313595:P700755 RS00515
gene id: 313595:P700755_RS00515
uniprot id: K4I9T0
names: Similarity
messages: Belongs to the peptidase C40 family.

313595:P700755 RS09935
gene id: 313595:P700755_RS09935
uniprot id: K4IEH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

313595:P700755 RS16285
gene id: 313595:P700755_RS16285
uniprot id: K4IXI8
names: Similarity
messages: Belongs to the cysteine dioxygenase family.

313595:P700755 RS00280
gene id: 313595:P700755_RS00280
uniprot id: K4I9N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

313595:P700755 RS17825
gene id: 313595:P700755_RS17825
uniprot id: K4IYE8
names: Similarity
messages: Belongs to the LOG family.

313595:P700755 RS16550
gene id: 313595:P700755_RS16550
uniprot id: K4IIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS14420
gene id: 313595:P700755_RS14420
uniprot id: K4IJ20
names: Similarity
messages: Belongs to the peptidase S8 family.

313595:P700755 RS07180
gene id: 313595:P700755_RS07180
uniprot id: K4IF29
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

313595:P700755 RS01995
gene id: 313595:P700755_RS01995
uniprot id: K4IEE9
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

313595:P700755 RS02690
gene id: 313595:P700755_RS02690
uniprot id: K4IB05
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

313595:P700755 RS13240
gene id: 313595:P700755_RS13240
uniprot id: K4IKI6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

313595:P700755 RS13700
gene id: 313595:P700755_RS13700
uniprot id: K4IW53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

313595:P700755 RS00940
gene id: 313595:P700755_RS00940
uniprot id: K4I9E3
names: Cofactor
messages: Can also use Mn(2+) ion.

313595:P700755 RS09955
gene id: 313595:P700755_RS09955
uniprot id: K4IIQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 100 family.

313595:P700755 RS09845
gene id: 313595:P700755_RS09845
uniprot id: K4IEU9
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

313595:P700755 RS09325
gene id: 313595:P700755_RS09325
uniprot id: K4IIC1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

313595:P700755 RS15480
gene id: 313595:P700755_RS15480
uniprot id: K4IJQ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS07805
gene id: 313595:P700755_RS07805
uniprot id: K4IDU1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS02440
gene id: 313595:P700755_RS02440
uniprot id: K4ICF2
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.

313595:P700755 RS01285
gene id: 313595:P700755_RS01285
uniprot id: K4IP64
names: Similarity
messages: Belongs to the SusD family.

313595:P700755 RS09635
gene id: 313595:P700755_RS09635
uniprot id: K4IGH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS16865
gene id: 313595:P700755_RS16865
uniprot id: K4IIU5
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS01565
gene id: 313595:P700755_RS01565
uniprot id: K4IE55
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS17175
gene id: 313595:P700755_RS17175
uniprot id: K4IIF7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04730
gene id: 313595:P700755_RS04730
uniprot id: K4IDS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

313595:P700755 RS15230
gene id: 313595:P700755_RS15230
uniprot id: K4IHJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

313595:P700755 RS04025
gene id: 313595:P700755_RS04025
uniprot id: K4IQT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

313595:P700755 RS01305
gene id: 313595:P700755_RS01305
uniprot id: K4IA72
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04990
gene id: 313595:P700755_RS04990
uniprot id: K4IC99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

313595:P700755 RS04735
gene id: 313595:P700755_RS04735
uniprot id: K4IC62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

313595:P700755 RS17035
gene id: 313595:P700755_RS17035
uniprot id: K4IKI5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS00625
gene id: 313595:P700755_RS00625
uniprot id: K4I994
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

313595:P700755 RS17705
gene id: 313595:P700755_RS17705
uniprot id: K4IY94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

313595:P700755 RS12435
gene id: 313595:P700755_RS12435
uniprot id: K4IGG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313595:P700755 RS01005
gene id: 313595:P700755_RS01005
uniprot id: K4IDS2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313595:P700755 RS10315
gene id: 313595:P700755_RS10315
uniprot id: K4IGY7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS06280
gene id: 313595:P700755_RS06280
uniprot id: K4ICZ5
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

313595:P700755 RS17595
gene id: 313595:P700755_RS17595
uniprot id: K4IKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS09240
gene id: 313595:P700755_RS09240
uniprot id: K4IG75
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

313595:P700755 RS15205
gene id: 313595:P700755_RS15205
uniprot id: K4IHJ2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

313595:P700755 RS08935
gene id: 313595:P700755_RS08935
uniprot id: K4IEC8
names: Similarity
messages: Belongs to the RecJ family.

313595:P700755 RS02985
gene id: 313595:P700755_RS02985
uniprot id: K4IB60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

313595:P700755 RS16405
gene id: 313595:P700755_RS16405
uniprot id: K4IIM9
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

313595:P700755 RS04625
gene id: 313595:P700755_RS04625
uniprot id: K4IBJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

313595:P700755 RS01555
gene id: 313595:P700755_RS01555
uniprot id: K4IAC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS13350
gene id: 313595:P700755_RS13350
uniprot id: K4IGZ4
names: Similarity
messages: Belongs to the glutamate synthase family.

313595:P700755 RS05940
gene id: 313595:P700755_RS05940
uniprot id: K4IRX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

313595:P700755 RS15350
gene id: 313595:P700755_RS15350
uniprot id: K4IX40
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

313595:P700755 RS09315
gene id: 313595:P700755_RS09315
uniprot id: K4IEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS18555
gene id: 313595:P700755_RS18555
uniprot id: K4I9X0
names: Similarity
messages: Belongs to the ice-binding protein family.

313595:P700755 RS02485
gene id: 313595:P700755_RS02485
uniprot id: K4IAD4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

313595:P700755 RS14490
gene id: 313595:P700755_RS14490
uniprot id: K4IWJ1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313595:P700755 RS04775
gene id: 313595:P700755_RS04775
uniprot id: K4IBN2
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS13125
gene id: 313595:P700755_RS13125
uniprot id: K4IVU9
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

313595:P700755 RS03180
gene id: 313595:P700755_RS03180
uniprot id: K4IF28
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16740
gene id: 313595:P700755_RS16740
uniprot id: K4IMG4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

313595:P700755 RS12205
gene id: 313595:P700755_RS12205
uniprot id: K4IHW4
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00830
gene id: 313595:P700755_RS00830
uniprot id: K4IDN7
names: Similarity
messages: Belongs to the phosphohexose mutase family.

313595:P700755 RS16540
gene id: 313595:P700755_RS16540
uniprot id: K4II40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

313595:P700755 RS15975
gene id: 313595:P700755_RS15975
uniprot id: K4IXD9
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16395
gene id: 313595:P700755_RS16395
uniprot id: K4II23
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09695
gene id: 313595:P700755_RS09695
uniprot id: K4IER1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VirD4/TraG family.
messages: Membrane

313595:P700755 RS11770
gene id: 313595:P700755_RS11770
uniprot id: K4IG08
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313595:P700755 RS03175
gene id: 313595:P700755_RS03175
uniprot id: K4IQC2
names: Similarity
messages: Belongs to the NusB family.

313595:P700755 RS05535
gene id: 313595:P700755_RS05535
uniprot id: K4IGE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS02770
gene id: 313595:P700755_RS02770
uniprot id: K4IB19
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS17620
gene id: 313595:P700755_RS17620
uniprot id: K4IKV5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

313595:P700755 RS15330
gene id: 313595:P700755_RS15330
uniprot id: K4ILS2
names: Similarity
messages: Belongs to the thioesterase PaaI family.

313595:P700755 RS01885
gene id: 313595:P700755_RS01885
uniprot id: K4IAI5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

313595:P700755 RS07685
gene id: 313595:P700755_RS07685
uniprot id: K4ISV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS09560
gene id: 313595:P700755_RS09560
uniprot id: K4IGF6
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

313595:P700755 RS12050
gene id: 313595:P700755_RS12050
uniprot id: K4IFR5
names: Similarity
messages: Belongs to the group II decarboxylase family.

313595:P700755 RS08610
gene id: 313595:P700755_RS08610
uniprot id: K4II02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS07240
gene id: 313595:P700755_RS07240
uniprot id: K4IDH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

313595:P700755 RS02670
gene id: 313595:P700755_RS02670
uniprot id: K4IB01
names: Similarity
messages: Belongs to the IMPACT family.

313595:P700755 RS09235
gene id: 313595:P700755_RS09235
uniprot id: K4IE12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

313595:P700755 RS20760
gene id: 313595:P700755_RS20760
uniprot id: K4IUL2
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

313595:P700755 RS03195
gene id: 313595:P700755_RS03195
uniprot id: K4IB95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

313595:P700755 RS15740
gene id: 313595:P700755_RS15740
uniprot id: K4ILZ2
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

313595:P700755 RS03980
gene id: 313595:P700755_RS03980
uniprot id: K4IB52
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

313595:P700755 RS11820
gene id: 313595:P700755_RS11820
uniprot id: K4IV20
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

313595:P700755 RS16665
gene id: 313595:P700755_RS16665
uniprot id: K4IXP3
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS07885
gene id: 313595:P700755_RS07885
uniprot id: K4ISY3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

313595:P700755 RS06185
gene id: 313595:P700755_RS06185
uniprot id: K4IS19
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

313595:P700755 RS10380
gene id: 313595:P700755_RS10380
uniprot id: K4IIX9
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10510
gene id: 313595:P700755_RS10510
uniprot id: K4IEV7
names: Similarity
messages: Belongs to the MreC family.

313595:P700755 RS07495
gene id: 313595:P700755_RS07495
uniprot id: K4IDP3
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09135
gene id: 313595:P700755_RS09135
uniprot id: K4IG53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

313595:P700755 RS15620
gene id: 313595:P700755_RS15620
uniprot id: K4ILW8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS14385
gene id: 313595:P700755_RS14385
uniprot id: K4IL51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

313595:P700755 RS17120
gene id: 313595:P700755_RS17120
uniprot id: K4IMP2
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS06295
gene id: 313595:P700755_RS06295
uniprot id: K4ICF4
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

313595:P700755 RS11970
gene id: 313595:P700755_RS11970
uniprot id: K4IV53
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

313595:P700755 RS08895
gene id: 313595:P700755_RS08895
uniprot id: K4II38
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15720
gene id: 313595:P700755_RS15720
uniprot id: K4IHS3
names: Similarity
messages: Belongs to the ParB family.

313595:P700755 RS17060
gene id: 313595:P700755_RS17060
uniprot id: K4IKJ1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS13000
gene id: 313595:P700755_RS13000
uniprot id: K4IGD2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313595:P700755 RS08675
gene id: 313595:P700755_RS08675
uniprot id: K4IE86
names: Similarity
messages: Belongs to the Skp family.

313595:P700755 RS01860
gene id: 313595:P700755_RS01860
uniprot id: K4IAI0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

313595:P700755 RS11210
gene id: 313595:P700755_RS11210
uniprot id: K4IUR1
names: Similarity
messages: Belongs to the asparaginase 1 family.

313595:P700755 RS15860
gene id: 313595:P700755_RS15860
uniprot id: K4IXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS14360
gene id: 313595:P700755_RS14360
uniprot id: K4IL45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

313595:P700755 RS02005
gene id: 313595:P700755_RS02005
uniprot id: K4IC35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

313595:P700755 RS15260
gene id: 313595:P700755_RS15260
uniprot id: K4IJL9
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

313595:P700755 RS13085
gene id: 313595:P700755_RS13085
uniprot id: K4IVU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS06130
gene id: 313595:P700755_RS06130
uniprot id: K4ICW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

313595:P700755 RS04895
gene id: 313595:P700755_RS04895
uniprot id: K4IRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS12425
gene id: 313595:P700755_RS12425
uniprot id: K4IFY1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313595:P700755 RS04660
gene id: 313595:P700755_RS04660
uniprot id: K4IC50
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

313595:P700755 RS18305
gene id: 313595:P700755_RS18305
uniprot id: K4IJQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS13030
gene id: 313595:P700755_RS13030
uniprot id: K4IVT3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

313595:P700755 RS04800
gene id: 313595:P700755_RS04800
uniprot id: K4IBN7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

313595:P700755 RS09480
gene id: 313595:P700755_RS09480
uniprot id: K4IE69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

313595:P700755 RS12930
gene id: 313595:P700755_RS12930
uniprot id: K4IGB9
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

313595:P700755 RS02920
gene id: 313595:P700755_RS02920
uniprot id: K4IEZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

313595:P700755 RS15595
gene id: 313595:P700755_RS15595
uniprot id: K4IHQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

313595:P700755 RS16670
gene id: 313595:P700755_RS16670
uniprot id: K4IMF1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

313595:P700755 RS04880
gene id: 313595:P700755_RS04880
uniprot id: K4IBP8
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

313595:P700755 RS14815
gene id: 313595:P700755_RS14815
uniprot id: K4IWQ9
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

313595:P700755 RS06245
gene id: 313595:P700755_RS06245
uniprot id: K4ICE0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

313595:P700755 RS01845
gene id: 313595:P700755_RS01845
uniprot id: K4IEB5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the adenylate cyclase family. DacA/CdaA subfamily.
messages: Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably a homodimer.

313595:P700755 RS06090
gene id: 313595:P700755_RS06090
uniprot id: K4IGQ0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS08765
gene id: 313595:P700755_RS08765
uniprot id: K4IE99
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313595:P700755 RS02915
gene id: 313595:P700755_RS02915
uniprot id: K4IQ81
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

313595:P700755 RS16610
gene id: 313595:P700755_RS16610
uniprot id: K4IXN5
names: Similarity
messages: Belongs to the Dps family.

313595:P700755 RS10665
gene id: 313595:P700755_RS10665
uniprot id: K4IH42
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the ferredoxin--NADP reductase type 2 family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

313595:P700755 RS05325
gene id: 313595:P700755_RS05325
uniprot id: K4IE34
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS04675
gene id: 313595:P700755_RS04675
uniprot id: K4IBM0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

313595:P700755 RS14050
gene id: 313595:P700755_RS14050
uniprot id: K4IWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

313595:P700755 RS17050
gene id: 313595:P700755_RS17050
uniprot id: K4IMN1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15625
gene id: 313595:P700755_RS15625
uniprot id: K4IHQ5
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

313595:P700755 RS00770
gene id: 313595:P700755_RS00770
uniprot id: K4I9X5
names: Similarity
messages: Belongs to the ice-binding protein family.

