314260:PB2503 RS07190
gene id: 314260:PB2503_RS07190
uniprot id: E0TGI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

314260:PB2503 RS12605
gene id: 314260:PB2503_RS12605
uniprot id: E0TGQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

314260:PB2503 RS03865
gene id: 314260:PB2503_RS03865
uniprot id: E0TEQ8
names: Similarity
messages: Belongs to the SCO1/2 family.

314260:PB2503 RS12795
gene id: 314260:PB2503_RS12795
uniprot id: E0TGU7
names: Similarity
messages: Belongs to the Gfa family.

314260:PB2503 RS00275
gene id: 314260:PB2503_RS00275
uniprot id: E0TB26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

314260:PB2503 RS12210
gene id: 314260:PB2503_RS12210
uniprot id: E0TFM7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02185
gene id: 314260:PB2503_RS02185
uniprot id: E0TCL8
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

314260:PB2503 RS10610
gene id: 314260:PB2503_RS10610
uniprot id: E0TIG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS09690
gene id: 314260:PB2503_RS09690
uniprot id: E0TFY3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

314260:PB2503 RS10485
gene id: 314260:PB2503_RS10485
uniprot id: E0THW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

314260:PB2503 RS06395
gene id: 314260:PB2503_RS06395
uniprot id: E0TE70
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

314260:PB2503 RS12340
gene id: 314260:PB2503_RS12340
uniprot id: E0TG41
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS06610
gene id: 314260:PB2503_RS06610
uniprot id: E0TEB3
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

314260:PB2503 RS08880
gene id: 314260:PB2503_RS08880
uniprot id: E0TDB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

314260:PB2503 RS06560
gene id: 314260:PB2503_RS06560
uniprot id: E0TEA3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

314260:PB2503 RS04480
gene id: 314260:PB2503_RS04480
uniprot id: E0TFQ1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS00575
gene id: 314260:PB2503_RS00575
uniprot id: E0TB92
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS00770
gene id: 314260:PB2503_RS00770
uniprot id: E0TBC9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

314260:PB2503 RS07815
gene id: 314260:PB2503_RS07815
uniprot id: E0TID8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

314260:PB2503 RS01120
gene id: 314260:PB2503_RS01120
uniprot id: E0TBM2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS10055
gene id: 314260:PB2503_RS10055
uniprot id: E0TGP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

314260:PB2503 RS02830
gene id: 314260:PB2503_RS02830
uniprot id: E0TDH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

314260:PB2503 RS03400
gene id: 314260:PB2503_RS03400
uniprot id: E0TE28
names: Similarity
messages: Belongs to the DinB family.

314260:PB2503 RS09530
gene id: 314260:PB2503_RS09530
uniprot id: E0TEX6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

314260:PB2503 RS07740
gene id: 314260:PB2503_RS07740
uniprot id: E0TIC2
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

314260:PB2503 RS10470
gene id: 314260:PB2503_RS10470
uniprot id: E0THW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

314260:PB2503 RS06805
gene id: 314260:PB2503_RS06805
uniprot id: E0TEV5
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

314260:PB2503 RS03970
gene id: 314260:PB2503_RS03970
uniprot id: E0TES9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

314260:PB2503 RS12725
gene id: 314260:PB2503_RS12725
uniprot id: E0TGT3
names: Similarity
messages: Belongs to the TrpC family.

314260:PB2503 RS13765
gene id: 314260:PB2503_RS13765
uniprot id: E0TEK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

314260:PB2503 RS10480
gene id: 314260:PB2503_RS10480
uniprot id: E0THW4
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

314260:PB2503 RS10415
gene id: 314260:PB2503_RS10415
uniprot id: E0THV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

314260:PB2503 RS04745
gene id: 314260:PB2503_RS04745
uniprot id: E0TFV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

314260:PB2503 RS08630
gene id: 314260:PB2503_RS08630
uniprot id: E0TCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

314260:PB2503 RS00305
gene id: 314260:PB2503_RS00305
uniprot id: E0TB32
names: Similarity
messages: Belongs to the Dps family.

314260:PB2503 RS01480
gene id: 314260:PB2503_RS01480
uniprot id: E0TBX5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

314260:PB2503 RS02170
gene id: 314260:PB2503_RS02170
uniprot id: E0TCL5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

314260:PB2503 RS10670
gene id: 314260:PB2503_RS10670
uniprot id: E0TC38
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

314260:PB2503 RS13490
gene id: 314260:PB2503_RS13490
uniprot id: E0TIJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

314260:PB2503 RS02635
gene id: 314260:PB2503_RS02635
uniprot id: E0TD38
names: Function
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
messages: Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.

314260:PB2503 RS05710
gene id: 314260:PB2503_RS05710
uniprot id: E0THL4
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

314260:PB2503 RS10075
gene id: 314260:PB2503_RS10075
uniprot id: E0TH88
names: Cofactor
messages: Binds 1 heme c group covalently per subunit.

314260:PB2503 RS02505
gene id: 314260:PB2503_RS02505
uniprot id: E0TD12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

314260:PB2503 RS11125
gene id: 314260:PB2503_RS11125
uniprot id: E0TDF5
names: Similarity
messages: Belongs to the peptidase S8 family.

314260:PB2503 RS05375
gene id: 314260:PB2503_RS05375
uniprot id: E0TGZ8
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

314260:PB2503 RS06215
gene id: 314260:PB2503_RS06215
uniprot id: E0TI70
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

314260:PB2503 RS11435
gene id: 314260:PB2503_RS11435
uniprot id: E0TEH0
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

314260:PB2503 RS00360
gene id: 314260:PB2503_RS00360
uniprot id: E0TB43
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS02540
gene id: 314260:PB2503_RS02540
uniprot id: E0TD19
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

314260:PB2503 RS07610
gene id: 314260:PB2503_RS07610
uniprot id: E0THS3
names: Similarity
messages: Belongs to the peptidase C40 family.

314260:PB2503 RS01475
gene id: 314260:PB2503_RS01475
uniprot id: E0TBX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

314260:PB2503 RS09005
gene id: 314260:PB2503_RS09005
uniprot id: E0TDD9
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS06230
gene id: 314260:PB2503_RS06230
uniprot id: E0TI73
names: Similarity
messages: Belongs to the peptidase U62 family.

314260:PB2503 RS00345
gene id: 314260:PB2503_RS00345
uniprot id: E0TB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

314260:PB2503 RS12565
gene id: 314260:PB2503_RS12565
uniprot id: E0TGQ0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

314260:PB2503 RS10080
gene id: 314260:PB2503_RS10080
uniprot id: E0TH89
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Homohexamer. Dimer of a homotrimer.

314260:PB2503 RS13230
gene id: 314260:PB2503_RS13230
uniprot id: E0THZ0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS12780
gene id: 314260:PB2503_RS12780
uniprot id: E0TGU4
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

314260:PB2503 RS01680
gene id: 314260:PB2503_RS01680
uniprot id: E0TC74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

314260:PB2503 RS04770
gene id: 314260:PB2503_RS04770
uniprot id: E0TG82
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS06820
gene id: 314260:PB2503_RS06820
uniprot id: E0TFC9
names: Subcellular Location Annotation
messages: Cell inner membrane

314260:PB2503 RS02705
gene id: 314260:PB2503_RS02705
uniprot id: E0TD51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

314260:PB2503 RS01490
gene id: 314260:PB2503_RS01490
uniprot id: E0TBX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

314260:PB2503 RS00490
gene id: 314260:PB2503_RS00490
uniprot id: E0TB75
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS10845
gene id: 314260:PB2503_RS10845
uniprot id: E0TCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS00675
gene id: 314260:PB2503_RS00675
uniprot id: E0TBB0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

314260:PB2503 RS00370
gene id: 314260:PB2503_RS00370
uniprot id: E0TB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0053 family. Hemolysin C subfamily.
messages: Membrane

314260:PB2503 RS12640
gene id: 314260:PB2503_RS12640
uniprot id: E0TGR6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

314260:PB2503 RS05120
gene id: 314260:PB2503_RS05120
uniprot id: E0TGF0
names: Similarity
messages: Belongs to the ParB family.

314260:PB2503 RS03470
gene id: 314260:PB2503_RS03470
uniprot id: E0TE42
names: Similarity
messages: Belongs to the peptidase C40 family.

314260:PB2503 RS04905
gene id: 314260:PB2503_RS04905
uniprot id: E0TGA9
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS00265
gene id: 314260:PB2503_RS00265
uniprot id: E0TB24
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS05965
gene id: 314260:PB2503_RS05965
uniprot id: E0THR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

314260:PB2503 RS07320
gene id: 314260:PB2503_RS07320
uniprot id: E0TGK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

314260:PB2503 RS00870
gene id: 314260:PB2503_RS00870
uniprot id: E0TBH5
names: Cofactor
names: Similarity
messages: Belongs to the class-II DAHP synthase family.
messages: Binds 1 divalent cation per subunit. The enzyme is active with manganese, cobalt or cadmium ions.

314260:PB2503 RS12690
gene id: 314260:PB2503_RS12690
uniprot id: E0TGS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

314260:PB2503 RS13140
gene id: 314260:PB2503_RS13140
uniprot id: E0THW9
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08115
gene id: 314260:PB2503_RS08115
uniprot id: E0TBR0
names: Similarity
messages: Belongs to the GSP N family.

314260:PB2503 RS02860
gene id: 314260:PB2503_RS02860
uniprot id: E0TDI4
names: Similarity
messages: Belongs to the UPF0758 family.

314260:PB2503 RS03065
gene id: 314260:PB2503_RS03065
uniprot id: E0TDM5
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

314260:PB2503 RS11485
gene id: 314260:PB2503_RS11485
uniprot id: E0TEI0
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

314260:PB2503 RS03130
gene id: 314260:PB2503_RS03130
uniprot id: E0TDN8
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

314260:PB2503 RS01920
gene id: 314260:PB2503_RS01920
uniprot id: E0TCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

314260:PB2503 RS08125
gene id: 314260:PB2503_RS08125
uniprot id: E0TBR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

314260:PB2503 RS01640
gene id: 314260:PB2503_RS01640
uniprot id: E0TC66
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

314260:PB2503 RS12625
gene id: 314260:PB2503_RS12625
uniprot id: E0TGR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS02920
gene id: 314260:PB2503_RS02920
uniprot id: E0TDJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

314260:PB2503 RS07665
gene id: 314260:PB2503_RS07665
uniprot id: E0TIA7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
messages: Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.

314260:PB2503 RS03250
gene id: 314260:PB2503_RS03250
uniprot id: E0TDZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS06165
gene id: 314260:PB2503_RS06165
uniprot id: E0TI59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmE/CycJ family.
messages: Cell inner membrane
messages: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.

314260:PB2503 RS01155
gene id: 314260:PB2503_RS01155
uniprot id: E0TBM9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

314260:PB2503 RS04590
gene id: 314260:PB2503_RS04590
uniprot id: E0TFS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS11390
gene id: 314260:PB2503_RS11390
uniprot id: E0TDY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

314260:PB2503 RS06085
gene id: 314260:PB2503_RS06085
uniprot id: E0TI43
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS10550
gene id: 314260:PB2503_RS10550
uniprot id: E0TIF2
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

314260:PB2503 RS10815
gene id: 314260:PB2503_RS10815
uniprot id: E0TCG8
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

314260:PB2503 RS04705
gene id: 314260:PB2503_RS04705
uniprot id: E0TFU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

314260:PB2503 RS11220
gene id: 314260:PB2503_RS11220
uniprot id: E0TDV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

314260:PB2503 RS09190
gene id: 314260:PB2503_RS09190
uniprot id: E0TDT4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

314260:PB2503 RS02650
gene id: 314260:PB2503_RS02650
uniprot id: E0TD41
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

314260:PB2503 RS08985
gene id: 314260:PB2503_RS08985
uniprot id: E0TDD5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

314260:PB2503 RS05825
gene id: 314260:PB2503_RS05825
uniprot id: E0THN6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS08850
gene id: 314260:PB2503_RS08850
uniprot id: E0TDA9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

314260:PB2503 RS08590
gene id: 314260:PB2503_RS08590
uniprot id: E0TCU1
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

314260:PB2503 RS06355
gene id: 314260:PB2503_RS06355
uniprot id: E0TI98
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS09050
gene id: 314260:PB2503_RS09050
uniprot id: E0TDQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

314260:PB2503 RS11380
gene id: 314260:PB2503_RS11380
uniprot id: E0TDY2
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS11750
gene id: 314260:PB2503_RS11750
uniprot id: E0TF20
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS06180
gene id: 314260:PB2503_RS06180
uniprot id: E0TI63
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Multidrug efflux pump.

314260:PB2503 RS04060
gene id: 314260:PB2503_RS04060
uniprot id: E0TF62
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

314260:PB2503 RS04425
gene id: 314260:PB2503_RS04425
uniprot id: E0TFP0
names: Cofactor
messages: Can also use Mn(2+) ion.

