323261:NOC RS15015
gene id: 323261:NOC_RS15015
uniprot id: Q3J7B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS07080
gene id: 323261:NOC_RS07080
uniprot id: Q3JBJ7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

323261:NOC RS03090
gene id: 323261:NOC_RS03090
uniprot id: Q3JDL4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS03345
gene id: 323261:NOC_RS03345
uniprot id: Q3JDG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323261:NOC RS14140
gene id: 323261:NOC_RS14140
uniprot id: Q3J7T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

323261:NOC RS14635
gene id: 323261:NOC_RS14635
uniprot id: Q3J7I9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

323261:NOC RS07105
gene id: 323261:NOC_RS07105
uniprot id: Q3JBJ2
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

323261:NOC RS12055
gene id: 323261:NOC_RS12055
uniprot id: Q3J8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

323261:NOC RS14595
gene id: 323261:NOC_RS14595
uniprot id: Q3J7J7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

323261:NOC RS14975
gene id: 323261:NOC_RS14975
uniprot id: Q3J7C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

323261:NOC RS04945
gene id: 323261:NOC_RS04945
uniprot id: Q3JCM5
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

323261:NOC RS13660
gene id: 323261:NOC_RS13660
uniprot id: Q3J827
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

323261:NOC RS10870
gene id: 323261:NOC_RS10870
uniprot id: Q3J9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS09950
gene id: 323261:NOC_RS09950
uniprot id: Q3JA31
names: Similarity
messages: Belongs to the CbbQ/NirQ/NorQ/GpvN family.

323261:NOC RS01330
gene id: 323261:NOC_RS01330
uniprot id: Q3JEJ6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

323261:NOC RS01885
gene id: 323261:NOC_RS01885
uniprot id: Q3JE87
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO large chain family. Type I subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterohexadecamer of 8 large chains and 8 small chains.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

323261:NOC RS03680
gene id: 323261:NOC_RS03680
uniprot id: Q3JDB0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

323261:NOC RS12190
gene id: 323261:NOC_RS12190
uniprot id: Q3J8V9
names: Similarity
messages: Belongs to the SfsA family.

323261:NOC RS13570
gene id: 323261:NOC_RS13570
uniprot id: Q3J843
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

323261:NOC RS13035
gene id: 323261:NOC_RS13035
uniprot id: Q3J8E9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

323261:NOC RS00395
gene id: 323261:NOC_RS00395
uniprot id: Q3JF17
names: Subcellular Location Annotation
messages: Mitochondrion

323261:NOC RS14035
gene id: 323261:NOC_RS14035
uniprot id: Q3J7V2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

323261:NOC RS16175
gene id: 323261:NOC_RS16175
uniprot id: Q3J6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

323261:NOC RS12435
gene id: 323261:NOC_RS12435
uniprot id: Q3J8Q9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

323261:NOC RS13285
gene id: 323261:NOC_RS13285
uniprot id: Q3J899
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

323261:NOC RS11020
gene id: 323261:NOC_RS11020
uniprot id: Q3J9H9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

323261:NOC RS06205
gene id: 323261:NOC_RS06205
uniprot id: Q3JC04
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS11175
gene id: 323261:NOC_RS11175
uniprot id: Q3J9E8
names: Similarity
messages: Belongs to the V-ATPase V0D/AC39 subunit family.

323261:NOC RS02040
gene id: 323261:NOC_RS02040
uniprot id: Q3JE57
names: Cofactor
names: Similarity
messages: Belongs to the PyrK family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 [2Fe-2S] cluster per subunit.

323261:NOC RS04935
gene id: 323261:NOC_RS04935
uniprot id: Q3JCM7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

323261:NOC RS11825
gene id: 323261:NOC_RS11825
uniprot id: Q3J921
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS00700
gene id: 323261:NOC_RS00700
uniprot id: Q3JEW3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

323261:NOC RS02085
gene id: 323261:NOC_RS02085
uniprot id: Q3JE48
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323261:NOC RS07555
gene id: 323261:NOC_RS07555
uniprot id: Q3JBA9
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

323261:NOC RS02780
gene id: 323261:NOC_RS02780
uniprot id: Q3JDS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

323261:NOC RS06950
gene id: 323261:NOC_RS06950
uniprot id: Q3JBM0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS11540
gene id: 323261:NOC_RS11540
uniprot id: Q3J978
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

323261:NOC RS01120
gene id: 323261:NOC_RS01120
uniprot id: Q3JEN3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

323261:NOC RS09035
gene id: 323261:NOC_RS09035
uniprot id: Q3JAK0
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

323261:NOC RS13370
gene id: 323261:NOC_RS13370
uniprot id: Q3J882
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323261:NOC RS12675
gene id: 323261:NOC_RS12675
uniprot id: Q3J8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

323261:NOC RS07305
gene id: 323261:NOC_RS07305
uniprot id: Q3JBF6
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

323261:NOC RS15890
gene id: 323261:NOC_RS15890
uniprot id: Q3J6V4
names: Similarity
messages: Belongs to the UPF0235 family.

323261:NOC RS03385
gene id: 323261:NOC_RS03385
uniprot id: Q3JDG3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

323261:NOC RS01375
gene id: 323261:NOC_RS01375
uniprot id: Q3JEI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

323261:NOC RS14120
gene id: 323261:NOC_RS14120
uniprot id: Q3J7T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

323261:NOC RS09585
gene id: 323261:NOC_RS09585
uniprot id: Q3JA98
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

323261:NOC RS09280
gene id: 323261:NOC_RS09280
uniprot id: Q3JAF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

323261:NOC RS08905
gene id: 323261:NOC_RS08905
uniprot id: Q3JAM5
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS06705
gene id: 323261:NOC_RS06705
uniprot id: Q3JBR7
names: Similarity
messages: Belongs to the ABC transporter superfamily.

323261:NOC RS01900
gene id: 323261:NOC_RS01900
uniprot id: Q3JE84
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

323261:NOC RS15765
gene id: 323261:NOC_RS15765
uniprot id: Q3J6X8
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

323261:NOC RS04260
gene id: 323261:NOC_RS04260
uniprot id: Q3JD06
names: Similarity
messages: Belongs to the asparagine synthetase family.

323261:NOC RS06615
gene id: 323261:NOC_RS06615
uniprot id: Q3JBT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

323261:NOC RS11675
gene id: 323261:NOC_RS11675
uniprot id: Q3J950
names: Similarity
messages: Belongs to the YkuD family.

323261:NOC RS16260
gene id: 323261:NOC_RS16260
uniprot id: Q3J6N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

323261:NOC RS12025
gene id: 323261:NOC_RS12025
uniprot id: Q3J8Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

323261:NOC RS10920
gene id: 323261:NOC_RS10920
uniprot id: Q3J9J9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

323261:NOC RS15715
gene id: 323261:NOC_RS15715
uniprot id: Q3J6Y8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

323261:NOC RS14875
gene id: 323261:NOC_RS14875
uniprot id: Q3J7E4
names: Similarity
messages: Belongs to the pyruvate kinase family.

323261:NOC RS12450
gene id: 323261:NOC_RS12450
uniprot id: Q3J8Q6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

323261:NOC RS02820
gene id: 323261:NOC_RS02820
uniprot id: Q3JDR4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

323261:NOC RS09240
gene id: 323261:NOC_RS09240
uniprot id: Q3JAG2
names: Similarity
messages: Belongs to the arginase family.

323261:NOC RS14855
gene id: 323261:NOC_RS14855
uniprot id: Q3J7E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323261:NOC RS04830
gene id: 323261:NOC_RS04830
uniprot id: Q3JCP7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

323261:NOC RS10735
gene id: 323261:NOC_RS10735
uniprot id: Q3J9N3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.

323261:NOC RS15065
gene id: 323261:NOC_RS15065
uniprot id: Q3J7A8
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

323261:NOC RS00880
gene id: 323261:NOC_RS00880
uniprot id: Q3JES8
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

323261:NOC RS14750
gene id: 323261:NOC_RS14750
uniprot id: Q3J7G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

323261:NOC RS11245
gene id: 323261:NOC_RS11245
uniprot id: Q3J9D5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

323261:NOC RS04825
gene id: 323261:NOC_RS04825
uniprot id: Q3JCP8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

323261:NOC RS13725
gene id: 323261:NOC_RS13725
uniprot id: Q3J814
names: Similarity
messages: Belongs to the peptidase M24B family.

323261:NOC RS02050
gene id: 323261:NOC_RS02050
uniprot id: Q3JE55
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

323261:NOC RS04610
gene id: 323261:NOC_RS04610
uniprot id: Q3JCT7
names: Subcellular Location Annotation
messages: Cytoplasm

323261:NOC RS09765
gene id: 323261:NOC_RS09765
uniprot id: Q3JA64
names: Similarity
messages: Belongs to the IucA/IucC family.

323261:NOC RS04405
gene id: 323261:NOC_RS04405
uniprot id: Q3JCX7
names: Activity Regulation
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

323261:NOC RS16080
gene id: 323261:NOC_RS16080
uniprot id: Q3J6R7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

323261:NOC RS03875
gene id: 323261:NOC_RS03875
uniprot id: Q3JD79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

323261:NOC RS05245
gene id: 323261:NOC_RS05245
uniprot id: Q3JCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0182 family.
messages: Cell membrane

323261:NOC RS05060
gene id: 323261:NOC_RS05060
uniprot id: Q3JCK8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

323261:NOC RS16055
gene id: 323261:NOC_RS16055
uniprot id: Q3J6S2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

323261:NOC RS04455
gene id: 323261:NOC_RS04455
uniprot id: Q3JCW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323261:NOC RS04265
gene id: 323261:NOC_RS04265
uniprot id: Q3JD05
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

323261:NOC RS00315
gene id: 323261:NOC_RS00315
uniprot id: Q3JF33
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

323261:NOC RS06235
gene id: 323261:NOC_RS06235
uniprot id: Q3JBZ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

323261:NOC RS16245
gene id: 323261:NOC_RS16245
uniprot id: Q3J6N4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS00945
gene id: 323261:NOC_RS00945
uniprot id: Q3JER5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS06700
gene id: 323261:NOC_RS06700
uniprot id: Q3JBR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323261:NOC RS04545
gene id: 323261:NOC_RS04545
uniprot id: Q3JCU9
names: Similarity
messages: Belongs to the MotB family.

323261:NOC RS13980
gene id: 323261:NOC_RS13980
uniprot id: Q3J7W3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

323261:NOC RS02655
gene id: 323261:NOC_RS02655
uniprot id: Q3JDU5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS01195
gene id: 323261:NOC_RS01195
uniprot id: Q3JEM0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323261:NOC RS04485
gene id: 323261:NOC_RS04485
uniprot id: Q3JCW1
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

323261:NOC RS00890
gene id: 323261:NOC_RS00890
uniprot id: Q3JES6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

323261:NOC RS02185
gene id: 323261:NOC_RS02185
uniprot id: Q3JE29
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323261:NOC RS13870
gene id: 323261:NOC_RS13870
uniprot id: Q3J7Y6
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

323261:NOC RS12540
gene id: 323261:NOC_RS12540
uniprot id: Q3J8P2
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS11275
gene id: 323261:NOC_RS11275
uniprot id: Q3J9C9
names: Similarity
messages: Belongs to the bacterial secretin family.

323261:NOC RS05725
gene id: 323261:NOC_RS05725
uniprot id: Q3JC86
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

323261:NOC RS01980
gene id: 323261:NOC_RS01980
uniprot id: Q3JE69
names: Similarity
messages: Belongs to the rubredoxin family.

323261:NOC RS12340
gene id: 323261:NOC_RS12340
uniprot id: Q3J8S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

323261:NOC RS15900
gene id: 323261:NOC_RS15900
uniprot id: Q3J6V2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

323261:NOC RS15930
gene id: 323261:NOC_RS15930
uniprot id: Q3J6U5
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

323261:NOC RS00310
gene id: 323261:NOC_RS00310
uniprot id: Q3JF34
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

323261:NOC RS15240
gene id: 323261:NOC_RS15240
uniprot id: Q3J773
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

323261:NOC RS04475
gene id: 323261:NOC_RS04475
uniprot id: Q3JCW3
names: Similarity
messages: Belongs to the YfgM family.

323261:NOC RS12295
gene id: 323261:NOC_RS12295
uniprot id: Q3J8T8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

323261:NOC RS14410
gene id: 323261:NOC_RS14410
uniprot id: Q3J7M9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

323261:NOC RS06335
gene id: 323261:NOC_RS06335
uniprot id: Q3JBY2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

323261:NOC RS02175
gene id: 323261:NOC_RS02175
uniprot id: Q3JE31
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is required both for tRNA processing and repair. Also involved in tRNA surveillance by mediating tandem CCA addition to generate a CCACCA at the 3' terminus of unstable tRNAs. While stable tRNAs receive only 3'-terminal CCA, unstable tRNAs are marked with CCACCA and rapidly degraded.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

323261:NOC RS15175
gene id: 323261:NOC_RS15175
uniprot id: Q3J786
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

323261:NOC RS12865
gene id: 323261:NOC_RS12865
uniprot id: Q3J8H9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323261:NOC RS13820
gene id: 323261:NOC_RS13820
uniprot id: Q3J7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

323261:NOC RS16150
gene id: 323261:NOC_RS16150
uniprot id: Q3J6Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

323261:NOC RS06970
gene id: 323261:NOC_RS06970
uniprot id: Q3JBL6
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12360
gene id: 323261:NOC_RS12360
uniprot id: Q3J8S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

323261:NOC RS13150
gene id: 323261:NOC_RS13150
uniprot id: Q3J8C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

323261:NOC RS14260
gene id: 323261:NOC_RS14260
uniprot id: Q3J7Q8
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

323261:NOC RS03355
gene id: 323261:NOC_RS03355
uniprot id: Q3JDG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

323261:NOC RS15135
gene id: 323261:NOC_RS15135
uniprot id: Q3J794
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

323261:NOC RS14445
gene id: 323261:NOC_RS14445
uniprot id: Q3J7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

323261:NOC RS13890
gene id: 323261:NOC_RS13890
uniprot id: Q3J7Y2
names: Similarity
messages: Belongs to the DEAD box helicase family.

323261:NOC RS03340
gene id: 323261:NOC_RS03340
uniprot id: Q3JDH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

323261:NOC RS04345
gene id: 323261:NOC_RS04345
uniprot id: Q3JCY9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

323261:NOC RS06415
gene id: 323261:NOC_RS06415
uniprot id: Q3JBW8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS15330
gene id: 323261:NOC_RS15330
uniprot id: Q3J754
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

323261:NOC RS11655
gene id: 323261:NOC_RS11655
uniprot id: Q3J954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS14935
gene id: 323261:NOC_RS14935
uniprot id: Q3J7D2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS10850
gene id: 323261:NOC_RS10850
uniprot id: Q3J9L2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

323261:NOC RS13825
gene id: 323261:NOC_RS13825
uniprot id: Q3J7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

323261:NOC RS15205
gene id: 323261:NOC_RS15205
uniprot id: Q3J780
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

323261:NOC RS12510
gene id: 323261:NOC_RS12510
uniprot id: Q3J8P8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

323261:NOC RS06585
gene id: 323261:NOC_RS06585
uniprot id: Q3JBT9
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

323261:NOC RS06930
gene id: 323261:NOC_RS06930
uniprot id: Q3JBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323261:NOC RS16110
gene id: 323261:NOC_RS16110
uniprot id: Q3J6R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

323261:NOC RS13685
gene id: 323261:NOC_RS13685
uniprot id: Q3J822
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

323261:NOC RS05945
gene id: 323261:NOC_RS05945
uniprot id: Q3JC48
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

323261:NOC RS14255
gene id: 323261:NOC_RS14255
uniprot id: Q3J7Q9
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

323261:NOC RS08135
gene id: 323261:NOC_RS08135
uniprot id: Q3JB03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

323261:NOC RS11785
gene id: 323261:NOC_RS11785
uniprot id: Q3J929
names: Similarity
messages: Belongs to the PrpD family.

323261:NOC RS04650
gene id: 323261:NOC_RS04650
uniprot id: Q3JCS9
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

323261:NOC RS01080
gene id: 323261:NOC_RS01080
uniprot id: Q3JEP1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS11305
gene id: 323261:NOC_RS11305
uniprot id: Q3J9C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

323261:NOC RS12330
gene id: 323261:NOC_RS12330
uniprot id: Q3J8T1
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

323261:NOC RS12690
gene id: 323261:NOC_RS12690
uniprot id: Q3J8L3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

323261:NOC RS04645
gene id: 323261:NOC_RS04645
uniprot id: Q3JCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323261:NOC RS14010
gene id: 323261:NOC_RS14010
uniprot id: Q3J7V7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

323261:NOC RS12475
gene id: 323261:NOC_RS12475
uniprot id: Q3J8Q1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS07545
gene id: 323261:NOC_RS07545
uniprot id: Q3JBB1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS10380
gene id: 323261:NOC_RS10380
uniprot id: Q3J9V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

323261:NOC RS01715
gene id: 323261:NOC_RS01715
uniprot id: Q3JEB9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

323261:NOC RS04560
gene id: 323261:NOC_RS04560
uniprot id: Q3JCU7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

323261:NOC RS01925
gene id: 323261:NOC_RS01925
uniprot id: Q3JE79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

323261:NOC RS13760
gene id: 323261:NOC_RS13760
uniprot id: Q3J807
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

323261:NOC RS15520
gene id: 323261:NOC_RS15520
uniprot id: Q3J720
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

323261:NOC RS09235
gene id: 323261:NOC_RS09235
uniprot id: Q3JAG3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS04950
gene id: 323261:NOC_RS04950
uniprot id: Q3JCM4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06565
gene id: 323261:NOC_RS06565
uniprot id: Q3JBU1
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

323261:NOC RS08885
gene id: 323261:NOC_RS08885
uniprot id: Q3JAM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

323261:NOC RS06845
gene id: 323261:NOC_RS06845
uniprot id: Q3JBP0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

323261:NOC RS11375
gene id: 323261:NOC_RS11375
uniprot id: Q3J9B0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

323261:NOC RS07860
gene id: 323261:NOC_RS07860
uniprot id: Q3JB52
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS00435
gene id: 323261:NOC_RS00435
uniprot id: Q3JF09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

323261:NOC RS16825
gene id: 323261:NOC_RS16825
uniprot id: Q3JB62
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

323261:NOC RS01425
gene id: 323261:NOC_RS01425
uniprot id: Q3JEH7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

323261:NOC RS05345
gene id: 323261:NOC_RS05345
uniprot id: Q3JCF8
names: Similarity
messages: Belongs to the MlaA family.

