309803:CTN RS03955
gene id: 309803:CTN_RS03955
uniprot id: B9K7P6
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02995
gene id: 309803:CTN_RS02995
uniprot id: B9K741
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

309803:CTN RS00020
gene id: 309803:CTN_RS00020
uniprot id: B9KAY4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

309803:CTN RS09495
gene id: 309803:CTN_RS09495
uniprot id: B9KAV0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

309803:CTN RS07050
gene id: 309803:CTN_RS07050
uniprot id: B9K9F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309803:CTN RS01140
gene id: 309803:CTN_RS01140
uniprot id: B9KBL2
names: Function
names: Similarity
messages: Belongs to the UxaE family.
messages: Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA).

309803:CTN RS02390
gene id: 309803:CTN_RS02390
uniprot id: B9K6S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DisA family.
messages: Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
messages: Homooctamer.
messages: Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.

309803:CTN RS00710
gene id: 309803:CTN_RS00710
uniprot id: B9KBC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

309803:CTN RS04745
gene id: 309803:CTN_RS04745
uniprot id: B9K854
names: Similarity
messages: Belongs to the asp23 family.

309803:CTN RS00675
gene id: 309803:CTN_RS00675
uniprot id: B9KBC2
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

309803:CTN RS07410
gene id: 309803:CTN_RS07410
uniprot id: B9K9M5
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS07335
gene id: 309803:CTN_RS07335
uniprot id: B9K9K8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

309803:CTN RS02815
gene id: 309803:CTN_RS02815
uniprot id: B9K702
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS05005
gene id: 309803:CTN_RS05005
uniprot id: B9K8A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

309803:CTN RS06830
gene id: 309803:CTN_RS06830
uniprot id: B9K9A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
messages: Cell membrane
messages: Membrane

309803:CTN RS04960
gene id: 309803:CTN_RS04960
uniprot id: B9K896
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

309803:CTN RS01400
gene id: 309803:CTN_RS01400
uniprot id: B9KBR3
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

309803:CTN RS04615
gene id: 309803:CTN_RS04615
uniprot id: B9K829
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06810
gene id: 309803:CTN_RS06810
uniprot id: B9K9A4
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02780
gene id: 309803:CTN_RS02780
uniprot id: B9K6Z5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

309803:CTN RS01700
gene id: 309803:CTN_RS01700
uniprot id: B9KBX4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

309803:CTN RS04705
gene id: 309803:CTN_RS04705
uniprot id: B9K846
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

309803:CTN RS04325
gene id: 309803:CTN_RS04325
uniprot id: B9K7W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

309803:CTN RS04905
gene id: 309803:CTN_RS04905
uniprot id: B9K885
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

309803:CTN RS01065
gene id: 309803:CTN_RS01065
uniprot id: B9KBK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.

309803:CTN RS08850
gene id: 309803:CTN_RS08850
uniprot id: B9KAG7
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

309803:CTN RS04760
gene id: 309803:CTN_RS04760
uniprot id: B9K857
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

309803:CTN RS01950
gene id: 309803:CTN_RS01950
uniprot id: B9KC26
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06700
gene id: 309803:CTN_RS06700
uniprot id: B9K982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS06780
gene id: 309803:CTN_RS06780
uniprot id: B9K998
names: Similarity
messages: Belongs to the complex I 49 kDa subunit family.

309803:CTN RS05775
gene id: 309803:CTN_RS05775
uniprot id: B9K8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell inner membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

309803:CTN RS00305
gene id: 309803:CTN_RS00305
uniprot id: B9KB46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS03070
gene id: 309803:CTN_RS03070
uniprot id: B9K756
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

309803:CTN RS01390
gene id: 309803:CTN_RS01390
uniprot id: B9KBR1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

309803:CTN RS08415
gene id: 309803:CTN_RS08415
uniprot id: B9KA80
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

309803:CTN RS02160
gene id: 309803:CTN_RS02160
uniprot id: B9K6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309803:CTN RS07300
gene id: 309803:CTN_RS07300
uniprot id: B9K9K1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309803:CTN RS07810
gene id: 309803:CTN_RS07810
uniprot id: B9K9V6
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

309803:CTN RS07520
gene id: 309803:CTN_RS07520
uniprot id: B9K9P8
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

309803:CTN RS07720
gene id: 309803:CTN_RS07720
uniprot id: B9K9T9
names: Similarity
messages: Belongs to the UxaA family.

309803:CTN RS03910
gene id: 309803:CTN_RS03910
uniprot id: B9K7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

309803:CTN RS06230
gene id: 309803:CTN_RS06230
uniprot id: B9K8Z0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

309803:CTN RS01440
gene id: 309803:CTN_RS01440
uniprot id: B9KBS2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AP endonuclease 2 family.
messages: Binds 3 Zn(2+) ions.
messages: Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.

309803:CTN RS08515
gene id: 309803:CTN_RS08515
uniprot id: B9KA99
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

309803:CTN RS02655
gene id: 309803:CTN_RS02655
uniprot id: B9K6W9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

309803:CTN RS09175
gene id: 309803:CTN_RS09175
uniprot id: B9KAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

309803:CTN RS02250
gene id: 309803:CTN_RS02250
uniprot id: B9K6Q1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

309803:CTN RS03060
gene id: 309803:CTN_RS03060
uniprot id: B9K754
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

309803:CTN RS00605
gene id: 309803:CTN_RS00605
uniprot id: B9KBA8
names: Similarity
messages: Belongs to the class-I fumarase family.

309803:CTN RS05015
gene id: 309803:CTN_RS05015
uniprot id: B9K8A7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.
messages: Cytoplasm
messages: Monomer.

309803:CTN RS08600
gene id: 309803:CTN_RS08600
uniprot id: B9KAB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

309803:CTN RS04925
gene id: 309803:CTN_RS04925
uniprot id: B9K889
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

309803:CTN RS04535
gene id: 309803:CTN_RS04535
uniprot id: B9K812
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

309803:CTN RS05275
gene id: 309803:CTN_RS05275
uniprot id: B9K8F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

309803:CTN RS03975
gene id: 309803:CTN_RS03975
uniprot id: B9K7Q0
names: Similarity
messages: Belongs to the UPF0047 family.

309803:CTN RS07635
gene id: 309803:CTN_RS07635
uniprot id: B9K9S1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

309803:CTN RS00520
gene id: 309803:CTN_RS00520
uniprot id: B9KB91
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

309803:CTN RS08755
gene id: 309803:CTN_RS08755
uniprot id: B9KAE8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309803:CTN RS04945
gene id: 309803:CTN_RS04945
uniprot id: B9K893
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

309803:CTN RS06145
gene id: 309803:CTN_RS06145
uniprot id: B9K8X3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

309803:CTN RS08460
gene id: 309803:CTN_RS08460
uniprot id: B9KA89
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309803:CTN RS08645
gene id: 309803:CTN_RS08645
uniprot id: B9KAC4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

309803:CTN RS00390
gene id: 309803:CTN_RS00390
uniprot id: B9KB64
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell inner membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

309803:CTN RS01060
gene id: 309803:CTN_RS01060
uniprot id: B9KBK0
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

309803:CTN RS05350
gene id: 309803:CTN_RS05350
uniprot id: B9K8H2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

309803:CTN RS04865
gene id: 309803:CTN_RS04865
uniprot id: B9K877
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

309803:CTN RS08855
gene id: 309803:CTN_RS08855
uniprot id: B9KAG8
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS09560
gene id: 309803:CTN_RS09560
uniprot id: B9KAW3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

309803:CTN RS04405
gene id: 309803:CTN_RS04405
uniprot id: B9K7Y6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS03625
gene id: 309803:CTN_RS03625
uniprot id: B9K7H7
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

309803:CTN RS02775
gene id: 309803:CTN_RS02775
uniprot id: B9K6Z3
names: Similarity
messages: Belongs to the TrpF family.

309803:CTN RS04455
gene id: 309803:CTN_RS04455
uniprot id: B9K7Z6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

309803:CTN RS01040
gene id: 309803:CTN_RS01040
uniprot id: B9KBJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

309803:CTN RS06460
gene id: 309803:CTN_RS06460
uniprot id: B9K934
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309803:CTN RS05545
gene id: 309803:CTN_RS05545
uniprot id: B9K8K8
names: Similarity
messages: Belongs to the ETF-QO/FixC family.