314260:PB2503 RS09210
gene id: 314260:PB2503_RS09210
uniprot id: E0TDT8
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

314260:PB2503 RS03365
gene id: 314260:PB2503_RS03365
uniprot id: E0TE21
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

314260:PB2503 RS08895
gene id: 314260:PB2503_RS08895
uniprot id: E0TDB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

314260:PB2503 RS05990
gene id: 314260:PB2503_RS05990
uniprot id: E0TI24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

314260:PB2503 RS12035
gene id: 314260:PB2503_RS12035
uniprot id: E0TFK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

314260:PB2503 RS11020
gene id: 314260:PB2503_RS11020
uniprot id: E0TCX8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

314260:PB2503 RS09655
gene id: 314260:PB2503_RS09655
uniprot id: E0TFH1
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02095
gene id: 314260:PB2503_RS02095
uniprot id: E0TCK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

314260:PB2503 RS10320
gene id: 314260:PB2503_RS10320
uniprot id: E0THT4
names: Similarity
messages: Belongs to the DprA/Smf family.

314260:PB2503 RS12200
gene id: 314260:PB2503_RS12200
uniprot id: E0TFM5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

314260:PB2503 RS10325
gene id: 314260:PB2503_RS10325
uniprot id: E0THT5
names: Similarity
names: Subunit
messages: Belongs to the P(II) protein family.
messages: Homotrimer.

314260:PB2503 RS06635
gene id: 314260:PB2503_RS06635
uniprot id: E0TEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell inner membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

314260:PB2503 RS05245
gene id: 314260:PB2503_RS05245
uniprot id: E0TGX7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS09945
gene id: 314260:PB2503_RS09945
uniprot id: E0TGM2
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS09505
gene id: 314260:PB2503_RS09505
uniprot id: E0TEX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

314260:PB2503 RS05275
gene id: 314260:PB2503_RS05275
uniprot id: E0TGY3
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

314260:PB2503 RS02780
gene id: 314260:PB2503_RS02780
uniprot id: E0TD65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS08780
gene id: 314260:PB2503_RS08780
uniprot id: E0TD94
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS04315
gene id: 314260:PB2503_RS04315
uniprot id: E0TFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

314260:PB2503 RS05800
gene id: 314260:PB2503_RS05800
uniprot id: E0THN1
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

314260:PB2503 RS00580
gene id: 314260:PB2503_RS00580
uniprot id: E0TB93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

314260:PB2503 RS11300
gene id: 314260:PB2503_RS11300
uniprot id: E0TDW7
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

314260:PB2503 RS00915
gene id: 314260:PB2503_RS00915
uniprot id: E0TBI4
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

314260:PB2503 RS05915
gene id: 314260:PB2503_RS05915
uniprot id: E0THQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

314260:PB2503 RS04370
gene id: 314260:PB2503_RS04370
uniprot id: E0TFC6
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS05785
gene id: 314260:PB2503_RS05785
uniprot id: E0THM8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS05230
gene id: 314260:PB2503_RS05230
uniprot id: E0TGX4
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

314260:PB2503 RS01445
gene id: 314260:PB2503_RS01445
uniprot id: E0TBW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

314260:PB2503 RS03710
gene id: 314260:PB2503_RS03710
uniprot id: E0TEM8
names: Similarity
messages: Belongs to the CutA family.

314260:PB2503 RS04980
gene id: 314260:PB2503_RS04980
uniprot id: E0TGC4
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS12630
gene id: 314260:PB2503_RS12630
uniprot id: E0TGR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

314260:PB2503 RS10930
gene id: 314260:PB2503_RS10930
uniprot id: E0TCW0
names: Similarity
messages: Belongs to the GST superfamily.

314260:PB2503 RS04850
gene id: 314260:PB2503_RS04850
uniprot id: E0TG98
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

314260:PB2503 RS09610
gene id: 314260:PB2503_RS09610
uniprot id: E0TFG2
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

314260:PB2503 RS05215
gene id: 314260:PB2503_RS05215
uniprot id: E0TGX1
names: Similarity
messages: Belongs to the GSP E family.

314260:PB2503 RS04265
gene id: 314260:PB2503_RS04265
uniprot id: E0TFA4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

314260:PB2503 RS03990
gene id: 314260:PB2503_RS03990
uniprot id: E0TF48
names: Similarity
messages: Belongs to the histone deacetylase family.

314260:PB2503 RS09355
gene id: 314260:PB2503_RS09355
uniprot id: E0TEE7
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

314260:PB2503 RS13225
gene id: 314260:PB2503_RS13225
uniprot id: E0THY9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

314260:PB2503 RS11070
gene id: 314260:PB2503_RS11070
uniprot id: E0TCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS00635
gene id: 314260:PB2503_RS00635
uniprot id: E0TBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

314260:PB2503 RS03715
gene id: 314260:PB2503_RS03715
uniprot id: E0TEM9
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

314260:PB2503 RS01690
gene id: 314260:PB2503_RS01690
uniprot id: E0TC76
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02375
gene id: 314260:PB2503_RS02375
uniprot id: E0TCQ6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

314260:PB2503 RS02965
gene id: 314260:PB2503_RS02965
uniprot id: E0TDK5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS13595
gene id: 314260:PB2503_RS13595
uniprot id: E0TB34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

314260:PB2503 RS02105
gene id: 314260:PB2503_RS02105
uniprot id: E0TCK2
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

314260:PB2503 RS09385
gene id: 314260:PB2503_RS09385
uniprot id: E0TEF3
names: Similarity
messages: Belongs to the HesB/IscA family.

314260:PB2503 RS03835
gene id: 314260:PB2503_RS03835
uniprot id: E0TEQ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

314260:PB2503 RS02815
gene id: 314260:PB2503_RS02815
uniprot id: E0TDH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

314260:PB2503 RS07090
gene id: 314260:PB2503_RS07090
uniprot id: E0TGG2
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS11815
gene id: 314260:PB2503_RS11815
uniprot id: E0TF33
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.
messages: Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0).

314260:PB2503 RS05875
gene id: 314260:PB2503_RS05875
uniprot id: E0THP6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS11235
gene id: 314260:PB2503_RS11235
uniprot id: E0TDV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS02165
gene id: 314260:PB2503_RS02165
uniprot id: E0TCL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

314260:PB2503 RS12890
gene id: 314260:PB2503_RS12890
uniprot id: E0THD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

314260:PB2503 RS00375
gene id: 314260:PB2503_RS00375
uniprot id: E0TB46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

314260:PB2503 RS05795
gene id: 314260:PB2503_RS05795
uniprot id: E0THN0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

314260:PB2503 RS07370
gene id: 314260:PB2503_RS07370
uniprot id: E0TH49
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

314260:PB2503 RS12855
gene id: 314260:PB2503_RS12855
uniprot id: E0TGV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

314260:PB2503 RS10030
gene id: 314260:PB2503_RS10030
uniprot id: E0TGN7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS06050
gene id: 314260:PB2503_RS06050
uniprot id: E0TI36
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

314260:PB2503 RS12730
gene id: 314260:PB2503_RS12730
uniprot id: E0TGT4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

314260:PB2503 RS08980
gene id: 314260:PB2503_RS08980
uniprot id: E0TDD4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

314260:PB2503 RS08330
gene id: 314260:PB2503_RS08330
uniprot id: E0TC32
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

314260:PB2503 RS10995
gene id: 314260:PB2503_RS10995
uniprot id: E0TCX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS12520
gene id: 314260:PB2503_RS12520
uniprot id: E0TG79
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

314260:PB2503 RS07145
gene id: 314260:PB2503_RS07145
uniprot id: E0TGH3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

314260:PB2503 RS09115
gene id: 314260:PB2503_RS09115
uniprot id: E0TDR9
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

314260:PB2503 RS10565
gene id: 314260:PB2503_RS10565
uniprot id: E0TIF5
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

314260:PB2503 RS11410
gene id: 314260:PB2503_RS11410
uniprot id: E0TEG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

314260:PB2503 RS06680
gene id: 314260:PB2503_RS06680
uniprot id: E0TEC7
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

314260:PB2503 RS08430
gene id: 314260:PB2503_RS08430
uniprot id: E0TCF7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS13990
gene id: 314260:PB2503_RS13990
uniprot id: E0TBQ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GSP I family.
messages: Cell inner membrane
messages: Cleaved by prepilin peptidase.
messages: Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane
messages: Type II secretion is composed of four main components: the outer membrane complex, the inner membrane complex, the cytoplasmic secretion ATPase and the periplasm-spanning pseudopilus.

314260:PB2503 RS06810
gene id: 314260:PB2503_RS06810
uniprot id: E0TEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

314260:PB2503 RS07050
gene id: 314260:PB2503_RS07050
uniprot id: E0TFX4
names: Function
messages: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY.

314260:PB2503 RS04520
gene id: 314260:PB2503_RS04520
uniprot id: E0TFQ9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

314260:PB2503 RS10060
gene id: 314260:PB2503_RS10060
uniprot id: E0TGP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

314260:PB2503 RS08975
gene id: 314260:PB2503_RS08975
uniprot id: E0TDD3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

314260:PB2503 RS01130
gene id: 314260:PB2503_RS01130
uniprot id: E0TBM4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

314260:PB2503 RS10015
gene id: 314260:PB2503_RS10015
uniprot id: E0TGN4
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

314260:PB2503 RS10400
gene id: 314260:PB2503_RS10400
uniprot id: E0THU8
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS06730
gene id: 314260:PB2503_RS06730
uniprot id: E0TEU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS09150
gene id: 314260:PB2503_RS09150
uniprot id: E0TDS6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS10515
gene id: 314260:PB2503_RS10515
uniprot id: E0TIE5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS01870
gene id: 314260:PB2503_RS01870
uniprot id: E0TCB1
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

314260:PB2503 RS04990
gene id: 314260:PB2503_RS04990
uniprot id: E0TGC6
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

314260:PB2503 RS06700
gene id: 314260:PB2503_RS06700
uniprot id: E0TET3
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08935
gene id: 314260:PB2503_RS08935
uniprot id: E0TDC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

314260:PB2503 RS09620
gene id: 314260:PB2503_RS09620
uniprot id: E0TFG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS09010
gene id: 314260:PB2503_RS09010
uniprot id: E0TDE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

314260:PB2503 RS09045
gene id: 314260:PB2503_RS09045
uniprot id: E0TDQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

314260:PB2503 RS12790
gene id: 314260:PB2503_RS12790
uniprot id: E0TGU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS11405
gene id: 314260:PB2503_RS11405
uniprot id: E0TEG4
names: Subcellular Location Annotation
messages: Cytoplasm

314260:PB2503 RS05820
gene id: 314260:PB2503_RS05820
uniprot id: E0THN5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS11905
gene id: 314260:PB2503_RS11905
uniprot id: E0TFH8
names: Similarity
messages: Belongs to the ParB family.

314260:PB2503 RS03445
gene id: 314260:PB2503_RS03445
uniprot id: E0TE37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

314260:PB2503 RS00260
gene id: 314260:PB2503_RS00260
uniprot id: E0TB23
names: Similarity
messages: Belongs to the DEAD box helicase family.

314260:PB2503 RS10600
gene id: 314260:PB2503_RS10600
uniprot id: E0TIG3
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

314260:PB2503 RS06250
gene id: 314260:PB2503_RS06250
uniprot id: E0TI77
names: Function
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.

314260:PB2503 RS02510
gene id: 314260:PB2503_RS02510
uniprot id: E0TD13
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

314260:PB2503 RS01520
gene id: 314260:PB2503_RS01520
uniprot id: E0TBY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

314260:PB2503 RS04835
gene id: 314260:PB2503_RS04835
uniprot id: E0TG95
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

314260:PB2503 RS01885
gene id: 314260:PB2503_RS01885
uniprot id: E0TCB4
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

314260:PB2503 RS03285
gene id: 314260:PB2503_RS03285
uniprot id: E0TE05
names: Similarity
messages: Belongs to the UPF0434 family.

314260:PB2503 RS00365
gene id: 314260:PB2503_RS00365
uniprot id: E0TB44
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS12525
gene id: 314260:PB2503_RS12525
uniprot id: E0TG80
names: Subcellular Location Annotation
messages: Cell outer membrane

314260:PB2503 RS07465
gene id: 314260:PB2503_RS07465
uniprot id: E0TH67
names: Similarity
messages: Belongs to the type III secretion exporter family.

314260:PB2503 RS03110
gene id: 314260:PB2503_RS03110
uniprot id: E0TDN4
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

314260:PB2503 RS00950
gene id: 314260:PB2503_RS00950
uniprot id: E0TBI9
names: Function
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

314260:PB2503 RS10685
gene id: 314260:PB2503_RS10685
uniprot id: E0TC41
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS07450
gene id: 314260:PB2503_RS07450
uniprot id: E0TH64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

314260:PB2503 RS02785
gene id: 314260:PB2503_RS02785
uniprot id: E0TD66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS08190
gene id: 314260:PB2503_RS08190
uniprot id: E0TC03
names: Subcellular Location Annotation
messages: Mitochondrion

314260:PB2503 RS06535
gene id: 314260:PB2503_RS06535
uniprot id: E0TE99
names: Similarity
messages: Belongs to the citrate synthase family.