323261:NOC RS10355
gene id: 323261:NOC_RS10355
uniprot id: Q3J9V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS13435
gene id: 323261:NOC_RS13435
uniprot id: Q3J869
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

323261:NOC RS00915
gene id: 323261:NOC_RS00915
uniprot id: Q3JES1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323261:NOC RS04820
gene id: 323261:NOC_RS04820
uniprot id: Q3JCP9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

323261:NOC RS12575
gene id: 323261:NOC_RS12575
uniprot id: Q3J8N5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

323261:NOC RS03315
gene id: 323261:NOC_RS03315
uniprot id: Q3JDH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

323261:NOC RS04440
gene id: 323261:NOC_RS04440
uniprot id: Q3JCX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

323261:NOC RS14290
gene id: 323261:NOC_RS14290
uniprot id: Q3J7Q3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323261:NOC RS09630
gene id: 323261:NOC_RS09630
uniprot id: Q3JA90
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323261:NOC RS00760
gene id: 323261:NOC_RS00760
uniprot id: Q3JEV1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323261:NOC RS15365
gene id: 323261:NOC_RS15365
uniprot id: Q3J747
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS16060
gene id: 323261:NOC_RS16060
uniprot id: Q3J6S1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

323261:NOC RS05700
gene id: 323261:NOC_RS05700
uniprot id: Q3JC91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

323261:NOC RS02000
gene id: 323261:NOC_RS02000
uniprot id: Q3JE65
names: Similarity
messages: Belongs to the UPF0102 family.

323261:NOC RS13765
gene id: 323261:NOC_RS13765
uniprot id: Q3J806
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

323261:NOC RS04400
gene id: 323261:NOC_RS04400
uniprot id: Q3JCX8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

323261:NOC RS10245
gene id: 323261:NOC_RS10245
uniprot id: Q3J9X9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

323261:NOC RS12400
gene id: 323261:NOC_RS12400
uniprot id: Q3J8R6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

323261:NOC RS09615
gene id: 323261:NOC_RS09615
uniprot id: Q3JA92
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS10845
gene id: 323261:NOC_RS10845
uniprot id: Q3J9L3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

323261:NOC RS00385
gene id: 323261:NOC_RS00385
uniprot id: Q3JF19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

323261:NOC RS13410
gene id: 323261:NOC_RS13410
uniprot id: Q3J874
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

323261:NOC RS10160
gene id: 323261:NOC_RS10160
uniprot id: Q3J9Z1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

323261:NOC RS12415
gene id: 323261:NOC_RS12415
uniprot id: Q3J8R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

323261:NOC RS04660
gene id: 323261:NOC_RS04660
uniprot id: Q3JCS7
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

323261:NOC RS01025
gene id: 323261:NOC_RS01025
uniprot id: Q3JEP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

323261:NOC RS06535
gene id: 323261:NOC_RS06535
uniprot id: Q3JBU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

323261:NOC RS15315
gene id: 323261:NOC_RS15315
uniprot id: Q3J757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP G family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS15795
gene id: 323261:NOC_RS15795
uniprot id: Q3J6X2
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

323261:NOC RS09605
gene id: 323261:NOC_RS09605
uniprot id: Q3JA94
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323261:NOC RS08040
gene id: 323261:NOC_RS08040
uniprot id: Q3JB19
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

323261:NOC RS11230
gene id: 323261:NOC_RS11230
uniprot id: Q3J9D8
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

323261:NOC RS13785
gene id: 323261:NOC_RS13785
uniprot id: Q3J802
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

323261:NOC RS11280
gene id: 323261:NOC_RS11280
uniprot id: Q3J9C8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

323261:NOC RS02195
gene id: 323261:NOC_RS02195
uniprot id: Q3JE27
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

323261:NOC RS01960
gene id: 323261:NOC_RS01960
uniprot id: Q3JE73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

323261:NOC RS05415
gene id: 323261:NOC_RS05415
uniprot id: Q3JCE7
names: Similarity
messages: Belongs to the pyruvate kinase family.

323261:NOC RS05530
gene id: 323261:NOC_RS05530
uniprot id: Q3JCC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

323261:NOC RS00400
gene id: 323261:NOC_RS00400
uniprot id: Q3JF16
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

323261:NOC RS08160
gene id: 323261:NOC_RS08160
uniprot id: Q3JAZ8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12135
gene id: 323261:NOC_RS12135
uniprot id: Q3J8X0
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

323261:NOC RS04235
gene id: 323261:NOC_RS04235
uniprot id: Q3JD11
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS01740
gene id: 323261:NOC_RS01740
uniprot id: Q3JEB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 3 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

323261:NOC RS00920
gene id: 323261:NOC_RS00920
uniprot id: Q3JES0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323261:NOC RS06090
gene id: 323261:NOC_RS06090
uniprot id: Q3JC23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS09545
gene id: 323261:NOC_RS09545
uniprot id: Q3JAA4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14055
gene id: 323261:NOC_RS14055
uniprot id: Q3J7U8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13880
gene id: 323261:NOC_RS13880
uniprot id: Q3J7Y4
names: Subcellular Location Annotation
messages: Cytoplasm

323261:NOC RS04925
gene id: 323261:NOC_RS04925
uniprot id: Q3JCM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

323261:NOC RS14775
gene id: 323261:NOC_RS14775
uniprot id: Q3J7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

323261:NOC RS11565
gene id: 323261:NOC_RS11565
uniprot id: Q3J973
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

323261:NOC RS05055
gene id: 323261:NOC_RS05055
uniprot id: Q3JCK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

323261:NOC RS13405
gene id: 323261:NOC_RS13405
uniprot id: Q3J875
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

323261:NOC RS00950
gene id: 323261:NOC_RS00950
uniprot id: Q3JER4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

323261:NOC RS01230
gene id: 323261:NOC_RS01230
uniprot id: Q3JEL5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS08850
gene id: 323261:NOC_RS08850
uniprot id: Q3JAN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

323261:NOC RS11385
gene id: 323261:NOC_RS11385
uniprot id: Q3J9A8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS06840
gene id: 323261:NOC_RS06840
uniprot id: Q3JBP1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

323261:NOC RS08440
gene id: 323261:NOC_RS08440
uniprot id: Q3JAU8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

323261:NOC RS13710
gene id: 323261:NOC_RS13710
uniprot id: Q3J817
names: Function
names: Similarity
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Homodimer. Interacts with FtsZ.

323261:NOC RS14070
gene id: 323261:NOC_RS14070
uniprot id: Q3J7U5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

323261:NOC RS05050
gene id: 323261:NOC_RS05050
uniprot id: Q3JCL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS10505
gene id: 323261:NOC_RS10505
uniprot id: Q3J9S9
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06400
gene id: 323261:NOC_RS06400
uniprot id: Q3JBX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323261:NOC RS12585
gene id: 323261:NOC_RS12585
uniprot id: Q3J8N3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

323261:NOC RS05545
gene id: 323261:NOC_RS05545
uniprot id: Q3JCC2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS12885
gene id: 323261:NOC_RS12885
uniprot id: Q3J8H5
names: Cofactor
names: Similarity
messages: Belongs to the WrbA family.
messages: Binds 1 FMN per monomer.

323261:NOC RS11815
gene id: 323261:NOC_RS11815
uniprot id: Q3J923
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS15185
gene id: 323261:NOC_RS15185
uniprot id: Q3J784
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS14320
gene id: 323261:NOC_RS14320
uniprot id: Q3J7P5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS05995
gene id: 323261:NOC_RS05995
uniprot id: Q3JC41
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

323261:NOC RS14230
gene id: 323261:NOC_RS14230
uniprot id: Q3J7R4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

323261:NOC RS10325
gene id: 323261:NOC_RS10325
uniprot id: Q3J9W4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323261:NOC RS03070
gene id: 323261:NOC_RS03070
uniprot id: Q3JDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cytoplasm
messages: Homodimer or homotetramer.

323261:NOC RS16630
gene id: 323261:NOC_RS16630
uniprot id: Q3JDU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

323261:NOC RS01270
gene id: 323261:NOC_RS01270
uniprot id: Q3JEK8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

323261:NOC RS13425
gene id: 323261:NOC_RS13425
uniprot id: Q3J871
names: Similarity
messages: Belongs to the SAICAR synthetase family.

323261:NOC RS13730
gene id: 323261:NOC_RS13730
uniprot id: Q3J813
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

323261:NOC RS01530
gene id: 323261:NOC_RS01530
uniprot id: Q3JEF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

323261:NOC RS14435
gene id: 323261:NOC_RS14435
uniprot id: Q3J7M4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12410
gene id: 323261:NOC_RS12410
uniprot id: Q3J8R4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

323261:NOC RS14280
gene id: 323261:NOC_RS14280
uniprot id: Q3J7Q5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

323261:NOC RS15660
gene id: 323261:NOC_RS15660
uniprot id: Q3J6Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

323261:NOC RS11155
gene id: 323261:NOC_RS11155
uniprot id: Q3J9F2
names: Function
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

323261:NOC RS12310
gene id: 323261:NOC_RS12310
uniprot id: Q3J8T5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

323261:NOC RS15875
gene id: 323261:NOC_RS15875
uniprot id: Q3J6V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323261:NOC RS04270
gene id: 323261:NOC_RS04270
uniprot id: Q3JD04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

323261:NOC RS04510
gene id: 323261:NOC_RS04510
uniprot id: Q3JCV6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

323261:NOC RS11570
gene id: 323261:NOC_RS11570
uniprot id: Q3J972
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliN/MopA/SpaO family.
messages: Cell membrane
messages: FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323261:NOC RS14790
gene id: 323261:NOC_RS14790
uniprot id: Q3J7G1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

323261:NOC RS01155
gene id: 323261:NOC_RS01155
uniprot id: Q3JEM7
names: Similarity
messages: Belongs to the ArsC family.

323261:NOC RS11830
gene id: 323261:NOC_RS11830
uniprot id: Q3J920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323261:NOC RS05015
gene id: 323261:NOC_RS05015
uniprot id: Q3JCL7
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

323261:NOC RS01075
gene id: 323261:NOC_RS01075
uniprot id: Q3JEP2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

323261:NOC RS10300
gene id: 323261:NOC_RS10300
uniprot id: Q3J9W8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

323261:NOC RS04915
gene id: 323261:NOC_RS04915
uniprot id: Q3JCN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

323261:NOC RS13645
gene id: 323261:NOC_RS13645
uniprot id: Q3J828
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS15640
gene id: 323261:NOC_RS15640
uniprot id: Q3J700
names: Similarity
messages: Belongs to the universal stress protein A family.

323261:NOC RS13515
gene id: 323261:NOC_RS13515
uniprot id: Q3J853
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

323261:NOC RS15110
gene id: 323261:NOC_RS15110
uniprot id: Q3J799
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: May bind 1 zinc ion per subunit.
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

323261:NOC RS03280
gene id: 323261:NOC_RS03280
uniprot id: Q3JDI2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06640
gene id: 323261:NOC_RS06640
uniprot id: Q3JBS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

323261:NOC RS02470
gene id: 323261:NOC_RS02470
uniprot id: Q3JDY0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

323261:NOC RS13145
gene id: 323261:NOC_RS13145
uniprot id: Q3J8C7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323261:NOC RS04525
gene id: 323261:NOC_RS04525
uniprot id: Q3JCV3
names: Similarity
messages: Belongs to the aminoglycoside phosphotransferase family.
messages: Belongs to the glycosyl hydrolase 13 family. TreS subfamily.

323261:NOC RS14030
gene id: 323261:NOC_RS14030
uniprot id: Q3J7V3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

323261:NOC RS16250
gene id: 323261:NOC_RS16250
uniprot id: Q3J6N3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

323261:NOC RS05720
gene id: 323261:NOC_RS05720
uniprot id: Q3JC87
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

323261:NOC RS01060
gene id: 323261:NOC_RS01060
uniprot id: Q3JEP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS01090
gene id: 323261:NOC_RS01090
uniprot id: Q3JEN9
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

323261:NOC RS03685
gene id: 323261:NOC_RS03685
uniprot id: Q3JDA9
names: Similarity
messages: Belongs to the AAA ATPase family.

323261:NOC RS12250
gene id: 323261:NOC_RS12250
uniprot id: Q3J8U8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

323261:NOC RS13970
gene id: 323261:NOC_RS13970
uniprot id: Q3J7W5
names: Similarity
messages: Belongs to the citrate synthase family.

323261:NOC RS03375
gene id: 323261:NOC_RS03375
uniprot id: Q3JDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

323261:NOC RS09290
gene id: 323261:NOC_RS09290
uniprot id: Q3JAF2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

323261:NOC RS16185
gene id: 323261:NOC_RS16185
uniprot id: Q3J6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323261:NOC RS15255
gene id: 323261:NOC_RS15255
uniprot id: Q3J770
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

323261:NOC RS14125
gene id: 323261:NOC_RS14125
uniprot id: Q3J7T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

323261:NOC RS15035
gene id: 323261:NOC_RS15035
uniprot id: Q3J7B3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

323261:NOC RS01370
gene id: 323261:NOC_RS01370
uniprot id: Q3JEI8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323261:NOC RS01945
gene id: 323261:NOC_RS01945
uniprot id: Q3JE76
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS06945
gene id: 323261:NOC_RS06945
uniprot id: Q3JBM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell outer membrane

323261:NOC RS02055
gene id: 323261:NOC_RS02055
uniprot id: Q3JE54
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

323261:NOC RS15335
gene id: 323261:NOC_RS15335
uniprot id: Q3J753
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

323261:NOC RS05560
gene id: 323261:NOC_RS05560
uniprot id: Q3JCB9
names: Similarity
messages: Belongs to the TrpF family.

323261:NOC RS00085
gene id: 323261:NOC_RS00085
uniprot id: Q3JF69
names: Similarity
messages: Belongs to the ParB family.

323261:NOC RS11535
gene id: 323261:NOC_RS11535
uniprot id: Q3J979
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

323261:NOC RS05715
gene id: 323261:NOC_RS05715
uniprot id: Q3JC88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

323261:NOC RS08390
gene id: 323261:NOC_RS08390
uniprot id: Q3JAV3
names: Function
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.

323261:NOC RS00755
gene id: 323261:NOC_RS00755
uniprot id: Q3JEV2
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

323261:NOC RS08315
gene id: 323261:NOC_RS08315
uniprot id: Q3JAW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

323261:NOC RS14740
gene id: 323261:NOC_RS14740
uniprot id: Q3J7H1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

323261:NOC RS03305
gene id: 323261:NOC_RS03305
uniprot id: Q3JDH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS15080
gene id: 323261:NOC_RS15080
uniprot id: Q3J7A5
names: Similarity
messages: Belongs to the peptidase S49 family.

323261:NOC RS13415
gene id: 323261:NOC_RS13415
uniprot id: Q3J873
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

323261:NOC RS07525
gene id: 323261:NOC_RS07525
uniprot id: Q3JBB5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323261:NOC RS00935
gene id: 323261:NOC_RS00935
uniprot id: Q3JER7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Cell outer membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323261:NOC RS00375
gene id: 323261:NOC_RS00375
uniprot id: Q3JF21
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

323261:NOC RS12285
gene id: 323261:NOC_RS12285
uniprot id: Q3J8U0
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

323261:NOC RS04420
gene id: 323261:NOC_RS04420
uniprot id: Q3JCX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

323261:NOC RS07285
gene id: 323261:NOC_RS07285
uniprot id: Q3JBG0
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

323261:NOC RS14415
gene id: 323261:NOC_RS14415
uniprot id: Q3J7M8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS05300
gene id: 323261:NOC_RS05300
uniprot id: Q3JCG5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

323261:NOC RS08235
gene id: 323261:NOC_RS08235
uniprot id: Q3JAY2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS11335
gene id: 323261:NOC_RS11335
uniprot id: Q3J9B7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

323261:NOC RS15130
gene id: 323261:NOC_RS15130
uniprot id: Q3J795
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

323261:NOC RS13605
gene id: 323261:NOC_RS13605
uniprot id: Q3J836
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS11790
gene id: 323261:NOC_RS11790
uniprot id: Q3J928
names: Similarity
messages: Belongs to the citrate synthase family.

