0A6J1YGR4
uniprot id: A0A6J1YGT7
names: Similarity
messages: Belongs to the nectin family.

32536:NUBPL
gene id: 32536:NUBPL
uniprot id: A0A6I9ZVM7
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

32536:UTP11
gene id: 32536:UTP11
uniprot id: A0A6I9ZLS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

32536:MMP7
gene id: 32536:MMP7
uniprot id: A0A6I9ZWE0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Can bind about 5 Ca(2+) ions per subunit.

32536:ATP5PO
gene id: 32536:ATP5PO
uniprot id: A0A6I9ZF52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

32536:SLC26A11
gene id: 32536:SLC26A11
uniprot id: A0A6J1YUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

32536:STAB1
gene id: 32536:STAB1
uniprot id: A0A6J1XQ96
uniprot id: A0A6J1XQ99
uniprot id: A0A6J1XQG1
uniprot id: A0A6J1XQG8
uniprot id: A0A6J1XQG9
uniprot id: A0A6J1XQK6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:KRR1
gene id: 32536:KRR1
uniprot id: A0A6I9ZDL5
uniprot id: A0A6J2AEQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

32536:ODF1
gene id: 32536:ODF1
uniprot id: A0A6J0A180
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

32536:PSMD11
gene id: 32536:PSMD11
uniprot id: A0A6J1XCJ2
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

32536:CCNH
gene id: 32536:CCNH
uniprot id: A0A6I9ZZ24
uniprot id: A0A6J1XQ07
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

32536:LOC106973491
gene id: 32536:LOC106973491
uniprot id: A0A6I9ZRS9
names: Similarity
messages: Belongs to the cytochrome P450 family.

32536:LOC106966000
gene id: 32536:LOC106966000
uniprot id: A0A6I9ZG25
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

32536:ABCB7
gene id: 32536:ABCB7
uniprot id: A0A6J1YWK7
names: Subcellular Location Annotation
messages: Membrane

32536:RAD54L2
gene id: 32536:RAD54L2
uniprot id: A0A6J1XQB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

32536:INTU
gene id: 32536:INTU
uniprot id: A0A6J0A7L2
uniprot id: A0A6J1ZVU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

32536:HIBCH
gene id: 32536:HIBCH
uniprot id: A0A6J1Z0Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

32536:SERP1
gene id: 32536:SERP1
uniprot id: A0A6I9ZPF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAMP4 family.
messages: Endoplasmic reticulum membrane
messages: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation.
messages: Membrane

32536:TMC5
gene id: 32536:TMC5
uniprot id: A0A6I9ZNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

32536:CLPP
gene id: 32536:CLPP
uniprot id: A0A6J1YKV8
names: Similarity
messages: Belongs to the peptidase S14 family.

32536:STUM
gene id: 32536:STUM
uniprot id: A0A6J1YBG0
names: Subcellular Location Annotation
messages: Membrane

32536:SNX8
gene id: 32536:SNX8
uniprot id: A0A6J1Y042
uniprot id: A0A6J1Y0H9
uniprot id: A0A6J1Y114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

32536:SLC7A8
gene id: 32536:SLC7A8
uniprot id: A0A6J0A7P8
uniprot id: A0A6J1ZX92
uniprot id: A0A6J1ZYN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Cell membrane
messages: Membrane

32536:RFC4
gene id: 32536:RFC4
uniprot id: A0A6I9ZJE8
uniprot id: A0A6J1ZI30
uniprot id: A0A6J1ZK46
names: Similarity
messages: Belongs to the activator 1 small subunits family.

