319706:G6N46 RS10385
gene id: 319706:G6N46_RS10385
uniprot id: A0A7I7ZMV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

319706:G6N46 RS06830
gene id: 319706:G6N46_RS06830
uniprot id: A0A7I7ZNR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

319706:G6N46 RS13065
gene id: 319706:G6N46_RS13065
uniprot id: A0A7I7ZQN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

319706:G6N46 RS07425
gene id: 319706:G6N46_RS07425
uniprot id: A0A7I7ZKC5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

319706:G6N46 RS19620
gene id: 319706:G6N46_RS19620
uniprot id: A0A7I7ZTB4
names: Similarity
messages: Belongs to the AccD/PCCB family.

319706:G6N46 RS01465
gene id: 319706:G6N46_RS01465
uniprot id: A0A7I7ZGK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

319706:G6N46 RS26940
gene id: 319706:G6N46_RS26940
uniprot id: A0A7I7ZXI7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.
messages: Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.

319706:G6N46 RS15905
gene id: 319706:G6N46_RS15905
uniprot id: A0A7I7ZTR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

319706:G6N46 RS09760
gene id: 319706:G6N46_RS09760
uniprot id: A0A7I7ZNJ1
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

319706:G6N46 RS21390
gene id: 319706:G6N46_RS21390
uniprot id: A0A7I7ZU38
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.

319706:G6N46 RS08010
gene id: 319706:G6N46_RS08010
uniprot id: A0A7I7ZKA2
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic ubiquitin-like protein family.
messages: Is modified by deamidation of its C-terminal glutamine to glutamate by the deamidase Dop, a prerequisite to the subsequent pupylation process.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
messages: Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.
messages: The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome.

319706:G6N46 RS22140
gene id: 319706:G6N46_RS22140
uniprot id: A0A7I7ZXD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

319706:G6N46 RS16560
gene id: 319706:G6N46_RS16560
uniprot id: A0A7I7ZSV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

319706:G6N46 RS13105
gene id: 319706:G6N46_RS13105
uniprot id: A0A7I7ZN51
names: Similarity
names: Subunit
messages: Belongs to the trans-sulfuration enzymes family.
messages: Homotetramer.

319706:G6N46 RS01790
gene id: 319706:G6N46_RS01790
uniprot id: A0A7I7ZHR1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

319706:G6N46 RS20340
gene id: 319706:G6N46_RS20340
uniprot id: A0A7I7ZWB5
names: Subcellular Location Annotation
messages: Cytoplasm

319706:G6N46 RS08765
gene id: 319706:G6N46_RS08765
uniprot id: A0A7I7ZL33
names: Function
names: Similarity
messages: Belongs to the CobT family.
messages: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).

319706:G6N46 RS09395
gene id: 319706:G6N46_RS09395
uniprot id: A0A7I7ZKZ7
names: Similarity
messages: Belongs to the MmpS family.

319706:G6N46 RS11565
gene id: 319706:G6N46_RS11565
uniprot id: A0A7I7ZRD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

319706:G6N46 RS04355
gene id: 319706:G6N46_RS04355
uniprot id: A0A7I7ZI66
names: Similarity
messages: Belongs to the IS21/IS1162 putative ATP-binding protein family.

319706:G6N46 RS02640
gene id: 319706:G6N46_RS02640
uniprot id: A0A7I7ZJG3
names: Similarity
messages: Belongs to the UPF0749 family.

319706:G6N46 RS19135
gene id: 319706:G6N46_RS19135
uniprot id: A0A7I7ZTZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

319706:G6N46 RS08725
gene id: 319706:G6N46_RS08725
uniprot id: A0A7I7ZLY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

319706:G6N46 RS17985
gene id: 319706:G6N46_RS17985
uniprot id: A0A7I7ZV05
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

319706:G6N46 RS12035
gene id: 319706:G6N46_RS12035
uniprot id: A0A7I7ZMG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

319706:G6N46 RS00375
gene id: 319706:G6N46_RS00375
uniprot id: A0A7I7ZFX9
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS24245
gene id: 319706:G6N46_RS24245
uniprot id: A0A7I7ZV89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

319706:G6N46 RS00305
gene id: 319706:G6N46_RS00305
uniprot id: A0A7I7ZJU4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS20850
gene id: 319706:G6N46_RS20850
uniprot id: A0A7I7ZVN3
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS11750
gene id: 319706:G6N46_RS11750
uniprot id: A0A7I7ZPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

319706:G6N46 RS25685
gene id: 319706:G6N46_RS25685
uniprot id: A0A7I7ZYJ9
names: Similarity
messages: Belongs to the MmpS family.

319706:G6N46 RS06120
gene id: 319706:G6N46_RS06120
uniprot id: A0A7I7ZKC2
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

319706:G6N46 RS17280
gene id: 319706:G6N46_RS17280
uniprot id: A0A7I7ZQF2
names: Similarity
messages: Belongs to the CsoR family.

319706:G6N46 RS13725
gene id: 319706:G6N46_RS13725
uniprot id: A0A7I7ZR05
names: Similarity
names: Subunit
messages: Belongs to the sigma-70 factor family. ECF subfamily.
messages: Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription.

319706:G6N46 RS13910
gene id: 319706:G6N46_RS13910
uniprot id: A0A7I7ZPQ0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS04455
gene id: 319706:G6N46_RS04455
uniprot id: A0A7I7ZIA7
names: Similarity
messages: Belongs to the band 7/mec-2 family.