314260:PB2503 RS07885
gene id: 314260:PB2503_RS07885
uniprot id: E0TBD9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

314260:PB2503 RS01095
gene id: 314260:PB2503_RS01095
uniprot id: E0TBL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

314260:PB2503 RS05745
gene id: 314260:PB2503_RS05745
uniprot id: E0THM1
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

314260:PB2503 RS09705
gene id: 314260:PB2503_RS09705
uniprot id: E0TFY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS08130
gene id: 314260:PB2503_RS08130
uniprot id: E0TBR3
names: Similarity
messages: Belongs to the LOG family.

314260:PB2503 RS03780
gene id: 314260:PB2503_RS03780
uniprot id: E0TEP2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

314260:PB2503 RS05030
gene id: 314260:PB2503_RS05030
uniprot id: E0TGD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

314260:PB2503 RS00590
gene id: 314260:PB2503_RS00590
uniprot id: E0TB94
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS13110
gene id: 314260:PB2503_RS13110
uniprot id: E0THI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS04015
gene id: 314260:PB2503_RS04015
uniprot id: E0TF53
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS14135
gene id: 314260:PB2503_RS14135
uniprot id: E0TEI4
names: Caution
names: Similarity
messages: Belongs to the NTE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS03900
gene id: 314260:PB2503_RS03900
uniprot id: E0TER5
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

314260:PB2503 RS09515
gene id: 314260:PB2503_RS09515
uniprot id: E0TEX2
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

314260:PB2503 RS08995
gene id: 314260:PB2503_RS08995
uniprot id: E0TDD7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

314260:PB2503 RS03505
gene id: 314260:PB2503_RS03505
uniprot id: E0TE49
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

314260:PB2503 RS07860
gene id: 314260:PB2503_RS07860
uniprot id: E0TBD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

314260:PB2503 RS09000
gene id: 314260:PB2503_RS09000
uniprot id: E0TDD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

314260:PB2503 RS01655
gene id: 314260:PB2503_RS01655
uniprot id: E0TC69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

314260:PB2503 RS04665
gene id: 314260:PB2503_RS04665
uniprot id: E0TFT8
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

314260:PB2503 RS00995
gene id: 314260:PB2503_RS00995
uniprot id: E0TBJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

314260:PB2503 RS09780
gene id: 314260:PB2503_RS09780
uniprot id: E0TG03
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

314260:PB2503 RS07745
gene id: 314260:PB2503_RS07745
uniprot id: E0TIC3
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

314260:PB2503 RS02420
gene id: 314260:PB2503_RS02420
uniprot id: E0TCZ5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS08905
gene id: 314260:PB2503_RS08905
uniprot id: E0TDB9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

314260:PB2503 RS07965
gene id: 314260:PB2503_RS07965
uniprot id: E0TBF4
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS03790
gene id: 314260:PB2503_RS03790
uniprot id: E0TEP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

314260:PB2503 RS02195
gene id: 314260:PB2503_RS02195
uniprot id: E0TCM0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

314260:PB2503 RS10070
gene id: 314260:PB2503_RS10070
uniprot id: E0TH87
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

314260:PB2503 RS01375
gene id: 314260:PB2503_RS01375
uniprot id: E0TBV4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS07845
gene id: 314260:PB2503_RS07845
uniprot id: E0TB53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

314260:PB2503 RS14720
gene id: 314260:PB2503_RS14720
uniprot id: E0TH98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

314260:PB2503 RS12720
gene id: 314260:PB2503_RS12720
uniprot id: E0TGT2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS00330
gene id: 314260:PB2503_RS00330
uniprot id: E0TB37
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

314260:PB2503 RS03500
gene id: 314260:PB2503_RS03500
uniprot id: E0TE48
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-52 and Arg-55) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

314260:PB2503 RS08105
gene id: 314260:PB2503_RS08105
uniprot id: E0TBQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP L family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS00690
gene id: 314260:PB2503_RS00690
uniprot id: E0TBB2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

314260:PB2503 RS03395
gene id: 314260:PB2503_RS03395
uniprot id: E0TE27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

314260:PB2503 RS12775
gene id: 314260:PB2503_RS12775
uniprot id: E0TGU3
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

314260:PB2503 RS03330
gene id: 314260:PB2503_RS03330
uniprot id: E0TE14
names: Subcellular Location Annotation
messages: Nucleus

314260:PB2503 RS09340
gene id: 314260:PB2503_RS09340
uniprot id: E0TEE4
names: Function
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

314260:PB2503 RS13960
gene id: 314260:PB2503_RS13960
uniprot id: E0TH58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

314260:PB2503 RS02020
gene id: 314260:PB2503_RS02020
uniprot id: E0TCI5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS04130
gene id: 314260:PB2503_RS04130
uniprot id: E0TF76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

314260:PB2503 RS09015
gene id: 314260:PB2503_RS09015
uniprot id: E0TDE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

314260:PB2503 RS05470
gene id: 314260:PB2503_RS05470
uniprot id: E0TH20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

314260:PB2503 RS10675
gene id: 314260:PB2503_RS10675
uniprot id: E0TC39
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

314260:PB2503 RS03620
gene id: 314260:PB2503_RS03620
uniprot id: E0TEL0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

314260:PB2503 RS02450
gene id: 314260:PB2503_RS02450
uniprot id: E0TD02
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

314260:PB2503 RS04345
gene id: 314260:PB2503_RS04345
uniprot id: E0TFC1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.

314260:PB2503 RS08195
gene id: 314260:PB2503_RS08195
uniprot id: E0TC04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

314260:PB2503 RS10145
gene id: 314260:PB2503_RS10145
uniprot id: E0THA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

314260:PB2503 RS09345
gene id: 314260:PB2503_RS09345
uniprot id: E0TEE5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

314260:PB2503 RS10300
gene id: 314260:PB2503_RS10300
uniprot id: E0THT0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

314260:PB2503 RS02610
gene id: 314260:PB2503_RS02610
uniprot id: E0TD33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS07185
gene id: 314260:PB2503_RS07185
uniprot id: E0TGI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

314260:PB2503 RS04400
gene id: 314260:PB2503_RS04400
uniprot id: E0TFN5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS09730
gene id: 314260:PB2503_RS09730
uniprot id: E0TFZ2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

314260:PB2503 RS08005
gene id: 314260:PB2503_RS08005
uniprot id: E0TBN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

314260:PB2503 RS09020
gene id: 314260:PB2503_RS09020
uniprot id: E0TDE2
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

314260:PB2503 RS05920
gene id: 314260:PB2503_RS05920
uniprot id: E0THQ5
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

314260:PB2503 RS09065
gene id: 314260:PB2503_RS09065
uniprot id: E0TDQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS10575
gene id: 314260:PB2503_RS10575
uniprot id: E0TIF7
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS02935
gene id: 314260:PB2503_RS02935
uniprot id: E0TDJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

314260:PB2503 RS12335
gene id: 314260:PB2503_RS12335
uniprot id: E0TG40
names: Similarity
messages: Belongs to the GARS family.

314260:PB2503 RS05050
gene id: 314260:PB2503_RS05050
uniprot id: E0TGD7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

314260:PB2503 RS05815
gene id: 314260:PB2503_RS05815
uniprot id: E0THN4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

314260:PB2503 RS03410
gene id: 314260:PB2503_RS03410
uniprot id: E0TE30
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS09070
gene id: 314260:PB2503_RS09070
uniprot id: E0TDR0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

314260:PB2503 RS10615
gene id: 314260:PB2503_RS10615
uniprot id: E0TIG6
names: Similarity
messages: Belongs to the OmpW/AlkL family.

314260:PB2503 RS12970
gene id: 314260:PB2503_RS12970
uniprot id: E0THF1
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

314260:PB2503 RS12385
gene id: 314260:PB2503_RS12385
uniprot id: E0TG51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PpiC/parvulin rotamase family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS04530
gene id: 314260:PB2503_RS04530
uniprot id: E0TFR2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS12460
gene id: 314260:PB2503_RS12460
uniprot id: E0TG67
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

314260:PB2503 RS12165
gene id: 314260:PB2503_RS12165
uniprot id: E0TFL8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS09185
gene id: 314260:PB2503_RS09185
uniprot id: E0TDT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

314260:PB2503 RS02335
gene id: 314260:PB2503_RS02335
uniprot id: E0TCP8
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

314260:PB2503 RS06725
gene id: 314260:PB2503_RS06725
uniprot id: E0TET9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.

314260:PB2503 RS01755
gene id: 314260:PB2503_RS01755
uniprot id: E0TC89
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

314260:PB2503 RS01365
gene id: 314260:PB2503_RS01365
uniprot id: E0TBV2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

314260:PB2503 RS13240
gene id: 314260:PB2503_RS13240
uniprot id: E0THZ2
names: Similarity
messages: Belongs to the FrmR/RcnR family.

314260:PB2503 RS02930
gene id: 314260:PB2503_RS02930
uniprot id: E0TDJ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

314260:PB2503 RS04675
gene id: 314260:PB2503_RS04675
uniprot id: E0TFU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

314260:PB2503 RS13050
gene id: 314260:PB2503_RS13050
uniprot id: E0THG7
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

314260:PB2503 RS03660
gene id: 314260:PB2503_RS03660
uniprot id: E0TEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

314260:PB2503 RS01350
gene id: 314260:PB2503_RS01350
uniprot id: E0TBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

314260:PB2503 RS03690
gene id: 314260:PB2503_RS03690
uniprot id: E0TEM4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

314260:PB2503 RS01305
gene id: 314260:PB2503_RS01305
uniprot id: E0TBU0
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

314260:PB2503 RS07775
gene id: 314260:PB2503_RS07775
uniprot id: E0TIC9
names: Similarity
messages: Belongs to the GST superfamily.

314260:PB2503 RS08275
gene id: 314260:PB2503_RS08275
uniprot id: E0TC21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

314260:PB2503 RS10940
gene id: 314260:PB2503_RS10940
uniprot id: E0TCW2
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

314260:PB2503 RS11030
gene id: 314260:PB2503_RS11030
uniprot id: E0TCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

314260:PB2503 RS01005
gene id: 314260:PB2503_RS01005
uniprot id: E0TBJ9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

314260:PB2503 RS08660
gene id: 314260:PB2503_RS08660
uniprot id: E0TD71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS03915
gene id: 314260:PB2503_RS03915
uniprot id: E0TER8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

314260:PB2503 RS12905
gene id: 314260:PB2503_RS12905
uniprot id: E0THD7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS12875
gene id: 314260:PB2503_RS12875
uniprot id: E0THD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

314260:PB2503 RS05250
gene id: 314260:PB2503_RS05250
uniprot id: E0TGX8
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

314260:PB2503 RS00520
gene id: 314260:PB2503_RS00520
uniprot id: E0TB81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

314260:PB2503 RS01225
gene id: 314260:PB2503_RS01225
uniprot id: E0TBS5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

314260:PB2503 RS04755
gene id: 314260:PB2503_RS04755
uniprot id: E0TFV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS03775
gene id: 314260:PB2503_RS03775
uniprot id: E0TEP1
names: Similarity
messages: Belongs to the PhoH family.

314260:PB2503 RS00860
gene id: 314260:PB2503_RS00860
uniprot id: E0TBH3
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

314260:PB2503 RS09080
gene id: 314260:PB2503_RS09080
uniprot id: E0TDR2
names: Similarity
messages: Belongs to the SfsA family.

314260:PB2503 RS08165
gene id: 314260:PB2503_RS08165
uniprot id: E0TBZ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

314260:PB2503 RS01440
gene id: 314260:PB2503_RS01440
uniprot id: E0TBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

314260:PB2503 RS11140
gene id: 314260:PB2503_RS11140
uniprot id: E0TDF8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

314260:PB2503 RS12235
gene id: 314260:PB2503_RS12235
uniprot id: E0TG21
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08890
gene id: 314260:PB2503_RS08890
uniprot id: E0TDB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

314260:PB2503 RS03820
gene id: 314260:PB2503_RS03820
uniprot id: E0TEQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

314260:PB2503 RS07460
gene id: 314260:PB2503_RS07460
uniprot id: E0TH66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

314260:PB2503 RS07820
gene id: 314260:PB2503_RS07820
uniprot id: E0TID9
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

314260:PB2503 RS09135
gene id: 314260:PB2503_RS09135
uniprot id: E0TDS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

314260:PB2503 RS07210
gene id: 314260:PB2503_RS07210
uniprot id: E0TGI5
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS11810
gene id: 314260:PB2503_RS11810
uniprot id: E0TF32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0060 family.
messages: Cell inner membrane

314260:PB2503 RS13865
gene id: 314260:PB2503_RS13865
uniprot id: E0TGZ6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

314260:PB2503 RS09865
gene id: 314260:PB2503_RS09865
uniprot id: E0TG19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

314260:PB2503 RS05325
gene id: 314260:PB2503_RS05325
uniprot id: E0TGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

314260:PB2503 RS02385
gene id: 314260:PB2503_RS02385
uniprot id: E0TCQ8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

314260:PB2503 RS07165
gene id: 314260:PB2503_RS07165
uniprot id: E0TGH7
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

314260:PB2503 RS13300
gene id: 314260:PB2503_RS13300
uniprot id: E0TI02
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

314260:PB2503 RS05580
gene id: 314260:PB2503_RS05580
uniprot id: E0THI8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS13000
gene id: 314260:PB2503_RS13000
uniprot id: E0THF7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS07880
gene id: 314260:PB2503_RS07880
uniprot id: E0TBD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer.