323261:NOC RS02805
gene id: 323261:NOC_RS02805
uniprot id: Q3JDR7
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

323261:NOC RS09725
gene id: 323261:NOC_RS09725
uniprot id: Q3JA72
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

323261:NOC RS08915
gene id: 323261:NOC_RS08915
uniprot id: Q3JAM3
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS05910
gene id: 323261:NOC_RS05910
uniprot id: Q3JC55
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323261:NOC RS13380
gene id: 323261:NOC_RS13380
uniprot id: Q3J880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

323261:NOC RS02625
gene id: 323261:NOC_RS02625
uniprot id: Q3JDV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323261:NOC RS00365
gene id: 323261:NOC_RS00365
uniprot id: Q3JF23
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

323261:NOC RS15850
gene id: 323261:NOC_RS15850
uniprot id: Q3J6W2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS09895
gene id: 323261:NOC_RS09895
uniprot id: Q3JA41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

323261:NOC RS13235
gene id: 323261:NOC_RS13235
uniprot id: Q3J8A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RfaH family.
messages: Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components.
messages: Interacts with both the nontemplate DNA and the RNA polymerase (RNAP).

323261:NOC RS12895
gene id: 323261:NOC_RS12895
uniprot id: Q3J8H4
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

323261:NOC RS15865
gene id: 323261:NOC_RS15865
uniprot id: Q3J6V9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

323261:NOC RS15145
gene id: 323261:NOC_RS15145
uniprot id: Q3J792
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

323261:NOC RS05100
gene id: 323261:NOC_RS05100
uniprot id: Q3JCK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

323261:NOC RS06690
gene id: 323261:NOC_RS06690
uniprot id: Q3JBS0
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

323261:NOC RS09915
gene id: 323261:NOC_RS09915
uniprot id: Q3JA37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

323261:NOC RS10385
gene id: 323261:NOC_RS10385
uniprot id: Q3J9V3
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmD family.
messages: Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle.

323261:NOC RS05650
gene id: 323261:NOC_RS05650
uniprot id: Q3JCA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

323261:NOC RS14720
gene id: 323261:NOC_RS14720
uniprot id: Q3J7H5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

323261:NOC RS12945
gene id: 323261:NOC_RS12945
uniprot id: Q3J8G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

323261:NOC RS07405
gene id: 323261:NOC_RS07405
uniprot id: Q3JBD7
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS04450
gene id: 323261:NOC_RS04450
uniprot id: Q3JCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

323261:NOC RS14040
gene id: 323261:NOC_RS14040
uniprot id: Q3J7V1
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13275
gene id: 323261:NOC_RS13275
uniprot id: Q3J8A1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

323261:NOC RS13860
gene id: 323261:NOC_RS13860
uniprot id: Q3J7Y8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323261:NOC RS11800
gene id: 323261:NOC_RS11800
uniprot id: Q3J926
names: Similarity
messages: Belongs to the universal stress protein A family.

323261:NOC RS01630
gene id: 323261:NOC_RS01630
uniprot id: Q3JED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323261:NOC RS09355
gene id: 323261:NOC_RS09355
uniprot id: Q3JAE1
names: Similarity
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

323261:NOC RS08550
gene id: 323261:NOC_RS08550
uniprot id: Q3JAT0
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

323261:NOC RS06220
gene id: 323261:NOC_RS06220
uniprot id: Q3JC02
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS16155
gene id: 323261:NOC_RS16155
uniprot id: Q3J6Q3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

323261:NOC RS06475
gene id: 323261:NOC_RS06475
uniprot id: Q3JBV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

323261:NOC RS01415
gene id: 323261:NOC_RS01415
uniprot id: Q3JEH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS09440
gene id: 323261:NOC_RS09440
uniprot id: Q3JAC5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

323261:NOC RS04710
gene id: 323261:NOC_RS04710
uniprot id: Q3JCR8
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

323261:NOC RS12670
gene id: 323261:NOC_RS12670
uniprot id: Q3J8L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

323261:NOC RS04900
gene id: 323261:NOC_RS04900
uniprot id: Q3JCN4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

323261:NOC RS09270
gene id: 323261:NOC_RS09270
uniprot id: Q3JAF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Molecular chaperone. Has ATPase activity.

323261:NOC RS10270
gene id: 323261:NOC_RS10270
uniprot id: Q3J9X4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS01760
gene id: 323261:NOC_RS01760
uniprot id: Q3JEB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

323261:NOC RS01410
gene id: 323261:NOC_RS01410
uniprot id: Q3JEI0
names: Similarity
messages: Belongs to the UPF0758 family.

323261:NOC RS16290
gene id: 323261:NOC_RS16290
uniprot id: Q3J6M5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

323261:NOC RS01435
gene id: 323261:NOC_RS01435
uniprot id: Q3JEH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS09045
gene id: 323261:NOC_RS09045
uniprot id: Q3JAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

323261:NOC RS07625
gene id: 323261:NOC_RS07625
uniprot id: Q3JB98
names: Similarity
messages: Belongs to the universal stress protein A family.

323261:NOC RS14285
gene id: 323261:NOC_RS14285
uniprot id: Q3J7Q4
names: Similarity
messages: Belongs to the HsdR family.

323261:NOC RS09040
gene id: 323261:NOC_RS09040
uniprot id: Q3JAJ9
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

323261:NOC RS15195
gene id: 323261:NOC_RS15195
uniprot id: Q3J782
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323261:NOC RS01190
gene id: 323261:NOC_RS01190
uniprot id: Q3JEM1
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

323261:NOC RS15990
gene id: 323261:NOC_RS15990
uniprot id: Q3J6T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

323261:NOC RS13755
gene id: 323261:NOC_RS13755
uniprot id: Q3J808
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

323261:NOC RS00655
gene id: 323261:NOC_RS00655
uniprot id: Q3JEX2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multicopper oxidase family.
messages: Binds 1 Cu(+) ion.
messages: Homotrimer.
messages: Periplasm

323261:NOC RS07620
gene id: 323261:NOC_RS07620
uniprot id: Q3JB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323261:NOC RS12650
gene id: 323261:NOC_RS12650
uniprot id: Q3J8M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

323261:NOC RS12695
gene id: 323261:NOC_RS12695
uniprot id: Q3J8L2
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

323261:NOC RS14895
gene id: 323261:NOC_RS14895
uniprot id: Q3J7E0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

323261:NOC RS06490
gene id: 323261:NOC_RS06490
uniprot id: Q3JBV5
names: Similarity
messages: Belongs to the RecJ family.

323261:NOC RS03925
gene id: 323261:NOC_RS03925
uniprot id: Q3JD69
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

323261:NOC RS02500
gene id: 323261:NOC_RS02500
uniprot id: Q3JDX4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

323261:NOC RS14095
gene id: 323261:NOC_RS14095
uniprot id: Q3J7U0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

323261:NOC RS11150
gene id: 323261:NOC_RS11150
uniprot id: Q3J9F3
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

323261:NOC RS06620
gene id: 323261:NOC_RS06620
uniprot id: Q3JBT2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323261:NOC RS11315
gene id: 323261:NOC_RS11315
uniprot id: Q3J9C1
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

323261:NOC RS11430
gene id: 323261:NOC_RS11430
uniprot id: Q3J9A0
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS04640
gene id: 323261:NOC_RS04640
uniprot id: Q3JCT1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

323261:NOC RS15160
gene id: 323261:NOC_RS15160
uniprot id: Q3J789
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

323261:NOC RS11440
gene id: 323261:NOC_RS11440
uniprot id: Q3J998
names: Similarity
messages: Belongs to the UPF0045 family.

323261:NOC RS12815
gene id: 323261:NOC_RS12815
uniprot id: Q3J8I9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.
messages: Periplasm
messages: Secreted

323261:NOC RS01160
gene id: 323261:NOC_RS01160
uniprot id: Q3JEM6
names: Similarity
messages: Belongs to the WrbA family.

323261:NOC RS12460
gene id: 323261:NOC_RS12460
uniprot id: Q3J8Q4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

323261:NOC RS01150
gene id: 323261:NOC_RS01150
uniprot id: Q3JEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

323261:NOC RS01915
gene id: 323261:NOC_RS01915
uniprot id: Q3JE81
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS06310
gene id: 323261:NOC_RS06310
uniprot id: Q3JBY6
names: Similarity
messages: Belongs to the peptidase S9C family.

323261:NOC RS02465
gene id: 323261:NOC_RS02465
uniprot id: Q3JDY1
names: Similarity
messages: Belongs to the VapB family.

323261:NOC RS06555
gene id: 323261:NOC_RS06555
uniprot id: Q3JBU3
names: Similarity
messages: Belongs to the HepT RNase toxin family.

323261:NOC RS07125
gene id: 323261:NOC_RS07125
uniprot id: Q3JBI8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

323261:NOC RS02435
gene id: 323261:NOC_RS02435
uniprot id: Q3JDY7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

323261:NOC RS13960
gene id: 323261:NOC_RS13960
uniprot id: Q3J7W7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

323261:NOC RS15370
gene id: 323261:NOC_RS15370
uniprot id: Q3J746
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

323261:NOC RS15560
gene id: 323261:NOC_RS15560
uniprot id: Q3J713
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

323261:NOC RS08675
gene id: 323261:NOC_RS08675
uniprot id: Q3JAR3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

323261:NOC RS12355
gene id: 323261:NOC_RS12355
uniprot id: Q3J8S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

323261:NOC RS13640
gene id: 323261:NOC_RS13640
uniprot id: Q3J829
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).

323261:NOC RS15310
gene id: 323261:NOC_RS15310
uniprot id: Q3J758
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS04355
gene id: 323261:NOC_RS04355
uniprot id: Q3JCY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

323261:NOC RS13190
gene id: 323261:NOC_RS13190
uniprot id: Q3J8B8
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

323261:NOC RS02670
gene id: 323261:NOC_RS02670
uniprot id: Q3JDU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS09285
gene id: 323261:NOC_RS09285
uniprot id: Q3JAF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

323261:NOC RS12920
gene id: 323261:NOC_RS12920
uniprot id: Q3J8G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

323261:NOC RS12245
gene id: 323261:NOC_RS12245
uniprot id: Q3J8U9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

323261:NOC RS14155
gene id: 323261:NOC_RS14155
uniprot id: Q3J7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

323261:NOC RS07280
gene id: 323261:NOC_RS07280
uniprot id: Q3JBG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323261:NOC RS14675
gene id: 323261:NOC_RS14675
uniprot id: Q3J7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

323261:NOC RS18390
gene id: 323261:NOC_RS18390
uniprot id: Q3JAP0
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14940
gene id: 323261:NOC_RS14940
uniprot id: Q3J7D1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

323261:NOC RS12050
gene id: 323261:NOC_RS12050
uniprot id: Q3J8Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323261:NOC RS09120
gene id: 323261:NOC_RS09120
uniprot id: Q3JAI7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

323261:NOC RS03940
gene id: 323261:NOC_RS03940
uniprot id: Q3JD66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

323261:NOC RS09775
gene id: 323261:NOC_RS09775
uniprot id: Q3JA62
names: Similarity
messages: Belongs to the IucA/IucC family.

323261:NOC RS10170
gene id: 323261:NOC_RS10170
uniprot id: Q3J9Y9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

323261:NOC RS06390
gene id: 323261:NOC_RS06390
uniprot id: Q3JBX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323261:NOC RS00740
gene id: 323261:NOC_RS00740
uniprot id: Q3JEV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

323261:NOC RS06530
gene id: 323261:NOC_RS06530
uniprot id: Q3JBU7
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

323261:NOC RS13695
gene id: 323261:NOC_RS13695
uniprot id: Q3J820
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

323261:NOC RS15190
gene id: 323261:NOC_RS15190
uniprot id: Q3J783
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

323261:NOC RS04835
gene id: 323261:NOC_RS04835
uniprot id: Q3JCP6
names: Similarity
messages: Belongs to the acylphosphatase family.

323261:NOC RS08360
gene id: 323261:NOC_RS08360
uniprot id: Q3JAV8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

323261:NOC RS07535
gene id: 323261:NOC_RS07535
uniprot id: Q3JBB3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

323261:NOC RS12060
gene id: 323261:NOC_RS12060
uniprot id: Q3J8Y4
names: Similarity
messages: Belongs to the UPF0234 family.

323261:NOC RS15055
gene id: 323261:NOC_RS15055
uniprot id: Q3J7B0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

323261:NOC RS12300
gene id: 323261:NOC_RS12300
uniprot id: Q3J8T7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

323261:NOC RS15075
gene id: 323261:NOC_RS15075
uniprot id: Q3J7A6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

323261:NOC RS11270
gene id: 323261:NOC_RS11270
uniprot id: Q3J9D0
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

323261:NOC RS04250
gene id: 323261:NOC_RS04250
uniprot id: Q3JD08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

323261:NOC RS12255
gene id: 323261:NOC_RS12255
uniprot id: Q3J8U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

323261:NOC RS09320
gene id: 323261:NOC_RS09320
uniprot id: Q3JAE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

323261:NOC RS03915
gene id: 323261:NOC_RS03915
uniprot id: Q3JD71
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS12080
gene id: 323261:NOC_RS12080
uniprot id: Q3J8Y1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

323261:NOC RS16285
gene id: 323261:NOC_RS16285
uniprot id: Q3J6M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.

323261:NOC RS01535
gene id: 323261:NOC_RS01535
uniprot id: Q3JEF4
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

323261:NOC RS04625
gene id: 323261:NOC_RS04625
uniprot id: Q3JCT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

323261:NOC RS01755
gene id: 323261:NOC_RS01755
uniprot id: Q3JEB2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323261:NOC RS11885
gene id: 323261:NOC_RS11885
uniprot id: Q3J910
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

323261:NOC RS07750
gene id: 323261:NOC_RS07750
uniprot id: Q3JB74
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

323261:NOC RS10605
gene id: 323261:NOC_RS10605
uniprot id: Q3J9Q9
names: Similarity
messages: Belongs to the asparagine synthetase family.

323261:NOC RS06085
gene id: 323261:NOC_RS06085
uniprot id: Q3JC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS14880
gene id: 323261:NOC_RS14880
uniprot id: Q3J7E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS04380
gene id: 323261:NOC_RS04380
uniprot id: Q3JCY2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

323261:NOC RS00410
gene id: 323261:NOC_RS00410
uniprot id: Q3JF14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

323261:NOC RS14215
gene id: 323261:NOC_RS14215
uniprot id: Q3J7R6
names: Similarity
messages: Belongs to the UPF0434 family.

323261:NOC RS09385
gene id: 323261:NOC_RS09385
uniprot id: Q3JAD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

323261:NOC RS08070
gene id: 323261:NOC_RS08070
uniprot id: Q3JB13
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14915
gene id: 323261:NOC_RS14915
uniprot id: Q3J7D6
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

323261:NOC RS04630
gene id: 323261:NOC_RS04630
uniprot id: Q3JCT3
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.

323261:NOC RS15690
gene id: 323261:NOC_RS15690
uniprot id: Q3J6Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

323261:NOC RS02065
gene id: 323261:NOC_RS02065
uniprot id: Q3JE52
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

323261:NOC RS11560
gene id: 323261:NOC_RS11560
uniprot id: Q3J974
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

323261:NOC RS14885
gene id: 323261:NOC_RS14885
uniprot id: Q3J7E2
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

323261:NOC RS06790
gene id: 323261:NOC_RS06790
uniprot id: Q3JBQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

323261:NOC RS12560
gene id: 323261:NOC_RS12560
uniprot id: Q3J8N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

323261:NOC RS01955
gene id: 323261:NOC_RS01955
uniprot id: Q3JE74
names: Similarity
messages: Belongs to the AlaDH/PNT family.

323261:NOC RS01890
gene id: 323261:NOC_RS01890
uniprot id: Q3JE86
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323261:NOC RS11525
gene id: 323261:NOC_RS11525
uniprot id: Q3J981
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

323261:NOC RS04855
gene id: 323261:NOC_RS04855
uniprot id: Q3JCP3
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS07550
gene id: 323261:NOC_RS07550
uniprot id: Q3JBB0
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

323261:NOC RS01420
gene id: 323261:NOC_RS01420
uniprot id: Q3JEH8
names: Similarity
messages: Belongs to the PhoH family.

323261:NOC RS11215
gene id: 323261:NOC_RS11215
uniprot id: Q3J9E1
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

323261:NOC RS12175
gene id: 323261:NOC_RS12175
uniprot id: Q3J8W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

323261:NOC RS15905
gene id: 323261:NOC_RS15905
uniprot id: Q3J6V1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

323261:NOC RS13865
gene id: 323261:NOC_RS13865
uniprot id: Q3J7Y7
names: Subunit
messages: Homotetramer.

323261:NOC RS15895
gene id: 323261:NOC_RS15895
uniprot id: Q3J6V3
names: Similarity
messages: Belongs to the YggT family.

323261:NOC RS15005
gene id: 323261:NOC_RS15005
uniprot id: Q3J7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

323261:NOC RS11225
gene id: 323261:NOC_RS11225
uniprot id: Q3J9D9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS01720
gene id: 323261:NOC_RS01720
uniprot id: Q3JEB8
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

323261:NOC RS11135
gene id: 323261:NOC_RS11135
uniprot id: Q3J9F6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

323261:NOC RS11555
gene id: 323261:NOC_RS11555
uniprot id: Q3J975
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

323261:NOC RS12335
gene id: 323261:NOC_RS12335
uniprot id: Q3J8T0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

323261:NOC RS11235
gene id: 323261:NOC_RS11235
uniprot id: Q3J9D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
messages: Cytoplasm
messages: Monomer.
messages: The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.