319706:G6N46 RS03025
gene id: 319706:G6N46_RS03025
uniprot id: A0A7I7ZHH1
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

319706:G6N46 RS07765
gene id: 319706:G6N46_RS07765
uniprot id: A0A7I7ZK56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS24220
gene id: 319706:G6N46_RS24220
uniprot id: A0A7I7ZUF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

319706:G6N46 RS06890
gene id: 319706:G6N46_RS06890
uniprot id: A0A7I7ZME9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

319706:G6N46 RS01785
gene id: 319706:G6N46_RS01785
uniprot id: A0A7I7ZGK6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

319706:G6N46 RS00350
gene id: 319706:G6N46_RS00350
uniprot id: A0A7I7ZJV3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS03130
gene id: 319706:G6N46_RS03130
uniprot id: A0A7I7ZHL1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

319706:G6N46 RS08870
gene id: 319706:G6N46_RS08870
uniprot id: A0A7I7ZPW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

319706:G6N46 RS26790
gene id: 319706:G6N46_RS26790
uniprot id: A0A7I7ZXF5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

319706:G6N46 RS00365
gene id: 319706:G6N46_RS00365
uniprot id: A0A7I7ZIR0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS26820
gene id: 319706:G6N46_RS26820
uniprot id: A0A7I7ZW00
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

319706:G6N46 RS01310
gene id: 319706:G6N46_RS01310
uniprot id: A0A7I7ZJB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

319706:G6N46 RS23365
gene id: 319706:G6N46_RS23365
uniprot id: A0A7I7ZTZ7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

319706:G6N46 RS11285
gene id: 319706:G6N46_RS11285
uniprot id: A0A7I7ZNF9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

319706:G6N46 RS27100
gene id: 319706:G6N46_RS27100
uniprot id: A0A7I7ZZG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

319706:G6N46 RS11380
gene id: 319706:G6N46_RS11380
uniprot id: A0A7I7ZLZ7
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

319706:G6N46 RS05260
gene id: 319706:G6N46_RS05260
uniprot id: A0A7I7ZJV9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319706:G6N46 RS15900
gene id: 319706:G6N46_RS15900
uniprot id: A7BJ27
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

319706:G6N46 RS11455
gene id: 319706:G6N46_RS11455
uniprot id: A0A7I7ZNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

319706:G6N46 RS02645
gene id: 319706:G6N46_RS02645
uniprot id: A0A7I7ZH26
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

319706:G6N46 RS18050
gene id: 319706:G6N46_RS18050
uniprot id: A0A7I7ZS86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

319706:G6N46 RS01285
gene id: 319706:G6N46_RS01285
uniprot id: A0A7I7ZHF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

319706:G6N46 RS28010
gene id: 319706:G6N46_RS28010
uniprot id: A0A7I7ZWP0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319706:G6N46 RS18315
gene id: 319706:G6N46_RS18315
uniprot id: A0A7I7ZR15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

319706:G6N46 RS00735
gene id: 319706:G6N46_RS00735
uniprot id: A0A7I7ZK25
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

319706:G6N46 RS18020
gene id: 319706:G6N46_RS18020
uniprot id: A0A7I7ZQV7
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

319706:G6N46 RS16510
gene id: 319706:G6N46_RS16510
uniprot id: A0A7I7ZSU7
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

319706:G6N46 RS24140
gene id: 319706:G6N46_RS24140
uniprot id: A0A7I7ZUH0
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

319706:G6N46 RS24255
gene id: 319706:G6N46_RS24255
uniprot id: A0A7I7ZVW8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

319706:G6N46 RS02915
gene id: 319706:G6N46_RS02915
uniprot id: A0A7I7ZIL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Homooligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

319706:G6N46 RS27210
gene id: 319706:G6N46_RS27210
uniprot id: A0A7I7ZW55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

319706:G6N46 RS08685
gene id: 319706:G6N46_RS08685
uniprot id: A0A7I7ZNM9
names: Caution
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Binds 2 heme c groups covalently per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit.

319706:G6N46 RS04740
gene id: 319706:G6N46_RS04740
uniprot id: A0A7I7ZL89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

319706:G6N46 RS10140
gene id: 319706:G6N46_RS10140
uniprot id: A0A7I7ZLH9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

319706:G6N46 RS13095
gene id: 319706:G6N46_RS13095
uniprot id: A0A7I7ZQX1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

319706:G6N46 RS28150
gene id: 319706:G6N46_RS28150
uniprot id: A0A7I7ZWQ0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF2.
messages: Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.

319706:G6N46 RS27995
gene id: 319706:G6N46_RS27995
uniprot id: A0A7I7ZZ80
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS18015
gene id: 319706:G6N46_RS18015
uniprot id: A0A7I7ZQW1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

319706:G6N46 RS20665
gene id: 319706:G6N46_RS20665
uniprot id: A0A7I7ZSD1
names: Function
names: Similarity
messages: Belongs to the EgtB family.
messages: Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.

319706:G6N46 RS12385
gene id: 319706:G6N46_RS12385
uniprot id: A0A7I7ZN58
names: Cofactor
names: Function
messages: Binds 1 [3Fe-4S] cluster.
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

319706:G6N46 RS24160
gene id: 319706:G6N46_RS24160
uniprot id: A0A7I7ZVU6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

319706:G6N46 RS04915
gene id: 319706:G6N46_RS04915
uniprot id: A0A7I7ZJP9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS24130
gene id: 319706:G6N46_RS24130
uniprot id: A0A7I7ZUD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

319706:G6N46 RS14135
gene id: 319706:G6N46_RS14135
uniprot id: A0A7I7ZNI4
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS10490
gene id: 319706:G6N46_RS10490
uniprot id: A0A7I7ZM25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: Membrane

319706:G6N46 RS07480
gene id: 319706:G6N46_RS07480
uniprot id: A0A7I7ZP40
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

319706:G6N46 RS01655
gene id: 319706:G6N46_RS01655
uniprot id: A0A7I7ZHY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

319706:G6N46 RS06825
gene id: 319706:G6N46_RS06825
uniprot id: A0A7I7ZK12
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

319706:G6N46 RS23355
gene id: 319706:G6N46_RS23355
uniprot id: A0A7I7ZXA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS01685
gene id: 319706:G6N46_RS01685
uniprot id: A0A7I7ZIV7
names: Similarity
messages: Belongs to the universal stress protein A family.