309803:CTN RS00800
gene id: 309803:CTN_RS00800
uniprot id: B9KBE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309803:CTN RS03750
gene id: 309803:CTN_RS03750
uniprot id: B9K7K4
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309803:CTN RS08405
gene id: 309803:CTN_RS08405
uniprot id: B9KA78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

309803:CTN RS00440
gene id: 309803:CTN_RS00440
uniprot id: B9KB74
names: Similarity
messages: Belongs to the peptidase S1C family.

309803:CTN RS01460
gene id: 309803:CTN_RS01460
uniprot id: B9KBS6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

309803:CTN RS00720
gene id: 309803:CTN_RS00720
uniprot id: B9KBD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

309803:CTN RS02235
gene id: 309803:CTN_RS02235
uniprot id: B9K6P8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

309803:CTN RS09415
gene id: 309803:CTN_RS09415
uniprot id: B9KAT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

309803:CTN RS01495
gene id: 309803:CTN_RS01495
uniprot id: B9KBT4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

309803:CTN RS08700
gene id: 309803:CTN_RS08700
uniprot id: B9KAD6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Binds two Mg(2+) per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn(2+) or Ca(2+).
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

309803:CTN RS05900
gene id: 309803:CTN_RS05900
uniprot id: Q9Z4S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

309803:CTN RS04990
gene id: 309803:CTN_RS04990
uniprot id: B9K8A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that bind and probably mediate the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

309803:CTN RS04450
gene id: 309803:CTN_RS04450
uniprot id: B9K7Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

309803:CTN RS02735
gene id: 309803:CTN_RS02735
uniprot id: B9K6Y6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

309803:CTN RS01125
gene id: 309803:CTN_RS01125
uniprot id: B9KBK9
names: Similarity
messages: Belongs to the FGGY kinase family.

309803:CTN RS08840
gene id: 309803:CTN_RS08840
uniprot id: B9KAG5
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06925
gene id: 309803:CTN_RS06925
uniprot id: B9K9C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm

309803:CTN RS09460
gene id: 309803:CTN_RS09460
uniprot id: B9KAU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

309803:CTN RS00175
gene id: 309803:CTN_RS00175
uniprot id: B9KB15
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

309803:CTN RS00935
gene id: 309803:CTN_RS00935
uniprot id: B9KBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS02310
gene id: 309803:CTN_RS02310
uniprot id: B9K6R2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309803:CTN RS08770
gene id: 309803:CTN_RS08770
uniprot id: B9KAF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

309803:CTN RS05035
gene id: 309803:CTN_RS05035
uniprot id: B9K8B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

309803:CTN RS06385
gene id: 309803:CTN_RS06385
uniprot id: B9K920
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS08865
gene id: 309803:CTN_RS08865
uniprot id: B9KAH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

309803:CTN RS02715
gene id: 309803:CTN_RS02715
uniprot id: B9K6Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

309803:CTN RS05325
gene id: 309803:CTN_RS05325
uniprot id: B9K8G8
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

309803:CTN RS05470
gene id: 309803:CTN_RS05470
uniprot id: B9K8J3
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02840
gene id: 309803:CTN_RS02840
uniprot id: B9K707
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

309803:CTN RS05110
gene id: 309803:CTN_RS05110
uniprot id: B9K8C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell inner membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

309803:CTN RS04810
gene id: 309803:CTN_RS04810
uniprot id: B9K866
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

309803:CTN RS06815
gene id: 309803:CTN_RS06815
uniprot id: B9K9A5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309803:CTN RS05055
gene id: 309803:CTN_RS05055
uniprot id: B9K8B5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

309803:CTN RS05190
gene id: 309803:CTN_RS05190
uniprot id: B9K8E0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

309803:CTN RS04890
gene id: 309803:CTN_RS04890
uniprot id: B9K882
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

309803:CTN RS05290
gene id: 309803:CTN_RS05290
uniprot id: B9K8G1
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

309803:CTN RS07450
gene id: 309803:CTN_RS07450
uniprot id: B9K9N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

309803:CTN RS09230
gene id: 309803:CTN_RS09230
uniprot id: B9KAP7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS00195
gene id: 309803:CTN_RS00195
uniprot id: B9KB19
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS04270
gene id: 309803:CTN_RS04270
uniprot id: B9K7W1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

309803:CTN RS07370
gene id: 309803:CTN_RS07370
uniprot id: B9K9L7
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

309803:CTN RS08410
gene id: 309803:CTN_RS08410
uniprot id: B9KA79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

309803:CTN RS03275
gene id: 309803:CTN_RS03275
uniprot id: B9K799
names: Function
names: Similarity
messages: Belongs to the THEP1 NTPase family.
messages: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.

309803:CTN RS05710
gene id: 309803:CTN_RS05710
uniprot id: B9K8P1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

309803:CTN RS09580
gene id: 309803:CTN_RS09580
uniprot id: B9KAW7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

309803:CTN RS04955
gene id: 309803:CTN_RS04955
uniprot id: B9K895
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

309803:CTN RS05935
gene id: 309803:CTN_RS05935
uniprot id: B9K8T5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

309803:CTN RS07315
gene id: 309803:CTN_RS07315
uniprot id: B9K9K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

309803:CTN RS03305
gene id: 309803:CTN_RS03305
uniprot id: B9K7A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS02070
gene id: 309803:CTN_RS02070
uniprot id: B9KC52
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

309803:CTN RS08725
gene id: 309803:CTN_RS08725
uniprot id: B9KAE1
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

309803:CTN RS09550
gene id: 309803:CTN_RS09550
uniprot id: B9KAW1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

309803:CTN RS03830
gene id: 309803:CTN_RS03830
uniprot id: B9K7M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS08455
gene id: 309803:CTN_RS08455
uniprot id: B9KA88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MetA family.
messages: Cytoplasm
messages: Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.

309803:CTN RS06060
gene id: 309803:CTN_RS06060
uniprot id: B9K8V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

309803:CTN RS03995
gene id: 309803:CTN_RS03995
uniprot id: B9K7Q5
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309803:CTN RS06835
gene id: 309803:CTN_RS06835
uniprot id: B9K9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

309803:CTN RS02245
gene id: 309803:CTN_RS02245
uniprot id: B9K6Q0
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06570
gene id: 309803:CTN_RS06570
uniprot id: B9K956
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

309803:CTN RS04775
gene id: 309803:CTN_RS04775
uniprot id: B9K860
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

309803:CTN RS07260
gene id: 309803:CTN_RS07260
uniprot id: B9K9J3
names: Similarity
messages: Belongs to the bacterial secretin family.

309803:CTN RS06790
gene id: 309803:CTN_RS06790
uniprot id: B9K9A0
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

309803:CTN RS03720
gene id: 309803:CTN_RS03720
uniprot id: B9K7J8
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

309803:CTN RS08325
gene id: 309803:CTN_RS08325
uniprot id: B9KA61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Cell membrane
messages: Membrane
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

309803:CTN RS06375
gene id: 309803:CTN_RS06375
uniprot id: B9K918
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS01160
gene id: 309803:CTN_RS01160
uniprot id: B9KBL6
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06195
gene id: 309803:CTN_RS06195
uniprot id: B9K8Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

309803:CTN RS05905
gene id: 309803:CTN_RS05905
uniprot id: B9K8S7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.

309803:CTN RS04080
gene id: 309803:CTN_RS04080
uniprot id: B9K7S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

309803:CTN RS07320
gene id: 309803:CTN_RS07320
uniprot id: B9K9K5
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS05705
gene id: 309803:CTN_RS05705
uniprot id: B9K8P0
names: Similarity
messages: Belongs to the acylphosphatase family.

309803:CTN RS01685
gene id: 309803:CTN_RS01685
uniprot id: B9KBX1
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

309803:CTN RS02855
gene id: 309803:CTN_RS02855
uniprot id: B9K710
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

309803:CTN RS04585
gene id: 309803:CTN_RS04585
uniprot id: B9K823
names: Similarity
messages: Belongs to the YggT family.

309803:CTN RS09590
gene id: 309803:CTN_RS09590
uniprot id: B9KAW9
names: Similarity
messages: Belongs to the SAM hydrolase / SAM-dependent halogenase family.