313595:P700755 RS14045
gene id: 313595:P700755_RS14045
uniprot id: K4IHB9
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10740
gene id: 313595:P700755_RS10740
uniprot id: K4IFF6
names: Similarity
messages: Belongs to the DtxR/MntR family.

313595:P700755 RS15705
gene id: 313595:P700755_RS15705
uniprot id: K4IIB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

313595:P700755 RS02065
gene id: 313595:P700755_RS02065
uniprot id: K4IA70
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

313595:P700755 RS07060
gene id: 313595:P700755_RS07060
uniprot id: K4IF01
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

313595:P700755 RS07535
gene id: 313595:P700755_RS07535
uniprot id: K4IHI8
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

313595:P700755 RS04415
gene id: 313595:P700755_RS04415
uniprot id: K4IR12
names: Similarity
messages: Belongs to the heat shock protein 70 family.

313595:P700755 RS11905
gene id: 313595:P700755_RS11905
uniprot id: K4IFN1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

313595:P700755 RS11345
gene id: 313595:P700755_RS11345
uniprot id: K4IJF7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS04580
gene id: 313595:P700755_RS04580
uniprot id: K4IBI1
names: Similarity
messages: Belongs to the citrate synthase family.

313595:P700755 RS16055
gene id: 313595:P700755_RS16055
uniprot id: K4IM50
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

313595:P700755 RS06070
gene id: 313595:P700755_RS06070
uniprot id: K4IGP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS16555
gene id: 313595:P700755_RS16555
uniprot id: K4IXM7
names: Similarity
messages: Belongs to the RutC family.

313595:P700755 RS01820
gene id: 313595:P700755_RS01820
uniprot id: K4IEA7
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

313595:P700755 RS11155
gene id: 313595:P700755_RS11155
uniprot id: K4IHC5
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

313595:P700755 RS06190
gene id: 313595:P700755_RS06190
uniprot id: K4IGR9
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

313595:P700755 RS05065
gene id: 313595:P700755_RS05065
uniprot id: K4ICB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS03295
gene id: 313595:P700755_RS03295
uniprot id: K4IAR6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS16280
gene id: 313595:P700755_RS16280
uniprot id: K4IIK6
names: Similarity
messages: Belongs to the group II decarboxylase family.

313595:P700755 RS08270
gene id: 313595:P700755_RS08270
uniprot id: K4IT38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

313595:P700755 RS00900
gene id: 313595:P700755_RS00900
uniprot id: K4INX8
names: Similarity
messages: Belongs to the nitroreductase family.

313595:P700755 RS06705
gene id: 313595:P700755_RS06705
uniprot id: K4IH12
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

313595:P700755 RS16530
gene id: 313595:P700755_RS16530
uniprot id: K4IXM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

313595:P700755 RS10175
gene id: 313595:P700755_RS10175
uniprot id: K4IEP9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS16355
gene id: 313595:P700755_RS16355
uniprot id: K4IIM0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS11505
gene id: 313595:P700755_RS11505
uniprot id: K4IJI2
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

313595:P700755 RS14445
gene id: 313595:P700755_RS14445
uniprot id: K4IJ24
names: Function
names: Similarity
messages: Belongs to the TenA family.
messages: Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway.

313595:P700755 RS02040
gene id: 313595:P700755_RS02040
uniprot id: K4IA57
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

313595:P700755 RS13065
gene id: 313595:P700755_RS13065
uniprot id: K4IKF4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

313595:P700755 RS06065
gene id: 313595:P700755_RS06065
uniprot id: K4IRZ5
names: Similarity
messages: Belongs to the SusD family.

313595:P700755 RS00310
gene id: 313595:P700755_RS00310
uniprot id: K4INL4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

313595:P700755 RS12405
gene id: 313595:P700755_RS12405
uniprot id: K4IHZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

313595:P700755 RS00510
gene id: 313595:P700755_RS00510
uniprot id: K4IB97
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

313595:P700755 RS01630
gene id: 313595:P700755_RS01630
uniprot id: K4IAD6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

313595:P700755 RS09425
gene id: 313595:P700755_RS09425
uniprot id: K4IIE2
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

313595:P700755 RS13785
gene id: 313595:P700755_RS13785
uniprot id: K4IIQ6
names: Similarity
messages: Belongs to the universal stress protein A family.

313595:P700755 RS03795
gene id: 313595:P700755_RS03795
uniprot id: K4IQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

313595:P700755 RS04535
gene id: 313595:P700755_RS04535
uniprot id: K4IDJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS10455
gene id: 313595:P700755_RS10455
uniprot id: K4IUC5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

313595:P700755 RS03625
gene id: 313595:P700755_RS03625
uniprot id: K4ID17
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS04220
gene id: 313595:P700755_RS04220
uniprot id: K4IFN0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16465
gene id: 313595:P700755_RS16465
uniprot id: K4IMB5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the N-terminal section; belongs to the DHBP synthase family.

313595:P700755 RS11720
gene id: 313595:P700755_RS11720
uniprot id: K4IHL7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

313595:P700755 RS12045
gene id: 313595:P700755_RS12045
uniprot id: K4IJU1
names: Similarity
messages: Belongs to the BshC family.

313595:P700755 RS01315
gene id: 313595:P700755_RS01315
uniprot id: K4IDZ3
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

313595:P700755 RS13925
gene id: 313595:P700755_RS13925
uniprot id: K4IGS1
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

313595:P700755 RS15670
gene id: 313595:P700755_RS15670
uniprot id: K4IHR4
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

313595:P700755 RS14630
gene id: 313595:P700755_RS14630
uniprot id: K4IJ60
names: Similarity
messages: Belongs to the peptidase S33 family.

313595:P700755 RS04975
gene id: 313595:P700755_RS04975
uniprot id: K4IG50
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

313595:P700755 RS11830
gene id: 313595:P700755_RS11830
uniprot id: K4IFL5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

313595:P700755 RS05905
gene id: 313595:P700755_RS05905
uniprot id: K4IED6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS12100
gene id: 313595:P700755_RS12100
uniprot id: K4IFS4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

313595:P700755 RS12445
gene id: 313595:P700755_RS12445
uniprot id: K4IK28
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

313595:P700755 RS05105
gene id: 313595:P700755_RS05105
uniprot id: K4IBT7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS12695
gene id: 313595:P700755_RS12695
uniprot id: K4IGP0
names: Similarity
messages: Belongs to the RelE toxin family.

313595:P700755 RS05530
gene id: 313595:P700755_RS05530
uniprot id: K4IRP6
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

313595:P700755 RS02540
gene id: 313595:P700755_RS02540
uniprot id: K4ICH1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

313595:P700755 RS12105
gene id: 313595:P700755_RS12105
uniprot id: K4IG83
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS11355
gene id: 313595:P700755_RS11355
uniprot id: K4IHF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

313595:P700755 RS16420
gene id: 313595:P700755_RS16420
uniprot id: K4II26
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

313595:P700755 RS05680
gene id: 313595:P700755_RS05680
uniprot id: K4ICN1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

313595:P700755 RS06930
gene id: 313595:P700755_RS06930
uniprot id: K4ISE0
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

313595:P700755 RS16710
gene id: 313595:P700755_RS16710
uniprot id: K4IIS2
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

313595:P700755 RS00395
gene id: 313595:P700755_RS00395
uniprot id: K4I961
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

313595:P700755 RS04610
gene id: 313595:P700755_RS04610
uniprot id: K4IDL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

313595:P700755 RS17640
gene id: 313595:P700755_RS17640
uniprot id: K4IIP9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS11825
gene id: 313595:P700755_RS11825
uniprot id: K4IJN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

313595:P700755 RS05830
gene id: 313595:P700755_RS05830
uniprot id: K4IEC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

313595:P700755 RS01535
gene id: 313595:P700755_RS01535
uniprot id: K4IPC3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS06300
gene id: 313595:P700755_RS06300
uniprot id: K4IEK6
names: Similarity
messages: Belongs to the CIA30 family.

313595:P700755 RS19080
gene id: 313595:P700755_RS19080
uniprot id: K4IFW0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

313595:P700755 RS11935
gene id: 313595:P700755_RS11935
uniprot id: K4IHQ8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

313595:P700755 RS13390
gene id: 313595:P700755_RS13390
uniprot id: K4IGJ5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15615
gene id: 313595:P700755_RS15615
uniprot id: K4IX78
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

313595:P700755 RS10635
gene id: 313595:P700755_RS10635
uniprot id: K4IEY1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09255
gene id: 313595:P700755_RS09255
uniprot id: K4IIA7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

313595:P700755 RS14415
gene id: 313595:P700755_RS14415
uniprot id: K4IH19
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

313595:P700755 RS01780
gene id: 313595:P700755_RS01780
uniprot id: K4IAG2
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS15140
gene id: 313595:P700755_RS15140
uniprot id: K4ILM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

313595:P700755 RS01875
gene id: 313595:P700755_RS01875
uniprot id: K4I9Z5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS11655
gene id: 313595:P700755_RS11655
uniprot id: K4IUZ0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10785
gene id: 313595:P700755_RS10785
uniprot id: K4IH62
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS02870
gene id: 313595:P700755_RS02870
uniprot id: K4IB37
names: Similarity
messages: Belongs to the peptidase S9C family.

313595:P700755 RS12515
gene id: 313595:P700755_RS12515
uniprot id: K4IK44
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS01585
gene id: 313595:P700755_RS01585
uniprot id: K4IPD3
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

313595:P700755 RS17775
gene id: 313595:P700755_RS17775
uniprot id: K4IJE2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

313595:P700755 RS09250
gene id: 313595:P700755_RS09250
uniprot id: K4ITK6
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

313595:P700755 RS07095
gene id: 313595:P700755_RS07095
uniprot id: K4ISH2
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

313595:P700755 RS06205
gene id: 313595:P700755_RS06205
uniprot id: K4ICY2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

313595:P700755 RS10485
gene id: 313595:P700755_RS10485
uniprot id: K4IEV2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

313595:P700755 RS01855
gene id: 313595:P700755_RS01855
uniprot id: K4IC03
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS13365
gene id: 313595:P700755_RS13365
uniprot id: K4IGJ2
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

313595:P700755 RS03755
gene id: 313595:P700755_RS03755
uniprot id: K4IB12
names: Similarity
messages: Belongs to the nitroreductase family.

313595:P700755 RS01140
gene id: 313595:P700755_RS01140
uniprot id: K4IP28
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16800
gene id: 313595:P700755_RS16800
uniprot id: K4II86
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

313595:P700755 RS09455
gene id: 313595:P700755_RS09455
uniprot id: K4IE64
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS16025
gene id: 313595:P700755_RS16025
uniprot id: K4IXE7
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

313595:P700755 RS04595
gene id: 313595:P700755_RS04595
uniprot id: K4IR55
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

313595:P700755 RS00330
gene id: 313595:P700755_RS00330
uniprot id: K4I9P5
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

313595:P700755 RS12615
gene id: 313595:P700755_RS12615
uniprot id: K4IVL5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 1 copper ion per subunit, denoted as copper B.
messages: Binds 2 heme groups per subunit, denoted as high- and low-spin.
messages: Membrane

313595:P700755 RS09890
gene id: 313595:P700755_RS09890
uniprot id: K4IGM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS11800
gene id: 313595:P700755_RS11800
uniprot id: K4IFK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

313595:P700755 RS04780
gene id: 313595:P700755_RS04780
uniprot id: K4IDT5
names: Caution
names: Similarity
messages: Belongs to the peptidase S8 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04720
gene id: 313595:P700755_RS04720
uniprot id: K4IG12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

313595:P700755 RS03905
gene id: 313595:P700755_RS03905
uniprot id: K4IFG9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS04795
gene id: 313595:P700755_RS04795
uniprot id: K4IG23
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00275
gene id: 313595:P700755_RS00275
uniprot id: K4IB55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

313595:P700755 RS01335
gene id: 313595:P700755_RS01335
uniprot id: K4IA77
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

313595:P700755 RS15745
gene id: 313595:P700755_RS15745
uniprot id: K4IHS6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

313595:P700755 RS07660
gene id: 313595:P700755_RS07660
uniprot id: K4ISU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

313595:P700755 RS12745
gene id: 313595:P700755_RS12745
uniprot id: K4IGP8
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS14355
gene id: 313595:P700755_RS14355
uniprot id: K4IWG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Forms oligomers.
messages: nucleoid

313595:P700755 RS18300
gene id: 313595:P700755_RS18300
uniprot id: K4ILB1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

313595:P700755 RS09375
gene id: 313595:P700755_RS09375
uniprot id: K4IID0
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

313595:P700755 RS17480
gene id: 313595:P700755_RS17480
uniprot id: K4IY43
names: Similarity
messages: Belongs to the YjiK family.

313595:P700755 RS10710
gene id: 313595:P700755_RS10710
uniprot id: K4IEZ3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS14395
gene id: 313595:P700755_RS14395
uniprot id: K4IJ14
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS11250
gene id: 313595:P700755_RS11250
uniprot id: K4IF98
names: Similarity
messages: Belongs to the sigma-54 factor family.

313595:P700755 RS12455
gene id: 313595:P700755_RS12455
uniprot id: K4II06
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

313595:P700755 RS07175
gene id: 313595:P700755_RS07175
uniprot id: K4ICY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

313595:P700755 RS08945
gene id: 313595:P700755_RS08945
uniprot id: K4II47
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS13525
gene id: 313595:P700755_RS13525
uniprot id: K4IGL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

313595:P700755 RS02850
gene id: 313595:P700755_RS02850
uniprot id: K4IQ67
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

313595:P700755 RS13725
gene id: 313595:P700755_RS13725
uniprot id: K4IGP2
names: Similarity
messages: Belongs to the FPG family.

313595:P700755 RS10095
gene id: 313595:P700755_RS10095
uniprot id: K4IIT6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS14430
gene id: 313595:P700755_RS14430
uniprot id: K4IWI1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

313595:P700755 RS04405
gene id: 313595:P700755_RS04405
uniprot id: K4IDH3
names: Similarity
messages: Belongs to the AAA ATPase family.