319706:G6N46 RS08165
gene id: 319706:G6N46_RS08165
uniprot id: A0A7I7ZKT3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme.
messages: Feedback inhibited by histidine.

319706:G6N46 RS24475
gene id: 319706:G6N46_RS24475
uniprot id: A0A7I7ZUJ6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

319706:G6N46 RS24815
gene id: 319706:G6N46_RS24815
uniprot id: A0A7I7ZUQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD.

319706:G6N46 RS21420
gene id: 319706:G6N46_RS21420
uniprot id: A0A7I7ZUG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

319706:G6N46 RS13615
gene id: 319706:G6N46_RS13615
uniprot id: A0A7I7ZNC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

319706:G6N46 RS03830
gene id: 319706:G6N46_RS03830
uniprot id: A0A7I7ZKT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

319706:G6N46 RS17715
gene id: 319706:G6N46_RS17715
uniprot id: A0A7I7ZSB0
names: Similarity
messages: Belongs to the WXG100 family.

319706:G6N46 RS04460
gene id: 319706:G6N46_RS04460
uniprot id: A0A7I7ZKJ0
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS17620
gene id: 319706:G6N46_RS17620
uniprot id: A0A7I7ZQL8
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

319706:G6N46 RS27465
gene id: 319706:G6N46_RS27465
uniprot id: A0A7I7ZYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cutinase family.
messages: Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants. Degrades cutin, a macromolecule that forms the structure of the plant cuticle.
messages: Secreted

319706:G6N46 RS22825
gene id: 319706:G6N46_RS22825
uniprot id: A0A7I7ZTS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cell surface
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
messages: capsule
messages: cell wall

319706:G6N46 RS10665
gene id: 319706:G6N46_RS10665
uniprot id: A0A7I7ZMY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

319706:G6N46 RS07250
gene id: 319706:G6N46_RS07250
uniprot id: A0A7I7ZJW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A probable RNA-binding protein.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm

319706:G6N46 RS19570
gene id: 319706:G6N46_RS19570
uniprot id: A0A7I7ZRQ9
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

319706:G6N46 RS26800
gene id: 319706:G6N46_RS26800
uniprot id: A0A7I7ZZ97
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

319706:G6N46 RS24480
gene id: 319706:G6N46_RS24480
uniprot id: A0A7I7ZX01
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

319706:G6N46 RS22320
gene id: 319706:G6N46_RS22320
uniprot id: A0A7I7ZTD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

319706:G6N46 RS08605
gene id: 319706:G6N46_RS08605
uniprot id: A0A7I7ZMY7
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
messages: Homodimer.

319706:G6N46 RS04500
gene id: 319706:G6N46_RS04500
uniprot id: A0A7I7ZI90
names: Similarity
messages: Belongs to the peptidase C40 family.

319706:G6N46 RS07240
gene id: 319706:G6N46_RS07240
uniprot id: A0A7I7ZMM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

319706:G6N46 RS17615
gene id: 319706:G6N46_RS17615
uniprot id: A0A7I7ZT73
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

319706:G6N46 RS22740
gene id: 319706:G6N46_RS22740
uniprot id: A0A7I7ZU23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

319706:G6N46 RS19280
gene id: 319706:G6N46_RS19280
uniprot id: A0A7I7ZU25
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

319706:G6N46 RS01260
gene id: 319706:G6N46_RS01260
uniprot id: A0A7I7ZJA7
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

319706:G6N46 RS05840
gene id: 319706:G6N46_RS05840
uniprot id: A0A7I7ZLY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ChdC family. Type 2 subfamily.
messages: Fe-coproporphyrin III acts as both substrate and redox cofactor.
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate.

319706:G6N46 RS18030
gene id: 319706:G6N46_RS18030
uniprot id: A0A7I7ZQV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

319706:G6N46 RS06295
gene id: 319706:G6N46_RS06295
uniprot id: A0A7I7ZM67
names: Similarity
messages: Belongs to the PspA/IM30 family.

319706:G6N46 RS13190
gene id: 319706:G6N46_RS13190
uniprot id: A0A7I7ZPD4
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

319706:G6N46 RS12455
gene id: 319706:G6N46_RS12455
uniprot id: A0A7I7ZMS4
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

319706:G6N46 RS28020
gene id: 319706:G6N46_RS28020
uniprot id: A0A7I7ZWN6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319706:G6N46 RS21575
gene id: 319706:G6N46_RS21575
uniprot id: A0A7I7ZX15
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS13665
gene id: 319706:G6N46_RS13665
uniprot id: A0A7I7ZNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

319706:G6N46 RS23080
gene id: 319706:G6N46_RS23080
uniprot id: A0A7I7ZVH1
names: Function
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

319706:G6N46 RS08880
gene id: 319706:G6N46_RS08880
uniprot id: A0A7I7ZNL8
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS27690
gene id: 319706:G6N46_RS27690
uniprot id: A0A7I7ZXZ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

319706:G6N46 RS24230
gene id: 319706:G6N46_RS24230
uniprot id: A0A7I7ZWU7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

319706:G6N46 RS07210
gene id: 319706:G6N46_RS07210
uniprot id: A0A7I7ZM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

319706:G6N46 RS23710
gene id: 319706:G6N46_RS23710
uniprot id: A0A7I7ZWT4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

319706:G6N46 RS26925
gene id: 319706:G6N46_RS26925
uniprot id: A0A7I7ZXK1
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS16315
gene id: 319706:G6N46_RS16315
uniprot id: A0A7I7ZQD5
names: Function
names: Similarity
messages: Belongs to the Stf0 sulfotransferase family.
messages: Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S).

