323848:NMUL RS04060
gene id: 323848:NMUL_RS04060
uniprot id: A0A1H5SZ78
uniprot id: Q2YAZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

323848:NMUL RS09820
gene id: 323848:NMUL_RS09820
uniprot id: Q2Y7V2
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

323848:NMUL RS13745
gene id: 323848:NMUL_RS13745
uniprot id: Q2Y5P5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

323848:NMUL RS09125
gene id: 323848:NMUL_RS09125
uniprot id: Q2Y884
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03720
gene id: 323848:NMUL_RS03720
uniprot id: A0A1H5SX03
uniprot id: Q2YB59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS06510
gene id: 323848:NMUL_RS06510
uniprot id: A0A1H5VRW3
uniprot id: Q2Y9M8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

323848:NMUL RS02030
gene id: 323848:NMUL_RS02030
uniprot id: A0A1H5RNS4
uniprot id: Q2YC27
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

323848:NMUL RS02620
gene id: 323848:NMUL_RS02620
uniprot id: Q2YBR2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

323848:NMUL RS02115
gene id: 323848:NMUL_RS02115
uniprot id: Q2YC11
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS03985
gene id: 323848:NMUL_RS03985
uniprot id: A0A1H5SZ96
uniprot id: Q2YAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

323848:NMUL RS13640
gene id: 323848:NMUL_RS13640
uniprot id: Q2Y5R6
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

323848:NMUL RS02000
gene id: 323848:NMUL_RS02000
uniprot id: Q2YC33
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

323848:NMUL RS13300
gene id: 323848:NMUL_RS13300
uniprot id: Q2Y5X9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

323848:NMUL RS10155
gene id: 323848:NMUL_RS10155
uniprot id: Q2Y7N5
names: Similarity
messages: Belongs to the aspartokinase family.

323848:NMUL RS00530
gene id: 323848:NMUL_RS00530
uniprot id: Q2YCW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323848:NMUL RS02550
gene id: 323848:NMUL_RS02550
uniprot id: A0A1H5RUQ9
uniprot id: Q2YBS4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

323848:NMUL RS09640
gene id: 323848:NMUL_RS09640
uniprot id: Q2Y7Y5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS02865
gene id: 323848:NMUL_RS02865
uniprot id: Q2YBM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

323848:NMUL RS01375
gene id: 323848:NMUL_RS01375
uniprot id: Q2YCF2
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

323848:NMUL RS04570
gene id: 323848:NMUL_RS04570
uniprot id: Q2YAQ6
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

323848:NMUL RS13840
gene id: 323848:NMUL_RS13840
uniprot id: Q2Y5M7
names: Similarity
messages: Belongs to the DEAD box helicase family.

323848:NMUL RS04120
gene id: 323848:NMUL_RS04120
uniprot id: A0A1H5T1Y0
uniprot id: Q2YAY6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

323848:NMUL RS02215
gene id: 323848:NMUL_RS02215
uniprot id: A0A1H5RQM7
uniprot id: Q2YBZ1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS04090
gene id: 323848:NMUL_RS04090
uniprot id: A0A1H5T1I6
uniprot id: Q2YAZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

323848:NMUL RS11630
gene id: 323848:NMUL_RS11630
uniprot id: Q2Y6V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

323848:NMUL RS02060
gene id: 323848:NMUL_RS02060
uniprot id: Q2YC21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

323848:NMUL RS07070
gene id: 323848:NMUL_RS07070
uniprot id: Q2Y9C5
names: Similarity
messages: Belongs to the type III secretion exporter family.

323848:NMUL RS10190
gene id: 323848:NMUL_RS10190
uniprot id: A0A1H5TA74
uniprot id: Q2Y7M8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

323848:NMUL RS00535
gene id: 323848:NMUL_RS00535
uniprot id: Q2YCW0
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

323848:NMUL RS00465
gene id: 323848:NMUL_RS00465
uniprot id: Q2YCX4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

323848:NMUL RS05595
gene id: 323848:NMUL_RS05595
uniprot id: Q2YA54
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

323848:NMUL RS11145
gene id: 323848:NMUL_RS11145
uniprot id: A0A1H5VH76
uniprot id: Q2Y742
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

323848:NMUL RS01695
gene id: 323848:NMUL_RS01695
uniprot id: A0A1H5RLE6
uniprot id: Q2YC92
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

323848:NMUL RS04180
gene id: 323848:NMUL_RS04180
uniprot id: A0A1H5T2I2
uniprot id: Q2YAX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

323848:NMUL RS13980
gene id: 323848:NMUL_RS13980
uniprot id: Q2Y5K1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

323848:NMUL RS09650
gene id: 323848:NMUL_RS09650
uniprot id: A0A1H5TH84
uniprot id: Q2Y7Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS13390
gene id: 323848:NMUL_RS13390
uniprot id: Q2Y5W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323848:NMUL RS01015
gene id: 323848:NMUL_RS01015
uniprot id: A0A1H5V4V5
uniprot id: Q2YCL8
names: Similarity
messages: Belongs to the UPF0102 family.

323848:NMUL RS08160
gene id: 323848:NMUL_RS08160
uniprot id: Q2Y8R2
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS13385
gene id: 323848:NMUL_RS13385
uniprot id: Q2Y5W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323848:NMUL RS09970
gene id: 323848:NMUL_RS09970
uniprot id: Q2Y7S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

323848:NMUL RS13130
gene id: 323848:NMUL_RS13130
uniprot id: Q2Y613
names: Similarity
messages: Belongs to the asparagine synthetase family.

323848:NMUL RS10010
gene id: 323848:NMUL_RS10010
uniprot id: A0A1H5TCL4
uniprot id: Q2Y7R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

323848:NMUL RS14425
gene id: 323848:NMUL_RS14425
uniprot id: Q2Y5B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

323848:NMUL RS00495
gene id: 323848:NMUL_RS00495
uniprot id: Q2YCW8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323848:NMUL RS14025
gene id: 323848:NMUL_RS14025
uniprot id: Q2Y5J2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS01470
gene id: 323848:NMUL_RS01470
uniprot id: Q2YCD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

323848:NMUL RS03240
gene id: 323848:NMUL_RS03240
uniprot id: Q2YBF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS03765
gene id: 323848:NMUL_RS03765
uniprot id: Q2YB50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

323848:NMUL RS09215
gene id: 323848:NMUL_RS09215
uniprot id: Q2Y866
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13495
gene id: 323848:NMUL_RS13495
uniprot id: Q2Y5U4
names: Similarity
messages: Belongs to the GSP E family.

323848:NMUL RS14100
gene id: 323848:NMUL_RS14100
uniprot id: A0A1H5UXJ4
uniprot id: Q2Y5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

323848:NMUL RS06455
gene id: 323848:NMUL_RS06455
uniprot id: Q2Y9N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS08755
gene id: 323848:NMUL_RS08755
uniprot id: Q2Y8F4
names: Similarity
messages: Belongs to the HypE family.

323848:NMUL RS06320
gene id: 323848:NMUL_RS06320
uniprot id: Q2Y9R6
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

323848:NMUL RS06875
gene id: 323848:NMUL_RS06875
uniprot id: Q2Y9G3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

323848:NMUL RS03880
gene id: 323848:NMUL_RS03880
uniprot id: A0A1H5SWX3
uniprot id: Q2YB30
names: Similarity
messages: Belongs to the UPF0145 family.

323848:NMUL RS03065
gene id: 323848:NMUL_RS03065
uniprot id: Q2YBI3
names: Similarity
messages: Belongs to the YggT family.

323848:NMUL RS02350
gene id: 323848:NMUL_RS02350
uniprot id: A0A1H5RS45
uniprot id: Q2YBW4
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

323848:NMUL RS02405
gene id: 323848:NMUL_RS02405
uniprot id: Q2YBV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

323848:NMUL RS05915
gene id: 323848:NMUL_RS05915
uniprot id: A0A1H5ULM8
uniprot id: Q2Y9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

323848:NMUL RS08355
gene id: 323848:NMUL_RS08355
uniprot id: A0A1H5X9S3
uniprot id: Q2Y8M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

323848:NMUL RS02665
gene id: 323848:NMUL_RS02665
uniprot id: Q2YBQ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

323848:NMUL RS04680
gene id: 323848:NMUL_RS04680
uniprot id: Q2YAN3
names: Similarity
messages: Belongs to the RutC family.

323848:NMUL RS08740
gene id: 323848:NMUL_RS08740
uniprot id: Q2Y8F7
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

323848:NMUL RS13225
gene id: 323848:NMUL_RS13225
uniprot id: Q2Y5Z4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

323848:NMUL RS04240
gene id: 323848:NMUL_RS04240
uniprot id: Q2YA33
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

323848:NMUL RS13760
gene id: 323848:NMUL_RS13760
uniprot id: A0A1H5WJ50
uniprot id: Q2Y5P2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

323848:NMUL RS12795
gene id: 323848:NMUL_RS12795
uniprot id: A0A1H5VUD3
uniprot id: Q2Y681
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

323848:NMUL RS04275
gene id: 323848:NMUL_RS04275
uniprot id: Q2YAV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323848:NMUL RS05820
gene id: 323848:NMUL_RS05820
uniprot id: Q2YA11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS05655
gene id: 323848:NMUL_RS05655
uniprot id: Q2YA42
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

323848:NMUL RS01055
gene id: 323848:NMUL_RS01055
uniprot id: Q2YCL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

323848:NMUL RS04560
gene id: 323848:NMUL_RS04560
uniprot id: Q2YAQ8
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

323848:NMUL RS13570
gene id: 323848:NMUL_RS13570
uniprot id: Q2Y5T0
names: Similarity
messages: Belongs to the Gfa family.

323848:NMUL RS09450
gene id: 323848:NMUL_RS09450
uniprot id: Q2Y820
names: Similarity
messages: Belongs to the glutamate synthase family.

323848:NMUL RS05355
gene id: 323848:NMUL_RS05355
uniprot id: Q2YAA2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

323848:NMUL RS05325
gene id: 323848:NMUL_RS05325
uniprot id: Q2YAA8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

323848:NMUL RS00515
gene id: 323848:NMUL_RS00515
uniprot id: Q2YCW4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

323848:NMUL RS01615
gene id: 323848:NMUL_RS01615
uniprot id: Q2YCA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

323848:NMUL RS05880
gene id: 323848:NMUL_RS05880
uniprot id: Q2Y9Z9
names: Similarity
messages: Belongs to the peptidase S41A family.

323848:NMUL RS06235
gene id: 323848:NMUL_RS06235
uniprot id: Q2Y9T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS01850
gene id: 323848:NMUL_RS01850
uniprot id: A0A1H5RM90
uniprot id: Q2YC62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

323848:NMUL RS13040
gene id: 323848:NMUL_RS13040
uniprot id: Q2Y632
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

323848:NMUL RS13025
gene id: 323848:NMUL_RS13025
uniprot id: A0A1H5TUK6
uniprot id: Q2Y635
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS05945
gene id: 323848:NMUL_RS05945
uniprot id: A0A1H5UPG9
uniprot id: Q2Y9Y6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

323848:NMUL RS13230
gene id: 323848:NMUL_RS13230
uniprot id: Q2Y5Z3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

323848:NMUL RS11625
gene id: 323848:NMUL_RS11625
uniprot id: Q2Y6V1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS10685
gene id: 323848:NMUL_RS10685
uniprot id: Q2Y7D4
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

323848:NMUL RS01235
gene id: 323848:NMUL_RS01235
uniprot id: A0A1H5V498
uniprot id: Q2YCH7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

323848:NMUL RS06740
gene id: 323848:NMUL_RS06740
uniprot id: Q2Y9I8
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS10170
gene id: 323848:NMUL_RS10170
uniprot id: Q2Y7N2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

323848:NMUL RS02245
gene id: 323848:NMUL_RS02245
uniprot id: Q2YBY5
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

323848:NMUL RS05740
gene id: 323848:NMUL_RS05740
uniprot id: Q2YA27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS00220
gene id: 323848:NMUL_RS00220
uniprot id: Q2YD19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS02965
gene id: 323848:NMUL_RS02965
uniprot id: A0A1H5WF73
uniprot id: Q2YBK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

323848:NMUL RS02765
gene id: 323848:NMUL_RS02765
uniprot id: Q2YBP0
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

323848:NMUL RS08525
gene id: 323848:NMUL_RS08525
uniprot id: Q2Y8J7
names: Similarity
messages: Belongs to the 6-phosphogluconate dehydrogenase family.

323848:NMUL RS03890
gene id: 323848:NMUL_RS03890
uniprot id: Q2YB28
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323848:NMUL RS05010
gene id: 323848:NMUL_RS05010
uniprot id: Q2YAG8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS03345
gene id: 323848:NMUL_RS03345
uniprot id: Q2YBD1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS01760
gene id: 323848:NMUL_RS01760
uniprot id: Q2YC80
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

323848:NMUL RS08520
gene id: 323848:NMUL_RS08520
uniprot id: Q2Y8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

323848:NMUL RS00270
gene id: 323848:NMUL_RS00270
uniprot id: Q2YD09
names: Similarity
messages: Belongs to the thioredoxin family.

323848:NMUL RS12160
gene id: 323848:NMUL_RS12160
uniprot id: Q2Y6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS06045
gene id: 323848:NMUL_RS06045
uniprot id: Q2Y9W9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

323848:NMUL RS02325
gene id: 323848:NMUL_RS02325
uniprot id: Q2YBW9
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

323848:NMUL RS12235
gene id: 323848:NMUL_RS12235
uniprot id: A0A1H5XH99
uniprot id: Q2Y6I5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

323848:NMUL RS13885
gene id: 323848:NMUL_RS13885
uniprot id: Q2Y5L9
names: Similarity
messages: Belongs to the SCO1/2 family.

323848:NMUL RS06975
gene id: 323848:NMUL_RS06975
uniprot id: Q2Y9E4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

323848:NMUL RS03795
gene id: 323848:NMUL_RS03795
uniprot id: A0A1H5SVW5
uniprot id: Q2YB46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

323848:NMUL RS05800
gene id: 323848:NMUL_RS05800
uniprot id: Q2YA15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323848:NMUL RS00215
gene id: 323848:NMUL_RS00215
uniprot id: Q2YD20
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS14325
gene id: 323848:NMUL_RS14325
uniprot id: Q2Y5D2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

323848:NMUL RS14200
gene id: 323848:NMUL_RS14200
uniprot id: Q2Y5F7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

323848:NMUL RS04305
gene id: 323848:NMUL_RS04305
uniprot id: A0A1H5XTZ6
uniprot id: Q2YAV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

323848:NMUL RS01415
gene id: 323848:NMUL_RS01415
uniprot id: Q2YCE6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

323848:NMUL RS07730
gene id: 323848:NMUL_RS07730
uniprot id: Q2Y8Z7
names: Similarity
messages: Belongs to the pirin family.

323848:NMUL RS10870
gene id: 323848:NMUL_RS10870
uniprot id: A0A1H5X2R0
uniprot id: Q2Y797
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

323848:NMUL RS03105
gene id: 323848:NMUL_RS03105
uniprot id: A0A1H5WDZ3
uniprot id: Q2YBH5
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

323848:NMUL RS07955
gene id: 323848:NMUL_RS07955
uniprot id: Q2Y8V3
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

323848:NMUL RS01670
gene id: 323848:NMUL_RS01670
uniprot id: Q2YC97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. MrdB/RodA subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell wall elongation.

323848:NMUL RS03770
gene id: 323848:NMUL_RS03770
uniprot id: Q2YB49
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

323848:NMUL RS02530
gene id: 323848:NMUL_RS02530
uniprot id: A0A1H5RUZ7
uniprot id: Q2YBS8
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

323848:NMUL RS02470
gene id: 323848:NMUL_RS02470
uniprot id: Q2YBU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

323848:NMUL RS05750
gene id: 323848:NMUL_RS05750
uniprot id: A0A1H5ULG8
uniprot id: Q2YA25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS10280
gene id: 323848:NMUL_RS10280
uniprot id: A0A1H5T9B1
uniprot id: Q2Y7L1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS09635
gene id: 323848:NMUL_RS09635
uniprot id: Q2Y7Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

323848:NMUL RS12640
gene id: 323848:NMUL_RS12640
uniprot id: Q2Y6A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

323848:NMUL RS05425
gene id: 323848:NMUL_RS05425
uniprot id: Q2YA88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

323848:NMUL RS11040
gene id: 323848:NMUL_RS11040
uniprot id: A0A1H5VI87
uniprot id: Q2Y763
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

323848:NMUL RS13470
gene id: 323848:NMUL_RS13470
uniprot id: Q2Y5U9
names: Similarity
messages: Belongs to the bacterial secretin family.