309803:CTN RS02945
gene id: 309803:CTN_RS02945
uniprot id: B9K730
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06625
gene id: 309803:CTN_RS06625
uniprot id: B9K968
names: Similarity
messages: Belongs to the PurH family.

309803:CTN RS09490
gene id: 309803:CTN_RS09490
uniprot id: B9KAU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

309803:CTN RS05630
gene id: 309803:CTN_RS05630
uniprot id: B9K8M5
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02575
gene id: 309803:CTN_RS02575
uniprot id: B9K6V3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309803:CTN RS00680
gene id: 309803:CTN_RS00680
uniprot id: B9KBC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

309803:CTN RS07605
gene id: 309803:CTN_RS07605
uniprot id: B9K9R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

309803:CTN RS02230
gene id: 309803:CTN_RS02230
uniprot id: B9K6P7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell inner membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

309803:CTN RS01570
gene id: 309803:CTN_RS01570
uniprot id: B9KBU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

309803:CTN RS04595
gene id: 309803:CTN_RS04595
uniprot id: B9K825
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

309803:CTN RS03360
gene id: 309803:CTN_RS03360
uniprot id: B9K7B8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

309803:CTN RS07595
gene id: 309803:CTN_RS07595
uniprot id: B9K9R3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

309803:CTN RS00590
gene id: 309803:CTN_RS00590
uniprot id: B9KBA5
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS09395
gene id: 309803:CTN_RS09395
uniprot id: B9KAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

309803:CTN RS07950
gene id: 309803:CTN_RS07950
uniprot id: B9K9Y7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

309803:CTN RS00580
gene id: 309803:CTN_RS00580
uniprot id: B9KBA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

309803:CTN RS03980
gene id: 309803:CTN_RS03980
uniprot id: B9K7Q1
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

309803:CTN RS04710
gene id: 309803:CTN_RS04710
uniprot id: B9K847
names: Similarity
messages: Belongs to the asp23 family.

309803:CTN RS02040
gene id: 309803:CTN_RS02040
uniprot id: B9KC45
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

309803:CTN RS08575
gene id: 309803:CTN_RS08575
uniprot id: B9KAB1
names: Similarity
messages: Belongs to the ribF family.

309803:CTN RS06350
gene id: 309803:CTN_RS06350
uniprot id: B9K913
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

309803:CTN RS01590
gene id: 309803:CTN_RS01590
uniprot id: B9KBV3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

309803:CTN RS00885
gene id: 309803:CTN_RS00885
uniprot id: B9KBG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS02790
gene id: 309803:CTN_RS02790
uniprot id: B9K6Z7
names: Subcellular Location Annotation
messages: Cytoplasm

309803:CTN RS09285
gene id: 309803:CTN_RS09285
uniprot id: B9KAQ8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

309803:CTN RS02375
gene id: 309803:CTN_RS02375
uniprot id: B9K6S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS01505
gene id: 309803:CTN_RS01505
uniprot id: B9KBT6
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

309803:CTN RS06845
gene id: 309803:CTN_RS06845
uniprot id: B9K9B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.

309803:CTN RS03110
gene id: 309803:CTN_RS03110
uniprot id: B9K764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS04580
gene id: 309803:CTN_RS04580
uniprot id: B9K822
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

309803:CTN RS04900
gene id: 309803:CTN_RS04900
uniprot id: B9K884
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

309803:CTN RS00545
gene id: 309803:CTN_RS00545
uniprot id: B9KB96
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family.

309803:CTN RS02085
gene id: 309803:CTN_RS02085
uniprot id: B9KC55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

309803:CTN RS09325
gene id: 309803:CTN_RS09325
uniprot id: B9KAR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS03195
gene id: 309803:CTN_RS03195
uniprot id: B9K782
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 67 family.
messages: Homodimer.

309803:CTN RS03355
gene id: 309803:CTN_RS03355
uniprot id: B9K7B5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

309803:CTN RS05040
gene id: 309803:CTN_RS05040
uniprot id: B9K8B2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

309803:CTN RS08345
gene id: 309803:CTN_RS08345
uniprot id: B9KA65
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

309803:CTN RS02135
gene id: 309803:CTN_RS02135
uniprot id: B9K6M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

309803:CTN RS07295
gene id: 309803:CTN_RS07295
uniprot id: B9K9K0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309803:CTN RS06740
gene id: 309803:CTN_RS06740
uniprot id: B9K990
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309803:CTN RS08845
gene id: 309803:CTN_RS08845
uniprot id: B9KAG6
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS04590
gene id: 309803:CTN_RS04590
uniprot id: B9K824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

309803:CTN RS01885
gene id: 309803:CTN_RS01885
uniprot id: B9KC12
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

309803:CTN RS05885
gene id: 309803:CTN_RS05885
uniprot id: B9K8S3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

309803:CTN RS04085
gene id: 309803:CTN_RS04085
uniprot id: B9K7S4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

309803:CTN RS01030
gene id: 309803:CTN_RS01030
uniprot id: B9KBJ4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

309803:CTN RS00445
gene id: 309803:CTN_RS00445
uniprot id: B9KB75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell inner membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

309803:CTN RS05720
gene id: 309803:CTN_RS05720
uniprot id: B9K8P3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpA RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpB.

309803:CTN RS00535
gene id: 309803:CTN_RS00535
uniprot id: B9KB94
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

309803:CTN RS03745
gene id: 309803:CTN_RS03745
uniprot id: B9K7K3
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

309803:CTN RS04155
gene id: 309803:CTN_RS04155
uniprot id: B9K7T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell inner membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

309803:CTN RS02080
gene id: 309803:CTN_RS02080
uniprot id: B9KC54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

309803:CTN RS03855
gene id: 309803:CTN_RS03855
uniprot id: B9K7M6
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 94 family.
messages: Catalyzes the phosphorolysis of cellobiose, yielding glucose 1-phosphate and glucose. Is inactive against cellotriose and the disaccharides lactose, chitobiose and xylobiose. May be the primary enzyme for processing cellobiose in T.neapolitana.

309803:CTN RS05930
gene id: 309803:CTN_RS05930
uniprot id: B9K8T4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

309803:CTN RS09110
gene id: 309803:CTN_RS09110
uniprot id: B9KAM2
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).

309803:CTN RS08305
gene id: 309803:CTN_RS08305
uniprot id: B9KA57
names: Function
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

309803:CTN RS05725
gene id: 309803:CTN_RS05725
uniprot id: B9K8P4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein uS19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein uS19.

309803:CTN RS02240
gene id: 309803:CTN_RS02240
uniprot id: B9K6P9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309803:CTN RS01095
gene id: 309803:CTN_RS01095
uniprot id: B9KBK3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the thymidylate synthase ThyX family.
messages: Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
messages: Homotetramer.

309803:CTN RS04295
gene id: 309803:CTN_RS04295
uniprot id: B9K7W3
names: Subcellular Location Annotation
messages: Cytoplasm

309803:CTN RS06500
gene id: 309803:CTN_RS06500
uniprot id: B9K942
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

309803:CTN RS04165
gene id: 309803:CTN_RS04165
uniprot id: B9K7T9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

309803:CTN RS00825
gene id: 309803:CTN_RS00825
uniprot id: B9KBF4
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02170
gene id: 309803:CTN_RS02170
uniprot id: B9K6N5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309803:CTN RS05590
gene id: 309803:CTN_RS05590
uniprot id: B9K8L7
names: Subcellular Location Annotation
messages: Periplasm

309803:CTN RS01105
gene id: 309803:CTN_RS01105
uniprot id: B9KBK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS05155
gene id: 309803:CTN_RS05155
uniprot id: B9K8D3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

309803:CTN RS03085
gene id: 309803:CTN_RS03085
uniprot id: B9K759
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

309803:CTN RS04190
gene id: 309803:CTN_RS04190
uniprot id: B9K7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.
messages: Cytoplasm
messages: Interacts with 100S ribosomes.
messages: Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.

309803:CTN RS04920
gene id: 309803:CTN_RS04920
uniprot id: B9K888
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

309803:CTN RS04975
gene id: 309803:CTN_RS04975
uniprot id: B9K899
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

309803:CTN RS03585
gene id: 309803:CTN_RS03585
uniprot id: B9K7G9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

309803:CTN RS05645
gene id: 309803:CTN_RS05645
uniprot id: B9K8M8
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309803:CTN RS05120
gene id: 309803:CTN_RS05120
uniprot id: B9K8C6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A probable RNA chaperone. Forms a complex with KhpA which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.
messages: Belongs to the KhpB RNA-binding protein family.
messages: Cytoplasm
messages: Forms a complex with KhpA.
messages: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH and R3H).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS00600
gene id: 309803:CTN_RS00600
uniprot id: B9KBA7
names: Similarity
messages: Belongs to the class-I fumarase family.