319706:G6N46 RS17745
gene id: 319706:G6N46_RS17745
uniprot id: A0A7I7ZQQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EccB family.
messages: Membrane

319706:G6N46 RS16305
gene id: 319706:G6N46_RS16305
uniprot id: A0A7I7ZPV4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

319706:G6N46 RS24470
gene id: 319706:G6N46_RS24470
uniprot id: A0A7I7ZUL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

319706:G6N46 RS27650
gene id: 319706:G6N46_RS27650
uniprot id: A0A7I7ZZU7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

319706:G6N46 RS24125
gene id: 319706:G6N46_RS24125
uniprot id: A0A7I7ZUD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

319706:G6N46 RS00300
gene id: 319706:G6N46_RS00300
uniprot id: A0A7I7ZGB1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS26835
gene id: 319706:G6N46_RS26835
uniprot id: A0A7I8A015
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

319706:G6N46 RS06635
gene id: 319706:G6N46_RS06635
uniprot id: A0A7I7ZKQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

319706:G6N46 RS20105
gene id: 319706:G6N46_RS20105
uniprot id: A0A7I7ZS13
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

319706:G6N46 RS05100
gene id: 319706:G6N46_RS05100
uniprot id: A0A7I7ZIM7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

319706:G6N46 RS18135
gene id: 319706:G6N46_RS18135
uniprot id: A0A7I7ZSI9
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

319706:G6N46 RS05850
gene id: 319706:G6N46_RS05850
uniprot id: A0A7I7ZJ09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS23965
gene id: 319706:G6N46_RS23965
uniprot id: A0A7I7ZXM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

319706:G6N46 RS27990
gene id: 319706:G6N46_RS27990
uniprot id: A0A7I7ZY59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

319706:G6N46 RS07360
gene id: 319706:G6N46_RS07360
uniprot id: A0A7I7ZM88
names: Subunit
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.

319706:G6N46 RS15600
gene id: 319706:G6N46_RS15600
uniprot id: A0A7I7ZTL2
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

319706:G6N46 RS09805
gene id: 319706:G6N46_RS09805
uniprot id: A0A7I7ZL66
names: Similarity
messages: Belongs to the thioesterase family.

319706:G6N46 RS05535
gene id: 319706:G6N46_RS05535
uniprot id: A0A7I7ZIV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

319706:G6N46 RS26295
gene id: 319706:G6N46_RS26295
uniprot id: A0A7I7ZY76
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

319706:G6N46 RS12740
gene id: 319706:G6N46_RS12740
uniprot id: A0A7I7ZPD2
names: Subcellular Location Annotation
messages: Secreted

319706:G6N46 RS10255
gene id: 319706:G6N46_RS10255
uniprot id: A0A7I7ZNT8
names: Similarity
messages: Belongs to the AfsR/DnrI/RedD regulatory family.

319706:G6N46 RS12665
gene id: 319706:G6N46_RS12665
uniprot id: A0A7I7ZQL9
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

319706:G6N46 RS07910
gene id: 319706:G6N46_RS07910
uniprot id: A0A7I7ZKA6
names: Similarity
messages: Belongs to the CsoR family.

319706:G6N46 RS07365
gene id: 319706:G6N46_RS07365
uniprot id: A0A7I7ZJW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

319706:G6N46 RS14680
gene id: 319706:G6N46_RS14680
uniprot id: A0A7I7ZT55
names: Similarity
messages: Belongs to the citrate synthase family.

319706:G6N46 RS26715
gene id: 319706:G6N46_RS26715
uniprot id: A0A7I7ZYA2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

319706:G6N46 RS21330
gene id: 319706:G6N46_RS21330
uniprot id: A0A7I7ZT69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

319706:G6N46 RS00030
gene id: 319706:G6N46_RS00030
uniprot id: A0A7I7ZIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

319706:G6N46 RS17585
gene id: 319706:G6N46_RS17585
uniprot id: A0A7I7ZUT2
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

319706:G6N46 RS10590
gene id: 319706:G6N46_RS10590
uniprot id: A0A7I7ZLJ5
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS20740
gene id: 319706:G6N46_RS20740
uniprot id: A0A7I7ZWJ0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

319706:G6N46 RS13000
gene id: 319706:G6N46_RS13000
uniprot id: A0A7I7ZP90
names: Cofactor
names: Similarity
messages: Belongs to the fatty acid desaturase type 2 family.
messages: Binds 2 iron ions per subunit.

319706:G6N46 RS10530
gene id: 319706:G6N46_RS10530
uniprot id: A0A7I7ZLK2
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

319706:G6N46 RS14465
gene id: 319706:G6N46_RS14465
uniprot id: A0A7I7ZWP8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

319706:G6N46 RS24115
gene id: 319706:G6N46_RS24115
uniprot id: A0A7I7ZX03
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

319706:G6N46 RS28015
gene id: 319706:G6N46_RS28015
uniprot id: A0A7I7ZZ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

319706:G6N46 RS23160
gene id: 319706:G6N46_RS23160
uniprot id: A0A7I7ZX60
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

319706:G6N46 RS07465
gene id: 319706:G6N46_RS07465
uniprot id: A0A7I7ZJZ1
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

319706:G6N46 RS13710
gene id: 319706:G6N46_RS13710
uniprot id: A0A7I7ZRH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

319706:G6N46 RS16855
gene id: 319706:G6N46_RS16855
uniprot id: A0A7I7ZRE5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS01870
gene id: 319706:G6N46_RS01870
uniprot id: A0A7I7ZGT6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

319706:G6N46 RS16540
gene id: 319706:G6N46_RS16540
uniprot id: A0A7I7ZRK3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS20600
gene id: 319706:G6N46_RS20600
uniprot id: A0A7I7ZTM5
names: Function
names: Similarity
messages: Belongs to the aspartokinase family.
messages: Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.

319706:G6N46 RS23970
gene id: 319706:G6N46_RS23970
uniprot id: A0A7I7ZUA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

319706:G6N46 RS00025
gene id: 319706:G6N46_RS00025
uniprot id: A0A7I7ZID9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division.