32536:GABRP
gene id: 32536:GABRP
uniprot id: A0A6I9ZSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

32536:POU2F3
gene id: 32536:POU2F3
uniprot id: A0A6J1XJB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus

32536:VARS2
gene id: 32536:VARS2
uniprot id: A0A6I9ZCE2
uniprot id: A0A6I9ZGX4
uniprot id: A0A6J1YX85
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

32536:MAT2B
gene id: 32536:MAT2B
uniprot id: A0A6I9ZMH5
uniprot id: A0A6J1XAU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

32536:VBP1
gene id: 32536:VBP1
uniprot id: A0A6J1YWB1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

32536:SMYD2
gene id: 32536:SMYD2
uniprot id: A0A6J2APD4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
messages: cytosol

32536:NUP62CL
gene id: 32536:NUP62CL
uniprot id: A0A6J1Z1S9
uniprot id: A0A6J1Z349
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

32536:RPL14
gene id: 32536:RPL14
uniprot id: A0A6I9ZCH0
uniprot id: A0A6I9ZFE8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

32536:DNM1
gene id: 32536:DNM1
uniprot id: A0A6J1XEY7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

32536:CATSPERD
gene id: 32536:CATSPERD
uniprot id: A0A6J1YLF7
names: Similarity
messages: Belongs to the CATSPERD family.

32536:GDF1
gene id: 32536:GDF1
uniprot id: A0A6J1XNY6
names: Similarity
messages: Belongs to the TGF-beta family.

32536:CMKLR2
gene id: 32536:CMKLR2
uniprot id: A0A6I9ZRN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

32536:CFL1
gene id: 32536:CFL1
uniprot id: A0A6J1Y9Y5
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

32536:SCGB1A1
gene id: 32536:SCGB1A1
uniprot id: A0A6J0A982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

32536:LOC106986182
gene id: 32536:LOC106986182
uniprot id: A0A6J0A897
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:DPYS
gene id: 32536:DPYS
uniprot id: A0A6J1ZR03
uniprot id: A0A6J1ZUP6
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

32536:SUMO3
gene id: 32536:SUMO3
uniprot id: A0A6J1XXQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

32536:NAP1L2
gene id: 32536:NAP1L2
uniprot id: A0A6J0ACC5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

32536:FAS
gene id: 32536:FAS
uniprot id: A0A6J1YKM9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

32536:ADGRB2
gene id: 32536:ADGRB2
uniprot id: A0A6J1ZDU0
uniprot id: A0A6J1ZDU5
uniprot id: A0A6J1ZE70
uniprot id: A0A6J1ZE75
uniprot id: A0A6J1ZEY9
uniprot id: A0A6J1ZEZ7
uniprot id: A0A6J1ZFY8
uniprot id: A0A6J1ZFZ3
uniprot id: A0A6J1ZG00
uniprot id: A0A6J1ZH37
names: Subcellular Location Annotation
messages: Membrane

32536:CPA5
gene id: 32536:CPA5
uniprot id: A0A6I9ZMN8
names: Similarity
messages: Belongs to the peptidase M14 family.

32536:ACTR1A
gene id: 32536:ACTR1A
uniprot id: A0A6I9ZFS8
names: Similarity
messages: Belongs to the actin family.

32536:ANP32E
gene id: 32536:ANP32E
uniprot id: A0A6J1Z3N4
uniprot id: A0A6J1Z3Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANP32 family.
messages: Multifunctional protein that is involved in the regulation of many processes.
messages: Nucleus

32536:STC2
gene id: 32536:STC2
uniprot id: A0A6I9ZPP8
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

32536:NLRP4
gene id: 32536:NLRP4
uniprot id: A0A6J1XKS7
names: Similarity
messages: Belongs to the NLRP family.

32536:NFS1
gene id: 32536:NFS1
uniprot id: A0A6J2AB65
uniprot id: A0A6J2ABN0
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

32536:ABRAXAS1
gene id: 32536:ABRAXAS1
uniprot id: A0A6J1ZF34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Nucleus

32536:RPA3
gene id: 32536:RPA3
uniprot id: A0A6I9ZLW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

32536:KCNS2
gene id: 32536:KCNS2
uniprot id: A0A6J1ZV09
names: Subcellular Location Annotation
messages: Membrane

32536:NT5C3A
gene id: 32536:NT5C3A
uniprot id: A0A6I9ZIC1
uniprot id: A0A6I9ZJZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

32536:CD1H11orf68
gene id: 32536:CD1H11orf68
uniprot id: A0A6J1Y8X5
uniprot id: A0A6J1Y9J9
names: Similarity
messages: Belongs to the UPF0696 family.