309803:CTN RS07245
gene id: 309803:CTN_RS07245
uniprot id: B9K9J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

309803:CTN RS08875
gene id: 309803:CTN_RS08875
uniprot id: B9KAH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BioY family.
messages: Cell membrane

309803:CTN RS03880
gene id: 309803:CTN_RS03880
uniprot id: B9K7N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS04730
gene id: 309803:CTN_RS04730
uniprot id: B9K851
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

309803:CTN RS01525
gene id: 309803:CTN_RS01525
uniprot id: B9KBU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

309803:CTN RS04160
gene id: 309803:CTN_RS04160
uniprot id: B9K7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase delta chain family.
messages: Cell inner membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

309803:CTN RS09085
gene id: 309803:CTN_RS09085
uniprot id: B9KAL5
names: Similarity
messages: Belongs to the bacterial flagellin family.

309803:CTN RS04660
gene id: 309803:CTN_RS04660
uniprot id: B9K838
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

309803:CTN RS09370
gene id: 309803:CTN_RS09370
uniprot id: B9KAS5
names: Similarity
messages: Belongs to the CinA family.

309803:CTN RS03370
gene id: 309803:CTN_RS03370
uniprot id: B9K7C0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.
messages: Cell inner membrane
messages: Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane
messages: Na(+) is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

309803:CTN RS04320
gene id: 309803:CTN_RS04320
uniprot id: B9K7W8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

309803:CTN RS08060
gene id: 309803:CTN_RS08060
uniprot id: B9KA10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

309803:CTN RS00750
gene id: 309803:CTN_RS00750
uniprot id: B9KBD7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS08810
gene id: 309803:CTN_RS08810
uniprot id: B9KAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS04200
gene id: 309803:CTN_RS04200
uniprot id: B9K7U6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

309803:CTN RS03835
gene id: 309803:CTN_RS03835
uniprot id: B9K7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS06820
gene id: 309803:CTN_RS06820
uniprot id: B9K9A6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

309803:CTN RS04550
gene id: 309803:CTN_RS04550
uniprot id: B9K815
names: Function
names: Similarity
messages: Belongs to the V-ATPase D subunit family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

309803:CTN RS08750
gene id: 309803:CTN_RS08750
uniprot id: B9KAE7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309803:CTN RS05895
gene id: 309803:CTN_RS05895
uniprot id: Q9Z4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

309803:CTN RS07980
gene id: 309803:CTN_RS07980
uniprot id: B9K9Z3
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

309803:CTN RS00160
gene id: 309803:CTN_RS00160
uniprot id: B9KB12
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

309803:CTN RS04360
gene id: 309803:CTN_RS04360
uniprot id: B9K7X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Membrane

309803:CTN RS04410
gene id: 309803:CTN_RS04410
uniprot id: B9K7Y7
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

309803:CTN RS01520
gene id: 309803:CTN_RS01520
uniprot id: B9KBT9
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02220
gene id: 309803:CTN_RS02220
uniprot id: B9K6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

309803:CTN RS02615
gene id: 309803:CTN_RS02615
uniprot id: B9K6W1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

309803:CTN RS00650
gene id: 309803:CTN_RS00650
uniprot id: B9KBB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309803:CTN RS04475
gene id: 309803:CTN_RS04475
uniprot id: B9K800
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

309803:CTN RS07705
gene id: 309803:CTN_RS07705
uniprot id: B9K9T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS07550
gene id: 309803:CTN_RS07550
uniprot id: B9K9Q4
names: Similarity
messages: Belongs to the CutA family.

309803:CTN RS07445
gene id: 309803:CTN_RS07445
uniprot id: B9K9N2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

309803:CTN RS00375
gene id: 309803:CTN_RS00375
uniprot id: B9KB61
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

309803:CTN RS00525
gene id: 309803:CTN_RS00525
uniprot id: B9KB92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS05315
gene id: 309803:CTN_RS05315
uniprot id: B9K8G6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

309803:CTN RS01500
gene id: 309803:CTN_RS01500
uniprot id: B9KBT5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

309803:CTN RS06050
gene id: 309803:CTN_RS06050
uniprot id: B9K8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS05185
gene id: 309803:CTN_RS05185
uniprot id: B9K8D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Probably interacts with PlsX.

309803:CTN RS05140
gene id: 309803:CTN_RS05140
uniprot id: B9K8D0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

309803:CTN RS02940
gene id: 309803:CTN_RS02940
uniprot id: B9K729
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02630
gene id: 309803:CTN_RS02630
uniprot id: B9K6W4
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

309803:CTN RS04315
gene id: 309803:CTN_RS04315
uniprot id: B9K7W7
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS01265
gene id: 309803:CTN_RS01265
uniprot id: B9KBN7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

309803:CTN RS00690
gene id: 309803:CTN_RS00690
uniprot id: B9KBC5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Monomer.

309803:CTN RS02905
gene id: 309803:CTN_RS02905
uniprot id: B9K721
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS07435
gene id: 309803:CTN_RS07435
uniprot id: B9K9N0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

309803:CTN RS06795
gene id: 309803:CTN_RS06795
uniprot id: B9K9A1
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06645
gene id: 309803:CTN_RS06645
uniprot id: B9K972
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

309803:CTN RS04330
gene id: 309803:CTN_RS04330
uniprot id: B9K7X0
names: Similarity
messages: Belongs to the RemA family.

309803:CTN RS00850
gene id: 309803:CTN_RS00850
uniprot id: B9KBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS04445
gene id: 309803:CTN_RS04445
uniprot id: B9K7Z4
names: Similarity
messages: Belongs to the IMPACT family.

309803:CTN RS04850
gene id: 309803:CTN_RS04850
uniprot id: B9K874
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

309803:CTN RS07690
gene id: 309803:CTN_RS07690
uniprot id: B9K9T3
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS08500
gene id: 309803:CTN_RS08500
uniprot id: B9KA96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

309803:CTN RS05580
gene id: 309803:CTN_RS05580
uniprot id: B9K8L5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgI family.
messages: Periplasm
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

309803:CTN RS01660
gene id: 309803:CTN_RS01660
uniprot id: B9KBW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

309803:CTN RS05010
gene id: 309803:CTN_RS05010
uniprot id: B9K8A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell inner membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

309803:CTN RS03730
gene id: 309803:CTN_RS03730
uniprot id: B9K7K0
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

309803:CTN RS08830
gene id: 309803:CTN_RS08830
uniprot id: B9KAG3
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309803:CTN RS02320
gene id: 309803:CTN_RS02320
uniprot id: B9K6R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

309803:CTN RS08935
gene id: 309803:CTN_RS08935
uniprot id: B9KAI4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the THI4 family.
messages: Homooctamer; tetramer of dimers.
messages: Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS06950
gene id: 309803:CTN_RS06950
uniprot id: B9K9D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

309803:CTN RS00515
gene id: 309803:CTN_RS00515
uniprot id: B9KB90
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

309803:CTN RS05755
gene id: 309803:CTN_RS05755
uniprot id: B9K8Q0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.

309803:CTN RS02955
gene id: 309803:CTN_RS02955
uniprot id: B9K732
names: Similarity
messages: Belongs to the BMP lipoprotein family.

309803:CTN RS02395
gene id: 309803:CTN_RS02395
uniprot id: B9K6T0
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

309803:CTN RS05270
gene id: 309803:CTN_RS05270
uniprot id: B9K8F7
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

309803:CTN RS00325
gene id: 309803:CTN_RS00325
uniprot id: B9KB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309803:CTN RS06900
gene id: 309803:CTN_RS06900
uniprot id: B9K9C2
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

309803:CTN RS06595
gene id: 309803:CTN_RS06595
uniprot id: B9K962
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

309803:CTN RS08160
gene id: 309803:CTN_RS08160
uniprot id: B9KA29
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

309803:CTN RS10145
gene id: 309803:CTN_RS10145
uniprot id: B9K9W8
names: Similarity
messages: In the C-terminal section; belongs to the transposase 35 family.