323848:NMUL RS01705
gene id: 323848:NMUL_RS01705
uniprot id: A0A1H5RL94
uniprot id: Q2YC90
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

323848:NMUL RS02985
gene id: 323848:NMUL_RS02985
uniprot id: A0A1H5WFB6
uniprot id: Q2YBJ8
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

323848:NMUL RS05965
gene id: 323848:NMUL_RS05965
uniprot id: Q2Y9Y3
names: Subcellular Location Annotation
messages: Cytoplasm

323848:NMUL RS05000
gene id: 323848:NMUL_RS05000
uniprot id: Q2YAH0
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03540
gene id: 323848:NMUL_RS03540
uniprot id: A0A1H5ST70
uniprot id: Q2YB94
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

323848:NMUL RS07155
gene id: 323848:NMUL_RS07155
uniprot id: Q2Y9A8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

323848:NMUL RS01150
gene id: 323848:NMUL_RS01150
uniprot id: A0A1H5V581
uniprot id: Q2YCJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

323848:NMUL RS01285
gene id: 323848:NMUL_RS01285
uniprot id: Q2YCH0
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS11790
gene id: 323848:NMUL_RS11790
uniprot id: Q2Y6S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm

323848:NMUL RS05420
gene id: 323848:NMUL_RS05420
uniprot id: Q2YA89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323848:NMUL RS03920
gene id: 323848:NMUL_RS03920
uniprot id: A0A1H5SXK2
uniprot id: Q2YB22
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

323848:NMUL RS09515
gene id: 323848:NMUL_RS09515
uniprot id: A0A1H5WBK3
uniprot id: Q2Y808
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

323848:NMUL RS11000
gene id: 323848:NMUL_RS11000
uniprot id: Q2Y771
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS06385
gene id: 323848:NMUL_RS06385
uniprot id: Q2Y9Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323848:NMUL RS05715
gene id: 323848:NMUL_RS05715
uniprot id: Q2YA31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS07475
gene id: 323848:NMUL_RS07475
uniprot id: Q2Y948
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS14250
gene id: 323848:NMUL_RS14250
uniprot id: Q2Y5E7
names: Similarity
messages: Belongs to the peptidase M16 family.

323848:NMUL RS06675
gene id: 323848:NMUL_RS06675
uniprot id: Q2Y9J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

323848:NMUL RS09465
gene id: 323848:NMUL_RS09465
uniprot id: Q2Y817
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03950
gene id: 323848:NMUL_RS03950
uniprot id: Q2YB16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

323848:NMUL RS12210
gene id: 323848:NMUL_RS12210
uniprot id: A0A1H5XH64
uniprot id: Q2Y6I9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

323848:NMUL RS04285
gene id: 323848:NMUL_RS04285
uniprot id: A0A1H5XU59
uniprot id: Q2YAV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323848:NMUL RS05135
gene id: 323848:NMUL_RS05135
uniprot id: Q2YAE4
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

323848:NMUL RS05030
gene id: 323848:NMUL_RS05030
uniprot id: Q2YAG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323848:NMUL RS06985
gene id: 323848:NMUL_RS06985
uniprot id: Q2Y9E2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323848:NMUL RS10035
gene id: 323848:NMUL_RS10035
uniprot id: Q2Y7Q9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS12080
gene id: 323848:NMUL_RS12080
uniprot id: Q2Y6L3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

323848:NMUL RS08500
gene id: 323848:NMUL_RS08500
uniprot id: Q2Y8K2
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

323848:NMUL RS00355
gene id: 323848:NMUL_RS00355
uniprot id: Q2YCZ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

323848:NMUL RS08675
gene id: 323848:NMUL_RS08675
uniprot id: Q2Y8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

323848:NMUL RS14145
gene id: 323848:NMUL_RS14145
uniprot id: Q2Y5G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323848:NMUL RS05175
gene id: 323848:NMUL_RS05175
uniprot id: A0A1H5SFN3
uniprot id: Q2YAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

323848:NMUL RS13830
gene id: 323848:NMUL_RS13830
uniprot id: Q2Y5M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

323848:NMUL RS04295
gene id: 323848:NMUL_RS04295
uniprot id: A0A1H5XTY5
uniprot id: Q2YAV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

323848:NMUL RS00445
gene id: 323848:NMUL_RS00445
uniprot id: Q2YCX8
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

323848:NMUL RS09560
gene id: 323848:NMUL_RS09560
uniprot id: Q2Y7Z9
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

323848:NMUL RS06345
gene id: 323848:NMUL_RS06345
uniprot id: Q2Y9R0
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

323848:NMUL RS03780
gene id: 323848:NMUL_RS03780
uniprot id: A0A1H5SW00
uniprot id: Q2YB47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

323848:NMUL RS03715
gene id: 323848:NMUL_RS03715
uniprot id: Q2YB60
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

323848:NMUL RS00255
gene id: 323848:NMUL_RS00255
uniprot id: Q2YD12
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

323848:NMUL RS12330
gene id: 323848:NMUL_RS12330
uniprot id: Q2Y6G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS10400
gene id: 323848:NMUL_RS10400
uniprot id: A0A1H5T7U0
uniprot id: Q2Y7I9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

323848:NMUL RS10055
gene id: 323848:NMUL_RS10055
uniprot id: Q2Y7Q5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

323848:NMUL RS02195
gene id: 323848:NMUL_RS02195
uniprot id: Q2YBZ5
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS05905
gene id: 323848:NMUL_RS05905
uniprot id: A0A1H5ULH1
uniprot id: Q2Y9Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

323848:NMUL RS09225
gene id: 323848:NMUL_RS09225
uniprot id: A0A1H5V8P4
uniprot id: Q2Y864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

323848:NMUL RS07470
gene id: 323848:NMUL_RS07470
uniprot id: Q2Y949
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS01815
gene id: 323848:NMUL_RS01815
uniprot id: Q2YC69
names: PTM
messages: Binds 1 heme c group covalently per subunit.

323848:NMUL RS10040
gene id: 323848:NMUL_RS10040
uniprot id: A0A1H5TCB9
uniprot id: Q2Y7Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS09190
gene id: 323848:NMUL_RS09190
uniprot id: Q2Y871
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

323848:NMUL RS01625
gene id: 323848:NMUL_RS01625
uniprot id: A0A1H5RKV9
uniprot id: Q2YCA6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

323848:NMUL RS07090
gene id: 323848:NMUL_RS07090
uniprot id: Q2Y9C1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

323848:NMUL RS09710
gene id: 323848:NMUL_RS09710
uniprot id: Q2Y7X1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

323848:NMUL RS04155
gene id: 323848:NMUL_RS04155
uniprot id: A0A1H5T072
uniprot id: Q2YAX9
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

323848:NMUL RS06895
gene id: 323848:NMUL_RS06895
uniprot id: Q2Y9F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

323848:NMUL RS01915
gene id: 323848:NMUL_RS01915
uniprot id: A0A1H5RN07
uniprot id: Q2YC50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

323848:NMUL RS02705
gene id: 323848:NMUL_RS02705
uniprot id: A0A1H5RWD8
uniprot id: Q2YBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

323848:NMUL RS13065
gene id: 323848:NMUL_RS13065
uniprot id: A0A1H5TU46
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03740
gene id: 323848:NMUL_RS03740
uniprot id: Q2YB55
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS04100
gene id: 323848:NMUL_RS04100
uniprot id: A0A1H5SZJ0
uniprot id: Q2YAZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

323848:NMUL RS05375
gene id: 323848:NMUL_RS05375
uniprot id: A0A1H5SK07
uniprot id: Q2YA98
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS11060
gene id: 323848:NMUL_RS11060
uniprot id: Q2Y759
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

323848:NMUL RS12780
gene id: 323848:NMUL_RS12780
uniprot id: Q2Y684
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323848:NMUL RS11935
gene id: 323848:NMUL_RS11935
uniprot id: A0A1H5U2V6
uniprot id: Q2Y6P3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS13605
gene id: 323848:NMUL_RS13605
uniprot id: A0A1H5WHN5
uniprot id: Q2Y5S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

323848:NMUL RS05415
gene id: 323848:NMUL_RS05415
uniprot id: Q2YA90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323848:NMUL RS08735
gene id: 323848:NMUL_RS08735
uniprot id: A0A1H5WLR4
uniprot id: Q2Y8F8
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

323848:NMUL RS05565
gene id: 323848:NMUL_RS05565
uniprot id: Q2YA60
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

323848:NMUL RS10140
gene id: 323848:NMUL_RS10140
uniprot id: Q2Y7N7
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.

323848:NMUL RS03495
gene id: 323848:NMUL_RS03495
uniprot id: Q2YBA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

323848:NMUL RS08555
gene id: 323848:NMUL_RS08555
uniprot id: Q2Y8J3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

323848:NMUL RS08670
gene id: 323848:NMUL_RS08670
uniprot id: Q2Y8H0
names: Function
names: Similarity
messages: Belongs to the ATPase gamma chain family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

323848:NMUL RS07950
gene id: 323848:NMUL_RS07950
uniprot id: Q2Y8V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

323848:NMUL RS06020
gene id: 323848:NMUL_RS06020
uniprot id: Q2Y9X4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

323848:NMUL RS00365
gene id: 323848:NMUL_RS00365
uniprot id: A0A1H5XZV7
uniprot id: Q2YCZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS03405
gene id: 323848:NMUL_RS03405
uniprot id: Q2YBB9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

323848:NMUL RS11420
gene id: 323848:NMUL_RS11420
uniprot id: Q2Y6Y9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS11690
gene id: 323848:NMUL_RS11690
uniprot id: A0A1H5U5M1
uniprot id: Q2Y6T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

323848:NMUL RS00670
gene id: 323848:NMUL_RS00670
uniprot id: Q2YCT1
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

323848:NMUL RS11930
gene id: 323848:NMUL_RS11930
uniprot id: A0A1H5U2X9
uniprot id: Q2Y6P4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

323848:NMUL RS00025
gene id: 323848:NMUL_RS00025
uniprot id: A0A1H5WPK7
uniprot id: Q2YD57
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

323848:NMUL RS14330
gene id: 323848:NMUL_RS14330
uniprot id: Q2Y5D1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

323848:NMUL RS09245
gene id: 323848:NMUL_RS09245
uniprot id: Q2Y860
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

323848:NMUL RS12355
gene id: 323848:NMUL_RS12355
uniprot id: Q2Y6G1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

323848:NMUL RS02395
gene id: 323848:NMUL_RS02395
uniprot id: Q2YBV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS12930
gene id: 323848:NMUL_RS12930
uniprot id: A0A1H5TWE2
uniprot id: Q2Y654
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

323848:NMUL RS10195
gene id: 323848:NMUL_RS10195
uniprot id: A0A1H5TAC5
uniprot id: Q2Y7M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

323848:NMUL RS01640
gene id: 323848:NMUL_RS01640
uniprot id: A0A1H5RNB3
uniprot id: Q2YCA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

323848:NMUL RS09995
gene id: 323848:NMUL_RS09995
uniprot id: Q2Y7R7
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

323848:NMUL RS02855
gene id: 323848:NMUL_RS02855
uniprot id: A0A1H5S095
uniprot id: Q2YBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

323848:NMUL RS03020
gene id: 323848:NMUL_RS03020
uniprot id: A0A1H5WFG7
uniprot id: Q2YBJ1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

323848:NMUL RS06530
gene id: 323848:NMUL_RS06530
uniprot id: A0A1H5VPT6
uniprot id: Q2Y9M4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

323848:NMUL RS01700
gene id: 323848:NMUL_RS01700
uniprot id: A0A1H5RMZ8
uniprot id: Q2YC91
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

323848:NMUL RS13000
gene id: 323848:NMUL_RS13000
uniprot id: A0A1H5TV89
uniprot id: Q2Y640
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

323848:NMUL RS00265
gene id: 323848:NMUL_RS00265
uniprot id: A0A1H5Y9U0
uniprot id: Q2YD10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

323848:NMUL RS02070
gene id: 323848:NMUL_RS02070
uniprot id: A0A1H5RP98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

323848:NMUL RS00370
gene id: 323848:NMUL_RS00370
uniprot id: A0A1H5XZ03
uniprot id: Q2YCZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

323848:NMUL RS02975
gene id: 323848:NMUL_RS02975
uniprot id: Q2YBK0
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

323848:NMUL RS05755
gene id: 323848:NMUL_RS05755
uniprot id: A0A1H5UJT9
uniprot id: Q2YA24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS04030
gene id: 323848:NMUL_RS04030
uniprot id: A0A1H5SYR6
uniprot id: Q2YB04
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323848:NMUL RS05455
gene id: 323848:NMUL_RS05455
uniprot id: Q2YA82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

323848:NMUL RS11565
gene id: 323848:NMUL_RS11565
uniprot id: A0A1H5U8U0
uniprot id: Q2Y6W3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

323848:NMUL RS05930
gene id: 323848:NMUL_RS05930
uniprot id: A0A1H5ULZ6
uniprot id: Q2Y9Y9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

323848:NMUL RS09510
gene id: 323848:NMUL_RS09510
uniprot id: A0A1H5WBG3
uniprot id: Q2Y809
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

323848:NMUL RS05550
gene id: 323848:NMUL_RS05550
uniprot id: Q2YA63
names: Similarity
messages: Belongs to the peptidase U62 family.

323848:NMUL RS08320
gene id: 323848:NMUL_RS08320
uniprot id: Q2Y8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS06475
gene id: 323848:NMUL_RS06475
uniprot id: Q2Y9N4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the transcriptional regulatory CopG/NikR family.
messages: Binds 1 nickel ion per subunit.
messages: Transcriptional regulator.

323848:NMUL RS04665
gene id: 323848:NMUL_RS04665
uniprot id: Q2YAN6
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

323848:NMUL RS10865
gene id: 323848:NMUL_RS10865
uniprot id: Q2Y798
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

323848:NMUL RS05940
gene id: 323848:NMUL_RS05940
uniprot id: A0A1H5UNQ6
uniprot id: Q2Y9Y7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

323848:NMUL RS04265
gene id: 323848:NMUL_RS04265
uniprot id: Q2YAV8
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

323848:NMUL RS07905
gene id: 323848:NMUL_RS07905
uniprot id: Q2Y8W3
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS09120
gene id: 323848:NMUL_RS09120
uniprot id: Q2Y885
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323848:NMUL RS08765
gene id: 323848:NMUL_RS08765
uniprot id: Q2Y8F2
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.

323848:NMUL RS02710
gene id: 323848:NMUL_RS02710
uniprot id: Q2YBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

323848:NMUL RS12665
gene id: 323848:NMUL_RS12665
uniprot id: A0A1H5VSZ7
uniprot id: Q2Y6A3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

323848:NMUL RS00795
gene id: 323848:NMUL_RS00795
uniprot id: A0A1H5XFN0
uniprot id: Q2YCR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

323848:NMUL RS05640
gene id: 323848:NMUL_RS05640
uniprot id: Q2YA45
names: Similarity
messages: Belongs to the fabD family.