32536:NAA35
gene id: 32536:NAA35
uniprot id: A0A6J1YG21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

32536:SSBP1
gene id: 32536:SSBP1
uniprot id: A0A6I9ZN45
uniprot id: A0A6J2ANL7
uniprot id: A0A6J2AQ42
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

32536:WNT8B
gene id: 32536:WNT8B
uniprot id: A0A6J1ZP75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

32536:NFE2L1
gene id: 32536:NFE2L1
uniprot id: A0A6J0A1T2
uniprot id: A0A6J1XBB6
uniprot id: A0A6J1XBC0
names: Similarity
messages: Belongs to the bZIP family. CNC subfamily.

32536:SPATA18
gene id: 32536:SPATA18
uniprot id: A0A6I9ZTW0
uniprot id: A0A6J1Z4P0
uniprot id: A0A6J1Z501
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIEAP family.
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion outer membrane

32536:FEZ1
gene id: 32536:FEZ1
uniprot id: A0A6J1XJI6
names: Similarity
messages: Belongs to the zygin family.

32536:PRDM15
gene id: 32536:PRDM15
uniprot id: A0A6J1XY37
names: Subcellular Location Annotation
messages: Nucleus

32536:RPL24
gene id: 32536:RPL24
uniprot id: A0A6I9ZQX8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

32536:SUPT3H
gene id: 32536:SUPT3H
uniprot id: A0A6J1Z870
names: Subcellular Location Annotation
messages: Nucleus

32536:MOG
gene id: 32536:MOG
uniprot id: A0A6J0A643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

32536:PRKCB
gene id: 32536:PRKCB
uniprot id: A0A6J1Y1W2
uniprot id: A0A6J1Y3D0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domain.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

32536:MPV17
gene id: 32536:MPV17
uniprot id: A0A6J1X778
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

32536:GNG11
gene id: 32536:GNG11
uniprot id: A0A6I9ZIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

32536:CLK3
gene id: 32536:CLK3
uniprot id: A0A6I9ZZB8
names: Similarity
messages: Belongs to the protein kinase superfamily.

32536:XKR7
gene id: 32536:XKR7
uniprot id: A0A6J2A702
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

32536:MED26
gene id: 32536:MED26
uniprot id: A0A6J1XNE3
uniprot id: A0A6J1XNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 26 family.
messages: Nucleus

32536:IL1R1
gene id: 32536:IL1R1
uniprot id: A0A6J2A5M7
uniprot id: A0A6J2A6L5
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

32536:NOTCH3
gene id: 32536:NOTCH3
uniprot id: A0A6J1YM60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

32536:DMRTA1
gene id: 32536:DMRTA1
uniprot id: A0A6J0A4X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

32536:LOC106968674
gene id: 32536:LOC106968674
uniprot id: A0A6J2ANM6
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

32536:GDNF
gene id: 32536:GDNF
uniprot id: A0A6J2AS43
uniprot id: A0A6J2AS55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

32536:TGM5
gene id: 32536:TGM5
uniprot id: A0A6I9ZK05
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

32536:NCLN
gene id: 32536:NCLN
uniprot id: A0A6J1YJN1
uniprot id: A0A6J1YKA7
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

32536:SH3RF3
gene id: 32536:SH3RF3
uniprot id: A0A6J2A9L9
names: Similarity
messages: Belongs to the SH3RF family.

32536:TIMM8B
gene id: 32536:TIMM8B
uniprot id: A0A6J0A2K5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

32536:P2RX2
gene id: 32536:P2RX2
uniprot id: A0A6J1YRX7
uniprot id: A0A6J1YTC6
uniprot id: A0A6J1YV44
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

32536:LOC106976538
gene id: 32536:LOC106976538
uniprot id: A0A6I9ZUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:VANGL1
gene id: 32536:VANGL1
uniprot id: A0A6J1ZCM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

32536:ALDH1A2
gene id: 32536:ALDH1A2
uniprot id: A0A6I9ZS56
uniprot id: A0A6I9ZSZ8
uniprot id: A0A6J2A0C9
uniprot id: A0A6J2A137
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

32536:RAX2
gene id: 32536:RAX2
uniprot id: A0A6J1YLJ1
names: Subcellular Location Annotation
messages: Nucleus

32536:DPPA5
gene id: 32536:DPPA5
uniprot id: A0A6J0A1F3
names: Similarity
messages: Belongs to the KHDC1 family.