319706:G6N46 RS11550
gene id: 319706:G6N46_RS11550
uniprot id: A0A7I7ZM28
names: Function
names: Similarity
messages: Belongs to the threonine synthase family.
messages: Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.

319706:G6N46 RS26855
gene id: 319706:G6N46_RS26855
uniprot id: A0A7I7ZVX6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS13640
gene id: 319706:G6N46_RS13640
uniprot id: A0A7I7ZNX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

319706:G6N46 RS05640
gene id: 319706:G6N46_RS05640
uniprot id: A0A7I7ZL85
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PdxS/SNZ family.
messages: Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
messages: In the presence of PdxT, forms a dodecamer of heterodimers.

319706:G6N46 RS24165
gene id: 319706:G6N46_RS24165
uniprot id: A0A7I7ZX13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

319706:G6N46 RS08435
gene id: 319706:G6N46_RS08435
uniprot id: A0A7I7ZND1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepF family.
messages: Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

319706:G6N46 RS17890
gene id: 319706:G6N46_RS17890
uniprot id: A0A7I7ZU08
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319706:G6N46 RS08720
gene id: 319706:G6N46_RS08720
uniprot id: A0A7I7ZPU4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with subunits I, II and III to form cytochrome c oxidase.
messages: Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
messages: Cell membrane
messages: Membrane
messages: Part of cytochrome c oxidase, its function is unknown.

319706:G6N46 RS12280
gene id: 319706:G6N46_RS12280
uniprot id: A0A7I7ZMI2
names: Similarity
messages: Belongs to the HSP15 family.

319706:G6N46 RS01215
gene id: 319706:G6N46_RS01215
uniprot id: A0A7I7ZGF8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS17580
gene id: 319706:G6N46_RS17580
uniprot id: A0A7I7ZR27
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

319706:G6N46 RS03100
gene id: 319706:G6N46_RS03100
uniprot id: A0A7I7ZHX3
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

319706:G6N46 RS11465
gene id: 319706:G6N46_RS11465
uniprot id: A0A7I7ZRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

319706:G6N46 RS17635
gene id: 319706:G6N46_RS17635
uniprot id: A0A7I7ZUU3
names: Similarity
messages: Belongs to the EccE family.

319706:G6N46 RS13035
gene id: 319706:G6N46_RS13035
uniprot id: A0A7I7ZNJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

319706:G6N46 RS23980
gene id: 319706:G6N46_RS23980
uniprot id: A0A7I7ZWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

319706:G6N46 RS16320
gene id: 319706:G6N46_RS16320
uniprot id: A0A7I7ZU05
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

319706:G6N46 RS26725
gene id: 319706:G6N46_RS26725
uniprot id: A0A7I7ZXF6
names: Similarity
messages: Belongs to the AccD/PCCB family.

319706:G6N46 RS11450
gene id: 319706:G6N46_RS11450
uniprot id: A0A7I7ZM06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

319706:G6N46 RS24215
gene id: 319706:G6N46_RS24215
uniprot id: A0A7I7ZXS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

319706:G6N46 RS26815
gene id: 319706:G6N46_RS26815
uniprot id: A0A7I7ZYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

319706:G6N46 RS08430
gene id: 319706:G6N46_RS08430
uniprot id: A0A7I7ZLS1
names: Similarity
messages: Belongs to the YggT family.

319706:G6N46 RS00475
gene id: 319706:G6N46_RS00475
uniprot id: A0A7I7ZG03
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

319706:G6N46 RS14470
gene id: 319706:G6N46_RS14470
uniprot id: A0A7I7ZRE8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

319706:G6N46 RS13060
gene id: 319706:G6N46_RS13060
uniprot id: A0A7I7ZN16
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS03810
gene id: 319706:G6N46_RS03810
uniprot id: A0A7I7ZIA6
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS25625
gene id: 319706:G6N46_RS25625
uniprot id: A0A7I7ZWP8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

319706:G6N46 RS28005
gene id: 319706:G6N46_RS28005
uniprot id: A0A7I7ZWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319706:G6N46 RS24155
gene id: 319706:G6N46_RS24155
uniprot id: A0A7I7ZYG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

319706:G6N46 RS28170
gene id: 319706:G6N46_RS28170
uniprot id: A0A7I7ZIJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

319706:G6N46 RS16310
gene id: 319706:G6N46_RS16310
uniprot id: A0A7I7ZRE4
names: Similarity
messages: Belongs to the sulfatase family.

319706:G6N46 RS07725
gene id: 319706:G6N46_RS07725
uniprot id: A0A7I7ZK36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

319706:G6N46 RS24225
gene id: 319706:G6N46_RS24225
uniprot id: A0A7I7ZUE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

319706:G6N46 RS24285
gene id: 319706:G6N46_RS24285
uniprot id: A0A7I7ZUJ9
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

319706:G6N46 RS01875
gene id: 319706:G6N46_RS01875
uniprot id: A0A7I7ZGV4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

319706:G6N46 RS09975
gene id: 319706:G6N46_RS09975
uniprot id: A0A7I7ZML6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

319706:G6N46 RS07475
gene id: 319706:G6N46_RS07475
uniprot id: A0A7I7ZKD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial histone-like protein family. Long actinobacterial subfamily.
messages: nucleoid

319706:G6N46 RS28000
gene id: 319706:G6N46_RS28000
uniprot id: A0A7I8A036
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319706:G6N46 RS03775
gene id: 319706:G6N46_RS03775
uniprot id: A0A7I7ZJ11
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

319706:G6N46 RS08875
gene id: 319706:G6N46_RS08875
uniprot id: A0A7I7ZM14
names: Similarity
messages: Belongs to the darcynin family.