323848:NMUL RS00010
gene id: 323848:NMUL_RS00010
uniprot id: Q2YD60
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

323848:NMUL RS14450
gene id: 323848:NMUL_RS14450
uniprot id: A0A1H5WPL5
uniprot id: Q2Y5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

323848:NMUL RS14420
gene id: 323848:NMUL_RS14420
uniprot id: A0A1H5WNY4
uniprot id: Q2Y5B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

323848:NMUL RS04685
gene id: 323848:NMUL_RS04685
uniprot id: A0A1H5SB44
uniprot id: Q2YAN2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS08875
gene id: 323848:NMUL_RS08875
uniprot id: Q2Y8D1
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

323848:NMUL RS11230
gene id: 323848:NMUL_RS11230
uniprot id: Q2Y725
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13045
gene id: 323848:NMUL_RS13045
uniprot id: Q2Y631
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323848:NMUL RS12345
gene id: 323848:NMUL_RS12345
uniprot id: Q2Y6G3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

323848:NMUL RS12955
gene id: 323848:NMUL_RS12955
uniprot id: Q2Y649
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

323848:NMUL RS14280
gene id: 323848:NMUL_RS14280
uniprot id: Q2Y5E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS09930
gene id: 323848:NMUL_RS09930
uniprot id: Q2Y7T0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

323848:NMUL RS14260
gene id: 323848:NMUL_RS14260
uniprot id: Q2Y5E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

323848:NMUL RS05675
gene id: 323848:NMUL_RS05675
uniprot id: Q2YA38
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

323848:NMUL RS07735
gene id: 323848:NMUL_RS07735
uniprot id: Q2Y8Z6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323848:NMUL RS05635
gene id: 323848:NMUL_RS05635
uniprot id: A0A1H5SKR8
uniprot id: Q2YA46
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

323848:NMUL RS03995
gene id: 323848:NMUL_RS03995
uniprot id: Q2YB11
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS04145
gene id: 323848:NMUL_RS04145
uniprot id: A0A1H5T234
uniprot id: Q2YAY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

323848:NMUL RS09185
gene id: 323848:NMUL_RS09185
uniprot id: Q2Y872
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

323848:NMUL RS04140
gene id: 323848:NMUL_RS04140
uniprot id: A0A1H5T026
uniprot id: Q2YAY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

323848:NMUL RS02280
gene id: 323848:NMUL_RS02280
uniprot id: Q2YBX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

323848:NMUL RS01685
gene id: 323848:NMUL_RS01685
uniprot id: Q2YC94
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

323848:NMUL RS11745
gene id: 323848:NMUL_RS11745
uniprot id: Q2Y6S9
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

323848:NMUL RS02850
gene id: 323848:NMUL_RS02850
uniprot id: A0A1H5S069
uniprot id: Q2YBM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

323848:NMUL RS03500
gene id: 323848:NMUL_RS03500
uniprot id: A0A1H5SU65
uniprot id: Q2YBA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS13910
gene id: 323848:NMUL_RS13910
uniprot id: Q2Y5L5
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

323848:NMUL RS12095
gene id: 323848:NMUL_RS12095
uniprot id: Q2Y5C4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS10805
gene id: 323848:NMUL_RS10805
uniprot id: A0A1H5X3R9
uniprot id: Q2Y7A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

323848:NMUL RS12755
gene id: 323848:NMUL_RS12755
uniprot id: Q2Y688
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

323848:NMUL RS01610
gene id: 323848:NMUL_RS01610
uniprot id: Q2YCA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

323848:NMUL RS09775
gene id: 323848:NMUL_RS09775
uniprot id: Q2Y7W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

323848:NMUL RS11170
gene id: 323848:NMUL_RS11170
uniprot id: Q2Y737
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13500
gene id: 323848:NMUL_RS13500
uniprot id: Q2Y5U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

323848:NMUL RS11735
gene id: 323848:NMUL_RS11735
uniprot id: Q2Y6T1
names: Function
names: Similarity
messages: Belongs to the ClpA/ClpB family.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

323848:NMUL RS06885
gene id: 323848:NMUL_RS06885
uniprot id: Q2Y9G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

323848:NMUL RS02310
gene id: 323848:NMUL_RS02310
uniprot id: A0A1H5RRT0
uniprot id: Q2YBX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

323848:NMUL RS13650
gene id: 323848:NMUL_RS13650
uniprot id: A0A1H5WI06
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS04300
gene id: 323848:NMUL_RS04300
uniprot id: Q2YAV1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS02290
gene id: 323848:NMUL_RS02290
uniprot id: Q2YBX6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

323848:NMUL RS06270
gene id: 323848:NMUL_RS06270
uniprot id: Q2Y9S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

323848:NMUL RS06330
gene id: 323848:NMUL_RS06330
uniprot id: A0A1H5VML5
uniprot id: Q2Y9R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COX15/CtaA family. Type 2 subfamily.
messages: Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
messages: Cell membrane
messages: Interacts with CtaB.
messages: Membrane

323848:NMUL RS03190
gene id: 323848:NMUL_RS03190
uniprot id: A0A1H5XR74
uniprot id: Q2YBG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS06445
gene id: 323848:NMUL_RS06445
uniprot id: A0A1H5VQ94
uniprot id: Q2Y9P0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

323848:NMUL RS06470
gene id: 323848:NMUL_RS06470
uniprot id: Q2Y9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323848:NMUL RS05480
gene id: 323848:NMUL_RS05480
uniprot id: Q2YA77
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

323848:NMUL RS03760
gene id: 323848:NMUL_RS03760
uniprot id: Q2YB51
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

323848:NMUL RS09165
gene id: 323848:NMUL_RS09165
uniprot id: Q2Y876
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

323848:NMUL RS03690
gene id: 323848:NMUL_RS03690
uniprot id: Q2YB65
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

323848:NMUL RS13675
gene id: 323848:NMUL_RS13675
uniprot id: Q2Y5Q9
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

323848:NMUL RS10350
gene id: 323848:NMUL_RS10350
uniprot id: Q2Y7J9
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

323848:NMUL RS10775
gene id: 323848:NMUL_RS10775
uniprot id: A0A1H5X462
uniprot id: Q2Y7B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

323848:NMUL RS06175
gene id: 323848:NMUL_RS06175
uniprot id: Q2Y9U4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS11645
gene id: 323848:NMUL_RS11645
uniprot id: Q2Y6U7
names: Function
messages: Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.

323848:NMUL RS13835
gene id: 323848:NMUL_RS13835
uniprot id: Q2Y5M8
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

323848:NMUL RS04545
gene id: 323848:NMUL_RS04545
uniprot id: Q2YAR1
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323848:NMUL RS13530
gene id: 323848:NMUL_RS13530
uniprot id: Q2Y5T8
names: Similarity
messages: Belongs to the peptidase S24 family.

323848:NMUL RS04045
gene id: 323848:NMUL_RS04045
uniprot id: A0A1H5SZ64
uniprot id: Q2YB01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

323848:NMUL RS04105
gene id: 323848:NMUL_RS04105
uniprot id: Q2YAY9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

323848:NMUL RS00030
gene id: 323848:NMUL_RS00030
uniprot id: Q2YD56
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

323848:NMUL RS04775
gene id: 323848:NMUL_RS04775
uniprot id: Q2YAL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

323848:NMUL RS00050
gene id: 323848:NMUL_RS00050
uniprot id: Q2YD52
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

323848:NMUL RS12630
gene id: 323848:NMUL_RS12630
uniprot id: A0A1H5VSQ0
uniprot id: Q2Y6B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS13985
gene id: 323848:NMUL_RS13985
uniprot id: Q2Y5K0
names: Similarity
messages: Belongs to the CutA family.

323848:NMUL RS08690
gene id: 323848:NMUL_RS08690
uniprot id: A0A1H5WMJ5
uniprot id: Q2Y8G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

323848:NMUL RS05090
gene id: 323848:NMUL_RS05090
uniprot id: Q2YAF2
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS07710
gene id: 323848:NMUL_RS07710
uniprot id: Q2Y901
names: Similarity
messages: Belongs to the TPP enzyme family.

323848:NMUL RS03635
gene id: 323848:NMUL_RS03635
uniprot id: Q2YB75
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS05745
gene id: 323848:NMUL_RS05745
uniprot id: A0A1H5UJR7
uniprot id: Q2YA26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS00055
gene id: 323848:NMUL_RS00055
uniprot id: A0A1H5WPY8
uniprot id: Q2YD51
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

323848:NMUL RS00485
gene id: 323848:NMUL_RS00485
uniprot id: A0A1H5XEC5
uniprot id: Q2YCX0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

323848:NMUL RS08120
gene id: 323848:NMUL_RS08120
uniprot id: A0A1H5VX54
uniprot id: Q2Y8S0
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

323848:NMUL RS07055
gene id: 323848:NMUL_RS07055
uniprot id: Q2Y9C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

323848:NMUL RS05285
gene id: 323848:NMUL_RS05285
uniprot id: Q2YAB6
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

323848:NMUL RS07595
gene id: 323848:NMUL_RS07595
uniprot id: Q2Y923
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

323848:NMUL RS11440
gene id: 323848:NMUL_RS11440
uniprot id: A0A1H5WSR2
uniprot id: Q2Y6Y6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

323848:NMUL RS04235
gene id: 323848:NMUL_RS04235
uniprot id: Q2YAW3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

323848:NMUL RS01370
gene id: 323848:NMUL_RS01370
uniprot id: Q2YCF3
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

323848:NMUL RS12155
gene id: 323848:NMUL_RS12155
uniprot id: Q2Y6J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323848:NMUL RS11695
gene id: 323848:NMUL_RS11695
uniprot id: Q2Y6T8
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

323848:NMUL RS08975
gene id: 323848:NMUL_RS08975
uniprot id: Q2Y8B3
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS05890
gene id: 323848:NMUL_RS05890
uniprot id: A0A1H5ULG2
uniprot id: Q2Y9Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

323848:NMUL RS12060
gene id: 323848:NMUL_RS12060
uniprot id: Q2Y6L7
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

323848:NMUL RS04050
gene id: 323848:NMUL_RS04050
uniprot id: Q2YB00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

323848:NMUL RS09475
gene id: 323848:NMUL_RS09475
uniprot id: Q2Y815
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

323848:NMUL RS11875
gene id: 323848:NMUL_RS11875
uniprot id: Q2Y6Q4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS01630
gene id: 323848:NMUL_RS01630
uniprot id: A0A1H5RKV6
uniprot id: Q2YCA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

323848:NMUL RS00935
gene id: 323848:NMUL_RS00935
uniprot id: Q2YCN4
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

323848:NMUL RS01525
gene id: 323848:NMUL_RS01525
uniprot id: Q2YCC5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

323848:NMUL RS05125
gene id: 323848:NMUL_RS05125
uniprot id: A0A1H5SFJ4
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323848:NMUL RS13060
gene id: 323848:NMUL_RS13060
uniprot id: Q2Y627
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

323848:NMUL RS13075
gene id: 323848:NMUL_RS13075
uniprot id: A0A1H5TU39
uniprot id: Q2Y624
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

323848:NMUL RS02520
gene id: 323848:NMUL_RS02520
uniprot id: Q2YBT0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS00430
gene id: 323848:NMUL_RS00430
uniprot id: Q2YCY1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

323848:NMUL RS07075
gene id: 323848:NMUL_RS07075
uniprot id: Q2Y9C4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

323848:NMUL RS02085
gene id: 323848:NMUL_RS02085
uniprot id: Q2YC17
names: Similarity
messages: Belongs to the type IA topoisomerase family.

323848:NMUL RS13210
gene id: 323848:NMUL_RS13210
uniprot id: Q2Y5Z7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS01645
gene id: 323848:NMUL_RS01645
uniprot id: A0A1H5RKX3
uniprot id: Q2YCA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

323848:NMUL RS05865
gene id: 323848:NMUL_RS05865
uniprot id: A0A1H5UNI7
uniprot id: Q2YA02
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

323848:NMUL RS06305
gene id: 323848:NMUL_RS06305
uniprot id: A0A1H5VMD2
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

323848:NMUL RS03675
gene id: 323848:NMUL_RS03675
uniprot id: Q2YB68
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

323848:NMUL RS13175
gene id: 323848:NMUL_RS13175
uniprot id: Q2Y604
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS00975
gene id: 323848:NMUL_RS00975
uniprot id: Q2YCM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS06350
gene id: 323848:NMUL_RS06350
uniprot id: Q2Y9Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS04565
gene id: 323848:NMUL_RS04565
uniprot id: Q2YAQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS12140
gene id: 323848:NMUL_RS12140
uniprot id: Q2Y6K1
names: Similarity
messages: Belongs to the fructosamine kinase family.

323848:NMUL RS14320
gene id: 323848:NMUL_RS14320
uniprot id: A0A1H5USY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

323848:NMUL RS13590
gene id: 323848:NMUL_RS13590
uniprot id: Q2Y5S6
names: Similarity
messages: Belongs to the MT-A70-like family.

323848:NMUL RS13235
gene id: 323848:NMUL_RS13235
uniprot id: Q2Y5Z2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

323848:NMUL RS03895
gene id: 323848:NMUL_RS03895
uniprot id: Q2YB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323848:NMUL RS03815
gene id: 323848:NMUL_RS03815
uniprot id: Q2YB43
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

323848:NMUL RS05445
gene id: 323848:NMUL_RS05445
uniprot id: Q2YA84
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS06660
gene id: 323848:NMUL_RS06660
uniprot id: A0A1H5W5U0
uniprot id: Q2Y9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

323848:NMUL RS03885
gene id: 323848:NMUL_RS03885
uniprot id: Q2YB29
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323848:NMUL RS11415
gene id: 323848:NMUL_RS11415
uniprot id: A0A1H5WSS1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

323848:NMUL RS05255
gene id: 323848:NMUL_RS05255
uniprot id: Q2YAC0
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

323848:NMUL RS09205
gene id: 323848:NMUL_RS09205
uniprot id: A0A1H5V8W4
uniprot id: Q2Y867
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

323848:NMUL RS03520
gene id: 323848:NMUL_RS03520
uniprot id: Q2YB98
names: Similarity
messages: Belongs to the skp family.

323848:NMUL RS09235
gene id: 323848:NMUL_RS09235
uniprot id: Q2Y862
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323848:NMUL RS02465
gene id: 323848:NMUL_RS02465
uniprot id: A0A1H5RTH7
uniprot id: Q2YBU1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS02625
gene id: 323848:NMUL_RS02625
uniprot id: A0A1H5RXM3
uniprot id: Q2YBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS04070
gene id: 323848:NMUL_RS04070
uniprot id: A0A1H5SZA1
uniprot id: Q2YAZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

323848:NMUL RS00100
gene id: 323848:NMUL_RS00100
uniprot id: Q2YD42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

323848:NMUL RS02970
gene id: 323848:NMUL_RS02970
uniprot id: Q2YBK1
names: Similarity
messages: Belongs to the phosphoribulokinase family.

323848:NMUL RS03460
gene id: 323848:NMUL_RS03460
uniprot id: Q2YBA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ElaB/YgaM/YqjD family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS10875
gene id: 323848:NMUL_RS10875
uniprot id: A0A1H5X495
uniprot id: Q2Y796
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS07410
gene id: 323848:NMUL_RS07410
uniprot id: Q2Y960
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323848:NMUL RS01315
gene id: 323848:NMUL_RS01315
uniprot id: Q2YCG4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS14305
gene id: 323848:NMUL_RS14305
uniprot id: Q2Y5D6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS03470
gene id: 323848:NMUL_RS03470
uniprot id: Q2YBA7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

323848:NMUL RS10435
gene id: 323848:NMUL_RS10435
uniprot id: Q2Y7I1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

323848:NMUL RS06745
gene id: 323848:NMUL_RS06745
uniprot id: Q2Y9I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

323848:NMUL RS03680
gene id: 323848:NMUL_RS03680
uniprot id: Q2YB67
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

323848:NMUL RS11705
gene id: 323848:NMUL_RS11705
uniprot id: A0A1H5U5A7
uniprot id: Q2Y6T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS07125
gene id: 323848:NMUL_RS07125
uniprot id: Q2Y9B4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

323848:NMUL RS10000
gene id: 323848:NMUL_RS10000
uniprot id: Q2Y7R6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

323848:NMUL RS08505
gene id: 323848:NMUL_RS08505
uniprot id: A0A1H5WZB4
uniprot id: Q2Y8K1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

323848:NMUL RS05575
gene id: 323848:NMUL_RS05575
uniprot id: Q2YA58
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

323848:NMUL RS03355
gene id: 323848:NMUL_RS03355
uniprot id: Q2YBC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323848:NMUL RS07810
gene id: 323848:NMUL_RS07810
uniprot id: Q2Y8Y1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS14015
gene id: 323848:NMUL_RS14015
uniprot id: Q2Y5J4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

323848:NMUL RS04710
gene id: 323848:NMUL_RS04710
uniprot id: Q2YAM7
names: Similarity
messages: Belongs to the GST superfamily.

323848:NMUL RS05470
gene id: 323848:NMUL_RS05470
uniprot id: Q2YA79
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS02680
gene id: 323848:NMUL_RS02680
uniprot id: Q2YBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

323848:NMUL RS03370
gene id: 323848:NMUL_RS03370
uniprot id: Q2YBC6
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS08325
gene id: 323848:NMUL_RS08325
uniprot id: Q2Y8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS11155
gene id: 323848:NMUL_RS11155
uniprot id: A0A1H5VIB4
uniprot id: Q2Y740
names: Similarity
messages: Belongs to the UPF0758 family.

323848:NMUL RS00350
gene id: 323848:NMUL_RS00350
uniprot id: A0A1H5Y0T4
uniprot id: Q2YCZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

323848:NMUL RS02695
gene id: 323848:NMUL_RS02695
uniprot id: Q2YBQ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TtcA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.
messages: Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
messages: Cytoplasm
messages: Homodimer.
messages: The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.