323261:NOC RS09540
gene id: 323261:NOC_RS09540
uniprot id: Q3JAA5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

323261:NOC RS12795
gene id: 323261:NOC_RS12795
uniprot id: Q3J8J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

323261:NOC RS08970
gene id: 323261:NOC_RS08970
uniprot id: Q3JAL3
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

323261:NOC RS04390
gene id: 323261:NOC_RS04390
uniprot id: Q3JCY0
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

323261:NOC RS01545
gene id: 323261:NOC_RS01545
uniprot id: Q3JEF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

323261:NOC RS13250
gene id: 323261:NOC_RS13250
uniprot id: Q3J8A6
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

323261:NOC RS08295
gene id: 323261:NOC_RS08295
uniprot id: Q3JAX1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323261:NOC RS15250
gene id: 323261:NOC_RS15250
uniprot id: Q3J771
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UreE family.
messages: Cytoplasm
messages: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.

323261:NOC RS13810
gene id: 323261:NOC_RS13810
uniprot id: Q3J7Z8
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

323261:NOC RS10915
gene id: 323261:NOC_RS10915
uniprot id: Q3J9K0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

323261:NOC RS06900
gene id: 323261:NOC_RS06900
uniprot id: Q3JBM9
names: Similarity
messages: Belongs to the TPP enzyme family.

323261:NOC RS14985
gene id: 323261:NOC_RS14985
uniprot id: Q3J7C2
names: Similarity
messages: Belongs to the GARS family.

323261:NOC RS02110
gene id: 323261:NOC_RS02110
uniprot id: Q3JE43
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane

323261:NOC RS09925
gene id: 323261:NOC_RS09925
uniprot id: Q3JA35
names: Similarity
messages: Belongs to the peptidase S1 family.

323261:NOC RS07475
gene id: 323261:NOC_RS07475
uniprot id: Q3JBC4
names: Cofactor
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

323261:NOC RS01515
gene id: 323261:NOC_RS01515
uniprot id: Q3JEF8
names: Similarity
messages: Belongs to the HisA/HisF family.

323261:NOC RS12800
gene id: 323261:NOC_RS12800
uniprot id: Q3J8J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

323261:NOC RS12065
gene id: 323261:NOC_RS12065
uniprot id: Q3J8Y3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

323261:NOC RS06440
gene id: 323261:NOC_RS06440
uniprot id: Q3JBW4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.

323261:NOC RS12545
gene id: 323261:NOC_RS12545
uniprot id: Q3J8P1
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

323261:NOC RS04255
gene id: 323261:NOC_RS04255
uniprot id: Q3JD07
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

323261:NOC RS02455
gene id: 323261:NOC_RS02455
uniprot id: Q3JDY3
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS09650
gene id: 323261:NOC_RS09650
uniprot id: Q3JA86
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

323261:NOC RS15945
gene id: 323261:NOC_RS15945
uniprot id: Q3J6U2
names: Similarity
messages: Belongs to the DprA/Smf family.

323261:NOC RS12605
gene id: 323261:NOC_RS12605
uniprot id: Q3J8M9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.

323261:NOC RS06625
gene id: 323261:NOC_RS06625
uniprot id: Q3JBT1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

323261:NOC RS13680
gene id: 323261:NOC_RS13680
uniprot id: Q3J823
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

323261:NOC RS16085
gene id: 323261:NOC_RS16085
uniprot id: Q3J6R6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.

323261:NOC RS05555
gene id: 323261:NOC_RS05555
uniprot id: Q3JCC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

323261:NOC RS04220
gene id: 323261:NOC_RS04220
uniprot id: Q3JD14
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

323261:NOC RS12395
gene id: 323261:NOC_RS12395
uniprot id: Q3J8R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

323261:NOC RS02620
gene id: 323261:NOC_RS02620
uniprot id: Q3JDV2
names: Similarity
messages: Belongs to the TPP enzyme family.

323261:NOC RS15460
gene id: 323261:NOC_RS15460
uniprot id: Q3J728
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

323261:NOC RS02575
gene id: 323261:NOC_RS02575
uniprot id: Q3JDW1
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS07010
gene id: 323261:NOC_RS07010
uniprot id: Q3JBK8
names: Similarity
messages: Belongs to the universal stress protein A family.

323261:NOC RS03320
gene id: 323261:NOC_RS03320
uniprot id: Q3JDH4
names: Similarity
messages: Belongs to the thioredoxin family.

323261:NOC RS10155
gene id: 323261:NOC_RS10155
uniprot id: Q3J9Z2
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

323261:NOC RS11670
gene id: 323261:NOC_RS11670
uniprot id: Q3J951
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

323261:NOC RS15570
gene id: 323261:NOC_RS15570
uniprot id: Q3J711
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13280
gene id: 323261:NOC_RS13280
uniprot id: Q3J8A0
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

323261:NOC RS00885
gene id: 323261:NOC_RS00885
uniprot id: Q3JES7
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS00120
gene id: 323261:NOC_RS00120
uniprot id: Q3JF62
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

323261:NOC RS08910
gene id: 323261:NOC_RS08910
uniprot id: Q3JAM4
names: Similarity
messages: Belongs to the HesB/IscA family.

323261:NOC RS05170
gene id: 323261:NOC_RS05170
uniprot id: Q3JCI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

323261:NOC RS13295
gene id: 323261:NOC_RS13295
uniprot id: Q3J897
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.

323261:NOC RS13975
gene id: 323261:NOC_RS13975
uniprot id: Q3J7W4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

323261:NOC RS14325
gene id: 323261:NOC_RS14325
uniprot id: Q3J7P4
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

323261:NOC RS08260
gene id: 323261:NOC_RS08260
uniprot id: Q3JAX8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS11370
gene id: 323261:NOC_RS11370
uniprot id: Q3J9B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

323261:NOC RS06850
gene id: 323261:NOC_RS06850
uniprot id: Q3JBN9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

323261:NOC RS14865
gene id: 323261:NOC_RS14865
uniprot id: Q3J7E6
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS16065
gene id: 323261:NOC_RS16065
uniprot id: Q3J6S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS10405
gene id: 323261:NOC_RS10405
uniprot id: Q3J9U9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

323261:NOC RS13735
gene id: 323261:NOC_RS13735
uniprot id: Q3J812
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

323261:NOC RS04240
gene id: 323261:NOC_RS04240
uniprot id: Q3JD10
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

323261:NOC RS04595
gene id: 323261:NOC_RS04595
uniprot id: Q3JCU0
names: Similarity
messages: Belongs to the peptidase S49 family.

323261:NOC RS16970
gene id: 323261:NOC_RS16970
uniprot id: Q3J8T4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

323261:NOC RS14160
gene id: 323261:NOC_RS14160
uniprot id: Q3J7S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

323261:NOC RS05145
gene id: 323261:NOC_RS05145
uniprot id: Q3JCJ3
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

323261:NOC RS10680
gene id: 323261:NOC_RS10680
uniprot id: Q3J9P3
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

323261:NOC RS00415
gene id: 323261:NOC_RS00415
uniprot id: Q3JF13
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

323261:NOC RS08630
gene id: 323261:NOC_RS08630
uniprot id: Q3JAS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323261:NOC RS01365
gene id: 323261:NOC_RS01365
uniprot id: Q3JEI9
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12655
gene id: 323261:NOC_RS12655
uniprot id: Q3J8M0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Secreted

323261:NOC RS04445
gene id: 323261:NOC_RS04445
uniprot id: Q3JCW9
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

323261:NOC RS14180
gene id: 323261:NOC_RS14180
uniprot id: Q3J7S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

323261:NOC RS11715
gene id: 323261:NOC_RS11715
uniprot id: Q3J942
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

323261:NOC RS14145
gene id: 323261:NOC_RS14145
uniprot id: Q3J7T0
names: Similarity
messages: Belongs to the DNA polymerase HolA subunit family.

323261:NOC RS07155
gene id: 323261:NOC_RS07155
uniprot id: Q3JBI4
names: Similarity
messages: Belongs to the peptidase M1 family.

323261:NOC RS07415
gene id: 323261:NOC_RS07415
uniprot id: Q3JBD6
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

323261:NOC RS13260
gene id: 323261:NOC_RS13260
uniprot id: Q3J8A4
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

323261:NOC RS10895
gene id: 323261:NOC_RS10895
uniprot id: Q3J9K4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

323261:NOC RS02775
gene id: 323261:NOC_RS02775
uniprot id: Q3JDS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

323261:NOC RS01170
gene id: 323261:NOC_RS01170
uniprot id: Q3JEM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS14850
gene id: 323261:NOC_RS14850
uniprot id: Q3J7E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

323261:NOC RS15925
gene id: 323261:NOC_RS15925
uniprot id: Q3J6U6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS14845
gene id: 323261:NOC_RS14845
uniprot id: Q3J7F0
names: Subcellular Location Annotation
messages: Cytoplasm

323261:NOC RS08480
gene id: 323261:NOC_RS08480
uniprot id: Q3JAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS15935
gene id: 323261:NOC_RS15935
uniprot id: Q3J6U4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

323261:NOC RS04795
gene id: 323261:NOC_RS04795
uniprot id: Q3JCQ2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS09525
gene id: 323261:NOC_RS09525
uniprot id: Q3JAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

323261:NOC RS08975
gene id: 323261:NOC_RS08975
uniprot id: Q3JAL2
names: Similarity
names: Subunit
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

323261:NOC RS09020
gene id: 323261:NOC_RS09020
uniprot id: Q3JAK3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS15090
gene id: 323261:NOC_RS15090
uniprot id: Q3J7A3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS03905
gene id: 323261:NOC_RS03905
uniprot id: Q3JD73
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

323261:NOC RS06080
gene id: 323261:NOC_RS06080
uniprot id: Q3JC25
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS00775
gene id: 323261:NOC_RS00775
uniprot id: Q3JEU8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12095
gene id: 323261:NOC_RS12095
uniprot id: Q3J8X8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

323261:NOC RS00050
gene id: 323261:NOC_RS00050
uniprot id: Q3JF76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS06075
gene id: 323261:NOC_RS06075
uniprot id: Q3JC26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323261:NOC RS02460
gene id: 323261:NOC_RS02460
uniprot id: Q3JDY2
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

323261:NOC RS13590
gene id: 323261:NOC_RS13590
uniprot id: Q3J839
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS08930
gene id: 323261:NOC_RS08930
uniprot id: Q3JAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

323261:NOC RS01095
gene id: 323261:NOC_RS01095
uniprot id: Q3JEN8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

323261:NOC RS05990
gene id: 323261:NOC_RS05990
uniprot id: Q3JC42
names: Similarity
messages: Belongs to the YoeB family.

323261:NOC RS16195
gene id: 323261:NOC_RS16195
uniprot id: Q3J6P5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323261:NOC RS10395
gene id: 323261:NOC_RS10395
uniprot id: Q3J9V1
names: Similarity
messages: Belongs to the peptidase M16 family.

323261:NOC RS10865
gene id: 323261:NOC_RS10865
uniprot id: Q3J9K9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

323261:NOC RS06765
gene id: 323261:NOC_RS06765
uniprot id: Q3JBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

323261:NOC RS06055
gene id: 323261:NOC_RS06055
uniprot id: Q3JC30
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS07720
gene id: 323261:NOC_RS07720
uniprot id: Q3JB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Belongs to the ribosome association toxin RatA family.
messages: Membrane

323261:NOC RS14990
gene id: 323261:NOC_RS14990
uniprot id: Q3J7C1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

323261:NOC RS08380
gene id: 323261:NOC_RS08380
uniprot id: Q3JAV5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS11040
gene id: 323261:NOC_RS11040
uniprot id: Q3J9H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

323261:NOC RS04415
gene id: 323261:NOC_RS04415
uniprot id: Q3JCX5
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

323261:NOC RS12385
gene id: 323261:NOC_RS12385
uniprot id: Q3J8R9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).

323261:NOC RS01800
gene id: 323261:NOC_RS01800
uniprot id: Q3JEA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS01440
gene id: 323261:NOC_RS01440
uniprot id: Q3JEH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

323261:NOC RS13670
gene id: 323261:NOC_RS13670
uniprot id: Q3J825
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

323261:NOC RS15350
gene id: 323261:NOC_RS15350
uniprot id: Q3J750
names: Similarity
messages: Belongs to the SCO1/2 family.

323261:NOC RS01930
gene id: 323261:NOC_RS01930
uniprot id: Q3JE78
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

323261:NOC RS01675
gene id: 323261:NOC_RS01675
uniprot id: Q3JEC7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

323261:NOC RS15430
gene id: 323261:NOC_RS15430
uniprot id: Q3J734
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

323261:NOC RS08240
gene id: 323261:NOC_RS08240
uniprot id: Q3JAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323261:NOC RS13090
gene id: 323261:NOC_RS13090
uniprot id: Q3J8D8
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

323261:NOC RS01115
gene id: 323261:NOC_RS01115
uniprot id: Q3JEN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

323261:NOC RS13440
gene id: 323261:NOC_RS13440
uniprot id: Q3J868
names: Subcellular Location Annotation
messages: Cytoplasm

323261:NOC RS14965
gene id: 323261:NOC_RS14965
uniprot id: Q3J7C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

323261:NOC RS04700
gene id: 323261:NOC_RS04700
uniprot id: Q3JCS0
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the precorrin methyltransferase family.
messages: In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
messages: Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.

323261:NOC RS06825
gene id: 323261:NOC_RS06825
uniprot id: Q3JBP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

323261:NOC RS08265
gene id: 323261:NOC_RS08265
uniprot id: Q3JAX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323261:NOC RS05180
gene id: 323261:NOC_RS05180
uniprot id: Q3JCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (CcmA) and two transmembrane proteins (CcmB).

323261:NOC RS04720
gene id: 323261:NOC_RS04720
uniprot id: Q3JCR6
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

323261:NOC RS12680
gene id: 323261:NOC_RS12680
uniprot id: Q3J8L5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323261:NOC RS07490
gene id: 323261:NOC_RS07490
uniprot id: Q3JBC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323261:NOC RS08520
gene id: 323261:NOC_RS08520
uniprot id: Q3JAT5
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

323261:NOC RS09850
gene id: 323261:NOC_RS09850
uniprot id: Q3JA50
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS10720
gene id: 323261:NOC_RS10720
uniprot id: Q3J9N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

323261:NOC RS09975
gene id: 323261:NOC_RS09975
uniprot id: Q3JA26
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

323261:NOC RS13390
gene id: 323261:NOC_RS13390
uniprot id: Q3J878
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

323261:NOC RS06885
gene id: 323261:NOC_RS06885
uniprot id: Q3JBN2
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

323261:NOC RS06395
gene id: 323261:NOC_RS06395
uniprot id: Q3JBX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323261:NOC RS10830
gene id: 323261:NOC_RS10830
uniprot id: Q3J9L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

323261:NOC RS07770
gene id: 323261:NOC_RS07770
uniprot id: Q3JB70
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

323261:NOC RS05580
gene id: 323261:NOC_RS05580
uniprot id: Q3JCB5
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

323261:NOC RS12305
gene id: 323261:NOC_RS12305
uniprot id: Q3J8T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

323261:NOC RS12880
gene id: 323261:NOC_RS12880
uniprot id: Q3J8H6
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

323261:NOC RS03930
gene id: 323261:NOC_RS03930
uniprot id: Q3JD68
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

323261:NOC RS14495
gene id: 323261:NOC_RS14495
uniprot id: Q3J7L2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323261:NOC RS12315
gene id: 323261:NOC_RS12315
uniprot id: Q3J8T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

323261:NOC RS14920
gene id: 323261:NOC_RS14920
uniprot id: Q3J7D5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

323261:NOC RS01710
gene id: 323261:NOC_RS01710
uniprot id: Q3JEC0
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

323261:NOC RS09445
gene id: 323261:NOC_RS09445
uniprot id: Q3JAC4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

323261:NOC RS15910
gene id: 323261:NOC_RS15910
uniprot id: Q3J6V0
names: Similarity
messages: Belongs to the GSP E family.

323261:NOC RS11575
gene id: 323261:NOC_RS11575
uniprot id: Q3J971
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323261:NOC RS04705
gene id: 323261:NOC_RS04705
uniprot id: Q3JCR9
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

323261:NOC RS15540
gene id: 323261:NOC_RS15540
uniprot id: Q3J716
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

323261:NOC RS04960
gene id: 323261:NOC_RS04960
uniprot id: Q3JCM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS03065
gene id: 323261:NOC_RS03065
uniprot id: Q3JDL9
names: Function
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
messages: Catalyzes the biosynthesis of agmatine from arginine.