309803:CTN RS03150
gene id: 309803:CTN_RS03150
uniprot id: B9K773
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

309803:CTN RS01270
gene id: 309803:CTN_RS01270
uniprot id: B9KBN8
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

309803:CTN RS03125
gene id: 309803:CTN_RS03125
uniprot id: B9K767
names: Function
names: Similarity
messages: Belongs to the mannonate dehydratase family.
messages: Catalyzes the dehydration of D-mannonate.

309803:CTN RS04765
gene id: 309803:CTN_RS04765
uniprot id: B9K858
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS08190
gene id: 309803:CTN_RS08190
uniprot id: B9KA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

309803:CTN RS00925
gene id: 309803:CTN_RS00925
uniprot id: B9KBH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

309803:CTN RS06615
gene id: 309803:CTN_RS06615
uniprot id: B9K966
names: Similarity
messages: Belongs to the AIR synthase family.

309803:CTN RS04895
gene id: 309803:CTN_RS04895
uniprot id: B9K883
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

309803:CTN RS09595
gene id: 309803:CTN_RS09595
uniprot id: B9KAX0
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

309803:CTN RS02730
gene id: 309803:CTN_RS02730
uniprot id: B9K6Y5
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

309803:CTN RS01260
gene id: 309803:CTN_RS01260
uniprot id: B9KBN6
names: Similarity
messages: Belongs to the creatininase superfamily.

309803:CTN RS06685
gene id: 309803:CTN_RS06685
uniprot id: B9K979
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309803:CTN RS08555
gene id: 309803:CTN_RS08555
uniprot id: B9KAA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

309803:CTN RS05510
gene id: 309803:CTN_RS05510
uniprot id: B9K8K0
names: Similarity
messages: Belongs to the glycosyl hydrolase 12 (cellulase H) family.

309803:CTN RS05940
gene id: 309803:CTN_RS05940
uniprot id: B9K8T6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

309803:CTN RS02190
gene id: 309803:CTN_RS02190
uniprot id: B9K6N9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

309803:CTN RS01110
gene id: 309803:CTN_RS01110
uniprot id: B9KBK6
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

309803:CTN RS03325
gene id: 309803:CTN_RS03325
uniprot id: B9K7A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309803:CTN RS07960
gene id: 309803:CTN_RS07960
uniprot id: B9K9Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsuA/YedE (TC 9.B.102) family.
messages: Cell inner membrane
messages: Membrane

309803:CTN RS01790
gene id: 309803:CTN_RS01790
uniprot id: B9KBZ2
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS04090
gene id: 309803:CTN_RS04090
uniprot id: B9K7S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

309803:CTN RS01930
gene id: 309803:CTN_RS01930
uniprot id: B9KC21
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 2 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

309803:CTN RS09115
gene id: 309803:CTN_RS09115
uniprot id: B9KAM3
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 4 family.
messages: Binds 1 NAD(+) per subunit.

309803:CTN RS03670
gene id: 309803:CTN_RS03670
uniprot id: B9K7I7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 2 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

309803:CTN RS02165
gene id: 309803:CTN_RS02165
uniprot id: B9K6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309803:CTN RS03555
gene id: 309803:CTN_RS03555
uniprot id: B9K7G3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

309803:CTN RS01795
gene id: 309803:CTN_RS01795
uniprot id: B9KBZ3
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS00555
gene id: 309803:CTN_RS00555
uniprot id: B9KB98
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.

309803:CTN RS09920
gene id: 309803:CTN_RS09920
uniprot id: B9KB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS04545
gene id: 309803:CTN_RS04545
uniprot id: B9K814
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit.

309803:CTN RS00880
gene id: 309803:CTN_RS00880
uniprot id: B9KBG5
names: Similarity
messages: Belongs to the UPF0045 family.

309803:CTN RS07070
gene id: 309803:CTN_RS07070
uniprot id: B9K9F6
names: Similarity
messages: Belongs to the UPF0173 family.

309803:CTN RS06205
gene id: 309803:CTN_RS06205
uniprot id: B9K8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

309803:CTN RS07430
gene id: 309803:CTN_RS07430
uniprot id: B9K9M9
names: Similarity
messages: Belongs to the archease family.

309803:CTN RS08620
gene id: 309803:CTN_RS08620
uniprot id: B9KAB9
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

309803:CTN RS02335
gene id: 309803:CTN_RS02335
uniprot id: B9K6R7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

309803:CTN RS05170
gene id: 309803:CTN_RS05170
uniprot id: B9K8D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

309803:CTN RS09475
gene id: 309803:CTN_RS09475
uniprot id: B9KAU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

309803:CTN RS00860
gene id: 309803:CTN_RS00860
uniprot id: B9KBG1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class U subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.

309803:CTN RS09425
gene id: 309803:CTN_RS09425
uniprot id: B9KAT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

309803:CTN RS00185
gene id: 309803:CTN_RS00185
uniprot id: B9KB17
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS08930
gene id: 309803:CTN_RS08930
uniprot id: B9KAI3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

309803:CTN RS01055
gene id: 309803:CTN_RS01055
uniprot id: B9KBJ9
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

309803:CTN RS04930
gene id: 309803:CTN_RS04930
uniprot id: B9K890
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

309803:CTN RS08910
gene id: 309803:CTN_RS08910
uniprot id: B9KAH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

309803:CTN RS08885
gene id: 309803:CTN_RS08885
uniprot id: B9KAH4
names: Similarity
messages: Belongs to the ComB family.

309803:CTN RS01945
gene id: 309803:CTN_RS01945
uniprot id: B9KC25
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Short' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Non-allosteric.

309803:CTN RS03090
gene id: 309803:CTN_RS03090
uniprot id: B9K760
names: Similarity
messages: Belongs to the glycosyl hydrolase 26 family.

309803:CTN RS03540
gene id: 309803:CTN_RS03540
uniprot id: B9K7F8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

309803:CTN RS08610
gene id: 309803:CTN_RS08610
uniprot id: B9KAB7
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

309803:CTN RS09625
gene id: 309803:CTN_RS09625
uniprot id: B9KAX6
names: Similarity
messages: Belongs to the bacterial secretin family.

309803:CTN RS05025
gene id: 309803:CTN_RS05025
uniprot id: B9K8A9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

309803:CTN RS00540
gene id: 309803:CTN_RS00540
uniprot id: B9KB95
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS04345
gene id: 309803:CTN_RS04345
uniprot id: B9K7X3
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

309803:CTN RS04665
gene id: 309803:CTN_RS04665
uniprot id: B9K839
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

309803:CTN RS06125
gene id: 309803:CTN_RS06125
uniprot id: B9K8W9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

309803:CTN RS02290
gene id: 309803:CTN_RS02290
uniprot id: B9K6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Cell inner membrane
messages: Membrane
messages: One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation.

309803:CTN RS00625
gene id: 309803:CTN_RS00625
uniprot id: B9KBB2
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS03605
gene id: 309803:CTN_RS03605
uniprot id: B9K7H3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

309803:CTN RS01995
gene id: 309803:CTN_RS01995
uniprot id: B9KC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS09015
gene id: 309803:CTN_RS09015
uniprot id: B9KAK1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

309803:CTN RS02100
gene id: 309803:CTN_RS02100
uniprot id: B9KC58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

309803:CTN RS05890
gene id: 309803:CTN_RS05890
uniprot id: Q9Z4S1
names: Activity Regulation
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Competitively inhibited by L-ornithine.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e. capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

309803:CTN RS05235
gene id: 309803:CTN_RS05235
uniprot id: B9K8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

309803:CTN RS09600
gene id: 309803:CTN_RS09600
uniprot id: B9KAX1
names: Similarity
messages: Belongs to the desulfoferrodoxin family.

309803:CTN RS07465
gene id: 309803:CTN_RS07465
uniprot id: B9K9N6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

309803:CTN RS08615
gene id: 309803:CTN_RS08615
uniprot id: B9KAB8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

309803:CTN RS02785
gene id: 309803:CTN_RS02785
uniprot id: B9K6Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

309803:CTN RS07040
gene id: 309803:CTN_RS07040
uniprot id: B9K9F0
names: Similarity
messages: Belongs to the glycogen phosphorylase family.