313595:P700755 RS03110
gene id: 313595:P700755_RS03110
uniprot id: K4IQB3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

313595:P700755 RS02665
gene id: 313595:P700755_RS02665
uniprot id: K4ICJ6
names: Function
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

313595:P700755 RS00050
gene id: 313595:P700755_RS00050
uniprot id: K4IB13
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15545
gene id: 313595:P700755_RS15545
uniprot id: K4IX71
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

313595:P700755 RS13695
gene id: 313595:P700755_RS13695
uniprot id: K4IH51
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

313595:P700755 RS08730
gene id: 313595:P700755_RS08730
uniprot id: K4IDQ5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05965
gene id: 313595:P700755_RS05965
uniprot id: K4IRX5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS02605
gene id: 313595:P700755_RS02605
uniprot id: K4IES6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

313595:P700755 RS05090
gene id: 313595:P700755_RS05090
uniprot id: K4ICB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS00615
gene id: 313595:P700755_RS00615
uniprot id: K4INS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

313595:P700755 RS02435
gene id: 313595:P700755_RS02435
uniprot id: K4IAC7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

313595:P700755 RS02380
gene id: 313595:P700755_RS02380
uniprot id: K4IEN8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS02400
gene id: 313595:P700755_RS02400
uniprot id: K4IPX8
names: Cofactor
names: Similarity
messages: Belongs to the ApbE family.
messages: Magnesium. Can also use manganese.

313595:P700755 RS10400
gene id: 313595:P700755_RS10400
uniprot id: K4IUB7
names: Similarity
messages: Belongs to the polysaccharide synthase family.

313595:P700755 RS05245
gene id: 313595:P700755_RS05245
uniprot id: K4IRK4
names: Similarity
messages: Belongs to the peptidase S8 family.

313595:P700755 RS02120
gene id: 313595:P700755_RS02120
uniprot id: K4IC94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urocanase family.
messages: Binds 1 NAD(+) per subunit.
messages: Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS14795
gene id: 313595:P700755_RS14795
uniprot id: K4ILE0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

313595:P700755 RS11735
gene id: 313595:P700755_RS11735
uniprot id: K4IJM1
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

313595:P700755 RS10730
gene id: 313595:P700755_RS10730
uniprot id: K4IJ43
names: Similarity
messages: Belongs to the transglycosylase Slt family.

313595:P700755 RS06165
gene id: 313595:P700755_RS06165
uniprot id: K4IGR5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS13035
gene id: 313595:P700755_RS13035
uniprot id: K4IKF0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313595:P700755 RS12740
gene id: 313595:P700755_RS12740
uniprot id: K4II78
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS01525
gene id: 313595:P700755_RS01525
uniprot id: K4IBS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

313595:P700755 RS17490
gene id: 313595:P700755_RS17490
uniprot id: K4IIL8
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS11700
gene id: 313595:P700755_RS11700
uniprot id: K4IFY8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS01905
gene id: 313595:P700755_RS01905
uniprot id: K4IC13
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

313595:P700755 RS06030
gene id: 313595:P700755_RS06030
uniprot id: K4IEG1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10620
gene id: 313595:P700755_RS10620
uniprot id: K4IFD2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS08350
gene id: 313595:P700755_RS08350
uniprot id: K4IHW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

313595:P700755 RS12030
gene id: 313595:P700755_RS12030
uniprot id: K4IHS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

313595:P700755 RS03085
gene id: 313595:P700755_RS03085
uniprot id: K4IQA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

313595:P700755 RS17615
gene id: 313595:P700755_RS17615
uniprot id: K4IIP5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS12040
gene id: 313595:P700755_RS12040
uniprot id: K4IV66
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS00245
gene id: 313595:P700755_RS00245
uniprot id: K4I932
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS06040
gene id: 313595:P700755_RS06040
uniprot id: K4IRZ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

313595:P700755 RS15755
gene id: 313595:P700755_RS15755
uniprot id: K4IIC4
names: Similarity
messages: Belongs to the DEAD box helicase family.

313595:P700755 RS17800
gene id: 313595:P700755_RS17800
uniprot id: K4IYD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS17020
gene id: 313595:P700755_RS17020
uniprot id: K4IXV7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS13780
gene id: 313595:P700755_RS13780
uniprot id: K4IGQ2
names: Similarity
messages: Belongs to the universal stress protein A family.

313595:P700755 RS03095
gene id: 313595:P700755_RS03095
uniprot id: K4IAN7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS17840
gene id: 313595:P700755_RS17840
uniprot id: K4IL35
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

313595:P700755 RS05110
gene id: 313595:P700755_RS05110
uniprot id: K4IDZ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS07755
gene id: 313595:P700755_RS07755
uniprot id: K4IDT3
names: Similarity
messages: Belongs to the YicC/YloC family.

313595:P700755 RS00410
gene id: 313595:P700755_RS00410
uniprot id: K4INN4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS12025
gene id: 313595:P700755_RS12025
uniprot id: K4IJT6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

313595:P700755 RS01570
gene id: 313595:P700755_RS01570
uniprot id: K4I9T3
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

313595:P700755 RS17420
gene id: 313595:P700755_RS17420
uniprot id: K4IKR5
names: Similarity
messages: Belongs to the ArsC family.

313595:P700755 RS11180
gene id: 313595:P700755_RS11180
uniprot id: K4IHD0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

313595:P700755 RS00885
gene id: 313595:P700755_RS00885
uniprot id: K4I9D2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

313595:P700755 RS03125
gene id: 313595:P700755_RS03125
uniprot id: K4IAP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

313595:P700755 RS00305
gene id: 313595:P700755_RS00305
uniprot id: K4I9P1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

313595:P700755 RS16475
gene id: 313595:P700755_RS16475
uniprot id: K4IK77
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313595:P700755 RS04710
gene id: 313595:P700755_RS04710
uniprot id: K4IC58
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

313595:P700755 RS09045
gene id: 313595:P700755_RS09045
uniprot id: K4ITH1
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

313595:P700755 RS01830
gene id: 313595:P700755_RS01830
uniprot id: K4IBZ5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS13025
gene id: 313595:P700755_RS13025
uniprot id: K4IGU0
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

313595:P700755 RS17500
gene id: 313595:P700755_RS17500
uniprot id: K4IJ81
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS12180
gene id: 313595:P700755_RS12180
uniprot id: K4IHV7
names: Similarity
messages: Belongs to the Skp family.

313595:P700755 RS15420
gene id: 313595:P700755_RS15420
uniprot id: K4ILT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS08645
gene id: 313595:P700755_RS08645
uniprot id: K4IFW5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00620
gene id: 313595:P700755_RS00620
uniprot id: K4IDK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS00845
gene id: 313595:P700755_RS00845
uniprot id: K4I9Y9
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS06250
gene id: 313595:P700755_RS06250
uniprot id: K4IEJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

313595:P700755 RS02795
gene id: 313595:P700755_RS02795
uniprot id: K4IB23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

313595:P700755 RS16430
gene id: 313595:P700755_RS16430
uniprot id: K4IIN4
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

313595:P700755 RS07585
gene id: 313595:P700755_RS07585
uniprot id: K4ID82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm
messages: Degrades oligopeptides.

313595:P700755 RS02510
gene id: 313595:P700755_RS02510
uniprot id: K4IAD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

313595:P700755 RS09245
gene id: 313595:P700755_RS09245
uniprot id: K4IEI0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

313595:P700755 RS03200
gene id: 313595:P700755_RS03200
uniprot id: K4IQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

313595:P700755 RS10045
gene id: 313595:P700755_RS10045
uniprot id: K4IIT1
names: Similarity
messages: Belongs to the ArsC family.

313595:P700755 RS16680
gene id: 313595:P700755_RS16680
uniprot id: K4IKA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS02135
gene id: 313595:P700755_RS02135
uniprot id: K4IEK3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS03600
gene id: 313595:P700755_RS03600
uniprot id: K4IBG5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

313595:P700755 RS02520
gene id: 313595:P700755_RS02520
uniprot id: K4IAX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

313595:P700755 RS00270
gene id: 313595:P700755_RS00270
uniprot id: K4I936
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS15320
gene id: 313595:P700755_RS15320
uniprot id: K4II54
names: Subcellular Location Annotation
messages: Secreted

313595:P700755 RS10535
gene id: 313595:P700755_RS10535
uniprot id: K4IEW2
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

313595:P700755 RS03780
gene id: 313595:P700755_RS03780
uniprot id: K4IB18
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

313595:P700755 RS03865
gene id: 313595:P700755_RS03865
uniprot id: K4IBK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

313595:P700755 RS07800
gene id: 313595:P700755_RS07800
uniprot id: K4IFH8
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.

313595:P700755 RS04475
gene id: 313595:P700755_RS04475
uniprot id: K4IFT3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS17070
gene id: 313595:P700755_RS17070
uniprot id: K4IXW7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16460
gene id: 313595:P700755_RS16460
uniprot id: K4IXL5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS04630
gene id: 313595:P700755_RS04630
uniprot id: K4IDL7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

313595:P700755 RS01810
gene id: 313595:P700755_RS01810
uniprot id: K4IAG8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

313595:P700755 RS09050
gene id: 313595:P700755_RS09050
uniprot id: K4II66
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

313595:P700755 RS07090
gene id: 313595:P700755_RS07090
uniprot id: K4IDE4
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

313595:P700755 RS06195
gene id: 313595:P700755_RS06195
uniprot id: K4ICC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

313595:P700755 RS05675
gene id: 313595:P700755_RS05675
uniprot id: K4IE93
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

313595:P700755 RS12015
gene id: 313595:P700755_RS12015
uniprot id: K4IG58
names: Similarity
messages: Belongs to the CinA family.

313595:P700755 RS17515
gene id: 313595:P700755_RS17515
uniprot id: K4IIM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

313595:P700755 RS16595
gene id: 313595:P700755_RS16595
uniprot id: K4IK91
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

313595:P700755 RS02430
gene id: 313595:P700755_RS02430
uniprot id: K4IEP6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16255
gene id: 313595:P700755_RS16255
uniprot id: K4IIK1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313595:P700755 RS04585
gene id: 313595:P700755_RS04585
uniprot id: K4IDK7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

313595:P700755 RS02165
gene id: 313595:P700755_RS02165
uniprot id: K4IA86
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

313595:P700755 RS00960
gene id: 313595:P700755_RS00960
uniprot id: K4IDQ9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

313595:P700755 RS01950
gene id: 313595:P700755_RS01950
uniprot id: K4IA12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS14410
gene id: 313595:P700755_RS14410
uniprot id: K4IL56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell inner membrane
messages: Self-interacts. Interacts with FtsZ.

313595:P700755 RS08275
gene id: 313595:P700755_RS08275
uniprot id: K4IHV0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

313595:P700755 RS12185
gene id: 313595:P700755_RS12185
uniprot id: K4IGA3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

313595:P700755 RS00115
gene id: 313595:P700755_RS00115
uniprot id: K4I912
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS02320
gene id: 313595:P700755_RS02320
uniprot id: K4IAT6
names: Similarity
messages: Belongs to the ArsC family.

313595:P700755 RS17385
gene id: 313595:P700755_RS17385
uniprot id: K4IIK0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS16915
gene id: 313595:P700755_RS16915
uniprot id: K4IIV5
names: Similarity
messages: Belongs to the peptidase S24 family.

313595:P700755 RS13685
gene id: 313595:P700755_RS13685
uniprot id: K4IGN8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

313595:P700755 RS10515
gene id: 313595:P700755_RS10515
uniprot id: K4IH20
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS11870
gene id: 313595:P700755_RS11870
uniprot id: K4IV32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

313595:P700755 RS11275
gene id: 313595:P700755_RS11275
uniprot id: K4IFA3
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

313595:P700755 RS08690
gene id: 313595:P700755_RS08690
uniprot id: K4IDQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

313595:P700755 RS11845
gene id: 313595:P700755_RS11845
uniprot id: K4IV25
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

313595:P700755 RS01270
gene id: 313595:P700755_RS01270
uniprot id: K4I9L7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

313595:P700755 RS03575
gene id: 313595:P700755_RS03575
uniprot id: K4IQK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS09915
gene id: 313595:P700755_RS09915
uniprot id: K4IGN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

313595:P700755 RS07730
gene id: 313595:P700755_RS07730
uniprot id: K4IDS9
names: Similarity
messages: Belongs to the Skp family.

313595:P700755 RS13405
gene id: 313595:P700755_RS13405
uniprot id: K4IW00
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.

313595:P700755 RS17720
gene id: 313595:P700755_RS17720
uniprot id: K4IKY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

313595:P700755 RS01880
gene id: 313595:P700755_RS01880
uniprot id: K4IC08
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

313595:P700755 RS02155
gene id: 313595:P700755_RS02155
uniprot id: K4IPT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS16480
gene id: 313595:P700755_RS16480
uniprot id: K4IIP3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

313595:P700755 RS07890
gene id: 313595:P700755_RS07890
uniprot id: K4IHP5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS07215
gene id: 313595:P700755_RS07215
uniprot id: K4IDG9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

313595:P700755 RS08095
gene id: 313595:P700755_RS08095
uniprot id: K4IT13
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313595:P700755 RS01740
gene id: 313595:P700755_RS01740
uniprot id: K4IE90
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

313595:P700755 RS16415
gene id: 313595:P700755_RS16415
uniprot id: K4IMA6
names: Similarity
messages: Belongs to the arginase family.

313595:P700755 RS01900
gene id: 313595:P700755_RS01900
uniprot id: K4IA01
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00700
gene id: 313595:P700755_RS00700
uniprot id: K4I9A7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Brp/Blh beta-carotene diooxygenase family.
messages: Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS06755
gene id: 313595:P700755_RS06755
uniprot id: K4IH24
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS06435
gene id: 313595:P700755_RS06435
uniprot id: K4ICI5
names: Similarity
messages: Belongs to the UPF0145 family.

313595:P700755 RS08295
gene id: 313595:P700755_RS08295
uniprot id: K4IT41
names: Similarity
messages: Belongs to the UPF0102 family.

313595:P700755 RS17725
gene id: 313595:P700755_RS17725
uniprot id: K4IJD1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

313595:P700755 RS12470
gene id: 313595:P700755_RS12470
uniprot id: K4IFZ2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS04565
gene id: 313595:P700755_RS04565
uniprot id: K4IC04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

313595:P700755 RS02775
gene id: 313595:P700755_RS02775
uniprot id: K4IQ51
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

313595:P700755 RS01840
gene id: 313595:P700755_RS01840
uniprot id: K4IPI4
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

313595:P700755 RS17700
gene id: 313595:P700755_RS17700
uniprot id: K4IJC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxC family.
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

313595:P700755 RS08500
gene id: 313595:P700755_RS08500
uniprot id: K4IDL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS12485
gene id: 313595:P700755_RS12485
uniprot id: K4IVG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

313595:P700755 RS02310
gene id: 313595:P700755_RS02310
uniprot id: K4IAB0
names: Similarity
messages: Belongs to the threonine aldolase family.