314260:PB2503 RS03420
gene id: 314260:PB2503_RS03420
uniprot id: E0TE32
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

314260:PB2503 RS02740
gene id: 314260:PB2503_RS02740
uniprot id: E0TD57
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS10810
gene id: 314260:PB2503_RS10810
uniprot id: E0TCG7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

314260:PB2503 RS06520
gene id: 314260:PB2503_RS06520
uniprot id: E0TE96
names: Subcellular Location Annotation
messages: Cytoplasm

314260:PB2503 RS09820
gene id: 314260:PB2503_RS09820
uniprot id: E0TG10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurD2 subfamily.
messages: Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.
messages: Cytoplasm

314260:PB2503 RS07335
gene id: 314260:PB2503_RS07335
uniprot id: E0TH43
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

314260:PB2503 RS05240
gene id: 314260:PB2503_RS05240
uniprot id: E0TGX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

314260:PB2503 RS04440
gene id: 314260:PB2503_RS04440
uniprot id: E0TFP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

314260:PB2503 RS00825
gene id: 314260:PB2503_RS00825
uniprot id: E0TBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

314260:PB2503 RS11260
gene id: 314260:PB2503_RS11260
uniprot id: E0TDV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS03360
gene id: 314260:PB2503_RS03360
uniprot id: E0TE20
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

314260:PB2503 RS12315
gene id: 314260:PB2503_RS12315
uniprot id: E0TG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

314260:PB2503 RS04540
gene id: 314260:PB2503_RS04540
uniprot id: E0TFR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

314260:PB2503 RS13635
gene id: 314260:PB2503_RS13635
uniprot id: E0TBH6
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

314260:PB2503 RS02220
gene id: 314260:PB2503_RS02220
uniprot id: E0TCM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

314260:PB2503 RS10980
gene id: 314260:PB2503_RS10980
uniprot id: E0TCX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

314260:PB2503 RS02190
gene id: 314260:PB2503_RS02190
uniprot id: E0TCL9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvC family.
messages: Binds 2 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer which binds Holliday junction (HJ) DNA. The HJ becomes 2-fold symmetrical on binding to RuvC with unstacked arms; it has a different conformation from HJ DNA in complex with RuvA. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

314260:PB2503 RS02275
gene id: 314260:PB2503_RS02275
uniprot id: E0TCN6
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

314260:PB2503 RS10110
gene id: 314260:PB2503_RS10110
uniprot id: E0TH94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

314260:PB2503 RS04020
gene id: 314260:PB2503_RS04020
uniprot id: E0TF54
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Cell inner membrane
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

314260:PB2503 RS03685
gene id: 314260:PB2503_RS03685
uniprot id: E0TEM3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

314260:PB2503 RS11250
gene id: 314260:PB2503_RS11250
uniprot id: E0TDV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

314260:PB2503 RS01695
gene id: 314260:PB2503_RS01695
uniprot id: E0TC77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Cell membrane

314260:PB2503 RS10885
gene id: 314260:PB2503_RS10885
uniprot id: E0TCH8
names: Function
messages: Acts on leucine, isoleucine and valine.

314260:PB2503 RS09175
gene id: 314260:PB2503_RS09175
uniprot id: E0TDT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS04135
gene id: 314260:PB2503_RS04135
uniprot id: E0TF77
names: Similarity
messages: Belongs to the TrpF family.

314260:PB2503 RS08140
gene id: 314260:PB2503_RS08140
uniprot id: E0TBR5
names: Similarity
messages: Belongs to the UPF0047 family.

314260:PB2503 RS03005
gene id: 314260:PB2503_RS03005
uniprot id: E0TDL3
names: Similarity
messages: Belongs to the DEAD box helicase family.

314260:PB2503 RS03430
gene id: 314260:PB2503_RS03430
uniprot id: E0TE34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

314260:PB2503 RS08825
gene id: 314260:PB2503_RS08825
uniprot id: E0TDA2
names: Function
messages: Multidrug efflux pump.

314260:PB2503 RS13475
gene id: 314260:PB2503_RS13475
uniprot id: E0TIJ2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS11470
gene id: 314260:PB2503_RS11470
uniprot id: E0TD69
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

314260:PB2503 RS05065
gene id: 314260:PB2503_RS05065
uniprot id: E0TGE0
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS12475
gene id: 314260:PB2503_RS12475
uniprot id: E0TG70
names: Similarity
messages: Belongs to the peptidase S49 family.

314260:PB2503 RS05700
gene id: 314260:PB2503_RS05700
uniprot id: E0THL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

314260:PB2503 RS14715
gene id: 314260:PB2503_RS14715
uniprot id: E0TG11
names: Function
names: Similarity
messages: Belongs to the MurL family.
messages: Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.

314260:PB2503 RS11455
gene id: 314260:PB2503_RS11455
uniprot id: E0TEH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

314260:PB2503 RS04210
gene id: 314260:PB2503_RS04210
uniprot id: E0TF93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

314260:PB2503 RS01465
gene id: 314260:PB2503_RS01465
uniprot id: E0TBX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS01515
gene id: 314260:PB2503_RS01515
uniprot id: E0TBY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

314260:PB2503 RS11275
gene id: 314260:PB2503_RS11275
uniprot id: E0TDW2
names: Similarity
messages: Belongs to the FGGY kinase family.

314260:PB2503 RS04790
gene id: 314260:PB2503_RS04790
uniprot id: E0TG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

314260:PB2503 RS10290
gene id: 314260:PB2503_RS10290
uniprot id: E0THS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

314260:PB2503 RS12540
gene id: 314260:PB2503_RS12540
uniprot id: E0TGP5
names: Similarity
messages: Belongs to the asparagine synthetase family.

314260:PB2503 RS10455
gene id: 314260:PB2503_RS10455
uniprot id: E0THV9
names: Similarity
messages: Belongs to the lycopene cyclase family.

314260:PB2503 RS04330
gene id: 314260:PB2503_RS04330
uniprot id: E0TFB7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.

314260:PB2503 RS05530
gene id: 314260:PB2503_RS05530
uniprot id: E0TH34
names: Similarity
messages: Belongs to the argonaute family. Long pAgo subfamily.

314260:PB2503 RS12405
gene id: 314260:PB2503_RS12405
uniprot id: E0TG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

314260:PB2503 RS12010
gene id: 314260:PB2503_RS12010
uniprot id: E0TFJ7
names: Similarity
messages: Belongs to the TrbE/VirB4 family.

314260:PB2503 RS07395
gene id: 314260:PB2503_RS07395
uniprot id: E0TH54
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

314260:PB2503 RS04550
gene id: 314260:PB2503_RS04550
uniprot id: E0TFR6
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

314260:PB2503 RS01545
gene id: 314260:PB2503_RS01545
uniprot id: E0TBY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS10835
gene id: 314260:PB2503_RS10835
uniprot id: E0TCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

314260:PB2503 RS09320
gene id: 314260:PB2503_RS09320
uniprot id: E0TEE0
names: Similarity
messages: Belongs to the PhoH family.

314260:PB2503 RS00830
gene id: 314260:PB2503_RS00830
uniprot id: E0TBG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

314260:PB2503 RS02490
gene id: 314260:PB2503_RS02490
uniprot id: E0TD09
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

314260:PB2503 RS10915
gene id: 314260:PB2503_RS10915
uniprot id: E0TCV7
names: Similarity
messages: Belongs to the glutamate synthase family.

314260:PB2503 RS10495
gene id: 314260:PB2503_RS10495
uniprot id: E0TIE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.
messages: Binds 1 Co(2+) ion per subunit.
messages: Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.

314260:PB2503 RS04910
gene id: 314260:PB2503_RS04910
uniprot id: E0TGB0
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08480
gene id: 314260:PB2503_RS08480
uniprot id: E0TCR9
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

314260:PB2503 RS12950
gene id: 314260:PB2503_RS12950
uniprot id: E0THE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabB family.
messages: Cell inner membrane
messages: Forms a complex with DabA.
messages: Membrane
messages: Part of an energy-coupled inorganic carbon pump.

314260:PB2503 RS04940
gene id: 314260:PB2503_RS04940
uniprot id: E0TGB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS03800
gene id: 314260:PB2503_RS03800
uniprot id: E0TEP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Cytoplasm
messages: Homotetramer.

314260:PB2503 RS12215
gene id: 314260:PB2503_RS12215
uniprot id: E0TFM8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

314260:PB2503 RS11465
gene id: 314260:PB2503_RS11465
uniprot id: E0TEH6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

314260:PB2503 RS04710
gene id: 314260:PB2503_RS04710
uniprot id: E0TFU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

314260:PB2503 RS08290
gene id: 314260:PB2503_RS08290
uniprot id: E0TC24
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

314260:PB2503 RS04055
gene id: 314260:PB2503_RS04055
uniprot id: E0TF61
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

314260:PB2503 RS05670
gene id: 314260:PB2503_RS05670
uniprot id: E0THK5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS00270
gene id: 314260:PB2503_RS00270
uniprot id: E0TB25
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

314260:PB2503 RS08225
gene id: 314260:PB2503_RS08225
uniprot id: E0TC11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

314260:PB2503 RS09435
gene id: 314260:PB2503_RS09435
uniprot id: E0TEG3
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

314260:PB2503 RS07075
gene id: 314260:PB2503_RS07075
uniprot id: E0TFX9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

314260:PB2503 RS04875
gene id: 314260:PB2503_RS04875
uniprot id: E0TGA3
names: Similarity
messages: Belongs to the peptidase A24 family.

314260:PB2503 RS08340
gene id: 314260:PB2503_RS08340
uniprot id: E0TCD7
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

314260:PB2503 RS06690
gene id: 314260:PB2503_RS06690
uniprot id: E0TEC9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

314260:PB2503 RS08765
gene id: 314260:PB2503_RS08765
uniprot id: E0TD91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

314260:PB2503 RS12205
gene id: 314260:PB2503_RS12205
uniprot id: E0TFM6
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

314260:PB2503 RS10160
gene id: 314260:PB2503_RS10160
uniprot id: E0THA4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

314260:PB2503 RS08965
gene id: 314260:PB2503_RS08965
uniprot id: E0TDD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

314260:PB2503 RS12265
gene id: 314260:PB2503_RS12265
uniprot id: E0TG26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

314260:PB2503 RS12900
gene id: 314260:PB2503_RS12900
uniprot id: E0THD6
names: Similarity
messages: Belongs to the OmpW/AlkL family.

314260:PB2503 RS11255
gene id: 314260:PB2503_RS11255
uniprot id: E0TDV7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS01990
gene id: 314260:PB2503_RS01990
uniprot id: E0TCD5
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS01880
gene id: 314260:PB2503_RS01880
uniprot id: E0TCB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

314260:PB2503 RS10790
gene id: 314260:PB2503_RS10790
uniprot id: E0TCG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the etk/wzc family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS08235
gene id: 314260:PB2503_RS08235
uniprot id: E0TC13
names: Similarity
messages: Belongs to the TlyA family.

314260:PB2503 RS01580
gene id: 314260:PB2503_RS01580
uniprot id: E0TBZ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

314260:PB2503 RS08145
gene id: 314260:PB2503_RS08145
uniprot id: E0TBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

314260:PB2503 RS08270
gene id: 314260:PB2503_RS08270
uniprot id: E0TC20
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.

314260:PB2503 RS08100
gene id: 314260:PB2503_RS08100
uniprot id: E0TBQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP K family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS01795
gene id: 314260:PB2503_RS01795
uniprot id: E0TC97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

314260:PB2503 RS09510
gene id: 314260:PB2503_RS09510
uniprot id: E0TEX1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
messages: Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3).

314260:PB2503 RS09755
gene id: 314260:PB2503_RS09755
uniprot id: E0TFZ8
names: Similarity
messages: Belongs to the ClpA/ClpB family.

314260:PB2503 RS09025
gene id: 314260:PB2503_RS09025
uniprot id: E0TDE3
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

314260:PB2503 RS08070
gene id: 314260:PB2503_RS08070
uniprot id: E0TBQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.
messages: Belongs to the GSP E family.
messages: Cell inner membrane

314260:PB2503 RS02270
gene id: 314260:PB2503_RS02270
uniprot id: E0TCN5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

314260:PB2503 RS02255
gene id: 314260:PB2503_RS02255
uniprot id: E0TCN2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS00335
gene id: 314260:PB2503_RS00335
uniprot id: E0TB38
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

314260:PB2503 RS02620
gene id: 314260:PB2503_RS02620
uniprot id: E0TD35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

314260:PB2503 RS03270
gene id: 314260:PB2503_RS03270
uniprot id: E0TE02
names: Similarity
messages: Belongs to the PRORSD1 family.