309803:CTN RS06805
gene id: 309803:CTN_RS06805
uniprot id: B9K9A3
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS09020
gene id: 309803:CTN_RS09020
uniprot id: B9KAK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

309803:CTN RS04205
gene id: 309803:CTN_RS04205
uniprot id: B9K7U7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS06055
gene id: 309803:CTN_RS06055
uniprot id: B9K8V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS09180
gene id: 309803:CTN_RS09180
uniprot id: B9KAN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS06885
gene id: 309803:CTN_RS06885
uniprot id: B9K9B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS03260
gene id: 309803:CTN_RS03260
uniprot id: B9K795
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

309803:CTN RS04335
gene id: 309803:CTN_RS04335
uniprot id: B9K7X1
names: Similarity
messages: Belongs to the YicC/YloC family.

309803:CTN RS06005
gene id: 309803:CTN_RS06005
uniprot id: B9K8U7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

309803:CTN RS05095
gene id: 309803:CTN_RS05095
uniprot id: B9K8C2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pseudouridine-5'-phosphate glycosidase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
messages: Homotrimer.

309803:CTN RS01955
gene id: 309803:CTN_RS01955
uniprot id: B9KC27
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02305
gene id: 309803:CTN_RS02305
uniprot id: B9K6R1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

309803:CTN RS05165
gene id: 309803:CTN_RS05165
uniprot id: B9K8D5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

309803:CTN RS05085
gene id: 309803:CTN_RS05085
uniprot id: B9K8C0
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

309803:CTN RS00970
gene id: 309803:CTN_RS00970
uniprot id: B9KBI1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glutaminase PdxT/SNO family.
messages: Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
messages: In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.

309803:CTN RS03915
gene id: 309803:CTN_RS03915
uniprot id: B9K7N8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

309803:CTN RS01580
gene id: 309803:CTN_RS01580
uniprot id: B9KBV1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

309803:CTN RS04985
gene id: 309803:CTN_RS04985
uniprot id: B9K8A1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

309803:CTN RS08140
gene id: 309803:CTN_RS08140
uniprot id: B9KA26
names: Similarity
messages: Belongs to the glutamine synthetase family.

309803:CTN RS07625
gene id: 309803:CTN_RS07625
uniprot id: B9K9R9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

309803:CTN RS01050
gene id: 309803:CTN_RS01050
uniprot id: B9KBJ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

309803:CTN RS04795
gene id: 309803:CTN_RS04795
uniprot id: B9K863
names: Subunit
messages: Homodimer.

309803:CTN RS06020
gene id: 309803:CTN_RS06020
uniprot id: B9K8V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS02140
gene id: 309803:CTN_RS02140
uniprot id: B9K6M9
names: Similarity
messages: Belongs to the DprA/Smf family.

309803:CTN RS01655
gene id: 309803:CTN_RS01655
uniprot id: B9KBW6
names: Function
names: Similarity
messages: Belongs to the OMP decarboxylase family.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

309803:CTN RS06650
gene id: 309803:CTN_RS06650
uniprot id: B9K973
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PurS family.
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

309803:CTN RS03530
gene id: 309803:CTN_RS03530
uniprot id: B9K7F6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

309803:CTN RS09340
gene id: 309803:CTN_RS09340
uniprot id: B9KAR9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

309803:CTN RS06695
gene id: 309803:CTN_RS06695
uniprot id: B9K981
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS08685
gene id: 309803:CTN_RS08685
uniprot id: B9KAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

309803:CTN RS04540
gene id: 309803:CTN_RS04540
uniprot id: B9K813
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

309803:CTN RS06225
gene id: 309803:CTN_RS06225
uniprot id: B9K8Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

309803:CTN RS05965
gene id: 309803:CTN_RS05965
uniprot id: B9K8U1
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

309803:CTN RS03120
gene id: 309803:CTN_RS03120
uniprot id: B9K766
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

309803:CTN RS02155
gene id: 309803:CTN_RS02155
uniprot id: B9K6N2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309803:CTN RS04175
gene id: 309803:CTN_RS04175
uniprot id: B9K7U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

309803:CTN RS06120
gene id: 309803:CTN_RS06120
uniprot id: B9K8W8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

309803:CTN RS01175
gene id: 309803:CTN_RS01175
uniprot id: B9KBL9
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS03925
gene id: 309803:CTN_RS03925
uniprot id: B9K7P0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein uS12.
messages: Cytoplasm

309803:CTN RS03520
gene id: 309803:CTN_RS03520
uniprot id: B9K7F4
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

309803:CTN RS02050
gene id: 309803:CTN_RS02050
uniprot id: B9KC48
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.

309803:CTN RS01675
gene id: 309803:CTN_RS01675
uniprot id: B9KBX0
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.

309803:CTN RS03510
gene id: 309803:CTN_RS03510
uniprot id: B9K7F2
names: Function
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

309803:CTN RS05020
gene id: 309803:CTN_RS05020
uniprot id: B9K8A8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

309803:CTN RS05585
gene id: 309803:CTN_RS05585
uniprot id: B9K8L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.

309803:CTN RS00755
gene id: 309803:CTN_RS00755
uniprot id: B9KBD8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

309803:CTN RS03800
gene id: 309803:CTN_RS03800
uniprot id: B9K7L5
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

309803:CTN RS04180
gene id: 309803:CTN_RS04180
uniprot id: B9K7U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell inner membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

309803:CTN RS06515
gene id: 309803:CTN_RS06515
uniprot id: B9K945
names: Similarity
messages: Belongs to the glycosyl hydrolase 10 (cellulase F) family.

309803:CTN RS02215
gene id: 309803:CTN_RS02215
uniprot id: B9K6P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell inner membrane

309803:CTN RS05915
gene id: 309803:CTN_RS05915
uniprot id: B9K8T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

309803:CTN RS04950
gene id: 309803:CTN_RS04950
uniprot id: B9K894
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

309803:CTN RS09500
gene id: 309803:CTN_RS09500
uniprot id: B9KAV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

309803:CTN RS06390
gene id: 309803:CTN_RS06390
uniprot id: B9K921
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS03345
gene id: 309803:CTN_RS03345
uniprot id: Q0GC07
names: Similarity
messages: Belongs to the glycosyl hydrolase 3 family.

309803:CTN RS06100
gene id: 309803:CTN_RS06100
uniprot id: B9K8W5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

309803:CTN RS06875
gene id: 309803:CTN_RS06875
uniprot id: B9K9B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS06045
gene id: 309803:CTN_RS06045
uniprot id: B9K8V5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

309803:CTN RS07360
gene id: 309803:CTN_RS07360
uniprot id: B9K9L4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

309803:CTN RS02515
gene id: 309803:CTN_RS02515
uniprot id: B9K6U6
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

309803:CTN RS06490
gene id: 309803:CTN_RS06490
uniprot id: B9K940
names: Function
names: Similarity
messages: Antitoxin component of a type II toxin-antitoxin (TA) system.
messages: Belongs to the phD/YefM antitoxin family.

309803:CTN RS00120
gene id: 309803:CTN_RS00120
uniprot id: B9KB05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

309803:CTN RS01920
gene id: 309803:CTN_RS01920
uniprot id: B9KC19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS02205
gene id: 309803:CTN_RS02205
uniprot id: B9K6P2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS06560
gene id: 309803:CTN_RS06560
uniprot id: B9K954
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

309803:CTN RS01615
gene id: 309803:CTN_RS01615
uniprot id: B9KBV9
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS09270
gene id: 309803:CTN_RS09270
uniprot id: B9KAQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

309803:CTN RS03885
gene id: 309803:CTN_RS03885
uniprot id: B9K7N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS01455
gene id: 309803:CTN_RS01455
uniprot id: B9KBS5
names: Similarity
messages: Belongs to the peptidase M18 family.

309803:CTN RS08395
gene id: 309803:CTN_RS08395
uniprot id: B9KA76
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell inner membrane
messages: Membrane

309803:CTN RS05765
gene id: 309803:CTN_RS05765
uniprot id: B9K8Q2
names: Similarity
messages: Belongs to the TlyA family.