313595:P700755 RS06970
gene id: 313595:P700755_RS06970
uniprot id: K4IH57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

313595:P700755 RS06780
gene id: 313595:P700755_RS06780
uniprot id: Q1VPB1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

313595:P700755 RS15245
gene id: 313595:P700755_RS15245
uniprot id: K4IX26
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

313595:P700755 RS17565
gene id: 313595:P700755_RS17565
uniprot id: K4IIN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS10675
gene id: 313595:P700755_RS10675
uniprot id: K4IUG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

313595:P700755 RS01625
gene id: 313595:P700755_RS01625
uniprot id: K4IBV2
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

313595:P700755 RS05935
gene id: 313595:P700755_RS05935
uniprot id: K4ICT1
names: Similarity
messages: Belongs to the peptidase S41A family.

313595:P700755 RS00215
gene id: 313595:P700755_RS00215
uniprot id: K4IDE2
names: Similarity
messages: Belongs to the asparagine synthetase family.

313595:P700755 RS07500
gene id: 313595:P700755_RS07500
uniprot id: K4ISS8
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

313595:P700755 RS10150
gene id: 313595:P700755_RS10150
uniprot id: K4IEP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04440
gene id: 313595:P700755_RS04440
uniprot id: K4IDH8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

313595:P700755 RS10605
gene id: 313595:P700755_RS10605
uniprot id: K4IJ19
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

313595:P700755 RS16835
gene id: 313595:P700755_RS16835
uniprot id: K4IIU0
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS05715
gene id: 313595:P700755_RS05715
uniprot id: K4IC39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kinesin light chain family.
messages: cytoskeleton

313595:P700755 RS01300
gene id: 313595:P700755_RS01300
uniprot id: K4IBN0
names: Similarity
messages: Belongs to the AlaDH/PNT family.

313595:P700755 RS05665
gene id: 313595:P700755_RS05665
uniprot id: K4IGH4
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

313595:P700755 RS09470
gene id: 313595:P700755_RS09470
uniprot id: K4ITQ1
names: Similarity
messages: Belongs to the pyruvate kinase family.

313595:P700755 RS07115
gene id: 313595:P700755_RS07115
uniprot id: K4ISH9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

313595:P700755 RS09115
gene id: 313595:P700755_RS09115
uniprot id: K4IEG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

313595:P700755 RS10530
gene id: 313595:P700755_RS10530
uniprot id: K4IJ06
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

313595:P700755 RS15960
gene id: 313595:P700755_RS15960
uniprot id: K4IHW2
names: Similarity
messages: Belongs to the SusD family.

313595:P700755 RS15660
gene id: 313595:P700755_RS15660
uniprot id: K4IX88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

313595:P700755 RS13975
gene id: 313595:P700755_RS13975
uniprot id: K4IW95
names: Cofactor
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.

313595:P700755 RS13100
gene id: 313595:P700755_RS13100
uniprot id: K4IGE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS10105
gene id: 313595:P700755_RS10105
uniprot id: K4IGV2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS13180
gene id: 313595:P700755_RS13180
uniprot id: K4IKH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

313595:P700755 RS05070
gene id: 313595:P700755_RS05070
uniprot id: K4IRH1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS00300
gene id: 313595:P700755_RS00300
uniprot id: K4IB59
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS08170
gene id: 313595:P700755_RS08170
uniprot id: K4IE01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS14975
gene id: 313595:P700755_RS14975
uniprot id: Q1VPB1
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

313595:P700755 RS13790
gene id: 313595:P700755_RS13790
uniprot id: K4IH66
names: Similarity
messages: Belongs to the universal stress protein A family.

313595:P700755 RS04855
gene id: 313595:P700755_RS04855
uniprot id: K4IBP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

313595:P700755 RS00730
gene id: 313595:P700755_RS00730
uniprot id: K4INU9
names: Similarity
messages: Belongs to the ice-binding protein family.

313595:P700755 RS17740
gene id: 313595:P700755_RS17740
uniprot id: K4IIR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS12540
gene id: 313595:P700755_RS12540
uniprot id: K4IG09
names: Similarity
messages: Belongs to the peptidase S51 family.

313595:P700755 RS06975
gene id: 313595:P700755_RS06975
uniprot id: K4ICU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

313595:P700755 RS14900
gene id: 313595:P700755_RS14900
uniprot id: K4IHA9
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS11060
gene id: 313595:P700755_RS11060
uniprot id: K4IF60
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS04645
gene id: 313595:P700755_RS04645
uniprot id: K4IFY6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

313595:P700755 RS15795
gene id: 313595:P700755_RS15795
uniprot id: K4IHT6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS01195
gene id: 313595:P700755_RS01195
uniprot id: K4I9J8
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05200
gene id: 313595:P700755_RS05200
uniprot id: K4IG90
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

313595:P700755 RS09120
gene id: 313595:P700755_RS09120
uniprot id: K4ITI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

313595:P700755 RS00295
gene id: 313595:P700755_RS00295
uniprot id: K4I941
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

313595:P700755 RS00500
gene id: 313595:P700755_RS00500
uniprot id: K4IDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

313595:P700755 RS11515
gene id: 313595:P700755_RS11515
uniprot id: K4IHI1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

313595:P700755 RS00805
gene id: 313595:P700755_RS00805
uniprot id: K4IDN3
names: Similarity
messages: Belongs to the UPF0246 family.

313595:P700755 RS01735
gene id: 313595:P700755_RS01735
uniprot id: K4IPF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

313595:P700755 RS08240
gene id: 313595:P700755_RS08240
uniprot id: K4IE10
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS02205
gene id: 313595:P700755_RS02205
uniprot id: K4IPU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

313595:P700755 RS00670
gene id: 313595:P700755_RS00670
uniprot id: K4IDL5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15225
gene id: 313595:P700755_RS15225
uniprot id: K4ILQ4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

313595:P700755 RS13230
gene id: 313595:P700755_RS13230
uniprot id: K4IGX2
names: Similarity
messages: Belongs to the AIR synthase family.

313595:P700755 RS14500
gene id: 313595:P700755_RS14500
uniprot id: K4IH35
names: Similarity
messages: Belongs to the HSP15 family.

313595:P700755 RS10170
gene id: 313595:P700755_RS10170
uniprot id: K4IIU6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

313595:P700755 RS02990
gene id: 313595:P700755_RS02990
uniprot id: K4IQ96
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

313595:P700755 RS07785
gene id: 313595:P700755_RS07785
uniprot id: K4ISW6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

313595:P700755 RS11445
gene id: 313595:P700755_RS11445
uniprot id: K4IHG8
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

313595:P700755 RS08630
gene id: 313595:P700755_RS08630
uniprot id: K4IT95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

313595:P700755 RS02300
gene id: 313595:P700755_RS02300
uniprot id: K4IPW1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313595:P700755 RS17055
gene id: 313595:P700755_RS17055
uniprot id: K4IID6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS17770
gene id: 313595:P700755_RS17770
uniprot id: K4IKZ6
names: Similarity
messages: Belongs to the CarB family.

313595:P700755 RS07640
gene id: 313595:P700755_RS07640
uniprot id: K4IHK1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS05880
gene id: 313595:P700755_RS05880
uniprot id: K4IED2
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

313595:P700755 RS16990
gene id: 313595:P700755_RS16990
uniprot id: K4IKH5
names: Similarity
messages: Belongs to the DEAD box helicase family.

313595:P700755 RS02025
gene id: 313595:P700755_RS02025
uniprot id: K4IC41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS04160
gene id: 313595:P700755_RS04160
uniprot id: K4IBQ6
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313595:P700755 RS08640
gene id: 313595:P700755_RS08640
uniprot id: K4IDP0
names: Similarity
messages: Belongs to the LacAB/RpiB family.

313595:P700755 RS06320
gene id: 313595:P700755_RS06320
uniprot id: K4ICG0
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

313595:P700755 RS14925
gene id: 313595:P700755_RS14925
uniprot id: K4ILH2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS14790
gene id: 313595:P700755_RS14790
uniprot id: K4IWQ2
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS08180
gene id: 313595:P700755_RS08180
uniprot id: K4IHT7
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

313595:P700755 RS17625
gene id: 313595:P700755_RS17625
uniprot id: K4IJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

313595:P700755 RS08360
gene id: 313595:P700755_RS08360
uniprot id: K4IFS2
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

313595:P700755 RS09610
gene id: 313595:P700755_RS09610
uniprot id: K4IGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.
messages: Cell membrane

313595:P700755 RS12465
gene id: 313595:P700755_RS12465
uniprot id: K4IVF5
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

313595:P700755 RS17280
gene id: 313595:P700755_RS17280
uniprot id: K4IMS8
names: Similarity
messages: Belongs to the peptidase M13 family.

313595:P700755 RS00400
gene id: 313595:P700755_RS00400
uniprot id: K4IB80
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS14115
gene id: 313595:P700755_RS14115
uniprot id: K4IIV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell inner membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

313595:P700755 RS03065
gene id: 313595:P700755_RS03065
uniprot id: K4IF09
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

313595:P700755 RS02245
gene id: 313595:P700755_RS02245
uniprot id: K4IAS2
names: Similarity
messages: Belongs to the SUI1 family.

313595:P700755 RS14625
gene id: 313595:P700755_RS14625
uniprot id: K4IH52
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313595:P700755 RS02975
gene id: 313595:P700755_RS02975
uniprot id: K4IAM1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS03285
gene id: 313595:P700755_RS03285
uniprot id: K4IQE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS14700
gene id: 313595:P700755_RS14700
uniprot id: K4IH64
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

313595:P700755 RS01145
gene id: 313595:P700755_RS01145
uniprot id: K4IDV1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313595:P700755 RS10610
gene id: 313595:P700755_RS10610
uniprot id: K4IEX6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

313595:P700755 RS01320
gene id: 313595:P700755_RS01320
uniprot id: K4I9M9
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated Cas9 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.
messages: Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.
messages: Monomer. Binds crRNA and tracrRNA.

313595:P700755 RS09220
gene id: 313595:P700755_RS09220
uniprot id: K4IG69
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS14325
gene id: 313595:P700755_RS14325
uniprot id: K4IHG1
names: Similarity
messages: Belongs to the NAD synthetase family.

313595:P700755 RS15100
gene id: 313595:P700755_RS15100
uniprot id: K4IHE4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

313595:P700755 RS10075
gene id: 313595:P700755_RS10075
uniprot id: K4IEN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS13325
gene id: 313595:P700755_RS13325
uniprot id: K4IGZ0
names: Cofactor
names: Similarity
messages: Belongs to the DNA photolyase family.
messages: Binds 1 FAD per subunit.

313595:P700755 RS09190
gene id: 313595:P700755_RS09190
uniprot id: K4IG64
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

313595:P700755 RS11615
gene id: 313595:P700755_RS11615
uniprot id: K4IFX3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

313595:P700755 RS05885
gene id: 313595:P700755_RS05885
uniprot id: K4ICS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS07200
gene id: 313595:P700755_RS07200
uniprot id: K4ICY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS14525
gene id: 313595:P700755_RS14525
uniprot id: K4IH41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS01225
gene id: 313595:P700755_RS01225
uniprot id: K4IBL7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS00540
gene id: 313595:P700755_RS00540
uniprot id: K4I9T5
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

313595:P700755 RS12085
gene id: 313595:P700755_RS12085
uniprot id: K4IG77
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

313595:P700755 RS04225
gene id: 313595:P700755_RS04225
uniprot id: K4IBA6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05975
gene id: 313595:P700755_RS05975
uniprot id: K4IC83
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS16845
gene id: 313595:P700755_RS16845
uniprot id: K4IMI4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS16830
gene id: 313595:P700755_RS16830
uniprot id: K4IKE0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

313595:P700755 RS04215
gene id: 313595:P700755_RS04215
uniprot id: K4IQX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

313595:P700755 RS12440
gene id: 313595:P700755_RS12440
uniprot id: K4IVE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313595:P700755 RS04835
gene id: 313595:P700755_RS04835
uniprot id: K4IC79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

313595:P700755 RS04695
gene id: 313595:P700755_RS04695
uniprot id: K4IG07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

313595:P700755 RS07695
gene id: 313595:P700755_RS07695
uniprot id: K4IDA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS08570
gene id: 313595:P700755_RS08570
uniprot id: K4IE68
names: Similarity
messages: Belongs to the Nudix hydrolase family.

313595:P700755 RS08665
gene id: 313595:P700755_RS08665
uniprot id: K4IDP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS05130
gene id: 313595:P700755_RS05130
uniprot id: K4IBU2
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

313595:P700755 RS11310
gene id: 313595:P700755_RS11310
uniprot id: K4IFS5
names: Similarity
messages: Belongs to the aspartokinase family.

313595:P700755 RS04725
gene id: 313595:P700755_RS04725
uniprot id: K4IBM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

313595:P700755 RS14320
gene id: 313595:P700755_RS14320
uniprot id: K4IIZ7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

313595:P700755 RS04140
gene id: 313595:P700755_RS04140
uniprot id: K4IQV6
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

313595:P700755 RS09055
gene id: 313595:P700755_RS09055
uniprot id: K4IDX1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

313595:P700755 RS08380
gene id: 313595:P700755_RS08380
uniprot id: K4IDK0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS01020
gene id: 313595:P700755_RS01020
uniprot id: K4IA23
names: Similarity
messages: Belongs to the PspA/IM30 family.

313595:P700755 RS13205
gene id: 313595:P700755_RS13205
uniprot id: K4IGW8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS05080
gene id: 313595:P700755_RS05080
uniprot id: K4IBT2
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS07055
gene id: 313595:P700755_RS07055
uniprot id: K4ICV6
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

313595:P700755 RS14555
gene id: 313595:P700755_RS14555
uniprot id: K4IJ49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS09150
gene id: 313595:P700755_RS09150
uniprot id: K4II87
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10030
gene id: 313595:P700755_RS10030
uniprot id: K4IGU1
names: Similarity
messages: Belongs to the SCO1/2 family.