314260:PB2503 RS08160
gene id: 314260:PB2503_RS08160
uniprot id: E0TBR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

314260:PB2503 RS08315
gene id: 314260:PB2503_RS08315
uniprot id: E0TC29
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

314260:PB2503 RS06450
gene id: 314260:PB2503_RS06450
uniprot id: E0TE81
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

314260:PB2503 RS08465
gene id: 314260:PB2503_RS08465
uniprot id: E0TCR5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

314260:PB2503 RS08620
gene id: 314260:PB2503_RS08620
uniprot id: E0TCU7
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

314260:PB2503 RS02315
gene id: 314260:PB2503_RS02315
uniprot id: E0TCP4
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS12945
gene id: 314260:PB2503_RS12945
uniprot id: E0THE6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS11855
gene id: 314260:PB2503_RS11855
uniprot id: E0TF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

314260:PB2503 RS08180
gene id: 314260:PB2503_RS08180
uniprot id: E0TC01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

314260:PB2503 RS09880
gene id: 314260:PB2503_RS09880
uniprot id: E0TGK9
names: Similarity
messages: Belongs to the SAICAR synthetase family.

314260:PB2503 RS00890
gene id: 314260:PB2503_RS00890
uniprot id: E0TBH9
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

314260:PB2503 RS06195
gene id: 314260:PB2503_RS06195
uniprot id: E0TI66
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

314260:PB2503 RS07640
gene id: 314260:PB2503_RS07640
uniprot id: E0TIA2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

314260:PB2503 RS03300
gene id: 314260:PB2503_RS03300
uniprot id: E0TE08
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

314260:PB2503 RS13185
gene id: 314260:PB2503_RS13185
uniprot id: E0THX9
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

314260:PB2503 RS03875
gene id: 314260:PB2503_RS03875
uniprot id: E0TER0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

314260:PB2503 RS00470
gene id: 314260:PB2503_RS00470
uniprot id: E0TB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Could be part of an ABC transporter complex.
messages: Membrane

314260:PB2503 RS01115
gene id: 314260:PB2503_RS01115
uniprot id: E0TBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

314260:PB2503 RS10450
gene id: 314260:PB2503_RS10450
uniprot id: E0THV8
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

314260:PB2503 RS00320
gene id: 314260:PB2503_RS00320
uniprot id: E0TB35
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

314260:PB2503 RS05975
gene id: 314260:PB2503_RS05975
uniprot id: E0TI21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

314260:PB2503 RS01000
gene id: 314260:PB2503_RS01000
uniprot id: E0TBJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

314260:PB2503 RS09215
gene id: 314260:PB2503_RS09215
uniprot id: E0TDT9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

314260:PB2503 RS07215
gene id: 314260:PB2503_RS07215
uniprot id: E0TGI6
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS00340
gene id: 314260:PB2503_RS00340
uniprot id: E0TB39
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

314260:PB2503 RS07970
gene id: 314260:PB2503_RS07970
uniprot id: E0TBF5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

314260:PB2503 RS12610
gene id: 314260:PB2503_RS12610
uniprot id: E0TGQ9
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

314260:PB2503 RS01535
gene id: 314260:PB2503_RS01535
uniprot id: E0TBY6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

314260:PB2503 RS08770
gene id: 314260:PB2503_RS08770
uniprot id: E0TD92
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

314260:PB2503 RS01530
gene id: 314260:PB2503_RS01530
uniprot id: E0TBY5
names: Similarity
messages: Belongs to the UPF0262 family.

314260:PB2503 RS10895
gene id: 314260:PB2503_RS10895
uniprot id: E0TCI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS08355
gene id: 314260:PB2503_RS08355
uniprot id: E0TCE0
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

314260:PB2503 RS02800
gene id: 314260:PB2503_RS02800
uniprot id: E0TD69
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

314260:PB2503 RS04645
gene id: 314260:PB2503_RS04645
uniprot id: E0TFT4
names: Similarity
messages: Belongs to the YggT family.

314260:PB2503 RS11335
gene id: 314260:PB2503_RS11335
uniprot id: E0TDX4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

314260:PB2503 RS09875
gene id: 314260:PB2503_RS09875
uniprot id: E0TGK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

314260:PB2503 RS01630
gene id: 314260:PB2503_RS01630
uniprot id: E0TC64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

314260:PB2503 RS07315
gene id: 314260:PB2503_RS07315
uniprot id: E0TGK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

314260:PB2503 RS13370
gene id: 314260:PB2503_RS13370
uniprot id: E0TI17
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS08920
gene id: 314260:PB2503_RS08920
uniprot id: E0TDC2
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

314260:PB2503 RS01915
gene id: 314260:PB2503_RS01915
uniprot id: E0TCC0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

314260:PB2503 RS03595
gene id: 314260:PB2503_RS03595
uniprot id: E0TEK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS02395
gene id: 314260:PB2503_RS02395
uniprot id: E0TCR0
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

314260:PB2503 RS13345
gene id: 314260:PB2503_RS13345
uniprot id: E0TI12
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS07850
gene id: 314260:PB2503_RS07850
uniprot id: E0TB54
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

314260:PB2503 RS03605
gene id: 314260:PB2503_RS03605
uniprot id: E0TEK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

314260:PB2503 RS06415
gene id: 314260:PB2503_RS06415
uniprot id: E0TE74
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

314260:PB2503 RS06460
gene id: 314260:PB2503_RS06460
uniprot id: E0TE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

314260:PB2503 RS11995
gene id: 314260:PB2503_RS11995
uniprot id: E0TFJ4
names: Similarity
messages: Belongs to the GSP E family.

314260:PB2503 RS12030
gene id: 314260:PB2503_RS12030
uniprot id: E0TFK1
names: Similarity
messages: Belongs to the TrbG/VirB9 family.

314260:PB2503 RS03890
gene id: 314260:PB2503_RS03890
uniprot id: E0TER3
names: Similarity
messages: Belongs to the SDHAF4 family.

314260:PB2503 RS08955
gene id: 314260:PB2503_RS08955
uniprot id: E0TDC9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

314260:PB2503 RS13075
gene id: 314260:PB2503_RS13075
uniprot id: E0THH3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

314260:PB2503 RS07030
gene id: 314260:PB2503_RS07030
uniprot id: E0TFX2
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

314260:PB2503 RS09055
gene id: 314260:PB2503_RS09055
uniprot id: E0TDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

314260:PB2503 RS12895
gene id: 314260:PB2503_RS12895
uniprot id: E0THD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS01850
gene id: 314260:PB2503_RS01850
uniprot id: E0TCA7
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

314260:PB2503 RS01845
gene id: 314260:PB2503_RS01845
uniprot id: E0TCA6
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

314260:PB2503 RS10355
gene id: 314260:PB2503_RS10355
uniprot id: E0THU0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

314260:PB2503 RS08635
gene id: 314260:PB2503_RS08635
uniprot id: E0TCV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

314260:PB2503 RS03475
gene id: 314260:PB2503_RS03475
uniprot id: E0TE43
names: Similarity
messages: Belongs to the peptidase S66 family.

314260:PB2503 RS04900
gene id: 314260:PB2503_RS04900
uniprot id: E0TGA8
names: Similarity
messages: Belongs to the GSP E family.

314260:PB2503 RS08230
gene id: 314260:PB2503_RS08230
uniprot id: E0TC12
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

314260:PB2503 RS01740
gene id: 314260:PB2503_RS01740
uniprot id: E0TC86
names: Similarity
messages: Belongs to the GST superfamily.

314260:PB2503 RS12870
gene id: 314260:PB2503_RS12870
uniprot id: E0TGW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

314260:PB2503 RS07345
gene id: 314260:PB2503_RS07345
uniprot id: E0TH45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

314260:PB2503 RS10245
gene id: 314260:PB2503_RS10245
uniprot id: E0THC1
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

314260:PB2503 RS03930
gene id: 314260:PB2503_RS03930
uniprot id: E0TES1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

314260:PB2503 RS08695
gene id: 314260:PB2503_RS08695
uniprot id: E0TD77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

314260:PB2503 RS08670
gene id: 314260:PB2503_RS08670
uniprot id: E0TD72
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

314260:PB2503 RS08925
gene id: 314260:PB2503_RS08925
uniprot id: E0TDC3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

314260:PB2503 RS05890
gene id: 314260:PB2503_RS05890
uniprot id: E0THP9
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS11205
gene id: 314260:PB2503_RS11205
uniprot id: E0TDH0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS03310
gene id: 314260:PB2503_RS03310
uniprot id: E0TE10
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

314260:PB2503 RS03385
gene id: 314260:PB2503_RS03385
uniprot id: E0TE25
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

314260:PB2503 RS08110
gene id: 314260:PB2503_RS08110
uniprot id: E0TBQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP M family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS04650
gene id: 314260:PB2503_RS04650
uniprot id: E0TFT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

314260:PB2503 RS13265
gene id: 314260:PB2503_RS13265
uniprot id: E0THZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

314260:PB2503 RS13485
gene id: 314260:PB2503_RS13485
uniprot id: E0TIJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

314260:PB2503 RS12635
gene id: 314260:PB2503_RS12635
uniprot id: E0TGR5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

314260:PB2503 RS11315
gene id: 314260:PB2503_RS11315
uniprot id: E0TDX0
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

314260:PB2503 RS10965
gene id: 314260:PB2503_RS10965
uniprot id: E0TCW7
names: Function
names: Similarity
messages: Belongs to the polysaccharide deacetylase family.
messages: Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.

314260:PB2503 RS01860
gene id: 314260:PB2503_RS01860
uniprot id: E0TCA9
names: Similarity
messages: Belongs to the thioredoxin family. DsbE subfamily.

314260:PB2503 RS07455
gene id: 314260:PB2503_RS07455
uniprot id: E0TH65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

314260:PB2503 RS04205
gene id: 314260:PB2503_RS04205
uniprot id: E0TF92
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

314260:PB2503 RS02995
gene id: 314260:PB2503_RS02995
uniprot id: E0TDL1
names: Similarity
messages: Belongs to the YciI family.

314260:PB2503 RS08845
gene id: 314260:PB2503_RS08845
uniprot id: E0TDA7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

314260:PB2503 RS00990
gene id: 314260:PB2503_RS00990
uniprot id: E0TBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

314260:PB2503 RS01495
gene id: 314260:PB2503_RS01495
uniprot id: E0TBX8
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the APS kinase family.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Catalyzes the synthesis of activated sulfate.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Proposed to provide activated sulfate for transfer to Nod factor. ATP sulfurylase may be the GTPase, regulating ATP sulfurylase activity.
messages: Sulfate-activating enzymes, NodP and NodQ, may be physically associated.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

314260:PB2503 RS01415
gene id: 314260:PB2503_RS01415
uniprot id: E0TBW2
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

314260:PB2503 RS08650
gene id: 314260:PB2503_RS08650
uniprot id: E0TCV3
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS02565
gene id: 314260:PB2503_RS02565
uniprot id: E0TD24
names: Similarity
messages: Belongs to the thioredoxin family.

314260:PB2503 RS11055
gene id: 314260:PB2503_RS11055
uniprot id: E0TCY5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

314260:PB2503 RS04285
gene id: 314260:PB2503_RS04285
uniprot id: E0TFA8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

314260:PB2503 RS02245
gene id: 314260:PB2503_RS02245
uniprot id: E0TCN0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

314260:PB2503 RS10025
gene id: 314260:PB2503_RS10025
uniprot id: E0TGN6
names: Similarity
messages: Belongs to the Nudix hydrolase family.

314260:PB2503 RS13380
gene id: 314260:PB2503_RS13380
uniprot id: E0TI19
names: Similarity
messages: Belongs to the MbcT/ParT/Res family.

314260:PB2503 RS10540
gene id: 314260:PB2503_RS10540
uniprot id: E0TIF0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

314260:PB2503 RS07660
gene id: 314260:PB2503_RS07660
uniprot id: E0TIA6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

314260:PB2503 RS05925
gene id: 314260:PB2503_RS05925
uniprot id: E0THQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

314260:PB2503 RS09155
gene id: 314260:PB2503_RS09155
uniprot id: E0TDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

314260:PB2503 RS01775
gene id: 314260:PB2503_RS01775
uniprot id: E0TC93
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

314260:PB2503 RS07730
gene id: 314260:PB2503_RS07730
uniprot id: E0TIC0
names: Similarity
messages: Belongs to the UPF0174 family.

314260:PB2503 RS09675
gene id: 314260:PB2503_RS09675
uniprot id: E0TFY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

314260:PB2503 RS08945
gene id: 314260:PB2503_RS08945
uniprot id: E0TDC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

314260:PB2503 RS00515
gene id: 314260:PB2503_RS00515
uniprot id: E0TB80
names: Similarity
messages: Belongs to the MreC family.

314260:PB2503 RS04760
gene id: 314260:PB2503_RS04760
uniprot id: E0TFV8
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

314260:PB2503 RS01925
gene id: 314260:PB2503_RS01925
uniprot id: E0TCC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
messages: Oligomer of 12 subunits arranged in the form of two hexameric ring.