32536:LSM3
gene id: 32536:LSM3
uniprot id: A0A6I9ZZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

32536:AP1S1
gene id: 32536:AP1S1
uniprot id: A0A6J0A7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: Membrane
messages: clathrin-coated pit

32536:CD34
gene id: 32536:CD34
uniprot id: A0A6J2AK10
uniprot id: A0A6J2AKL2
uniprot id: A0A6J2APP0
names: Subcellular Location Annotation
messages: Membrane

32536:LOC113594435
gene id: 32536:LOC113594435
uniprot id: A0A6J1XYU1
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

32536:DRAXIN
gene id: 32536:DRAXIN
uniprot id: A0A6J1ZIU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

32536:LHX5
gene id: 32536:LHX5
uniprot id: A0A6J1Y4Y9
names: Subcellular Location Annotation
messages: Nucleus

32536:LOC106971459
gene id: 32536:LOC106971459
uniprot id: A0A6J1YGV2
names: Similarity
messages: Belongs to the peptidase C1 family.

32536:SNRPC
gene id: 32536:SNRPC
uniprot id: A0A6I9ZQU3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

32536:GHRL
gene id: 32536:GHRL
uniprot id: A0A6I9ZR72
uniprot id: A0A6J1Y1B0
uniprot id: A0A6J1Y1U3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

32536:TRPT1
gene id: 32536:TRPT1
uniprot id: A0A6J0A2X1
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

32536:IFIH1
gene id: 32536:IFIH1
uniprot id: A0A6J0A664
uniprot id: A0A6J1Z3U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

32536:SPTY2D1
gene id: 32536:SPTY2D1
uniprot id: A0A6J0A920
uniprot id: A0A6J2AHA9
names: Similarity
messages: Belongs to the SPT2 family.

32536:CDKN2AIP
gene id: 32536:CDKN2AIP
uniprot id: A0A6J2AX96
names: Similarity
messages: Belongs to the CARF family.

32536:FGF12
gene id: 32536:FGF12
uniprot id: A0A6J1ZHM9
uniprot id: A0A6J1ZHZ0
uniprot id: A0A6J1ZIW1
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

32536:LXN
gene id: 32536:LXN
uniprot id: A0A6I9ZGN4
names: Similarity
messages: Belongs to the protease inhibitor I47 (latexin) family.

32536:SLC22A2
gene id: 32536:SLC22A2
uniprot id: A0A6J1Z5P4
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

32536:CACNA1D
gene id: 32536:CACNA1D
uniprot id: A0A6J1XQN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

32536:RBM42
gene id: 32536:RBM42
uniprot id: A0A6I9ZNQ4
uniprot id: A0A6J1Y7A0
uniprot id: A0A6J1Y7G4
uniprot id: A0A6J1Y8D4
names: Similarity
messages: Belongs to the RRM RBM42 family.

32536:MERTK
gene id: 32536:MERTK
uniprot id: A0A6J1XAL4
uniprot id: A0A6J1XAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

32536:UTP23
gene id: 32536:UTP23
uniprot id: A0A6I9ZV91
names: Subcellular Location Annotation
messages: nucleolus

32536:LOC106979031
gene id: 32536:LOC106979031
uniprot id: A0A6I9ZZN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:HAPLN1
gene id: 32536:HAPLN1
uniprot id: A0A6I9ZXL2
uniprot id: A0A6J1XQA7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

32536:NDRG4
gene id: 32536:NDRG4
uniprot id: A0A6J2ANW5
uniprot id: A0A6J2APC8
uniprot id: A0A6J2AQT9
uniprot id: A0A6J2ATI6
names: Similarity
messages: Belongs to the NDRG family.