323848:NMUL RS11100
gene id: 323848:NMUL_RS11100
uniprot id: A0A1H5VJQ3
uniprot id: Q2Y751
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

323848:NMUL RS09725
gene id: 323848:NMUL_RS09725
uniprot id: Q2Y7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

323848:NMUL RS08080
gene id: 323848:NMUL_RS08080
uniprot id: A0A1H5VYN7
uniprot id: Q2Y8S8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

323848:NMUL RS05515
gene id: 323848:NMUL_RS05515
uniprot id: Q2YA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323848:NMUL RS13095
gene id: 323848:NMUL_RS13095
uniprot id: A0A1H5TTW2
names: Cofactor
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

323848:NMUL RS04215
gene id: 323848:NMUL_RS04215
uniprot id: Q2YAW7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

323848:NMUL RS10980
gene id: 323848:NMUL_RS10980
uniprot id: Q2Y775
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS06965
gene id: 323848:NMUL_RS06965
uniprot id: Q2Y9E6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323848:NMUL RS09695
gene id: 323848:NMUL_RS09695
uniprot id: A0A1H5TGN0
uniprot id: Q2Y7X4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

323848:NMUL RS02020
gene id: 323848:NMUL_RS02020
uniprot id: Q2YC29
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

323848:NMUL RS13615
gene id: 323848:NMUL_RS13615
uniprot id: Q2Y5S1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13690
gene id: 323848:NMUL_RS13690
uniprot id: Q2Y5Q6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

323848:NMUL RS07000
gene id: 323848:NMUL_RS07000
uniprot id: Q2Y9D9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

323848:NMUL RS01780
gene id: 323848:NMUL_RS01780
uniprot id: A0A1H5RLS4
names: Subcellular Location Annotation
messages: Mitochondrion

323848:NMUL RS09965
gene id: 323848:NMUL_RS09965
uniprot id: Q2Y7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

323848:NMUL RS01605
gene id: 323848:NMUL_RS01605
uniprot id: Q2YCB0
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS02455
gene id: 323848:NMUL_RS02455
uniprot id: Q2YBU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

323848:NMUL RS10200
gene id: 323848:NMUL_RS10200
uniprot id: Q2Y7M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

323848:NMUL RS02730
gene id: 323848:NMUL_RS02730
uniprot id: Q2YBP7
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13635
gene id: 323848:NMUL_RS13635
uniprot id: Q2Y5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

323848:NMUL RS06520
gene id: 323848:NMUL_RS06520
uniprot id: A0A1H5VPR5
uniprot id: Q2Y9M6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

323848:NMUL RS06140
gene id: 323848:NMUL_RS06140
uniprot id: Q2Y9V1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323848:NMUL RS13970
gene id: 323848:NMUL_RS13970
uniprot id: Q2Y5K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS02740
gene id: 323848:NMUL_RS02740
uniprot id: A0A1H5RZ86
uniprot id: Q2YBP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

323848:NMUL RS12200
gene id: 323848:NMUL_RS12200
uniprot id: A0A1H5XHB1
uniprot id: Q2Y6J1
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

323848:NMUL RS13030
gene id: 323848:NMUL_RS13030
uniprot id: A0A1H5TUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

323848:NMUL RS03670
gene id: 323848:NMUL_RS03670
uniprot id: Q2YB69
names: Similarity
messages: Belongs to the HesB/IscA family.

323848:NMUL RS03130
gene id: 323848:NMUL_RS03130
uniprot id: Q2YBH1
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

323848:NMUL RS03475
gene id: 323848:NMUL_RS03475
uniprot id: A0A1H5SS98
uniprot id: Q2YBA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

323848:NMUL RS09550
gene id: 323848:NMUL_RS09550
uniprot id: Q2Y801
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS11620
gene id: 323848:NMUL_RS11620
uniprot id: Q2Y6V2
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

323848:NMUL RS06255
gene id: 323848:NMUL_RS06255
uniprot id: Q2Y9S9
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

323848:NMUL RS04020
gene id: 323848:NMUL_RS04020
uniprot id: A0A1H5SYK7
uniprot id: Q2YB06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

323848:NMUL RS02375
gene id: 323848:NMUL_RS02375
uniprot id: Q2YBV9
names: Similarity
messages: Belongs to the SCO1/2 family.

323848:NMUL RS06750
gene id: 323848:NMUL_RS06750
uniprot id: Q2Y9I6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323848:NMUL RS14275
gene id: 323848:NMUL_RS14275
uniprot id: Q2Y5E2
names: Similarity
messages: Belongs to the BolA/IbaG family.

323848:NMUL RS02515
gene id: 323848:NMUL_RS02515
uniprot id: Q2YBT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

323848:NMUL RS03380
gene id: 323848:NMUL_RS03380
uniprot id: Q2YBC4
names: Similarity
messages: Belongs to the RecJ family.

323848:NMUL RS14265
gene id: 323848:NMUL_RS14265
uniprot id: Q2Y5E4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

323848:NMUL RS12650
gene id: 323848:NMUL_RS12650
uniprot id: Q2Y6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

323848:NMUL RS05850
gene id: 323848:NMUL_RS05850
uniprot id: Q2YA06
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS08610
gene id: 323848:NMUL_RS08610
uniprot id: Q2Y8I1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS11120
gene id: 323848:NMUL_RS11120
uniprot id: Q2Y747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

323848:NMUL RS02065
gene id: 323848:NMUL_RS02065
uniprot id: A0A1H5RP76
uniprot id: Q2YC20
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

323848:NMUL RS00200
gene id: 323848:NMUL_RS00200
uniprot id: Q2YD23
names: Similarity
messages: Belongs to the type IB topoisomerase family.

323848:NMUL RS03485
gene id: 323848:NMUL_RS03485
uniprot id: A0A1H5SS79
uniprot id: Q2YBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

323848:NMUL RS12270
gene id: 323848:NMUL_RS12270
uniprot id: Q2Y6H8
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS04055
gene id: 323848:NMUL_RS04055
uniprot id: A0A1H5SZ96
uniprot id: Q2YAZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

323848:NMUL RS01130
gene id: 323848:NMUL_RS01130
uniprot id: Q2YCJ6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

323848:NMUL RS06915
gene id: 323848:NMUL_RS06915
uniprot id: Q2Y9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

323848:NMUL RS02380
gene id: 323848:NMUL_RS02380
uniprot id: Q2YBV8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

323848:NMUL RS05165
gene id: 323848:NMUL_RS05165
uniprot id: Q2YAD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323848:NMUL RS05460
gene id: 323848:NMUL_RS05460
uniprot id: A0A1H5SKV4
uniprot id: Q2YA81
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

323848:NMUL RS12400
gene id: 323848:NMUL_RS12400
uniprot id: A0A1H5W2L1
uniprot id: Q2Y6F2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

323848:NMUL RS02125
gene id: 323848:NMUL_RS02125
uniprot id: Q2YC09
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

323848:NMUL RS03060
gene id: 323848:NMUL_RS03060
uniprot id: Q2YBI4
names: Similarity
messages: Belongs to the UPF0235 family.

323848:NMUL RS09280
gene id: 323848:NMUL_RS09280
uniprot id: Q2Y854
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS12935
gene id: 323848:NMUL_RS12935
uniprot id: A0A1H5TWC2
uniprot id: Q2Y653
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

323848:NMUL RS15380
gene id: 323848:NMUL_RS15380
uniprot id: Q2Y8E8
names: Similarity
messages: Belongs to the peptidase A31 family.

323848:NMUL RS12910
gene id: 323848:NMUL_RS12910
uniprot id: Q2Y658
names: Similarity
messages: Belongs to the universal stress protein A family.

323848:NMUL RS06035
gene id: 323848:NMUL_RS06035
uniprot id: A0A1H5UN57
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

323848:NMUL RS02905
gene id: 323848:NMUL_RS02905
uniprot id: Q2YBL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

323848:NMUL RS04010
gene id: 323848:NMUL_RS04010
uniprot id: A0A1H5SYG5
uniprot id: Q2YB08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

323848:NMUL RS01405
gene id: 323848:NMUL_RS01405
uniprot id: Q2YCE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

323848:NMUL RS11020
gene id: 323848:NMUL_RS11020
uniprot id: A0A1H5VIH8
uniprot id: Q2Y767
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

323848:NMUL RS08185
gene id: 323848:NMUL_RS08185
uniprot id: Q2Y8Q7
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

323848:NMUL RS01400
gene id: 323848:NMUL_RS01400
uniprot id: Q2YCE9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

323848:NMUL RS02345
gene id: 323848:NMUL_RS02345
uniprot id: Q2YBW5
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

323848:NMUL RS04540
gene id: 323848:NMUL_RS04540
uniprot id: Q2YAR2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323848:NMUL RS02075
gene id: 323848:NMUL_RS02075
uniprot id: Q2YC18
names: Similarity
messages: Belongs to the DprA/Smf family.

323848:NMUL RS13050
gene id: 323848:NMUL_RS13050
uniprot id: A0A1H5TW76
uniprot id: Q2Y630
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

323848:NMUL RS10015
gene id: 323848:NMUL_RS10015
uniprot id: A0A1H5TCE8
uniprot id: Q2Y7R3
names: Similarity
messages: Belongs to the TrpF family.

323848:NMUL RS00020
gene id: 323848:NMUL_RS00020
uniprot id: A0A1H5WPL7
uniprot id: Q2YD58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS01895
gene id: 323848:NMUL_RS01895
uniprot id: Q2YC54
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

323848:NMUL RS12310
gene id: 323848:NMUL_RS12310
uniprot id: Q2Y6H0
names: Similarity
messages: Belongs to the bacterial secretin family.

323848:NMUL RS10890
gene id: 323848:NMUL_RS10890
uniprot id: Q2Y793
names: Similarity
messages: Belongs to the thioredoxin family.

323848:NMUL RS11425
gene id: 323848:NMUL_RS11425
uniprot id: Q2Y6Y8
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

323848:NMUL RS06970
gene id: 323848:NMUL_RS06970
uniprot id: Q2Y9E5
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

323848:NMUL RS07140
gene id: 323848:NMUL_RS07140
uniprot id: Q2Y9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

323848:NMUL RS10945
gene id: 323848:NMUL_RS10945
uniprot id: Q2Y783
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

323848:NMUL RS03420
gene id: 323848:NMUL_RS03420
uniprot id: Q2YBB6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

323848:NMUL RS04150
gene id: 323848:NMUL_RS04150
uniprot id: A0A1H5T0J2
uniprot id: Q2YAY0
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

323848:NMUL RS13905
gene id: 323848:NMUL_RS13905
uniprot id: Q2Y5L6
names: Similarity
messages: Belongs to the asparagine synthetase family.

323848:NMUL RS12595
gene id: 323848:NMUL_RS12595
uniprot id: Q2Y6B7
names: Similarity
messages: Belongs to the peptidase U62 family.

323848:NMUL RS12775
gene id: 323848:NMUL_RS12775
uniprot id: Q2Y685
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

323848:NMUL RS03595
gene id: 323848:NMUL_RS03595
uniprot id: A0A1H5SVE3
uniprot id: Q2YB83
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

323848:NMUL RS15530
gene id: 323848:NMUL_RS15530
uniprot id: Q2Y5A5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

323848:NMUL RS10430
gene id: 323848:NMUL_RS10430
uniprot id: Q2Y7I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS04130
gene id: 323848:NMUL_RS04130
uniprot id: A0A1H5T1U6
uniprot id: Q2YAY4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

323848:NMUL RS01580
gene id: 323848:NMUL_RS01580
uniprot id: Q2YCB4
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

323848:NMUL RS05625
gene id: 323848:NMUL_RS05625
uniprot id: A0A1H5SKJ9
uniprot id: Q2YA48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

323848:NMUL RS10260
gene id: 323848:NMUL_RS10260
uniprot id: Q2Y7L5
names: Similarity
messages: Belongs to the peptidase M17 family.

323848:NMUL RS01045
gene id: 323848:NMUL_RS01045
uniprot id: Q2YCL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell inner membrane
messages: Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter.

323848:NMUL RS13055
gene id: 323848:NMUL_RS13055
uniprot id: A0A1H5TUH9
uniprot id: Q2Y629
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

323848:NMUL RS05785
gene id: 323848:NMUL_RS05785
uniprot id: Q2YA18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS07050
gene id: 323848:NMUL_RS07050
uniprot id: Q2Y9C9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

323848:NMUL RS11430
gene id: 323848:NMUL_RS11430
uniprot id: Q2Y6Y7
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

323848:NMUL RS06960
gene id: 323848:NMUL_RS06960
uniprot id: Q2Y9E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

323848:NMUL RS10755
gene id: 323848:NMUL_RS10755
uniprot id: Q2Y7B9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

323848:NMUL RS02095
gene id: 323848:NMUL_RS02095
uniprot id: Q2YC15
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

323848:NMUL RS04675
gene id: 323848:NMUL_RS04675
uniprot id: Q2YAN4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

323848:NMUL RS00060
gene id: 323848:NMUL_RS00060
uniprot id: A0A1H5WPZ1
uniprot id: Q2YD50
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

323848:NMUL RS06440
gene id: 323848:NMUL_RS06440
uniprot id: A0A1H5VR38
uniprot id: Q2Y9P1
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS13285
gene id: 323848:NMUL_RS13285
uniprot id: A0A1H5TR68
uniprot id: Q2Y5Y2
names: Similarity
messages: Belongs to the UPF0276 family.

323848:NMUL RS00895
gene id: 323848:NMUL_RS00895
uniprot id: Q2YCP2
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

323848:NMUL RS05210
gene id: 323848:NMUL_RS05210
uniprot id: Q2YAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

323848:NMUL RS10125
gene id: 323848:NMUL_RS10125
uniprot id: A0A1H5TCQ9
uniprot id: Q2Y7P0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

323848:NMUL RS02940
gene id: 323848:NMUL_RS02940
uniprot id: A0A1H5WFY7
uniprot id: Q2YBK7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

323848:NMUL RS10825
gene id: 323848:NMUL_RS10825
uniprot id: Q2Y7A5
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

323848:NMUL RS08705
gene id: 323848:NMUL_RS08705
uniprot id: Q2Y8G3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

323848:NMUL RS14105
gene id: 323848:NMUL_RS14105
uniprot id: A0A1H5UWV6
uniprot id: Q2Y5H5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

323848:NMUL RS10895
gene id: 323848:NMUL_RS10895
uniprot id: Q2Y792
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS12135
gene id: 323848:NMUL_RS12135
uniprot id: A0A1H5XHV6
uniprot id: Q2Y6K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

323848:NMUL RS11685
gene id: 323848:NMUL_RS11685
uniprot id: A0A1H5U7W5
uniprot id: Q2Y6U0
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

323848:NMUL RS02275
gene id: 323848:NMUL_RS02275
uniprot id: Q2YBX9
names: Similarity
messages: Belongs to the GppA/Ppx family.

323848:NMUL RS08730
gene id: 323848:NMUL_RS08730
uniprot id: Q2Y8F9
names: Similarity
messages: Belongs to the HupF/HypC family.

323848:NMUL RS07215
gene id: 323848:NMUL_RS07215
uniprot id: Q2Y996
names: Similarity
messages: Belongs to the Gfa family.

323848:NMUL RS09630
gene id: 323848:NMUL_RS09630
uniprot id: Q2Y7Y7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323848:NMUL RS14040
gene id: 323848:NMUL_RS14040
uniprot id: A0A1H5UVW9
names: Similarity
messages: Belongs to the PhoH family.

323848:NMUL RS04930
gene id: 323848:NMUL_RS04930
uniprot id: A0A1H5SD27
uniprot id: Q2YAI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS05005
gene id: 323848:NMUL_RS05005
uniprot id: Q2YAG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

323848:NMUL RS13215
gene id: 323848:NMUL_RS13215
uniprot id: Q2Y5Z6
names: Similarity
messages: Belongs to the P(II) protein family.

323848:NMUL RS08295
gene id: 323848:NMUL_RS08295
uniprot id: Q2Y8N8
names: Similarity
messages: Belongs to the peptidase S33 family.

323848:NMUL RS00920
gene id: 323848:NMUL_RS00920
uniprot id: Q2YCN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

323848:NMUL RS11990
gene id: 323848:NMUL_RS11990
uniprot id: Q2Y6N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323848:NMUL RS02435
gene id: 323848:NMUL_RS02435
uniprot id: Q2YBU7
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS05600
gene id: 323848:NMUL_RS05600
uniprot id: Q2YA53
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

323848:NMUL RS13680
gene id: 323848:NMUL_RS13680
uniprot id: Q2Y5Q8
names: Similarity
messages: Belongs to the rubredoxin family.

323848:NMUL RS12635
gene id: 323848:NMUL_RS12635
uniprot id: A0A1H5VSS0
uniprot id: Q2Y6A9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

323848:NMUL RS05400
gene id: 323848:NMUL_RS05400
uniprot id: A0A1H5SIZ1
uniprot id: Q2YA93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS04790
gene id: 323848:NMUL_RS04790
uniprot id: Q2YAL1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

323848:NMUL RS01835
gene id: 323848:NMUL_RS01835
uniprot id: A0A1H5RNX2
uniprot id: Q2YC65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

323848:NMUL RS11165
gene id: 323848:NMUL_RS11165
uniprot id: A0A1H5VGY4
uniprot id: Q2Y738
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

323848:NMUL RS00130
gene id: 323848:NMUL_RS00130
uniprot id: Q2YD36
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS05440
gene id: 323848:NMUL_RS05440
uniprot id: A0A1H5SJ43
uniprot id: Q2YA85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

323848:NMUL RS02860
gene id: 323848:NMUL_RS02860
uniprot id: Q2YBM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS08710
gene id: 323848:NMUL_RS08710
uniprot id: A0A1H5WMC9
uniprot id: Q2Y8G2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

323848:NMUL RS01545
gene id: 323848:NMUL_RS01545
uniprot id: Q2YCC1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS06930
gene id: 323848:NMUL_RS06930
uniprot id: Q2Y9F3
names: Similarity
messages: Belongs to the MotB family.

323848:NMUL RS06680
gene id: 323848:NMUL_RS06680
uniprot id: Q2Y9J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

323848:NMUL RS07405
gene id: 323848:NMUL_RS07405
uniprot id: Q2Y961
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS04185
gene id: 323848:NMUL_RS04185
uniprot id: A0A1H5T0I9
uniprot id: Q2YAX3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

323848:NMUL RS11305
gene id: 323848:NMUL_RS11305
uniprot id: Q2Y711
names: Similarity
messages: Belongs to the cytochrome P450 family.