314260:PB2503 RS12020
gene id: 314260:PB2503_RS12020
uniprot id: E0TFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

314260:PB2503 RS10420
gene id: 314260:PB2503_RS10420
uniprot id: E0THV2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS02400
gene id: 314260:PB2503_RS02400
uniprot id: E0TCZ1
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

314260:PB2503 RS01960
gene id: 314260:PB2503_RS01960
uniprot id: E0TCD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

314260:PB2503 RS02015
gene id: 314260:PB2503_RS02015
uniprot id: E0TCI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

314260:PB2503 RS04050
gene id: 314260:PB2503_RS04050
uniprot id: E0TF60
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

314260:PB2503 RS01040
gene id: 314260:PB2503_RS01040
uniprot id: E0TBK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

314260:PB2503 RS08075
gene id: 314260:PB2503_RS08075
uniprot id: E0TBQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Component of the type II secretion system inner membrane complex required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.
messages: Membrane

314260:PB2503 RS04535
gene id: 314260:PB2503_RS04535
uniprot id: E0TFR3
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

314260:PB2503 RS09790
gene id: 314260:PB2503_RS09790
uniprot id: E0TG05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

314260:PB2503 RS01950
gene id: 314260:PB2503_RS01950
uniprot id: E0TCC8
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

314260:PB2503 RS12415
gene id: 314260:PB2503_RS12415
uniprot id: E0TG57
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

314260:PB2503 RS10045
gene id: 314260:PB2503_RS10045
uniprot id: E0TGP0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS08410
gene id: 314260:PB2503_RS08410
uniprot id: E0TCF2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS07530
gene id: 314260:PB2503_RS07530
uniprot id: E0TH81
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

314260:PB2503 RS10520
gene id: 314260:PB2503_RS10520
uniprot id: E0TIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
messages: Cell inner membrane

314260:PB2503 RS09225
gene id: 314260:PB2503_RS09225
uniprot id: E0TDU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThiG family.
messages: Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
messages: Cytoplasm
messages: Homotetramer. Forms heterodimers with either ThiH or ThiS.

314260:PB2503 RS03825
gene id: 314260:PB2503_RS03825
uniprot id: E0TEQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

314260:PB2503 RS12395
gene id: 314260:PB2503_RS12395
uniprot id: E0TG53
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

314260:PB2503 RS04230
gene id: 314260:PB2503_RS04230
uniprot id: E0TF97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

314260:PB2503 RS11095
gene id: 314260:PB2503_RS11095
uniprot id: E0TDE9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

314260:PB2503 RS06080
gene id: 314260:PB2503_RS06080
uniprot id: E0TI42
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS01750
gene id: 314260:PB2503_RS01750
uniprot id: E0TC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS05045
gene id: 314260:PB2503_RS05045
uniprot id: E0TGD6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

314260:PB2503 RS09465
gene id: 314260:PB2503_RS09465
uniprot id: E0TEW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

314260:PB2503 RS10525
gene id: 314260:PB2503_RS10525
uniprot id: E0TIE7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS06170
gene id: 314260:PB2503_RS06170
uniprot id: E0TI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

314260:PB2503 RS05690
gene id: 314260:PB2503_RS05690
uniprot id: E0THL0
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08435
gene id: 314260:PB2503_RS08435
uniprot id: E0TCF8
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS04845
gene id: 314260:PB2503_RS04845
uniprot id: E0TG97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

314260:PB2503 RS13480
gene id: 314260:PB2503_RS13480
uniprot id: E0TIJ3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

314260:PB2503 RS03375
gene id: 314260:PB2503_RS03375
uniprot id: E0TE23
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

314260:PB2503 RS02205
gene id: 314260:PB2503_RS02205
uniprot id: E0TCM2
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

314260:PB2503 RS10555
gene id: 314260:PB2503_RS10555
uniprot id: E0TIF3
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

314260:PB2503 RS01315
gene id: 314260:PB2503_RS01315
uniprot id: E0TBU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

314260:PB2503 RS03145
gene id: 314260:PB2503_RS03145
uniprot id: E0TDP1
names: Similarity
messages: Belongs to the GSP E family.

314260:PB2503 RS13450
gene id: 314260:PB2503_RS13450
uniprot id: E0TII7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

314260:PB2503 RS04420
gene id: 314260:PB2503_RS04420
uniprot id: E0TFN9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

314260:PB2503 RS08875
gene id: 314260:PB2503_RS08875
uniprot id: E0TDB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

314260:PB2503 RS00300
gene id: 314260:PB2503_RS00300
uniprot id: E0TB31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

314260:PB2503 RS02590
gene id: 314260:PB2503_RS02590
uniprot id: E0TD29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

314260:PB2503 RS09600
gene id: 314260:PB2503_RS09600
uniprot id: E0TFG0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

314260:PB2503 RS08600
gene id: 314260:PB2503_RS08600
uniprot id: E0TCU3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

314260:PB2503 RS03295
gene id: 314260:PB2503_RS03295
uniprot id: E0TE07
names: Similarity
messages: Belongs to the thioester dehydratase family. FabA subfamily.

314260:PB2503 RS04105
gene id: 314260:PB2503_RS04105
uniprot id: E0TF71
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

314260:PB2503 RS13500
gene id: 314260:PB2503_RS13500
uniprot id: E0TIJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

314260:PB2503 RS06590
gene id: 314260:PB2503_RS06590
uniprot id: E0TEA9
names: Similarity
messages: Belongs to the peptidase C56 family.

314260:PB2503 RS10635
gene id: 314260:PB2503_RS10635
uniprot id: E0TIH0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

314260:PB2503 RS08970
gene id: 314260:PB2503_RS08970
uniprot id: E0TDD2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

314260:PB2503 RS05255
gene id: 314260:PB2503_RS05255
uniprot id: E0TGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

314260:PB2503 RS10530
gene id: 314260:PB2503_RS10530
uniprot id: E0TIE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS12960
gene id: 314260:PB2503_RS12960
uniprot id: E0THE9
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

314260:PB2503 RS07795
gene id: 314260:PB2503_RS07795
uniprot id: E0TID4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

314260:PB2503 RS11790
gene id: 314260:PB2503_RS11790
uniprot id: E0TF28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

314260:PB2503 RS04725
gene id: 314260:PB2503_RS04725
uniprot id: E0TFV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

314260:PB2503 RS07925
gene id: 314260:PB2503_RS07925
uniprot id: E0TBE7
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

314260:PB2503 RS01235
gene id: 314260:PB2503_RS01235
uniprot id: E0TBS7
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

314260:PB2503 RS13180
gene id: 314260:PB2503_RS13180
uniprot id: E0THX8
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

314260:PB2503 RS08575
gene id: 314260:PB2503_RS08575
uniprot id: E0TCT8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Arsenite methyltransferase family.

314260:PB2503 RS00410
gene id: 314260:PB2503_RS00410
uniprot id: E0TB58
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

314260:PB2503 RS06315
gene id: 314260:PB2503_RS06315
uniprot id: E0TI90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

314260:PB2503 RS06090
gene id: 314260:PB2503_RS06090
uniprot id: E0TI44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

314260:PB2503 RS02820
gene id: 314260:PB2503_RS02820
uniprot id: E0TDH6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

314260:PB2503 RS09260
gene id: 314260:PB2503_RS09260
uniprot id: E0TDU8
names: Caution
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS09470
gene id: 314260:PB2503_RS09470
uniprot id: E0TEW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

314260:PB2503 RS03340
gene id: 314260:PB2503_RS03340
uniprot id: E0TE16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

314260:PB2503 RS11325
gene id: 314260:PB2503_RS11325
uniprot id: E0TDX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

314260:PB2503 RS13100
gene id: 314260:PB2503_RS13100
uniprot id: E0THH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS07705
gene id: 314260:PB2503_RS07705
uniprot id: E0TIB5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

314260:PB2503 RS00430
gene id: 314260:PB2503_RS00430
uniprot id: E0TB62
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS12925
gene id: 314260:PB2503_RS12925
uniprot id: E0THE1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS09715
gene id: 314260:PB2503_RS09715
uniprot id: E0TFY8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

314260:PB2503 RS02880
gene id: 314260:PB2503_RS02880
uniprot id: E0TDI8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

314260:PB2503 RS02260
gene id: 314260:PB2503_RS02260
uniprot id: E0TCN3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

314260:PB2503 RS11190
gene id: 314260:PB2503_RS11190
uniprot id: E0TDG7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

314260:PB2503 RS02750
gene id: 314260:PB2503_RS02750
uniprot id: E0TD59
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02640
gene id: 314260:PB2503_RS02640
uniprot id: E0TD39
names: Similarity
messages: Belongs to the PrpD family.

314260:PB2503 RS12420
gene id: 314260:PB2503_RS12420
uniprot id: E0TG58
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS01770
gene id: 314260:PB2503_RS01770
uniprot id: E0TC92
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

314260:PB2503 RS02030
gene id: 314260:PB2503_RS02030
uniprot id: E0TCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

314260:PB2503 RS02680
gene id: 314260:PB2503_RS02680
uniprot id: E0TD46
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS03920
gene id: 314260:PB2503_RS03920
uniprot id: E0TER9
names: Function
names: Similarity
messages: Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
messages: Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.

314260:PB2503 RS10395
gene id: 314260:PB2503_RS10395
uniprot id: E0THU7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

314260:PB2503 RS08505
gene id: 314260:PB2503_RS08505
uniprot id: E0TCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

314260:PB2503 RS10955
gene id: 314260:PB2503_RS10955
uniprot id: E0TCW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

314260:PB2503 RS02210
gene id: 314260:PB2503_RS02210
uniprot id: E0TCM3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

314260:PB2503 RS08950
gene id: 314260:PB2503_RS08950
uniprot id: E0TDC8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

314260:PB2503 RS13955
gene id: 314260:PB2503_RS13955
uniprot id: E0TH51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FlgA family.
messages: Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
messages: Periplasm

314260:PB2503 RS12115
gene id: 314260:PB2503_RS12115
uniprot id: E0TFK9
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02445
gene id: 314260:PB2503_RS02445
uniprot id: E0TD01
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

314260:PB2503 RS06670
gene id: 314260:PB2503_RS06670
uniprot id: E0TEC5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

314260:PB2503 RS09665
gene id: 314260:PB2503_RS09665
uniprot id: E0TFH3
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.

314260:PB2503 RS09630
gene id: 314260:PB2503_RS09630
uniprot id: E0TFG7
names: Subcellular Location Annotation
messages: Cytoplasm

314260:PB2503 RS07865
gene id: 314260:PB2503_RS07865
uniprot id: E0TBD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

314260:PB2503 RS08885
gene id: 314260:PB2503_RS08885
uniprot id: E0TDB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

314260:PB2503 RS06655
gene id: 314260:PB2503_RS06655
uniprot id: E0TEC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS02390
gene id: 314260:PB2503_RS02390
uniprot id: E0TCQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

314260:PB2503 RS02690
gene id: 314260:PB2503_RS02690
uniprot id: E0TD48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX11/CtaG family.
messages: Cell inner membrane
messages: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.

314260:PB2503 RS07440
gene id: 314260:PB2503_RS07440
uniprot id: E0TH62
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

314260:PB2503 RS03980
gene id: 314260:PB2503_RS03980
uniprot id: E0TET1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

314260:PB2503 RS06870
gene id: 314260:PB2503_RS06870
uniprot id: E0TFD9
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS02895
gene id: 314260:PB2503_RS02895
uniprot id: E0TDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

314260:PB2503 RS02200
gene id: 314260:PB2503_RS02200
uniprot id: E0TCM1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

314260:PB2503 RS10140
gene id: 314260:PB2503_RS10140
uniprot id: E0THA0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 7 family.

314260:PB2503 RS03720
gene id: 314260:PB2503_RS03720
uniprot id: E0TEN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

314260:PB2503 RS11530
gene id: 314260:PB2503_RS11530
uniprot id: E0TEI9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

314260:PB2503 RS01135
gene id: 314260:PB2503_RS01135
uniprot id: E0TBM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

314260:PB2503 RS07365
gene id: 314260:PB2503_RS07365
uniprot id: E0TH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

314260:PB2503 RS06595
gene id: 314260:PB2503_RS06595
uniprot id: E0TEB0
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

314260:PB2503 RS09485
gene id: 314260:PB2503_RS09485
uniprot id: E0TEW6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

314260:PB2503 RS04995
gene id: 314260:PB2503_RS04995
uniprot id: E0TGC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

314260:PB2503 RS01890
gene id: 314260:PB2503_RS01890
uniprot id: E0TCB5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

314260:PB2503 RS12220
gene id: 314260:PB2503_RS12220
uniprot id: E0TFM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm

314260:PB2503 RS01035
gene id: 314260:PB2503_RS01035
uniprot id: E0TBK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

314260:PB2503 RS08910
gene id: 314260:PB2503_RS08910
uniprot id: E0TDC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

314260:PB2503 RS08535
gene id: 314260:PB2503_RS08535
uniprot id: E0TCS9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

314260:PB2503 RS07385
gene id: 314260:PB2503_RS07385
uniprot id: E0TH52
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

314260:PB2503 RS05190
gene id: 314260:PB2503_RS05190
uniprot id: E0TGW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

314260:PB2503 RS07710
gene id: 314260:PB2503_RS07710
uniprot id: E0TIB6
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

314260:PB2503 RS08095
gene id: 314260:PB2503_RS08095
uniprot id: E0TBQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP J family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS07475
gene id: 314260:PB2503_RS07475
uniprot id: E0TH69
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

314260:PB2503 RS12810
gene id: 314260:PB2503_RS12810
uniprot id: E0TGV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell inner membrane
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS01360
gene id: 314260:PB2503_RS01360
uniprot id: E0TBV1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

314260:PB2503 RS03765
gene id: 314260:PB2503_RS03765
uniprot id: E0TEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

314260:PB2503 RS11110
gene id: 314260:PB2503_RS11110
uniprot id: E0TDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS02875
gene id: 314260:PB2503_RS02875
uniprot id: E0TDI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

314260:PB2503 RS00705
gene id: 314260:PB2503_RS00705
uniprot id: E0TBB5
names: Similarity
messages: Belongs to the UPF0145 family.