309803:CTN RS05690
gene id: 309803:CTN_RS05690
uniprot id: B9K8N7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

309803:CTN RS09455
gene id: 309803:CTN_RS09455
uniprot id: B9KAU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

309803:CTN RS06440
gene id: 309803:CTN_RS06440
uniprot id: B9K930
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS07120
gene id: 309803:CTN_RS07120
uniprot id: B9K9G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309803:CTN RS08880
gene id: 309803:CTN_RS08880
uniprot id: B9KAH3
names: Similarity
messages: Belongs to the fabD family.

309803:CTN RS04565
gene id: 309803:CTN_RS04565
uniprot id: B9K819
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

309803:CTN RS03030
gene id: 309803:CTN_RS03030
uniprot id: B9K748
names: Similarity
messages: Belongs to the MEMO1 family.

309803:CTN RS06040
gene id: 309803:CTN_RS06040
uniprot id: B9K8V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

309803:CTN RS09655
gene id: 309803:CTN_RS09655
uniprot id: B9K7D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

309803:CTN RS08480
gene id: 309803:CTN_RS08480
uniprot id: B9KA92
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS01940
gene id: 309803:CTN_RS01940
uniprot id: B9KC24
names: Similarity
messages: Belongs to the citrate synthase family.

309803:CTN RS04415
gene id: 309803:CTN_RS04415
uniprot id: B9K7Y8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

309803:CTN RS04780
gene id: 309803:CTN_RS04780
uniprot id: B9K861
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

309803:CTN RS03870
gene id: 309803:CTN_RS03870
uniprot id: B9K7M9
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

309803:CTN RS04940
gene id: 309803:CTN_RS04940
uniprot id: B9K892
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

309803:CTN RS05200
gene id: 309803:CTN_RS05200
uniprot id: B9K8E2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

309803:CTN RS06555
gene id: 309803:CTN_RS06555
uniprot id: B9K953
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS07630
gene id: 309803:CTN_RS07630
uniprot id: B9K9S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

309803:CTN RS04060
gene id: 309803:CTN_RS04060
uniprot id: B9K7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

309803:CTN RS08380
gene id: 309803:CTN_RS08380
uniprot id: B9KA72
names: Caution
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS06105
gene id: 309803:CTN_RS06105
uniprot id: B9K8W6
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

309803:CTN RS07440
gene id: 309803:CTN_RS07440
uniprot id: B9K9N1
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

309803:CTN RS01045
gene id: 309803:CTN_RS01045
uniprot id: B9KBJ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

309803:CTN RS05925
gene id: 309803:CTN_RS05925
uniprot id: B9K8T3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

309803:CTN RS06140
gene id: 309803:CTN_RS06140
uniprot id: B9K8X2
names: Similarity
messages: Belongs to the GSP E family.

309803:CTN RS01600
gene id: 309803:CTN_RS01600
uniprot id: B9KBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

309803:CTN RS09225
gene id: 309803:CTN_RS09225
uniprot id: B9KAP6
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

309803:CTN RS00155
gene id: 309803:CTN_RS00155
uniprot id: B9KB11
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

309803:CTN RS03245
gene id: 309803:CTN_RS03245
uniprot id: B9K792
names: Similarity
messages: Belongs to the peptidase M24B family.

309803:CTN RS02600
gene id: 309803:CTN_RS02600
uniprot id: B9K6V8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

309803:CTN RS00165
gene id: 309803:CTN_RS00165
uniprot id: B9KB13
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

309803:CTN RS00350
gene id: 309803:CTN_RS00350
uniprot id: B9KB55
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

309803:CTN RS02090
gene id: 309803:CTN_RS02090
uniprot id: B9KC56
names: Similarity
messages: Belongs to the UPF0111 family.

309803:CTN RS06590
gene id: 309803:CTN_RS06590
uniprot id: B9K961
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS01760
gene id: 309803:CTN_RS01760
uniprot id: B9KBY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS05205
gene id: 309803:CTN_RS05205
uniprot id: B9K8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

309803:CTN RS01755
gene id: 309803:CTN_RS01755
uniprot id: B9KBY5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

309803:CTN RS05215
gene id: 309803:CTN_RS05215
uniprot id: B9K8E5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS02345
gene id: 309803:CTN_RS02345
uniprot id: B9K6R9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

309803:CTN RS08240
gene id: 309803:CTN_RS08240
uniprot id: B9KA44
names: Cofactor
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309803:CTN RS09450
gene id: 309803:CTN_RS09450
uniprot id: B9KAU1
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

309803:CTN RS08560
gene id: 309803:CTN_RS08560
uniprot id: B9KAA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell inner membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

309803:CTN RS07145
gene id: 309803:CTN_RS07145
uniprot id: B9K9H0
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

309803:CTN RS04635
gene id: 309803:CTN_RS04635
uniprot id: B9K833
names: Cofactor
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: Divalent metal ions. Mg(2+) is the most effective.

309803:CTN RS07580
gene id: 309803:CTN_RS07580
uniprot id: B9K9R0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

309803:CTN RS02225
gene id: 309803:CTN_RS02225
uniprot id: B9K6P6
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06300
gene id: 309803:CTN_RS06300
uniprot id: B9K904
names: Similarity
messages: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family.

309803:CTN RS09265
gene id: 309803:CTN_RS09265
uniprot id: B9KAQ4
names: Similarity
messages: Belongs to the UPF0047 family.

309803:CTN RS07110
gene id: 309803:CTN_RS07110
uniprot id: B9K9G3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS09200
gene id: 309803:CTN_RS09200
uniprot id: B9KAP1
names: Cofactor
messages: Binds 1 zinc ion per subunit.

309803:CTN RS06635
gene id: 309803:CTN_RS06635
uniprot id: B9K970
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

309803:CTN RS08545
gene id: 309803:CTN_RS08545
uniprot id: B9KAA5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

309803:CTN RS00405
gene id: 309803:CTN_RS00405
uniprot id: B9KB67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

309803:CTN RS01450
gene id: 309803:CTN_RS01450
uniprot id: B9KBS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

309803:CTN RS00560
gene id: 309803:CTN_RS00560
uniprot id: B9KB99
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

309803:CTN RS00655
gene id: 309803:CTN_RS00655
uniprot id: B9KBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

309803:CTN RS06165
gene id: 309803:CTN_RS06165
uniprot id: B9K8X7
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Monomer.

309803:CTN RS07640
gene id: 309803:CTN_RS07640
uniprot id: B9K9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

309803:CTN RS02210
gene id: 309803:CTN_RS02210
uniprot id: B9K6P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

309803:CTN RS01595
gene id: 309803:CTN_RS01595
uniprot id: B9KBV5
names: Similarity
messages: Belongs to the shikimate dehydrogenase family.

309803:CTN RS08095
gene id: 309803:CTN_RS08095
uniprot id: B9KA17
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS07680
gene id: 309803:CTN_RS07680
uniprot id: B9K9T0
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS09210
gene id: 309803:CTN_RS09210
uniprot id: B9KAP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmG family. TrmFO subfamily.
messages: Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
messages: Cytoplasm

309803:CTN RS08320
gene id: 309803:CTN_RS08320
uniprot id: B9KA60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

309803:CTN RS02590
gene id: 309803:CTN_RS02590
uniprot id: B9K6V6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell inner membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

309803:CTN RS03600
gene id: 309803:CTN_RS03600
uniprot id: B9K7H2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

309803:CTN RS01865
gene id: 309803:CTN_RS01865
uniprot id: B9KC07
names: Similarity
messages: Belongs to the glycosyl hydrolase 42 family.

309803:CTN RS01765
gene id: 309803:CTN_RS01765
uniprot id: B9KBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS04980
gene id: 309803:CTN_RS04980
uniprot id: B9K8A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

309803:CTN RS06855
gene id: 309803:CTN_RS06855
uniprot id: B9K9B3
names: Similarity
messages: Belongs to the glycosyl hydrolase 53 family.

309803:CTN RS06750
gene id: 309803:CTN_RS06750
uniprot id: B9K992
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS04235
gene id: 309803:CTN_RS04235
uniprot id: B9K7V3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

309803:CTN RS06990
gene id: 309803:CTN_RS06990
uniprot id: B9K9E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

309803:CTN RS01445
gene id: 309803:CTN_RS01445
uniprot id: B9KBS3
names: Function
names: Similarity
names: Subunit
messages: Associates with stalled 50S ribosomal subunits.
messages: Belongs to the NEMF family.
messages: Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.