323261:NOC RS06245
gene id: 323261:NOC_RS06245
uniprot id: Q3JBZ7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323261:NOC RS09400
gene id: 323261:NOC_RS09400
uniprot id: Q3JAD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopC family.
messages: Involved in copper resistance.
messages: Periplasm

323261:NOC RS09010
gene id: 323261:NOC_RS09010
uniprot id: Q3JAK5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

323261:NOC RS12265
gene id: 323261:NOC_RS12265
uniprot id: Q3J8U5
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

323261:NOC RS15880
gene id: 323261:NOC_RS15880
uniprot id: Q3J6V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

323261:NOC RS13830
gene id: 323261:NOC_RS13830
uniprot id: Q3J7Z4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

323261:NOC RS02835
gene id: 323261:NOC_RS02835
uniprot id: Q3JDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

323261:NOC RS11580
gene id: 323261:NOC_RS11580
uniprot id: Q3J970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

323261:NOC RS01485
gene id: 323261:NOC_RS01485
uniprot id: Q3JEG4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS16300
gene id: 323261:NOC_RS16300
uniprot id: Q3J6M3
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

323261:NOC RS14810
gene id: 323261:NOC_RS14810
uniprot id: Q3J7F7
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

323261:NOC RS00970
gene id: 323261:NOC_RS00970
uniprot id: Q3JER0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323261:NOC RS06095
gene id: 323261:NOC_RS06095
uniprot id: Q3JC22
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS08770
gene id: 323261:NOC_RS08770
uniprot id: Q3JAP6
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS04320
gene id: 323261:NOC_RS04320
uniprot id: Q3JCZ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

323261:NOC RS12390
gene id: 323261:NOC_RS12390
uniprot id: Q3J8R8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

323261:NOC RS05685
gene id: 323261:NOC_RS05685
uniprot id: Q3JC94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

323261:NOC RS13375
gene id: 323261:NOC_RS13375
uniprot id: Q3J881
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323261:NOC RS10390
gene id: 323261:NOC_RS10390
uniprot id: Q3J9V2
names: Similarity
messages: Belongs to the peptidase M16 family.

323261:NOC RS14130
gene id: 323261:NOC_RS14130
uniprot id: Q3J7T3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

323261:NOC RS01335
gene id: 323261:NOC_RS01335
uniprot id: Q3JEJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

323261:NOC RS03505
gene id: 323261:NOC_RS03505
uniprot id: Q3JDE2
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

323261:NOC RS00910
gene id: 323261:NOC_RS00910
uniprot id: Q3JES2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

323261:NOC RS10530
gene id: 323261:NOC_RS10530
uniprot id: Q3J9S4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

323261:NOC RS09075
gene id: 323261:NOC_RS09075
uniprot id: Q3JAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

323261:NOC RS09750
gene id: 323261:NOC_RS09750
uniprot id: Q3JA67
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS01600
gene id: 323261:NOC_RS01600
uniprot id: Q3JEE2
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

323261:NOC RS12740
gene id: 323261:NOC_RS12740
uniprot id: Q3J8K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

323261:NOC RS15265
gene id: 323261:NOC_RS15265
uniprot id: Q3J768
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

323261:NOC RS14925
gene id: 323261:NOC_RS14925
uniprot id: Q3J7D4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

323261:NOC RS13595
gene id: 323261:NOC_RS13595
uniprot id: Q3J838
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS07760
gene id: 323261:NOC_RS07760
uniprot id: Q3JB72
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

323261:NOC RS12465
gene id: 323261:NOC_RS12465
uniprot id: Q3J8Q3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

323261:NOC RS12165
gene id: 323261:NOC_RS12165
uniprot id: Q3J8W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PilY1 family.
messages: Fimbrium

323261:NOC RS14135
gene id: 323261:NOC_RS14135
uniprot id: Q3J7T2
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

323261:NOC RS16165
gene id: 323261:NOC_RS16165
uniprot id: Q3J6Q1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

323261:NOC RS03330
gene id: 323261:NOC_RS03330
uniprot id: Q3JDH2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

323261:NOC RS08565
gene id: 323261:NOC_RS08565
uniprot id: Q3JAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

323261:NOC RS15270
gene id: 323261:NOC_RS15270
uniprot id: Q3J767
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

323261:NOC RS16315
gene id: 323261:NOC_RS16315
uniprot id: Q3J6M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

323261:NOC RS13635
gene id: 323261:NOC_RS13635
uniprot id: Q3J830
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS06860
gene id: 323261:NOC_RS06860
uniprot id: Q3JBN7
names: Similarity
messages: Belongs to the universal stress protein A family.

323261:NOC RS14200
gene id: 323261:NOC_RS14200
uniprot id: Q3J7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323261:NOC RS13385
gene id: 323261:NOC_RS13385
uniprot id: Q3J879
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein bS18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS14905
gene id: 323261:NOC_RS14905
uniprot id: Q3J7D8
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

323261:NOC RS15210
gene id: 323261:NOC_RS15210
uniprot id: Q3J779
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13265
gene id: 323261:NOC_RS13265
uniprot id: Q3J8A3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

323261:NOC RS00610
gene id: 323261:NOC_RS00610
uniprot id: Q3JEY0
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

323261:NOC RS02665
gene id: 323261:NOC_RS02665
uniprot id: Q3JDU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323261:NOC RS11005
gene id: 323261:NOC_RS11005
uniprot id: Q3J9I2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

323261:NOC RS00795
gene id: 323261:NOC_RS00795
uniprot id: Q3JEU5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12610
gene id: 323261:NOC_RS12610
uniprot id: Q3J8M8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

323261:NOC RS12940
gene id: 323261:NOC_RS12940
uniprot id: Q3J8G5
names: Similarity
messages: Belongs to the ClpA/ClpB family.

323261:NOC RS13220
gene id: 323261:NOC_RS13220
uniprot id: Q3J8B2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS02400
gene id: 323261:NOC_RS02400
uniprot id: Q3JDZ5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14755
gene id: 323261:NOC_RS14755
uniprot id: Q3J7G8
names: Similarity
messages: Belongs to the BolA/IbaG family.

323261:NOC RS14250
gene id: 323261:NOC_RS14250
uniprot id: Q3J7R0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

323261:NOC RS14785
gene id: 323261:NOC_RS14785
uniprot id: Q3J7G2
names: Similarity
messages: Belongs to the MlaA family.

323261:NOC RS14045
gene id: 323261:NOC_RS14045
uniprot id: Q3J7V0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323261:NOC RS03245
gene id: 323261:NOC_RS03245
uniprot id: Q3JDI8
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

323261:NOC RS12805
gene id: 323261:NOC_RS12805
uniprot id: Q3J8J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS09460
gene id: 323261:NOC_RS09460
uniprot id: Q3JAC1
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323261:NOC RS04425
gene id: 323261:NOC_RS04425
uniprot id: Q3JCX3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.

323261:NOC RS00245
gene id: 323261:NOC_RS00245
uniprot id: Q3JF38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

323261:NOC RS13610
gene id: 323261:NOC_RS13610
uniprot id: Q3J835
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

323261:NOC RS13740
gene id: 323261:NOC_RS13740
uniprot id: Q3J811
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. RhlB subfamily.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

323261:NOC RS06630
gene id: 323261:NOC_RS06630
uniprot id: Q3JBT0
names: Similarity
messages: Belongs to the RutC family.

323261:NOC RS07370
gene id: 323261:NOC_RS07370
uniprot id: Q3JBE4
names: Similarity
messages: Belongs to the UPF0260 family.

323261:NOC RS00055
gene id: 323261:NOC_RS00055
uniprot id: Q3JF75
names: Similarity
messages: Belongs to the DNase I family.

323261:NOC RS02075
gene id: 323261:NOC_RS02075
uniprot id: Q3JE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TamA family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS12580
gene id: 323261:NOC_RS12580
uniprot id: Q3J8N4
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

323261:NOC RS10265
gene id: 323261:NOC_RS10265
uniprot id: Q3J9X5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

323261:NOC RS14480
gene id: 323261:NOC_RS14480
uniprot id: Q3J7L5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

323261:NOC RS07520
gene id: 323261:NOC_RS07520
uniprot id: Q3JBB6
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

323261:NOC RS15150
gene id: 323261:NOC_RS15150
uniprot id: Q3J791
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

323261:NOC RS16295
gene id: 323261:NOC_RS16295
uniprot id: Q3J6M4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS09015
gene id: 323261:NOC_RS09015
uniprot id: Q3JAK4
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

323261:NOC RS06500
gene id: 323261:NOC_RS06500
uniprot id: Q3JBV3
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

323261:NOC RS12090
gene id: 323261:NOC_RS12090
uniprot id: Q3J8X9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

323261:NOC RS09295
gene id: 323261:NOC_RS09295
uniprot id: Q3JAF1
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
messages: Periplasm
messages: The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition.

323261:NOC RS01315
gene id: 323261:NOC_RS01315
uniprot id: Q3JEJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

323261:NOC RS15105
gene id: 323261:NOC_RS15105
uniprot id: Q3J7A0
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

323261:NOC RS07420
gene id: 323261:NOC_RS07420
uniprot id: Q3JBD5
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS10800
gene id: 323261:NOC_RS10800
uniprot id: Q3J9M2
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

323261:NOC RS06365
gene id: 323261:NOC_RS06365
uniprot id: Q3JBX8
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

323261:NOC RS05760
gene id: 323261:NOC_RS05760
uniprot id: Q3JC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

323261:NOC RS16100
gene id: 323261:NOC_RS16100
uniprot id: Q3J6R3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS14805
gene id: 323261:NOC_RS14805
uniprot id: Q3J7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

323261:NOC RS00380
gene id: 323261:NOC_RS00380
uniprot id: Q3JF20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

323261:NOC RS07670
gene id: 323261:NOC_RS07670
uniprot id: Q3JB89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

323261:NOC RS11165
gene id: 323261:NOC_RS11165
uniprot id: Q3J9F0
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06150
gene id: 323261:NOC_RS06150
uniprot id: Q3JC12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS02420
gene id: 323261:NOC_RS02420
uniprot id: Q3JDZ0
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS08385
gene id: 323261:NOC_RS08385
uniprot id: Q3JAV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PhyH family. EctD subfamily.
messages: Homodimer.
messages: Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine.

323261:NOC RS11810
gene id: 323261:NOC_RS11810
uniprot id: Q3J924
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

323261:NOC RS13085
gene id: 323261:NOC_RS13085
uniprot id: Q3J8D9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

323261:NOC RS15260
gene id: 323261:NOC_RS15260
uniprot id: Q3J769
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

323261:NOC RS00930
gene id: 323261:NOC_RS00930
uniprot id: Q3JER8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

323261:NOC RS13580
gene id: 323261:NOC_RS13580
uniprot id: Q3J841
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS12425
gene id: 323261:NOC_RS12425
uniprot id: Q3J8R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

323261:NOC RS14395
gene id: 323261:NOC_RS14395
uniprot id: Q3J7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS07315
gene id: 323261:NOC_RS07315
uniprot id: Q3JBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm

323261:NOC RS08465
gene id: 323261:NOC_RS08465
uniprot id: Q3JAU5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

323261:NOC RS10810
gene id: 323261:NOC_RS10810
uniprot id: Q3J9M0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

323261:NOC RS13920
gene id: 323261:NOC_RS13920
uniprot id: Q3J7X6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

323261:NOC RS04590
gene id: 323261:NOC_RS04590
uniprot id: Q3JCU1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

323261:NOC RS03350
gene id: 323261:NOC_RS03350
uniprot id: Q3JDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

323261:NOC RS05510
gene id: 323261:NOC_RS05510
uniprot id: Q3JCC9
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

323261:NOC RS12700
gene id: 323261:NOC_RS12700
uniprot id: Q3J8L1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

323261:NOC RS03210
gene id: 323261:NOC_RS03210
uniprot id: Q3JDJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS13665
gene id: 323261:NOC_RS13665
uniprot id: Q3J826
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

323261:NOC RS08775
gene id: 323261:NOC_RS08775
uniprot id: Q3JAP5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

323261:NOC RS06635
gene id: 323261:NOC_RS06635
uniprot id: Q3JBS9
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

323261:NOC RS13620
gene id: 323261:NOC_RS13620
uniprot id: Q3J833
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

323261:NOC RS07115
gene id: 323261:NOC_RS07115
uniprot id: Q3JBJ0
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

323261:NOC RS01340
gene id: 323261:NOC_RS01340
uniprot id: Q3JEJ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

323261:NOC RS15730
gene id: 323261:NOC_RS15730
uniprot id: Q3J6Y5
names: Similarity
messages: Belongs to the SCO1/2 family.

323261:NOC RS05515
gene id: 323261:NOC_RS05515
uniprot id: Q3JCC8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS16635
gene id: 323261:NOC_RS16635
uniprot id: Q3JDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

323261:NOC RS13005
gene id: 323261:NOC_RS13005
uniprot id: Q3J8F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

323261:NOC RS12100
gene id: 323261:NOC_RS12100
uniprot id: Q3J8X7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

323261:NOC RS14795
gene id: 323261:NOC_RS14795
uniprot id: Q3J7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

323261:NOC RS08100
gene id: 323261:NOC_RS08100
uniprot id: Q3JB07
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06815
gene id: 323261:NOC_RS06815
uniprot id: Q3JBP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323261:NOC RS02070
gene id: 323261:NOC_RS02070
uniprot id: Q3JE51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

323261:NOC RS09395
gene id: 323261:NOC_RS09395
uniprot id: Q3JAD3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CopD family.
messages: Cell inner membrane
messages: Involved in copper resistance.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

323261:NOC RS09190
gene id: 323261:NOC_RS09190
uniprot id: Q3JAH2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

323261:NOC RS05605
gene id: 323261:NOC_RS05605
uniprot id: Q3JCB0
names: Function
names: Similarity
messages: Belongs to the ectoine synthase family.
messages: Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.

323261:NOC RS14980
gene id: 323261:NOC_RS14980
uniprot id: Q3J7C3
names: Similarity
messages: Belongs to the phosphoribulokinase family.

323261:NOC RS12440
gene id: 323261:NOC_RS12440
uniprot id: Q3J8Q8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323261:NOC RS12640
gene id: 323261:NOC_RS12640
uniprot id: Q3J8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

323261:NOC RS09435
gene id: 323261:NOC_RS09435
uniprot id: Q3JAC6
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14600
gene id: 323261:NOC_RS14600
uniprot id: Q3J7J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

323261:NOC RS08650
gene id: 323261:NOC_RS08650
uniprot id: Q3JAR7
names: Similarity
messages: Belongs to the glutamate synthase family.

323261:NOC RS12485
gene id: 323261:NOC_RS12485
uniprot id: Q3J8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

323261:NOC RS05935
gene id: 323261:NOC_RS05935
uniprot id: Q3JC50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

323261:NOC RS15200
gene id: 323261:NOC_RS15200
uniprot id: Q3J781
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

323261:NOC RS13625
gene id: 323261:NOC_RS13625
uniprot id: Q3J832
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

323261:NOC RS11145
gene id: 323261:NOC_RS11145
uniprot id: Q3J9F4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

323261:NOC RS12750
gene id: 323261:NOC_RS12750
uniprot id: Q3J8K1
names: Similarity
messages: Belongs to the BolA/IbaG family.

323261:NOC RS01105
gene id: 323261:NOC_RS01105
uniprot id: Q3JEN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS11130
gene id: 323261:NOC_RS11130
uniprot id: Q3J9F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

323261:NOC RS02985
gene id: 323261:NOC_RS02985
uniprot id: Q3JDN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS13040
gene id: 323261:NOC_RS13040
uniprot id: Q3J8E8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

323261:NOC RS15170
gene id: 323261:NOC_RS15170
uniprot id: Q3J787
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

323261:NOC RS16035
gene id: 323261:NOC_RS16035
uniprot id: Q3J6S5
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

323261:NOC RS05045
gene id: 323261:NOC_RS05045
uniprot id: Q3JCL1
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

323261:NOC RS14490
gene id: 323261:NOC_RS14490
uniprot id: Q3J7L3
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

323261:NOC RS11115
gene id: 323261:NOC_RS11115
uniprot id: Q3J9G0
names: Similarity
messages: Belongs to the peptidase M16 family.

323261:NOC RS06505
gene id: 323261:NOC_RS06505
uniprot id: Q3JBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS03955
gene id: 323261:NOC_RS03955
uniprot id: Q3JD63
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

323261:NOC RS15025
gene id: 323261:NOC_RS15025
uniprot id: Q3J7B5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane

323261:NOC RS02825
gene id: 323261:NOC_RS02825
uniprot id: Q3JDR3
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

323261:NOC RS14175
gene id: 323261:NOC_RS14175
uniprot id: Q3J7S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

323261:NOC RS16275
gene id: 323261:NOC_RS16275
uniprot id: Q3J6M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

323261:NOC RS09590
gene id: 323261:NOC_RS09590
uniprot id: Q3JA97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

323261:NOC RS15140
gene id: 323261:NOC_RS15140
uniprot id: Q3J793
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

323261:NOC RS02300
gene id: 323261:NOC_RS02300
uniprot id: Q3JE08
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

323261:NOC RS14960
gene id: 323261:NOC_RS14960
uniprot id: Q3J7C7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm

323261:NOC RS09300
gene id: 323261:NOC_RS09300
uniprot id: Q3JAF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

323261:NOC RS12215
gene id: 323261:NOC_RS12215
uniprot id: Q3J8V4
names: Similarity
messages: Belongs to the UPF0166 family.

323261:NOC RS04675
gene id: 323261:NOC_RS04675
uniprot id: Q3JCS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS05150
gene id: 323261:NOC_RS05150
uniprot id: Q3JCJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

323261:NOC RS06980
gene id: 323261:NOC_RS06980
uniprot id: Q3JBL4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS10335
gene id: 323261:NOC_RS10335
uniprot id: Q3J9W3
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14190
gene id: 323261:NOC_RS14190
uniprot id: Q3J7S1
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS02855
gene id: 323261:NOC_RS02855
uniprot id: Q3JDQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

323261:NOC RS00900
gene id: 323261:NOC_RS00900
uniprot id: Q3JES4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

323261:NOC RS03840
gene id: 323261:NOC_RS03840
uniprot id: Q3JD86
names: Similarity
messages: Belongs to the site-specific recombinase resolvase family.