32536:TMEM184C
gene id: 32536:TMEM184C
uniprot id: A0A6J0A4M3
names: Subcellular Location Annotation
messages: Membrane

32536:STON1
gene id: 32536:STON1
uniprot id: A0A6J2AEE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

32536:LOC106986327
gene id: 32536:LOC106986327
uniprot id: A0A6J0A4U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:LOC106971988
gene id: 32536:LOC106971988
uniprot id: A0A6I9ZNA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

32536:RRP1
gene id: 32536:RRP1
uniprot id: A0A6J1XYH5
names: Similarity
messages: Belongs to the RRP1 family.

32536:LOC106967049
gene id: 32536:LOC106967049
uniprot id: A0A6J2A9X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

32536:WDR44
gene id: 32536:WDR44
uniprot id: A0A6J0A4F2
uniprot id: A0A6J1YYE6
names: Subcellular Location Annotation
messages: trans-Golgi network

32536:SS18
gene id: 32536:SS18
uniprot id: A0A6I9ZVN8
uniprot id: A0A6I9ZXY0
uniprot id: A0A6I9ZYY2
uniprot id: A0A6J2A3T1
names: Similarity
messages: Belongs to the SS18 family.

32536:VIP
gene id: 32536:VIP
uniprot id: A0A6I9ZSE9
uniprot id: A0A6J1Z4U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

32536:PPP4R3A
gene id: 32536:PPP4R3A
uniprot id: A0A6J1ZXC6
uniprot id: A0A6J1ZXQ7
names: Similarity
messages: Belongs to the SMEK family.

32536:SPDYA
gene id: 32536:SPDYA
uniprot id: A0A6I9ZHD9
uniprot id: A0A6J1XA53
names: Similarity
messages: Belongs to the Speedy/Ringo family.

32536:SNRNP200
gene id: 32536:SNRNP200
uniprot id: A0A6I9ZVU7
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

32536:NMB
gene id: 32536:NMB
uniprot id: A0A6I9ZG02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Secreted
messages: neuron projection

32536:ATP6V1G3
gene id: 32536:ATP6V1G3
uniprot id: A0A6I9ZPQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

32536:CNNM3
gene id: 32536:CNNM3
uniprot id: A0A6I9ZW83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Cell membrane
messages: Membrane
messages: Metal transporter.

32536:TRNAU1AP
gene id: 32536:TRNAU1AP
uniprot id: A0A6I9ZHU0
uniprot id: A0A6I9ZKS9
uniprot id: A0A6I9ZMF7
uniprot id: A0A6J1ZEG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus

32536:TBK1
gene id: 32536:TBK1
uniprot id: A0A6J2AB48
uniprot id: A0A6J2ACC2
names: Subcellular Location Annotation
messages: Cytoplasm

32536:TECRL
gene id: 32536:TECRL
uniprot id: A0A6J0A3M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

32536:LOC106966063
gene id: 32536:LOC106966063
uniprot id: A0A6I9ZEK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:MRPL47
gene id: 32536:MRPL47
uniprot id: A0A6I9ZT54
uniprot id: A0A6J1ZI61
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

32536:ADAM18
gene id: 32536:ADAM18
uniprot id: A0A6I9ZU61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:LOC106977334
gene id: 32536:LOC106977334
uniprot id: A0A6J1Y3G9
uniprot id: A0A6J1Y4B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

32536:ATP1B4
gene id: 32536:ATP1B4
uniprot id: A0A6J1Z008
uniprot id: A0A6J1Z193
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

32536:LOC113603289
gene id: 32536:LOC113603289
uniprot id: A0A6J2AER6
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

32536:LOC106986780
gene id: 32536:LOC106986780
uniprot id: A0A6J0A5C3
uniprot id: A0A6J0A5H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

32536:CTNNAL1
gene id: 32536:CTNNAL1
uniprot id: A0A6J1XDN6
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

32536:SUCNR1
gene id: 32536:SUCNR1
uniprot id: A0A6J1ZL47
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

32536:ITPKC
gene id: 32536:ITPKC
uniprot id: A0A6I9ZW86
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

32536:SLC14A2
gene id: 32536:SLC14A2
uniprot id: A0A6I9ZLE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

32536:HACD3
gene id: 32536:HACD3
uniprot id: A0A6J0A168
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

32536:MYOZ3
gene id: 32536:MYOZ3
uniprot id: A0A6J0A3R6
uniprot id: A0A6J2AX86
names: Similarity
messages: Belongs to the myozenin family.