319706:G6N46 RS22745
gene id: 319706:G6N46_RS22745
uniprot id: A0A7I7ZXR2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

319706:G6N46 RS08775
gene id: 319706:G6N46_RS08775
uniprot id: A0A7I7ZLZ3
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

319706:G6N46 RS07485
gene id: 319706:G6N46_RS07485
uniprot id: A0A7I7ZL60
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

319706:G6N46 RS08850
gene id: 319706:G6N46_RS08850
uniprot id: A0A7I7ZN31
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

319706:G6N46 RS03060
gene id: 319706:G6N46_RS03060
uniprot id: A0A7I7ZIN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TerC family.
messages: Membrane

319706:G6N46 RS28050
gene id: 319706:G6N46_RS28050
uniprot id: A0A7I8A046
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319706:G6N46 RS23750
gene id: 319706:G6N46_RS23750
uniprot id: A0A7I7ZUU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

319706:G6N46 RS28030
gene id: 319706:G6N46_RS28030
uniprot id: A0A7I7ZXG8
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

319706:G6N46 RS06950
gene id: 319706:G6N46_RS06950
uniprot id: A0A7I7ZJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

319706:G6N46 RS03935
gene id: 319706:G6N46_RS03935
uniprot id: A0A7I7ZKV2
names: Similarity
messages: Belongs to the asp23 family.

319706:G6N46 RS19450
gene id: 319706:G6N46_RS19450
uniprot id: A0A7I7ZUE4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

319706:G6N46 RS08215
gene id: 319706:G6N46_RS08215
uniprot id: A0A7I7ZKU4
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

319706:G6N46 RS11540
gene id: 319706:G6N46_RS11540
uniprot id: A0A7I7ZM58
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS24460
gene id: 319706:G6N46_RS24460
uniprot id: A0A7I7ZX67
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

319706:G6N46 RS24250
gene id: 319706:G6N46_RS24250
uniprot id: A0A7I7ZYI3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

319706:G6N46 RS00140
gene id: 319706:G6N46_RS00140
uniprot id: A0A7I7ZFK5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

319706:G6N46 RS11475
gene id: 319706:G6N46_RS11475
uniprot id: A0A7I7ZPZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

319706:G6N46 RS01440
gene id: 319706:G6N46_RS01440
uniprot id: A0A7I7ZGZ6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

319706:G6N46 RS13915
gene id: 319706:G6N46_RS13915
uniprot id: A0A7I7ZRD1
names: Similarity
messages: Belongs to the AccD/PCCB family.

319706:G6N46 RS11515
gene id: 319706:G6N46_RS11515
uniprot id: A0A7I7ZRC6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

319706:G6N46 RS05575
gene id: 319706:G6N46_RS05575
uniprot id: A0A7I7ZLS2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

319706:G6N46 RS04925
gene id: 319706:G6N46_RS04925
uniprot id: A0A7I7ZMM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

319706:G6N46 RS13700
gene id: 319706:G6N46_RS13700
uniprot id: A0A7I7ZPL6
names: Similarity
messages: Belongs to the transglycosylase family. Rpf subfamily.

319706:G6N46 RS13775
gene id: 319706:G6N46_RS13775
uniprot id: A0A7I7ZR16
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

319706:G6N46 RS22670
gene id: 319706:G6N46_RS22670
uniprot id: A0A7I7ZTL0
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS08550
gene id: 319706:G6N46_RS08550
uniprot id: A0A7I7ZKK5
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

319706:G6N46 RS21085
gene id: 319706:G6N46_RS21085
uniprot id: A0A7I7ZWP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

319706:G6N46 RS18730
gene id: 319706:G6N46_RS18730
uniprot id: A0A7I7ZU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

319706:G6N46 RS19470
gene id: 319706:G6N46_RS19470
uniprot id: A0A7I7ZRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

319706:G6N46 RS09720
gene id: 319706:G6N46_RS09720
uniprot id: A0A7I7ZMI5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

319706:G6N46 RS04005
gene id: 319706:G6N46_RS04005
uniprot id: A0A7I7ZJ67
names: Similarity
messages: Belongs to the universal stress protein A family.

319706:G6N46 RS01535
gene id: 319706:G6N46_RS01535
uniprot id: A0A7I7ZGF3
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS11495
gene id: 319706:G6N46_RS11495
uniprot id: A0A7I7ZPH5
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS13930
gene id: 319706:G6N46_RS13930
uniprot id: A0A7I7ZNH6
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

319706:G6N46 RS26930
gene id: 319706:G6N46_RS26930
uniprot id: A0A7I7ZWS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

319706:G6N46 RS04775
gene id: 319706:G6N46_RS04775
uniprot id: A0A7I7ZMK1
names: Function
names: Similarity
messages: Belongs to the WhiA family.
messages: Involved in cell division and chromosome segregation.

319706:G6N46 RS06955
gene id: 319706:G6N46_RS06955
uniprot id: A0A7I7ZJP2
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

319706:G6N46 RS08900
gene id: 319706:G6N46_RS08900
uniprot id: A0A7I7ZN39
names: Similarity
messages: Belongs to the glutamine synthetase family.

319706:G6N46 RS06515
gene id: 319706:G6N46_RS06515
uniprot id: A0A7I7ZJE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

319706:G6N46 RS26660
gene id: 319706:G6N46_RS26660
uniprot id: A0A7I7ZVU7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

319706:G6N46 RS24135
gene id: 319706:G6N46_RS24135
uniprot id: A0A7I7ZWS6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

319706:G6N46 RS17630
gene id: 319706:G6N46_RS17630
uniprot id: A0A7I7ZR36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Cell membrane
messages: Membrane

319706:G6N46 RS20015
gene id: 319706:G6N46_RS20015
uniprot id: A0A7I7ZUF5
names: Similarity
messages: Belongs to the MmpS family.