323261:NOC RS11340
gene id: 323261:NOC_RS11340
uniprot id: Q3J9B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

323261:NOC RS00965
gene id: 323261:NOC_RS00965
uniprot id: Q3JER1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS06130
gene id: 323261:NOC_RS06130
uniprot id: Q3JC15
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS05160
gene id: 323261:NOC_RS05160
uniprot id: Q3JCJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

323261:NOC RS03910
gene id: 323261:NOC_RS03910
uniprot id: Q3JD72
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

323261:NOC RS01690
gene id: 323261:NOC_RS01690
uniprot id: Q3JEC4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS01685
gene id: 323261:NOC_RS01685
uniprot id: Q3JEC5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323261:NOC RS04350
gene id: 323261:NOC_RS04350
uniprot id: Q3JCY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

323261:NOC RS01355
gene id: 323261:NOC_RS01355
uniprot id: Q3JEJ1
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

323261:NOC RS00905
gene id: 323261:NOC_RS00905
uniprot id: Q3JES3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

323261:NOC RS12810
gene id: 323261:NOC_RS12810
uniprot id: Q3J8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323261:NOC RS15825
gene id: 323261:NOC_RS15825
uniprot id: Q3J6W6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

323261:NOC RS15960
gene id: 323261:NOC_RS15960
uniprot id: Q3J6T9
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

323261:NOC RS08895
gene id: 323261:NOC_RS08895
uniprot id: Q3JAM7
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

323261:NOC RS05130
gene id: 323261:NOC_RS05130
uniprot id: Q3JCJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

323261:NOC RS04175
gene id: 323261:NOC_RS04175
uniprot id: Q3JD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family. GSP D subfamily.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS09250
gene id: 323261:NOC_RS09250
uniprot id: Q3JAG0
names: Similarity
messages: Belongs to the YkuD family.

323261:NOC RS15070
gene id: 323261:NOC_RS15070
uniprot id: Q3J7A7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

323261:NOC RS06145
gene id: 323261:NOC_RS06145
uniprot id: Q3JC13
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS05655
gene id: 323261:NOC_RS05655
uniprot id: Q3JCA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS04920
gene id: 323261:NOC_RS04920
uniprot id: Q3JCN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

323261:NOC RS00345
gene id: 323261:NOC_RS00345
uniprot id: Q3JF27
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS16310
gene id: 323261:NOC_RS16310
uniprot id: Q3J6M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

323261:NOC RS07815
gene id: 323261:NOC_RS07815
uniprot id: Q3JB61
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

323261:NOC RS04520
gene id: 323261:NOC_RS04520
uniprot id: Q3JCV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
messages: Homodimer.
messages: Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.

323261:NOC RS04465
gene id: 323261:NOC_RS04465
uniprot id: Q3JCW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

323261:NOC RS12275
gene id: 323261:NOC_RS12275
uniprot id: Q3J8U3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS03265
gene id: 323261:NOC_RS03265
uniprot id: Q3JDI5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

323261:NOC RS14735
gene id: 323261:NOC_RS14735
uniprot id: Q3J7H2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

323261:NOC RS01180
gene id: 323261:NOC_RS01180
uniprot id: Q3JEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323261:NOC RS06550
gene id: 323261:NOC_RS06550
uniprot id: Q3JBU4
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS01815
gene id: 323261:NOC_RS01815
uniprot id: Q3JE99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS09410
gene id: 323261:NOC_RS09410
uniprot id: Q3JAD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

323261:NOC RS15385
gene id: 323261:NOC_RS15385
uniprot id: Q3J743
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

323261:NOC RS08320
gene id: 323261:NOC_RS08320
uniprot id: Q3JAW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

323261:NOC RS09230
gene id: 323261:NOC_RS09230
uniprot id: Q3JAG4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

323261:NOC RS09140
gene id: 323261:NOC_RS09140
uniprot id: Q3JAI3
names: Similarity
messages: Belongs to the UPF0047 family.

323261:NOC RS14870
gene id: 323261:NOC_RS14870
uniprot id: Q3J7E5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

323261:NOC RS13170
gene id: 323261:NOC_RS13170
uniprot id: Q3J8C2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS12085
gene id: 323261:NOC_RS12085
uniprot id: Q3J8Y0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

323261:NOC RS01455
gene id: 323261:NOC_RS01455
uniprot id: Q3JEH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

323261:NOC RS14645
gene id: 323261:NOC_RS14645
uniprot id: Q3J7I7
names: Function
messages: Mediates the mercuric-dependent induction of mercury resistance operon. In the absence of mercury MerR represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site.

323261:NOC RS06800
gene id: 323261:NOC_RS06800
uniprot id: Q3JBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

323261:NOC RS13780
gene id: 323261:NOC_RS13780
uniprot id: Q3J803
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

323261:NOC RS04505
gene id: 323261:NOC_RS04505
uniprot id: Q3JCV7
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

323261:NOC RS04940
gene id: 323261:NOC_RS04940
uniprot id: Q3JCM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

323261:NOC RS16125
gene id: 323261:NOC_RS16125
uniprot id: Q3J6Q8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

323261:NOC RS07320
gene id: 323261:NOC_RS07320
uniprot id: Q3JBF3
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

323261:NOC RS01810
gene id: 323261:NOC_RS01810
uniprot id: Q3JEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

323261:NOC RS08870
gene id: 323261:NOC_RS08870
uniprot id: Q3JAN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

323261:NOC RS05105
gene id: 323261:NOC_RS05105
uniprot id: Q3JCK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323261:NOC RS07275
gene id: 323261:NOC_RS07275
uniprot id: Q3JBG2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS09645
gene id: 323261:NOC_RS09645
uniprot id: Q3JA87
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

323261:NOC RS05195
gene id: 323261:NOC_RS05195
uniprot id: Q3JCI4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

323261:NOC RS06830
gene id: 323261:NOC_RS06830
uniprot id: Q3JBP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323261:NOC RS06495
gene id: 323261:NOC_RS06495
uniprot id: Q3JBV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

323261:NOC RS04385
gene id: 323261:NOC_RS04385
uniprot id: Q3JCY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

323261:NOC RS11865
gene id: 323261:NOC_RS11865
uniprot id: Q3J914
names: Similarity
messages: Belongs to the D-alanine--D-alanine ligase family.

323261:NOC RS04910
gene id: 323261:NOC_RS04910
uniprot id: Q3JCN2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS05705
gene id: 323261:NOC_RS05705
uniprot id: Q3JC90
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

323261:NOC RS12145
gene id: 323261:NOC_RS12145
uniprot id: Q3J8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP H family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS13815
gene id: 323261:NOC_RS13815
uniprot id: Q3J7Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

323261:NOC RS05570
gene id: 323261:NOC_RS05570
uniprot id: Q3JCB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

323261:NOC RS12180
gene id: 323261:NOC_RS12180
uniprot id: Q3J8W1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

323261:NOC RS14900
gene id: 323261:NOC_RS14900
uniprot id: Q3J7D9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

323261:NOC RS13925
gene id: 323261:NOC_RS13925
uniprot id: Q3J7X5
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

323261:NOC RS02815
gene id: 323261:NOC_RS02815
uniprot id: Q3JDR5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

323261:NOC RS13225
gene id: 323261:NOC_RS13225
uniprot id: Q3J8B1
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

323261:NOC RS02015
gene id: 323261:NOC_RS02015
uniprot id: Q3JE62
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS11930
gene id: 323261:NOC_RS11930
uniprot id: Q3J901
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

323261:NOC RS05155
gene id: 323261:NOC_RS05155
uniprot id: Q3JCJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS14970
gene id: 323261:NOC_RS14970
uniprot id: Q3J7C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

323261:NOC RS06515
gene id: 323261:NOC_RS06515
uniprot id: Q3JBV0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS08815
gene id: 323261:NOC_RS08815
uniprot id: Q3JAN9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

323261:NOC RS13100
gene id: 323261:NOC_RS13100
uniprot id: Q3J8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

323261:NOC RS13395
gene id: 323261:NOC_RS13395
uniprot id: Q3J877
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS12705
gene id: 323261:NOC_RS12705
uniprot id: Q3J8L0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

323261:NOC RS13585
gene id: 323261:NOC_RS13585
uniprot id: Q3J840
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

323261:NOC RS12965
gene id: 323261:NOC_RS12965
uniprot id: Q3J8G0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

323261:NOC RS09145
gene id: 323261:NOC_RS09145
uniprot id: Q3JAI1
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

323261:NOC RS05065
gene id: 323261:NOC_RS05065
uniprot id: Q3JCK7
names: Similarity
messages: Belongs to the aspartokinase family.

323261:NOC RS05385
gene id: 323261:NOC_RS05385
uniprot id: Q3JCF2
names: Caution
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS14105
gene id: 323261:NOC_RS14105
uniprot id: Q3J7T8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

323261:NOC RS10275
gene id: 323261:NOC_RS10275
uniprot id: Q3J9X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

323261:NOC RS09150
gene id: 323261:NOC_RS09150
uniprot id: Q3JAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

323261:NOC RS16320
gene id: 323261:NOC_RS16320
uniprot id: Q3J6L9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.

323261:NOC RS01910
gene id: 323261:NOC_RS01910
uniprot id: Q3JE82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

323261:NOC RS10935
gene id: 323261:NOC_RS10935
uniprot id: Q3J9J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

323261:NOC RS16090
gene id: 323261:NOC_RS16090
uniprot id: Q3J6R5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS01775
gene id: 323261:NOC_RS01775
uniprot id: Q3JEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS03960
gene id: 323261:NOC_RS03960
uniprot id: Q3JD62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS06795
gene id: 323261:NOC_RS06795
uniprot id: Q3JBQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

323261:NOC RS05520
gene id: 323261:NOC_RS05520
uniprot id: Q3JCC7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

323261:NOC RS06210
gene id: 323261:NOC_RS06210
uniprot id: Q3JC03
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

323261:NOC RS16210
gene id: 323261:NOC_RS16210
uniprot id: Q3J6P2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS01035
gene id: 323261:NOC_RS01035
uniprot id: Q3JEP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

323261:NOC RS04230
gene id: 323261:NOC_RS04230
uniprot id: Q3JD12
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

323261:NOC RS04885
gene id: 323261:NOC_RS04885
uniprot id: Q3JCN7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS04280
gene id: 323261:NOC_RS04280
uniprot id: Q3JD02
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

323261:NOC RS10930
gene id: 323261:NOC_RS10930
uniprot id: Q3J9J7
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

323261:NOC RS13455
gene id: 323261:NOC_RS13455
uniprot id: Q3J865
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

323261:NOC RS09790
gene id: 323261:NOC_RS09790
uniprot id: Q3JA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

323261:NOC RS16000
gene id: 323261:NOC_RS16000
uniprot id: Q3J6T1
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

323261:NOC RS07205
gene id: 323261:NOC_RS07205
uniprot id: Q3JBH4
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

323261:NOC RS08345
gene id: 323261:NOC_RS08345
uniprot id: Q3JAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

323261:NOC RS03230
gene id: 323261:NOC_RS03230
uniprot id: Q3JDJ1
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

323261:NOC RS07110
gene id: 323261:NOC_RS07110
uniprot id: Q3JBJ1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

323261:NOC RS13030
gene id: 323261:NOC_RS13030
uniprot id: Q3J8F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

323261:NOC RS02810
gene id: 323261:NOC_RS02810
uniprot id: Q3JDR6
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

323261:NOC RS06060
gene id: 323261:NOC_RS06060
uniprot id: Q3JC29
names: Subcellular Location Annotation
messages: Cell inner membrane

323261:NOC RS16330
gene id: 323261:NOC_RS16330
uniprot id: Q3J6L7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

323261:NOC RS04585
gene id: 323261:NOC_RS04585
uniprot id: Q3JCU2
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

323261:NOC RS01670
gene id: 323261:NOC_RS01670
uniprot id: Q3JEC8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

323261:NOC RS09155
gene id: 323261:NOC_RS09155
uniprot id: Q3JAH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

323261:NOC RS13080
gene id: 323261:NOC_RS13080
uniprot id: Q3J8E0
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

323261:NOC RS12110
gene id: 323261:NOC_RS12110
uniprot id: Q3J8X5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS15030
gene id: 323261:NOC_RS15030
uniprot id: Q3J7B4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

323261:NOC RS13115
gene id: 323261:NOC_RS13115
uniprot id: Q3J8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

323261:NOC RS03035
gene id: 323261:NOC_RS03035
uniprot id: Q3JDM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

323261:NOC RS01735
gene id: 323261:NOC_RS01735
uniprot id: Q3JEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS16070
gene id: 323261:NOC_RS16070
uniprot id: Q3J6R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

323261:NOC RS10400
gene id: 323261:NOC_RS10400
uniprot id: Q3J9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

323261:NOC RS04325
gene id: 323261:NOC_RS04325
uniprot id: Q3JCZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

323261:NOC RS04815
gene id: 323261:NOC_RS04815
uniprot id: Q3JCQ0
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

323261:NOC RS13300
gene id: 323261:NOC_RS13300
uniprot id: Q3J896
names: Similarity
messages: Belongs to the TrpC family.

323261:NOC RS09760
gene id: 323261:NOC_RS09760
uniprot id: Q3JA65
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

323261:NOC RS15595
gene id: 323261:NOC_RS15595
uniprot id: Q3J708
names: Similarity
messages: Belongs to the peptidase C59 family.

323261:NOC RS06445
gene id: 323261:NOC_RS06445
uniprot id: Q3JBW3
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

323261:NOC RS14430
gene id: 323261:NOC_RS14430
uniprot id: Q3J7M5
names: Similarity
messages: In the N-terminal section; belongs to the HAD-like hydrolase superfamily.

323261:NOC RS16325
gene id: 323261:NOC_RS16325
uniprot id: Q3J6L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

323261:NOC RS00360
gene id: 323261:NOC_RS00360
uniprot id: Q3JF24
names: Similarity
messages: Belongs to the peptidase S41A family.

323261:NOC RS09175
gene id: 323261:NOC_RS09175
uniprot id: Q3JAH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

323261:NOC RS10780
gene id: 323261:NOC_RS10780
uniprot id: Q3J9M5
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

323261:NOC RS12420
gene id: 323261:NOC_RS12420
uniprot id: Q3J8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

323261:NOC RS00405
gene id: 323261:NOC_RS00405
uniprot id: Q3JF15
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

323261:NOC RS02840
gene id: 323261:NOC_RS02840
uniprot id: Q3JDR0
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

323261:NOC RS10465
gene id: 323261:NOC_RS10465
uniprot id: Q3J9T7
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13600
gene id: 323261:NOC_RS13600
uniprot id: Q3J837
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS04635
gene id: 323261:NOC_RS04635
uniprot id: Q3JCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

323261:NOC RS08890
gene id: 323261:NOC_RS08890
uniprot id: Q3JAM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS09805
gene id: 323261:NOC_RS09805
uniprot id: Q3JA56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS04745
gene id: 323261:NOC_RS04745
uniprot id: Q3JCR1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

323261:NOC RS14270
gene id: 323261:NOC_RS14270
uniprot id: Q3J7Q7
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

323261:NOC RS00990
gene id: 323261:NOC_RS00990
uniprot id: Q3JEQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

323261:NOC RS03300
gene id: 323261:NOC_RS03300
uniprot id: Q3JDH8
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

323261:NOC RS11545
gene id: 323261:NOC_RS11545
uniprot id: Q3J977
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

323261:NOC RS09610
gene id: 323261:NOC_RS09610
uniprot id: Q3JA93
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

323261:NOC RS11505
gene id: 323261:NOC_RS11505
uniprot id: Q3J985
names: Similarity
messages: Belongs to the MscS (TC 1.A.23) family.

323261:NOC RS13205
gene id: 323261:NOC_RS13205
uniprot id: Q3J8B5
names: Similarity
messages: Belongs to the asparagine synthetase family.

323261:NOC RS04540
gene id: 323261:NOC_RS04540
uniprot id: Q3JCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

323261:NOC RS04735
gene id: 323261:NOC_RS04735
uniprot id: Q3JCR3
names: Similarity
messages: Belongs to the HSP15 family.

323261:NOC RS05565
gene id: 323261:NOC_RS05565
uniprot id: Q3JCB8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

323261:NOC RS06450
gene id: 323261:NOC_RS06450
uniprot id: Q3JBW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

323261:NOC RS13160
gene id: 323261:NOC_RS13160
uniprot id: Q3J8C4
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

323261:NOC RS13775
gene id: 323261:NOC_RS13775
uniprot id: Q3J804
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

323261:NOC RS02650
gene id: 323261:NOC_RS02650
uniprot id: Q3JDU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS03935
gene id: 323261:NOC_RS03935
uniprot id: Q3JD67
names: Similarity
messages: Belongs to the P(II) protein family.