313595:P700755 RS00240
gene id: 313595:P700755_RS00240
uniprot id: K4IDE7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

313595:P700755 RS05255
gene id: 313595:P700755_RS05255
uniprot id: K4IBW4
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS11635
gene id: 313595:P700755_RS11635
uniprot id: K4IJJ8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

313595:P700755 RS06235
gene id: 313595:P700755_RS06235
uniprot id: K4IS29
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

313595:P700755 RS03605
gene id: 313595:P700755_RS03605
uniprot id: K4IQK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS18365
gene id: 313595:P700755_RS18365
uniprot id: K4IYN2
names: Subcellular Location Annotation
messages: Cytoplasm

313595:P700755 RS17130
gene id: 313595:P700755_RS17130
uniprot id: K4IKK2
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09605
gene id: 313595:P700755_RS09605
uniprot id: K4IEA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

313595:P700755 RS14345
gene id: 313595:P700755_RS14345
uniprot id: K4IJ03
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

313595:P700755 RS16380
gene id: 313595:P700755_RS16380
uniprot id: K4IIM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

313595:P700755 RS13810
gene id: 313595:P700755_RS13810
uniprot id: K4IGQ5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09585
gene id: 313595:P700755_RS09585
uniprot id: K4IGG1
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

313595:P700755 RS04560
gene id: 313595:P700755_RS04560
uniprot id: K4IDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

313595:P700755 RS17125
gene id: 313595:P700755_RS17125
uniprot id: K4IIE6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS13415
gene id: 313595:P700755_RS13415
uniprot id: K4IGJ9
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS04390
gene id: 313595:P700755_RS04390
uniprot id: K4IBW0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

313595:P700755 RS02645
gene id: 313595:P700755_RS02645
uniprot id: K4IAZ6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS05925
gene id: 313595:P700755_RS05925
uniprot id: K4IC76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

313595:P700755 RS07735
gene id: 313595:P700755_RS07735
uniprot id: K4ISW0
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

313595:P700755 RS14425
gene id: 313595:P700755_RS14425
uniprot id: K4IHI0
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

313595:P700755 RS05185
gene id: 313595:P700755_RS05185
uniprot id: K4IE09
names: Similarity
messages: Belongs to the SufE family.

313595:P700755 RS15855
gene id: 313595:P700755_RS15855
uniprot id: K4IIE1
names: Similarity
messages: Belongs to the SusD family.

313595:P700755 RS02265
gene id: 313595:P700755_RS02265
uniprot id: K4ICB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

313595:P700755 RS14210
gene id: 313595:P700755_RS14210
uniprot id: K4IGX9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

313595:P700755 RS02970
gene id: 313595:P700755_RS02970
uniprot id: K4IEZ9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

313595:P700755 RS05825
gene id: 313595:P700755_RS05825
uniprot id: K4IC57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

313595:P700755 RS11480
gene id: 313595:P700755_RS11480
uniprot id: K4IJH8
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS03870
gene id: 313595:P700755_RS03870
uniprot id: K4IQR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

313595:P700755 RS01785
gene id: 313595:P700755_RS01785
uniprot id: K4IPH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

313595:P700755 RS07765
gene id: 313595:P700755_RS07765
uniprot id: K4IHM3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

313595:P700755 RS04555
gene id: 313595:P700755_RS04555
uniprot id: K4IBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Membrane

313595:P700755 RS15490
gene id: 313595:P700755_RS15490
uniprot id: K4IX61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

313595:P700755 RS01850
gene id: 313595:P700755_RS01850
uniprot id: K4I9Z0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09615
gene id: 313595:P700755_RS09615
uniprot id: K4IEP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

313595:P700755 RS10365
gene id: 313595:P700755_RS10365
uniprot id: K4IGZ6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS04745
gene id: 313595:P700755_RS04745
uniprot id: K4IG17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

313595:P700755 RS01870
gene id: 313595:P700755_RS01870
uniprot id: K4IEC0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS13260
gene id: 313595:P700755_RS13260
uniprot id: K4IVX2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.
messages: Binds 1 FAD per subunit.
messages: May have a photoreceptor function.

313595:P700755 RS03705
gene id: 313595:P700755_RS03705
uniprot id: K4IB00
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

313595:P700755 RS11230
gene id: 313595:P700755_RS11230
uniprot id: K4IHD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

313595:P700755 RS05445
gene id: 313595:P700755_RS05445
uniprot id: K4IGD5
names: Similarity
messages: Belongs to the peptidase M16 family.

313595:P700755 RS14770
gene id: 313595:P700755_RS14770
uniprot id: K4ILD5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS15965
gene id: 313595:P700755_RS15965
uniprot id: K4IJY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS08325
gene id: 313595:P700755_RS08325
uniprot id: K4IHV9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

313595:P700755 RS03970
gene id: 313595:P700755_RS03970
uniprot id: K4IQS2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

313595:P700755 RS04690
gene id: 313595:P700755_RS04690
uniprot id: K4IRA9
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

313595:P700755 RS07150
gene id: 313595:P700755_RS07150
uniprot id: K4ICX9
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

313595:P700755 RS10565
gene id: 313595:P700755_RS10565
uniprot id: K4IH27
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

313595:P700755 RS04165
gene id: 313595:P700755_RS04165
uniprot id: K4IQW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

313595:P700755 RS06655
gene id: 313595:P700755_RS06655
uniprot id: K4ID56
names: Similarity
messages: Belongs to the histone deacetylase family.

313595:P700755 RS00320
gene id: 313595:P700755_RS00320
uniprot id: K4I945
names: Similarity
messages: Belongs to the threonine synthase family.

313595:P700755 RS10495
gene id: 313595:P700755_RS10495
uniprot id: K4IFA7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05205
gene id: 313595:P700755_RS05205
uniprot id: K4IBV5
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

313595:P700755 RS00565
gene id: 313595:P700755_RS00565
uniprot id: K4I9U1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS00260
gene id: 313595:P700755_RS00260
uniprot id: K4INK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

313595:P700755 RS09490
gene id: 313595:P700755_RS09490
uniprot id: K4IEM2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

313595:P700755 RS07715
gene id: 313595:P700755_RS07715
uniprot id: K4IHL5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

313595:P700755 RS04700
gene id: 313595:P700755_RS04700
uniprot id: K4IBM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

313595:P700755 RS01755
gene id: 313595:P700755_RS01755
uniprot id: K4IAF5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.

313595:P700755 RS00450
gene id: 313595:P700755_RS00450
uniprot id: K4IB89
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS00420
gene id: 313595:P700755_RS00420
uniprot id: K4I964
names: Caution
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS16685
gene id: 313595:P700755_RS16685
uniprot id: K4IIR9
names: Similarity
messages: Belongs to the P(II) protein family.

313595:P700755 RS13145
gene id: 313595:P700755_RS13145
uniprot id: K4IGW0
names: Similarity
messages: Belongs to the DapA family.

313595:P700755 RS08950
gene id: 313595:P700755_RS08950
uniprot id: K4IDU8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04530
gene id: 313595:P700755_RS04530
uniprot id: K4IBH1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

313595:P700755 RS09550
gene id: 313595:P700755_RS09550
uniprot id: K4IIG9
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16445
gene id: 313595:P700755_RS16445
uniprot id: K4II28
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane
messages: Mn(2+), Zn(2+), Cd(2+) and Co(2+) support activity to lesser extents.

313595:P700755 RS04715
gene id: 313595:P700755_RS04715
uniprot id: K4IRB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

313595:P700755 RS03765
gene id: 313595:P700755_RS03765
uniprot id: K4IBJ4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

313595:P700755 RS05160
gene id: 313595:P700755_RS05160
uniprot id: K4IE03
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the trehalose phosphatase family.

313595:P700755 RS02445
gene id: 313595:P700755_RS02445
uniprot id: K4IAV7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

313595:P700755 RS09440
gene id: 313595:P700755_RS09440
uniprot id: K4IEL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrC family.
messages: Cytoplasm
messages: Interacts with UvrB in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.

313595:P700755 RS14040
gene id: 313595:P700755_RS14040
uniprot id: K4IIU2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

313595:P700755 RS17445
gene id: 313595:P700755_RS17445
uniprot id: K4IKS0
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

313595:P700755 RS12545
gene id: 313595:P700755_RS12545
uniprot id: K4II22
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS11760
gene id: 313595:P700755_RS11760
uniprot id: K4IFK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS16815
gene id: 313595:P700755_RS16815
uniprot id: K4IXS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

313595:P700755 RS13750
gene id: 313595:P700755_RS13750
uniprot id: K4IKS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

313595:P700755 RS10355
gene id: 313595:P700755_RS10355
uniprot id: K4IIX5
names: Similarity
messages: Belongs to the HMG-CoA reductase family.

313595:P700755 RS14870
gene id: 313595:P700755_RS14870
uniprot id: K4ILG0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10020
gene id: 313595:P700755_RS10020
uniprot id: K4IIS7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15175
gene id: 313595:P700755_RS15175
uniprot id: K4II33
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

313595:P700755 RS09020
gene id: 313595:P700755_RS09020
uniprot id: K4II60
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

313595:P700755 RS06980
gene id: 313595:P700755_RS06980
uniprot id: K4IEY5
names: Similarity
messages: Belongs to the ribF family.

313595:P700755 RS14090
gene id: 313595:P700755_RS14090
uniprot id: K4IIV1
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

313595:P700755 RS07510
gene id: 313595:P700755_RS07510
uniprot id: K4ID74
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

313595:P700755 RS16425
gene id: 313595:P700755_RS16425
uniprot id: K4IK67
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

313595:P700755 RS01155
gene id: 313595:P700755_RS01155
uniprot id: K4I9I7
names: Similarity
messages: Belongs to the HicA mRNA interferase family.

313595:P700755 RS16920
gene id: 313595:P700755_RS16920
uniprot id: K4IXU2
names: Similarity
messages: Belongs to the DNA polymerase type-Y family.

313595:P700755 RS05030
gene id: 313595:P700755_RS05030
uniprot id: K4IBS4
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

313595:P700755 RS13190
gene id: 313595:P700755_RS13190
uniprot id: K4IIF8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

313595:P700755 RS10540
gene id: 313595:P700755_RS10540
uniprot id: K4IH23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

313595:P700755 RS02555
gene id: 313595:P700755_RS02555
uniprot id: K4IER8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313595:P700755 RS11585
gene id: 313595:P700755_RS11585
uniprot id: K4IFH0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

313595:P700755 RS04600
gene id: 313595:P700755_RS04600
uniprot id: K4IFV6
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

313595:P700755 RS16010
gene id: 313595:P700755_RS16010
uniprot id: K4IHX0
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

313595:P700755 RS14520
gene id: 313595:P700755_RS14520
uniprot id: K4IL79
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

313595:P700755 RS03550
gene id: 313595:P700755_RS03550
uniprot id: K4IF96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS13165
gene id: 313595:P700755_RS13165
uniprot id: K4IIF5
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

313595:P700755 RS07760
gene id: 313595:P700755_RS07760
uniprot id: K4ISW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

313595:P700755 RS10650
gene id: 313595:P700755_RS10650
uniprot id: K4IUF9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313595:P700755 RS00180
gene id: 313595:P700755_RS00180
uniprot id: K4I9L8
names: Similarity
messages: Belongs to the DEAD box helicase family.

313595:P700755 RS17950
gene id: 313595:P700755_RS17950
uniprot id: K4IYG8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

313595:P700755 RS03530
gene id: 313595:P700755_RS03530
uniprot id: K4IAW8
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

313595:P700755 RS02810
gene id: 313595:P700755_RS02810
uniprot id: K4IAI8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BPG-independent phosphoglycerate mutase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Monomer.

313595:P700755 RS13135
gene id: 313595:P700755_RS13135
uniprot id: K4IGF2
names: Similarity
messages: Belongs to the proline racemase family.

313595:P700755 RS12700
gene id: 313595:P700755_RS12700
uniprot id: K4IVN0
names: Function
names: Similarity
messages: Belongs to the acyltransferase CrtO family.
messages: Catalyzes the acylation of glycosyl-4,4'-diaponeurosporenoate, i.e. the esterification of glucose at the C6'' position with the carboxyl group of the C(15) fatty acid 12-methyltetradecanoic acid, to yield staphyloxanthin. This is the last step in the biosynthesis of this orange pigment, present in most staphylococci strains.

313595:P700755 RS11380
gene id: 313595:P700755_RS11380
uniprot id: K4IHG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

313595:P700755 RS15090
gene id: 313595:P700755_RS15090
uniprot id: K4IWX8
names: Similarity
messages: To endonucleases of group I introns of fungi and phage.

313595:P700755 RS09540
gene id: 313595:P700755_RS09540
uniprot id: K4IEN1
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09625
gene id: 313595:P700755_RS09625
uniprot id: K4III3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

313595:P700755 RS15525
gene id: 313595:P700755_RS15525
uniprot id: K4IJR3
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

313595:P700755 RS10340
gene id: 313595:P700755_RS10340
uniprot id: K4IGZ2
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16370
gene id: 313595:P700755_RS16370
uniprot id: K4II19
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

313595:P700755 RS13280
gene id: 313595:P700755_RS13280
uniprot id: K4IVX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

313595:P700755 RS02305
gene id: 313595:P700755_RS02305
uniprot id: K4IEM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 3B subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

313595:P700755 RS02085
gene id: 313595:P700755_RS02085
uniprot id: K4IEJ5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

313595:P700755 RS06275
gene id: 313595:P700755_RS06275
uniprot id: K4IEK2
names: Function
names: Similarity
messages: Belongs to the HMBS family.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.

313595:P700755 RS10600
gene id: 313595:P700755_RS10600
uniprot id: K4IUF0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

313595:P700755 RS04665
gene id: 313595:P700755_RS04665
uniprot id: K4IRA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

313595:P700755 RS00865
gene id: 313595:P700755_RS00865
uniprot id: K4IBF8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS13170
gene id: 313595:P700755_RS13170
uniprot id: K4IGW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS00175
gene id: 313595:P700755_RS00175
uniprot id: K4IB36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Membrane

313595:P700755 RS08660
gene id: 313595:P700755_RS08660
uniprot id: K4II08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

313595:P700755 RS02660
gene id: 313595:P700755_RS02660
uniprot id: K4IAF9
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

313595:P700755 RS16825
gene id: 313595:P700755_RS16825
uniprot id: K4II90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein bS6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein bS6.

313595:P700755 RS16325
gene id: 313595:P700755_RS16325
uniprot id: K4IK53
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

313595:P700755 RS11170
gene id: 313595:P700755_RS11170
uniprot id: K4IJC6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

313595:P700755 RS12020
gene id: 313595:P700755_RS12020
uniprot id: K4IV61
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

313595:P700755 RS12810
gene id: 313595:P700755_RS12810
uniprot id: K4IGR0
names: Subunit
messages: Homodimer.