314260:PB2503 RS00630
gene id: 314260:PB2503_RS00630
uniprot id: E0TBA2
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02685
gene id: 314260:PB2503_RS02685
uniprot id: E0TD47
names: Similarity
messages: Belongs to the SufE family.

314260:PB2503 RS07300
gene id: 314260:PB2503_RS07300
uniprot id: E0TGK1
names: Similarity
messages: Belongs to the MotB family.

314260:PB2503 RS04110
gene id: 314260:PB2503_RS04110
uniprot id: E0TF72
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

314260:PB2503 RS13360
gene id: 314260:PB2503_RS13360
uniprot id: E0TI15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

314260:PB2503 RS12955
gene id: 314260:PB2503_RS12955
uniprot id: E0THE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

314260:PB2503 RS01675
gene id: 314260:PB2503_RS01675
uniprot id: E0TC73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

314260:PB2503 RS12830
gene id: 314260:PB2503_RS12830
uniprot id: E0TGV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS02500
gene id: 314260:PB2503_RS02500
uniprot id: E0TD11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

314260:PB2503 RS06245
gene id: 314260:PB2503_RS06245
uniprot id: E0TI76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

314260:PB2503 RS02115
gene id: 314260:PB2503_RS02115
uniprot id: E0TCK4
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the reversible phosphorylation of pyruvate and phosphate.

314260:PB2503 RS10125
gene id: 314260:PB2503_RS10125
uniprot id: E0TH97
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

314260:PB2503 RS03415
gene id: 314260:PB2503_RS03415
uniprot id: E0TE31
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

314260:PB2503 RS05715
gene id: 314260:PB2503_RS05715
uniprot id: E0THL5
names: Similarity
messages: Belongs to the TPP enzyme family.

314260:PB2503 RS12255
gene id: 314260:PB2503_RS12255
uniprot id: E0TG24
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

314260:PB2503 RS08210
gene id: 314260:PB2503_RS08210
uniprot id: E0TC07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

314260:PB2503 RS00975
gene id: 314260:PB2503_RS00975
uniprot id: E0TBJ3
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS09245
gene id: 314260:PB2503_RS09245
uniprot id: E0TDU5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

314260:PB2503 RS06720
gene id: 314260:PB2503_RS06720
uniprot id: E0TET8
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

314260:PB2503 RS09375
gene id: 314260:PB2503_RS09375
uniprot id: E0TEF1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
messages: Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.

314260:PB2503 RS09695
gene id: 314260:PB2503_RS09695
uniprot id: E0TFY4
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS11480
gene id: 314260:PB2503_RS11480
uniprot id: E0TEH9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS09415
gene id: 314260:PB2503_RS09415
uniprot id: E0TEF9
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

314260:PB2503 RS11740
gene id: 314260:PB2503_RS11740
uniprot id: E0TF18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

314260:PB2503 RS05805
gene id: 314260:PB2503_RS05805
uniprot id: E0THN2
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

314260:PB2503 RS13540
gene id: 314260:PB2503_RS13540
uniprot id: E0TIK5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS02100
gene id: 314260:PB2503_RS02100
uniprot id: E0TCK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

314260:PB2503 RS12535
gene id: 314260:PB2503_RS12535
uniprot id: E0TGP4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

314260:PB2503 RS12940
gene id: 314260:PB2503_RS12940
uniprot id: E0THE5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS12515
gene id: 314260:PB2503_RS12515
uniprot id: E0TG78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

314260:PB2503 RS10370
gene id: 314260:PB2503_RS10370
uniprot id: E0THU2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS09740
gene id: 314260:PB2503_RS09740
uniprot id: E0TFZ4
names: Similarity
messages: Belongs to the peptidase S11 family.

314260:PB2503 RS04350
gene id: 314260:PB2503_RS04350
uniprot id: E0TFC2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

314260:PB2503 RS12330
gene id: 314260:PB2503_RS12330
uniprot id: E0TG39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

314260:PB2503 RS06285
gene id: 314260:PB2503_RS06285
uniprot id: E0TI84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

314260:PB2503 RS12230
gene id: 314260:PB2503_RS12230
uniprot id: E0TG20
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

314260:PB2503 RS06145
gene id: 314260:PB2503_RS06145
uniprot id: E0TI55
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueG family.
messages: Binds 2 [4Fe-4S] clusters per monomer.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS03745
gene id: 314260:PB2503_RS03745
uniprot id: E0TEN5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

314260:PB2503 RS03045
gene id: 314260:PB2503_RS03045
uniprot id: E0TDM0
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

314260:PB2503 RS04215
gene id: 314260:PB2503_RS04215
uniprot id: E0TF94
names: Similarity
messages: Belongs to the peptidase M16 family.

314260:PB2503 RS13200
gene id: 314260:PB2503_RS13200
uniprot id: E0THY4
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

314260:PB2503 RS02535
gene id: 314260:PB2503_RS02535
uniprot id: E0TD18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

314260:PB2503 RS03560
gene id: 314260:PB2503_RS03560
uniprot id: E0TE60
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

314260:PB2503 RS08185
gene id: 314260:PB2503_RS08185
uniprot id: E0TC02
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

314260:PB2503 RS07680
gene id: 314260:PB2503_RS07680
uniprot id: E0TIB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS09785
gene id: 314260:PB2503_RS09785
uniprot id: E0TG04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

314260:PB2503 RS02345
gene id: 314260:PB2503_RS02345
uniprot id: E0TCQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

314260:PB2503 RS06675
gene id: 314260:PB2503_RS06675
uniprot id: E0TEC6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

314260:PB2503 RS04115
gene id: 314260:PB2503_RS04115
uniprot id: E0TF73
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

314260:PB2503 RS07855
gene id: 314260:PB2503_RS07855
uniprot id: E0TBD3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS00195
gene id: 314260:PB2503_RS00195
uniprot id: E0TB12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

314260:PB2503 RS05010
gene id: 314260:PB2503_RS05010
uniprot id: E0TGC9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

314260:PB2503 RS13255
gene id: 314260:PB2503_RS13255
uniprot id: E0THZ5
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS12320
gene id: 314260:PB2503_RS12320
uniprot id: E0TG37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

314260:PB2503 RS04120
gene id: 314260:PB2503_RS04120
uniprot id: E0TF74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

314260:PB2503 RS07310
gene id: 314260:PB2503_RS07310
uniprot id: E0TGK3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

314260:PB2503 RS12245
gene id: 314260:PB2503_RS12245
uniprot id: E0TG22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS08915
gene id: 314260:PB2503_RS08915
uniprot id: E0TDC1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

314260:PB2503 RS02120
gene id: 314260:PB2503_RS02120
uniprot id: E0TCK5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

314260:PB2503 RS12620
gene id: 314260:PB2503_RS12620
uniprot id: E0TGR1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

314260:PB2503 RS05970
gene id: 314260:PB2503_RS05970
uniprot id: E0TI20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

314260:PB2503 RS01975
gene id: 314260:PB2503_RS01975
uniprot id: E0TCD2
names: Similarity
messages: Belongs to the Skp family.

314260:PB2503 RS01280
gene id: 314260:PB2503_RS01280
uniprot id: E0TBT5
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 zinc ion per subunit.

314260:PB2503 RS15060
gene id: 314260:PB2503_RS15060
uniprot id: E0THC5
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

314260:PB2503 RS02080
gene id: 314260:PB2503_RS02080
uniprot id: E0TCJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

314260:PB2503 RS10235
gene id: 314260:PB2503_RS10235
uniprot id: E0THB9
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

314260:PB2503 RS02455
gene id: 314260:PB2503_RS02455
uniprot id: E0TD03
names: Similarity
messages: Belongs to the YkuD family.

314260:PB2503 RS00645
gene id: 314260:PB2503_RS00645
uniprot id: E0TBA5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

314260:PB2503 RS06760
gene id: 314260:PB2503_RS06760
uniprot id: E0TEU6
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

314260:PB2503 RS10780
gene id: 314260:PB2503_RS10780
uniprot id: E0TCG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

314260:PB2503 RS02755
gene id: 314260:PB2503_RS02755
uniprot id: E0TD60
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08930
gene id: 314260:PB2503_RS08930
uniprot id: E0TDC4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

314260:PB2503 RS03925
gene id: 314260:PB2503_RS03925
uniprot id: E0TES0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS05860
gene id: 314260:PB2503_RS05860
uniprot id: E0THP3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

314260:PB2503 RS07750
gene id: 314260:PB2503_RS07750
uniprot id: E0TIC4
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS07990
gene id: 314260:PB2503_RS07990
uniprot id: E0TBF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS04145
gene id: 314260:PB2503_RS04145
uniprot id: E0TF79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

314260:PB2503 RS06495
gene id: 314260:PB2503_RS06495
uniprot id: E0TE91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS02855
gene id: 314260:PB2503_RS02855
uniprot id: E0TDI3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

314260:PB2503 RS07305
gene id: 314260:PB2503_RS07305
uniprot id: E0TGK2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

314260:PB2503 RS13025
gene id: 314260:PB2503_RS13025
uniprot id: E0THG2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

314260:PB2503 RS03240
gene id: 314260:PB2503_RS03240
uniprot id: E0TDZ7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS07840
gene id: 314260:PB2503_RS07840
uniprot id: E0TB52
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

314260:PB2503 RS05000
gene id: 314260:PB2503_RS05000
uniprot id: E0TGC8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

314260:PB2503 RS04970
gene id: 314260:PB2503_RS04970
uniprot id: E0TGC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

314260:PB2503 RS04485
gene id: 314260:PB2503_RS04485
uniprot id: E0TFQ2
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

314260:PB2503 RS00740
gene id: 314260:PB2503_RS00740
uniprot id: E0TBC3
names: Similarity
messages: Belongs to the GST superfamily.

314260:PB2503 RS01900
gene id: 314260:PB2503_RS01900
uniprot id: E0TCB7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

314260:PB2503 RS07675
gene id: 314260:PB2503_RS07675
uniprot id: E0TIA9
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

314260:PB2503 RS00785
gene id: 314260:PB2503_RS00785
uniprot id: E0TBD2
names: Similarity
messages: Belongs to the CdaR family.

314260:PB2503 RS08445
gene id: 314260:PB2503_RS08445
uniprot id: E0TCR1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

314260:PB2503 RS11365
gene id: 314260:PB2503_RS11365
uniprot id: E0TDX9
names: Cofactor
names: Similarity
messages: Belongs to the alkaline phosphatase family.
messages: Binds 1 Mg(2+) ion.
messages: Binds 2 Zn(2+) ions.

314260:PB2503 RS03570
gene id: 314260:PB2503_RS03570
uniprot id: E0TE62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

314260:PB2503 RS02475
gene id: 314260:PB2503_RS02475
uniprot id: E0TD06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

314260:PB2503 RS11320
gene id: 314260:PB2503_RS11320
uniprot id: E0TDX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS01145
gene id: 314260:PB2503_RS01145
uniprot id: E0TBM7
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS08400
gene id: 314260:PB2503_RS08400
uniprot id: E0TCF0
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

314260:PB2503 RS09195
gene id: 314260:PB2503_RS09195
uniprot id: E0TDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein.

314260:PB2503 RS04045
gene id: 314260:PB2503_RS04045
uniprot id: E0TF59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

314260:PB2503 RS08990
gene id: 314260:PB2503_RS08990
uniprot id: E0TDD6
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

314260:PB2503 RS05755
gene id: 314260:PB2503_RS05755
uniprot id: E0THM3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS01345
gene id: 314260:PB2503_RS01345
uniprot id: E0TBU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS09930
gene id: 314260:PB2503_RS09930
uniprot id: E0TGL9
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

314260:PB2503 RS02655
gene id: 314260:PB2503_RS02655
uniprot id: E0TD42
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

314260:PB2503 RS12530
gene id: 314260:PB2503_RS12530
uniprot id: E0TG81
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS02890
gene id: 314260:PB2503_RS02890
uniprot id: E0TDJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

314260:PB2503 RS05735
gene id: 314260:PB2503_RS05735
uniprot id: E0THL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

314260:PB2503 RS09305
gene id: 314260:PB2503_RS09305
uniprot id: E0TED8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

314260:PB2503 RS02720
gene id: 314260:PB2503_RS02720
uniprot id: E0TD53
names: Similarity
messages: Belongs to the peptidase U62 family.

314260:PB2503 RS03550
gene id: 314260:PB2503_RS03550
uniprot id: E0TE58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

314260:PB2503 RS11830
gene id: 314260:PB2503_RS11830
uniprot id: E0TF36
names: Subcellular Location Annotation
messages: Cell membrane

314260:PB2503 RS07870
gene id: 314260:PB2503_RS07870
uniprot id: E0TBD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

314260:PB2503 RS00620
gene id: 314260:PB2503_RS00620
uniprot id: E0TBA0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

314260:PB2503 RS04090
gene id: 314260:PB2503_RS04090
uniprot id: E0TF68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

314260:PB2503 RS08030
gene id: 314260:PB2503_RS08030
uniprot id: E0TBP3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

314260:PB2503 RS11080
gene id: 314260:PB2503_RS11080
uniprot id: E0TCY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

314260:PB2503 RS03885
gene id: 314260:PB2503_RS03885
uniprot id: E0TER2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS08755
gene id: 314260:PB2503_RS08755
uniprot id: E0TD89
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
messages: Monomer.