323848:NMUL RS09910
gene id: 323848:NMUL_RS09910
uniprot id: Q2Y7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS13620
gene id: 323848:NMUL_RS13620
uniprot id: Q2Y5S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

323848:NMUL RS14510
gene id: 323848:NMUL_RS14510
uniprot id: Q2Y599
names: Similarity
messages: Belongs to the RelE toxin family.

323848:NMUL RS07520
gene id: 323848:NMUL_RS07520
uniprot id: Q2Y939
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13240
gene id: 323848:NMUL_RS13240
uniprot id: A0A1H5TTX4
uniprot id: Q2Y5Z1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

323848:NMUL RS08680
gene id: 323848:NMUL_RS08680
uniprot id: A0A1H5WLS7
uniprot id: Q2Y8G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

323848:NMUL RS13245
gene id: 323848:NMUL_RS13245
uniprot id: A0A1H5TRR5
uniprot id: Q2Y5Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS10795
gene id: 323848:NMUL_RS10795
uniprot id: A0A1H5X3S8
uniprot id: Q2Y7B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

323848:NMUL RS11845
gene id: 323848:NMUL_RS11845
uniprot id: A0A1H5U3X4
uniprot id: Q2Y6R0
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

323848:NMUL RS12990
gene id: 323848:NMUL_RS12990
uniprot id: A0A1H5TVC6
uniprot id: Q2Y642
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323848:NMUL RS02450
gene id: 323848:NMUL_RS02450
uniprot id: A0A1H5RTK1
uniprot id: Q2YBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

323848:NMUL RS13015
gene id: 323848:NMUL_RS13015
uniprot id: Q2Y637
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

323848:NMUL RS03625
gene id: 323848:NMUL_RS03625
uniprot id: Q2YB77
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323848:NMUL RS07160
gene id: 323848:NMUL_RS07160
uniprot id: Q2Y9A7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

323848:NMUL RS09870
gene id: 323848:NMUL_RS09870
uniprot id: Q2Y7U2
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

323848:NMUL RS02570
gene id: 323848:NMUL_RS02570
uniprot id: A0A1H5RXC0
uniprot id: Q2YBS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

323848:NMUL RS01310
gene id: 323848:NMUL_RS01310
uniprot id: Q2YCG5
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03125
gene id: 323848:NMUL_RS03125
uniprot id: A0A1H5WE17
uniprot id: Q2YBH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

323848:NMUL RS09690
gene id: 323848:NMUL_RS09690
uniprot id: A0A1H5TGV7
uniprot id: Q2Y7X5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

323848:NMUL RS02915
gene id: 323848:NMUL_RS02915
uniprot id: A0A1H5WGJ5
uniprot id: Q2YBL2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323848:NMUL RS10955
gene id: 323848:NMUL_RS10955
uniprot id: Q2Y781
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

323848:NMUL RS05670
gene id: 323848:NMUL_RS05670
uniprot id: Q2YA39
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

323848:NMUL RS03360
gene id: 323848:NMUL_RS03360
uniprot id: Q2YBC8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

323848:NMUL RS12195
gene id: 323848:NMUL_RS12195
uniprot id: Q2Y6J2
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

323848:NMUL RS02955
gene id: 323848:NMUL_RS02955
uniprot id: A0A1H5WFP5
uniprot id: Q2YBK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

323848:NMUL RS12995
gene id: 323848:NMUL_RS12995
uniprot id: A0A1H5TXF2
uniprot id: Q2Y641
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

323848:NMUL RS05380
gene id: 323848:NMUL_RS05380
uniprot id: Q2YA97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS11090
gene id: 323848:NMUL_RS11090
uniprot id: Q2Y753
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

323848:NMUL RS09605
gene id: 323848:NMUL_RS09605
uniprot id: Q2Y7Z0
names: Similarity
messages: Belongs to the thioesterase family.

323848:NMUL RS07135
gene id: 323848:NMUL_RS07135
uniprot id: Q2Y9B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

323848:NMUL RS11075
gene id: 323848:NMUL_RS11075
uniprot id: Q2Y756
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS07260
gene id: 323848:NMUL_RS07260
uniprot id: Q2Y987
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

323848:NMUL RS11015
gene id: 323848:NMUL_RS11015
uniprot id: Q2Y768
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

323848:NMUL RS04195
gene id: 323848:NMUL_RS04195
uniprot id: A0A1H5T125
uniprot id: Q2YAX1
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

323848:NMUL RS06515
gene id: 323848:NMUL_RS06515
uniprot id: A0A1H5VPX8
uniprot id: Q2Y9M7
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

323848:NMUL RS00930
gene id: 323848:NMUL_RS00930
uniprot id: A0A1H5Y6Y4
uniprot id: Q2YCN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

323848:NMUL RS02385
gene id: 323848:NMUL_RS02385
uniprot id: Q2YBV7
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

323848:NMUL RS02565
gene id: 323848:NMUL_RS02565
uniprot id: A0A1H5RUZ2
uniprot id: Q2YBS1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323848:NMUL RS13850
gene id: 323848:NMUL_RS13850
uniprot id: Q2YA33
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

323848:NMUL RS12055
gene id: 323848:NMUL_RS12055
uniprot id: Q2Y6L8
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

323848:NMUL RS00695
gene id: 323848:NMUL_RS00695
uniprot id: Q2YCS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

323848:NMUL RS10815
gene id: 323848:NMUL_RS10815
uniprot id: Q2Y7A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

323848:NMUL RS08400
gene id: 323848:NMUL_RS08400
uniprot id: Q2Y8L8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

323848:NMUL RS06505
gene id: 323848:NMUL_RS06505
uniprot id: A0A1H5VPZ3
uniprot id: Q2Y9M9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

323848:NMUL RS06155
gene id: 323848:NMUL_RS06155
uniprot id: Q2Y9U8
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323848:NMUL RS06905
gene id: 323848:NMUL_RS06905
uniprot id: Q2Y9F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

323848:NMUL RS02005
gene id: 323848:NMUL_RS02005
uniprot id: A0A1H5RNS6
uniprot id: Q2YC32
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

323848:NMUL RS05765
gene id: 323848:NMUL_RS05765
uniprot id: Q2YA22
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

323848:NMUL RS12365
gene id: 323848:NMUL_RS12365
uniprot id: A0A1H5W1B2
uniprot id: Q2Y6F9
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

323848:NMUL RS09195
gene id: 323848:NMUL_RS09195
uniprot id: Q2Y870
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS09480
gene id: 323848:NMUL_RS09480
uniprot id: A0A1H5WAT7
uniprot id: Q2Y814
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

323848:NMUL RS00005
gene id: 323848:NMUL_RS00005
uniprot id: Q2YD61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

323848:NMUL RS04650
gene id: 323848:NMUL_RS04650
uniprot id: A0A1H5S8N9
uniprot id: Q2YAN9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

323848:NMUL RS08130
gene id: 323848:NMUL_RS08130
uniprot id: Q2Y8R8
names: Similarity
messages: Belongs to the threonine synthase family.

323848:NMUL RS06795
gene id: 323848:NMUL_RS06795
uniprot id: Q2Y9H7
names: Subcellular Location Annotation
messages: Cytoplasm

323848:NMUL RS10340
gene id: 323848:NMUL_RS10340
uniprot id: Q2Y7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323848:NMUL RS07040
gene id: 323848:NMUL_RS07040
uniprot id: Q2Y9D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

323848:NMUL RS11885
gene id: 323848:NMUL_RS11885
uniprot id: Q2Y6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

323848:NMUL RS12945
gene id: 323848:NMUL_RS12945
uniprot id: A0A1H5TVS8
uniprot id: Q2Y651
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

323848:NMUL RS08745
gene id: 323848:NMUL_RS08745
uniprot id: Q2Y8F6
names: Similarity
messages: Belongs to the HypD family.

323848:NMUL RS13035
gene id: 323848:NMUL_RS13035
uniprot id: Q2Y633
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS01365
gene id: 323848:NMUL_RS01365
uniprot id: Q2YCF4
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

323848:NMUL RS07390
gene id: 323848:NMUL_RS07390
uniprot id: Q2Y964
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

323848:NMUL RS14665
gene id: 323848:NMUL_RS14665
uniprot id: Q2Y571
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

323848:NMUL RS11715
gene id: 323848:NMUL_RS11715
uniprot id: Q2Y6T4
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

323848:NMUL RS14160
gene id: 323848:NMUL_RS14160
uniprot id: A0A1H5UUW3
uniprot id: Q2Y5G4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

323848:NMUL RS01140
gene id: 323848:NMUL_RS01140
uniprot id: Q2YCJ4
names: Subcellular Location Annotation
messages: Cytoplasm

323848:NMUL RS11325
gene id: 323848:NMUL_RS11325
uniprot id: Q2Y708
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

323848:NMUL RS05385
gene id: 323848:NMUL_RS05385
uniprot id: A0A1H5SI00
uniprot id: Q2YA96
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS04870
gene id: 323848:NMUL_RS04870
uniprot id: Q2YAJ5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS04340
gene id: 323848:NMUL_RS04340
uniprot id: A0A1H5XSQ4
uniprot id: Q2YAU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

323848:NMUL RS14255
gene id: 323848:NMUL_RS14255
uniprot id: Q2Y5E6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

323848:NMUL RS11725
gene id: 323848:NMUL_RS11725
uniprot id: Q2Y6T3
names: Subcellular Location Annotation
messages: Cytoplasm

323848:NMUL RS14095
gene id: 323848:NMUL_RS14095
uniprot id: Q2Y5H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

323848:NMUL RS05230
gene id: 323848:NMUL_RS05230
uniprot id: A0A1H5SII8
uniprot id: Q2YAC5
names: Similarity
messages: Belongs to the XFP family.

323848:NMUL RS01960
gene id: 323848:NMUL_RS01960
uniprot id: Q2YC41
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

323848:NMUL RS06355
gene id: 323848:NMUL_RS06355
uniprot id: A0A1H5VMY7
uniprot id: Q2Y9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

323848:NMUL RS04725
gene id: 323848:NMUL_RS04725
uniprot id: Q2YAM4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS01690
gene id: 323848:NMUL_RS01690
uniprot id: Q2YC93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

323848:NMUL RS04330
gene id: 323848:NMUL_RS04330
uniprot id: A0A1H5XSI6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

323848:NMUL RS08065
gene id: 323848:NMUL_RS08065
uniprot id: A0A1H5VX97
uniprot id: Q2Y8T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

323848:NMUL RS06375
gene id: 323848:NMUL_RS06375
uniprot id: Q2Y9Q4
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

323848:NMUL RS05545
gene id: 323848:NMUL_RS05545
uniprot id: Q2YA64
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03615
gene id: 323848:NMUL_RS03615
uniprot id: Q2YB79
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

323848:NMUL RS13715
gene id: 323848:NMUL_RS13715
uniprot id: A0A1H5WJ57
uniprot id: Q2Y5Q1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

323848:NMUL RS11995
gene id: 323848:NMUL_RS11995
uniprot id: Q2Y6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323848:NMUL RS14060
gene id: 323848:NMUL_RS14060
uniprot id: Q2Y5I4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

323848:NMUL RS13325
gene id: 323848:NMUL_RS13325
uniprot id: Q2Y5X4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS09935
gene id: 323848:NMUL_RS09935
uniprot id: Q2Y7S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS10820
gene id: 323848:NMUL_RS10820
uniprot id: A0A1H5X3J0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

323848:NMUL RS03775
gene id: 323848:NMUL_RS03775
uniprot id: A0A1H5SVJ2
uniprot id: Q2YB48
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

323848:NMUL RS03755
gene id: 323848:NMUL_RS03755
uniprot id: A0A1H5SVQ4
uniprot id: Q2YB52
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

323848:NMUL RS11590
gene id: 323848:NMUL_RS11590
uniprot id: Q2Y6V8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

323848:NMUL RS03645
gene id: 323848:NMUL_RS03645
uniprot id: Q2YB73
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS05900
gene id: 323848:NMUL_RS05900
uniprot id: Q2Y9Z5
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

323848:NMUL RS05475
gene id: 323848:NMUL_RS05475
uniprot id: A0A1H5SLK1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

323848:NMUL RS01900
gene id: 323848:NMUL_RS01900
uniprot id: Q2YC53
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

323848:NMUL RS03705
gene id: 323848:NMUL_RS03705
uniprot id: Q2YB62
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323848:NMUL RS12415
gene id: 323848:NMUL_RS12415
uniprot id: A0A1H5W2J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

323848:NMUL RS02340
gene id: 323848:NMUL_RS02340
uniprot id: A0A1H5RS97
uniprot id: Q2YBW6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

323848:NMUL RS14130
gene id: 323848:NMUL_RS14130
uniprot id: A0A1H5UUU4
uniprot id: Q2Y5H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323848:NMUL RS08515
gene id: 323848:NMUL_RS08515
uniprot id: Q2Y8J9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

323848:NMUL RS04445
gene id: 323848:NMUL_RS04445
uniprot id: Q2YAS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

323848:NMUL RS02025
gene id: 323848:NMUL_RS02025
uniprot id: Q2YC28
names: Similarity
messages: Belongs to the pyruvate kinase family.

323848:NMUL RS05920
gene id: 323848:NMUL_RS05920
uniprot id: Q2Y9Z1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

323848:NMUL RS02745
gene id: 323848:NMUL_RS02745
uniprot id: Q2YBP4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

323848:NMUL RS08800
gene id: 323848:NMUL_RS08800
uniprot id: Q2Y8E5
names: Similarity
messages: Belongs to the universal stress protein A family.

323848:NMUL RS08300
gene id: 323848:NMUL_RS08300
uniprot id: Q2Y8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

323848:NMUL RS08330
gene id: 323848:NMUL_RS08330
uniprot id: Q2Y8N1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS02610
gene id: 323848:NMUL_RS02610
uniprot id: Q2YBR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

323848:NMUL RS07290
gene id: 323848:NMUL_RS07290
uniprot id: A0A1H5UEB9
uniprot id: Q2Y981
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

323848:NMUL RS01885
gene id: 323848:NMUL_RS01885
uniprot id: A0A1H5RMG3
uniprot id: Q2YC56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

323848:NMUL RS14020
gene id: 323848:NMUL_RS14020
uniprot id: Q2Y5J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

323848:NMUL RS09980
gene id: 323848:NMUL_RS09980
uniprot id: Q2Y7S0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS00015
gene id: 323848:NMUL_RS00015
uniprot id: Q2YD59
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

323848:NMUL RS11160
gene id: 323848:NMUL_RS11160
uniprot id: A0A1H5VGP4
uniprot id: Q2Y739
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

323848:NMUL RS05220
gene id: 323848:NMUL_RS05220
uniprot id: Q2YAC7
names: Similarity
messages: Belongs to the universal stress protein A family.

323848:NMUL RS08090
gene id: 323848:NMUL_RS08090
uniprot id: Q2Y8S6
names: Similarity
messages: Belongs to the glutamate synthase family.

323848:NMUL RS04700
gene id: 323848:NMUL_RS04700
uniprot id: Q2YAM9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

323848:NMUL RS10005
gene id: 323848:NMUL_RS10005
uniprot id: A0A1H5TCN6
uniprot id: Q2Y7R5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

323848:NMUL RS14090
gene id: 323848:NMUL_RS14090
uniprot id: Q2Y5H8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

323848:NMUL RS01240
gene id: 323848:NMUL_RS01240
uniprot id: Q2YCH6
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

323848:NMUL RS12965
gene id: 323848:NMUL_RS12965
uniprot id: A0A1H5TXV5
uniprot id: Q2Y647
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

323848:NMUL RS11065
gene id: 323848:NMUL_RS11065
uniprot id: Q2Y758
names: Similarity
messages: Belongs to the OprB family.

323848:NMUL RS01020
gene id: 323848:NMUL_RS01020
uniprot id: Q2YCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

323848:NMUL RS12615
gene id: 323848:NMUL_RS12615
uniprot id: A0A1H5VTF0
uniprot id: Q2Y6B3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

323848:NMUL RS12810
gene id: 323848:NMUL_RS12810
uniprot id: Q2Y678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

323848:NMUL RS06880
gene id: 323848:NMUL_RS06880
uniprot id: Q2Y9G2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

323848:NMUL RS06280
gene id: 323848:NMUL_RS06280
uniprot id: Q2Y9S4
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

323848:NMUL RS05935
gene id: 323848:NMUL_RS05935
uniprot id: A0A1H5UM14
uniprot id: Q2Y9Y8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

323848:NMUL RS05650
gene id: 323848:NMUL_RS05650
uniprot id: Q2YA43
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

323848:NMUL RS15100
gene id: 323848:NMUL_RS15100
uniprot id: Q2Y565
names: Similarity
messages: Belongs to the MobA/MobL family.