323261:NOC RS11660
gene id: 323261:NOC_RS11660
uniprot id: Q3J953
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

323261:NOC RS12130
gene id: 323261:NOC_RS12130
uniprot id: Q3J8X1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

323261:NOC RS10740
gene id: 323261:NOC_RS10740
uniprot id: Q3J9N2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

323261:NOC RS13850
gene id: 323261:NOC_RS13850
uniprot id: Q3J7Z0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

323261:NOC RS09375
gene id: 323261:NOC_RS09375
uniprot id: Q3JAD7
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

323261:NOC RS15180
gene id: 323261:NOC_RS15180
uniprot id: Q3J785
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

323261:NOC RS01085
gene id: 323261:NOC_RS01085
uniprot id: Q3JEP0
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

323261:NOC RS04155
gene id: 323261:NOC_RS04155
uniprot id: Q3JD26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS10280
gene id: 323261:NOC_RS10280
uniprot id: Q3J9X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

323261:NOC RS07650
gene id: 323261:NOC_RS07650
uniprot id: Q3JB93
names: Function
names: Similarity
messages: Belongs to the HARP family.
messages: RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.

323261:NOC RS07565
gene id: 323261:NOC_RS07565
uniprot id: Q3JBA7
names: Similarity
messages: Belongs to the peptidase S1C family.

323261:NOC RS15800
gene id: 323261:NOC_RS15800
uniprot id: Q3J6X1
names: Similarity
messages: Belongs to the group II decarboxylase family.

323261:NOC RS08990
gene id: 323261:NOC_RS08990
uniprot id: Q3JAK9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

323261:NOC RS06965
gene id: 323261:NOC_RS06965
uniprot id: Q3JBL7
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS04410
gene id: 323261:NOC_RS04410
uniprot id: Q3JCX6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

323261:NOC RS12195
gene id: 323261:NOC_RS12195
uniprot id: Q3J8V8
names: Similarity
messages: Belongs to the UDPGP type 2 family.

323261:NOC RS01950
gene id: 323261:NOC_RS01950
uniprot id: Q3JE75
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

323261:NOC RS05575
gene id: 323261:NOC_RS05575
uniprot id: Q3JCB6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

323261:NOC RS01635
gene id: 323261:NOC_RS01635
uniprot id: Q3JED5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323261:NOC RS05070
gene id: 323261:NOC_RS05070
uniprot id: Q3JCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

323261:NOC RS12205
gene id: 323261:NOC_RS12205
uniprot id: Q3J8V6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

323261:NOC RS01140
gene id: 323261:NOC_RS01140
uniprot id: Q3JEM9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

323261:NOC RS03195
gene id: 323261:NOC_RS03195
uniprot id: Q3JDJ8
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

323261:NOC RS13790
gene id: 323261:NOC_RS13790
uniprot id: Q3J801
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS16280
gene id: 323261:NOC_RS16280
uniprot id: Q3J6M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

323261:NOC RS15955
gene id: 323261:NOC_RS15955
uniprot id: Q3J6U0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

323261:NOC RS03040
gene id: 323261:NOC_RS03040
uniprot id: Q3JDM4
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

323261:NOC RS12790
gene id: 323261:NOC_RS12790
uniprot id: Q3J8J4
names: Similarity
messages: Belongs to the GppA/Ppx family.

323261:NOC RS06410
gene id: 323261:NOC_RS06410
uniprot id: Q3JBW9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323261:NOC RS12380
gene id: 323261:NOC_RS12380
uniprot id: Q3J8S0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

323261:NOC RS11325
gene id: 323261:NOC_RS11325
uniprot id: Q3J9B9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

323261:NOC RS14240
gene id: 323261:NOC_RS14240
uniprot id: Q3J7R2
names: Cofactor
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.

323261:NOC RS14015
gene id: 323261:NOC_RS14015
uniprot id: Q3J7V6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

323261:NOC RS06605
gene id: 323261:NOC_RS06605
uniprot id: Q3JBT5
names: Similarity
messages: Belongs to the PhoH family.

323261:NOC RS06435
gene id: 323261:NOC_RS06435
uniprot id: Q3JBW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS00895
gene id: 323261:NOC_RS00895
uniprot id: Q3JES5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

323261:NOC RS11170
gene id: 323261:NOC_RS11170
uniprot id: Q3J9E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Membrane

323261:NOC RS12935
gene id: 323261:NOC_RS12935
uniprot id: Q3J8G6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS06820
gene id: 323261:NOC_RS06820
uniprot id: Q3JBP5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS08045
gene id: 323261:NOC_RS08045
uniprot id: Q3JB18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.
messages: Membrane

323261:NOC RS09910
gene id: 323261:NOC_RS09910
uniprot id: Q3JA38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

323261:NOC RS13905
gene id: 323261:NOC_RS13905
uniprot id: Q3J7X9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

323261:NOC RS07830
gene id: 323261:NOC_RS07830
uniprot id: Q3JB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323261:NOC RS11665
gene id: 323261:NOC_RS11665
uniprot id: Q3J952
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

323261:NOC RS06105
gene id: 323261:NOC_RS06105
uniprot id: Q3JC20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS16170
gene id: 323261:NOC_RS16170
uniprot id: Q3J6Q0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS01765
gene id: 323261:NOC_RS01765
uniprot id: Q3JEA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

323261:NOC RS00870
gene id: 323261:NOC_RS00870
uniprot id: Q3JET0
names: Similarity
messages: Belongs to the GPN-loop GTPase family.

323261:NOC RS07950
gene id: 323261:NOC_RS07950
uniprot id: Q3JB36
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

323261:NOC RS04310
gene id: 323261:NOC_RS04310
uniprot id: Q3JCZ6
names: Similarity
messages: Belongs to the peptidase S8 family.

323261:NOC RS03325
gene id: 323261:NOC_RS03325
uniprot id: Q3JDH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

323261:NOC RS07775
gene id: 323261:NOC_RS07775
uniprot id: Q3JB69
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

323261:NOC RS09160
gene id: 323261:NOC_RS09160
uniprot id: Q3JAH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

323261:NOC RS09795
gene id: 323261:NOC_RS09795
uniprot id: Q3JA58
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06110
gene id: 323261:NOC_RS06110
uniprot id: Q3JC19
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

323261:NOC RS01490
gene id: 323261:NOC_RS01490
uniprot id: Q3JEG3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

323261:NOC RS05840
gene id: 323261:NOC_RS05840
uniprot id: Q3JC68
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS02635
gene id: 323261:NOC_RS02635
uniprot id: Q3JDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

323261:NOC RS08995
gene id: 323261:NOC_RS08995
uniprot id: Q3JAK8
names: Similarity
messages: Belongs to the fabD family.

323261:NOC RS06140
gene id: 323261:NOC_RS06140
uniprot id: Q3JC14
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

323261:NOC RS12375
gene id: 323261:NOC_RS12375
uniprot id: Q3J8S1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

323261:NOC RS16190
gene id: 323261:NOC_RS16190
uniprot id: Q3J6P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

323261:NOC RS11345
gene id: 323261:NOC_RS11345
uniprot id: Q3J9B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

323261:NOC RS03215
gene id: 323261:NOC_RS03215
uniprot id: Q3JDJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

323261:NOC RS15455
gene id: 323261:NOC_RS15455
uniprot id: Q3J729
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

323261:NOC RS02105
gene id: 323261:NOC_RS02105
uniprot id: Q3JE44
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS00940
gene id: 323261:NOC_RS00940
uniprot id: Q3JER6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

323261:NOC RS12045
gene id: 323261:NOC_RS12045
uniprot id: Q3J8Y7
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

323261:NOC RS10235
gene id: 323261:NOC_RS10235
uniprot id: Q3J9Y1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

323261:NOC RS05740
gene id: 323261:NOC_RS05740
uniprot id: Q3JC83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbD subfamily.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.

323261:NOC RS01350
gene id: 323261:NOC_RS01350
uniprot id: Q3JEJ2
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

323261:NOC RS06405
gene id: 323261:NOC_RS06405
uniprot id: Q3JBX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323261:NOC RS05440
gene id: 323261:NOC_RS05440
uniprot id: Q3JCE2
names: Function
names: Similarity
messages: Belongs to the RecD family. RecD-like subfamily.
messages: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.

323261:NOC RS08230
gene id: 323261:NOC_RS08230
uniprot id: Q3JAY3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323261:NOC RS16265
gene id: 323261:NOC_RS16265
uniprot id: Q3J6N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

323261:NOC RS11870
gene id: 323261:NOC_RS11870
uniprot id: Q3J913
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS10650
gene id: 323261:NOC_RS10650
uniprot id: Q3J9Q0
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06735
gene id: 323261:NOC_RS06735
uniprot id: Q3JBR1
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

323261:NOC RS10805
gene id: 323261:NOC_RS10805
uniprot id: Q3J9M1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

323261:NOC RS14090
gene id: 323261:NOC_RS14090
uniprot id: Q3J7U1
names: Similarity
messages: Belongs to the glutamine synthetase family.

323261:NOC RS12035
gene id: 323261:NOC_RS12035
uniprot id: Q3J8Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Monomer.

323261:NOC RS12660
gene id: 323261:NOC_RS12660
uniprot id: Q3J8L9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

323261:NOC RS10085
gene id: 323261:NOC_RS10085
uniprot id: Q3JA06
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

323261:NOC RS02060
gene id: 323261:NOC_RS02060
uniprot id: Q3JE53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF nuclease family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

323261:NOC RS15790
gene id: 323261:NOC_RS15790
uniprot id: Q3J6X3
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

323261:NOC RS11140
gene id: 323261:NOC_RS11140
uniprot id: Q3J9F5
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

323261:NOC RS14365
gene id: 323261:NOC_RS14365
uniprot id: Q3J7N7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

323261:NOC RS03920
gene id: 323261:NOC_RS03920
uniprot id: Q3JD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

323261:NOC RS06280
gene id: 323261:NOC_RS06280
uniprot id: Q3JBZ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family. MetZ subfamily.
messages: Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.
messages: Homotetramer.

323261:NOC RS08335
gene id: 323261:NOC_RS08335
uniprot id: Q3JAW3
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

323261:NOC RS14210
gene id: 323261:NOC_RS14210
uniprot id: Q3J7R7
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

323261:NOC RS12535
gene id: 323261:NOC_RS12535
uniprot id: Q3J8P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell inner membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS04895
gene id: 323261:NOC_RS04895
uniprot id: Q3JCN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

323261:NOC RS04655
gene id: 323261:NOC_RS04655
uniprot id: Q3JCS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).

323261:NOC RS14835
gene id: 323261:NOC_RS14835
uniprot id: Q3J7F2
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

323261:NOC RS10745
gene id: 323261:NOC_RS10745
uniprot id: Q3J9N1
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

323261:NOC RS12555
gene id: 323261:NOC_RS12555
uniprot id: Q3J8N9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

323261:NOC RS00420
gene id: 323261:NOC_RS00420
uniprot id: Q3JF12
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

323261:NOC RS03745
gene id: 323261:NOC_RS03745
uniprot id: Q3JD98
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

323261:NOC RS12345
gene id: 323261:NOC_RS12345
uniprot id: Q3J8S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

323261:NOC RS15165
gene id: 323261:NOC_RS15165
uniprot id: Q3J788
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

323261:NOC RS09025
gene id: 323261:NOC_RS09025
uniprot id: Q3JAK2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13935
gene id: 323261:NOC_RS13935
uniprot id: Q3J7X3
names: Function
names: Similarity
messages: Belongs to the PqqB family.
messages: May be involved in the transport of PQQ or its precursor to the periplasm.

323261:NOC RS13420
gene id: 323261:NOC_RS13420
uniprot id: Q3J872
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

323261:NOC RS14815
gene id: 323261:NOC_RS14815
uniprot id: Q3J7F6
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

323261:NOC RS08730
gene id: 323261:NOC_RS08730
uniprot id: Q3JAQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS11295
gene id: 323261:NOC_RS11295
uniprot id: Q3J9C5
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

323261:NOC RS01920
gene id: 323261:NOC_RS01920
uniprot id: Q3JE80
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

323261:NOC RS08395
gene id: 323261:NOC_RS08395
uniprot id: Q3JAV2
names: Function
names: Similarity
messages: Belongs to the acetyltransferase family. EctA subfamily.
messages: Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.

323261:NOC RS13945
gene id: 323261:NOC_RS13945
uniprot id: Q3J7X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PqqD family.
messages: Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
messages: Monomer. Interacts with PqqE.

323261:NOC RS13910
gene id: 323261:NOC_RS13910
uniprot id: Q3J7X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

323261:NOC RS06100
gene id: 323261:NOC_RS06100
uniprot id: Q3JC21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

323261:NOC RS07635
gene id: 323261:NOC_RS07635
uniprot id: Q3JB96
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

323261:NOC RS06990
gene id: 323261:NOC_RS06990
uniprot id: Q3JBL2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

323261:NOC RS13355
gene id: 323261:NOC_RS13355
uniprot id: Q3J885
names: Similarity
messages: Belongs to the UPF0229 family.

323261:NOC RS07655
gene id: 323261:NOC_RS07655
uniprot id: Q3JB92
names: Similarity
messages: Belongs to the Nudix hydrolase family.

323261:NOC RS05860
gene id: 323261:NOC_RS05860
uniprot id: Q3JC64
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

323261:NOC RS13800
gene id: 323261:NOC_RS13800
uniprot id: Q3J800
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

323261:NOC RS12950
gene id: 323261:NOC_RS12950
uniprot id: Q3J8G3
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

323261:NOC RS12200
gene id: 323261:NOC_RS12200
uniprot id: Q3J8V7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

323261:NOC RS13105
gene id: 323261:NOC_RS13105
uniprot id: Q3J8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

323261:NOC RS08660
gene id: 323261:NOC_RS08660
uniprot id: Q3JAR5
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.

323261:NOC RS12525
gene id: 323261:NOC_RS12525
uniprot id: Q3J8P5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

323261:NOC RS11105
gene id: 323261:NOC_RS11105
uniprot id: Q3J9G2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

323261:NOC RS14225
gene id: 323261:NOC_RS14225
uniprot id: Q3J7R5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

323261:NOC RS12530
gene id: 323261:NOC_RS12530
uniprot id: Q3J8P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

323261:NOC RS04785
gene id: 323261:NOC_RS04785
uniprot id: Q3JCQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

323261:NOC RS13950
gene id: 323261:NOC_RS13950
uniprot id: Q3J7X0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. PqqE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
messages: Interacts with PqqD. The interaction is necessary for activity of PqqE.

323261:NOC RS08950
gene id: 323261:NOC_RS08950
uniprot id: Q3JAL7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

323261:NOC RS14910
gene id: 323261:NOC_RS14910
uniprot id: Q3J7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

323261:NOC RS11350
gene id: 323261:NOC_RS11350
uniprot id: Q3J9B4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

323261:NOC RS01285
gene id: 323261:NOC_RS01285
uniprot id: Q3JEK5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

323261:NOC RS15665
gene id: 323261:NOC_RS15665
uniprot id: Q3J6Z6
names: Similarity
messages: Belongs to the glutamate synthase family.

323261:NOC RS15125
gene id: 323261:NOC_RS15125
uniprot id: Q3J796
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

323261:NOC RS06285
gene id: 323261:NOC_RS06285
uniprot id: Q3JBZ0
names: Similarity
messages: Belongs to the UPF0047 family.

323261:NOC RS15835
gene id: 323261:NOC_RS15835
uniprot id: Q3J6W5
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

323261:NOC RS13690
gene id: 323261:NOC_RS13690
uniprot id: Q3J821
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS11795
gene id: 323261:NOC_RS11795
uniprot id: Q3J927
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.
messages: Homotetramer; dimer of dimers.
messages: Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.

323261:NOC RS13335
gene id: 323261:NOC_RS13335
uniprot id: Q3J889
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

323261:NOC RS04470
gene id: 323261:NOC_RS04470
uniprot id: Q3JCW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

323261:NOC RS14890
gene id: 323261:NOC_RS14890
uniprot id: Q3J7E1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

323261:NOC RS06655
gene id: 323261:NOC_RS06655
uniprot id: Q3JBS6
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

323261:NOC RS15320
gene id: 323261:NOC_RS15320
uniprot id: Q3J756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

323261:NOC RS14275
gene id: 323261:NOC_RS14275
uniprot id: Q3J7Q6
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS01590
gene id: 323261:NOC_RS01590
uniprot id: Q3JEE4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

323261:NOC RS12430
gene id: 323261:NOC_RS12430
uniprot id: Q3J8R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

323261:NOC RS00350
gene id: 323261:NOC_RS00350
uniprot id: Q3JF26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

323261:NOC RS11510
gene id: 323261:NOC_RS11510
uniprot id: Q3J984
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

323261:NOC RS07915
gene id: 323261:NOC_RS07915
uniprot id: Q3JB41
names: Similarity
messages: Belongs to the pirin family.

323261:NOC RS02865
gene id: 323261:NOC_RS02865
uniprot id: Q3JDQ6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

323261:NOC RS09870
gene id: 323261:NOC_RS09870
uniprot id: Q3JA46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

323261:NOC RS04495
gene id: 323261:NOC_RS04495
uniprot id: Q3JCV9
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

323261:NOC RS04245
gene id: 323261:NOC_RS04245
uniprot id: Q3JD09
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

323261:NOC RS16230
gene id: 323261:NOC_RS16230
uniprot id: Q3J6N7
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

323261:NOC RS00670
gene id: 323261:NOC_RS00670
uniprot id: Q3JEW9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

323261:NOC RS14205
gene id: 323261:NOC_RS14205
uniprot id: Q3J7R8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
messages: Cell inner membrane
messages: Homodimer.
messages: In MsbA the ATP-binding domain (NBD) and the transmembrane domain (TMD) are fused.
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.