313595:P700755 RS01955
gene id: 313595:P700755_RS01955
uniprot id: K4IC25
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

313595:P700755 RS14060
gene id: 313595:P700755_RS14060
uniprot id: K4IGU8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

313595:P700755 RS02465
gene id: 313595:P700755_RS02465
uniprot id: K4ICF7
names: Function
names: Similarity
messages: Belongs to the RNase Y family.
messages: Endoribonuclease that initiates mRNA decay.

313595:P700755 RS02045
gene id: 313595:P700755_RS02045
uniprot id: K4IC69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XseA family.
messages: Cytoplasm

313595:P700755 RS05590
gene id: 313595:P700755_RS05590
uniprot id: K4ICK9
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00370
gene id: 313595:P700755_RS00370
uniprot id: K4I956
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS01920
gene id: 313595:P700755_RS01920
uniprot id: K4IED1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

313595:P700755 RS14785
gene id: 313595:P700755_RS14785
uniprot id: K4IHQ6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS12585
gene id: 313595:P700755_RS12585
uniprot id: K4IK76
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

313595:P700755 RS17675
gene id: 313595:P700755_RS17675
uniprot id: K4IJC0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

313595:P700755 RS11220
gene id: 313595:P700755_RS11220
uniprot id: K4IJD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

313595:P700755 RS12705
gene id: 313595:P700755_RS12705
uniprot id: K4IK86
names: Similarity
messages: Belongs to the peptidase S33 family.

313595:P700755 RS11260
gene id: 313595:P700755_RS11260
uniprot id: K4IFR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS17690
gene id: 313595:P700755_RS17690
uniprot id: K4IIR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

313595:P700755 RS09465
gene id: 313595:P700755_RS09465
uniprot id: K4IEL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

313595:P700755 RS05920
gene id: 313595:P700755_RS05920
uniprot id: K4IGL8
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

313595:P700755 RS00365
gene id: 313595:P700755_RS00365
uniprot id: K4IDG6
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00485
gene id: 313595:P700755_RS00485
uniprot id: K4IB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

313595:P700755 RS05930
gene id: 313595:P700755_RS05930
uniprot id: K4IEE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

313595:P700755 RS01910
gene id: 313595:P700755_RS01910
uniprot id: K4IAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

313595:P700755 RS00325
gene id: 313595:P700755_RS00325
uniprot id: K4IB64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS10195
gene id: 313595:P700755_RS10195
uniprot id: K4IIV0
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

313595:P700755 RS00490
gene id: 313595:P700755_RS00490
uniprot id: K4I9S6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

313595:P700755 RS07190
gene id: 313595:P700755_RS07190
uniprot id: K4ISJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS02330
gene id: 313595:P700755_RS02330
uniprot id: K4IEN2
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

313595:P700755 RS08790
gene id: 313595:P700755_RS08790
uniprot id: K4IEA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of glycine to tRNA(Gly).
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS04620
gene id: 313595:P700755_RS04620
uniprot id: K4IR62
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

313595:P700755 RS10125
gene id: 313595:P700755_RS10125
uniprot id: K4IEP2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

313595:P700755 RS17880
gene id: 313595:P700755_RS17880
uniprot id: K4IN96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

313595:P700755 RS06750
gene id: 313595:P700755_RS06750
uniprot id: K4ISB3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS03475
gene id: 313595:P700755_RS03475
uniprot id: K4IF81
names: Function
names: Similarity
messages: Belongs to the PemK/MazF family.
messages: Toxic component of a type II toxin-antitoxin (TA) system.

313595:P700755 RS00780
gene id: 313595:P700755_RS00780
uniprot id: K4IDM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAPS reductase family. CysH subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
messages: Cytoplasm

313595:P700755 RS15475
gene id: 313595:P700755_RS15475
uniprot id: K4IHN4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

313595:P700755 RS12120
gene id: 313595:P700755_RS12120
uniprot id: K4IFS9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

313595:P700755 RS09570
gene id: 313595:P700755_RS09570
uniprot id: K4ITS4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

313595:P700755 RS07770
gene id: 313595:P700755_RS07770
uniprot id: K4IDB2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

313595:P700755 RS15220
gene id: 313595:P700755_RS15220
uniprot id: K4IX24
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

313595:P700755 RS00495
gene id: 313595:P700755_RS00495
uniprot id: K4INQ1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

313595:P700755 RS05150
gene id: 313595:P700755_RS05150
uniprot id: K4IG80
names: Cofactor
names: PTM
names: Subcellular Location Annotation
messages: Binds 2 heme groups per subunit.
messages: Binds 2 heme groups.
messages: Periplasm

313595:P700755 RS08290
gene id: 313595:P700755_RS08290
uniprot id: K4IE19
names: Similarity
messages: Belongs to the peptidase S66 family.

313595:P700755 RS00375
gene id: 313595:P700755_RS00375
uniprot id: K4IB74
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

313595:P700755 RS07075
gene id: 313595:P700755_RS07075
uniprot id: K4IH77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

313595:P700755 RS15805
gene id: 313595:P700755_RS15805
uniprot id: K4IID3
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

313595:P700755 RS00820
gene id: 313595:P700755_RS00820
uniprot id: K4I9Y5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00680
gene id: 313595:P700755_RS00680
uniprot id: K4IBD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS00580
gene id: 313595:P700755_RS00580
uniprot id: K4IBB2
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS11975
gene id: 313595:P700755_RS11975
uniprot id: K4IJS4
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS08985
gene id: 313595:P700755_RS08985
uniprot id: K4IED7
names: Similarity
messages: Belongs to the GARS family.

313595:P700755 RS02655
gene id: 313595:P700755_RS02655
uniprot id: K4IET7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

313595:P700755 RS10430
gene id: 313595:P700755_RS10430
uniprot id: K4IIY9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS15145
gene id: 313595:P700755_RS15145
uniprot id: K4IHF2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

313595:P700755 RS10805
gene id: 313595:P700755_RS10805
uniprot id: K4IJ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS16545
gene id: 313595:P700755_RS16545
uniprot id: K4IK83
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS13805
gene id: 313595:P700755_RS13805
uniprot id: K4IKT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell inner membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

313595:P700755 RS17470
gene id: 313595:P700755_RS17470
uniprot id: K4IKS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313595:P700755 RS12200
gene id: 313595:P700755_RS12200
uniprot id: K4IFU5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15735
gene id: 313595:P700755_RS15735
uniprot id: K4IXA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell inner membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

313595:P700755 RS14845
gene id: 313595:P700755_RS14845
uniprot id: K4ILF3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS09060
gene id: 313595:P700755_RS09060
uniprot id: K4IG37
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

313595:P700755 RS08345
gene id: 313595:P700755_RS08345
uniprot id: K4IT50
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS02735
gene id: 313595:P700755_RS02735
uniprot id: K4IAH3
names: Similarity
messages: Belongs to the peptidase S51 family.

313595:P700755 RS09430
gene id: 313595:P700755_RS09430
uniprot id: K4IE59
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

313595:P700755 RS10145
gene id: 313595:P700755_RS10145
uniprot id: K4IIU3
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05260
gene id: 313595:P700755_RS05260
uniprot id: K4IE24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

313595:P700755 RS15680
gene id: 313595:P700755_RS15680
uniprot id: K4IIB2
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

313595:P700755 RS11835
gene id: 313595:P700755_RS11835
uniprot id: K4IHN6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

313595:P700755 RS15540
gene id: 313595:P700755_RS15540
uniprot id: K4II89
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313595:P700755 RS03995
gene id: 313595:P700755_RS03995
uniprot id: K4IQS8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS00690
gene id: 313595:P700755_RS00690
uniprot id: K4INU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

313595:P700755 RS09040
gene id: 313595:P700755_RS09040
uniprot id: K4IEE8
names: Subunit
messages: Homodimer.

313595:P700755 RS14030
gene id: 313595:P700755_RS14030
uniprot id: K4IKX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

313595:P700755 RS14375
gene id: 313595:P700755_RS14375
uniprot id: K4IHH0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS17080
gene id: 313595:P700755_RS17080
uniprot id: K4IIE3
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09330
gene id: 313595:P700755_RS09330
uniprot id: K4IE36
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

313595:P700755 RS04680
gene id: 313595:P700755_RS04680
uniprot id: K4IDR4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

313595:P700755 RS07955
gene id: 313595:P700755_RS07955
uniprot id: K4IFK5
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

313595:P700755 RS09155
gene id: 313595:P700755_RS09155
uniprot id: K4IDZ5
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS12075
gene id: 313595:P700755_RS12075
uniprot id: K4IFS0
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

313595:P700755 RS06155
gene id: 313595:P700755_RS06155
uniprot id: K4ICX4
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

313595:P700755 RS20625
gene id: 313595:P700755_RS20625
uniprot id: K4IDA2
names: Similarity
messages: Belongs to the ice-binding protein family.

313595:P700755 RS18795
gene id: 313595:P700755_RS18795
uniprot id: K4IVA4
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS02925
gene id: 313595:P700755_RS02925
uniprot id: K4IAL3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

313595:P700755 RS13840
gene id: 313595:P700755_RS13840
uniprot id: K4IKT8
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

313595:P700755 RS15290
gene id: 313595:P700755_RS15290
uniprot id: K4II52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS11270
gene id: 313595:P700755_RS11270
uniprot id: K4IJE6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

313595:P700755 RS07100
gene id: 313595:P700755_RS07100
uniprot id: K4IH82
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS07195
gene id: 313595:P700755_RS07195
uniprot id: K4IHA3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

313595:P700755 RS02570
gene id: 313595:P700755_RS02570
uniprot id: K4IAY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

313595:P700755 RS06105
gene id: 313595:P700755_RS06105
uniprot id: K4ICW2
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

313595:P700755 RS17835
gene id: 313595:P700755_RS17835
uniprot id: K4IIW6
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

313595:P700755 RS02600
gene id: 313595:P700755_RS02600
uniprot id: K4IQ14
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

313595:P700755 RS16390
gene id: 313595:P700755_RS16390
uniprot id: K4IMA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS07930
gene id: 313595:P700755_RS07930
uniprot id: K4IFK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SbcD family.
messages: Heterodimer of SbcC and SbcD.
messages: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.

313595:P700755 RS12430
gene id: 313595:P700755_RS12430
uniprot id: K4II01
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell inner membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313595:P700755 RS11875
gene id: 313595:P700755_RS11875
uniprot id: K4IJQ1
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

313595:P700755 RS10625
gene id: 313595:P700755_RS10625
uniprot id: K4IUF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

313595:P700755 RS09170
gene id: 313595:P700755_RS09170
uniprot id: K4ITJ4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04900
gene id: 313595:P700755_RS04900
uniprot id: K4IG39
names: Cofactor
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Probably binds two magnesium or manganese ions per subunit.

313595:P700755 RS16365
gene id: 313595:P700755_RS16365
uniprot id: K4IM97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

313595:P700755 RS12815
gene id: 313595:P700755_RS12815
uniprot id: K4IVP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS15980
gene id: 313595:P700755_RS15980
uniprot id: K4IM35
names: Cofactor
messages: Binds 2 magnesium ions per subunit.

313595:P700755 RS04605
gene id: 313595:P700755_RS04605
uniprot id: K4IBI6
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

313595:P700755 RS08555
gene id: 313595:P700755_RS08555
uniprot id: K4IDM6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

313595:P700755 RS02835
gene id: 313595:P700755_RS02835
uniprot id: K4IAJ2
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

313595:P700755 RS03050
gene id: 313595:P700755_RS03050
uniprot id: K4ICS4
names: Cofactor
messages: Binds 1 zinc ion per subunit.

313595:P700755 RS06160
gene id: 313595:P700755_RS06160
uniprot id: K4IS14
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

313595:P700755 RS13435
gene id: 313595:P700755_RS13435
uniprot id: K4IKM2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS18830
gene id: 313595:P700755_RS18830
uniprot id: K4IKQ3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313595:P700755 RS04760
gene id: 313595:P700755_RS04760
uniprot id: K4IC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS12960
gene id: 313595:P700755_RS12960
uniprot id: K4IGT2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS11525
gene id: 313595:P700755_RS11525
uniprot id: K4IUX3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

313595:P700755 RS05215
gene id: 313595:P700755_RS05215
uniprot id: K4ICE1
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

313595:P700755 RS00055
gene id: 313595:P700755_RS00055
uniprot id: K4I9J4
names: Function
names: Similarity
messages: Belongs to the transposase 11 family.
messages: Involved in the transposition of the insertion sequence IS5.

313595:P700755 RS04820
gene id: 313595:P700755_RS04820
uniprot id: K4IG28
names: Similarity
messages: Belongs to the UPF0758 family.

313595:P700755 RS16875
gene id: 313595:P700755_RS16875
uniprot id: K4IMI9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

313595:P700755 RS14545
gene id: 313595:P700755_RS14545
uniprot id: K4IL85
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS01610
gene id: 313595:P700755_RS01610
uniprot id: K4IPD7
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.

313595:P700755 RS03060
gene id: 313595:P700755_RS03060
uniprot id: K4IQA4
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

313595:P700755 RS01110
gene id: 313595:P700755_RS01110
uniprot id: K4IDU5
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

313595:P700755 RS05115
gene id: 313595:P700755_RS05115
uniprot id: K4ICC1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS00605
gene id: 313595:P700755_RS00605
uniprot id: K4IBB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

313595:P700755 RS14440
gene id: 313595:P700755_RS14440
uniprot id: K4IH25
names: Function
names: Similarity
messages: Belongs to the Thz kinase family.
messages: Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

313595:P700755 RS18855
gene id: 313595:P700755_RS18855
uniprot id: K4IWP1
names: Similarity
messages: Belongs to the peptidase S8 family.

313595:P700755 RS09130
gene id: 313595:P700755_RS09130
uniprot id: K4IDZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

313595:P700755 RS09825
gene id: 313595:P700755_RS09825
uniprot id: K4ITX1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

313595:P700755 RS17750
gene id: 313595:P700755_RS17750
uniprot id: K4IJD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS12395
gene id: 313595:P700755_RS12395
uniprot id: K4IK14
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS14865
gene id: 313595:P700755_RS14865
uniprot id: K4IWS2
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

313595:P700755 RS00945
gene id: 313595:P700755_RS00945
uniprot id: K4IBH3
names: Similarity
messages: Belongs to the malate synthase family.