323848:NMUL RS10995
gene id: 323848:NMUL_RS10995
uniprot id: Q2Y772
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323848:NMUL RS09445
gene id: 323848:NMUL_RS09445
uniprot id: Q2Y821
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

323848:NMUL RS06315
gene id: 323848:NMUL_RS06315
uniprot id: Q2Y9R7
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

323848:NMUL RS09875
gene id: 323848:NMUL_RS09875
uniprot id: Q2Y7U1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

323848:NMUL RS12205
gene id: 323848:NMUL_RS12205
uniprot id: A0A1H5XI98
uniprot id: Q2Y6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

323848:NMUL RS09470
gene id: 323848:NMUL_RS09470
uniprot id: Q2Y816
names: Similarity
messages: Belongs to the pirin family.

323848:NMUL RS04035
gene id: 323848:NMUL_RS04035
uniprot id: Q2YB03
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

323848:NMUL RS09705
gene id: 323848:NMUL_RS09705
uniprot id: Q2Y7X2
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Methylates ribosomal protein uL3 on a specific glutamine residue.

323848:NMUL RS02440
gene id: 323848:NMUL_RS02440
uniprot id: Q2YBU6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

323848:NMUL RS02370
gene id: 323848:NMUL_RS02370
uniprot id: A0A1H5RSH9
uniprot id: Q2YBW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS01845
gene id: 323848:NMUL_RS01845
uniprot id: Q2YC63
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

323848:NMUL RS04280
gene id: 323848:NMUL_RS04280
uniprot id: A0A1H5XUL0
uniprot id: Q2YAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323848:NMUL RS10060
gene id: 323848:NMUL_RS10060
uniprot id: Q2Y7Q4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS06360
gene id: 323848:NMUL_RS06360
uniprot id: Q2Y9Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323848:NMUL RS10275
gene id: 323848:NMUL_RS10275
uniprot id: Q2Y7L2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

323848:NMUL RS04165
gene id: 323848:NMUL_RS04165
uniprot id: Q2YAX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

323848:NMUL RS04550
gene id: 323848:NMUL_RS04550
uniprot id: Q2YAR0
names: Similarity
messages: Belongs to the citrate synthase family.

323848:NMUL RS03620
gene id: 323848:NMUL_RS03620
uniprot id: A0A1H5SU00
uniprot id: Q2YB78
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

323848:NMUL RS09390
gene id: 323848:NMUL_RS09390
uniprot id: Q2Y832
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

323848:NMUL RS03750
gene id: 323848:NMUL_RS03750
uniprot id: A0A1H5SXK8
uniprot id: Q2YB53
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

323848:NMUL RS08605
gene id: 323848:NMUL_RS08605
uniprot id: Q2Y8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323848:NMUL RS00915
gene id: 323848:NMUL_RS00915
uniprot id: Q2YCN8
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

323848:NMUL RS05780
gene id: 323848:NMUL_RS05780
uniprot id: A0A1H5UK63
uniprot id: Q2YA19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS08195
gene id: 323848:NMUL_RS08195
uniprot id: Q2Y8Q5
names: Similarity
messages: Belongs to the UPF0166 family.

323848:NMUL RS10935
gene id: 323848:NMUL_RS10935
uniprot id: Q2Y785
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

323848:NMUL RS08305
gene id: 323848:NMUL_RS08305
uniprot id: Q2Y8N6
names: Similarity
messages: Belongs to the YciI family.

323848:NMUL RS13820
gene id: 323848:NMUL_RS13820
uniprot id: Q2Y5N1
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

323848:NMUL RS10710
gene id: 323848:NMUL_RS10710
uniprot id: Q2Y7C9
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

323848:NMUL RS04025
gene id: 323848:NMUL_RS04025
uniprot id: A0A1H5SYP3
uniprot id: Q2YB05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323848:NMUL RS02480
gene id: 323848:NMUL_RS02480
uniprot id: Q2YBT8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS04740
gene id: 323848:NMUL_RS04740
uniprot id: Q2YAM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

323848:NMUL RS09505
gene id: 323848:NMUL_RS09505
uniprot id: Q2Y810
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

323848:NMUL RS00425
gene id: 323848:NMUL_RS00425
uniprot id: Q2YCY2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS01100
gene id: 323848:NMUL_RS01100
uniprot id: Q2YCK2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

323848:NMUL RS13710
gene id: 323848:NMUL_RS13710
uniprot id: Q2Y5Q2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

323848:NMUL RS00250
gene id: 323848:NMUL_RS00250
uniprot id: Q2YD13
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

323848:NMUL RS14000
gene id: 323848:NMUL_RS14000
uniprot id: Q2Y5J7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

323848:NMUL RS12490
gene id: 323848:NMUL_RS12490
uniprot id: Q2Y6D6
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

323848:NMUL RS03010
gene id: 323848:NMUL_RS03010
uniprot id: A0A1H5WFB3
uniprot id: Q2YBJ3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

323848:NMUL RS06635
gene id: 323848:NMUL_RS06635
uniprot id: Q2Y9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

323848:NMUL RS10640
gene id: 323848:NMUL_RS10640
uniprot id: Q2Y7E3
names: Similarity
messages: Belongs to the RelB/DinJ antitoxin family.

323848:NMUL RS04645
gene id: 323848:NMUL_RS04645
uniprot id: A0A1H5S899
uniprot id: Q2YAP0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

323848:NMUL RS01620
gene id: 323848:NMUL_RS01620
uniprot id: A0A1H5RNA2
uniprot id: Q2YCA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

323848:NMUL RS04575
gene id: 323848:NMUL_RS04575
uniprot id: Q2YAQ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

323848:NMUL RS03965
gene id: 323848:NMUL_RS03965
uniprot id: Q2YB13
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323848:NMUL RS03480
gene id: 323848:NMUL_RS03480
uniprot id: A0A1H5STY6
uniprot id: Q2YBA5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS02725
gene id: 323848:NMUL_RS02725
uniprot id: Q2YBP8
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

323848:NMUL RS10285
gene id: 323848:NMUL_RS10285
uniprot id: Q2Y7L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

323848:NMUL RS11030
gene id: 323848:NMUL_RS11030
uniprot id: Q2Y765
names: Similarity
messages: Belongs to the BolA/IbaG family.

323848:NMUL RS03800
gene id: 323848:NMUL_RS03800
uniprot id: Q2YB45
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

323848:NMUL RS05710
gene id: 323848:NMUL_RS05710
uniprot id: Q2YA32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

323848:NMUL RS04175
gene id: 323848:NMUL_RS04175
uniprot id: A0A1H5T0E3
uniprot id: Q2YAX5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

323848:NMUL RS04190
gene id: 323848:NMUL_RS04190
uniprot id: A0A1H5T0U2
uniprot id: Q2YAX2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

323848:NMUL RS12985
gene id: 323848:NMUL_RS12985
uniprot id: Q2Y643
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

323848:NMUL RS06990
gene id: 323848:NMUL_RS06990
uniprot id: Q2Y9E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

323848:NMUL RS06390
gene id: 323848:NMUL_RS06390
uniprot id: Q2Y9Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

323848:NMUL RS09975
gene id: 323848:NMUL_RS09975
uniprot id: A0A1H5TCW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

323848:NMUL RS06365
gene id: 323848:NMUL_RS06365
uniprot id: Q2Y9Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323848:NMUL RS04335
gene id: 323848:NMUL_RS04335
uniprot id: A0A1H5XSV2
uniprot id: Q2YAU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

323848:NMUL RS09760
gene id: 323848:NMUL_RS09760
uniprot id: A0A1H5TG15
uniprot id: Q2Y7W4
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

323848:NMUL RS07005
gene id: 323848:NMUL_RS07005
uniprot id: Q2Y9D8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

323848:NMUL RS03230
gene id: 323848:NMUL_RS03230
uniprot id: Q2YBF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

323848:NMUL RS07920
gene id: 323848:NMUL_RS07920
uniprot id: Q2Y8W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS07380
gene id: 323848:NMUL_RS07380
uniprot id: Q2Y966
names: Similarity
messages: Belongs to the disproportionating enzyme family.

323848:NMUL RS11505
gene id: 323848:NMUL_RS11505
uniprot id: Q2Y6X5
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

323848:NMUL RS10085
gene id: 323848:NMUL_RS10085
uniprot id: A0A1H5TBQ3
uniprot id: Q2Y7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

323848:NMUL RS07100
gene id: 323848:NMUL_RS07100
uniprot id: Q2Y9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS10900
gene id: 323848:NMUL_RS10900
uniprot id: A0A1H5X3Q0
uniprot id: Q2Y791
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

323848:NMUL RS11135
gene id: 323848:NMUL_RS11135
uniprot id: Q2Y744
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

323848:NMUL RS08470
gene id: 323848:NMUL_RS08470
uniprot id: Q2Y8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS08095
gene id: 323848:NMUL_RS08095
uniprot id: Q2Y8S5
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

323848:NMUL RS05775
gene id: 323848:NMUL_RS05775
uniprot id: A0A1H5UMC8
uniprot id: Q2YA20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

323848:NMUL RS13755
gene id: 323848:NMUL_RS13755
uniprot id: A0A1H5WJH0
uniprot id: Q2Y5P3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

323848:NMUL RS06325
gene id: 323848:NMUL_RS06325
uniprot id: A0A1H5VMT2
uniprot id: Q2Y9R5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

323848:NMUL RS04125
gene id: 323848:NMUL_RS04125
uniprot id: A0A1H5T020
uniprot id: Q2YAY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

323848:NMUL RS05025
gene id: 323848:NMUL_RS05025
uniprot id: Q2YAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323848:NMUL RS05430
gene id: 323848:NMUL_RS05430
uniprot id: Q2YA87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

323848:NMUL RS05330
gene id: 323848:NMUL_RS05330
uniprot id: Q2YAA7
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

323848:NMUL RS14045
gene id: 323848:NMUL_RS14045
uniprot id: A0A1H5UVD3
uniprot id: Q2Y5I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

323848:NMUL RS08660
gene id: 323848:NMUL_RS08660
uniprot id: Q2Y8H3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS00115
gene id: 323848:NMUL_RS00115
uniprot id: Q2YD39
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

323848:NMUL RS03940
gene id: 323848:NMUL_RS03940
uniprot id: A0A1H5SXT5
uniprot id: Q2YB18
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

323848:NMUL RS05760
gene id: 323848:NMUL_RS05760
uniprot id: Q2YA23
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

323848:NMUL RS10780
gene id: 323848:NMUL_RS10780
uniprot id: Q2Y7B4
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

323848:NMUL RS09805
gene id: 323848:NMUL_RS09805
uniprot id: Q2Y7V5
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

323848:NMUL RS10210
gene id: 323848:NMUL_RS10210
uniprot id: Q2Y7M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

323848:NMUL RS02670
gene id: 323848:NMUL_RS02670
uniprot id: Q2YBQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

323848:NMUL RS03410
gene id: 323848:NMUL_RS03410
uniprot id: Q2YBB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

323848:NMUL RS09305
gene id: 323848:NMUL_RS09305
uniprot id: Q2Y849
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS14645
gene id: 323848:NMUL_RS14645
uniprot id: Q2Y574
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

323848:NMUL RS07360
gene id: 323848:NMUL_RS07360
uniprot id: Q2Y968
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

323848:NMUL RS12590
gene id: 323848:NMUL_RS12590
uniprot id: A0A1H5VU90
uniprot id: Q2Y6B8
names: Similarity
messages: Belongs to the UPF0307 family.

323848:NMUL RS09155
gene id: 323848:NMUL_RS09155
uniprot id: Q2Y878
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323848:NMUL RS07400
gene id: 323848:NMUL_RS07400
uniprot id: Q2Y962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323848:NMUL RS01145
gene id: 323848:NMUL_RS01145
uniprot id: Q2YCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

323848:NMUL RS04475
gene id: 323848:NMUL_RS04475
uniprot id: Q2YAS3
names: Similarity
messages: Belongs to the peptidase S8 family.

323848:NMUL RS02040
gene id: 323848:NMUL_RS02040
uniprot id: Q2YC25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

323848:NMUL RS08550
gene id: 323848:NMUL_RS08550
uniprot id: Q2Y8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

323848:NMUL RS05555
gene id: 323848:NMUL_RS05555
uniprot id: Q2YA62
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

323848:NMUL RS04660
gene id: 323848:NMUL_RS04660
uniprot id: Q2YAN7
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

323848:NMUL RS09950
gene id: 323848:NMUL_RS09950
uniprot id: Q2Y7S6
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

323848:NMUL RS09770
gene id: 323848:NMUL_RS09770
uniprot id: A0A1H5TFN4
uniprot id: Q2Y7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

323848:NMUL RS03400
gene id: 323848:NMUL_RS03400
uniprot id: A0A1H5SRU3
uniprot id: Q2YBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

323848:NMUL RS03745
gene id: 323848:NMUL_RS03745
uniprot id: Q2YB54
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS09140
gene id: 323848:NMUL_RS09140
uniprot id: Q2Y881
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

323848:NMUL RS02585
gene id: 323848:NMUL_RS02585
uniprot id: A0A1H5RV63
uniprot id: Q2YBR8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

323848:NMUL RS03630
gene id: 323848:NMUL_RS03630
uniprot id: Q2YB76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS11830
gene id: 323848:NMUL_RS11830
uniprot id: Q2Y6R3
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

323848:NMUL RS12145
gene id: 323848:NMUL_RS12145
uniprot id: Q2Y6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

323848:NMUL RS12075
gene id: 323848:NMUL_RS12075
uniprot id: Q2Y6L4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS03550
gene id: 323848:NMUL_RS03550
uniprot id: Q2YB92
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

323848:NMUL RS05300
gene id: 323848:NMUL_RS05300
uniprot id: Q2YAB3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

323848:NMUL RS02355
gene id: 323848:NMUL_RS02355
uniprot id: A0A1H5RSA3
uniprot id: Q2YBW3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS06935
gene id: 323848:NMUL_RS06935
uniprot id: Q2Y9F2
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

323848:NMUL RS02120
gene id: 323848:NMUL_RS02120
uniprot id: Q2YC10
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS10770
gene id: 323848:NMUL_RS10770
uniprot id: A0A1H5X410
uniprot id: Q2Y7B6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

323848:NMUL RS10765
gene id: 323848:NMUL_RS10765
uniprot id: A0A1H5X5B4
uniprot id: Q2Y7B7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

323848:NMUL RS12980
gene id: 323848:NMUL_RS12980
uniprot id: Q2Y644
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS14215
gene id: 323848:NMUL_RS14215
uniprot id: Q2Y5F4
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

323848:NMUL RS09065
gene id: 323848:NMUL_RS09065
uniprot id: Q2Y896
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS03565
gene id: 323848:NMUL_RS03565
uniprot id: Q2YB89
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

323848:NMUL RS02750
gene id: 323848:NMUL_RS02750
uniprot id: A0A1H5RX01
uniprot id: Q2YBP3
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

323848:NMUL RS05370
gene id: 323848:NMUL_RS05370
uniprot id: A0A1H5SKC6
uniprot id: Q2YA99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

323848:NMUL RS02555
gene id: 323848:NMUL_RS02555
uniprot id: A0A1H5RVE5
uniprot id: Q2YBS3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

323848:NMUL RS03005
gene id: 323848:NMUL_RS03005
uniprot id: A0A1H5WGY0
uniprot id: Q2YBJ4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

323848:NMUL RS00940
gene id: 323848:NMUL_RS00940
uniprot id: A0A1H5Y877
uniprot id: Q2YCN3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS05805
gene id: 323848:NMUL_RS05805
uniprot id: Q2YA14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS14335
gene id: 323848:NMUL_RS14335
uniprot id: Q2Y5D0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

323848:NMUL RS02090
gene id: 323848:NMUL_RS02090
uniprot id: A0A1H5RPG0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

323848:NMUL RS10810
gene id: 323848:NMUL_RS10810
uniprot id: Q2Y7A8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

323848:NMUL RS01800
gene id: 323848:NMUL_RS01800
uniprot id: A0A1H5RM84
uniprot id: Q2YC72
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

323848:NMUL RS12760
gene id: 323848:NMUL_RS12760
uniprot id: Q2Y687
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

323848:NMUL RS00415
gene id: 323848:NMUL_RS00415
uniprot id: Q2YCY4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

323848:NMUL RS11070
gene id: 323848:NMUL_RS11070
uniprot id: Q2Y757
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

323848:NMUL RS03015
gene id: 323848:NMUL_RS03015
uniprot id: A0A1H5WEZ4
uniprot id: Q2YBJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

323848:NMUL RS04160
gene id: 323848:NMUL_RS04160
uniprot id: A0A1H5T0I5
uniprot id: Q2YAX8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

323848:NMUL RS08335
gene id: 323848:NMUL_RS08335
uniprot id: Q2Y8N0
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS06890
gene id: 323848:NMUL_RS06890
uniprot id: Q2Y9G0
names: Similarity
messages: Belongs to the MotB family.