309803:CTN RS04915
gene id: 309803:CTN_RS04915
uniprot id: B9K887
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

309803:CTN RS05405
gene id: 309803:CTN_RS05405
uniprot id: B9K8I1
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS06975
gene id: 309803:CTN_RS06975
uniprot id: B9K9D7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

309803:CTN RS01815
gene id: 309803:CTN_RS01815
uniprot id: B9KBZ7
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS02150
gene id: 309803:CTN_RS02150
uniprot id: B9K6N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

309803:CTN RS03365
gene id: 309803:CTN_RS03365
uniprot id: B9K7B9
names: Similarity
messages: Belongs to the UPF0166 family.

309803:CTN RS01195
gene id: 309803:CTN_RS01195
uniprot id: B9KBM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

309803:CTN RS09350
gene id: 309803:CTN_RS09350
uniprot id: B9KAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

309803:CTN RS04005
gene id: 309803:CTN_RS04005
uniprot id: B9K7Q7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

309803:CTN RS04805
gene id: 309803:CTN_RS04805
uniprot id: B9K865
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

309803:CTN RS00270
gene id: 309803:CTN_RS00270
uniprot id: B9KB38
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS03715
gene id: 309803:CTN_RS03715
uniprot id: B9K7J7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

309803:CTN RS05715
gene id: 309803:CTN_RS05715
uniprot id: B9K8P2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

309803:CTN RS00065
gene id: 309803:CTN_RS00065
uniprot id: B9KAZ3
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS07670
gene id: 309803:CTN_RS07670
uniprot id: B9K9S8
names: Similarity
messages: Belongs to the ArsC family.

309803:CTN RS08580
gene id: 309803:CTN_RS08580
uniprot id: B9KAB2
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

309803:CTN RS00470
gene id: 309803:CTN_RS00470
uniprot id: B9KB80
names: Similarity
messages: Belongs to the SfsA family.

309803:CTN RS04105
gene id: 309803:CTN_RS04105
uniprot id: B9K7S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell inner membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

309803:CTN RS08310
gene id: 309803:CTN_RS08310
uniprot id: B9KA58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

309803:CTN RS05605
gene id: 309803:CTN_RS05605
uniprot id: B9K8M0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS02060
gene id: 309803:CTN_RS02060
uniprot id: B9KC50
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

309803:CTN RS06475
gene id: 309803:CTN_RS06475
uniprot id: B9K937
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
messages: Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
messages: Homodimer.

309803:CTN RS02010
gene id: 309803:CTN_RS02010
uniprot id: B9KC39
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arabinose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of L-arabinose to L-ribulose.

309803:CTN RS09275
gene id: 309803:CTN_RS09275
uniprot id: B9KAQ6
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

309803:CTN RS08080
gene id: 309803:CTN_RS08080
uniprot id: B9KA14
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS09280
gene id: 309803:CTN_RS09280
uniprot id: B9KAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.

309803:CTN RS09525
gene id: 309803:CTN_RS09525
uniprot id: B9KAV6
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

309803:CTN RS02725
gene id: 309803:CTN_RS02725
uniprot id: B9K6Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein uL14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein uL14 (rplN).

309803:CTN RS04695
gene id: 309803:CTN_RS04695
uniprot id: B9K844
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

309803:CTN RS01345
gene id: 309803:CTN_RS01345
uniprot id: B9KBQ2
names: Similarity
messages: Belongs to the glutamate synthase family.

309803:CTN RS09065
gene id: 309803:CTN_RS09065
uniprot id: B9KAL1
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS08915
gene id: 309803:CTN_RS08915
uniprot id: B9KAI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

309803:CTN RS04655
gene id: 309803:CTN_RS04655
uniprot id: B9K837
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetokinase family.
messages: Cytoplasm

309803:CTN RS02025
gene id: 309803:CTN_RS02025
uniprot id: B9KC42
names: Cofactor
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.

309803:CTN RS03710
gene id: 309803:CTN_RS03710
uniprot id: B9K7J6
names: Function
names: Similarity
messages: Belongs to the type-2 OGG1 family.
messages: Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).

309803:CTN RS05950
gene id: 309803:CTN_RS05950
uniprot id: B9K8T8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

309803:CTN RS00255
gene id: 309803:CTN_RS00255
uniprot id: B9KB33
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

309803:CTN RS01395
gene id: 309803:CTN_RS01395
uniprot id: B9KBR2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

309803:CTN RS02975
gene id: 309803:CTN_RS02975
uniprot id: B9K736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

309803:CTN RS04125
gene id: 309803:CTN_RS04125
uniprot id: B9K7T2
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

309803:CTN RS05045
gene id: 309803:CTN_RS05045
uniprot id: B9K8B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

309803:CTN RS05975
gene id: 309803:CTN_RS05975
uniprot id: B9K8U3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

309803:CTN RS05280
gene id: 309803:CTN_RS05280
uniprot id: B9K8F9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional regulatory Rex family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.

309803:CTN RS02400
gene id: 309803:CTN_RS02400
uniprot id: B9K6T1
names: Similarity
messages: Belongs to the ClpA/ClpB family.

309803:CTN RS02495
gene id: 309803:CTN_RS02495
uniprot id: B9K6U1
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

309803:CTN RS01980
gene id: 309803:CTN_RS01980
uniprot id: B9KC32
names: Similarity
messages: Belongs to the aldose epimerase family.

309803:CTN RS02075
gene id: 309803:CTN_RS02075
uniprot id: B9KC53
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

309803:CTN RS09390
gene id: 309803:CTN_RS09390
uniprot id: B9KAS9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

309803:CTN RS09260
gene id: 309803:CTN_RS09260
uniprot id: B9KAQ3
names: Subcellular Location Annotation
messages: Membrane

309803:CTN RS08680
gene id: 309803:CTN_RS08680
uniprot id: B9KAD2
names: Similarity
messages: Belongs to the GSP E family.

309803:CTN RS07620
gene id: 309803:CTN_RS07620
uniprot id: B9K9R8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS04430
gene id: 309803:CTN_RS04430
uniprot id: B9K7Z1
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

309803:CTN RS03940
gene id: 309803:CTN_RS03940
uniprot id: B9K7P3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endonuclease V family.
messages: Cytoplasm
messages: DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.

309803:CTN RS01630
gene id: 309803:CTN_RS01630
uniprot id: B9KBW2
names: Cofactor
names: Similarity
messages: Belongs to the UPF0313 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

309803:CTN RS07355
gene id: 309803:CTN_RS07355
uniprot id: B9K9L3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

309803:CTN RS07115
gene id: 309803:CTN_RS07115
uniprot id: B9K9G4
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

309803:CTN RS09245
gene id: 309803:CTN_RS09245
uniprot id: B9KAQ0
names: Similarity
messages: Belongs to the peptidase U62 family.

309803:CTN RS03695
gene id: 309803:CTN_RS03695
uniprot id: B9K7J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

309803:CTN RS07615
gene id: 309803:CTN_RS07615
uniprot id: B9K9R7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

309803:CTN RS05000
gene id: 309803:CTN_RS05000
uniprot id: B9K8A4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

309803:CTN RS04265
gene id: 309803:CTN_RS04265
uniprot id: B9K7W0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

309803:CTN RS07425
gene id: 309803:CTN_RS07425
uniprot id: B9K9M8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

309803:CTN RS00415
gene id: 309803:CTN_RS00415
uniprot id: B9KB69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. PolC subfamily.
messages: Cytoplasm
messages: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

309803:CTN RS04770
gene id: 309803:CTN_RS04770
uniprot id: B9K859
names: Cofactor
names: Similarity
messages: Belongs to the Fur family.
messages: Binds 1 Mn(2+) or Fe(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.

309803:CTN RS00275
gene id: 309803:CTN_RS00275
uniprot id: B9KB39
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with bS18 to 16S ribosomal RNA.

309803:CTN RS04025
gene id: 309803:CTN_RS04025
uniprot id: B9K7R2
names: Cofactor
messages: Binds 1 [2Fe-2S] cluster per subunit.

309803:CTN RS03580
gene id: 309803:CTN_RS03580
uniprot id: B9K7G8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

309803:CTN RS09235
gene id: 309803:CTN_RS09235
uniprot id: B9KAP8
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

309803:CTN RS06220
gene id: 309803:CTN_RS06220
uniprot id: B9K8Y8
names: Similarity
messages: Belongs to the peptidase M16 family.