313595:P700755 RS02470
gene id: 313595:P700755_RS02470
uniprot id: K4IAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

313595:P700755 RS09110
gene id: 313595:P700755_RS09110
uniprot id: K4IG48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: Cell inner membrane
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

313595:P700755 RS08300
gene id: 313595:P700755_RS08300
uniprot id: K4IHV5
names: Similarity
messages: Belongs to the pirin family.

313595:P700755 RS00545
gene id: 313595:P700755_RS00545
uniprot id: K4INR0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS02630
gene id: 313595:P700755_RS02630
uniprot id: K4IET2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

313595:P700755 RS03165
gene id: 313595:P700755_RS03165
uniprot id: K4ICU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YajC family.
messages: Membrane

313595:P700755 RS02450
gene id: 313595:P700755_RS02450
uniprot id: K4IPY6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

313595:P700755 RS15250
gene id: 313595:P700755_RS15250
uniprot id: K4ILQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS10015
gene id: 313595:P700755_RS10015
uniprot id: K4IU50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

313595:P700755 RS10010
gene id: 313595:P700755_RS10010
uniprot id: K4IF27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS15380
gene id: 313595:P700755_RS15380
uniprot id: K4ILT0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS04615
gene id: 313595:P700755_RS04615
uniprot id: K4IC17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

313595:P700755 RS17630
gene id: 313595:P700755_RS17630
uniprot id: K4IY76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

313595:P700755 RS05845
gene id: 313595:P700755_RS05845
uniprot id: K4IGK5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313595:P700755 RS16905
gene id: 313595:P700755_RS16905
uniprot id: K4IIA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS02705
gene id: 313595:P700755_RS02705
uniprot id: K4IEU7
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

313595:P700755 RS14035
gene id: 313595:P700755_RS14035
uniprot id: K4IGU4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

313595:P700755 RS16695
gene id: 313595:P700755_RS16695
uniprot id: K4IMF6
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

313595:P700755 RS07020
gene id: 313595:P700755_RS07020
uniprot id: K4ISF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

313595:P700755 RS14150
gene id: 313595:P700755_RS14150
uniprot id: K4IWC7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

313595:P700755 RS02375
gene id: 313595:P700755_RS02375
uniprot id: K4IPX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

313595:P700755 RS16005
gene id: 313595:P700755_RS16005
uniprot id: K4IM40
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS15300
gene id: 313595:P700755_RS15300
uniprot id: K4ILR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS05510
gene id: 313595:P700755_RS05510
uniprot id: K4IRP1
names: Similarity
messages: Belongs to the peptidase S8 family.

313595:P700755 RS09485
gene id: 313595:P700755_RS09485
uniprot id: K4IGD6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

313595:P700755 RS14205
gene id: 313595:P700755_RS14205
uniprot id: K4IL15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cleaves the N-terminal amino acid of tripeptides.
messages: Cytoplasm

313595:P700755 RS01290
gene id: 313595:P700755_RS01290
uniprot id: K4IDY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS17955
gene id: 313595:P700755_RS17955
uniprot id: K4INA9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

313595:P700755 RS11235
gene id: 313595:P700755_RS11235
uniprot id: K4IFQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

313595:P700755 RS05050
gene id: 313595:P700755_RS05050
uniprot id: K4IG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS16630
gene id: 313595:P700755_RS16630
uniprot id: K4IIR4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

313595:P700755 RS00235
gene id: 313595:P700755_RS00235
uniprot id: K4INK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

313595:P700755 RS06140
gene id: 313595:P700755_RS06140
uniprot id: K4IGR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm

313595:P700755 RS05055
gene id: 313595:P700755_RS05055
uniprot id: K4IBS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS03860
gene id: 313595:P700755_RS03860
uniprot id: K4ID64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

313595:P700755 RS08245
gene id: 313595:P700755_RS08245
uniprot id: K4IT34
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS14640
gene id: 313595:P700755_RS14640
uniprot id: K4IWL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

313595:P700755 RS07165
gene id: 313595:P700755_RS07165
uniprot id: K4ISJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS15265
gene id: 313595:P700755_RS15265
uniprot id: K4II48
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS09405
gene id: 313595:P700755_RS09405
uniprot id: K4IE53
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the peroxidase family. Peroxidase/catalase subfamily.
messages: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.
messages: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS09575
gene id: 313595:P700755_RS09575
uniprot id: K4IIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

313595:P700755 RS14400
gene id: 313595:P700755_RS14400
uniprot id: K4IHH5
names: Subcellular Location Annotation
messages: Cytoplasm

313595:P700755 RS15630
gene id: 313595:P700755_RS15630
uniprot id: K4IJS6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NnrD/CARKD family.
messages: Belongs to the NnrE/AIBP family.
messages: Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the NnrD/CARKD family.
messages: In the N-terminal section; belongs to the NnrE/AIBP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS12655
gene id: 313595:P700755_RS12655
uniprot id: K4II65
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS06315
gene id: 313595:P700755_RS06315
uniprot id: K4IGU2
names: Similarity
messages: Belongs to the peptidase S41A family.

313595:P700755 RS04765
gene id: 313595:P700755_RS04765
uniprot id: K4IRC0
names: Similarity
messages: Belongs to the SusD family.

313595:P700755 RS16925
gene id: 313595:P700755_RS16925
uniprot id: K4IMK0
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

313595:P700755 RS06985
gene id: 313595:P700755_RS06985
uniprot id: K4IDC0
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00570
gene id: 313595:P700755_RS00570
uniprot id: K4IDJ8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS12115
gene id: 313595:P700755_RS12115
uniprot id: K4IJV8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

313595:P700755 RS15800
gene id: 313595:P700755_RS15800
uniprot id: K4IJW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

313595:P700755 RS14550
gene id: 313595:P700755_RS14550
uniprot id: K4IH45
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

313595:P700755 RS17925
gene id: 313595:P700755_RS17925
uniprot id: K4IYG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

313595:P700755 RS10615
gene id: 313595:P700755_RS10615
uniprot id: K4IH36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

313595:P700755 RS16290
gene id: 313595:P700755_RS16290
uniprot id: K4IM85
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS08130
gene id: 313595:P700755_RS08130
uniprot id: K4IHS9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.

313595:P700755 RS10185
gene id: 313595:P700755_RS10185
uniprot id: K4IF61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Required for cell division and gliding motility.

313595:P700755 RS11680
gene id: 313595:P700755_RS11680
uniprot id: K4IUZ5
names: Similarity
messages: Belongs to the fabD family.

313595:P700755 RS12410
gene id: 313595:P700755_RS12410
uniprot id: K4IGF4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313595:P700755 RS15760
gene id: 313595:P700755_RS15760
uniprot id: K4IXA6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

313595:P700755 RS02080
gene id: 313595:P700755_RS02080
uniprot id: K4IPS3
names: Similarity
messages: Belongs to the CvfB family.

313595:P700755 RS20330
gene id: 313595:P700755_RS20330
uniprot id: K4IJ00
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313595:P700755 RS14225
gene id: 313595:P700755_RS14225
uniprot id: K4IWE2
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

313595:P700755 RS10580
gene id: 313595:P700755_RS10580
uniprot id: K4IJ15
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

313595:P700755 RS09500
gene id: 313595:P700755_RS09500
uniprot id: K4IIF6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

313595:P700755 RS07655
gene id: 313595:P700755_RS07655
uniprot id: K4IDR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS11715
gene id: 313595:P700755_RS11715
uniprot id: K4IFJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

313595:P700755 RS04685
gene id: 313595:P700755_RS04685
uniprot id: K4IC54
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

313595:P700755 RS13320
gene id: 313595:P700755_RS13320
uniprot id: K4IIH9
names: Cofactor
messages: Binds 1 FAD per subunit.

313595:P700755 RS02530
gene id: 313595:P700755_RS02530
uniprot id: K4IER3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

313595:P700755 RS09630
gene id: 313595:P700755_RS09630
uniprot id: K4IEA6
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

313595:P700755 RS03245
gene id: 313595:P700755_RS03245
uniprot id: K4IBA4
names: Subcellular Location Annotation
messages: Cytoplasm

313595:P700755 RS05265
gene id: 313595:P700755_RS05265
uniprot id: K4ICF1
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

313595:P700755 RS14020
gene id: 313595:P700755_RS14020
uniprot id: K4IHB3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS03670
gene id: 313595:P700755_RS03670
uniprot id: K4IFB8
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

313595:P700755 RS07425
gene id: 313595:P700755_RS07425
uniprot id: K4ID60
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

313595:P700755 RS16385
gene id: 313595:P700755_RS16385
uniprot id: K4IXK5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

313595:P700755 RS04115
gene id: 313595:P700755_RS04115
uniprot id: K4IQV1
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

313595:P700755 RS02615
gene id: 313595:P700755_RS02615
uniprot id: K4ICI7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS01725
gene id: 313595:P700755_RS01725
uniprot id: K4IBX1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

313595:P700755 RS17635
gene id: 313595:P700755_RS17635
uniprot id: K4IN06
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

313595:P700755 RS04985
gene id: 313595:P700755_RS04985
uniprot id: K4IDX0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

313595:P700755 RS16220
gene id: 313595:P700755_RS16220
uniprot id: K4IHZ9
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

313595:P700755 RS01065
gene id: 313595:P700755_RS01065
uniprot id: K4IDT4
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS02685
gene id: 313595:P700755_RS02685
uniprot id: K4IAG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

313595:P700755 RS15585
gene id: 313595:P700755_RS15585
uniprot id: K4IX76
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS05600
gene id: 313595:P700755_RS05600
uniprot id: K4IGF8
names: Similarity
messages: Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.

313595:P700755 RS14725
gene id: 313595:P700755_RS14725
uniprot id: K4IJ82
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS09875
gene id: 313595:P700755_RS09875
uniprot id: K4ITY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

313595:P700755 RS09030
gene id: 313595:P700755_RS09030
uniprot id: K4IG32
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

313595:P700755 RS03155
gene id: 313595:P700755_RS03155
uniprot id: K4IF24
names: Similarity
messages: Belongs to the thioredoxin family.

313595:P700755 RS15830
gene id: 313595:P700755_RS15830
uniprot id: K4IID8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

313595:P700755 RS14535
gene id: 313595:P700755_RS14535
uniprot id: K4IHK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell inner membrane

313595:P700755 RS00555
gene id: 313595:P700755_RS00555
uniprot id: K4I984
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

313595:P700755 RS17945
gene id: 313595:P700755_RS17945
uniprot id: K4IJJ7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

313595:P700755 RS11510
gene id: 313595:P700755_RS11510
uniprot id: K4IFF3
names: Function
names: Subunit
messages: Heterodimer of an alpha and a beta chain.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

313595:P700755 RS17140
gene id: 313595:P700755_RS17140
uniprot id: K4IMP8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS15215
gene id: 313595:P700755_RS15215
uniprot id: K4II41
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL31 family.

313595:P700755 RS06545
gene id: 313595:P700755_RS06545
uniprot id: K4ID34
names: Function
messages: Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.

313595:P700755 RS12710
gene id: 313595:P700755_RS12710
uniprot id: K4IG79
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS15340
gene id: 313595:P700755_RS15340
uniprot id: K4IJN0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

313595:P700755 RS15590
gene id: 313595:P700755_RS15590
uniprot id: K4ILW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS12145
gene id: 313595:P700755_RS12145
uniprot id: K4IFT5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IcmF family.
messages: Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
messages: Homodimer.
messages: Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS12065
gene id: 313595:P700755_RS12065
uniprot id: K4IV72
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

313595:P700755 RS17575
gene id: 313595:P700755_RS17575
uniprot id: K4IJ96
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

313595:P700755 RS00810
gene id: 313595:P700755_RS00810
uniprot id: K4I9C0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

313595:P700755 RS15435
gene id: 313595:P700755_RS15435
uniprot id: K4II73
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15635
gene id: 313595:P700755_RS15635
uniprot id: K4IIA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAL/histidase family.
messages: Cytoplasm

313595:P700755 RS05835
gene id: 313595:P700755_RS05835
uniprot id: K4ICR1
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

313595:P700755 RS07065
gene id: 313595:P700755_RS07065
uniprot id: K4IDD8
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

313595:P700755 RS02035
gene id: 313595:P700755_RS02035
uniprot id: K4IEI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

313595:P700755 RS11730
gene id: 313595:P700755_RS11730
uniprot id: K4IV04
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS02845
gene id: 313595:P700755_RS02845
uniprot id: K4IB32
names: Similarity
messages: Belongs to the sterol desaturase family.

313595:P700755 RS06125
gene id: 313595:P700755_RS06125
uniprot id: K4IEH8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

313595:P700755 RS16450
gene id: 313595:P700755_RS16450
uniprot id: K4IK72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

313595:P700755 RS16690
gene id: 313595:P700755_RS16690
uniprot id: K4IXP8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

313595:P700755 RS07725
gene id: 313595:P700755_RS07725
uniprot id: K4IFG4
names: Similarity
messages: Belongs to the Skp family.

313595:P700755 RS17025
gene id: 313595:P700755_RS17025
uniprot id: K4IMM5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS01635
gene id: 313595:P700755_RS01635
uniprot id: K4IPE1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

313595:P700755 RS14315
gene id: 313595:P700755_RS14315
uniprot id: K4IGZ8
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

313595:P700755 RS15690
gene id: 313595:P700755_RS15690
uniprot id: K4ILY3
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS02355
gene id: 313595:P700755_RS02355
uniprot id: K4IEN4
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

313595:P700755 RS11840
gene id: 313595:P700755_RS11840
uniprot id: K4IG19
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

313595:P700755 RS09945
gene id: 313595:P700755_RS09945
uniprot id: K4IEX5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvB family.
messages: Cytoplasm
messages: Has 3 domains, the large (RuvB-L) and small ATPase (RuvB-S) domains and the C-terminal head (RuvB-H) domain. The head domain binds DNA, while the ATPase domains jointly bind ATP, ADP or are empty depending on the state of the subunit in the translocation cycle. During a single DNA translocation step the structure of each domain remains the same, but their relative positions change.
messages: Homohexamer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.