319706:G6N46 RS15450
gene id: 319706:G6N46_RS15450
uniprot id: A0A7I7ZTI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

319706:G6N46 RS17085
gene id: 319706:G6N46_RS17085
uniprot id: A0A7I7ZRX0
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

319706:G6N46 RS21215
gene id: 319706:G6N46_RS21215
uniprot id: A0A7I7ZV24
names: Similarity
messages: Belongs to the UPF0145 family.

319706:G6N46 RS27085
gene id: 319706:G6N46_RS27085
uniprot id: A0A7I8A066
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

319706:G6N46 RS05095
gene id: 319706:G6N46_RS05095
uniprot id: A0A7I7ZIK7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS22625
gene id: 319706:G6N46_RS22625
uniprot id: A0A7I7ZVY0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes.

319706:G6N46 RS06875
gene id: 319706:G6N46_RS06875
uniprot id: A0A7I7ZK23
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

319706:G6N46 RS16935
gene id: 319706:G6N46_RS16935
uniprot id: A0A7I7ZQ81
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319706:G6N46 RS05555
gene id: 319706:G6N46_RS05555
uniprot id: A0A7I7ZJ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

319706:G6N46 RS15290
gene id: 319706:G6N46_RS15290
uniprot id: A0A7I7ZQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

319706:G6N46 RS10080
gene id: 319706:G6N46_RS10080
uniprot id: A0A7I7ZMN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

319706:G6N46 RS08510
gene id: 319706:G6N46_RS08510
uniprot id: A0A7I7ZKJ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

319706:G6N46 RS05635
gene id: 319706:G6N46_RS05635
uniprot id: A0A7I7ZIW6
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

319706:G6N46 RS12710
gene id: 319706:G6N46_RS12710
uniprot id: A0A7I7ZQN0
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS08145
gene id: 319706:G6N46_RS08145
uniprot id: A0A7I7ZKD1
names: Similarity
messages: Belongs to the AHA1 family.

319706:G6N46 RS12745
gene id: 319706:G6N46_RS12745
uniprot id: A0A7I7ZNC8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS08425
gene id: 319706:G6N46_RS08425
uniprot id: A0A7I7ZPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DivIVA family.
messages: Cytoplasm

319706:G6N46 RS06165
gene id: 319706:G6N46_RS06165
uniprot id: A0A7I7ZJ75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

319706:G6N46 RS17975
gene id: 319706:G6N46_RS17975
uniprot id: A0A7I7ZSF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrgA family.
messages: Cell membrane
messages: Involved in cell division.

319706:G6N46 RS24955
gene id: 319706:G6N46_RS24955
uniprot id: A0A7I7ZUW2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.
messages: Belongs to the WhiB family.
messages: Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.
messages: Cytoplasm
messages: The Fe-S cluster can be nitrosylated by nitric oxide (NO).
messages: Upon Fe-S cluster removal intramolecular disulfide bonds are formed.

319706:G6N46 RS08855
gene id: 319706:G6N46_RS08855
uniprot id: A0A7I7ZKQ5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

319706:G6N46 RS21475
gene id: 319706:G6N46_RS21475
uniprot id: A0A7I7ZT98
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

319706:G6N46 RS06000
gene id: 319706:G6N46_RS06000
uniprot id: A0A7I7ZJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

319706:G6N46 RS21765
gene id: 319706:G6N46_RS21765
uniprot id: A0A7I7ZT19
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319706:G6N46 RS17575
gene id: 319706:G6N46_RS17575
uniprot id: A0A7I7ZS79
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319706:G6N46 RS18250
gene id: 319706:G6N46_RS18250
uniprot id: A0A7I7ZSB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

319706:G6N46 RS10245
gene id: 319706:G6N46_RS10245
uniprot id: A0A7I7ZLJ6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

319706:G6N46 RS03290
gene id: 319706:G6N46_RS03290
uniprot id: A0A7I7ZIU7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Probable amino-acid or metabolite transport protein.

319706:G6N46 RS16370
gene id: 319706:G6N46_RS16370
uniprot id: A0A7I7ZU17
names: Similarity
messages: Belongs to the WXG100 family.

319706:G6N46 RS00505
gene id: 319706:G6N46_RS00505
uniprot id: A0A7I7ZIM8
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Electron transport system for the ribonucleotide reductase system NrdEF.

319706:G6N46 RS10480
gene id: 319706:G6N46_RS10480
uniprot id: A0A7I7ZLH7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

319706:G6N46 RS21175
gene id: 319706:G6N46_RS21175
uniprot id: A0A7I7ZUA4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

319706:G6N46 RS00810
gene id: 319706:G6N46_RS00810
uniprot id: A0A7I7ZG74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

319706:G6N46 RS07230
gene id: 319706:G6N46_RS07230
uniprot id: A0A7I7ZNZ0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

319706:G6N46 RS08480
gene id: 319706:G6N46_RS08480
uniprot id: A0A7I7ZLT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

319706:G6N46 RS08760
gene id: 319706:G6N46_RS08760
uniprot id: A0A7I7ZM12
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

319706:G6N46 RS26065
gene id: 319706:G6N46_RS26065
uniprot id: A0A7I7ZVG7
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS22005
gene id: 319706:G6N46_RS22005
uniprot id: A0A7I7ZVT9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS24450
gene id: 319706:G6N46_RS24450
uniprot id: A0A7I7ZW09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

319706:G6N46 RS28080
gene id: 319706:G6N46_RS28080
uniprot id: A0A7I7ZXH7
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

319706:G6N46 RS28580
gene id: 319706:G6N46_RS28580
uniprot id: A0A7I7ZIG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

319706:G6N46 RS12210
gene id: 319706:G6N46_RS12210
uniprot id: A0A7I7ZQE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

319706:G6N46 RS09715
gene id: 319706:G6N46_RS09715
uniprot id: A0A7I7ZL39
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS23235
gene id: 319706:G6N46_RS23235
uniprot id: A0A7I7ZVJ7
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