32536:DPYSL3
gene id: 32536:DPYSL3
uniprot id: A0A6J0A729
uniprot id: A0A6J1XZF4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

32536:SLC2A2
gene id: 32536:SLC2A2
uniprot id: A0A6J0A9J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

32536:TMEM234
gene id: 32536:TMEM234
uniprot id: A0A6J0A3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

32536:PBRM1
gene id: 32536:PBRM1
uniprot id: A0A6J1XQA4
uniprot id: A0A6J1XQB3
uniprot id: A0A6J1XQC5
uniprot id: A0A6J1XQJ7
uniprot id: A0A6J1XQJ8
uniprot id: A0A6J1XQK2
uniprot id: A0A6J1XQL6
names: Subcellular Location Annotation
messages: Nucleus

32536:MPDU1
gene id: 32536:MPDU1
uniprot id: A0A6I9ZKW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

32536:TMEM151A
gene id: 32536:TMEM151A
uniprot id: A0A6J1Y9I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM151 family.
messages: Membrane

32536:AGPAT5
gene id: 32536:AGPAT5
uniprot id: A0A6J1YNU8
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

32536:SPACA4
gene id: 32536:SPACA4
uniprot id: A0A6J0A869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPACA4/bouncer family.
messages: Cell membrane
messages: Membrane

32536:RPRD1A
gene id: 32536:RPRD1A
uniprot id: A0A6J0A2I7
uniprot id: A0A6J0A552
uniprot id: A0A6J0A686
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex.
messages: Belongs to the UPF0400 (RTT103) family.
messages: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
messages: Nucleus

32536:ARPC1A
gene id: 32536:ARPC1A
uniprot id: A0A6J1XZM7
names: Function
names: Similarity
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

32536:PEX16
gene id: 32536:PEX16
uniprot id: A0A6J2AFM4
uniprot id: A0A6J2AJ95
uniprot id: A0A6J2AJQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

32536:RSL24D1
gene id: 32536:RSL24D1
uniprot id: A0A6J0AAW3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

32536:LOC106986185
gene id: 32536:LOC106986185
uniprot id: A0A6J0A4L3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

32536:HOXB4
gene id: 32536:HOXB4
uniprot id: A0A6J1XBD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

32536:NAA38
gene id: 32536:NAA38
uniprot id: A0A6J1YEC0
names: Function
names: Similarity
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.

32536:VPS8
gene id: 32536:VPS8
uniprot id: A0A6J1ZI68
uniprot id: A0A6J1ZK90
names: Similarity
messages: Belongs to the VPS8 family.

32536:CDO1
gene id: 32536:CDO1
uniprot id: A0A6J2AVY7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

32536:TRPV4
gene id: 32536:TRPV4
uniprot id: A0A6J1Y4F4
names: Subcellular Location Annotation
messages: Membrane

32536:WASHC5
gene id: 32536:WASHC5
uniprot id: A0A6J0A8T6
names: Similarity
messages: Belongs to the strumpellin family.

32536:SMARCA4
gene id: 32536:SMARCA4
uniprot id: A0A6J1YLN2
uniprot id: A0A6J1YLN7
uniprot id: A0A6J1YLP1
uniprot id: A0A6J1YLP6
uniprot id: A0A6J1YMW2
uniprot id: A0A6J1YN98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

32536:NELFCD
gene id: 32536:NELFCD
uniprot id: A0A6J1YCZ1
uniprot id: A0A6J1YDP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

32536:LOC106986541
gene id: 32536:LOC106986541
uniprot id: A0A6J0A517
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.