323848:NMUL RS04005
gene id: 323848:NMUL_RS04005
uniprot id: A0A1H5SYC3
uniprot id: Q2YB09
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

323848:NMUL RS08190
gene id: 323848:NMUL_RS08190
uniprot id: A0A1H5VYL6
uniprot id: Q2Y8Q6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

323848:NMUL RS00635
gene id: 323848:NMUL_RS00635
uniprot id: Q2YCT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

323848:NMUL RS04450
gene id: 323848:NMUL_RS04450
uniprot id: Q2YAS6
names: Subcellular Location Annotation
messages: Cytoplasm

323848:NMUL RS04325
gene id: 323848:NMUL_RS04325
uniprot id: A0A1H5XSZ6
uniprot id: Q2YAU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

323848:NMUL RS01635
gene id: 323848:NMUL_RS01635
uniprot id: A0A1H5RKX5
uniprot id: Q2YCA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

323848:NMUL RS01410
gene id: 323848:NMUL_RS01410
uniprot id: Q2YCE7
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

323848:NMUL RS13265
gene id: 323848:NMUL_RS13265
uniprot id: A0A1H5TT45
uniprot id: Q2Y5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

323848:NMUL RS05830
gene id: 323848:NMUL_RS05830
uniprot id: A0A1H5UMG0
uniprot id: Q2YA09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

323848:NMUL RS02330
gene id: 323848:NMUL_RS02330
uniprot id: Q2YBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

323848:NMUL RS09025
gene id: 323848:NMUL_RS09025
uniprot id: Q2Y8A4
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

323848:NMUL RS01585
gene id: 323848:NMUL_RS01585
uniprot id: Q2YCB3
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS03115
gene id: 323848:NMUL_RS03115
uniprot id: Q2YBH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

323848:NMUL RS05770
gene id: 323848:NMUL_RS05770
uniprot id: Q2YA21
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS07925
gene id: 323848:NMUL_RS07925
uniprot id: Q2Y8V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323848:NMUL RS09765
gene id: 323848:NMUL_RS09765
uniprot id: A0A1H5TFS5
uniprot id: Q2Y7W3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

323848:NMUL RS12275
gene id: 323848:NMUL_RS12275
uniprot id: Q2Y6H7
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS10215
gene id: 323848:NMUL_RS10215
uniprot id: Q2Y7M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

323848:NMUL RS11710
gene id: 323848:NMUL_RS11710
uniprot id: Q2Y6T5
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

323848:NMUL RS02960
gene id: 323848:NMUL_RS02960
uniprot id: A0A1H5WHH1
uniprot id: Q2YBK3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

323848:NMUL RS07375
gene id: 323848:NMUL_RS07375
uniprot id: Q2Y967
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

323848:NMUL RS03735
gene id: 323848:NMUL_RS03735
uniprot id: A0A1H5SV54
uniprot id: Q2YB56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

323848:NMUL RS05630
gene id: 323848:NMUL_RS05630
uniprot id: A0A1H5SL53
uniprot id: Q2YA47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

323848:NMUL RS09400
gene id: 323848:NMUL_RS09400
uniprot id: A0A1H5W9Y9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323848:NMUL RS13875
gene id: 323848:NMUL_RS13875
uniprot id: Q2Y5M1
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS02365
gene id: 323848:NMUL_RS02365
uniprot id: A0A1H5RSF4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS05225
gene id: 323848:NMUL_RS05225
uniprot id: Q2YAC6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

323848:NMUL RS04315
gene id: 323848:NMUL_RS04315
uniprot id: A0A1H5XSU6
uniprot id: Q2YAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

323848:NMUL RS01945
gene id: 323848:NMUL_RS01945
uniprot id: Q2YC44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323848:NMUL RS05065
gene id: 323848:NMUL_RS05065
uniprot id: Q2YAF7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase S45 family.
messages: Binds 1 Ca(2+) ion per dimer.

323848:NMUL RS14270
gene id: 323848:NMUL_RS14270
uniprot id: Q2Y5E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

323848:NMUL RS10420
gene id: 323848:NMUL_RS10420
uniprot id: A0A1H5T7F5
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

323848:NMUL RS12800
gene id: 323848:NMUL_RS12800
uniprot id: Q2Y680
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

323848:NMUL RS10320
gene id: 323848:NMUL_RS10320
uniprot id: A0A1H5TAM6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323848:NMUL RS13080
gene id: 323848:NMUL_RS13080
uniprot id: Q2Y623
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323848:NMUL RS06060
gene id: 323848:NMUL_RS06060
uniprot id: Q2Y9W6
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

323848:NMUL RS03120
gene id: 323848:NMUL_RS03120
uniprot id: A0A1H5WE39
uniprot id: Q2YBH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

323848:NMUL RS13350
gene id: 323848:NMUL_RS13350
uniprot id: A0A1H5TS00
names: Similarity
messages: Belongs to the TrpC family.

323848:NMUL RS04095
gene id: 323848:NMUL_RS04095
uniprot id: A0A1H5SZL0
uniprot id: Q2YAZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

323848:NMUL RS07825
gene id: 323848:NMUL_RS07825
uniprot id: Q2Y8X9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323848:NMUL RS09905
gene id: 323848:NMUL_RS09905
uniprot id: Q2Y7T5
names: Similarity
messages: Belongs to the peptidase S8 family.

323848:NMUL RS02220
gene id: 323848:NMUL_RS02220
uniprot id: Q2YBZ0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS04320
gene id: 323848:NMUL_RS04320
uniprot id: A0A1H5XSM6
uniprot id: Q2YAU8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

323848:NMUL RS04040
gene id: 323848:NMUL_RS04040
uniprot id: A0A1H5T0V2
uniprot id: Q2YB02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

323848:NMUL RS04065
gene id: 323848:NMUL_RS04065
uniprot id: A0A1H5SZ74
uniprot id: Q2YAZ7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

323848:NMUL RS06920
gene id: 323848:NMUL_RS06920
uniprot id: Q2Y9F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323848:NMUL RS10185
gene id: 323848:NMUL_RS10185
uniprot id: A0A1H5TAG7
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

323848:NMUL RS12320
gene id: 323848:NMUL_RS12320
uniprot id: Q2Y6G8
names: Similarity
messages: Belongs to the peptidase A24 family.

323848:NMUL RS04085
gene id: 323848:NMUL_RS04085
uniprot id: A0A1H5T195
uniprot id: Q2YAZ3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

323848:NMUL RS01825
gene id: 323848:NMUL_RS01825
uniprot id: A0A1H5RM43
uniprot id: Q2YC67
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS10360
gene id: 323848:NMUL_RS10360
uniprot id: A0A1H5T857
uniprot id: Q2Y7J7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

323848:NMUL RS03335
gene id: 323848:NMUL_RS03335
uniprot id: Q2YBD3
names: Similarity
messages: Belongs to the polysaccharide synthase family.

323848:NMUL RS03600
gene id: 323848:NMUL_RS03600
uniprot id: Q2YB82
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS11470
gene id: 323848:NMUL_RS11470
uniprot id: Q2Y6Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323848:NMUL RS06525
gene id: 323848:NMUL_RS06525
uniprot id: A0A1H5VPS8
uniprot id: Q2Y9M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

323848:NMUL RS05365
gene id: 323848:NMUL_RS05365
uniprot id: Q2YAA0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323848:NMUL RS01890
gene id: 323848:NMUL_RS01890
uniprot id: Q2YC55
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

323848:NMUL RS02335
gene id: 323848:NMUL_RS02335
uniprot id: Q2YBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

323848:NMUL RS09675
gene id: 323848:NMUL_RS09675
uniprot id: Q2Y7X8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

323848:NMUL RS12505
gene id: 323848:NMUL_RS12505
uniprot id: Q2Y6D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS08440
gene id: 323848:NMUL_RS08440
uniprot id: A0A1H5X1Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

323848:NMUL RS05510
gene id: 323848:NMUL_RS05510
uniprot id: Q2YA71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323848:NMUL RS08775
gene id: 323848:NMUL_RS08775
uniprot id: Q2Y8F0
names: Similarity
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.

323848:NMUL RS13140
gene id: 323848:NMUL_RS13140
uniprot id: Q2Y611
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

323848:NMUL RS08345
gene id: 323848:NMUL_RS08345
uniprot id: Q2Y8M8
names: Similarity
messages: Belongs to the peptidase C40 family.

323848:NMUL RS12420
gene id: 323848:NMUL_RS12420
uniprot id: Q2Y6E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS08420
gene id: 323848:NMUL_RS08420
uniprot id: Q2Y8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS05305
gene id: 323848:NMUL_RS05305
uniprot id: A0A1H5SJ84
uniprot id: Q2YAB2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

323848:NMUL RS00610
gene id: 323848:NMUL_RS00610
uniprot id: Q2YCU3
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

323848:NMUL RS14010
gene id: 323848:NMUL_RS14010
uniprot id: Q2Y5J5
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

323848:NMUL RS12380
gene id: 323848:NMUL_RS12380
uniprot id: Q2Y6F6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS10355
gene id: 323848:NMUL_RS10355
uniprot id: Q2Y7J8
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS07740
gene id: 323848:NMUL_RS07740
uniprot id: Q2Y8Z5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

323848:NMUL RS14375
gene id: 323848:NMUL_RS14375
uniprot id: Q2Y5C4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS09230
gene id: 323848:NMUL_RS09230
uniprot id: A0A1H5V944
uniprot id: Q2Y863
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

323848:NMUL RS00960
gene id: 323848:NMUL_RS00960
uniprot id: Q2YCM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

323848:NMUL RS13700
gene id: 323848:NMUL_RS13700
uniprot id: Q2Y5Q4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

323848:NMUL RS11640
gene id: 323848:NMUL_RS11640
uniprot id: Q2Y6U8
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

323848:NMUL RS03235
gene id: 323848:NMUL_RS03235
uniprot id: A0A1H5XQK3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

323848:NMUL RS14410
gene id: 323848:NMUL_RS14410
uniprot id: A0A1H5WNI9
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

323848:NMUL RS13720
gene id: 323848:NMUL_RS13720
uniprot id: Q2Y5Q0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

323848:NMUL RS06500
gene id: 323848:NMUL_RS06500
uniprot id: Q2Y9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

323848:NMUL RS05835
gene id: 323848:NMUL_RS05835
uniprot id: Q2YA08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323848:NMUL RS04000
gene id: 323848:NMUL_RS04000
uniprot id: Q2YB10
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

323848:NMUL RS05490
gene id: 323848:NMUL_RS05490
uniprot id: A0A1H5SJA0
uniprot id: Q2YA75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

323848:NMUL RS03225
gene id: 323848:NMUL_RS03225
uniprot id: Q2YBF4
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

323848:NMUL RS11560
gene id: 323848:NMUL_RS11560
uniprot id: Q2Y6W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

323848:NMUL RS05410
gene id: 323848:NMUL_RS05410
uniprot id: A0A1H5SIG4
uniprot id: Q2YA91
names: Similarity
messages: Belongs to the UPF0434 family.

323848:NMUL RS02505
gene id: 323848:NMUL_RS02505
uniprot id: Q2YBT3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

323848:NMUL RS03000
gene id: 323848:NMUL_RS03000
uniprot id: Q2YBJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

323848:NMUL RS10440
gene id: 323848:NMUL_RS10440
uniprot id: Q2Y7I0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

323848:NMUL RS06085
gene id: 323848:NMUL_RS06085
uniprot id: Q2Y9W1
names: Similarity
messages: Belongs to the ArsC family.

323848:NMUL RS00690
gene id: 323848:NMUL_RS00690
uniprot id: Q2YCS8
names: Similarity
messages: Belongs to the GARS family.

323848:NMUL RS06290
gene id: 323848:NMUL_RS06290
uniprot id: Q2Y9S2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

323848:NMUL RS05290
gene id: 323848:NMUL_RS05290
uniprot id: Q2YAB5
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

323848:NMUL RS11405
gene id: 323848:NMUL_RS11405
uniprot id: Q2Y6Z2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS05495
gene id: 323848:NMUL_RS05495
uniprot id: A0A1H5SJ98
uniprot id: Q2YA74
names: Similarity
messages: Belongs to the UPF0234 family.

323848:NMUL RS01430
gene id: 323848:NMUL_RS01430
uniprot id: A0A1H5V390
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

323848:NMUL RS08085
gene id: 323848:NMUL_RS08085
uniprot id: Q2Y8S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

323848:NMUL RS09780
gene id: 323848:NMUL_RS09780
uniprot id: A0A1H5TFG3
uniprot id: Q2Y7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

323848:NMUL RS01765
gene id: 323848:NMUL_RS01765
uniprot id: A0A1H5RMD9
uniprot id: Q2YC79
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

323848:NMUL RS05390
gene id: 323848:NMUL_RS05390
uniprot id: Q2YA95
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS02720
gene id: 323848:NMUL_RS02720
uniprot id: A0A1H5RYR1
uniprot id: Q2YBP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

323848:NMUL RS13305
gene id: 323848:NMUL_RS13305
uniprot id: A0A1H5TQP7
uniprot id: Q2Y5X8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

323848:NMUL RS12190
gene id: 323848:NMUL_RS12190
uniprot id: Q2Y6J3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

323848:NMUL RS03555
gene id: 323848:NMUL_RS03555
uniprot id: A0A1H5SV47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS13295
gene id: 323848:NMUL_RS13295
uniprot id: Q2Y5Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.

323848:NMUL RS14170
gene id: 323848:NMUL_RS14170
uniprot id: A0A1H5UWW9
uniprot id: Q2Y5G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

323848:NMUL RS01995
gene id: 323848:NMUL_RS01995
uniprot id: Q2YC34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

323848:NMUL RS05310
gene id: 323848:NMUL_RS05310
uniprot id: Q2YAB1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323848:NMUL RS14515
gene id: 323848:NMUL_RS14515
uniprot id: Q2Y598
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

323848:NMUL RS02560
gene id: 323848:NMUL_RS02560
uniprot id: A0A1H5RX91
uniprot id: Q2YBS2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323848:NMUL RS09310
gene id: 323848:NMUL_RS09310
uniprot id: Q2Y848
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

323848:NMUL RS02140
gene id: 323848:NMUL_RS02140
uniprot id: Q2YC06
names: Similarity
names: Subunit
messages: Belongs to the CMP-NeuNAc synthase family.
messages: Belongs to the KdsC family.
messages: Homotetramer.

323848:NMUL RS01910
gene id: 323848:NMUL_RS01910
uniprot id: A0A1H5RMP5
uniprot id: Q2YC51
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

323848:NMUL RS09145
gene id: 323848:NMUL_RS09145
uniprot id: Q2Y880
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS04610
gene id: 323848:NMUL_RS04610
uniprot id: Q2YAP7
names: Similarity
messages: Belongs to the PrpD family.

323848:NMUL RS04015
gene id: 323848:NMUL_RS04015
uniprot id: A0A1H5T0Q9
uniprot id: Q2YB07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

323848:NMUL RS05160
gene id: 323848:NMUL_RS05160
uniprot id: Q2YAD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

323848:NMUL RS02400
gene id: 323848:NMUL_RS02400
uniprot id: Q2YBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

323848:NMUL RS03375
gene id: 323848:NMUL_RS03375
uniprot id: Q2YBC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

323848:NMUL RS03530
gene id: 323848:NMUL_RS03530
uniprot id: A0A1H5SUM5
uniprot id: Q2YB96
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

323848:NMUL RS04580
gene id: 323848:NMUL_RS04580
uniprot id: A0A1H5S789
uniprot id: Q2YAQ4
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

323848:NMUL RS03430
gene id: 323848:NMUL_RS03430
uniprot id: Q2YBB4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Homohexamer. Dimer of a homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.

323848:NMUL RS12895
gene id: 323848:NMUL_RS12895
uniprot id: Q2Y661
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

323848:NMUL RS09925
gene id: 323848:NMUL_RS09925
uniprot id: Q2Y7T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS13895
gene id: 323848:NMUL_RS13895
uniprot id: Q2Y5L7
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 2 family.

323848:NMUL RS03515
gene id: 323848:NMUL_RS03515
uniprot id: Q2YB99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323848:NMUL RS10050
gene id: 323848:NMUL_RS10050
uniprot id: Q2Y7Q6
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

323848:NMUL RS07115
gene id: 323848:NMUL_RS07115
uniprot id: Q2Y9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323848:NMUL RS12280
gene id: 323848:NMUL_RS12280
uniprot id: Q2Y6H6
names: Similarity
messages: Belongs to the GSP E family.

323848:NMUL RS12565
gene id: 323848:NMUL_RS12565
uniprot id: Q2Y6C3
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

323848:NMUL RS06065
gene id: 323848:NMUL_RS06065
uniprot id: Q2Y9W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

323848:NMUL RS09920
gene id: 323848:NMUL_RS09920
uniprot id: Q2Y7T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS10205
gene id: 323848:NMUL_RS10205
uniprot id: A0A1H5TA41
uniprot id: Q2Y7M5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

323848:NMUL RS02035
gene id: 323848:NMUL_RS02035
uniprot id: Q2YC26
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

323848:NMUL RS13020
gene id: 323848:NMUL_RS13020
uniprot id: A0A1H5TUM7
uniprot id: Q2Y636
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

323848:NMUL RS13545
gene id: 323848:NMUL_RS13545
uniprot id: Q2Y5T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

323848:NMUL RS11255
gene id: 323848:NMUL_RS11255
uniprot id: A0A1H5VFS9
uniprot id: Q2Y720
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

323848:NMUL RS00995
gene id: 323848:NMUL_RS00995
uniprot id: A0A1H5V523
uniprot id: Q2YCM2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

323848:NMUL RS00730
gene id: 323848:NMUL_RS00730
uniprot id: Q2YCS1
names: Similarity
messages: Belongs to the NodU/CmcH family.