319706:G6N46 RS21775
gene id: 319706:G6N46_RS21775
uniprot id: A0A7I7ZVE2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

319706:G6N46 RS09245
gene id: 319706:G6N46_RS09245
uniprot id: A0A7I7ZKX8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Acyl carrier protein involved in meromycolate extension.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

319706:G6N46 RS25580
gene id: 319706:G6N46_RS25580
uniprot id: A0A7I7ZWP8
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

319706:G6N46 RS24260
gene id: 319706:G6N46_RS24260
uniprot id: A0A7I7ZX31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

319706:G6N46 RS10605
gene id: 319706:G6N46_RS10605
uniprot id: A0A7I7ZQV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

319706:G6N46 RS17750
gene id: 319706:G6N46_RS17750
uniprot id: A0A7I7ZQQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbxX/CfxQ family.
messages: Cytoplasm

319706:G6N46 RS03770
gene id: 319706:G6N46_RS03770
uniprot id: A0A7I7ZM11
names: Function
names: Similarity
messages: Belongs to the MerB family.
messages: Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate. One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.

319706:G6N46 RS28045
gene id: 319706:G6N46_RS28045
uniprot id: A0A7I7ZZ90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

319706:G6N46 RS12020
gene id: 319706:G6N46_RS12020
uniprot id: A0A7I7ZQA6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

319706:G6N46 RS15390
gene id: 319706:G6N46_RS15390
uniprot id: A0A7I7ZQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

319706:G6N46 RS01005
gene id: 319706:G6N46_RS01005
uniprot id: A0A7I7ZIY6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS06435
gene id: 319706:G6N46_RS06435
uniprot id: A0A7I7ZKJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

319706:G6N46 RS15365
gene id: 319706:G6N46_RS15365
uniprot id: A0A7I7ZSF4
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

319706:G6N46 RS21145
gene id: 319706:G6N46_RS21145
uniprot id: A0A7I7ZVA8
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

319706:G6N46 RS11555
gene id: 319706:G6N46_RS11555
uniprot id: A0A7I7ZNM3
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

319706:G6N46 RS11525
gene id: 319706:G6N46_RS11525
uniprot id: A0A7I7ZQ08
names: Similarity
messages: Belongs to the YciI family.

319706:G6N46 RS26555
gene id: 319706:G6N46_RS26555
uniprot id: A0A7I7ZVR8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

319706:G6N46 RS10525
gene id: 319706:G6N46_RS10525
uniprot id: A0A7I7ZLN5
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Could possibly oxidize fatty acids using specific components.

319706:G6N46 RS11480
gene id: 319706:G6N46_RS11480
uniprot id: A0A7I7ZQ77
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

319706:G6N46 RS13715
gene id: 319706:G6N46_RS13715
uniprot id: A0A7I7ZNF7
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

319706:G6N46 RS15610
gene id: 319706:G6N46_RS15610
uniprot id: A0A7I7ZS93
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

319706:G6N46 RS13290
gene id: 319706:G6N46_RS13290
uniprot id: A0A7I7ZPF0
names: Subcellular Location Annotation
messages: Cytoplasm

319706:G6N46 RS27660
gene id: 319706:G6N46_RS27660
uniprot id: A0A7I7ZWE2
names: Similarity
messages: Belongs to the F420H(2)-dependent quinone reductase family.

319706:G6N46 RS20440
gene id: 319706:G6N46_RS20440
uniprot id: A0A7I7ZTS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

319706:G6N46 RS04780
gene id: 319706:G6N46_RS04780
uniprot id: A0A7I7ZJL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

319706:G6N46 RS19100
gene id: 319706:G6N46_RS19100
uniprot id: A0A7I7ZRZ2
names: Cofactor
names: Domain
names: Function
names: Similarity
messages: Belongs to the nitrobindin family.
messages: Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.
messages: Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.
messages: Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.

319706:G6N46 RS20890
gene id: 319706:G6N46_RS20890
uniprot id: A0A7I7ZTT4
names: Subcellular Location Annotation
messages: Cytoplasm

319706:G6N46 RS28025
gene id: 319706:G6N46_RS28025
uniprot id: A0A7I7ZYA1
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

319706:G6N46 RS20805
gene id: 319706:G6N46_RS20805
uniprot id: A0A7I7ZVM5
names: Subcellular Location Annotation
messages: Membrane

319706:G6N46 RS24625
gene id: 319706:G6N46_RS24625
uniprot id: A0A7I7ZX28
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

319706:G6N46 RS15530
gene id: 319706:G6N46_RS15530
uniprot id: A0A7I7ZS07
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

319706:G6N46 RS05605
gene id: 319706:G6N46_RS05605
uniprot id: A0A7I7ZJ88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

319706:G6N46 RS27095
gene id: 319706:G6N46_RS27095
uniprot id: A0A7I7ZYN2
names: Similarity
messages: Belongs to the long-chain O-acyltransferase family.

319706:G6N46 RS07245
gene id: 319706:G6N46_RS07245
uniprot id: A0A7I7ZMS3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

319706:G6N46 RS10585
gene id: 319706:G6N46_RS10585
uniprot id: A0A7I7ZNZ8
names: Similarity
messages: Belongs to the MmpS family.

319706:G6N46 RS10135
gene id: 319706:G6N46_RS10135
uniprot id: A0A7I7ZPG4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

319706:G6N46 RS14045
gene id: 319706:G6N46_RS14045
uniprot id: A0A7I7ZP55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

319706:G6N46 RS08920
gene id: 319706:G6N46_RS08920
uniprot id: A0A7I7ZPX6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

319706:G6N46 RS09680
gene id: 319706:G6N46_RS09680
uniprot id: A0A7I7ZQC0
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

319706:G6N46 RS24980
gene id: 319706:G6N46_RS24980
uniprot id: A0A7I7ZVN8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.