323261:NOC RS12600
gene id: 323261:NOC_RS12600
uniprot id: Q3J8N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

323261:NOC RS04570
gene id: 323261:NOC_RS04570
uniprot id: Q3JCU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

323261:NOC RS02095
gene id: 323261:NOC_RS02095
uniprot id: Q3JE46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

323261:NOC RS02550
gene id: 323261:NOC_RS02550
uniprot id: Q3JDW6
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it has been shown that conserved amino acid substitutions in the substrate binding pocket convert the substrate specificity of this enzyme from 6-aminopurines to 6-oxopurines.
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS08865
gene id: 323261:NOC_RS08865
uniprot id: Q3JAN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

323261:NOC RS05640
gene id: 323261:NOC_RS05640
uniprot id: Q3JCA3
names: Similarity
messages: Belongs to the UPF0166 family.

323261:NOC RS05125
gene id: 323261:NOC_RS05125
uniprot id: Q3JCJ7
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

323261:NOC RS02010
gene id: 323261:NOC_RS02010
uniprot id: Q3JE63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

323261:NOC RS05590
gene id: 323261:NOC_RS05590
uniprot id: Q3JCB3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS05025
gene id: 323261:NOC_RS05025
uniprot id: Q3JCL5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

323261:NOC RS07160
gene id: 323261:NOC_RS07160
uniprot id: Q3JBI3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

323261:NOC RS06115
gene id: 323261:NOC_RS06115
uniprot id: Q3JC18
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

323261:NOC RS16075
gene id: 323261:NOC_RS16075
uniprot id: Q3J6R8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

323261:NOC RS13965
gene id: 323261:NOC_RS13965
uniprot id: Q3J7W6
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

323261:NOC RS11255
gene id: 323261:NOC_RS11255
uniprot id: Q3J9D3
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

323261:NOC RS05645
gene id: 323261:NOC_RS05645
uniprot id: Q3JCA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

323261:NOC RS12505
gene id: 323261:NOC_RS12505
uniprot id: Q3J8P9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

323261:NOC RS10515
gene id: 323261:NOC_RS10515
uniprot id: Q3J9S7
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

323261:NOC RS12745
gene id: 323261:NOC_RS12745
uniprot id: Q3J8K2
names: Similarity
messages: Belongs to the YciI family.

323261:NOC RS12030
gene id: 323261:NOC_RS12030
uniprot id: Q3J8Y9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

323261:NOC RS11010
gene id: 323261:NOC_RS11010
uniprot id: Q3J9I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323261:NOC RS03045
gene id: 323261:NOC_RS03045
uniprot id: Q3JDM3
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

323261:NOC RS11420
gene id: 323261:NOC_RS11420
uniprot id: Q3J9A2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS11285
gene id: 323261:NOC_RS11285
uniprot id: Q3J9C7
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

323261:NOC RS02515
gene id: 323261:NOC_RS02515
uniprot id: Q3JDX1
names: Similarity
messages: Belongs to the Gfa family.

323261:NOC RS01295
gene id: 323261:NOC_RS01295
uniprot id: Q3JEK3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

323261:NOC RS06975
gene id: 323261:NOC_RS06975
uniprot id: Q3JBL5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS06540
gene id: 323261:NOC_RS06540
uniprot id: Q3JBU5
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

323261:NOC RS05800
gene id: 323261:NOC_RS05800
uniprot id: Q3JC72
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12210
gene id: 323261:NOC_RS12210
uniprot id: Q3J8V5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

323261:NOC RS08985
gene id: 323261:NOC_RS08985
uniprot id: Q3JAL0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

323261:NOC RS14315
gene id: 323261:NOC_RS14315
uniprot id: Q3J7P6
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

323261:NOC RS05295
gene id: 323261:NOC_RS05295
uniprot id: Q3JCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

323261:NOC RS01345
gene id: 323261:NOC_RS01345
uniprot id: Q3JEJ3
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

323261:NOC RS01770
gene id: 323261:NOC_RS01770
uniprot id: Q3JEA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

323261:NOC RS01405
gene id: 323261:NOC_RS01405
uniprot id: Q3JEI1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

323261:NOC RS15085
gene id: 323261:NOC_RS15085
uniprot id: Q3J7A4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

323261:NOC RS04750
gene id: 323261:NOC_RS04750
uniprot id: Q3JCR0
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS03735
gene id: 323261:NOC_RS03735
uniprot id: Q3JDA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpxP/Spy family.
messages: Periplasm

323261:NOC RS13050
gene id: 323261:NOC_RS13050
uniprot id: Q3J8E6
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS02250
gene id: 323261:NOC_RS02250
uniprot id: Q3JE17
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

323261:NOC RS13770
gene id: 323261:NOC_RS13770
uniprot id: Q3J805
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

323261:NOC RS08820
gene id: 323261:NOC_RS08820
uniprot id: Q3JAN8
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS13840
gene id: 323261:NOC_RS13840
uniprot id: Q3J7Z2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

323261:NOC RS02800
gene id: 323261:NOC_RS02800
uniprot id: Q3JDR8
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

323261:NOC RS10825
gene id: 323261:NOC_RS10825
uniprot id: Q3J9L7
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

323261:NOC RS05265
gene id: 323261:NOC_RS05265
uniprot id: Q3JCH1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

323261:NOC RS02790
gene id: 323261:NOC_RS02790
uniprot id: Q3JDS0
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

323261:NOC RS09465
gene id: 323261:NOC_RS09465
uniprot id: Q3JAC0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

323261:NOC RS06250
gene id: 323261:NOC_RS06250
uniprot id: Q3JBZ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

323261:NOC RS14705
gene id: 323261:NOC_RS14705
uniprot id: Q3J7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

323261:NOC RS13165
gene id: 323261:NOC_RS13165
uniprot id: Q3J8C3
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

323261:NOC RS02860
gene id: 323261:NOC_RS02860
uniprot id: Q3JDQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

323261:NOC RS04435
gene id: 323261:NOC_RS04435
uniprot id: Q3JCX1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

323261:NOC RS09430
gene id: 323261:NOC_RS09430
uniprot id: Q3JAC7
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS00835
gene id: 323261:NOC_RS00835
uniprot id: Q3JET7
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

323261:NOC RS12365
gene id: 323261:NOC_RS12365
uniprot id: Q3J8S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

323261:NOC RS11320
gene id: 323261:NOC_RS11320
uniprot id: Q3J9C0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

323261:NOC RS02720
gene id: 323261:NOC_RS02720
uniprot id: Q3JDT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

323261:NOC RS12320
gene id: 323261:NOC_RS12320
uniprot id: Q3J8T2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

323261:NOC RS12720
gene id: 323261:NOC_RS12720
uniprot id: Q3J8K7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

323261:NOC RS12755
gene id: 323261:NOC_RS12755
uniprot id: Q3J8K0
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

323261:NOC RS14725
gene id: 323261:NOC_RS14725
uniprot id: Q3J7H4
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12770
gene id: 323261:NOC_RS12770
uniprot id: Q3J8J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic sulfate-binding protein family.
messages: Periplasm

323261:NOC RS03945
gene id: 323261:NOC_RS03945
uniprot id: Q3JD65
names: Similarity
messages: Belongs to the YkuD family.

323261:NOC RS05670
gene id: 323261:NOC_RS05670
uniprot id: Q3JC97
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

323261:NOC RS12515
gene id: 323261:NOC_RS12515
uniprot id: Q3J8P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

323261:NOC RS15940
gene id: 323261:NOC_RS15940
uniprot id: Q3J6U3
names: Similarity
messages: Belongs to the Smg family.

323261:NOC RS04780
gene id: 323261:NOC_RS04780
uniprot id: Q3JCQ5
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

323261:NOC RS00305
gene id: 323261:NOC_RS00305
uniprot id: Q3JF35
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

323261:NOC RS13630
gene id: 323261:NOC_RS13630
uniprot id: Q3J831
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS13135
gene id: 323261:NOC_RS13135
uniprot id: Q3J8C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

323261:NOC RS05730
gene id: 323261:NOC_RS05730
uniprot id: Q3JC85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

323261:NOC RS16255
gene id: 323261:NOC_RS16255
uniprot id: Q3J6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

323261:NOC RS07675
gene id: 323261:NOC_RS07675
uniprot id: Q3JB88
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS10910
gene id: 323261:NOC_RS10910
uniprot id: Q3J9K1
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

323261:NOC RS11330
gene id: 323261:NOC_RS11330
uniprot id: Q3J9B8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

323261:NOC RS00320
gene id: 323261:NOC_RS00320
uniprot id: Q3JF32
names: Similarity
messages: Belongs to the FwdC/FmdC family.

323261:NOC RS12260
gene id: 323261:NOC_RS12260
uniprot id: Q3J8U6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

323261:NOC RS07390
gene id: 323261:NOC_RS07390
uniprot id: Q3JBE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

323261:NOC RS09360
gene id: 323261:NOC_RS09360
uniprot id: Q3JAE0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

323261:NOC RS08275
gene id: 323261:NOC_RS08275
uniprot id: Q3JAX5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323261:NOC RS01400
gene id: 323261:NOC_RS01400
uniprot id: Q3JEI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS15505
gene id: 323261:NOC_RS15505
uniprot id: Q3J723
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

323261:NOC RS13915
gene id: 323261:NOC_RS13915
uniprot id: Q3J7X7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

323261:NOC RS12350
gene id: 323261:NOC_RS12350
uniprot id: Q3J8S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

323261:NOC RS14345
gene id: 323261:NOC_RS14345
uniprot id: Q3J7P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

323261:NOC RS12445
gene id: 323261:NOC_RS12445
uniprot id: Q3J8Q7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

323261:NOC RS05745
gene id: 323261:NOC_RS05745
uniprot id: Q3JC82
names: Similarity
messages: Belongs to the CutA family.

323261:NOC RS12685
gene id: 323261:NOC_RS12685
uniprot id: Q3J8L4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

323261:NOC RS02090
gene id: 323261:NOC_RS02090
uniprot id: Q3JE47
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

323261:NOC RS01540
gene id: 323261:NOC_RS01540
uniprot id: Q3JEF3
names: Cofactor
messages: Binds 1 copper ion per subunit.

323261:NOC RS14425
gene id: 323261:NOC_RS14425
uniprot id: Q3J7M6
names: Similarity
messages: Belongs to the XFP family.

323261:NOC RS10755
gene id: 323261:NOC_RS10755
uniprot id: Q3J9N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

323261:NOC RS13540
gene id: 323261:NOC_RS13540
uniprot id: Q3J849
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

323261:NOC RS12280
gene id: 323261:NOC_RS12280
uniprot id: Q3J8U2
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

323261:NOC RS09050
gene id: 323261:NOC_RS09050
uniprot id: Q3JAJ7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

323261:NOC RS07385
gene id: 323261:NOC_RS07385
uniprot id: Q3JBE1
names: Similarity
messages: Belongs to the GSP E family.

323261:NOC RS02080
gene id: 323261:NOC_RS02080
uniprot id: Q3JE49
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS03055
gene id: 323261:NOC_RS03055
uniprot id: Q3JDM1
names: Similarity
messages: Belongs to the LOG family.

323261:NOC RS14745
gene id: 323261:NOC_RS14745
uniprot id: Q3J7H0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

323261:NOC RS06070
gene id: 323261:NOC_RS06070
uniprot id: Q3JC27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

323261:NOC RS11415
gene id: 323261:NOC_RS11415
uniprot id: Q3J9A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

323261:NOC RS14005
gene id: 323261:NOC_RS14005
uniprot id: Q3J7V8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

323261:NOC RS12290
gene id: 323261:NOC_RS12290
uniprot id: Q3J8T9
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

323261:NOC RS00765
gene id: 323261:NOC_RS00765
uniprot id: Q3JEV0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

323261:NOC RS07730
gene id: 323261:NOC_RS07730
uniprot id: Q3JB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS15995
gene id: 323261:NOC_RS15995
uniprot id: Q3J6T2
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14165
gene id: 323261:NOC_RS14165
uniprot id: Q3J7S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

323261:NOC RS00790
gene id: 323261:NOC_RS00790
uniprot id: Q3JEU6
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS14235
gene id: 323261:NOC_RS14235
uniprot id: Q3J7R3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

323261:NOC RS00820
gene id: 323261:NOC_RS00820
uniprot id: Q3JEU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

323261:NOC RS12955
gene id: 323261:NOC_RS12955
uniprot id: Q3J8G2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

323261:NOC RS13990
gene id: 323261:NOC_RS13990
uniprot id: Q3J7W1
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

323261:NOC RS15360
gene id: 323261:NOC_RS15360
uniprot id: Q3J748
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

323261:NOC RS12220
gene id: 323261:NOC_RS12220
uniprot id: Q3J8V3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

323261:NOC RS16120
gene id: 323261:NOC_RS16120
uniprot id: Q3J6Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

323261:NOC RS12470
gene id: 323261:NOC_RS12470
uniprot id: Q3J8Q2
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

323261:NOC RS03380
gene id: 323261:NOC_RS03380
uniprot id: Q3JDG4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

323261:NOC RS05250
gene id: 323261:NOC_RS05250
uniprot id: Q3JCH3
names: Similarity
messages: Belongs to the histone deacetylase family.

323261:NOC RS06230
gene id: 323261:NOC_RS06230
uniprot id: Q3JC00
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

323261:NOC RS09405
gene id: 323261:NOC_RS09405
uniprot id: Q3JAD1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

323261:NOC RS05535
gene id: 323261:NOC_RS05535
uniprot id: Q3JCC4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

323261:NOC RS04860
gene id: 323261:NOC_RS04860
uniprot id: Q3JCP2
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds 8 heme c groups per subunit. One specific heme c group is called heme P460.
messages: Catalyzes the oxidation of hydroxylamine to nitrite. The electrons released in the reaction are partitioned to ammonium monooxygenase and to the respiratory chain. The immediate acceptor of electrons from HAO is cytochrome c-554.
messages: Homotrimer.
messages: Periplasm

323261:NOC RS13555
gene id: 323261:NOC_RS13555
uniprot id: Q3J846
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

323261:NOC RS11455
gene id: 323261:NOC_RS11455
uniprot id: Q3J995
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS09745
gene id: 323261:NOC_RS09745
uniprot id: Q3JA68
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

323261:NOC RS13805
gene id: 323261:NOC_RS13805
uniprot id: Q3J7Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

323261:NOC RS08270
gene id: 323261:NOC_RS08270
uniprot id: Q3JAX6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

323261:NOC RS05755
gene id: 323261:NOC_RS05755
uniprot id: Q3JC80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

323261:NOC RS12565
gene id: 323261:NOC_RS12565
uniprot id: Q3J8N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS13745
gene id: 323261:NOC_RS13745
uniprot id: Q3J810
names: Similarity
messages: Belongs to the thioredoxin family.

323261:NOC RS01480
gene id: 323261:NOC_RS01480
uniprot id: Q3JEG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

323261:NOC RS16160
gene id: 323261:NOC_RS16160
uniprot id: Q3J6Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

323261:NOC RS08325
gene id: 323261:NOC_RS08325
uniprot id: Q3JAW5
names: Subcellular Location Annotation
messages: Membrane

323261:NOC RS12635
gene id: 323261:NOC_RS12635
uniprot id: Q3J8M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

323261:NOC RS11045
gene id: 323261:NOC_RS11045
uniprot id: Q3J9H4
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

323261:NOC RS14560
gene id: 323261:NOC_RS14560
uniprot id: Q3J7K1
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

323261:NOC RS01880
gene id: 323261:NOC_RS01880
uniprot id: Q3JE88
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the RuBisCO small chain family.
messages: Heterohexadecamer of 8 large and 8 small subunits.
messages: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.
messages: The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.

323261:NOC RS12825
gene id: 323261:NOC_RS12825
uniprot id: Q3J8I7
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

323261:NOC RS09845
gene id: 323261:NOC_RS09845
uniprot id: Q3JA51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

323261:NOC RS10940
gene id: 323261:NOC_RS10940
uniprot id: Q3J9J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell inner membrane
messages: Cytoplasm

323261:NOC RS11875
gene id: 323261:NOC_RS11875
uniprot id: Q3J912
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

323261:NOC RS04395
gene id: 323261:NOC_RS04395
uniprot id: Q3JCX9
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

323261:NOC RS12665
gene id: 323261:NOC_RS12665
uniprot id: Q3J8L8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

323261:NOC RS05595
gene id: 323261:NOC_RS05595
uniprot id: Q3JCB2
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

323261:NOC RS15245
gene id: 323261:NOC_RS15245
uniprot id: Q3J772
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreF family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

323261:NOC RS13255
gene id: 323261:NOC_RS13255
uniprot id: Q3J8A5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

323261:NOC RS02170
gene id: 323261:NOC_RS02170
uniprot id: Q3JE32
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.
messages: In the N-terminal section; belongs to the transposase 2 family.

323261:NOC RS11650
gene id: 323261:NOC_RS11650
uniprot id: Q3J955
names: Similarity
messages: Belongs to the ABC transporter superfamily.

323261:NOC RS13940
gene id: 323261:NOC_RS13940
uniprot id: Q3J7X2
names: Function
names: Similarity
messages: Belongs to the PqqC family.
messages: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.