323848:NMUL RS01165
gene id: 323848:NMUL_RS01165
uniprot id: Q2YCI9
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

323848:NMUL RS04170
gene id: 323848:NMUL_RS04170
uniprot id: A0A1H5T0M0
uniprot id: Q2YAX6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

323848:NMUL RS10270
gene id: 323848:NMUL_RS10270
uniprot id: Q2Y7L3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

323848:NMUL RS14120
gene id: 323848:NMUL_RS14120
uniprot id: Q2Y5H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

323848:NMUL RS06430
gene id: 323848:NMUL_RS06430
uniprot id: Q2Y9P2
names: Similarity
messages: Belongs to the YkuD family.

323848:NMUL RS09520
gene id: 323848:NMUL_RS09520
uniprot id: A0A1H5WBU8
uniprot id: Q2Y807
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS10880
gene id: 323848:NMUL_RS10880
uniprot id: Q2Y795
names: Function
names: Similarity
messages: Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
messages: Belongs to the biotin--protein ligase family.

323848:NMUL RS08815
gene id: 323848:NMUL_RS08815
uniprot id: Q2Y8E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS06340
gene id: 323848:NMUL_RS06340
uniprot id: Q2Y9R1
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

323848:NMUL RS12335
gene id: 323848:NMUL_RS12335
uniprot id: Q2Y6G5
names: Similarity
messages: Belongs to the peptidase S13 family.

323848:NMUL RS12130
gene id: 323848:NMUL_RS12130
uniprot id: Q2Y6K3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

323848:NMUL RS02210
gene id: 323848:NMUL_RS02210
uniprot id: Q2YBZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

323848:NMUL RS01230
gene id: 323848:NMUL_RS01230
uniprot id: Q2YCH8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

323848:NMUL RS00420
gene id: 323848:NMUL_RS00420
uniprot id: Q2YCY3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

323848:NMUL RS11865
gene id: 323848:NMUL_RS11865
uniprot id: Q2Y6Q6
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

323848:NMUL RS05950
gene id: 323848:NMUL_RS05950
uniprot id: Q2Y9Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS14155
gene id: 323848:NMUL_RS14155
uniprot id: A0A1H5UWC9
uniprot id: Q2Y5G5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

323848:NMUL RS00110
gene id: 323848:NMUL_RS00110
uniprot id: A0A1H5WQI7
uniprot id: Q2YD40
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

323848:NMUL RS07010
gene id: 323848:NMUL_RS07010
uniprot id: Q2Y9D7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

323848:NMUL RS03220
gene id: 323848:NMUL_RS03220
uniprot id: Q2YBF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PsiE family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS05485
gene id: 323848:NMUL_RS05485
uniprot id: A0A1H5SL48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm

323848:NMUL RS09615
gene id: 323848:NMUL_RS09615
uniprot id: Q2Y7Y8
names: Function
names: Similarity
messages: Belongs to the transposase IS30 family.
messages: Required for the transposition of the insertion element.

323848:NMUL RS03710
gene id: 323848:NMUL_RS03710
uniprot id: A0A1H5SV08
uniprot id: Q2YB61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

323848:NMUL RS10535
gene id: 323848:NMUL_RS10535
uniprot id: A0A1H5Y8W3
names: Similarity
messages: Belongs to the bleomycin resistance protein family.

323848:NMUL RS09715
gene id: 323848:NMUL_RS09715
uniprot id: Q2Y7X0
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

323848:NMUL RS02490
gene id: 323848:NMUL_RS02490
uniprot id: A0A1H5RU23
uniprot id: Q2YBT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

323848:NMUL RS03490
gene id: 323848:NMUL_RS03490
uniprot id: Q2YBA3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

323848:NMUL RS03435
gene id: 323848:NMUL_RS03435
uniprot id: Q2YBB3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

323848:NMUL RS12170
gene id: 323848:NMUL_RS12170
uniprot id: Q2Y6J5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

323848:NMUL RS14805
gene id: 323848:NMUL_RS14805
uniprot id: Q2YBM9
names: Similarity
messages: Belongs to the peptidase S8 family.

323848:NMUL RS04075
gene id: 323848:NMUL_RS04075
uniprot id: A0A1H5SZ80
uniprot id: Q2YAZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

323848:NMUL RS14080
gene id: 323848:NMUL_RS14080
uniprot id: Q2Y5I0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

323848:NMUL RS12655
gene id: 323848:NMUL_RS12655
uniprot id: Q2Y6A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

323848:NMUL RS03905
gene id: 323848:NMUL_RS03905
uniprot id: Q2YB25
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

323848:NMUL RS12625
gene id: 323848:NMUL_RS12625
uniprot id: Q2Y6B1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

323848:NMUL RS11115
gene id: 323848:NMUL_RS11115
uniprot id: A0A1H5VHC9
uniprot id: Q2Y748
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

323848:NMUL RS11905
gene id: 323848:NMUL_RS11905
uniprot id: Q2Y6P9
names: Cofactor
messages: Binds 3 heme c groups covalently per subunit.

323848:NMUL RS03525
gene id: 323848:NMUL_RS03525
uniprot id: A0A1H5SSX8
uniprot id: Q2YB97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

323848:NMUL RS06310
gene id: 323848:NMUL_RS06310
uniprot id: Q2Y9R8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

323848:NMUL RS12370
gene id: 323848:NMUL_RS12370
uniprot id: Q2Y6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamB family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323848:NMUL RS12885
gene id: 323848:NMUL_RS12885
uniprot id: Q2Y663
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

323848:NMUL RS09855
gene id: 323848:NMUL_RS09855
uniprot id: A0A1H5TEN2
uniprot id: Q2Y7U5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

323848:NMUL RS01105
gene id: 323848:NMUL_RS01105
uniprot id: A0A1H5V5P7
uniprot id: Q2YCK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

323848:NMUL RS03510
gene id: 323848:NMUL_RS03510
uniprot id: Q2YBA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

323848:NMUL RS13930
gene id: 323848:NMUL_RS13930
uniprot id: Q2Y5L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

323848:NMUL RS11730
gene id: 323848:NMUL_RS11730
uniprot id: A0A1H5U515
uniprot id: Q2Y6T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

323848:NMUL RS13610
gene id: 323848:NMUL_RS13610
uniprot id: A0A1H5WHY0
uniprot id: Q2Y5S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

323848:NMUL RS12230
gene id: 323848:NMUL_RS12230
uniprot id: A0A1H5XGZ9
uniprot id: Q2Y6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

323848:NMUL RS11095
gene id: 323848:NMUL_RS11095
uniprot id: Q2Y752
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

323848:NMUL RS08170
gene id: 323848:NMUL_RS08170
uniprot id: Q2Y8R0
names: Similarity
messages: Belongs to the histone deacetylase family.

323848:NMUL RS09425
gene id: 323848:NMUL_RS09425
uniprot id: Q2Y825
names: Similarity
messages: Belongs to the DEAD box helicase family.

323848:NMUL RS09810
gene id: 323848:NMUL_RS09810
uniprot id: Q2Y7V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

323848:NMUL RS04960
gene id: 323848:NMUL_RS04960
uniprot id: Q2YAH8
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS13750
gene id: 323848:NMUL_RS13750
uniprot id: Q2Y5P4
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

323848:NMUL RS14125
gene id: 323848:NMUL_RS14125
uniprot id: Q2Y5H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323848:NMUL RS12670
gene id: 323848:NMUL_RS12670
uniprot id: A0A1H5VUD2
uniprot id: Q2Y6A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

323848:NMUL RS02010
gene id: 323848:NMUL_RS02010
uniprot id: Q2YC31
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

323848:NMUL RS01655
gene id: 323848:NMUL_RS01655
uniprot id: Q2YCA0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS11945
gene id: 323848:NMUL_RS11945
uniprot id: Q2Y6P1
names: Similarity
messages: Belongs to the glutamine synthetase family.

323848:NMUL RS00965
gene id: 323848:NMUL_RS00965
uniprot id: Q2YCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

323848:NMUL RS03070
gene id: 323848:NMUL_RS03070
uniprot id: Q2YBI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

323848:NMUL RS00260
gene id: 323848:NMUL_RS00260
uniprot id: A0A1H5Y9D3
uniprot id: Q2YD11
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323848:NMUL RS13600
gene id: 323848:NMUL_RS13600
uniprot id: A0A1H5WJ46
uniprot id: Q2Y5S4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

323848:NMUL RS04630
gene id: 323848:NMUL_RS04630
uniprot id: Q2YAP3
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

323848:NMUL RS03200
gene id: 323848:NMUL_RS03200
uniprot id: Q2YBF9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

323848:NMUL RS12850
gene id: 323848:NMUL_RS12850
uniprot id: Q2Y670
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS04770
gene id: 323848:NMUL_RS04770
uniprot id: Q2YAL5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

323848:NMUL RS02445
gene id: 323848:NMUL_RS02445
uniprot id: Q2YBU5
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

323848:NMUL RS00675
gene id: 323848:NMUL_RS00675
uniprot id: Q2YCT0
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

323848:NMUL RS06535
gene id: 323848:NMUL_RS06535
uniprot id: Q2Y9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

323848:NMUL RS00650
gene id: 323848:NMUL_RS00650
uniprot id: Q2YCT4
names: Similarity
messages: Belongs to the peptidase M24B family.

323848:NMUL RS04110
gene id: 323848:NMUL_RS04110
uniprot id: A0A1H5SZU5
uniprot id: Q2YAY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

323848:NMUL RS12350
gene id: 323848:NMUL_RS12350
uniprot id: Q2Y6G2
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

323848:NMUL RS04080
gene id: 323848:NMUL_RS04080
uniprot id: A0A1H5T1E1
uniprot id: Q2YAZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

323848:NMUL RS05855
gene id: 323848:NMUL_RS05855
uniprot id: Q2YA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323848:NMUL RS08685
gene id: 323848:NMUL_RS08685
uniprot id: Q2Y8G7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323848:NMUL RS04135
gene id: 323848:NMUL_RS04135
uniprot id: A0A1H5T043
uniprot id: Q2YAY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

323848:NMUL RS05720
gene id: 323848:NMUL_RS05720
uniprot id: Q2YA30
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

323848:NMUL RS02500
gene id: 323848:NMUL_RS02500
uniprot id: Q2YBT4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS08580
gene id: 323848:NMUL_RS08580
uniprot id: A0A1H5X007
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS01225
gene id: 323848:NMUL_RS01225
uniprot id: Q2YCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

323848:NMUL RS00505
gene id: 323848:NMUL_RS00505
uniprot id: Q2YCW6
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

323848:NMUL RS04115
gene id: 323848:NMUL_RS04115
uniprot id: A0A1H5T1M8
uniprot id: Q2YAY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

323848:NMUL RS04555
gene id: 323848:NMUL_RS04555
uniprot id: Q2YAQ9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

323848:NMUL RS13355
gene id: 323848:NMUL_RS13355
uniprot id: A0A1H5TQA6
uniprot id: Q2Y5W9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS07220
gene id: 323848:NMUL_RS07220
uniprot id: Q2Y995
names: Subcellular Location Annotation
messages: Secreted

323848:NMUL RS15660
gene id: 323848:NMUL_RS15660
uniprot id: A0A1H5XWK5
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

323848:NMUL RS03910
gene id: 323848:NMUL_RS03910
uniprot id: Q2YB24
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

323848:NMUL RS01110
gene id: 323848:NMUL_RS01110
uniprot id: A0A1H5V497
uniprot id: Q2YCK0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

323848:NMUL RS00360
gene id: 323848:NMUL_RS00360
uniprot id: Q2YCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

323848:NMUL RS04585
gene id: 323848:NMUL_RS04585
uniprot id: Q2YAQ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

323848:NMUL RS12435
gene id: 323848:NMUL_RS12435
uniprot id: Q2Y6E5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

323848:NMUL RS02540
gene id: 323848:NMUL_RS02540
uniprot id: A0A1H5RV39
uniprot id: Q2YBS6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

323848:NMUL RS02755
gene id: 323848:NMUL_RS02755
uniprot id: A0A1H5RX22
uniprot id: Q2YBP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

323848:NMUL RS06945
gene id: 323848:NMUL_RS06945
uniprot id: Q2Y9F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

323848:NMUL RS13775
gene id: 323848:NMUL_RS13775
uniprot id: Q2Y5N9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

323848:NMUL RS12395
gene id: 323848:NMUL_RS12395
uniprot id: A0A1H5W1K2
uniprot id: Q2Y6F3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

323848:NMUL RS01170
gene id: 323848:NMUL_RS01170
uniprot id: A0A1H5V3M1
uniprot id: Q2YCI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

323848:NMUL RS04535
gene id: 323848:NMUL_RS04535
uniprot id: Q2YAR3
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

323848:NMUL RS05395
gene id: 323848:NMUL_RS05395
uniprot id: Q2YA94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323848:NMUL RS01075
gene id: 323848:NMUL_RS01075
uniprot id: A0A1H5V4M9
uniprot id: Q2YCK7
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

323848:NMUL RS01675
gene id: 323848:NMUL_RS01675
uniprot id: Q2YC96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

323848:NMUL RS13005
gene id: 323848:NMUL_RS13005
uniprot id: A0A1H5TV69
uniprot id: Q2Y639
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

323848:NMUL RS08965
gene id: 323848:NMUL_RS08965
uniprot id: Q2Y8B4
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS06025
gene id: 323848:NMUL_RS06025
uniprot id: Q2Y9X3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323848:NMUL RS05810
gene id: 323848:NMUL_RS05810
uniprot id: Q2YA13
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS00680
gene id: 323848:NMUL_RS00680
uniprot id: Q2YCS9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

323848:NMUL RS03040
gene id: 323848:NMUL_RS03040
uniprot id: Q2YBI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

323848:NMUL RS03085
gene id: 323848:NMUL_RS03085
uniprot id: Q2YBH9
names: Subcellular Location Annotation
messages: Membrane

323848:NMUL RS04515
gene id: 323848:NMUL_RS04515
uniprot id: Q2YAR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

323848:NMUL RS09220
gene id: 323848:NMUL_RS09220
uniprot id: Q2Y865
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

323848:NMUL RS05585
gene id: 323848:NMUL_RS05585
uniprot id: Q2YA56
names: Similarity
messages: Belongs to the phosphohexose mutase family.

323848:NMUL RS07085
gene id: 323848:NMUL_RS07085
uniprot id: Q2Y9C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323848:NMUL RS03050
gene id: 323848:NMUL_RS03050
uniprot id: Q2YBI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

323848:NMUL RS14235
gene id: 323848:NMUL_RS14235
uniprot id: A0A1H5UVC8
uniprot id: Q2Y5F0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

323848:NMUL RS13825
gene id: 323848:NMUL_RS13825
uniprot id: Q2Y5N0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

323848:NMUL RS10245
gene id: 323848:NMUL_RS10245
uniprot id: A0A1H5T9J5
uniprot id: Q2Y7L8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

323848:NMUL RS14445
gene id: 323848:NMUL_RS14445
uniprot id: A0A1H5WPA7
uniprot id: Q2Y5A9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323848:NMUL RS01790
gene id: 323848:NMUL_RS01790
uniprot id: Q2YC74
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

323848:NMUL RS00095
gene id: 323848:NMUL_RS00095
uniprot id: A0A1H5WQC8
uniprot id: Q2YD43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

323848:NMUL RS02715
gene id: 323848:NMUL_RS02715
uniprot id: Q2YBQ0
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

323848:NMUL RS04510
gene id: 323848:NMUL_RS04510
uniprot id: Q2YAR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323848:NMUL RS06980
gene id: 323848:NMUL_RS06980
uniprot id: Q2Y9E3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

323848:NMUL RS07325
gene id: 323848:NMUL_RS07325
uniprot id: Q2Y974
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

323848:NMUL RS10860
gene id: 323848:NMUL_RS10860
uniprot id: Q2Y799
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

323848:NMUL RS05705
gene id: 323848:NMUL_RS05705
uniprot id: Q2YA33
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.

323848:NMUL RS14110
gene id: 323848:NMUL_RS14110
uniprot id: A0A1H5UV66
uniprot id: Q2Y5H4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

323848:NMUL RS11615
gene id: 323848:NMUL_RS11615
uniprot id: Q2Y6V3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

323848:NMUL RS05295
gene id: 323848:NMUL_RS05295
uniprot id: Q2YAB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

323848:NMUL RS12375
gene id: 323848:NMUL_RS12375
uniprot id: Q2Y6F7
names: Similarity
messages: Belongs to the YfgM family.

323848:NMUL RS11005
gene id: 323848:NMUL_RS11005
uniprot id: Q2Y770
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323848:NMUL RS14245
gene id: 323848:NMUL_RS14245
uniprot id: Q2Y5E8
names: Similarity
messages: Belongs to the peptidase M16 family.