313595:P700755 RS09940
gene id: 313595:P700755_RS09940
uniprot id: K4IGN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

313595:P700755 RS09525
gene id: 313595:P700755_RS09525
uniprot id: K4IIG3
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS14010
gene id: 313595:P700755_RS14010
uniprot id: K4IGT9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS05230
gene id: 313595:P700755_RS05230
uniprot id: K4IBW1
names: Similarity
messages: Belongs to the DprA/Smf family.

313595:P700755 RS00895
gene id: 313595:P700755_RS00895
uniprot id: K4I9Z9
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

313595:P700755 RS09340
gene id: 313595:P700755_RS09340
uniprot id: K4IEJ7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

313595:P700755 RS16810
gene id: 313595:P700755_RS16810
uniprot id: K4IIT7
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.

313595:P700755 RS17650
gene id: 313595:P700755_RS17650
uniprot id: K4IJB4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

313595:P700755 RS04640
gene id: 313595:P700755_RS04640
uniprot id: K4IR87
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

313595:P700755 RS05860
gene id: 313595:P700755_RS05860
uniprot id: K4ICR6
names: Similarity
messages: Belongs to the UPF0045 family.

313595:P700755 RS02730
gene id: 313595:P700755_RS02730
uniprot id: K4IEV1
names: Similarity
names: Subunit
messages: Belongs to the glutaminase family.
messages: Homotetramer.

313595:P700755 RS06220
gene id: 313595:P700755_RS06220
uniprot id: K4ICD5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

313595:P700755 RS02285
gene id: 313595:P700755_RS02285
uniprot id: K4IAA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS04635
gene id: 313595:P700755_RS04635
uniprot id: K4IC45
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

313595:P700755 RS08695
gene id: 313595:P700755_RS08695
uniprot id: K4IFX2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

313595:P700755 RS15710
gene id: 313595:P700755_RS15710
uniprot id: K4IX96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

313595:P700755 RS11930
gene id: 313595:P700755_RS11930
uniprot id: K4IFN7
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

313595:P700755 RS15510
gene id: 313595:P700755_RS15510
uniprot id: K4II85
names: Similarity
messages: Belongs to the nitroreductase family.

313595:P700755 RS10005
gene id: 313595:P700755_RS10005
uniprot id: K4IGS9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell inner membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

313595:P700755 RS08250
gene id: 313595:P700755_RS08250
uniprot id: K4IHU6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS17065
gene id: 313595:P700755_RS17065
uniprot id: K4IIY7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05865
gene id: 313595:P700755_RS05865
uniprot id: K4IRV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane

313595:P700755 RS06270
gene id: 313595:P700755_RS06270
uniprot id: K4ICE7
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

313595:P700755 RS09175
gene id: 313595:P700755_RS09175
uniprot id: K4II91
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

313595:P700755 RS01040
gene id: 313595:P700755_RS01040
uniprot id: K4IBJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS03015
gene id: 313595:P700755_RS03015
uniprot id: K4IF03
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS01765
gene id: 313595:P700755_RS01765
uniprot id: K4IE97
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

313595:P700755 RS00795
gene id: 313595:P700755_RS00795
uniprot id: K4I9Y0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

313595:P700755 RS16870
gene id: 313595:P700755_RS16870
uniprot id: K4IXT3
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

313595:P700755 RS06020
gene id: 313595:P700755_RS06020
uniprot id: K4IGN5
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS14380
gene id: 313595:P700755_RS14380
uniprot id: K4IWH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane
messages: Membrane

313595:P700755 RS07705
gene id: 313595:P700755_RS07705
uniprot id: K4IDS5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS10745
gene id: 313595:P700755_RS10745
uniprot id: K4IUH8
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10660
gene id: 313595:P700755_RS10660
uniprot id: K4IEY6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

313595:P700755 RS12420
gene id: 313595:P700755_RS12420
uniprot id: K4IK22
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

313595:P700755 RS04705
gene id: 313595:P700755_RS04705
uniprot id: K4IDS0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

313595:P700755 RS14390
gene id: 313595:P700755_RS14390
uniprot id: K4IH15
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS00075
gene id: 313595:P700755_RS00075
uniprot id: K4I9J9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

313595:P700755 RS14890
gene id: 313595:P700755_RS14890
uniprot id: K4ILG6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

313595:P700755 RS13445
gene id: 313595:P700755_RS13445
uniprot id: K4IIK2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

313595:P700755 RS10100
gene id: 313595:P700755_RS10100
uniprot id: K4IEN7
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS17760
gene id: 313595:P700755_RS17760
uniprot id: K4IN37
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

313595:P700755 RS13075
gene id: 313595:P700755_RS13075
uniprot id: K4IIE0
names: Similarity
messages: Belongs to the peptidase M1 family.

313595:P700755 RS06565
gene id: 313595:P700755_RS06565
uniprot id: K4IEP8
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

313595:P700755 RS14510
gene id: 313595:P700755_RS14510
uniprot id: K4IHJ5
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

313595:P700755 RS04860
gene id: 313595:P700755_RS04860
uniprot id: K4IDU9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS03290
gene id: 313595:P700755_RS03290
uniprot id: K4IF49
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

313595:P700755 RS10410
gene id: 313595:P700755_RS10410
uniprot id: K4IET8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

313595:P700755 RS14825
gene id: 313595:P700755_RS14825
uniprot id: K4IH92
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

313595:P700755 RS08420
gene id: 313595:P700755_RS08420
uniprot id: K4IT64
names: Similarity
messages: Belongs to the peptidase M13 family.

313595:P700755 RS13220
gene id: 313595:P700755_RS13220
uniprot id: K4IGG7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS16615
gene id: 313595:P700755_RS16615
uniprot id: K4IME2
names: Similarity
messages: Belongs to the Dps family.

313595:P700755 RS13920
gene id: 313595:P700755_RS13920
uniprot id: K4IKV4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

313595:P700755 RS07070
gene id: 313595:P700755_RS07070
uniprot id: K4ISG7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

313595:P700755 RS11300
gene id: 313595:P700755_RS11300
uniprot id: K4IFA9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS16340
gene id: 313595:P700755_RS16340
uniprot id: K4IM93
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

313595:P700755 RS00645
gene id: 313595:P700755_RS00645
uniprot id: K4IDL1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

313595:P700755 RS10190
gene id: 313595:P700755_RS10190
uniprot id: K4IU83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS07255
gene id: 313595:P700755_RS07255
uniprot id: K4ICZ7
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

313595:P700755 RS03760
gene id: 313595:P700755_RS03760
uniprot id: K4ID41
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

313595:P700755 RS10925
gene id: 313595:P700755_RS10925
uniprot id: K4IH84
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

313595:P700755 RS14195
gene id: 313595:P700755_RS14195
uniprot id: K4IHE3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

313595:P700755 RS09980
gene id: 313595:P700755_RS09980
uniprot id: K4IIQ8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

313595:P700755 RS18560
gene id: 313595:P700755_RS18560
uniprot id: K4I9F2
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

313595:P700755 RS07750
gene id: 313595:P700755_RS07750
uniprot id: K4IFG8
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

313595:P700755 RS11710
gene id: 313595:P700755_RS11710
uniprot id: K4IJL6
names: Similarity
messages: Belongs to the TrpF family.

313595:P700755 RS09965
gene id: 313595:P700755_RS09965
uniprot id: K4IGP3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

313595:P700755 RS05100
gene id: 313595:P700755_RS05100
uniprot id: K4IG72
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS11815
gene id: 313595:P700755_RS11815
uniprot id: K4IG14
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

313595:P700755 RS10575
gene id: 313595:P700755_RS10575
uniprot id: K4IUE6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

313595:P700755 RS16660
gene id: 313595:P700755_RS16660
uniprot id: K4IIR6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

313595:P700755 RS01275
gene id: 313595:P700755_RS01275
uniprot id: K4IBM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

313595:P700755 RS04650
gene id: 313595:P700755_RS04650
uniprot id: K4IBL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

313595:P700755 RS06150
gene id: 313595:P700755_RS06150
uniprot id: K4IEI2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

313595:P700755 RS09970
gene id: 313595:P700755_RS09970
uniprot id: K4IEY0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RuvA family.
messages: Cytoplasm
messages: Has three domains with a flexible linker between the domains II and III and assumes an 'L' shape. Domain III is highly mobile and contacts RuvB.
messages: Homotetramer. Forms an RuvA(8)-RuvB(12)-Holliday junction (HJ) complex. HJ DNA is sandwiched between 2 RuvA tetramers; dsDNA enters through RuvA and exits via RuvB. An RuvB hexamer assembles on each DNA strand where it exits the tetramer. Each RuvB hexamer is contacted by two RuvA subunits (via domain III) on 2 adjacent RuvB subunits; this complex drives branch migration. In the full resolvosome a probable DNA-RuvA(4)-RuvB(12)-RuvC(2) complex forms which resolves the HJ.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.

313595:P700755 RS11055
gene id: 313595:P700755_RS11055
uniprot id: K4IJA2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

313595:P700755 RS17655
gene id: 313595:P700755_RS17655
uniprot id: K4IY83
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

313595:P700755 RS04740
gene id: 313595:P700755_RS04740
uniprot id: K4IRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

313595:P700755 RS13225
gene id: 313595:P700755_RS13225
uniprot id: K4IIG2
names: Similarity
messages: Belongs to the glutamine synthetase family.

313595:P700755 RS04655
gene id: 313595:P700755_RS04655
uniprot id: K4IDP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

313595:P700755 RS01035
gene id: 313595:P700755_RS01035
uniprot id: K4I9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0719 family.
messages: Membrane

313595:P700755 RS08960
gene id: 313595:P700755_RS08960
uniprot id: K4IED4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

313595:P700755 RS14130
gene id: 313595:P700755_RS14130
uniprot id: K4IL01
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

313595:P700755 RS18460
gene id: 313595:P700755_RS18460
uniprot id: K4INJ3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS09450
gene id: 313595:P700755_RS09450
uniprot id: K4IIE8
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

313595:P700755 RS17195
gene id: 313595:P700755_RS17195
uniprot id: K4IMQ9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

313595:P700755 RS00230
gene id: 313595:P700755_RS00230
uniprot id: K4I9M7
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

313595:P700755 RS02680
gene id: 313595:P700755_RS02680
uniprot id: K4IEU2
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

313595:P700755 RS15905
gene id: 313595:P700755_RS15905
uniprot id: K4IHV3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

313595:P700755 RS17075
gene id: 313595:P700755_RS17075
uniprot id: K4IMN7
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS10490
gene id: 313595:P700755_RS10490
uniprot id: K4IH16
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

313595:P700755 RS01595
gene id: 313595:P700755_RS01595
uniprot id: K4I9U0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS15325
gene id: 313595:P700755_RS15325
uniprot id: K4IX36
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

313595:P700755 RS10685
gene id: 313595:P700755_RS10685
uniprot id: K4IEY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS04670
gene id: 313595:P700755_RS04670
uniprot id: K4IG02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

313595:P700755 RS09125
gene id: 313595:P700755_RS09125
uniprot id: K4II80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

313595:P700755 RS11965
gene id: 313595:P700755_RS11965
uniprot id: K4IG47
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

313595:P700755 RS03810
gene id: 313595:P700755_RS03810
uniprot id: K4ID53
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

313595:P700755 RS13315
gene id: 313595:P700755_RS13315
uniprot id: K4IGI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

313595:P700755 RS15685
gene id: 313595:P700755_RS15685
uniprot id: K4IX93
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS15235
gene id: 313595:P700755_RS15235
uniprot id: K4IJL2
names: Subcellular Location Annotation
messages: Membrane

313595:P700755 RS05895
gene id: 313595:P700755_RS05895
uniprot id: K4IGL3
names: Similarity
messages: Belongs to the DNase I family.

313595:P700755 RS09065
gene id: 313595:P700755_RS09065
uniprot id: K4IEF2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

313595:P700755 RS03725
gene id: 313595:P700755_RS03725
uniprot id: K4IFC9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

313595:P700755 RS12080
gene id: 313595:P700755_RS12080
uniprot id: K4IHT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

313595:P700755 RS10755
gene id: 313595:P700755_RS10755
uniprot id: K4IF02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

313595:P700755 RS13910
gene id: 313595:P700755_RS13910
uniprot id: K4IH88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Mitochondrion

313595:P700755 RS13820
gene id: 313595:P700755_RS13820
uniprot id: K4IH70
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

313595:P700755 RS12490
gene id: 313595:P700755_RS12490
uniprot id: K4IK39
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M38 family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two zinc ions.
messages: Carboxylation allows a single lysine to coordinate two zinc ions.
messages: Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
messages: Cytoplasm

313595:P700755 RS06210
gene id: 313595:P700755_RS06210
uniprot id: K4IS25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

313595:P700755 RS09950
gene id: 313595:P700755_RS09950
uniprot id: K4IU01
names: Similarity
messages: Belongs to the cytochrome P450 family.

313595:P700755 RS13385
gene id: 313595:P700755_RS13385
uniprot id: K4IKL3
names: Similarity
messages: Belongs to the universal stress protein A family.

313595:P700755 RS05095
gene id: 313595:P700755_RS05095
uniprot id: K4IRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

313595:P700755 RS16820
gene id: 313595:P700755_RS16820
uniprot id: K4IMH8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

313595:P700755 RS08340
gene id: 313595:P700755_RS08340
uniprot id: K4IE27
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

313595:P700755 RS05910
gene id: 313595:P700755_RS05910
uniprot id: K4ICS7
names: Similarity
messages: Belongs to the SusD family.

313595:P700755 RS05250
gene id: 313595:P700755_RS05250
uniprot id: K4IGA0
names: Cofactor
messages: Binds 1 zinc ion per subunit.

313595:P700755 RS02340
gene id: 313595:P700755_RS02340
uniprot id: K4ICD3
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

313595:P700755 RS10520
gene id: 313595:P700755_RS10520
uniprot id: K4IFB2
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

313595:P700755 RS16020
gene id: 313595:P700755_RS16020
uniprot id: K4IIG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

313595:P700755 RS09880
gene id: 313595:P700755_RS09880
uniprot id: K4IIN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

313595:P700755 RS15985
gene id: 313595:P700755_RS15985
uniprot id: K4IHW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 65 family.

313595:P700755 RS14120
gene id: 313595:P700755_RS14120
uniprot id: K4IHD2
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

313595:P700755 RS02825
gene id: 313595:P700755_RS02825
uniprot id: K4IQ61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

313595:P700755 RS09215
gene id: 313595:P700755_RS09215
uniprot id: K4IE07
names: Similarity
messages: Belongs to the peptidase S9A family.