314260:PB2503 RS09455
gene id: 314260:PB2503_RS09455
uniprot id: E0TEW0
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

314260:PB2503 RS03105
gene id: 314260:PB2503_RS03105
uniprot id: E0TDN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbI/VirB10 family.
messages: Membrane

314260:PB2503 RS11535
gene id: 314260:PB2503_RS11535
uniprot id: E0TEJ1
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS07035
gene id: 314260:PB2503_RS07035
uniprot id: E0TFX3
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

314260:PB2503 RS04765
gene id: 314260:PB2503_RS04765
uniprot id: E0TFV9
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

314260:PB2503 RS13045
gene id: 314260:PB2503_RS13045
uniprot id: E0THG6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

314260:PB2503 RS07470
gene id: 314260:PB2503_RS07470
uniprot id: E0TH68
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

314260:PB2503 RS03910
gene id: 314260:PB2503_RS03910
uniprot id: E0TER7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS12560
gene id: 314260:PB2503_RS12560
uniprot id: E0TGP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Membrane

314260:PB2503 RS10330
gene id: 314260:PB2503_RS10330
uniprot id: E0THT6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS07250
gene id: 314260:PB2503_RS07250
uniprot id: E0TGJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

314260:PB2503 RS08940
gene id: 314260:PB2503_RS08940
uniprot id: E0TDC6
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

314260:PB2503 RS03705
gene id: 314260:PB2503_RS03705
uniprot id: E0TEM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

314260:PB2503 RS03630
gene id: 314260:PB2503_RS03630
uniprot id: E0TEL2
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

314260:PB2503 RS00735
gene id: 314260:PB2503_RS00735
uniprot id: E0TBC2
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

314260:PB2503 RS00325
gene id: 314260:PB2503_RS00325
uniprot id: E0TB36
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

314260:PB2503 RS08570
gene id: 314260:PB2503_RS08570
uniprot id: E0TCT7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

314260:PB2503 RS12175
gene id: 314260:PB2503_RS12175
uniprot id: E0TFM0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

314260:PB2503 RS07060
gene id: 314260:PB2503_RS07060
uniprot id: E0TFX6
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

314260:PB2503 RS02065
gene id: 314260:PB2503_RS02065
uniprot id: E0TCJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS02765
gene id: 314260:PB2503_RS02765
uniprot id: E0TD62
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

314260:PB2503 RS03965
gene id: 314260:PB2503_RS03965
uniprot id: E0TES8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

314260:PB2503 RS05600
gene id: 314260:PB2503_RS05600
uniprot id: E0THJ2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

314260:PB2503 RS07330
gene id: 314260:PB2503_RS07330
uniprot id: E0TH42
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

314260:PB2503 RS05790
gene id: 314260:PB2503_RS05790
uniprot id: E0THM9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

314260:PB2503 RS05070
gene id: 314260:PB2503_RS05070
uniprot id: E0TGE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

314260:PB2503 RS03120
gene id: 314260:PB2503_RS03120
uniprot id: E0TDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrbL/VirB6 family.
messages: Membrane

314260:PB2503 RS13720
gene id: 314260:PB2503_RS13720
uniprot id: E0TD52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

314260:PB2503 RS13880
gene id: 314260:PB2503_RS13880
uniprot id: E0THM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

314260:PB2503 RS12250
gene id: 314260:PB2503_RS12250
uniprot id: E0TG23
names: Similarity
messages: Belongs to the citrate synthase family.

314260:PB2503 RS08045
gene id: 314260:PB2503_RS08045
uniprot id: E0TBP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

314260:PB2503 RS03680
gene id: 314260:PB2503_RS03680
uniprot id: E0TEM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

314260:PB2503 RS01570
gene id: 314260:PB2503_RS01570
uniprot id: E0TBZ2
names: Similarity
messages: Belongs to the peptidase M13 family.

314260:PB2503 RS02265
gene id: 314260:PB2503_RS02265
uniprot id: E0TCN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

314260:PB2503 RS09860
gene id: 314260:PB2503_RS09860
uniprot id: E0TG18
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

314260:PB2503 RS13150
gene id: 314260:PB2503_RS13150
uniprot id: E0THX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS03115
gene id: 314260:PB2503_RS03115
uniprot id: E0TDN5
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS06515
gene id: 314260:PB2503_RS06515
uniprot id: E0TE95
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

314260:PB2503 RS06830
gene id: 314260:PB2503_RS06830
uniprot id: E0TFD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS04035
gene id: 314260:PB2503_RS04035
uniprot id: E0TF57
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

314260:PB2503 RS06650
gene id: 314260:PB2503_RS06650
uniprot id: E0TEC1
names: Similarity
messages: Belongs to the ros/MucR family.

314260:PB2503 RS02215
gene id: 314260:PB2503_RS02215
uniprot id: E0TCM4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

314260:PB2503 RS08490
gene id: 314260:PB2503_RS08490
uniprot id: E0TCS1
names: Similarity
messages: Belongs to the UPF0234 family.

314260:PB2503 RS12290
gene id: 314260:PB2503_RS12290
uniprot id: E0TG31
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

314260:PB2503 RS00940
gene id: 314260:PB2503_RS00940
uniprot id: E0TBI8
names: Similarity
messages: Belongs to the transglycosylase Slt family.
messages: Belongs to the virb1 family.

314260:PB2503 RS14005
gene id: 314260:PB2503_RS14005
uniprot id: E0TCS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

314260:PB2503 RS10680
gene id: 314260:PB2503_RS10680
uniprot id: E0TC40
names: Similarity
messages: Belongs to the fabD family.

314260:PB2503 RS00835
gene id: 314260:PB2503_RS00835
uniprot id: E0TBG9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

314260:PB2503 RS03325
gene id: 314260:PB2503_RS03325
uniprot id: E0TE13
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

314260:PB2503 RS11050
gene id: 314260:PB2503_RS11050
uniprot id: E0TCY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

314260:PB2503 RS12545
gene id: 314260:PB2503_RS12545
uniprot id: E0TGP6
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

314260:PB2503 RS12880
gene id: 314260:PB2503_RS12880
uniprot id: E0THD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS05370
gene id: 314260:PB2503_RS05370
uniprot id: E0TGZ7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

314260:PB2503 RS11265
gene id: 314260:PB2503_RS11265
uniprot id: E0TDV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS00745
gene id: 314260:PB2503_RS00745
uniprot id: E0TBC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS09160
gene id: 314260:PB2503_RS09160
uniprot id: E0TDS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS13920
gene id: 314260:PB2503_RS13920
uniprot id: E0TET4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

314260:PB2503 RS08760
gene id: 314260:PB2503_RS08760
uniprot id: E0TD90
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

314260:PB2503 RS01965
gene id: 314260:PB2503_RS01965
uniprot id: E0TCD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

314260:PB2503 RS07445
gene id: 314260:PB2503_RS07445
uniprot id: E0TH63
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

314260:PB2503 RS12860
gene id: 314260:PB2503_RS12860
uniprot id: E0TGW0
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

314260:PB2503 RS09995
gene id: 314260:PB2503_RS09995
uniprot id: E0TGN0
names: Subunit
messages: Homodimer.

314260:PB2503 RS12570
gene id: 314260:PB2503_RS12570
uniprot id: E0TGQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

314260:PB2503 RS10225
gene id: 314260:PB2503_RS10225
uniprot id: E0THB7
names: Similarity
messages: Belongs to the peptidase M24B family.

314260:PB2503 RS01080
gene id: 314260:PB2503_RS01080
uniprot id: E0TBL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

314260:PB2503 RS13340
gene id: 314260:PB2503_RS13340
uniprot id: E0TI10
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MntP (TC 9.B.29) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably functions as a manganese efflux pump.

314260:PB2503 RS07720
gene id: 314260:PB2503_RS07720
uniprot id: E0TIB8
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

314260:PB2503 RS05980
gene id: 314260:PB2503_RS05980
uniprot id: E0TI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

314260:PB2503 RS01985
gene id: 314260:PB2503_RS01985
uniprot id: E0TCD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

314260:PB2503 RS02230
gene id: 314260:PB2503_RS02230
uniprot id: E0TCM7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

314260:PB2503 RS01260
gene id: 314260:PB2503_RS01260
uniprot id: E0TBT1
names: Similarity
messages: Belongs to the RecJ family.

314260:PB2503 RS08240
gene id: 314260:PB2503_RS08240
uniprot id: E0TC14
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

314260:PB2503 RS08595
gene id: 314260:PB2503_RS08595
uniprot id: E0TCU2
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

314260:PB2503 RS01765
gene id: 314260:PB2503_RS01765
uniprot id: E0TC91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

314260:PB2503 RS01160
gene id: 314260:PB2503_RS01160
uniprot id: E0TBN0
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.
messages: Toroid-shaped homodecamer, composed of two pentamers of five dimers.

314260:PB2503 RS02150
gene id: 314260:PB2503_RS02150
uniprot id: E0TCL1
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

314260:PB2503 RS07230
gene id: 314260:PB2503_RS07230
uniprot id: E0TGI9
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.

314260:PB2503 RS08010
gene id: 314260:PB2503_RS08010
uniprot id: E0TBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

314260:PB2503 RS08855
gene id: 314260:PB2503_RS08855
uniprot id: E0TDB0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

314260:PB2503 RS10280
gene id: 314260:PB2503_RS10280
uniprot id: E0THC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

314260:PB2503 RS09520
gene id: 314260:PB2503_RS09520
uniprot id: E0TEX3
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

314260:PB2503 RS09625
gene id: 314260:PB2503_RS09625
uniprot id: E0TFG5
names: Similarity
messages: Belongs to the pirin family.

314260:PB2503 RS08300
gene id: 314260:PB2503_RS08300
uniprot id: E0TC26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase D family.
messages: Cytoplasm
messages: Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.

314260:PB2503 RS05740
gene id: 314260:PB2503_RS05740
uniprot id: E0THM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the O-antigen polymerase family.
messages: Membrane

314260:PB2503 RS00380
gene id: 314260:PB2503_RS00380
uniprot id: E0TB47
names: Similarity
messages: Belongs to the BolA/IbaG family.

314260:PB2503 RS08580
gene id: 314260:PB2503_RS08580
uniprot id: E0TCT9
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

314260:PB2503 RS10590
gene id: 314260:PB2503_RS10590
uniprot id: E0TIG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
messages: Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
messages: Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).
messages: Homodimer or monomer when oxidized or reduced, respectively.
messages: chloroplast

314260:PB2503 RS03640
gene id: 314260:PB2503_RS03640
uniprot id: E0TEL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

314260:PB2503 RS02945
gene id: 314260:PB2503_RS02945
uniprot id: E0TDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

314260:PB2503 RS07140
gene id: 314260:PB2503_RS07140
uniprot id: E0TGH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

314260:PB2503 RS11245
gene id: 314260:PB2503_RS11245
uniprot id: E0TDV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell inner membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

314260:PB2503 RS08960
gene id: 314260:PB2503_RS08960
uniprot id: E0TDD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

314260:PB2503 RS12595
gene id: 314260:PB2503_RS12595
uniprot id: E0TGQ6
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS09855
gene id: 314260:PB2503_RS09855
uniprot id: E0TG17
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

314260:PB2503 RS06160
gene id: 314260:PB2503_RS06160
uniprot id: E0TI58
names: Subcellular Location Annotation
messages: Membrane

314260:PB2503 RS09440
gene id: 314260:PB2503_RS09440
uniprot id: E0TEV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

314260:PB2503 RS09905
gene id: 314260:PB2503_RS09905
uniprot id: E0TGL4
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

314260:PB2503 RS06360
gene id: 314260:PB2503_RS06360
uniprot id: E0TI99
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane

314260:PB2503 RS10435
gene id: 314260:PB2503_RS10435
uniprot id: E0THV5
names: Similarity
messages: Belongs to the sterol desaturase family.

314260:PB2503 RS04720
gene id: 314260:PB2503_RS04720
uniprot id: E0TFV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

314260:PB2503 RS07160
gene id: 314260:PB2503_RS07160
uniprot id: E0TGH6
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

314260:PB2503 RS12985
gene id: 314260:PB2503_RS12985
uniprot id: E0THF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane

314260:PB2503 RS03935
gene id: 314260:PB2503_RS03935
uniprot id: E0TES2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

314260:PB2503 RS11875
gene id: 314260:PB2503_RS11875
uniprot id: E0TF45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
messages: Membrane

314260:PB2503 RS08510
gene id: 314260:PB2503_RS08510
uniprot id: E0TCS5
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

314260:PB2503 RS11820
gene id: 314260:PB2503_RS11820
uniprot id: E0TF34
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

314260:PB2503 RS04010
gene id: 314260:PB2503_RS04010
uniprot id: E0TF52
names: Subcellular Location Annotation
messages: Membrane